CN102920470B - The medical image system that bimodulus merges and method - Google Patents

Abstract

A medical imaging system with dual-mode fusion, comprising: a rack unit; a first imaging unit; a second imaging unit, the first imaging unit and the second imaging unit are arranged side by side on the rack unit, and the second The imaging central point of the first imaging unit and the imaging central point of the second imaging unit are on the same horizontal line; the control unit is electrically connected to the first imaging unit and the second imaging unit, and is used to control the first imaging unit to generate The first image information and the second display unit generate second image information; the image unit is electrically connected to the first display unit and the second display unit, and is used to reconstruct the first image information and the second image information, Registration and fusion; the diagnostic bed unit is electrically connected to the control unit, and is controlled by the control unit to realize horizontal movement and lifting movement. The invention also provides a dual-mode fusion medical imaging method. The dual-mode fusion medical imaging system provided by the present invention improves image registration precision and improves image fusion quality.

Description

Dual-modal fusion medical imaging system and method

technical field

The invention relates to the field of medical imaging, in particular to a dual-mode fusion medical imaging system and method.

Background technique

Positron tomography (PET) can provide functional images of human metabolism, but the signal-to-noise ratio and spatial resolution of PET are very low. Tomographic imaging (CT) technology has clear images and high spatial resolution, which can provide a good reference for the location of lesions, but its display effect on lesions itself is relatively poor. Therefore, PET images and CT images can be fused to achieve better imaging effects.

At present, in the field of medical image fusion, most of the images to be fused are obtained from different machines due to limitations in equipment manufacturing and use. The images acquired by different machines cannot be acquired synchronously, and it is difficult to unify the acquisition coordinate systems of the two, so the image registration accuracy of different imaging modes is not high, which affects the quality of the fused image.

Contents of the invention

Based on this, it is necessary to provide a dual-mode fusion medical imaging system with high registration accuracy for the defects of the above fusion medical images.

A dual-mode fusion medical imaging system, comprising:

rack unit, including:

base;

First rack, including:

a first fixed frame, fixed on the base;

The outer ring support bearing includes a first stator and a first rotor corresponding to each other, and the first stator is fixed on the first fixed frame;

a rotating frame, the rotating frame is arranged on the first fixed frame through the first rotor;

a torque motor fixedly connected to the first fixed frame and the rotating frame; and

a first position sensor, fixedly connected to the torque motor, for collecting the rotational position of the torque motor; and

The second frame includes a second fixed frame, and the second fixed frame is fixed on the base;

The first imaging unit is fixedly arranged on the first frame;

The second imaging unit is fixedly arranged on the second frame, the second imaging unit is arranged side by side with the first imaging unit, and the imaging center point of the first imaging unit is aligned with the first imaging unit. The imaging central point of the second imaging unit is on the same horizontal line;

A control unit, electrically connected to the first position sensor, the first display unit and the second display unit, for collecting the position information of the torque motor and controlling the first display unit generating first image information and said second display unit generating second image information,

An image unit, electrically connected to the first image display unit and the second image display unit, for receiving the first image information and the second image information, and analyzing the first image information and the second image information 2. Image information is reconstructed, registered and fused; and

The diagnostic bed unit is electrically connected to the control unit, and is controlled by the control unit to realize horizontal movement and lifting movement.

A medical imaging method for dual-mode fusion, comprising the following steps: establishing coordinates based on the diagnostic bed; positioning the first imaging unit and positioning the second imaging unit to achieve structural registration; The control unit controls the first imaging unit and the second imaging unit, and generates first image information and second image information respectively; wherein, the control unit collects the first image information or the Simultaneously with the second image information, respectively collect the position information of the torque motor and the diagnostic bed unit; based on the first image information, the second image information and the position information, reconstruct the first image information and the second image information; registering the reconstructed first image information and the second image information; fusing the registered first image information and the second image information.

The medical imaging system with dual-mode fusion described above precisely fixes the first imaging unit and the second imaging unit on the frame unit, and adjusts the first imaging unit and the second imaging unit so that the first imaging unit and the second imaging unit The imaging centers of the two imaging units are on the same horizontal line, which ensures that the image acquisition coordinate systems of the first imaging unit and the second imaging unit are unified; at the same time, a unified control unit is adopted to optimize the control process, so that the first imaging unit and the imaging time interval of the second imaging unit as short as possible to reduce the impact of the involuntary body movement of the subject on image registration; then the collected first image information and second image information are transmitted to the image unit, and Image reconstruction is performed, and then secondary registration is performed on the reconstructed first image information and second image information, which improves the registration accuracy and greatly improves the subsequent image fusion quality.

Description of drawings

FIG. 1 is a schematic plan view of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

Fig. 2 is a three-dimensional structure diagram of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

Fig. 3 is a three-dimensional exploded view of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

Fig. 4 is a schematic structural diagram of a side of a first rack provided by an embodiment of the present invention.

FIG. 5 is a partially enlarged structural schematic diagram of a side surface of a first rack provided by an embodiment of the present invention.

Fig. 6 is a schematic perspective view of the diagnostic bed unit provided by the embodiment of the present invention.

FIG. 7 is a schematic structural diagram of a first imaging unit of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

FIG. 8 is a schematic structural diagram of a second imaging unit of a dual-mode fusion medical imaging system provided by an embodiment of the present invention.

FIG. 9 is a schematic structural diagram of a detector unit of a second imaging unit provided by an embodiment of the present invention.

FIG. 10 is a schematic flowchart of a medical imaging method for dual-mode fusion provided by an embodiment of the present invention.

FIG. 11 is a schematic flow chart of generating first image information and second image information in a dual-mode fusion medical imaging method provided by an embodiment of the present invention.

Fig. 12 is a flow chart of registering reconstructed first image information and second image information provided by an embodiment of the present invention.

Fig. 13 is a flowchart of image registration provided by an embodiment of the present invention.

Fig. 13a is a structural diagram of an image registration unit provided by an embodiment of the present invention.

Fig. 14 is a flow chart of fusing registered first image information and second image information provided by an embodiment of the present invention.

Detailed ways

Please refer to Figure 1 to Figure 9. The dual-mode fusion medical imaging system 10 includes: a rack unit 11 , a first imaging unit 12 , a second imaging unit 13 , a control unit 14 , an image unit 15 and a diagnostic bed unit 16 .

The frame unit 11 includes a base 110 , a first frame 111 , a second frame 112 and a scanning hole 113 . The main body of the frame unit 11 is made of steel structure, or other alloy materials with similar strength, so as to ensure that the deformation of the frame is extremely small.

The first frame 111 includes a first fixed frame 1111 , an outer ring support bearing 1112 , a rotating frame 1113 , a torque motor 1114 and a first position sensor 1115 . The first fixed frame 1111 is fixed on the base of the frame unit 11 . The outer ring support bearing 1112 includes a first stator (not shown) and a first rotor (not shown) corresponding to each other, and the first stator is fixed on the first fixed frame 1111 . The rotating frame 1113 is fixed on the first fixed frame 1111 through the first rotor. The torque motor 1114 is fixedly connected to the first fixed frame 1111 and the rotating frame 1113. Specifically, the torque motor 1114 includes a second stator 11141, a second rotor 11142 and a support 11143, and one end of the second stator 11141 is fixedly connected to the first On the fixed frame 1111, the other end of the second stator 11141 is fixedly installed on the support 11143, and the second rotor 11142 is fixedly connected to the rotating frame 1113, and the rotation is driven by the electromagnetic torque between the second stator 11141 and the second rotor 11142 Rack 1113 operates. The first position sensor 1115 includes a third stator 11151 and a third rotor 11152, the third stator 11151 is fixedly connected to the second stator 11141, the third rotor 11152 is fixedly connected to the second rotor 11142, and the first position sensor 1115 collects the third stator 1115 The induced potential between 11151 and the third rotor 11152 indirectly measures the rotational position of the torque motor 1114 .

There are two first fixed frames 1111 with the same structure, which are symmetrically and fixedly arranged on both sides of the first frame 111 respectively.

The second frame 112 includes a second fixed frame 1121 . The second fixed frame 1121 is movably fixed on the base of the frame unit 11 . There are two second fixed frames 1121 , which are symmetrically fixed on both sides of the second frame 112 .

The scanning hole 113 is located in the middle of the rack unit 11 for the examinee to enter and exit. The diameter of the scanning hole 113 reaches more than 700mm, so that subjects of various shapes can pass through smoothly. The subject may be a human body, or an animal, a phantom or other types of subject.

The first display unit 12 is fixed on the frame unit 11 . Specifically, the first display unit 12 is fixed on the rack unit 11 through the first fixed frame 1111 of the rack unit 11, and by adjusting the position of the first fixed frame 1111 on the base of the rack unit 11, the second A display unit 12 is at the position of the rack unit 11 . The first imaging unit 12 is an X-ray tomographic imaging unit. It can be understood that, through the rotary motion of the rotating frame 1113 , the imaging chain components of the first imaging unit 12 can be driven to rotate along the axis of the scanning hole 113 of the dual-mode fusion medical imaging system 10 .

The second display unit 13 is fixedly disposed on the frame unit 11 , and the second display unit 13 and the first display unit 12 are spaced side by side. Specifically, the second display unit 13 is arranged on the frame unit 11 through the second fixed frame 1121, and by adjusting the position of the second fixed frame 1121 on the base of the frame unit 11, the position of the second display unit 13 can be changed. In rack unit 11 position. It can be understood that by adjusting the positions of the first imaging unit 12 and the second imaging unit 13 on the frame unit 11, the imaging centers of the first imaging unit 12 and the second imaging unit 13 are on the same horizontal line to ensure The image acquisition coordinate systems of the first display unit 12 and the second display unit 13 are unified.

The first imaging unit 12 includes an X-ray source module 121 , an X-ray detector module 122 , a first electronics module 123 , a data transmission module 124 and a slip ring module 125 .

The X-ray source module 121 includes an X-ray tube 1211 , a beam collimator 1212 and a high voltage power supply 1213 . X-ray tube 1211 is used to emit X-ray source. The line beam collimator 1212 is connected in signal with the X-ray tube 1211 for receiving the X-ray source. The high-voltage power supply 1213 is electrically connected to the X-ray tube 1211 for providing high-voltage power supply. In this embodiment, the X-ray tube 1211 has a large heat capacity, and the high-voltage power supply 1213 can provide an adjustable power supply with a voltage of 70kV-150kV and a current of 50mA-300mA for the X-ray tube 1211 to use.

The X-ray detector module 122 is used to capture the X-ray source while converting the X-photons into visible light and converting the visible light into electrical current signals. The X-ray detector module 122 includes a plurality of X-ray detector units (not shown in the figure), and the X-ray detector units are arranged in an arc shape with the outgoing focal point of the X-ray tube 1211 as the center of a circle. The X-ray detector unit is made of rare-earth ceramic material with shorter afterglow, which can capture more X-photons per unit time.

The first electronic module 123 is electrically connected with the X-ray detector module 121 and is used for processing the current signal and converting the current signal into first image information. Specifically, the first electronics module 123 is electrically connected to the X-ray source module 121 . The first electronic module 123 includes multiple sub-modules with the same function to realize the collection, amplification, analog/digital conversion, and parallel/serial conversion of current signals. The processing core of the first electronic module 123 adopts an ASIC chip, so as to reduce the volume of the module and improve integration and stability.

The data transmission module 124 includes a transmitting end 1241 and a receiving end 1242 for transmitting the first image information to the image unit 15 . The transmitting end 1241 is fixed on the rotating frame 1113 . One end of the transmitting end 1241 is electrically connected to the first electronic module 123 for receiving the first image information and sending it to the receiving end 1242 . The receiving end 1242 and the transmitting end 1241 are fixedly arranged on the first fixed frame 1111 opposite to each other. One end of the receiving end 1242 is electrically connected to the image unit 15 for transmitting data to the image subsystem 15 through capacitive coupling, radio frequency or optical transmission.

The slip ring module 125 includes a multi-turn loop 1251 , a first interface unit 1252 and a second interface unit 1253 for transmitting power and control signals to the first display unit 12 . The first interface unit 1252 is fixedly arranged on the first fixed frame 1111 . One end of the first interface unit 1252 is electrically connected to the peripheral power supply module (not shown) and the control unit 14, and the other end is in slidable contact with the multi-turn loop 1251, and is used to transmit the control signals of the peripheral power supply and the control unit 14 from the second A fixed frame 1111 is transferred to a multi-turn loop 1251 . The second interface unit 1253, one end of which is electrically connected to the multi-turn loop 1251, and the other end is electrically connected to the corresponding unit of the rotating frame 1113, for receiving the peripheral power from the multi-turn loop 1251 and the control of the control unit 14 signal, and transmit peripheral power and control signals to the corresponding units on the rotating frame 1113. In this embodiment, the corresponding units are specifically the X-ray source module 121 , the X-ray detector module 122 , the first electronics module 123 , and the transmitting end 1241 of the data transmission module 124 .

The second imaging unit 13 includes a gamma photon detector module 131 , a second electronics module 132 and a processing module 133 .

The gamma photon detector module 131 is composed of multiple detector units 1311 surrounding the subject. The detector unit 1311 has a three-layer structure, including a crystal array 13111 , a light guide 13112 and a photoelectric conversion device 13113 in sequence. The gamma photon detector module 131 is electrically connected to the control unit 14, and is used for collecting gamma photons radiated from the subject and converting the gamma photons into electrical signals to form detection events. The crystal array 13111 is a two-dimensional array composed of multiple scintillation crystal units of the same size, and the scintillation crystal units are made of crystal material LYSO (but not limited to LYSO).

The second electronic module 132 is composed of a plurality of second electronic module units (not shown) electrically connected to the photoelectric conversion device 13113 . The second electronics module 132 is used for amplifying and analog/digital converting the detection events output by the gamma photon detector module 131, converting the detection signal of the gamma photon pair, corresponding position information and time information into digital signals.

The processing module 133 is electrically connected to the second electronic module 132 and the image unit 15 , and is used to process the digital signal to generate the second image information, and transmit the second image information to the image unit 15 .

The control unit 14 includes a main controller 141 and a control computer 142 electrically connected to the main controller 141 . The control unit 14 includes a main controller 141 and a control computer 142 electrically connected to the main controller 141 . The main controller 141 is composed of at least a processor, a memory, and several communication interface units. Wherein, the communication interface includes one or more of a serial port, an Ethernet port, a CAN interface, etc., and is used to realize each controlled connection between the main controller 141 and the control computer 142, the first display unit 12, and the second display unit 13. communicate between units. The control computer 142 includes a set of operation interfaces for control and display, and realizes all human-computer interaction functions.

The main controller 141 is electrically connected to the second interface unit 1253 for transmitting control signals from the first fixed frame 1111 to corresponding units on the rotating frame 1113 through the second interface unit 1253 . It can be understood that the high-voltage power supply 1213 receives the control signal from the main controller 141 and the power of the peripheral power supply subsystem through the second interface unit 1253 to adjust the output of X-rays. At the same time, the high-voltage power supply 1213 feeds back the working state information of the X-ray source to the main controller 141 through the second interface unit 1253 . The X-ray detector module 122 is opposite to the X-ray tube 1211 and the line beam collimator 1212 of the X-ray source module 121, and the X-ray emitted by the X-ray tube 1211 passes through the subject after being collimated by the line beam collimator 1212, and the rest The X-rays are captured by the X-ray detector module 122 and converted by the first electronic module 123 into high-speed digital signals capable of reflecting structural information of the subject, that is, first image information. The first image information is then transmitted to the image unit 15 through the transmitting end 1241 and the receiving end 1242 . In this embodiment, the first image information is a computed tomography projection image.

The main controller 141 is also electrically connected to the second electronic module 132 and the processing module 133, the main controller 141 receives instructions from the control computer 142, starts or stops the acquisition action of the second electronic module 132, and performs the processing on the processing module 133. Parameter configuration, and detection and collection from the second electronics module 132 and the control processing module 133, so that the processing module 133 can perform coincidence analysis on the digital signal from the second electronics module 132, collect valid coincidence events, and eliminate false coincidence and random According to the event, the second image information is generated, and the second image information is transmitted to the image unit 15 . In this embodiment, the second image information is gamma photon pair coincidence event information.

The main controller 141 is also electrically connected to the second stator 11141 for controlling the rotation of the torque motor 1114 . The main controller 141 is also electrically connected to the third stator 11151 for collecting information from the first position sensor 1115 . It can be understood that the first position sensor 1115 indirectly measures the rotational position of the torque motor 1114 by collecting the induced potential between the third stator 11151 and the third rotor 11152 and is acquired by the main controller 141 .

The image unit 15 is electrically connected to the receiving end 1242 and the processing module 133 . The image unit 15 is used to reconstruct, register and fuse the first image information and the second image information. Image unit 15 is to adopt a single image processor or a plurality of image processors combined, and its implementation can be but not limited to as follows: a single image processor is a single DSP chip under FPGA control, and a plurality of processors combined It is an array composed of multiple DSP chips under the control of FPGA. A single image processor is a single-core CPU or a multi-core CPU, and multiple processors combined are a multi-core CPU or several multi-core CPUs. A single image processor is a general-purpose computational graphics processor under the control of the CPU, and the combined multiple processors are an array composed of several computational graphics processors under the control of the CPU.

The diagnostic bed unit 16 is electrically connected to the main controller 141, and is controlled by the main controller 141 to realize lifting. The diagnostic bed unit 16 includes a bed board 161 , a lifting column 162 , a rail base 163 , a diagnostic bed controller 164 , a second position sensor 165 and a third position sensor 166 . The bed board 161 is made of carbon fiber material, which can support the body weight of the examinee with little deformation of the bed board and can block X-rays as little as possible. The lifting column 162 is fixedly connected to the bed board 161 and has a lifting motor 1621 for driving the bed board 161 to move vertically. The rail base 163' carries the lifting column 162 and has a horizontal motor 1631 for driving the bed board 161 and the lifting column to move horizontally. The diagnostic bed controller 164 is fixedly installed inside the lifting column 162, and is electrically connected to the main controller 141, the lifting motor and the horizontal motor, and is used to control the horizontal movement of the bed board 161 and the vertical movement of the lifting column. The second position sensor 165 is fixedly connected with the horizontal motor 1631 for positioning the horizontal position of the bed board 161 ; and the third position sensor 166 is fixedly connected with the lifting motor 1621 for positioning the vertical height of the bed board 161 .

The main controller 141 is also electrically connected to the second position sensor 165 for collecting information of the second position sensor 165 . The main controller 141 is also electrically connected to the diagnostic bed controller 164 for controlling the horizontal movement and lifting movement of the diagnostic bed unit 16 , and at the same time, collects and feeds back information from the second position sensor 165 and the third position sensor 166 .

Please refer to FIG. 10 , which is a schematic flowchart of a medical imaging method for dual-mode fusion provided by an embodiment of the present invention, and the specific steps are as follows:

Step S10: Establish coordinates based on the diagnostic bed unit 16.

Step S20: Positioning the first display unit 12 and positioning the second display unit 13 .

Establish the coordinates based on the diagnostic bed unit 16 as the reference coordinates, adjust the position of the first imaging unit 12 on the rack unit 11 and adjust the position of the second imaging unit 13 on the rack unit 11, so that the first imaging unit 12 The imaging center of the imaging unit 12 and the imaging center of the second imaging unit 13 are on the same horizontal line, thus structurally ensuring that the imaging centers of the first imaging unit 12 and the second imaging unit 13 are strictly registered, avoiding as much as possible Registration error due to different imaging coordinate systems.

Step S30: Control the first display unit 12 and the second display unit 13 through the control unit 14, and generate first image information and second image information respectively.

Please refer to FIG. 11 , which is a flow chart for generating the first image information and the second image information provided by the embodiment of the present invention, and the specific steps include:

Step S31 : setting the working parameters of the first display unit 12 and the second display unit 13 through the control unit 14 . The operator inputs parameters through the control computer 142 of the control unit 14. After the parameters are packaged at the bottom layer of the control computer 142, they are transmitted to the main controller 141 through the communication interface on the control unit 14. The main controller 141 analyzes the parameters and communicates The interface is forwarded to the functional modules of the first display unit 12 and the second display unit 13 ; the configuration result of the working parameters is fed back to the control computer 142 through the main controller 141 .

Step S32: Setting the scanning range of the subject through the control unit 14 . The operator plans the length of the part of the human body to be examined along the horizontal movement direction (axial direction) of the diagnostic bed unit 16 through the display and control interface of the control computer 142, and the main controller 141 maps the length to the first imaging unit 12 and the second imaging unit 12 respectively. The imaging unit 13 determines the moving range of the diagnostic bed unit 16 and determines the scanning starting position of the diagnostic bed unit 16 .

Step S33: the control unit 14 controls the movement of the diagnostic bed unit 16, and the first imaging unit 12 performs data collection according to preset working parameters to generate first image information. The scan start command is sent by the main controller 141 to control the diagnostic bed unit 16 to move to the initial position of the first imaging unit 12; the diagnostic bed unit 16 continues to move from the initial position, while the first imaging unit 12 imaging chain Continuously collect exposure and projection data according to the set working mode, and transmit the collected data to the image unit 15 through the data transmission module 124 for subsequent software processing.

Step S34: the control unit 14 controls the movement of the diagnostic bed unit 16, and the second imaging unit 13 performs data collection according to preset working parameters to generate second image information. After the imaging process of the first imaging unit 12 ends, the main controller 141 sends the imaging and scanning start instruction of the second imaging unit 13 to control the diagnostic bed unit 16 to move to the first waiting area of the second imaging unit 13. The imaging position is stopped, and then the gamma photon detector module 131 of the second imaging unit 13 is started to collect gamma photons. The collected data is processed by the second electronic module 132, and then transmitted to the image unit 15 through the processing module 133 for further processing. Subsequent software processing work.

In the above steps, after the imaging of the first imaging unit 12 and the second imaging unit 13 is completed, the diagnostic bed unit 16 is moved to the next position to be developed, and the above step S30 is repeated until the data of the entire set scanning range is completed. acquisition, the entire scanning process is terminated.

Step S40: Reconstruct the first image information and the second image information through the image unit 15 . A beam hardening correction step for the first image information is also included before the reconstruction of the first image information is completed. Image reconstruction is carried out based on the first image information and the second image information collected by the first imaging unit 12 and the second imaging unit 13 respectively, wherein the first image information needs to be corrected by the image unit before reconstruction , the second image information is the initial reconstruction and has not been registered by software.

Step S50 : register the reconstructed first image information and second image information through the image unit 15 .

Please refer to FIG. 12 , which is a flow chart of registering the reconstructed first image information and second image information provided by the embodiment of the present invention, including the following steps:

Step S51: Initially register the reconstructed first image information and second image information. The first software registration is performed on the reconstructed first image information and the second image information, and the registration parameters are mainly used for attenuation correction of the second image information.

Step S52: performing attenuation correction on the second image information after the initial registration based on the attenuation correction factor obtained from the first image information after the initial registration. Utilize the first image information after initial registration to generate an attenuation correction factor, and perform attenuation correction on the coincident event data of the second image information based on the obtained attenuation correction factor, so as to improve the positioning accuracy and image contrast of the second imaging unit 13 .

Step S53: performing secondary image reconstruction on the attenuation-corrected second image information. Secondary image reconstruction is performed on the attenuation-corrected coincident event data of the second imaging unit 13 .

Step S54: re-register the second image information obtained through the secondary image reconstruction and the reconstructed first image information. The reconstructed second image information after attenuation correction is re-registered with the reconstructed first image information to obtain more accurate registration parameters.

Please refer to Figure 13 for a flowchart of image registration. Please refer to Figure 13a. The image registration unit is a component of the image unit, including four relatively independent modules of geometric transformation, image interpolation, similarity measurement and optimization. Let f(x) represent the first image information, m(x) represent the second image information, T(x) represent the geometric transformation parameter, and T(m(x)) represent the geometric transformation parameter T(x), which is used to convert The second image information space is mapped to the first image information space. The processing of the image registration unit can be understood as an iterative processing flow. Specifically include the following steps:

Step S501: The image unit 15 inputs the first image information and the second image information, which are denoted as f(x) and m(x) respectively.

Step S502: Set initial registration parameters through the image unit 15 .

Step S503: Perform interpolation on the second image information m(x) with a lower spatial resolution.

Step S504: The image unit 15 calculates the mutual information similarity function of the first image information and the second image information under the initial registration parameters.

Step S505: The image unit 15 calculates the geometric transformation parameters for the next step through an optimization method based on gradient descent until the mutual information similarity function of the first image information and the second image information reaches a maximum value, and the iteration is terminated.

Step S506: The image unit 15 outputs the final precise registration parameter T ^* (x).

Step S60: The image unit 15 fuses the registered first image information and the second image information.

Please refer to FIG. 14 , which is a flow chart of fusing the registered first image information and second image information provided by the embodiment of the present invention, including the following steps:

Step S61: performing wavelet decomposition on the re-registered first image information and second image information. Firstly, the wavelet transform-based algorithm is used to decompose the re-registered first image information and second image information at multiple levels, and each decomposition layer generates four sub-images LL, HL, LH, and HH, which represent the images respectively. Low-frequency components, high-frequency components in the horizontal direction, high-frequency components in the vertical direction, and high-frequency components in the diagonal direction. Divide the high-frequency sub-image into 3×3 or 5×5 sub-blocks, and perform statistical analysis on each sub-block image to calculate its regional variance.

Step S62: Determine the wavelet decomposition coefficients of the fused image. Different fusion rules are used for the low-frequency components and high-frequency components to determine the wavelet decomposition coefficients of the fused image, that is, the low-frequency components adopt the fusion rule that takes the larger absolute value of the corresponding point, and the weighted fusion rule assigns a higher value to the sub-block with a larger regional variance. A large weighting coefficient can be used to obtain the wavelet pyramid decomposition of the fused image.

Step S63: performing inverse wavelet transform to obtain a fused image of the first image information and the second image information.

The medical imaging system with dual-mode fusion described above precisely fixes the first imaging unit 12 and the second imaging unit 13 on the rack unit 11, and adjusts the first imaging unit 12 and the second imaging unit 13 so that the first The imaging centers of the imaging unit 12 and the second imaging unit 13 are on the same horizontal line, which ensures that the image acquisition coordinate systems of the first imaging unit 12 and the second imaging unit 13 are unified; while adopting a unified control unit 14, Make the imaging time interval of the first imaging unit 12 and the second imaging unit 13 as short as possible to reduce the influence of the involuntary movement of the subject's body on the image registration; then the collected first image information and the second The image information is transmitted to the image unit 15, and the image is reconstructed, and then the reconstructed first image information and the second image information are registered twice, which improves the registration accuracy and greatly improves the subsequent image fusion quality.

The above description is only a preferred embodiment of the present invention, and does not limit the present invention in any form. Although the present invention has been disclosed as above with preferred embodiments, it is not intended to limit the present invention. Anyone familiar with this field Those skilled in the art, without departing from the scope of the technical solution of the present invention, may use the technical content disclosed above to make some changes or modify them into equivalent embodiments with equivalent changes, but as long as they do not depart from the technical solution of the present invention, the Technical Essence Any simple modifications, equivalent changes and modifications made to the above embodiments still fall within the scope of the technical solution of the present invention.

Claims (14)

1. a medical image system for bimodulus fusion, is characterized in that, comprising:

Rack unit, comprising:

Base;

First frame, comprising:

First fixed frame, is fixed on described base;

Outer ring spring bearing, comprise the first mutually corresponding stator and the first rotor, described first stator is fixed on described first fixed frame;

Rotary frame, described rotary frame is arranged on described first fixed frame by described the first rotor;

Torque motor, is fixedly connected on described first fixed frame and described rotary frame; And

Primary importance sensor, is fixedly connected on described torque motor, for gathering the position of rotation of described torque motor; And

Second frame, comprises the second fixed frame, and described second fixed frame is two, is fixed on rack unit base movably;

First visualization unit, be fixedly installed in described first frame, described first visualization unit is x-ray tomography visualization unit;

Second visualization unit, be fixedly installed in described second frame, be set up in parallel before and after described second visualization unit and described first visualization unit, and the imaging center point of described first visualization unit and described second visualization unit imaging center point are on same level line, described second visualization unit is positron radionuclide visualization unit;

Control unit, be electrically connected at described primary importance sensor, described first visualization unit and described second visualization unit, for gathering the positional information of described torque motor and controlling described first visualization unit and generate the first image information and described second visualization unit generates the second image information, described first image information is computerized tomography projected image, and described second image information is that γ photon is to meeting event information;

Elementary area, is electrically connected at described first visualization unit and the second visualization unit, for receiving described first image information and described second image information, and described first image information and described second image information are rebuild, registration and fusion calculation; And

Diagnostic bed unit, is electrically connected at described control unit, moves horizontally and elevating movement by described control unit control realization, and wherein, described x-ray tomography visualization unit comprises:

X-ray source module, for providing X-ray;

X-ray detector module, for catching described x-ray source, converts X-ray to visible ray simultaneously, and converts described visible ray to the signal of telecommunication;

First electronics module, is electrically connected with described X-ray detector module, for the treatment of the described signal of telecommunication, and converts the described signal of telecommunication to described first image information;

Slip ring modules, is electrically connected at described x-ray source module and described control unit, for described ray tomography unit transferring electric power and control signal; And

Data transmission module, for described first image information being transferred to described elementary area by medium, described slip ring modules comprises:

Multi-turn circuit, is fixedly installed on the inner ring of described rotary frame around ground;

First interface unit, be fixedly installed on described first fixed frame, its one end and peripheral power supply module and described control unit are electrically connected, the other end and described multi-turn circuit slidingly contact, for the control signal of peripheral power supply and described control unit is transferred to described multi-turn circuit from described first fixed frame; And

Second interface unit, its one end and described multi-turn circuit are electrically connected, and the corresponding units of the other end and described rotary frame is electrically connected, for the control signal of described peripheral power supply and described control unit being transferred to the corresponding units of described rotary frame.

2. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described torque motor, comprise the second stator, the second rotor and bearing, described second stator one end is fixedly connected on described first fixed frame, the other end is fixed on described bearing, and described second rotor is fixedly connected with described rotary frame.

3. the medical image system of bimodulus fusion according to claim 2, it is characterized in that, described primary importance sensor, comprise the 3rd stator and third trochanter, described 3rd stator is fixedly connected with described second stator, described third trochanter is fixedly connected with described second rotor, and described primary importance sensor is for gathering the position of rotation of described torque motor.

4. the medical image system that merges of bimodulus according to claim 1, is characterized in that, described medium is the capacitance signal of described first modulate image information, radiofrequency signal or optical signal.

5. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described x-ray source module, comprising:

X-ray tube, launches x-ray source;

Beam collinmator, is fixedly connected with described X-ray tube, for filtering unnecessary X-ray; And

High voltage power supply, is electrically connected with described X-ray tube, for providing heater current and high voltage power supply for described X-ray tube, and controls X-ray generation.

6. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described X-ray detector module comprises multiple X-ray detector unit, described multiple X-ray detector unit with described X-ray tube go out line focus for the center of circle be arcuation arrangement.

7. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described data transmission module, comprising:

Transmitting terminal, is fixedly installed on described rotary frame, and its one end is electrically connected at described first electronics module, for launching described first image information;

Receiving terminal, rectify with described transmitting and be fixedly installed on over the ground on described first fixed frame, its one end is electrically connected at described elementary area, for receiving described first image information, and described first image information is transferred to described elementary area.

8. the medical image system of bimodulus fusion according to claim 3, it is characterized in that, described positron radionuclide visualization unit comprises:

γ photon detector module, for gathering person under inspection's internal radiation γ photon out, and becomes the signal of telecommunication by described γ photon conversion, forms detection event;

Second electronics module, is all electrically connected with described γ photon detector module and described control power supply, forms digital signal for carrying out process to described detection event;

Processing module, is all electrically connected with described second electronics module and described elementary area, generates described second image information, and described second image information is transferred to described elementary area for processing described digital signal.

9. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described diagnostic bed unit, comprising:

Bed board;

Lifting column, is fixedly connected on described bed board, has lifting motor, vertically moves for driving described bed board;

Guiderail base, carries described lifting column, has horizontal motor, moves in the horizontal direction for driving described bed board and described lifting column;

Second position induction apparatus, is fixedly connected with described horizontal motor, for locating the horizontal level of described bed board;

3rd position sensor, is fixedly connected with described lifting motor, for locating the vertical height of described bed board; And

Diagnostic bed controller, be fixedly installed on the inside of described lifting column, and be electrically connected at master controller, described lifting motor and described horizontal motor, horizontal direction for controlling described bed board moves and the vertical direction of described lifting column moves, and gathers and feeds back described second position sensor and described 3rd position sensor information.

10. the medical image system of bimodulus fusion according to claim 8, it is characterized in that, described control unit comprises:

Master controller; And

Computer for controlling, described computer for controlling and described master controller are electrically connected;

It is electrical that described master controller is connected to described second interface unit, for control signal is transferred to described multi-turn circuit by described second interface unit from described first fixed frame;

Described master controller is also electrically connected at described second stator, for controlling the rotation of described torque motor;

Described master controller is also electrically connected at described 3rd stator, for gathering the information of described primary importance sensor;

Described master controller is also electrically connected at described second electronics module and described processing module, for the instruction according to described computer for controlling, controls described second electronics module and described processing module, to generate described second image information.

The medical image system that 11. bimodulus according to claim 1 merge, is characterized in that, described elementary area is the multiple image processors adopting single image processor or combination.

The medical image system that 12. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is the single dsp chip under FPGA controls, and multiple processors of described combination are the array that the multiple dsp chips under FPGA controls are formed.

The medical image system that 13. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is a monokaryon CPU or multi-core CPU, and multiple processors of described combination are a multi-core CPU or several multi-core CPUs.

The medical image system that 14. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is a general-purpose computations type graphic process unit (GPU) under CPU controls, and multiple processors of described combination are the array that several general-purpose computations type graphic process unit (GPU) under CPU controls form.