CN102940982B - High-efficiency defoaming agent for biological fermentation system and preparation process thereof - Google Patents
High-efficiency defoaming agent for biological fermentation system and preparation process thereof Download PDFInfo
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Abstract
The invention relates to a high-efficiency defoaming agent for a biological fermentation system and a preparation process of the high-efficiency defoaming agent. The high-efficiency defoaming agent comprises 15-25 parts of organopolysiloxane, 0.5-3 parts of hydrophobic gaseous phase white carbon black, 5-15 parts of polyether modified silicone oil, 0.2-2 parts of silicon resin, 4-10 parts of a food-grade emulsifier, 0.2-2 parts of a food-grade dispersing thickening agent, 0.2-2 parts of a sodium hydroxide solution with the mass concentration of 10% and 40-80 parts of deionized water. The preparation process of the defoaming agent comprises that the organopolysiloxane, the hydrophobic gaseous phase white carbon black and the silicon resin are subjected to high-temperature bonding. If the viscosity of the organopolysiloxane is lower than 20000CST, a method for adding the emulsifier in an aqueous phase can be used, a method for adding the emulsifier in an oil phase can also be used, and if the viscosity of the organopolysiloxane is higher than 20000CST, the method for adding the emulsifier in an oil phase can be used for preparing the defoaming agent. The defoaming agent is fast in defoaming speed and high in foam inhibition ability. The defoaming agent is particularly excellent in terms of defoaming and foam inhibition effects in the microbial fermentation system, and no side effect is produced for production.
Description
Technical field
The present invention relates to a kind of defoamer, particularly a kind of high effective antifoaming agent for biofermentation system and preparation method thereof.Belong to chemical technology field.
Background technology
Microbial fermentation system is a typical aqueous based systems, and during the fermentation, owing to will supplement a large amount of aseptic fresh air to promote thalli growth, wind supply quantity increases, and therefore can produce a large amount of foam, fermentation tank is also usually full of by foam.The existence of a large amount of foam not only can make the actual volume available in fermentation tank greatly reduce, and causes nutrient solution to overflow from fermentation tank, and can affect the metabolic processes of microorganism, and make product uneven.Therefore, the harm eliminating these foams is very important.The conventional method of these foams is suppressed to be add polyether antifoam agent or silicone defoaming agent, but independent use polyether antifoam agent or organosilyl defoamer, often can not have instant froth breaking simultaneously concurrently and press down bubble persistence double properties.Therefore the producer had sells after silicone defoaming agent and polyether antifoam agent mixing, to obtaining good resultant effect, but only two kinds of defoamers are simply mixed, not only combination property is still not ideal enough, and this defoamer stability often has problems, the generation of the phenomenons such as layering can be caused, Different periods antifoam content and the uneven situation of performance during interpolation, can be caused.
Summary of the invention
The object of the invention is: have excellent defoaming effect concurrently for microbial fermentation system provides a kind of and press down bubble persistent high effective antifoaming agent for biofermentation system and preparation method thereof, to it solve in sweat due to ventilation, stir the uneven problem of the practical volume minimizing of the fermentation tank caused, foam overflow, product quality.High effective antifoaming agent of the present invention has good antifoaming performance, is a kind of aqueous based systems defoamer efficiently.
The present invention realizes by the following technical solutions: a kind of high effective antifoaming agent for biofermentation system, it is characterized in that it is made up of by following mass parts following component: organopolysiloxane is 15-25 part, hydrophobic gas-phase silica is 0.5-3 part, polyether modified silicon oil is 5-15 part, silicones is 0.2-2 part, food grade emulsifier is 4-10 part, food-grade dispersion thickener is 0.2-2 part, mass concentration be 10% sodium hydroxide solution be 0.2-2 part and deionized water is 40-80 part.
Described organopolysiloxane, what its silica chain was connected with silicon atom can be various forms of alkyl or hydroxyl, generally selects the alkyl be connected with silicon atom to be methyl, and selects the dimethicone of trimethyl end-blocking or hydroxy-end capped dimethicone.
Described hydrophobic gas-phase silica, is through the hydrophily white carbon of hydrophobic treatment.
Described silicones is MQ type silicones.
Described food grade emulsifier comprises non-ionic surface active agent, anion surfactant, and its HLB value selects 7.0-10.5.
Described food-grade dispersion thickener can be natural food-grade dispersion thickener, also can be the food-grade dispersion thickener of synthesis.
For a high effective antifoaming agent for biofermentation system, its preparation method comprises the following steps:
1) raw material is taken by following mass parts:
Get that organopolysiloxane is 15-25 part, hydrophobic gas-phase silica is 0.5-3 part, polyether modified silicon oil is 5-15 part, silicones is 0.2-2 part, food grade emulsifier is 4-10 part, food-grade dispersion thickener is 0.2-2 part, mass concentration be 10% sodium hydroxide solution be 0.2-2 part and deionized water is 40-80 part;
2) organopolysiloxane of above-mentioned mass parts, hydrophobic gas-phase silica and silicones are added in electrical heating tank, at being warming up to 180-240 DEG C, maintaining and stir 1-3 hour, obtain silicon cream;
3) high effective antifoaming agent for the preparation of biofermentation system both can adopt emulsifying agent to add Aqueous phase, and emulsifying agent also can be adopted to add oil phase method; Organopolysiloxane viscosity, at below 20000CST, both can adopt emulsifying agent to be added in Aqueous phase, and emulsifying agent also can be adopted to be added in oil phase method, and organopolysiloxane viscosity be at more than 20000CST, then adopt emulsifying agent to add oil phase legal system standby;
Emulsifying agent is adopted to add Aqueous phase:
3-1) disperse thickener to stir at 50-60 DEG C the food-grade of the deionized water of above-mentioned mass parts and above-mentioned mass parts to melt, the mass concentration adding above-mentioned mass parts is 10% sodium hydroxide solution temperature rise to 75 DEG C, adds being uniformly mixed of the food grade emulsifier of above-mentioned mass parts;
3-2) the silicon cream of step 2 and the polyether modified silicon oil of above-mentioned mass parts are joined step 3-1) in mixture at the emulsified stirring 1-3 hour of temperature 75 DEG C, obtain emulsion;
3-3) emulsion is carried out high shear homogeneous or colloid mill homogeneous 0.5-1.5 hour at lower than 55 DEG C of temperature, obtain finished product;
Emulsifying agent is adopted to add oil phase method:
3-a) polyether modified silicon oil of step 2 silicon cream, above-mentioned mass parts and food grade emulsifier are uniformly mixed 1-3 hour at 75 DEG C of temperature;
3-b) add in the mixture of step 3-a and stir 1-3 hour by accounting for above-mentioned mass parts 1/3-1/2 deionized water 75 DEG C of emulsifications, obtain emulsion;
3-c) emulsion is carried out high shear homogeneous or colloid mill homogeneous 0.5-1.5 hour at lower than 55 DEG C of temperature, make emulsion particle diameter be in 2-30um;
3-d) food-grade of above-mentioned mass parts dispersion thickener is dissolved in remaining deionized water for stirring at 50-60 DEG C to melt, the mass concentration adding above-mentioned mass parts is that 10% NaOH stirs, and obtains viscous water;
3-e) viscous water is slowly added in the emulsion of step 3-c under stirring, maintain and stir 20-30 minute, until mix; Obtain finished product.
Described non-ionic surface active agent is this dish, tween, brij72 emulsifying agent or brij721 emulsifying agent; Anion surfactant is lauryl sodium sulfate; HLB value selects 7.0-10.5.
Described natural food-grade dispersion thickener is sodium alginate, and the food-grade dispersion thickener of synthesis is as xanthan gum or carboxymethyl cellulose.
The preparation method of described polyether modified silicon oil is: with the containing hydrogen silicone oil of hydrogeneous base mass percent 0.2-2.0%, the polyethers that the mass percent 30% that containing hydrogen silicone oil accounts for reaction raw materials is polymerized with the double bond containing polyoxyethylene of end group, oxypropylene block, polyethers accounts for the mass percent 70% of reaction raw materials, above-mentioned raw materials is added in flask, be warming up to 60 degree, the platinum chloric acid or the trifluoroacetic acid that add the quality 100ppm accounting for reaction raw materials carry out catalysis, then at 100-120 degree temperature, through hydrosilylation, 4-5 hour and obtain;
Described polyether modified silicon oil also can directly be bought, the key technical indexes: outward appearance light yellow clear oily liquids; Temperature is 25 DEG C time, and density is 1.03 g/cm
3; Viscosity is 1500 ~ 4000CS; Cloud point is 47 DEG C; Effective ingredient>=99.5%.
The invention has the beneficial effects as follows: technology of the present invention compared with prior art, this high effective antifoaming agent for biofermentation system of the present invention, from the composition design of active material and in preparation method, the aspects factors such as the rapidity of its froth breaking, the persistence pressing down bubble and emulsion intercalation method are all taken into full account.And make each factor obtain splendid combination.Defoamer obtained by the present invention has good effect in most of water-based system.Especially in microbial fermentation system, not only can eliminate rapidly due to ventilation, stir the foam caused, the also generation again of sustainable inhibition system foam in whole production process.Froth breaking, press down bubble effect all very excellent.
Detailed description of the invention
Clearly the present invention is described further below by the specific embodiment provided, but not as a limitation of the invention.
embodiment 1
For a high effective antifoaming agent for biofermentation system, its preparation method comprises the following steps:
1) raw material is taken by following mass parts:
Get that organopolysiloxane is 15kg, hydrophobic gas-phase silica is 0.5 kg, polyether modified silicon oil is 5 kg, silicones is 0.2 kg, food grade emulsifier is 4 kg, food-grade dispersion thickener is 0.2 kg, mass concentration be 10% sodium hydroxide solution be 0.2 kg and deionized water is 40 kg;
2) the hydrophobic gas-phase silica of the organopolysiloxane of 15kg, 0.5 kg and 0.2 silicones are added in electrical heating tank, at being warming up to 180-240 DEG C, maintaining and stir 1-3 hour, obtain silicon cream;
3) organopolysiloxane viscosity is at below 20000CST, adopts emulsifying agent to be added in Aqueous phase, emulsifying agent also can be adopted to be added in oil phase method,
The present embodiment adopts emulsifying agent to add Aqueous phase:
3-1) disperse thickener to stir at 50-60 DEG C 40 kg deionized waters and 0.2 kg food-grade to melt, the mass concentration adding 0.2 kg is 10% sodium hydroxide solution temperature rise to 75 DEG C, adds being uniformly mixed of the food grade emulsifier of 4 kg;
3-2) the silicon cream of step 2 and the polyether modified silicon oil of 5 kg are joined step 3-1) in mixture at the emulsified stirring 1-3 hour of temperature 75 DEG C, obtain emulsion;
3-3) emulsion is carried out high shear homogeneous or colloid mill homogeneous 0.5-1.5 hour at lower than 55 DEG C of temperature, obtain finished product;
Described organopolysiloxane, what its silica chain was connected with silicon atom is various forms of alkyl or hydroxyl, selects the dimethicone of trimethyl end-blocking or hydroxy-end capped dimethicone.Described hydrophobic gas-phase silica, is through the hydrophily white carbon of hydrophobic treatment.During hydrophobic treatment, HDMS, DMC class material selected by water-repelling agent, selects white carbon specific area at 150-300M
2/ g.
Described silicones is MQ type silicones.MQ type silicones closes by four degree of functionality siloxane polycondensation chain links and single functionality siloxanes the extraordinary silicones of a class that chain link forms.The molal weight of MQ type silicones is generally 1000 ~ 8000g/mol.The properties and applications scope of mole when structures shape resin of M chain link of the M chain link in molecular structure.The ratio selecting n (M)/n (Q) in MQ silicones is 0.1-1.0.
Described food-grade dispersion thickener is sodium alginate; Described food grade emulsifier is this dish, and it belongs to non-ionic surface active agent.
The preparation method of described polyether modified silicon oil is: be the containing hydrogen silicone oil of 0.2-2.0% with hydrogeneous base mass percent, the polyethers that the mass percent 30% that containing hydrogen silicone oil accounts for reaction raw materials is polymerized with the double bond containing polyoxyethylene of end group, oxypropylene block, the mass percent 70% that polyethers accounts for reaction raw materials is reacted, method adds in flask by above-mentioned raw materials, be warming up to 60 degree, the platinum chloric acid or the trifluoroacetic acid that add the quality 100ppm accounting for reaction raw materials carry out catalysis, then at 100-120 degree temperature, through hydrosilylation, 4-5 hour and obtain.
embodiment 2
Substantially identical with embodiment 1, difference is: organopolysiloxane is 25kg, hydrophobic gas-phase silica is 3kg, polyether modified silicon oil is 15kg, silicones is 2kg, food grade emulsifier is 10kg, food-grade dispersion thickener is 2kg, mass concentration be 10% sodium hydroxide solution be 2kg and deionized water is 80kg.Described food-grade dispersion thickener is xanthan gum; Described food grade emulsifier is tween, and it belongs to non-ionic surface active agent.
Described polyether modified silicon oil purchased from Qingdao industrial organosilicon new material Co., Ltd, address: economic development zone, Laixi, Qingdao City Zhujiang River road phone 86-0532-88431918.Described polyether modified silicon oil the key technical indexes: outward appearance light yellow clear oily liquids; Temperature is 25 DEG C time, and density is 1.03 g/cm
3; Viscosity is 1500 ~ 4000CS; Cloud point is 47 DEG C; Effective ingredient>=99.5%.
embodiment 3
Substantially identical with embodiment 1, difference is: organopolysiloxane is 20kg, hydrophobic gas-phase silica is 1.5kg, polyether modified silicon oil is 10kg, silicones is 1kg, food grade emulsifier is 8kg, food-grade dispersion thickener is 1kg, mass concentration be 10% sodium hydroxide solution be 1.2kg and deionized water is 50kg.Described food-grade dispersion thickener is carboxymethyl cellulose; Described food grade emulsifier is lauryl sodium sulfate, and it belongs to anion surfactant.
Described organopolysiloxane viscosity at more than 20000CST, then adopts emulsifying agent to add oil phase legal system standby:
3-a) polyether modified silicon oil of step 2 silicon cream, 10kg and 8kg food grade emulsifier are uniformly mixed 1-3 hour at 75 DEG C of temperature;
3-b) 25kg deionized water is added in the mixture of step 3-a and stir 1-3 hour 75 DEG C of emulsifications, obtain emulsion; The consumption of deionized water: removing ionized water total amount 1/3-1/2 can;
3-c) emulsion is carried out high shear homogeneous or colloid mill homogeneous 0.5-1.5 hour at lower than 55 DEG C of temperature, make emulsion particle diameter be in 2-30um;
3-d) 1kg food-grade dispersion thickener is dissolved in remaining 25kg deionized water for stirring at 50-60 DEG C to melt, the mass concentration adding 1.2kg is that 10% NaOH stirs, and obtains viscous water;
3-e) viscous water is slowly added in the emulsion of step 3-c under stirring, maintain and stir 20-30 minute, until mix; Obtain finished product.
embodiment 4
1, raw material is taken by following formula: get 1000CST dimethyl silicone polymer 232.5KG;
Getting specific area is 200M
2the hydrophobic gas-phase silica 12.5KG of/g; The ratio getting n (M)/n (Q) is 0.8 silicones 5KG; Get polyether modified silicon oil 80KG (polyether modified silicon oil can obtain in advance by the method introduced in foregoing summary, also commercially can choose the polyether modified silicon oil commodity met the demands); Get span60 33.8KG altogether; Tween60 is 16.2KG altogether; Get RHODICARE H food thickening agent 0.8KG; Get 10% NaOH 1.3KG; Remove ionized water 619.1KG.
2, the preparation method of this defoamer comprises the following steps: (this example adopts emulsifying agent to be added in Aqueous phase)
1) preparation of silicon cream: add in electrical heating tank by the dimethyl silicone polymer of above-mentioned mass parts, hydrophobic gas-phase silica, MQ silicones, be warming up to 200 DEG C, maintains and stirs 2-3 hour, make silicon cream.(MQ silicones also can be down to about 140-150 DEG C and add by equitemperature, and silicon cream color and luster obtained is like this better).
2) deionized water of above-mentioned mass parts, food thickening agent RHODICARE H are added in still to stir at 50-60 DEG C melt.Add 10% sodium hydroxide solution, by still temperature rise to 75 DEG C, add emulsifying agent span60 and tween60 of above-mentioned mass parts, stir.Add silicon cream prepared by step 1) again, carry out fully emulsified 1-3 hour.
3) by step 2) emulsion prepared imports high shear homogeneous still homogeneous 15-20 minute.Then check, weigh, pack, obtained defoamer of the present invention.
embodiment 5
1, raw material is taken by following formula: get 5000CST dimethyl silicone polymer 232.5KG;
Getting specific area is 200M
2the hydrophobic gas-phase silica 10KG of/g; The ratio getting n (M)/n (Q) is 0.8 silicones 7.5KG; Get polyether modified silicon oil 90KG (polyether modified silicon oil can obtain in advance by the method introduced in foregoing summary, also commercially can choose the polyether modified silicon oil commodity met the demands); Get span60 33.8KG altogether; Tween60 is 16.2KG altogether; Get RHODICARE H food thickening agent 0.8KG; Get 10% NaOH 1.3KG; Remove ionized water 607.9KG.
2, preparation method adopts emulsifying agent to be added in Aqueous phase with embodiment 4(the present embodiment).
embodiment 6
1, raw material is taken by following formula: get 10000CST dimethyl silicone polymer 211.6KG;
Getting specific area is 200M
2the hydrophobic gas-phase silica 11.5KG of/g; The ratio getting n (M)/n (Q) is 0.8 silicones 6.9KG; Get polyether modified silicon oil 90KG (polyether modified silicon oil can obtain in advance by the method introduced in foregoing summary, also commercially can choose the polyether modified silicon oil commodity met the demands); Get span60 40.6KG altogether; Tween60 is 19.4KG altogether; Get RHODICARE H food thickening agent 0.8KG; Get 10% NaOH 1.3KG; Remove ionized water 617.9KG.
2, preparation method adopts emulsifying agent to be added in Aqueous phase with embodiment 4(the present embodiment).
embodiment 7
1, raw material is taken by following formula: get 30000CST dimethyl silicone polymer 180.4KG; Get 500CST dimethyl silicone polymer 22KG; Getting specific area is 200M
2the hydrophobic gas-phase silica 13.2KG of/g; The ratio getting n (M)/n (Q) is 0.8 silicones 4.4KG; Get polyether modified silicon oil 100KG (polyether modified silicon oil can obtain in advance by the method introduced in foregoing summary, also commercially can choose the polyether modified silicon oil commodity met the demands); Get span60 41.7KG altogether; Get Brij721 18.3KG altogether; Get RHODICARE H food thickening agent 0.8KG; Get 10% NaOH 1.3KG; Remove ionized water 617.9KG.
2, the preparation method of this defoamer comprises the following steps: (this example adopts emulsifying agent to be added in oil phase method)
1) preparation of silicon cream: add in electrical heating tank by the dimethyl silicone polymer of above-mentioned mass parts, hydrophobic gas-phase silica, MQ silicones, be warming up to 220 DEG C, maintains and stirs 2-3 hour, make silicon cream.(MQ silicones also can be down to about 140-150 DEG C and add by equitemperature, and silicon cream color and luster obtained is like this better).
2) the silicon cream prepared by step 1) and emulsifying agent, the polyether modified silicon oil of above-mentioned mass parts
Add reactor, be warming up to 75 DEG C and carry out stirring and emulsifying 1-3 hour.Then slowly add emulsified water (emulsified water accounts for 30 parts of defoamer mass parts), 1-2 hour is stirred in emulsification.Be cooled to about 55 DEG C, cross colloid mill homogeneous, make emulsion particle diameter be in 2-30um.
3) preparing viscous water in advance (is dissolved in when 50-60 DEG C in residue water by the food thickening agent of above-mentioned mass parts, add 10% NaOH emulsion of above-mentioned mass parts, stir), and viscous water is slowly added in the emulsion of colloid mill homogeneous under stirring, maintain and stir 20-30 minute, until mix.Then check, weigh, pack, obtained defoamer of the present invention.
embodiment 8
1, raw material is taken by following formula: get 50000CST dimethyl silicone polymer 160KG; Get 1000CST dimethyl silicone polymer 24KG; Getting specific area is 200M
2the hydrophobic gas-phase silica 10KG of/g; The ratio getting n (M)/n (Q) is 0.8 silicones 6KG; Get polyether modified silicon oil 100KG (polyether modified silicon oil can obtain in advance by the method introduced in foregoing summary, also commercially can choose the polyether modified silicon oil commodity met the demands); Get span60 45.1KG altogether; Get Brij721 19.9KG altogether; Get RHODICARE H food thickening agent 0.8KG; Get 10% NaOH 1.3KG; Remove ionized water 632.9KG.
2, preparation method adopts emulsifying agent to be added in oil phase method with this example of embodiment 7().
embodiment 9
1, raw material is taken by following formula: get 60000CST dimethyl silicone polymer 150KG; Get 350CST dimethyl silicone polymer 34KG; Getting specific area is 200M
2the hydrophobic gas-phase silica 11KG of/g; The ratio getting n (M)/n (Q) is 0.8 silicones 5KG; Get polyether modified silicon oil 110KG (polyether modified silicon oil can obtain in advance by the method introduced in foregoing summary, also commercially can choose the polyether modified silicon oil commodity met the demands); Get Brij72 46KG altogether; Get Brij721 19KG altogether; Get RHODICARE H food thickening agent 0.8KG; Get 10% NaOH 1.3KG; Remove ionized water 622.9KG.
2, preparation method adopts emulsifying agent to be added in oil phase method with this example of embodiment 7().
embodiment 10
1, raw material is taken by following formula: get 100000CST dimethyl silicone polymer 126KG; Get 500CST dimethyl silicone polymer 39.6KG; Getting specific area is 200M
2the hydrophobic gas-phase silica 9KG of/g; The ratio getting n (M)/n (Q) is 0.8 silicones 5.4KG; Get polyether modified silicon oil 120KG (polyether modified silicon oil can obtain in advance by the method introduced in foregoing summary, also commercially can choose the polyether modified silicon oil commodity met the demands); Get span60 48.6KG altogether; Get Brij721 21.4KG altogether; Get RHODICARE H food thickening agent 0.8KG; Get 10% NaOH 1.3KG; Remove ionized water 627.9KG.
2, preparation method adopts emulsifying agent to be added in oil phase method with this example of embodiment 7().
embodiment 11
1, raw material is taken by following formula: get 100000CST dimethyl silicone polymer 126KG; Get 1000CST dimethyl silicone polymer 39.6KG; Getting specific area is 200M
2the hydrophobic gas-phase silica 9KG of/g; The ratio getting n (M)/n (Q) is 0.8 silicones 5.4KG; Get polyether modified silicon oil 120KG (polyether modified silicon oil can obtain in advance by the method introduced in foregoing summary, also commercially can choose the polyether modified silicon oil commodity met the demands); Get Brij72 49.5KG altogether; Get Brij721 20.5KG altogether; Get RHODICARE H food thickening agent 0.8KG; Get 10% NaOH 1.3KG; Remove ionized water 627.9KG.
2, preparation method adopts emulsifying agent to be added in oil phase method with this example of embodiment 7().
Raw materials market in above-described embodiment is all on sale, wherein:
Dimethyl silicone polymer (dimethicone) the Dow corning company of all size produces, and available from NCM;
Emulsifying agent span60(Si coils), emulsifying agent tween60 (tween): Jiangsu Hai'an Petrochemical Plant produce, this factory factory site: No. 28, Hai Hua road, county town, Hai'an, Jiangsu Province, postcode: 226600;
Hydrophobic gas-phase silica: Shenyang Chemical Manufacture;
MQ silicones: Shandong Dayi Chemical Industry Co., Ltd produces;
RHODICARE H(xanthan gum) food thickening agent: French sieve ground is sub-to be produced, and available from Guangzhou Chen Qian Chemical Co., Ltd.;
Emulsifying agent Brij72 [polyoxyethylene (2) stearyl ether], Brij721 [polyoxyethylene (21) stearyl ether]: Kening Co., Ltd produces, and available from Guangzhou Qi Sheng company.
effect assessment test of the present invention and result
Foaming system: with (80-90 DEG C maintains 30 minutes) 10% dregs of beans filtrate under high temperature as foaming system.
Defoamer: the finished product adopting embodiment 1-11.
Froth breaking, press down bubble effect evaluation method: in 500ml graduated cylinder, add 100ml expanding foam solution, then with 50L/h speed by the air-blowing head that is covered with micropore from air-blowing bottom graduated cylinder, when foam reaches 500ml, add 0.01g defoamer wherein, observe its defoaming effect; In ventilation after 10 minutes, measure the amount of foam, as the Appreciation gist of suds suppressing properties.
| Embodiment | Defoaming effect | Press down bubble effect (foam volume, ml) |
| Blank | Not froth breaking | 755 |
| GPE | 80s | 420 |
| 1 | 58s | 310 |
| 2 | 43s | 285 |
| 3 | 51s | 299 |
| 4 | 48s | 295 |
| 5 | 31s | 270 |
| 6 | 25s | 250 |
| 7 | 19s | 230 |
| 8 | 16s | 210 |
| 9 | 13s | 210 |
| 10 | 9s | 200 |
| 11 | 7s | 200 |
Find out from upper table, embodiment 1-embodiment 11 all has good froth breaking, presses down bubble effect, and along with the increase of polysiloxane molecule amount, its froth breaking, presses down bubble better effects if.
Claims (7)
1. for a high effective antifoaming agent for biofermentation system, it is characterized in that it is made up of by following mass parts following component: organopolysiloxane is 15-25 part, hydrophobic gas-phase silica is 0.5-3 part, polyether modified silicon oil is 5-15 part, silicones is 0.2-2 part, food grade emulsifier is 4-10 part, food-grade dispersion thickener is 0.2-2 part, mass concentration be 10% sodium hydroxide solution be 0.2-2 part and deionized water is 40-80 part;
This preparation method being used for the high effective antifoaming agent of biofermentation system comprises the following steps:
1) raw material is taken by following mass parts:
Get that organopolysiloxane is 15-25 part, hydrophobic gas-phase silica is 0.5-3 part, polyether modified silicon oil is 5-15 part, silicones is 0.2-2 part, food grade emulsifier is 4-10 part, food-grade dispersion thickener is 0.2-2 part, mass concentration be 10% sodium hydroxide solution be 0.2-2 part and deionized water is 40-80 part;
2) organopolysiloxane of above-mentioned mass parts, hydrophobic gas-phase silica and silicones are added in electrical heating tank, at being warming up to 180-240 DEG C, maintaining and stir 1-3 hour, obtain silicon cream;
3) high effective antifoaming agent for the preparation of biofermentation system adopts emulsifying agent to add Aqueous phase or adopts emulsifying agent to add oil phase method; Organopolysiloxane viscosity is at below 20000CST, and adopt emulsifying agent to be added in Aqueous phase or adopt emulsifying agent to be added in oil phase method, and organopolysiloxane viscosity is at more than 20000CST, then adopt emulsifying agent to add oil phase legal system standby;
Emulsifying agent is adopted to add Aqueous phase:
3-1) disperse thickener to stir at 50-60 DEG C the food-grade of the deionized water of above-mentioned mass parts and above-mentioned mass parts to melt, the mass concentration adding above-mentioned mass parts is 10% sodium hydroxide solution temperature rise to 75 DEG C, adds being uniformly mixed of the food grade emulsifier of above-mentioned mass parts;
3-2) the silicon cream of step 2 and the polyether modified silicon oil of above-mentioned mass parts are joined step 3-1) in mixture at the emulsified stirring 1-3 hour of temperature 75 DEG C, obtain emulsion;
3-3) emulsion is carried out high shear homogeneous or colloid mill homogeneous 0.5-1.5 hour at lower than 55 DEG C of temperature, obtain finished product;
Emulsifying agent is adopted to add oil phase method:
3-a) polyether modified silicon oil of step 2 silicon cream, above-mentioned mass parts and food grade emulsifier are uniformly mixed 1-3 hour at 75 DEG C of temperature;
3-b) add in the mixture of step 3-a and stir 1-3 hour by accounting for above-mentioned mass parts 1/3-1/2 deionized water 75 DEG C of emulsifications, obtain emulsion;
3-c) emulsion is carried out high shear homogeneous or colloid mill homogeneous 0.5-1.5 hour at lower than 55 DEG C of temperature, make emulsion particle diameter be in 2-30um;
3-d) food-grade of above-mentioned mass parts dispersion thickener is dissolved in remaining deionized water for stirring at 50-60 DEG C to melt, the mass concentration adding above-mentioned mass parts is that 10% NaOH stirs, and obtains viscous water;
3-e) viscous water is slowly added in the emulsion of step 3-c under stirring, maintain and stir 20-30 minute, until mix; Obtain finished product.
2. a kind of high effective antifoaming agent for biofermentation system according to claim 1, is characterized in that: described silicones is MQ type silicones.
3. a kind of high effective antifoaming agent for biofermentation system according to claim 1, it is characterized in that: described food grade emulsifier comprises non-ionic surface active agent, anion surfactant, its HLB value selects 7.0-10.5.
4. a kind of biofermentation system high effective antifoaming agent according to claim 1, is characterized in that: described food-grade dispersion thickener is natural food-grade dispersion thickener, or the food-grade dispersion thickener of synthesis.
5. a kind of high effective antifoaming agent for biofermentation system according to claim 3, is characterized in that: described non-ionic surface active agent is this dish or tween; Anion surfactant is lauryl sodium sulfate; HLB value selects 7.0-10.5.
6. a kind of biofermentation system high effective antifoaming agent according to claim 4, is characterized in that: described natural food-grade dispersion thickener is sodium alginate, and the food-grade dispersion thickener of synthesis is xanthan gum or carboxymethyl cellulose.
7. a kind of biofermentation system high effective antifoaming agent according to claim 1, it is characterized in that: the preparation method of described polyether modified silicon oil is: be the containing hydrogen silicone oil of 0.2-2.0% with hydrogeneous base mass percent, containing hydrogen silicone oil accounts for mass percent 30% and the double bond containing polyoxyethylene of end group of reaction raw materials, the polyethers of oxypropylene block polymerization, polyethers accounts for the mass percent 70% of reaction raw materials, above-mentioned raw materials is added in flask, be warming up to 60 degree, the platinum chloric acid or the trifluoroacetic acid that add the quality 100ppm accounting for reaction raw materials carry out catalysis, then at 100-120 degree temperature, through hydrosilylation, 4-5 hour and obtain, or the polyether modified silicon oil directly bought, the key technical indexes: outward appearance light yellow clear oily liquids, temperature is 25 DEG C time, and density is 1.03 g/cm
3, viscosity is 1500 ~ 4000CS, cloud point is 47 DEG C, effective ingredient>=99.5%.
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| CN104069654A (en) * | 2014-07-01 | 2014-10-01 | 西安道尔达化工有限公司 | Preparation method of high-viscosity organic silicon defoamer |
| CN104492127A (en) * | 2014-12-04 | 2015-04-08 | 宿州市华润化工有限责任公司 | Method for preparing preservative-free organic silicone defoamer |
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| CN107982963B (en) * | 2017-12-07 | 2020-05-05 | 广州旭太材料科技有限公司 | Modified organic silicon defoaming agent, defoaming agent composition and preparation method thereof |
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| CN110681187A (en) * | 2019-10-28 | 2020-01-14 | 上海保立佳新材料有限公司 | Defoaming agent |
| CN110964755B (en) * | 2019-12-06 | 2020-11-20 | 鹤山市东古调味食品有限公司 | Method for treating foam in microbial fermentation process |
| CN111151033A (en) * | 2020-01-17 | 2020-05-15 | 广东轻工职业技术学院 | Preparation method of novel polyether modified organic silicon defoaming agent |
| CN112376319B (en) * | 2020-10-29 | 2021-06-15 | 江苏利宏科技发展有限公司 | Defoaming agent for papermaking and preparation method thereof |
| CN112774260B (en) * | 2020-12-17 | 2022-08-02 | 新疆水处理工程技术研究中心有限公司 | Polyether defoaming agent and preparation method thereof |
| CN113308188A (en) * | 2021-04-22 | 2021-08-27 | 浙江新安化工集团股份有限公司 | Organic silicon dispersion and preparation method and application thereof |
| CN113368543A (en) * | 2021-06-11 | 2021-09-10 | 江苏赛欧信越消泡剂有限公司 | Organic silicon polyether emulsion type defoaming agent and preparation method and application thereof |
| CN114699805A (en) * | 2021-12-31 | 2022-07-05 | 宁夏顺邦达新材料有限公司 | Defoaming agent for suspension process polyvinyl chloride production process and preparation method thereof |
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