CN103006322A - Microwave generator - Google Patents

Microwave generator Download PDF

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Publication number
CN103006322A
CN103006322A CN2012105279110A CN201210527911A CN103006322A CN 103006322 A CN103006322 A CN 103006322A CN 2012105279110 A CN2012105279110 A CN 2012105279110A CN 201210527911 A CN201210527911 A CN 201210527911A CN 103006322 A CN103006322 A CN 103006322A
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CN
China
Prior art keywords
transmission line
probe
wall
pipe
microwave generator
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Pending
Application number
CN2012105279110A
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Chinese (zh)
Inventor
奈杰尔·克罗宁
皮特·克莱格
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Microsulis Ltd
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Microsulis Ltd
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Publication date
Application filed by Microsulis Ltd filed Critical Microsulis Ltd
Priority to CN2012105279110A priority Critical patent/CN103006322A/en
Publication of CN103006322A publication Critical patent/CN103006322A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a microwave generator, which comprises a probe containing an elongated rod (14), a microwave radiating portion (15), a transmission line (17) and an elongated distributary constructional element (19), wherein the elongated rod (14) is provided with an external tubular wall (18); the microwave radiating portion (15) is arranged at a far end of the elongated rod (14); the inner part of the external tubular wall (18) extends to the transmission line (17) of the radiating portion; the elongated distributary constructional element (19) and the transmission line (17) longitudinally and synergetically extend along the elongated rod (14); and the side wall of the transmission line (17) is mutually contacted with the side wall of the distributary constructional element (19), and is contacted with the inner surface of the external pipe wall (18) at a discrete position of two separated spaces, so that a pair of runners (20 and 21) is formed in the elongated rod (14); and when the microwave generator is used, a cooling liquid flows from the runner (20) and returns from the other runner (21); and the probe is not complex in structure and is easy to assemble.

Description

Microwave generator
This case is that application number is 200980104359.0, and the applying date is on February 5th, 2009, and name is called dividing an application of " microwave generator "
Technical field
The present invention relates to a kind of medical microwave generator.
Background technology
As everyone knows, utilize the microwave generator bodily tissue of ablating, the tissue around such microwave generator can heat and destroy.A kind of application of this generator is to be used in for example Noninvasive treatment of cancer of liver of human internal organs.GB2415630 discloses a kind of generator of the above-mentioned type, and it comprises and has the probe that can insert the elongate rod in the patient body.The near-end of probe comprises the handle that connects together with the external microwave generator by elongated pliable and tough cable.Elongated microwave transmission line extends to placing or adjoining in the radiation of probe distal is most advanced and sophisticated from handle in probe interior.During use, the tissue around in the Microwave Field Heating that penetrates from the tip and the regional area of ablating.
The shortcoming of above-mentioned generator is that probe can be because of the many reasons heating.At first, in the transmission line that extends along probe to the tip, there is energy loss, this energy loss heating transmission line and probe peripheral part.Secondly, the microwave energy that gives off can make the probe heating.The 3rd, can return along probe from the heat of ablating.This heating of probe is worthless because it can burn patient the skin at probe point of penetration place or its can the burn patient health adjoin other position of probe rod.In fact, the external temperature of any medical apparatus and instruments of British government's clear should be above 48 °.
In order to overcome the problems referred to above, well-known is mobile so that the cooling probe along probe by the liquid of for example normal saline.In use, liquid goes out to enter body cavity on every side from the orifice flow of probe distal.The shortcoming that arranges the like this wound that has been liquid filling and inadvisable ground or flow out or flow to health.In addition, the microwave energy of radiation can make endoceliac liquid heating.
In order to overcome the problems referred to above, WO2005/011049, DE2407559 and US4375220 all disclose a kind of microwave generator, and wherein liquid coolant flows to far-end along a runner along probe and then returns along another runner.
In order to realize this goal, each above-mentioned generator comprises cooling tube or the former of complex array in probe, and it defines and flows and backward channel.Obviously, the microwave generator probe is preferably thinner, in order to they are used by Noninvasive as far as possible.Yet being used for the pipe of above-mentioned generator or the shortcoming of former is to need relatively large flowing and backward channel in order to reach required flow velocity, obviously the overall diameter of the corresponding increase probe of this meeting.In addition, in order to make things convenient for the insertion of pipe or former, probe also needs corresponding large diameter.
Summary of the invention
We design a kind of microwave generator of alleviating the problems referred to above now.
According to the present invention, a kind of microwave generator is provided, has the probe that comprises elongated bar, this bar has outer tubular wall, place the microwave radiating portion of bar far-end and extend to the transmission line of described radiating portion in described outer tubular wall inside, wherein elongated part flow arrangement contacts with the inner surface sealing of described tube wall along the length of the inner discrete positions of extending and separating along two spaces that center on the tube wall periphery of described outer tubular wall, the periphery of described part flow arrangement does not contact with described tube wall between above-mentioned two positions, in order to limit the first and second discrete runners, it is for transporting liquid coolant along described bar longitudinal extension.
In use, liquid coolant flows with the cooling probe along first passage, and then this liquid coolant is returned along second channel.Because part flow arrangement and outer pipe wall define runner jointly, avoided the needs of complicated pipe and former, and therefore the diameter of probe can minimize.Part flow arrangement also respective straight patches into probe, and this will be described hereinafter.
In one embodiment, part flow arrangement comprises the one-way distributing member that has with the variform outer cross shape of the internal cross section of outer pipe wall.For example, the outer cross shape of part flow arrangement can be circular, and the internal cross section shape of tube wall can be oval, and perhaps vice versa.
Described shunting member can comprise the hollow pipe that carries described transmission line, and perhaps transmission line self can form described shunting member.
In another alternative embodiment, described part flow arrangement comprises described transmission line and the shunting member of the elongation of extending along the vertical collaboration of described bar with described transmission line, the sidewall of transmission line is in contact with one another with the sidewall of shunting member, and the discrete positions of separating in described two spaces contacts with the inner surface of described outer pipe wall.
Described shunting member can be relatively thin, and preferably diameter is equal to or greater than external diameter poor of the internal diameter of described outer tubular wall of bar and described transmission line substantially.
Usually hope can perceptual parameters for example in the temperature at radiation tip.In order to realize this goal, described shunting member can comprise one or more wire of carrying to pipe or the cable of bar far-end, and in use, wire can transmit the measuring-signal that comes from the sensor that is positioned at the bar far-end.
Transmission line preferably comprises and is connected to sensor and forms the right conductor of signal with the wire of shunting member.
Preferably, described shunting member comprises pipe or the cable of at least one wire that carries thermocouple, and a described wire is preferably made by the first metal of for example constantan.Described the first plain conductor far-end preferably its tip place is connected on the described conductor of transmission line, and this conductor is made by the second metal of for example copper.Preferably, described bimetallic main body places the far-end of described the first plain conductor to connect in order to form reliably between described metal.Described bimetallic main body preferably is electrically connected with the described conductor of transmission line in probe.
Described runner preferably has substantially the cross-sectional area that equates, in conjunction with after the flow channel cross-section area internal cross section area that preferably the equals outer tubular wall cross-sectional area that deducts transmission line deduct and shunt the element cross-section area.
Preferably, the far-end of part flow arrangement stops before the described radiant section of probe, intersects in order to form between described runner.
Preferably, at least one described runner seals by sealing gasket or other member at the probe near-end.
Preferably, the proximal extension of bar is in menifold, and menifold preferably forms the handle of probe.
Preferably, this menifold comprises the first and second separate spaces of mutual sealed separation, and described the first and second runners link to each other with described the first and second separate spaces respectively.
Preferably, the first and second separate spaces of menifold are arranged on longitudinally corresponding position of rod axis.
Preferably, in outer tubular wall formation one hole of bar near-end, described hole is connected a described runner with a described separate space of menifold.
Preferably, menifold separate space comprises the mouth that connects the outer flow duct of transporting liquid coolant.The preferred pressure source from pump or other liquid coolant of this stream pipe transports liquid coolant and enters in the probe.
Preferably, another separate space of menifold comprises the mouth of the pliable and tough cable far-end that is connected to the generator elongation, and this cable extends from microwave radiation source, and described cable comprises the stream pipe that transports described liquid coolant.The stream pipe of cable preferably is transported to liquid coolant in drain pipe or the collection container from probe.Liquid is further to cool off owing to energy loss and the cable of heating along flowing in of cable.
Preferably, the near-end of cable comprises mouth, and it is as entrance or the outlet of cable stream pipe.
According to the present invention, a kind of method of making the microwave generator probe also is provided, comprise the pipe that elongation is provided, make pipe perpendicular to the distortion of its longitudinal axis, then the part flow arrangement that elongates is inserted in the pipe after the distortion releasing tube so that its reinstatement.
The distortion of pipe so that the part flow arrangement that elongates be easy to be inserted in the pipe.In case be released, pipe restore to the original state and with the part flow arrangement that elongates compress into it with the inner surface of wall in two positions that spaced-apart positions contacts that center on the tube wall periphery.By this way, form the runner of two airtight separations along pipe.
Preferably, the method comprises in the transmission line insertion tube that will elongate.Elongating transmission line can form separately described part flow arrangement or together form described part flow arrangement together with the shunting member that elongates.Under latter event, transmission line and shunting member can be inserted in the pipe or successively in the insertion tube simultaneously.Under latter event, can before distortion, will shunt in one of member insertion tube.
Description of drawings
Now only by example and with reference to the description of drawings embodiments of the invention, wherein:
Fig. 1 is the first embodiment sketch map according to microwave generator of the present invention;
Fig. 2 is the perspective outline drawing of the probe distal of Fig. 1 generator;
Fig. 3 is the perspective outline drawing of near-end of bar of the probe of Fig. 1 generator;
Fig. 4 is the probe near-end of Fig. 1 generator and the perspective outline drawing of microwave feed cable;
Fig. 5 is the partial perspective outline drawing of menifold of the probe of Fig. 1 device;
Fig. 6 is the perspective outline drawing of the feed cable output cavity of Fig. 1 generator;
Fig. 7 is the perspective diagram of manufacture method of bar of the probe of key diagram 1 generator;
Fig. 8 is according to the longitudinal sectional view that passes probe rod among microwave generator probe the second embodiment of the present invention;
Fig. 9 is the cutaway view along Fig. 8 center line IX-IX; And
Figure 10 is the transverse sectional view of passing probe rod according among microwave generator probe the 3rd embodiment of the present invention.
The specific embodiment
Fig. 1 with reference to the accompanying drawings shows the microwave generator probe, comprises the microwave generator 10 that is connected to generator probe 11 via the pliable and tough feed cable 12 that elongates.Probe 11 comprises handle portion 13 and by the bar part 14 of handle 13 extended elongations.In use, generator 10 produces 11 microwave signals that transmit along feed cable 12 to probe.Then this microwave signal is sent to the radiation tip 15 of probe distal along the bar 14 of probe.
Fig. 2 with reference to the accompanying drawings, bar 14 comprise the tubular wall of the outside elongation of being made by rustless steel.Coaxial transmission line 17 is in tube wall 14 interior extensions, and transmission line 17 is coupled on the microwave feed cable 12 at its near-end, is coupled on the active antenna 16 that is arranged in the probe 11 most advanced and sophisticated 15 at its far-end.The shunting member 19 of the elongation that exists with solid cable or wire form and cardinal principle part common extend of coaxial transmission line 17 along its length direction, member 19 terminal short distances are away from active antenna 16.
Transmission line 17 and shunting member 19 in conjunction with after slightly larger in diameter in the internal diameter of outer tubular wall 18 so that transmission line 17 and shunting member can both contact with the inner surface of outer tubular wall 18 utterly, and mutual cardinal principle along bar 14 length directions partly contacts.Transmission line 17 and shunting member 19 define two runners 20,21 by this way jointly, and they vertically extend to the point that shunting member 19 stops from near-end along bar 14.Article two, runner 20,21 all is connected to each other except the point that stops at shunting member 19.
Fig. 3 with reference to the accompanying drawings and Fig. 4, a runner 20 is positioned at member 22 sealings of bar 14 near-ends.Outer pipe wall 18 at bar 14 near-ends forms a plurality of holes 27, and these holes 27 are communicated with the runner 20 of sealing.The proximal extension of bar 14 enters to be arranged at 23 li of menifolds in the handle 13 of probe 11.Menifold 23 is generally cylindrical and is divided into two chambeies 24,25 that axially arrange by boundary wall 26, and this boundary wall is extended normal to the longitudinal axis of bar 14.The proximal extension of bar 14 advances in the menifold 23 and passes boundary wall 26, so that the distal chamber 24 of menifold 23 is led in hole 27, second (non-tight) runner 21 of bar 14 leads to the near-end chamber 25 of menifold 23.Entrance 28 is extended by the sidewall radially outward of menifold 23, and entrance 28 is connected with the distal chamber 24 of menifold 23.
The proximal end wall 13 of menifold 23 is connected on the feed cable 12, and this feed cable 12 comprises that outer tube 28 and loosely are at the coaxial cable 29 of outer tube 28 interior extensions.Coaxial cable 29 passes proximal end wall 30 extensions of menifold 23 and is connected on the coaxial transmission line 17 by shaft coupling 31 in chamber 25.Pipe 28 distal seal is coupled on the hole of proximal end wall of menifold 23, leads to the near-end chamber 25 of menifold 23 so that manage 28 inside.
Fig. 6 with reference to the accompanying drawings, the near-end of feed cable 12 are connected to the cylindrical output cavity 32 of elongation.The near-end of the pipe 28 of feed cable 12 is coupled to output cavity 32, leads to output cavity 32 so that manage 28 inside.Coaxial cable 29 passes output cavity 32 and extends to the coaxial connector 34 that is positioned on the 32 proximal end wall outer surfaces of chamber.Outlet 32 is extended from the sidewall radially outward of output cavity 32.
In use, coaxial connector 34 is connected on the microwave generator 10.The entrance 28 of menifold 23 is connected on the pump by elongating the pipe (not shown).Outlet 33 is connected on the collection container via elongating the pipe (not shown).When energising, pump extracts liquid coolant and enters in the distal chamber 24 of menifold 23 by entrance 28.Liquid coolant then flow through on the outer pipe wall 18 of bar 14 hole 27 and flow in the runner 20.Liquid coolant is then along bar 14 longitudinal flows, thus the outer wall of cooling rod 18 and transmission line 17.Except the point of shunting member 19 terminations, liquid coolant flows to another runner 21 of bar 14 far-ends from runner 20.Then liquid coolant is returned via coolant flow channel 21 along bar 14, then flows into the near-end chamber 25 of menifold 23.Liquid flows out menifold 23 and flows into feed cable 12, then flows in the annular channel that is limited by outer tube 28 and coaxial cable 29 along cable 12.Then liquid flow to collection container by exporting 33 outflow output cavities 32.By this way, liquid coolant has also been cooled off coaxial cable 29.
Fig. 7 with reference to the accompanying drawings, by pressing outer pipe wall 18, along the longitudinal axis of tube wall 18, tube wall 18 transverse section become ellipse, and coaxial transmission line 17 and shunting member 19 are inserted in the outer pipe wall 18 of bar 14.Transmission line 17 is with shunting member 19 so in the outer pipe wall 18 after can being easily inserted into distortion.In case be inserted into, external force can be removed, thereby outer pipe wall 18 is restored to the original state, so that coaxial transmission line 17 and shunting member 19 mutually compress and mutually compress with outer pipe wall 18.
Fig. 8 with reference to the accompanying drawings and Fig. 9 show alternative embodiment of microwave generator probe, the probe of its probe similar Fig. 1-7, and same parts provide with same reference number.In this embodiment, the shunting member 19 of elongation is replaced by tubule, is for example made by rustless steel.The covered wire 36 of the constantan that elongates extends through pipe 35 from gauge 43.The far-end of constantan wire is on-insulated, and the main body 37 of copper product places above the exposed conductor of constantan wire 36.Transmission line 17 comprises an outer copper sleeve 40.The center conductor 38 that elongates therefrom insulate in copper sleeve 40 interior extensions and by insulated sleeve 39.Copper main body 37 above the constantan wire 36 contacts with the copper sleeve 40 of transmission line 17.The diameter of copper main body 37 equals to manage 35 diameter substantially, so that copper sleeve 40 close contacts of it and transmission line 17.The outer surface of copper main body 37 can be electroplated to guarantee reliably to contact with the copper sleeve 40 of transmission line 17.The near-end of copper conductor 40 is connected on the gauge 43 by wire 42.Pipe 35 is preferably sealed by other member of constantan wire 36 or prevention liquid flow.In this way, avoided the risk of liquid utilization pipe 35 as return path.
Obviously the closed circuit of thermocouple instrument 43 has just been created by the copper sleeve 40 of constantan wire 36, copper main body 37 and transmission line 17.Copper constantan nodes in the main body 37 form the thermocouple junction of the tip temperature indication that can be used to offer probe 11.
Two thermocouple wires 36,42 that extend from gauge 43 preferably extend into output menifold 32, and along being extended by the cable 12 in the annular channel that limits between outer tube 28 and the coaxial cable 29.Then wire 36,42 extends to the bar 14 of probe 11 by menifold 13.This set helps to hide wire 36,42, and improves the overall appearance of generator.
Figure 10 with reference to the accompanying drawings shows alternative embodiment of microwave generator probe, and it is similar to the embodiment of Fig. 8 and Fig. 9, and same parts provide with same reference number.In this embodiment, independent shunting member 19 is deleted, and as an alternative, transmission line 17 effects are himself to define two runners 120,121.This is generally oval-shaped outer pipe wall 118 and realizes by the cross section being set for bar 14.By the longitudinal axis along wall, make the cross-sectional deformability of wall, until it is becoming common circle in shape, transmission line 17 is inserted in the outer wall 118: this can eliminate deformation force so that transmission line 17 contacts in radially relative position with outer wall 118 when the time comes so that transmission line 17 is inserted into.
Probe according to microwave generator of the present invention is structurally fairly simple and cheap, yet probe is cooled off reliably.

Claims (6)

1. form the method for microwave generator probe, comprise the pipe that elongation is provided, make pipe perpendicular to its longitudinal axis distortion, in the pipe after the part flow arrangement insertion distortion of elongating, and releasing tube is so that its reinstatement.
2. the method for claim 1 comprises in the transmission line insertion tube that elongates.
3. method as claimed in claim 1 or 2 comprises in the shunting member insertion tube that will elongate.
4. as being subordinated to the method claimed in claim 3 of claim 2, comprise simultaneously with in transmission line and the shunting member insertion tube.
5. as be subordinated to the method claimed in claim 3 of claim 2, comprise in transmission line and the shunting member successively insertion tube.
6. method as claimed in claim 5 is included in before being out of shape the situation in transmission line or the shunting member insertion tube.
CN2012105279110A 2009-02-05 2009-02-05 Microwave generator Pending CN103006322A (en)

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CN2009801043590A Division CN101969875A (en) 2008-02-09 2009-02-05 A microwave applicator

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108430369A (en) * 2015-12-07 2018-08-21 科瑞欧医疗有限公司 For in therapentic part microwave radiation energy and distributing the electrosurgical unit of liquid

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5201756A (en) * 1990-06-20 1993-04-13 Danforth Biomedical, Inc. Radially-expandable tubular elements for use in the construction of medical devices
WO2002061880A2 (en) * 2001-01-31 2002-08-08 Cnr Consiglio Nazionale Delle Ricerche Interstitial microwave antenna with miniaturized choke for hyperthermia and surgery
US20050245920A1 (en) * 2004-04-30 2005-11-03 Vitullo Jeffrey M Cell necrosis apparatus with cooled microwave antenna
US7195611B1 (en) * 2002-12-31 2007-03-27 Advanced Cardiovascular Systems, Inc. Rapid exchange balloon catheter having a reinforced inner tubular member
WO2007112081A1 (en) * 2006-03-24 2007-10-04 Micrablate Transmission line with heat transfer ability

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5201756A (en) * 1990-06-20 1993-04-13 Danforth Biomedical, Inc. Radially-expandable tubular elements for use in the construction of medical devices
WO2002061880A2 (en) * 2001-01-31 2002-08-08 Cnr Consiglio Nazionale Delle Ricerche Interstitial microwave antenna with miniaturized choke for hyperthermia and surgery
US7195611B1 (en) * 2002-12-31 2007-03-27 Advanced Cardiovascular Systems, Inc. Rapid exchange balloon catheter having a reinforced inner tubular member
US20050245920A1 (en) * 2004-04-30 2005-11-03 Vitullo Jeffrey M Cell necrosis apparatus with cooled microwave antenna
WO2007112081A1 (en) * 2006-03-24 2007-10-04 Micrablate Transmission line with heat transfer ability

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108430369A (en) * 2015-12-07 2018-08-21 科瑞欧医疗有限公司 For in therapentic part microwave radiation energy and distributing the electrosurgical unit of liquid

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Application publication date: 20130403