CN102969218A - Multi-channel mixing ionization source and working method thereof - Google Patents
Multi-channel mixing ionization source and working method thereof Download PDFInfo
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- CN102969218A CN102969218A CN2012104345261A CN201210434526A CN102969218A CN 102969218 A CN102969218 A CN 102969218A CN 2012104345261 A CN2012104345261 A CN 2012104345261A CN 201210434526 A CN201210434526 A CN 201210434526A CN 102969218 A CN102969218 A CN 102969218A
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- H01—ELECTRIC ELEMENTS
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Abstract
The invention provides a multi-channel ionization source. The ionization source comprises an ion transmission channel and at least two ion channels, wherein the transmission channel comprises a first repulsion electrode and an ion lens, each of the ion channels comprises a repulsion electrode, an ionization source, a transmission electrode and a switching electrode, the included angle formed by at least two ion channels and the ion transmission channel is in a range from 0 degree to 180 degrees, and ions generated by any ionization source enter the ion lens through the transmission electrodes and the switching electrodes under the action of the transmission electrodes, the first repulsion electrode and the repulsion electrodes of the ion channels. The switching is automatic, and a plurality of objects are detected at the same.
Description
Technical field
The present invention relates to ionization source, particularly multichannel ionization source and method of work thereof.
Background technology
Gas chromatography-mass spectrometry instrument is one of important member of field of analytic instrument, the organic molecule that mixes enters mass spectrum after separating through gas chromatographic column, mass spectrum makes the organic molecule ionization, and make various ions under the effect in electric field or magnetic field, separate according to the mass-to-charge ratio size, and detecting its corresponding intensity, the mass signal that obtains can be carried out Qualitative Identification and quantitative analysis to material.
The mass detector that is used for being connected with gas-chromatography has electron ionization (EI) source and two kinds of ion sources of chemi-ionization (CI) usually, two kinds of ion sources structurally have certain difference, to switch to from the EI source work of CI source, must carry out ionogenic replacing, usually need to close whole chromatogram and mass spectrometer is realized this replacing.In more applications, analyze different materials, need to use different gas chromatographic columns, also need to close the replacing of chromatogram and mass spectrometer realization chromatographic column, this Renewal process is complicated often, and the detection performance after the start does not often have highly reliably consistency again.
Can run into above-mentioned mass spectrum in a lot of analyzing and testing fields and use problem, for example detect strong polarity and the low pole organic substance need to be changed chromatographic column, for obtaining the molecular ion information of material, need to change ion source, in some GC-MS instrument, realized the twin columns sample introduction, two root chromatogram columns namely are installed in same set of column oven system, two root chromatogram columns insert in the ion source simultaneously, and this occupation mode has been removed the problem of changing chromatographic column from, but still analyze when can not realize two class materials.
Summary of the invention
In order to solve the deficiency in the above-mentioned prior art scheme, the invention provides a kind of multichannel mixing ionization source and method of work thereof, realize the switching automation, detected the purposes such as multiple object simultaneously.
The objective of the invention is to be achieved through the following technical solutions:
The multichannel ionization source comprises the ion transfer passage, and described transmission channel comprises the first repulsion electrode, ion lens; Described multichannel ionization source further comprises:
At least two-way ionization channels, every road ionization channels comprise repulsion electrode, ion source, transmission electrode and switch electrode;
Described at least two-way ionization channels and the interchannel angle of described ion transfer are greater than 0 degree and less than 180 degree, so that under the repulsion electrode effect of transmission electrode, the first repulsion electrode, ionization channels, the ion that arbitrary ion source produces enters described ion lens by transmission electrode, switching electrode.
According to above-mentioned multichannel ionization source, alternatively, described ion source connects chromatographic column.
According to above-mentioned multichannel ionization source, preferably, described ionization channels and the interchannel angle of described ion transfer are 90 degree.
According to above-mentioned multichannel ionization source, preferably, described ion source is EI ion source or CI ion source.
Purpose of the present invention also is achieved by the following technical programs:
According to the method for work of above-mentioned multichannel ionization source, described method of work may further comprise the steps:
(A1) select the ionization channels that is suitable for according to object to be measured;
(A2) adjust the switching electrode of described applicable ionization channels, so that the ion after the ionization enters described ion transfer passage under the effect of the repulsion electrode of described applicable ionization channels, transmission electrode, under the effect of described the first repulsion electrode, ion lens, realize ion deflecting afterwards, thereby enter described ion lens.
According to above-mentioned method of work, preferably, described ion source is worked simultaneously, thereby detects when realizing at least two-way object to be measured.
Compared with prior art, the beneficial effect that has of the present invention is:
1, uses different ion sources by selectivity, can change the switching that ion source can be realized electron ionization sources (EI source) and chemical ionization source (CI source);
2, chromatographic column need not be changed, the detection of different types of material can be realized;
Detect when 3, can realize the polytype organic substance, greatly improve detection efficiency.
Description of drawings
With reference to accompanying drawing, disclosure of the present invention will be easier to understand.Those skilled in the art are understood that easily: these accompanying drawings only are used for illustrating technical scheme of the present invention, and are not to be intended to protection scope of the present invention is construed as limiting.Among the figure:
Fig. 1 is the structure diagram according to the multichannel mixing ionization source of the embodiment of the invention 1.
Embodiment
Fig. 1 and following declarative description optional execution mode of the present invention how to implement with instruction those skilled in the art and reproduce the present invention.In order to instruct technical solution of the present invention, simplified or omitted some conventional aspects.Those skilled in the art should understand that the modification that is derived from these execution modes or replace will be within the scope of the invention.Those skilled in the art should understand that following characteristics can make up to form a plurality of modification of the present invention in every way.Thus, the present invention is not limited to following optional execution mode, and is only limited by claim and their equivalent.
Embodiment 1:
Fig. 1 has schematically provided the structure diagram of the multichannel mixing ionization source of the embodiment of the invention, and as shown in Figure 1, described ionization source comprises:
Comprise the ion transfer passage, described transmission channel comprises the first repulsion electrode 3, ion lens (such as three electrodes 4,5,6); Described ion transfer passage is the state of the art, does not repeat them here.
At least two-way ionization channels, every road ionization channels comprise repulsion electrode, ion source 1, transmission electrode and switch electrode 2, and this repulsion electrode, ion source, transmission electrode and to switch electrode all are state of the art do not repeat them here.As, described ion source can be selected the ion source of CI ion source, EI ion source or other type.Alternatively, described ion source connects chromatographic column, thereby forms chromatograph-mas spectrometer.
Described at least two-way ionization channels and the interchannel angle of described ion transfer are greater than 0 degree and less than 180 degree, preferably 90 spend, so that under the repulsion electrode effect of transmission electrode, the first repulsion electrode, ionization channels, the ion that arbitrary ion source produces enters described ion lens by transmission electrode, switching electrode.
The embodiment of the invention gives the method for work of above-mentioned multichannel ionization source, and described method of work may further comprise the steps:
(A1) select the ionization channels that is suitable for according to object to be measured;
(A2) adjust the switching electrode of described applicable ionization channels, the molecule of object to be measured is bombarded to ionization by electronics in ion source, under the effect of the repulsion electrode of ionization channels and transmission electrode, introduce near the first repulsion electrode, ion is under the effect of this first repulsion electrode and ion lens, direction of motion deflection is finally introduced in the mass analyzer.
Alternatively, described ion source is worked simultaneously, thereby detects when realizing at least two-way object to be measured.
Embodiment 2:
Ionization source and method of work application examples according to the embodiment of the invention 1 specifically are applied in analyzing organic substance in the chromatograph-mas spectrometer.In this application examples, having angle is the two-way ionization channels of 180 degree, and the ion source of every road ionization channels connects chromatographic column, direct ionization object to be measured.The ion source of two-way ionization channels adopts respectively CI ion source, EI ion source, and transmission electrode adopts an electrode with the switching electrode in each road, thus applicable different testing requirement.Described two-way ionization channels and the interchannel angle of described ion transfer are 90 degree, and the voltage that applies on three electrodes of repulsion electrode, transmission electrode, the first repulsion electrode, ion lens in the ionization channels is respectively: 80V, 50V, 40V, 30V, 20V, 10V, thereby realized cation 90 the degree deflections.
Switch in the ionization channels of every road under the control of electrode, above-mentioned ionization source not only divides and detects temporally identical or different object to be measured, can also detect simultaneously identical or different object to be measured.This switching need not artificial better chromatographic column, can automatically realize, and detect when having realized different object, has improved significantly detection efficiency.
Embodiment 3:
Ionization source and method of work application examples according to the embodiment of the invention 1 specifically are applied in analyzing organic substance in the chromatograph-mas spectrometer.In this application examples, having adjacent angle is four road ionization channelses of 90 degree, and the ion source of every road ionization channels connects chromatographic column, direct ionization object to be measured.The ion source of two-way ionization channels adopts CI ion source or EI ion source, thus applicable different testing requirement.Described four road ionization channelses and the interchannel angle of described ion transfer are 120 degree, apply voltage on three electrodes of repulsion electrode, transmission electrode, the first repulsion electrode, ion lens in the ionization channels, thereby realized 120 degree deflections of ionization channels intermediate ion.
Switch in the ionization channels of every road under the control of electrode, above-mentioned ionization source not only divides and detects temporally identical or different object to be measured, can also detect simultaneously identical or different object to be measured.This switching need not artificial better chromatographic column, can automatically realize, and detect when having realized different object, has improved significantly detection efficiency.
Above-described embodiment only the 2, the 3rd has provided exemplarily that angle is the situations of 90 degree, 120 degree between ionization channels and transmission channel, can also be other angle certainly, and such as 30 degree, 60 degree, 150 degree etc., different is to apply different voltage at electrode.This it will be apparent to one skilled in the art that, is to realize that easily embodiment also can be expected to obtain, and can realize purpose of the present invention.
Claims (6)
1. the multichannel ionization source comprises the ion transfer passage, and described transmission channel comprises the first repulsion electrode, ion lens; It is characterized in that: described multichannel ionization source further comprises:
At least two-way ionization channels, every road ionization channels comprise repulsion electrode, ion source, transmission electrode and switch electrode;
Described at least two-way ionization channels and the interchannel angle of described ion transfer are greater than 0 degree and less than 180 degree, so that under the repulsion electrode effect of transmission electrode, the first repulsion electrode, ionization channels, the ion that arbitrary ion source produces enters described ion lens by transmission electrode, switching electrode.
2. multichannel ionization source according to claim 1 is characterized in that: described ion source connection chromatographic column.
3. multichannel ionization source according to claim 1 is characterized in that: described ionization channels and the interchannel angle of described ion transfer are 90 degree.
4. multichannel ionization source according to claim 1, it is characterized in that: described ion source is EI ion source or CI ion source.
5. the method for work of arbitrary described multichannel ionization source according to claim 1-4, described method of work may further comprise the steps:
(A1) select the ionization channels that is suitable for according to object to be measured;
(A2) adjust the switching electrode of described applicable ionization channels, so that the ion after the ionization enters described ion transfer passage under the effect of the repulsion electrode of described applicable ionization channels, transmission electrode, under the effect of described the first repulsion electrode, ion lens, realize ion deflecting afterwards, thereby enter described ion lens.
6. method of work according to claim 5, it is characterized in that: described ion source is worked simultaneously, thereby detects when realizing at least two-way object to be measured.
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| CN2012104345261A CN102969218A (en) | 2012-11-05 | 2012-11-05 | Multi-channel mixing ionization source and working method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106461621A (en) * | 2014-03-31 | 2017-02-22 | 莱克公司 | Gc-tof ms with improved detection limit |
| CN107359100A (en) * | 2017-06-28 | 2017-11-17 | 武汉华星光电技术有限公司 | A kind of ion implantation apparatus and its application method |
| CN108780071A (en) * | 2016-03-07 | 2018-11-09 | 株式会社岛津制作所 | Gaschromatographic mass spectrometric analysis device |
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| GB803168A (en) * | 1956-01-31 | 1958-10-22 | Atomic Energy Authority Uk | Improvements in or relating to mass spectrometers |
| US3796872A (en) * | 1970-12-18 | 1974-03-12 | Ass Elect Ind | Mass spectrometry |
| US20030155500A1 (en) * | 1999-02-09 | 2003-08-21 | Syage Jack A. | Interfaces for a photoionization mass spectrometer |
| US20070057178A1 (en) * | 2005-09-12 | 2007-03-15 | Mds Inc. | Mass spectrometer multiple device interface for parallel configuration of multiple devices |
| CN102308360A (en) * | 2009-01-12 | 2012-01-04 | 萨莫芬尼根有限责任公司 | Interlaced Y multipole |
| CN202977359U (en) * | 2012-11-05 | 2013-06-05 | 聚光科技(杭州)股份有限公司 | Multi-channel mixing ionization source |
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2012
- 2012-11-05 CN CN2012104345261A patent/CN102969218A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB803168A (en) * | 1956-01-31 | 1958-10-22 | Atomic Energy Authority Uk | Improvements in or relating to mass spectrometers |
| US3796872A (en) * | 1970-12-18 | 1974-03-12 | Ass Elect Ind | Mass spectrometry |
| US20030155500A1 (en) * | 1999-02-09 | 2003-08-21 | Syage Jack A. | Interfaces for a photoionization mass spectrometer |
| US20070057178A1 (en) * | 2005-09-12 | 2007-03-15 | Mds Inc. | Mass spectrometer multiple device interface for parallel configuration of multiple devices |
| CN102308360A (en) * | 2009-01-12 | 2012-01-04 | 萨莫芬尼根有限责任公司 | Interlaced Y multipole |
| CN202977359U (en) * | 2012-11-05 | 2013-06-05 | 聚光科技(杭州)股份有限公司 | Multi-channel mixing ionization source |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106461621A (en) * | 2014-03-31 | 2017-02-22 | 莱克公司 | Gc-tof ms with improved detection limit |
| CN108780071A (en) * | 2016-03-07 | 2018-11-09 | 株式会社岛津制作所 | Gaschromatographic mass spectrometric analysis device |
| CN107359100A (en) * | 2017-06-28 | 2017-11-17 | 武汉华星光电技术有限公司 | A kind of ion implantation apparatus and its application method |
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Application publication date: 20130313 |