CN102920470B - The medical image system that bimodulus merges and method - Google Patents

The medical image system that bimodulus merges and method Download PDF

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CN102920470B
CN102920470B CN201210397429.XA CN201210397429A CN102920470B CN 102920470 B CN102920470 B CN 102920470B CN 201210397429 A CN201210397429 A CN 201210397429A CN 102920470 B CN102920470 B CN 102920470B
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蒯多杰
张涛
郑健
刘岿
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Suzhou Institute of Biomedical Engineering and Technology of CAS
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Abstract

一种双模融合的医学成像系统,包括:机架单元;第一显像单元;第二显像单元,第一显像单元与第二显像单元前后并列固定设置于机架单元上,第一显像单元的成像中心点与第二显像单元成像中心点处于同一水平线上;控制单元,电性连接于第一显像单元和第二显像单元,用于控制第一显像单元生成第一图像信息及第二显像单元生成第二图像信息;图像单元,电性连接于第一显像单元和第二显像单元,用于对第一图像信息及第二图像信息进行重建、配准及融合;诊断床单元,电性连接于控制单元,受控制单元控制实现水平移动及升降运动。本发明还提供了一种双模融合的医学成像方法。本发明提供的双模融合的医学成像系统提升了图像配准精度,改善了图像融合质量。

A medical imaging system with dual-mode fusion, comprising: a rack unit; a first imaging unit; a second imaging unit, the first imaging unit and the second imaging unit are arranged side by side on the rack unit, and the second The imaging central point of the first imaging unit and the imaging central point of the second imaging unit are on the same horizontal line; the control unit is electrically connected to the first imaging unit and the second imaging unit, and is used to control the first imaging unit to generate The first image information and the second display unit generate second image information; the image unit is electrically connected to the first display unit and the second display unit, and is used to reconstruct the first image information and the second image information, Registration and fusion; the diagnostic bed unit is electrically connected to the control unit, and is controlled by the control unit to realize horizontal movement and lifting movement. The invention also provides a dual-mode fusion medical imaging method. The dual-mode fusion medical imaging system provided by the present invention improves image registration precision and improves image fusion quality.

Description

双模融合的医学成像系统及方法Dual-modal fusion medical imaging system and method

技术领域 technical field

本发明涉及一种医学成像领域,尤其涉及一种双模融合的医学成像系统及方法。The invention relates to the field of medical imaging, in particular to a dual-mode fusion medical imaging system and method.

背景技术 Background technique

正电子核素显像技术(PET)可以提供人体新陈代谢的功能图像,但是PET信噪比和空间分辨率都很低,PET图像显示的病变的高代谢区域很难进行精确的定位,而X射线断层显像(CT)技术成像清晰、空间分辨率较高,可为病灶的定位取到良好的参照作用,但是其对病灶本身的显示作用却比较差。因此可以将PET图像和CT图像进行融合,实现更佳的成像效果。Positron tomography (PET) can provide functional images of human metabolism, but the signal-to-noise ratio and spatial resolution of PET are very low. Tomographic imaging (CT) technology has clear images and high spatial resolution, which can provide a good reference for the location of lesions, but its display effect on lesions itself is relatively poor. Therefore, PET images and CT images can be fused to achieve better imaging effects.

目前在医学图像融合领域,受限于设备制造及使用,绝大部分进行融合的图像是异机获取的。这种异机获取的图像不可能同步采集,并且二者的采集坐标系也很难进行统一,这样不同成像模式的图像配准精度不高,影响了融合后图像的质量。At present, in the field of medical image fusion, most of the images to be fused are obtained from different machines due to limitations in equipment manufacturing and use. The images acquired by different machines cannot be acquired synchronously, and it is difficult to unify the acquisition coordinate systems of the two, so the image registration accuracy of different imaging modes is not high, which affects the quality of the fused image.

发明内容 Contents of the invention

基于此,有必要针对上述融合式医学图像存在的缺陷,提供一种配准精度较高的双模融合的医学成像系统。Based on this, it is necessary to provide a dual-mode fusion medical imaging system with high registration accuracy for the defects of the above fusion medical images.

一种双模融合的医学成像系统,包括:A dual-mode fusion medical imaging system, comprising:

机架单元,包括:rack unit, including:

底座;base;

第一机架,包括:First rack, including:

第一固定机架,固定于所述底座上;a first fixed frame, fixed on the base;

外圈支撑轴承,包括相互对应的第一定子及第一转子,所述第一定子固定于所述第一固定机架上;The outer ring support bearing includes a first stator and a first rotor corresponding to each other, and the first stator is fixed on the first fixed frame;

旋转机架,所述旋转机架通过所述第一转子设置于所述第一固定机架上;a rotating frame, the rotating frame is arranged on the first fixed frame through the first rotor;

力矩电机,固定连接于所述第一固定机架及所述旋转机架;及a torque motor fixedly connected to the first fixed frame and the rotating frame; and

第一位置传感器,固定连接于所述力矩电机,用于采集所述力矩电机的旋转位置;及a first position sensor, fixedly connected to the torque motor, for collecting the rotational position of the torque motor; and

第二机架,包括第二固定机架,所述第二固定机架固定于所述底座上;The second frame includes a second fixed frame, and the second fixed frame is fixed on the base;

第一显像单元,固定设置于所述第一机架上;The first imaging unit is fixedly arranged on the first frame;

第二显像单元,固定设置于所述第二机架上,所述第二显像单元与所述第一显像单元前后并列设置,且所述第一显像单元的成像中心点与所述第二显像单元成像中心点处于同一水平线上;The second imaging unit is fixedly arranged on the second frame, the second imaging unit is arranged side by side with the first imaging unit, and the imaging center point of the first imaging unit is aligned with the first imaging unit. The imaging central point of the second imaging unit is on the same horizontal line;

控制单元,电性连接于所述第一位置传感器、所述第一显像单元及所述第二显像单元,用于采集所述力矩电机的位置信息、并控制所述第一显像单元生成第一图像信息及所述第二显像单元生成第二图像信息,A control unit, electrically connected to the first position sensor, the first display unit and the second display unit, for collecting the position information of the torque motor and controlling the first display unit generating first image information and said second display unit generating second image information,

图像单元,电性连接于所述第一显像单元和第二显像单元,用于接收所述第一图像信息及所述第二图像信息,并对所述第一图像信息及所述第二图像信息进行重建、配准及融合计算;及An image unit, electrically connected to the first image display unit and the second image display unit, for receiving the first image information and the second image information, and analyzing the first image information and the second image information 2. Image information is reconstructed, registered and fused; and

诊断床单元,电性连接于所述控制单元,受所述控制单元控制实现水平移动及升降运动。The diagnostic bed unit is electrically connected to the control unit, and is controlled by the control unit to realize horizontal movement and lifting movement.

一种双模融合的医学成像方法,包括下述步骤:建立以所述诊断床为基准的坐标;定位所述第一显像单元及定位所述第二显像单元,实现结构配准;所述控制单元控制所述第一显像单元及所述第二显像单元,并分别生成第一图像信息及第二图像信息;其中,所述控制单元在采集所述第一图像信息或所述第二图像信息的同时,并分别采集所述力矩电机及所述诊断床单元的位置信息;基于所述第一图像信息、所述第二图像信息及所述位置信息,重建所述第一图像信息及所述第二图像信息;配准经重建后的所述第一图像信息及所述第二图像信息;融合经配准后的所述第一图像信息及所述第二图像信息。A medical imaging method for dual-mode fusion, comprising the following steps: establishing coordinates based on the diagnostic bed; positioning the first imaging unit and positioning the second imaging unit to achieve structural registration; The control unit controls the first imaging unit and the second imaging unit, and generates first image information and second image information respectively; wherein, the control unit collects the first image information or the Simultaneously with the second image information, respectively collect the position information of the torque motor and the diagnostic bed unit; based on the first image information, the second image information and the position information, reconstruct the first image information and the second image information; registering the reconstructed first image information and the second image information; fusing the registered first image information and the second image information.

上述双模融合的医学成像系统将第一显像单元及第二显像单元精确固定在机架单元上,通过调整第一显像单元及第二显像单元,使得第一显像单元及第二显像单元的成像中心处于同一水平线上,保证了第一显像单元及第二显像单元的图像采集坐标系相统一;同时采用统一的控制单元,优化控制流程,使第一显像单元及第二显像单元的显像时间间隔尽量短,减少受检者身体不自主移位对图像配准造成的影响;然后将采集的第一图像信息及第二图像信息传输至图像单元,并进行图像重建,再对重建后的第一图像信息及第二图像信息进行二次配准,提升了配准精度,大幅改善了后续的图像融合质量。The medical imaging system with dual-mode fusion described above precisely fixes the first imaging unit and the second imaging unit on the frame unit, and adjusts the first imaging unit and the second imaging unit so that the first imaging unit and the second imaging unit The imaging centers of the two imaging units are on the same horizontal line, which ensures that the image acquisition coordinate systems of the first imaging unit and the second imaging unit are unified; at the same time, a unified control unit is adopted to optimize the control process, so that the first imaging unit and the imaging time interval of the second imaging unit as short as possible to reduce the impact of the involuntary body movement of the subject on image registration; then the collected first image information and second image information are transmitted to the image unit, and Image reconstruction is performed, and then secondary registration is performed on the reconstructed first image information and second image information, which improves the registration accuracy and greatly improves the subsequent image fusion quality.

附图说明 Description of drawings

图1为本发明实施例提供的双模融合的医学成像系统的平面示意图。FIG. 1 is a schematic plan view of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

图2为本发明实施例提供的双模融合的医学成像系统的立体结构图。Fig. 2 is a three-dimensional structure diagram of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

图3为本发明实施例提供的双模融合的医学成像系统的立体分解图。Fig. 3 is a three-dimensional exploded view of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

图4为本发明实施例提供的第一机架一侧面的结构示意图。Fig. 4 is a schematic structural diagram of a side of a first rack provided by an embodiment of the present invention.

图5为本发明实施例提供的第一机架一侧面的局部放大的结构示意图。FIG. 5 is a partially enlarged structural schematic diagram of a side surface of a first rack provided by an embodiment of the present invention.

图6为本发明实施例提供的诊断床单元的立体示意图。Fig. 6 is a schematic perspective view of the diagnostic bed unit provided by the embodiment of the present invention.

图7为本发明实施例提供的双模融合的医学成像系统的第一显像单元的结构示意图。FIG. 7 is a schematic structural diagram of a first imaging unit of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

图8为本发明实施例提供的双模融合的医学成像系统的第二显像单元的结构示意图。FIG. 8 is a schematic structural diagram of a second imaging unit of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

图9为本发明实施例提供的第二显像单元的检测器单元的结构示意图。FIG. 9 is a schematic structural diagram of a detector unit of a second imaging unit provided by an embodiment of the present invention.

图10为本发明实施例提供的双模融合的医学成像方法的流程示意图。FIG. 10 is a schematic flowchart of a medical imaging method for dual-mode fusion provided by an embodiment of the present invention.

图11为本发明实施例提供的双模融合的医学成像方法的生成第一图像信息及第二图像信息的流程示意图。FIG. 11 is a schematic flow chart of generating first image information and second image information in a dual-mode fusion medical imaging method provided by an embodiment of the present invention.

图12为本发明实施例提供的配准经重建后的第一图像信息及第二图像信息的流程图。Fig. 12 is a flow chart of registering reconstructed first image information and second image information provided by an embodiment of the present invention.

图13为本发明实施例提供的图像配准的流程图。Fig. 13 is a flowchart of image registration provided by an embodiment of the present invention.

图13a为本发明实施例提供的图像配准部的结构图。Fig. 13a is a structural diagram of an image registration unit provided by an embodiment of the present invention.

图14为本发明实施例提供的融合经配准后的第一图像信息及第二图像信息的流程图。Fig. 14 is a flow chart of fusing registered first image information and second image information provided by an embodiment of the present invention.

具体实施方式 Detailed ways

请参阅图1~图9。双模融合的医学成像系统10包括:机架单元11、第一显像单元12、第二显像单元13、控制单元14、图像单元15及诊断床单元16。Please refer to Figure 1 to Figure 9. The dual-mode fusion medical imaging system 10 includes: a rack unit 11 , a first imaging unit 12 , a second imaging unit 13 , a control unit 14 , an image unit 15 and a diagnostic bed unit 16 .

机架单元11包括底座110、第一机架111、第二机架112及扫描孔113。机架单元11的主体为钢结构,或者其它具有类似强度的合金材料构成,确保机架形变极小。The frame unit 11 includes a base 110 , a first frame 111 , a second frame 112 and a scanning hole 113 . The main body of the frame unit 11 is made of steel structure, or other alloy materials with similar strength, so as to ensure that the deformation of the frame is extremely small.

第一机架111包括第一固定机架1111、外圈支撑轴承1112、旋转机架1113、力矩电机1114及第一位置传感器1115。第一固定机架1111固定于机架单元11底座上。外圈支撑轴承1112包括相互对应的第一定子(图未示)和第一转子(图未示),第一定子固定于第一固定机架1111上。旋转机架1113通过第一转子固定设置于第一固定机架1111上。力矩电机1114固定连接于第一固定机架1111及旋转机架1113,具体地,力矩电机1114包括第二定子11141、第二转子11142及支座11143,第二定子11141的一端固定连接于第一固定机架1111上,第二定子11141的另一端固定安装在支座11143上,第二转子11142固定连接在旋转机架1113上,通过第二定子11141和第二转子11142间的电磁力矩驱动旋转机架1113运转。第一位置传感器1115包括第三定子11151和第三转子11152,第三定子11151与第二定子11141固定连接,第三转子11152与第二转子11142固定连接,第一位置传感器1115通过采集第三定子11151与第三转子11152之间的感应电势间接测量力矩电机1114的旋转位置。The first frame 111 includes a first fixed frame 1111 , an outer ring support bearing 1112 , a rotating frame 1113 , a torque motor 1114 and a first position sensor 1115 . The first fixed frame 1111 is fixed on the base of the frame unit 11 . The outer ring support bearing 1112 includes a first stator (not shown) and a first rotor (not shown) corresponding to each other, and the first stator is fixed on the first fixed frame 1111 . The rotating frame 1113 is fixed on the first fixed frame 1111 through the first rotor. The torque motor 1114 is fixedly connected to the first fixed frame 1111 and the rotating frame 1113. Specifically, the torque motor 1114 includes a second stator 11141, a second rotor 11142 and a support 11143, and one end of the second stator 11141 is fixedly connected to the first On the fixed frame 1111, the other end of the second stator 11141 is fixedly installed on the support 11143, and the second rotor 11142 is fixedly connected to the rotating frame 1113, and the rotation is driven by the electromagnetic torque between the second stator 11141 and the second rotor 11142 Rack 1113 operates. The first position sensor 1115 includes a third stator 11151 and a third rotor 11152, the third stator 11151 is fixedly connected to the second stator 11141, the third rotor 11152 is fixedly connected to the second rotor 11142, and the first position sensor 1115 collects the third stator 1115 The induced potential between 11151 and the third rotor 11152 indirectly measures the rotational position of the torque motor 1114 .

第一固定机架1111为两个,且结构相同,分别对称固定设置于第一机架111两侧。There are two first fixed frames 1111 with the same structure, which are symmetrically and fixedly arranged on both sides of the first frame 111 respectively.

第二机架112包括第二固定机架1121。第二固定机架1121,可移动地固定于机架单元11底座上。第二固定机架1121为两个,且分别对称固定设置于第二机架112两侧。The second frame 112 includes a second fixed frame 1121 . The second fixed frame 1121 is movably fixed on the base of the frame unit 11 . There are two second fixed frames 1121 , which are symmetrically fixed on both sides of the second frame 112 .

扫描孔113位于机架单元11的中间位置,供受检者进出。扫描孔113直径达到700mm以上,以便于各种体型的受检者顺利通过。受检者可以是人体,也可以是动物、体模或者其他类型的受检物体。The scanning hole 113 is located in the middle of the rack unit 11 for the examinee to enter and exit. The diameter of the scanning hole 113 reaches more than 700mm, so that subjects of various shapes can pass through smoothly. The subject may be a human body, or an animal, a phantom or other types of subject.

第一显像单元12固定设置于机架单元11上。具体地,第一显像单元12通过机架单元11的第一固定机架1111固定于机架单元11上,通过调整第一固定机架1111在机架单元11底座上的位置,以改变第一显像单元12在机架单元11的位置。第一显像单元12为X射线断层显像单元。可以理解,通过旋转机架1113的回旋运动,可带动第一显像单元12的显像链部件沿双模融合的医学成像系统10的扫描孔113轴向做回转运动。The first display unit 12 is fixed on the frame unit 11 . Specifically, the first display unit 12 is fixed on the rack unit 11 through the first fixed frame 1111 of the rack unit 11, and by adjusting the position of the first fixed frame 1111 on the base of the rack unit 11, the second A display unit 12 is at the position of the rack unit 11 . The first imaging unit 12 is an X-ray tomographic imaging unit. It can be understood that, through the rotary motion of the rotating frame 1113 , the imaging chain components of the first imaging unit 12 can be driven to rotate along the axis of the scanning hole 113 of the dual-mode fusion medical imaging system 10 .

第二显像单元13固定设置于机架单元11上,且第二显像单元13与第一显像单元12在空间上前后并列设置。具体地,第二显像单元13通过第二固定机架1121设置于机架单元11上,通过调整第二固定机架1121在机架单元11底座上的位置,以改变第二显像单元13在机架单元11的位置。可以理解,通过调整第一显像单元12及第二显像单元13在机架单元11上的位置,使得第一显像单元12及第二显像单元13的成像中心处于同一水平线上,保证了第一显像单元12及第二显像单元13的图像采集坐标系相统一。The second display unit 13 is fixedly disposed on the frame unit 11 , and the second display unit 13 and the first display unit 12 are spaced side by side. Specifically, the second display unit 13 is arranged on the frame unit 11 through the second fixed frame 1121, and by adjusting the position of the second fixed frame 1121 on the base of the frame unit 11, the position of the second display unit 13 can be changed. In rack unit 11 position. It can be understood that by adjusting the positions of the first imaging unit 12 and the second imaging unit 13 on the frame unit 11, the imaging centers of the first imaging unit 12 and the second imaging unit 13 are on the same horizontal line to ensure The image acquisition coordinate systems of the first display unit 12 and the second display unit 13 are unified.

第一显像单元12包括X射线源模块121、X射线检测器模块122、第一电子学模块123、数据传输模块124及滑环模块125。The first imaging unit 12 includes an X-ray source module 121 , an X-ray detector module 122 , a first electronics module 123 , a data transmission module 124 and a slip ring module 125 .

X射线源模块121包括X射线管1211、线束准直器1212及高压电源1213。X射线管1211用于发射X射线源。线束准直器1212与X射线管1211信号连接,用于接收X射线源。高压电源1213与X射线管1211电性连接,用于提供高压电源。在本实施例中,X射线管1211具有较大的热容量,高压电源1213能够提供电压70kV-150kV、电流50mA-300mA的可调电源供X射线管1211使用。The X-ray source module 121 includes an X-ray tube 1211 , a beam collimator 1212 and a high voltage power supply 1213 . X-ray tube 1211 is used to emit X-ray source. The line beam collimator 1212 is connected in signal with the X-ray tube 1211 for receiving the X-ray source. The high-voltage power supply 1213 is electrically connected to the X-ray tube 1211 for providing high-voltage power supply. In this embodiment, the X-ray tube 1211 has a large heat capacity, and the high-voltage power supply 1213 can provide an adjustable power supply with a voltage of 70kV-150kV and a current of 50mA-300mA for the X-ray tube 1211 to use.

X射线检测器模块122用于捕获X射线源,同时将X光子转换成可见光,并将可见光转换成电流信号。X射线检测器模块122包括多个X射线检测器单元(图中未显示),X射线检测器单元以X射线管1211的出线焦点为圆心呈弧状排列。X射线检测器单元由稀土陶瓷材料制成,余辉较短,在单位时间内可以捕获更多的X光子。The X-ray detector module 122 is used to capture the X-ray source while converting the X-photons into visible light and converting the visible light into electrical current signals. The X-ray detector module 122 includes a plurality of X-ray detector units (not shown in the figure), and the X-ray detector units are arranged in an arc shape with the outgoing focal point of the X-ray tube 1211 as the center of a circle. The X-ray detector unit is made of rare-earth ceramic material with shorter afterglow, which can capture more X-photons per unit time.

第一电子学模块123与X射线检测器模块121电性连接,用于处理电流信号,并将电流信号转换成第一图像信息。具体地,第一电子学模块123与X射线源模块121电性连接。第一电子学模块123包含多路功能相同的子模块,实现对电流信号的收集、放大、模拟/数字转换、以及并行/串行转换。第一电子学模块123处理核心采用专用集成电路芯片,以便缩小模块体积,提高集成度和稳定性。The first electronic module 123 is electrically connected with the X-ray detector module 121 and is used for processing the current signal and converting the current signal into first image information. Specifically, the first electronics module 123 is electrically connected to the X-ray source module 121 . The first electronic module 123 includes multiple sub-modules with the same function to realize the collection, amplification, analog/digital conversion, and parallel/serial conversion of current signals. The processing core of the first electronic module 123 adopts an ASIC chip, so as to reduce the volume of the module and improve integration and stability.

数据传输模块124包括发射端1241及接收端1242,用于将第一图像信息传输至图像单元15。发射端1241固定设置于旋转机架1113上。发射端1241一端电性连接于第一电子学模块123,用于接收第一图像信息,并向接收端1242发送。接收端1242与发射端1241正对地固定设置于第一固定机架1111上。接收端1242一端电性连接于图像单元15,用于将数据通过电容耦合、射频或者光传输的方式传递到图像子系统15。The data transmission module 124 includes a transmitting end 1241 and a receiving end 1242 for transmitting the first image information to the image unit 15 . The transmitting end 1241 is fixed on the rotating frame 1113 . One end of the transmitting end 1241 is electrically connected to the first electronic module 123 for receiving the first image information and sending it to the receiving end 1242 . The receiving end 1242 and the transmitting end 1241 are fixedly arranged on the first fixed frame 1111 opposite to each other. One end of the receiving end 1242 is electrically connected to the image unit 15 for transmitting data to the image subsystem 15 through capacitive coupling, radio frequency or optical transmission.

滑环模块125包括多圈环道1251、第一接口单元1252及第二接口单元1253,用于对第一显像单元12传输电力及控制信号。第一接口单元1252,固定设置于第一固定机架1111上。第一接口单元1252的一端与外围电源模块(图未示)以及控制单元14电性连接,另一端与多圈环道1251可滑动接触,用于将外围电源以及控制单元14的控制信号从第一固定机架1111传输给多圈环道1251。第二接口单元1253,其一端与多圈环道1251电性连接,另一端与旋转机架1113的相应单元电性连接,用于接收来自多圈环道1251的外围电源以及控制单元14的控制信号,并将外围电源及控制信号传输给位于旋转机架1113上的相应单元。在本实施例中,相应单元具体为X射线源模块121、X射线检测器模块122、第一电子学模块123、以及数据传输模块124的发射端1241。The slip ring module 125 includes a multi-turn loop 1251 , a first interface unit 1252 and a second interface unit 1253 for transmitting power and control signals to the first display unit 12 . The first interface unit 1252 is fixedly arranged on the first fixed frame 1111 . One end of the first interface unit 1252 is electrically connected to the peripheral power supply module (not shown) and the control unit 14, and the other end is in slidable contact with the multi-turn loop 1251, and is used to transmit the control signals of the peripheral power supply and the control unit 14 from the second A fixed frame 1111 is transferred to a multi-turn loop 1251 . The second interface unit 1253, one end of which is electrically connected to the multi-turn loop 1251, and the other end is electrically connected to the corresponding unit of the rotating frame 1113, for receiving the peripheral power from the multi-turn loop 1251 and the control of the control unit 14 signal, and transmit peripheral power and control signals to the corresponding units on the rotating frame 1113. In this embodiment, the corresponding units are specifically the X-ray source module 121 , the X-ray detector module 122 , the first electronics module 123 , and the transmitting end 1241 of the data transmission module 124 .

第二显像单元13包括γ光子检测器模块131、第二电子学模块132及处理模块133。The second imaging unit 13 includes a gamma photon detector module 131 , a second electronics module 132 and a processing module 133 .

γ光子检测器模131由环绕受检者的多个检测器单元1311组成,检测器单元1311为三层结构,依次包括晶体阵列13111、光导13112和光电转换器件13113。γ光子检测器模块131电性连接于控制单元14,用于采集受检者体内辐射出来的γ光子,并将γ光子转换成电信号,形成探测事件。晶体阵列13111由多个相同尺寸的闪烁晶体单元组成的二维阵列,闪烁晶体单元由晶体材料LYSO(但不限于LYSO)制备而成。The gamma photon detector module 131 is composed of multiple detector units 1311 surrounding the subject. The detector unit 1311 has a three-layer structure, including a crystal array 13111 , a light guide 13112 and a photoelectric conversion device 13113 in sequence. The gamma photon detector module 131 is electrically connected to the control unit 14, and is used for collecting gamma photons radiated from the subject and converting the gamma photons into electrical signals to form detection events. The crystal array 13111 is a two-dimensional array composed of multiple scintillation crystal units of the same size, and the scintillation crystal units are made of crystal material LYSO (but not limited to LYSO).

第二电子学模块132由电连接于光电转换器件13113的多个第二电子学模块单元(图未示)组成。第二电子学模块132用于对γ光子检测器模131输出的探测事件进行放大、模拟/数字转换,把γ光子对的探测信号、对应的位置信息以及时间信息转换成数字信号。The second electronic module 132 is composed of a plurality of second electronic module units (not shown) electrically connected to the photoelectric conversion device 13113 . The second electronics module 132 is used for amplifying and analog/digital converting the detection events output by the gamma photon detector module 131, converting the detection signal of the gamma photon pair, corresponding position information and time information into digital signals.

处理模块133与第二电子学模块132及图像单元15均电性连接,用于对数字信号进行处理以生成第二图像信息,将第二图像信息传输至图像单元15。The processing module 133 is electrically connected to the second electronic module 132 and the image unit 15 , and is used to process the digital signal to generate the second image information, and transmit the second image information to the image unit 15 .

控制单元14包括主控制器141及与主控制器141电性连接的控制计算机142。控制单元14包括主控制器141及与主控制器141电性连接的控制计算机142。主控制器141在组成上至少包含处理器、内存及若干个通信接口单元。其中,通信接口包括串口、以太网口、CAN接口等的一种或多种,用于实现主控制器141与控制计算机142、第一显像单元12以及第二显像单元13等各个被控单元之间进行通信。控制计算机142包括一套用于控制和显示的操作界面,实现所有的人机交互功能。The control unit 14 includes a main controller 141 and a control computer 142 electrically connected to the main controller 141 . The control unit 14 includes a main controller 141 and a control computer 142 electrically connected to the main controller 141 . The main controller 141 is composed of at least a processor, a memory, and several communication interface units. Wherein, the communication interface includes one or more of a serial port, an Ethernet port, a CAN interface, etc., and is used to realize each controlled connection between the main controller 141 and the control computer 142, the first display unit 12, and the second display unit 13. communicate between units. The control computer 142 includes a set of operation interfaces for control and display, and realizes all human-computer interaction functions.

主控制器141与第二接口单元1253电性连接,用于将控制信号通过第二接口单元1253从第一固定机架1111传输给旋转机架1113上的相应单元。可以理解,高压电源1213通过第二接口单元1253接收来自主控制器141的控制信号以及外围供电子系统的电力,对X射线的输出进行调节。同时高压电源1213通过第二接口单元1253向主控制器141反馈X射线源的工作状态信息。X射线检测器模块122与X射线源模块121的X射线管1211和线束准直器1212相对,由X射线管1211发出的X射线经过线束准直器1212准直后穿透受检者,剩余的X射线由X射线检测器模块122捕获,经第一电子学模块123转换成能够反映受检者结构信息的高速数字信号,即第一图像信息。第一图像信息再通过发射端1241及接收端1242,传输至图像单元15。在本实施例中,第一图像信息为计算机断层投影图像。The main controller 141 is electrically connected to the second interface unit 1253 for transmitting control signals from the first fixed frame 1111 to corresponding units on the rotating frame 1113 through the second interface unit 1253 . It can be understood that the high-voltage power supply 1213 receives the control signal from the main controller 141 and the power of the peripheral power supply subsystem through the second interface unit 1253 to adjust the output of X-rays. At the same time, the high-voltage power supply 1213 feeds back the working state information of the X-ray source to the main controller 141 through the second interface unit 1253 . The X-ray detector module 122 is opposite to the X-ray tube 1211 and the line beam collimator 1212 of the X-ray source module 121, and the X-ray emitted by the X-ray tube 1211 passes through the subject after being collimated by the line beam collimator 1212, and the rest The X-rays are captured by the X-ray detector module 122 and converted by the first electronic module 123 into high-speed digital signals capable of reflecting structural information of the subject, that is, first image information. The first image information is then transmitted to the image unit 15 through the transmitting end 1241 and the receiving end 1242 . In this embodiment, the first image information is a computed tomography projection image.

主控制器141还电性连接于第二电子学模块132及处理模块133,主控制器141接受来自控制计算机142的指令,启动或停止第二电子学模块132的采集动作,对处理模块133进行参数配置,并检测、收集来自第二电子学模块132以及控制处理模块133,实现处理模块133对来自第二电子学模块132的数字信号进行符合分析,收集有效的符合事件,剔除假符合和随机符合事件,以生成第二图像信息,并将第二图像信息传输至图像单元15。在本实施例中,第二图像信息为γ光子对符合事件信息。The main controller 141 is also electrically connected to the second electronic module 132 and the processing module 133, the main controller 141 receives instructions from the control computer 142, starts or stops the acquisition action of the second electronic module 132, and performs the processing on the processing module 133. Parameter configuration, and detection and collection from the second electronics module 132 and the control processing module 133, so that the processing module 133 can perform coincidence analysis on the digital signal from the second electronics module 132, collect valid coincidence events, and eliminate false coincidence and random According to the event, the second image information is generated, and the second image information is transmitted to the image unit 15 . In this embodiment, the second image information is gamma photon pair coincidence event information.

主控制器141还电性连接于第二定子11141,用于控制力矩电机1114的旋转。主控制器141还电性连接于第三定子11151,用于采集第一位置传感器1115的信息。可以理解,第一位置传感器1115通过采集第三定子11151与第三转子11152之间的感应电势间接测量力矩电机1114的旋转位置被主控制器141获取。The main controller 141 is also electrically connected to the second stator 11141 for controlling the rotation of the torque motor 1114 . The main controller 141 is also electrically connected to the third stator 11151 for collecting information from the first position sensor 1115 . It can be understood that the first position sensor 1115 indirectly measures the rotational position of the torque motor 1114 by collecting the induced potential between the third stator 11151 and the third rotor 11152 and is acquired by the main controller 141 .

图像单元15电性连接于接收端1242及处理模块133。图像单元15用于对第一图像信息及第二图像信息进行重建、配准及融合。图像单元15为采用单一的图像处理器或组合的多个图像处理器,其实现方式可以但不限于如下所述:单一的图像处理器为FPGA控制下的单个DSP芯片,组合的多个处理器为FPGA控制下的多个DSP芯片构成的阵列。单一的图像处理器为一个单核CPU或一个多核CPU,组合的多个处理器为一个多核CPU或若干个多核CPU。单一的图像处理器为CPU控制下的一个通用计算性图形处理器,组合的多个处理器为CPU控制下的若干个计算性图形处理器组成的阵列。The image unit 15 is electrically connected to the receiving end 1242 and the processing module 133 . The image unit 15 is used to reconstruct, register and fuse the first image information and the second image information. Image unit 15 is to adopt a single image processor or a plurality of image processors combined, and its implementation can be but not limited to as follows: a single image processor is a single DSP chip under FPGA control, and a plurality of processors combined It is an array composed of multiple DSP chips under the control of FPGA. A single image processor is a single-core CPU or a multi-core CPU, and multiple processors combined are a multi-core CPU or several multi-core CPUs. A single image processor is a general-purpose computational graphics processor under the control of the CPU, and the combined multiple processors are an array composed of several computational graphics processors under the control of the CPU.

诊断床单元16电性连接于主控制器141,受主控制器141控制实现升降。诊断床单元16包括床板161、升降立柱162、导轨底座163、诊断床控制器164、第二位置感应器165及第三位置感应器166。床板161采用碳纤维材料制成,能够支承受检者的体重且床板形变较小,并能尽量少的阻挡X射线。升降立柱162,固定连接于床板161,具有升降电机1621,用于驱动床板161沿竖直方向运动。导轨底座163,,承载升降立柱162,具有水平电机1631,用于驱动床板161及升降立柱沿水平方向移动。诊断床控制器164,固定设置于升降立柱162的内部,且电性连接于主控制器141,升降电机及水平电机,用于控制床板161的水平方向移动及升降立柱的竖直方向运动。第二位置感应器165,与水平电机1631固定连接,用于定位床板161的水平位置;及第三位置感应器166,与升降电机1621固定连接,用于定位床板161的垂直高度。The diagnostic bed unit 16 is electrically connected to the main controller 141, and is controlled by the main controller 141 to realize lifting. The diagnostic bed unit 16 includes a bed board 161 , a lifting column 162 , a rail base 163 , a diagnostic bed controller 164 , a second position sensor 165 and a third position sensor 166 . The bed board 161 is made of carbon fiber material, which can support the body weight of the examinee with little deformation of the bed board and can block X-rays as little as possible. The lifting column 162 is fixedly connected to the bed board 161 and has a lifting motor 1621 for driving the bed board 161 to move vertically. The rail base 163' carries the lifting column 162 and has a horizontal motor 1631 for driving the bed board 161 and the lifting column to move horizontally. The diagnostic bed controller 164 is fixedly installed inside the lifting column 162, and is electrically connected to the main controller 141, the lifting motor and the horizontal motor, and is used to control the horizontal movement of the bed board 161 and the vertical movement of the lifting column. The second position sensor 165 is fixedly connected with the horizontal motor 1631 for positioning the horizontal position of the bed board 161 ; and the third position sensor 166 is fixedly connected with the lifting motor 1621 for positioning the vertical height of the bed board 161 .

主控制器141还电性连接于第二位置传感器165,用于采集第二位置传感器165的信息。主控制器141还电性连接于诊断床控制器164,用于控制诊断床单元16的水平移动及升降运动,同时,采集并反馈第二位置传感器165及第三位置传感器166信息。The main controller 141 is also electrically connected to the second position sensor 165 for collecting information of the second position sensor 165 . The main controller 141 is also electrically connected to the diagnostic bed controller 164 for controlling the horizontal movement and lifting movement of the diagnostic bed unit 16 , and at the same time, collects and feeds back information from the second position sensor 165 and the third position sensor 166 .

请参阅图10,为本发明实施例提供的双模融合的医学成像方法的流程示意图,具体步骤如下:Please refer to FIG. 10 , which is a schematic flowchart of a medical imaging method for dual-mode fusion provided by an embodiment of the present invention, and the specific steps are as follows:

步骤S10:建立以诊断床单元16为基准的坐标。Step S10: Establish coordinates based on the diagnostic bed unit 16.

步骤S20:定位第一显像单元12及定位第二显像单元13。Step S20: Positioning the first display unit 12 and positioning the second display unit 13 .

建立以诊断床单元16为基准的坐标为参考坐标,调整第一显像单元12在机架单元11上的位置及调整第二显像单元13在机架单元11上的位置,使得第一显像单元12的成像中心及第二显像单元13成像中心处于同一水平线上,这样在结构上保证第一显像单元12和第二显像单元13的成像中心严格配准,尽可能地避免了因成像坐标系不同而引起的配准误差。Establish the coordinates based on the diagnostic bed unit 16 as the reference coordinates, adjust the position of the first imaging unit 12 on the rack unit 11 and adjust the position of the second imaging unit 13 on the rack unit 11, so that the first imaging unit 12 The imaging center of the imaging unit 12 and the imaging center of the second imaging unit 13 are on the same horizontal line, thus structurally ensuring that the imaging centers of the first imaging unit 12 and the second imaging unit 13 are strictly registered, avoiding as much as possible Registration error due to different imaging coordinate systems.

步骤S30:通过控制单元14控制第一显像单元12及第二显像单元13,并分别生成第一图像信息及第二图像信息。Step S30: Control the first display unit 12 and the second display unit 13 through the control unit 14, and generate first image information and second image information respectively.

请参阅图11,为本发明实施例提供的生成第一图像信息及第二图像信息的流程图,具体步骤包括:Please refer to FIG. 11 , which is a flow chart for generating the first image information and the second image information provided by the embodiment of the present invention, and the specific steps include:

步骤S31:通过控制单元14对第一显像单元12及第二显像单元13的工作参数进行设置。操作人员通过控制单元14的控制计算机142输入参数,参数经过控制计算机142底层封装后,通过控制单元14上的通信接口传输至主控制器141,由主控制器141对参数进行解析,并通过通信接口转发至第一显像单元12及第二显像单元13的功能模块;通过主控制器141工作参数的配置结果反馈至控制计算机142。Step S31 : setting the working parameters of the first display unit 12 and the second display unit 13 through the control unit 14 . The operator inputs parameters through the control computer 142 of the control unit 14. After the parameters are packaged at the bottom layer of the control computer 142, they are transmitted to the main controller 141 through the communication interface on the control unit 14. The main controller 141 analyzes the parameters and communicates The interface is forwarded to the functional modules of the first display unit 12 and the second display unit 13 ; the configuration result of the working parameters is fed back to the control computer 142 through the main controller 141 .

步骤S32:通过控制单元14对受检者的扫描范围进行设置。操作人员通过控制计算机142显控界面规划人体待检部位沿诊断床单元16水平移动方向(轴向方向)的长度,主控制器141将该长度分别映射为在第一显像单元12及第二显像单元13下诊断床单元16需移动的范围,并确定诊断床单元16扫描起始位置。Step S32: Setting the scanning range of the subject through the control unit 14 . The operator plans the length of the part of the human body to be examined along the horizontal movement direction (axial direction) of the diagnostic bed unit 16 through the display and control interface of the control computer 142, and the main controller 141 maps the length to the first imaging unit 12 and the second imaging unit 12 respectively. The imaging unit 13 determines the moving range of the diagnostic bed unit 16 and determines the scanning starting position of the diagnostic bed unit 16 .

步骤S33:控制单元14控制诊断床单元16移动,第一显像单元12按照预先设置的工作参数进行数据采集,以生成第一图像信息。通过主控制器141发送扫描起始指令,控制诊断床单元16运动至第一显像单元12起始位置;诊断床单元16自该起始位置起持续运动,同时第一显像单元12成像链按照设定的工作方式持续进行曝光和投影数据采集,采集的数据通过数据传输模块124传递至图像单元15进行后续的软件处理工作。Step S33: the control unit 14 controls the movement of the diagnostic bed unit 16, and the first imaging unit 12 performs data collection according to preset working parameters to generate first image information. The scan start command is sent by the main controller 141 to control the diagnostic bed unit 16 to move to the initial position of the first imaging unit 12; the diagnostic bed unit 16 continues to move from the initial position, while the first imaging unit 12 imaging chain Continuously collect exposure and projection data according to the set working mode, and transmit the collected data to the image unit 15 through the data transmission module 124 for subsequent software processing.

步骤S34:控制单元14控制诊断床单元16移动,第二显像单元13按照预先设置的工作参数进行数据采集,以生成第二图像信息。在第一显像单元12显像过程结束后,通过主控制器141发送第二显像单元13显像扫描起始指令,控制诊断床单元16运动至第二显像单元13的第一个待显像位置停止,然后启动第二显像单元13的γ光子检测器模131进行γ光子的采集,采集的数据经过第二电子学模块132的处理,再通过处理模块133传递至图像单元15进行后续的软件处理工作。Step S34: the control unit 14 controls the movement of the diagnostic bed unit 16, and the second imaging unit 13 performs data collection according to preset working parameters to generate second image information. After the imaging process of the first imaging unit 12 ends, the main controller 141 sends the imaging and scanning start instruction of the second imaging unit 13 to control the diagnostic bed unit 16 to move to the first waiting area of the second imaging unit 13. The imaging position is stopped, and then the gamma photon detector module 131 of the second imaging unit 13 is started to collect gamma photons. The collected data is processed by the second electronic module 132, and then transmitted to the image unit 15 through the processing module 133 for further processing. Subsequent software processing work.

上述步骤中,第一显像单元12及第二显像单元13显像结束后,将诊断床单元16移动至下一个待显像位置,重复上述步骤S30,直至完成整个设定扫描范围的数据采集,才终止整个扫描流程。In the above steps, after the imaging of the first imaging unit 12 and the second imaging unit 13 is completed, the diagnostic bed unit 16 is moved to the next position to be developed, and the above step S30 is repeated until the data of the entire set scanning range is completed. acquisition, the entire scanning process is terminated.

步骤S40:通过图像单元15重建第一图像信息及第二图像信息。在完成重建第一图像信息之前还包括对第一图像信息的射束硬化校正的步骤。基于第一显像单元12及第二显像单元13采集的第一图像信息及第二图像信息分别进行图像重建,其中,第一图像信息在重建之前要先由图像单元完成射束硬化校正工作,第二图像信息为初次重建且未经过软件配准。Step S40: Reconstruct the first image information and the second image information through the image unit 15 . A beam hardening correction step for the first image information is also included before the reconstruction of the first image information is completed. Image reconstruction is carried out based on the first image information and the second image information collected by the first imaging unit 12 and the second imaging unit 13 respectively, wherein the first image information needs to be corrected by the image unit before reconstruction , the second image information is the initial reconstruction and has not been registered by software.

步骤S50:通过图像单元15配准经重建后的第一图像信息及第二图像信息。Step S50 : register the reconstructed first image information and second image information through the image unit 15 .

请参阅图12,为本发明实施例提供的配准经重建后的第一图像信息及第二图像信息的流程图,包括下述步骤:Please refer to FIG. 12 , which is a flow chart of registering the reconstructed first image information and second image information provided by the embodiment of the present invention, including the following steps:

步骤S51:对经重建后的第一图像信息及第二图像信息进行初次配准。对经重建后的第一图像信息及第二图像信息进行软件上的初次配准,配准参数主要用于第二图像信息的衰减校正。Step S51: Initially register the reconstructed first image information and second image information. The first software registration is performed on the reconstructed first image information and the second image information, and the registration parameters are mainly used for attenuation correction of the second image information.

步骤S52:基于经初次配准后的第一图像信息获得的衰减校正因子对经初次配准后的第二图像信息进行衰减校正。利用经初次配准后的第一图像信息生成衰减校正因子,并基于获得的衰减校正因子对第二图像信息的符合事件数据进行衰减校正,提高第二显像单元13的定位精确性和图像对比度。Step S52: performing attenuation correction on the second image information after the initial registration based on the attenuation correction factor obtained from the first image information after the initial registration. Utilize the first image information after initial registration to generate an attenuation correction factor, and perform attenuation correction on the coincident event data of the second image information based on the obtained attenuation correction factor, so as to improve the positioning accuracy and image contrast of the second imaging unit 13 .

步骤S53:对经衰减校正后的第二图像信息进行二次图像重建。对衰减校正后的第二显像单元13的符合事件数据进行二次图像重建。Step S53: performing secondary image reconstruction on the attenuation-corrected second image information. Secondary image reconstruction is performed on the attenuation-corrected coincident event data of the second imaging unit 13 .

步骤S54:对经二次图像重建获得的第二图像信息及经重建后第一图像信息进行再次配准。将经过衰减校正后重建的第二图像信息与重建后的第一图像信息进行再次配准,获得更加精确的配准参数。Step S54: re-register the second image information obtained through the secondary image reconstruction and the reconstructed first image information. The reconstructed second image information after attenuation correction is re-registered with the reconstructed first image information to obtain more accurate registration parameters.

请参阅图13,为图像配准的流程图。请参阅图13a图像配准部是图像单元的一个组成部分,包括几何变换、图像插值、相似性度量以及优化这四个相对独立的模块。令f(x)表示第一图像信息,m(x)表示第二图像信息,T(x)表示几何变换参数,T(m(x))表示用几何变换参数T(x),用于将第二图像信息空间映射到第一图像信息空间。图像配准部的处理可以理解成一个迭代处理流程。具体包括下述步骤:Please refer to Figure 13 for a flowchart of image registration. Please refer to Figure 13a. The image registration unit is a component of the image unit, including four relatively independent modules of geometric transformation, image interpolation, similarity measurement and optimization. Let f(x) represent the first image information, m(x) represent the second image information, T(x) represent the geometric transformation parameter, and T(m(x)) represent the geometric transformation parameter T(x), which is used to convert The second image information space is mapped to the first image information space. The processing of the image registration unit can be understood as an iterative processing flow. Specifically include the following steps:

步骤S501:图像单元15输入第一图像信息及第二图像信息,并分别记为f(x)、m(x)。Step S501: The image unit 15 inputs the first image information and the second image information, which are denoted as f(x) and m(x) respectively.

步骤S502:通过图像单元15设置初始配准参数。Step S502: Set initial registration parameters through the image unit 15 .

步骤S503:对空间分辨率较低的第二图像信息m(x)进行插值。Step S503: Perform interpolation on the second image information m(x) with a lower spatial resolution.

步骤S504:图像单元15计算在初始配准参数下第一图像信息及第二图像信息的互信息相似性函数。Step S504: The image unit 15 calculates the mutual information similarity function of the first image information and the second image information under the initial registration parameters.

步骤S505:图像单元15通过基于梯度下降的优化方法计算下一步的几何变换参数,直至第一图像信息及第二图像信息的互信息相似性函数达到极大值,迭代终止。Step S505: The image unit 15 calculates the geometric transformation parameters for the next step through an optimization method based on gradient descent until the mutual information similarity function of the first image information and the second image information reaches a maximum value, and the iteration is terminated.

步骤S506:图像单元15输出最终的精确配准参数T*(x)。Step S506: The image unit 15 outputs the final precise registration parameter T * (x).

步骤S60:图像单元15融合经配准后的第一图像信息及第二图像信息。Step S60: The image unit 15 fuses the registered first image information and the second image information.

请参阅图14,为本发明实施例提供的融合经配准后的第一图像信息及第二图像信息的流程图,包括下述步骤:Please refer to FIG. 14 , which is a flow chart of fusing the registered first image information and second image information provided by the embodiment of the present invention, including the following steps:

步骤S61:对经再次配准后的第一图像信息及第二图像信息进行小波分解。首先采用基于小波变换的算法对经再次配准后的第一图像信息及第二图像信息进行多层次分解,每一分解层产生4幅子图像LL、HL、LH以及HH,分别代表着图像的低频成分、水平方向高频成分、垂直方向高频成分以及对角方向高频成分。将高频子图像分成3×3或5×5的子块,对每个子块图像进行统计分析计算其区域方差。Step S61: performing wavelet decomposition on the re-registered first image information and second image information. Firstly, the wavelet transform-based algorithm is used to decompose the re-registered first image information and second image information at multiple levels, and each decomposition layer generates four sub-images LL, HL, LH, and HH, which represent the images respectively. Low-frequency components, high-frequency components in the horizontal direction, high-frequency components in the vertical direction, and high-frequency components in the diagonal direction. Divide the high-frequency sub-image into 3×3 or 5×5 sub-blocks, and perform statistical analysis on each sub-block image to calculate its regional variance.

步骤S62:确定融合图像的小波分解系数。对低频分量以及高频分量分别采用不同的融合规则确定融合图像的各小波分解系数,即低频分量采用对应点绝对值取大的融合规则,加权融合规则,对区域方差较大的子块赋予较大的加权系数,得到融合图像的小波金字塔分解。Step S62: Determine the wavelet decomposition coefficients of the fused image. Different fusion rules are used for the low-frequency components and high-frequency components to determine the wavelet decomposition coefficients of the fused image, that is, the low-frequency components adopt the fusion rule that takes the larger absolute value of the corresponding point, and the weighted fusion rule assigns a higher value to the sub-block with a larger regional variance. A large weighting coefficient can be used to obtain the wavelet pyramid decomposition of the fused image.

步骤S63:进行逆小波变换得到第一图像信息及第二图像信息的融合图像。Step S63: performing inverse wavelet transform to obtain a fused image of the first image information and the second image information.

上述双模融合的医学成像系统将第一显像单元12及第二显像单元13精确固定在机架单元11上,通过调整第一显像单元12及第二显像单元13,使得第一显像单元12及第二显像单元13的成像中心处于同一水平线上,保证了第一显像单元12及第二显像单元13的图像采集坐标系相统一;同时采用统一的控制单元14,使第一显像单元12及第二显像单元13的显像时间间隔尽量短,减少受检者身体不自主移位对图像配准造成的影响;然后将采集的第一图像信息及第二图像信息传输至图像单元15,并进行图像重建,再对重建后的第一图像信息及第二图像信息进行二次配准,提升了配准精度,大幅改善了后续的图像融合质量。The medical imaging system with dual-mode fusion described above precisely fixes the first imaging unit 12 and the second imaging unit 13 on the rack unit 11, and adjusts the first imaging unit 12 and the second imaging unit 13 so that the first The imaging centers of the imaging unit 12 and the second imaging unit 13 are on the same horizontal line, which ensures that the image acquisition coordinate systems of the first imaging unit 12 and the second imaging unit 13 are unified; while adopting a unified control unit 14, Make the imaging time interval of the first imaging unit 12 and the second imaging unit 13 as short as possible to reduce the influence of the involuntary movement of the subject's body on the image registration; then the collected first image information and the second The image information is transmitted to the image unit 15, and the image is reconstructed, and then the reconstructed first image information and the second image information are registered twice, which improves the registration accuracy and greatly improves the subsequent image fusion quality.

以上所述,仅是本发明的较佳实施例而已,并非对本发明作任何形式上的限制,虽然本发明已以较佳实施例揭露如上,然而并非用以限定本发明,任何熟悉本专业的技术人员,在不脱离本发明技术方案范围内,当可利用上述揭示的技术内容作出些许更动或修饰为等同变化的等效实施例,但凡是未脱离本发明技术方案内容,依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与修饰,均仍属于本发明技术方案的范围内。The above description is only a preferred embodiment of the present invention, and does not limit the present invention in any form. Although the present invention has been disclosed as above with preferred embodiments, it is not intended to limit the present invention. Anyone familiar with this field Those skilled in the art, without departing from the scope of the technical solution of the present invention, may use the technical content disclosed above to make some changes or modify them into equivalent embodiments with equivalent changes, but as long as they do not depart from the technical solution of the present invention, the Technical Essence Any simple modifications, equivalent changes and modifications made to the above embodiments still fall within the scope of the technical solution of the present invention.

Claims (14)

1. a medical image system for bimodulus fusion, is characterized in that, comprising:
Rack unit, comprising:
Base;
First frame, comprising:
First fixed frame, is fixed on described base;
Outer ring spring bearing, comprise the first mutually corresponding stator and the first rotor, described first stator is fixed on described first fixed frame;
Rotary frame, described rotary frame is arranged on described first fixed frame by described the first rotor;
Torque motor, is fixedly connected on described first fixed frame and described rotary frame; And
Primary importance sensor, is fixedly connected on described torque motor, for gathering the position of rotation of described torque motor; And
Second frame, comprises the second fixed frame, and described second fixed frame is two, is fixed on rack unit base movably;
First visualization unit, be fixedly installed in described first frame, described first visualization unit is x-ray tomography visualization unit;
Second visualization unit, be fixedly installed in described second frame, be set up in parallel before and after described second visualization unit and described first visualization unit, and the imaging center point of described first visualization unit and described second visualization unit imaging center point are on same level line, described second visualization unit is positron radionuclide visualization unit;
Control unit, be electrically connected at described primary importance sensor, described first visualization unit and described second visualization unit, for gathering the positional information of described torque motor and controlling described first visualization unit and generate the first image information and described second visualization unit generates the second image information, described first image information is computerized tomography projected image, and described second image information is that γ photon is to meeting event information;
Elementary area, is electrically connected at described first visualization unit and the second visualization unit, for receiving described first image information and described second image information, and described first image information and described second image information are rebuild, registration and fusion calculation; And
Diagnostic bed unit, is electrically connected at described control unit, moves horizontally and elevating movement by described control unit control realization, and wherein, described x-ray tomography visualization unit comprises:
X-ray source module, for providing X-ray;
X-ray detector module, for catching described x-ray source, converts X-ray to visible ray simultaneously, and converts described visible ray to the signal of telecommunication;
First electronics module, is electrically connected with described X-ray detector module, for the treatment of the described signal of telecommunication, and converts the described signal of telecommunication to described first image information;
Slip ring modules, is electrically connected at described x-ray source module and described control unit, for described ray tomography unit transferring electric power and control signal; And
Data transmission module, for described first image information being transferred to described elementary area by medium, described slip ring modules comprises:
Multi-turn circuit, is fixedly installed on the inner ring of described rotary frame around ground;
First interface unit, be fixedly installed on described first fixed frame, its one end and peripheral power supply module and described control unit are electrically connected, the other end and described multi-turn circuit slidingly contact, for the control signal of peripheral power supply and described control unit is transferred to described multi-turn circuit from described first fixed frame; And
Second interface unit, its one end and described multi-turn circuit are electrically connected, and the corresponding units of the other end and described rotary frame is electrically connected, for the control signal of described peripheral power supply and described control unit being transferred to the corresponding units of described rotary frame.
2. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described torque motor, comprise the second stator, the second rotor and bearing, described second stator one end is fixedly connected on described first fixed frame, the other end is fixed on described bearing, and described second rotor is fixedly connected with described rotary frame.
3. the medical image system of bimodulus fusion according to claim 2, it is characterized in that, described primary importance sensor, comprise the 3rd stator and third trochanter, described 3rd stator is fixedly connected with described second stator, described third trochanter is fixedly connected with described second rotor, and described primary importance sensor is for gathering the position of rotation of described torque motor.
4. the medical image system that merges of bimodulus according to claim 1, is characterized in that, described medium is the capacitance signal of described first modulate image information, radiofrequency signal or optical signal.
5. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described x-ray source module, comprising:
X-ray tube, launches x-ray source;
Beam collinmator, is fixedly connected with described X-ray tube, for filtering unnecessary X-ray; And
High voltage power supply, is electrically connected with described X-ray tube, for providing heater current and high voltage power supply for described X-ray tube, and controls X-ray generation.
6. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described X-ray detector module comprises multiple X-ray detector unit, described multiple X-ray detector unit with described X-ray tube go out line focus for the center of circle be arcuation arrangement.
7. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described data transmission module, comprising:
Transmitting terminal, is fixedly installed on described rotary frame, and its one end is electrically connected at described first electronics module, for launching described first image information;
Receiving terminal, rectify with described transmitting and be fixedly installed on over the ground on described first fixed frame, its one end is electrically connected at described elementary area, for receiving described first image information, and described first image information is transferred to described elementary area.
8. the medical image system of bimodulus fusion according to claim 3, it is characterized in that, described positron radionuclide visualization unit comprises:
γ photon detector module, for gathering person under inspection's internal radiation γ photon out, and becomes the signal of telecommunication by described γ photon conversion, forms detection event;
Second electronics module, is all electrically connected with described γ photon detector module and described control power supply, forms digital signal for carrying out process to described detection event;
Processing module, is all electrically connected with described second electronics module and described elementary area, generates described second image information, and described second image information is transferred to described elementary area for processing described digital signal.
9. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described diagnostic bed unit, comprising:
Bed board;
Lifting column, is fixedly connected on described bed board, has lifting motor, vertically moves for driving described bed board;
Guiderail base, carries described lifting column, has horizontal motor, moves in the horizontal direction for driving described bed board and described lifting column;
Second position induction apparatus, is fixedly connected with described horizontal motor, for locating the horizontal level of described bed board;
3rd position sensor, is fixedly connected with described lifting motor, for locating the vertical height of described bed board; And
Diagnostic bed controller, be fixedly installed on the inside of described lifting column, and be electrically connected at master controller, described lifting motor and described horizontal motor, horizontal direction for controlling described bed board moves and the vertical direction of described lifting column moves, and gathers and feeds back described second position sensor and described 3rd position sensor information.
10. the medical image system of bimodulus fusion according to claim 8, it is characterized in that, described control unit comprises:
Master controller; And
Computer for controlling, described computer for controlling and described master controller are electrically connected;
It is electrical that described master controller is connected to described second interface unit, for control signal is transferred to described multi-turn circuit by described second interface unit from described first fixed frame;
Described master controller is also electrically connected at described second stator, for controlling the rotation of described torque motor;
Described master controller is also electrically connected at described 3rd stator, for gathering the information of described primary importance sensor;
Described master controller is also electrically connected at described second electronics module and described processing module, for the instruction according to described computer for controlling, controls described second electronics module and described processing module, to generate described second image information.
The medical image system that 11. bimodulus according to claim 1 merge, is characterized in that, described elementary area is the multiple image processors adopting single image processor or combination.
The medical image system that 12. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is the single dsp chip under FPGA controls, and multiple processors of described combination are the array that the multiple dsp chips under FPGA controls are formed.
The medical image system that 13. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is a monokaryon CPU or multi-core CPU, and multiple processors of described combination are a multi-core CPU or several multi-core CPUs.
The medical image system that 14. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is a general-purpose computations type graphic process unit (GPU) under CPU controls, and multiple processors of described combination are the array that several general-purpose computations type graphic process unit (GPU) under CPU controls form.
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