CN102920470B - The medical image system that bimodulus merges and method - Google Patents
The medical image system that bimodulus merges and method Download PDFInfo
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Abstract
The medical image system that bimodulus merges, comprising: rack unit; First visualization unit; Second visualization unit, is fixedly installed on rack unit before and after the first visualization unit and the second visualization unit side by side, and imaging center point and the second visualization unit imaging center point of the first visualization unit are on same level line; Control unit, is electrically connected at the first visualization unit and the second visualization unit, generates the first image information and the second visualization unit generates the second image information for controlling the first visualization unit; Elementary area, is electrically connected at the first visualization unit and the second visualization unit, for rebuilding the first image information and the second image information, registration and fusion; Diagnostic bed unit, is electrically connected at control unit, and controlled unit controls realizes moving horizontally and elevating movement.Present invention also offers the medical imaging procedure that a kind of bimodulus merges.The medical image system that bimodulus provided by the invention merges improves image registration accuracy, improves image co-registration quality.
Description
Technical field
The present invention relates to a kind of medical imaging field, particularly relate to medical image system and the method for the fusion of a kind of bimodulus.
Background technology
Positron radionuclide imaging technique (PET) can provide the function image of human metabolism, but PET signal to noise ratio and spatial resolution are all very low, the hypermetabolism region of the pathological changes of PET image display is difficult to locate accurately, and x-ray tomography video picture (CT) technology imaging clearly, spatial resolution are higher, good reference effect is got in the location that can be focus, but it is poor to the display effect of focus itself.Therefore PET image and CT image can be merged, realize better imaging effect.
At present in Medical image fusion field, be limited to device fabrication and use, the image that the overwhelming majority carries out merging is that different machine obtains.The image that this different machine obtains can not synchronous acquisition, and the coordinate acquisition system of the two is also difficult to carry out unified, and the image registration accuracy of so different imaging pattern is not high, have impact on the quality of fused image.
Summary of the invention
Based on this, be necessary the defect existed for above-mentioned fusion type medical image, the medical image system that the bimodulus providing a kind of registration accuracy higher merges.
The medical image system that bimodulus merges, comprising:
Rack unit, comprising:
Base;
First frame, comprising:
First fixed frame, is fixed on described base;
Outer ring spring bearing, comprise the first mutually corresponding stator and the first rotor, described first stator is fixed on described first fixed frame;
Rotary frame, described rotary frame is arranged on described first fixed frame by described the first rotor;
Torque motor, is fixedly connected on described first fixed frame and described rotary frame; And
Primary importance sensor, is fixedly connected on described torque motor, for gathering the position of rotation of described torque motor; And
Second frame, comprises the second fixed frame, and described second fixed frame is fixed on described base;
First visualization unit, is fixedly installed in described first frame;
Second visualization unit, be fixedly installed in described second frame, be set up in parallel before and after described second visualization unit and described first visualization unit, and the imaging center point of described first visualization unit and described second visualization unit imaging center point are on same level line;
Control unit, be electrically connected at described primary importance sensor, described first visualization unit and described second visualization unit, for gathering the positional information of described torque motor and controlling described first visualization unit and generate the first image information and described second visualization unit generates the second image information
Elementary area, is electrically connected at described first visualization unit and the second visualization unit, for receiving described first image information and described second image information, and described first image information and described second image information are rebuild, registration and fusion calculation; And
Diagnostic bed unit, is electrically connected at described control unit, moves horizontally and elevating movement by described control unit control realization.
The medical imaging procedure that bimodulus merges, comprises the steps: to set up the coordinate being benchmark with described diagnostic bed; Locate described first visualization unit and locate described second visualization unit, realizing structure registration; Described control unit controls described first visualization unit and described second visualization unit, and generates the first image information and the second image information respectively; Wherein, described control unit while described first image information of collection or described second image information, and gathers the positional information of described torque motor and described diagnostic bed unit respectively; Based on described first image information, described second image information and described positional information, rebuild described first image information and described second image information; Registration through rebuild after described first image information and described second image information; Merge described first image information after registration and described second image information.
First visualization unit and the second visualization unit are accurately fixed on rack unit by the medical image system that above-mentioned bimodulus merges, by adjusting the first visualization unit and the second visualization unit, the imaging center of the first visualization unit and the second visualization unit is on same level line, ensure that the image acquisition coordinate system unification mutually of the first visualization unit and the second visualization unit; Adopt unified control unit, optimal control flow process simultaneously, make the time of developing interval of the first visualization unit and the second visualization unit as far as possible short, reduce person under inspection health and not independently to be shifted the impact that image registration is caused; Then the first image information gathered and the second image information are transferred to elementary area, and carry out image reconstruction, again secondary registration is carried out to the first image information after reconstruction and the second image information, improve registration accuracy, greatly improve follow-up image co-registration quality.
Accompanying drawing explanation
The floor map of the medical image system that the bimodulus that Fig. 1 provides for the embodiment of the present invention merges.
The three-dimensional structure diagram of the medical image system that the bimodulus that Fig. 2 provides for the embodiment of the present invention merges.
The three-dimensional exploded view of the medical image system that the bimodulus that Fig. 3 provides for the embodiment of the present invention merges.
The structural representation of the first frame one side that Fig. 4 provides for the embodiment of the present invention.
The structural representation of the partial enlargement of the first frame one side that Fig. 5 provides for the embodiment of the present invention.
The schematic perspective view of the diagnostic bed unit that Fig. 6 provides for the embodiment of the present invention.
The structural representation of the first visualization unit of the medical image system that the bimodulus that Fig. 7 provides for the embodiment of the present invention merges.
The structural representation of the second visualization unit of the medical image system that the bimodulus that Fig. 8 provides for the embodiment of the present invention merges.
The structural representation of the detector cell of the second visualization unit that Fig. 9 provides for the embodiment of the present invention.
The schematic flow sheet of the medical imaging procedure that the bimodulus that Figure 10 provides for the embodiment of the present invention merges.
Generation first image information of medical imaging procedure that the bimodulus that Figure 11 provides for the embodiment of the present invention merges and the schematic flow sheet of the second image information.
First image information of the registration that Figure 12 provides for the embodiment of the present invention after rebuilding and the flow chart of the second image information.
The flow chart of the image registration that Figure 13 provides for the embodiment of the present invention.
The structure chart in the image registration portion that Figure 13 a provides for the embodiment of the present invention.
First image information of fusion after registration that Figure 14 provides for the embodiment of the present invention and the flow chart of the second image information.
Detailed description of the invention
Refer to Fig. 1 ~ Fig. 9.The medical image system 10 that bimodulus merges comprises: rack unit 11, first visualization unit 12, second visualization unit 13, control unit 14, elementary area 15 and diagnostic bed unit 16.
Rack unit 11 comprises base 110, first frame 111, second frame 112 and scanning holes 113.The main body of rack unit 11 is steel construction, or other alloy material with similar strength is formed, and guarantees that frame deformation is minimum.
First frame 111 comprises the first fixed frame 1111, outer ring spring bearing 1112, rotary frame 1113, torque motor 1114 and primary importance sensor 1115.First fixed frame 1111 is fixed on rack unit 11 base.Outer ring spring bearing 1112 comprises the first mutually corresponding stator (not shown) and the first rotor (not shown), and the first stator is fixed on the first fixed frame 1111.Rotary frame 1113 is fixedly installed on the first fixed frame 1111 by the first rotor.Torque motor 1114 is fixedly connected on the first fixed frame 1111 and rotary frame 1113, particularly, torque motor 1114 comprises the second stator 11141, second rotor 11142 and bearing 11143, one end of second stator 11141 is fixedly connected on the first fixed frame 1111, the other end of the second stator 11141 is fixedly mounted on bearing 11143, second rotor 11142 is fixedly connected on rotary frame 1113, drives rotary frame 1113 to operate by the electromagnetic torque between the second stator 11141 and the second rotor 11142.Primary importance sensor 1115 comprises the 3rd stator 11151 and third trochanter 11152,3rd stator 11151 is fixedly connected with the second stator 11141, third trochanter 11152 is fixedly connected with the second rotor 11142, and primary importance sensor 1115 is by the position of rotation of the induced potential indirect inspection torque motor 1114 between collection the 3rd stator 11151 and third trochanter 11152.
First fixed frame 1111 is two, and structure is identical, and symmetry is fixedly installed on the first frame 111 both sides respectively.
Second frame 112 comprises the second fixed frame 1121.Second fixed frame 1121, is fixed on rack unit 11 base movably.Second fixed frame 1121 is two, and symmetry is fixedly installed on the second frame 112 both sides respectively.
Scanning holes 113 is positioned at the centre position of rack unit 11, passes in and out for person under inspection.Scanning holes 113 diameter reaches more than 700mm, so that the person under inspection of various build passes through smoothly.Person under inspection can be human body, also can be the examined object body of animal, body mould or other types.
First visualization unit 12 is fixedly installed on rack unit 11.Particularly, first visualization unit 12 is fixed on rack unit 11 by the first fixed frame 1111 of rack unit 11, by adjusting the position of the first fixed frame 1111 on rack unit 11 base, to change the first visualization unit 12 in the position of rack unit 11.First visualization unit 12 is x-ray tomography visualization unit.Be appreciated that the circumnutation by rotary frame 1113, the scanning holes 113 of the medical image system 10 that the video picture chain part of the first visualization unit 12 can be driven to merge along bimodulus axially does gyration.
Second visualization unit 13 is fixedly installed on rack unit 11, and the second visualization unit 13 and the first visualization unit 12 are set up in parallel spatially.Particularly, the second visualization unit 13 is arranged on rack unit 11 by the second fixed frame 1121, by adjusting the position of the second fixed frame 1121 on rack unit 11 base, to change the second visualization unit 13 in the position of rack unit 11.Be appreciated that, by adjusting the first visualization unit 12 and the second position of visualization unit 13 on rack unit 11, the imaging center of the first visualization unit 12 and the second visualization unit 13 is on same level line, ensure that the image acquisition coordinate system unification mutually of the first visualization unit 12 and the second visualization unit 13.
First visualization unit 12 comprises x-ray source module 121, X-ray detector module 122, first electronics module 123, data transmission module 124 and slip ring modules 125.
X-ray source module 121 comprises X-ray tube 1211, beam collinmator 1212 and high voltage power supply 1213.X-ray tube 1211 is for launching x-ray source.Beam collinmator 1212 is connected with X-ray tube 1211 signal, for receiving x-ray source.High voltage power supply 1213 and X-ray tube 1211 are electrically connected, for providing high voltage power supply.In the present embodiment, X-ray tube 1211 has larger thermal capacity, and high voltage power supply 1213 can provide the regulated power supply of voltage 70kV-150kV, electric current 50mA-300mA for X-ray tube 1211.
X-ray detector module 122, for catching x-ray source, converts X-ray to visible ray simultaneously, and converts visible ray to current signal.X-ray detector module 122 comprises multiple X-ray detector unit (not shown), X-ray detector unit with X-ray tube 1211 go out line focus for the center of circle be arcuation arrangement.X-ray detector unit is made up of rare-earth ceramic material, and twilight sunset is shorter, can catch more X-ray within the unit interval.
First electronics module 123 is electrically connected with X-ray detector module 121, for the treatment of current signal, and converts current signal to first image information.Particularly, the first electronics module 123 is electrically connected with x-ray source module 121.First electronics module 123 comprises the identical submodule of multichannel function, realizes the collection to current signal, amplification, analog/digital conversion and parallel/serial conversion.First electronics module 123 processes core and adopts dedicated IC chip, to reduce module volume, improves integrated level and stability.
Data transmission module 124 comprises transmitting terminal 1241 and receiving terminal 1242, for the first image information is transferred to elementary area 15.Transmitting terminal 1241 is fixedly installed on rotary frame 1113.Transmitting terminal 1241 one end is electrically connected at the first electronics module 123, for receiving the first image information, and sends to receiving terminal 1242.Receiving terminal 1242 and transmitting terminal 1241 are fixedly installed on the first fixed frame 1111 just over the ground.Receiving terminal 1242 one end is electrically connected at elementary area 15, for data are delivered to image subsystems 15 by the mode of Capacitance Coupled, radio frequency or optical transport.
Slip ring modules 125 comprises multi-turn circuit 1251, first interface unit 1252 and the second interface unit 1253, for the first visualization unit 12 transferring electric power and control signal.First interface unit 1252, is fixedly installed on the first fixed frame 1111.One end of first interface unit 1252 and peripheral power supply module (not shown) and control unit 14 are electrically connected, the other end slidably contacts with multi-turn circuit 1251, for the control signal of peripheral power supply and control unit 14 is transferred to multi-turn circuit 1251 from the first fixed frame 1111.Second interface unit 1253, its one end and multi-turn circuit 1251 are electrically connected, the corresponding units of the other end and rotary frame 1113 is electrically connected, for receiving the control signal of peripheral power supply from multi-turn circuit 1251 and control unit 14, and peripheral power supply and control signal are transferred to the corresponding units be positioned on rotary frame 1113.In the present embodiment, corresponding units is specially the transmitting terminal 1241 of x-ray source module 121, X-ray detector module 122, first electronics module 123 and data transmission module 124.
Second visualization unit 13 comprises γ photon detector module 131, second electronics module 132 and processing module 133.
γ photon detector mould 131 is made up of the multiple detector cells 1311 around person under inspection, and detector cell 1311 is three-decker, comprises crystal array 13111, photoconduction 13112 and electrooptical device 13113 successively.γ photon detector module 131 is electrically connected at control unit 14, for gathering person under inspection's internal radiation γ photon out, and γ photon conversion is become the signal of telecommunication, forms detection event.The two-dimensional array that crystal array 13111 is made up of the scintillation crystal unit of multiple same size, scintillation crystal unit is prepared from by crystalline material LYSO (but being not limited to LYSO).
Second electronics module 132 is made up of the multiple second electronics modular unit (not shown) being electrically connected on electrooptical device 13113.Second electronics module 132 is amplified for the detection event exported γ photon detector mould 131, analog/digital conversion, and detectable signal right for γ photon, corresponding positional information and temporal information are converted to digital signal.
Processing module 133 and the second electronics module 132 and elementary area 15 are all electrically connected, and generate the second image information, the second image information is transferred to elementary area 15 for processing digital signal.
The computer for controlling 142 that control unit 14 comprises master controller 141 and is electrically connected with master controller 141.The computer for controlling 142 that control unit 14 comprises master controller 141 and is electrically connected with master controller 141.Master controller 141 at least comprises processor, internal memory and several communications interface units on composition.Wherein, communication interface comprises one or more of serial ports, Ethernet interface, CAN interface etc., communicates between master controller 141 with each controlled unit such as computer for controlling 142, first visualization unit 12 and the second visualization unit 13 for realizing.Computer for controlling 142 comprises a set of for the operation interface controlled and show, and realizes all people's machine interactive function.
Master controller 141 and the second interface unit 1253 are electrically connected, for control signal to be transferred to the corresponding units rotary frame 1113 from the first fixed frame 1111 by the second interface unit 1253.Be appreciated that high voltage power supply 1213 receives the control signal of autonomous controller 141 and the electric power of peripheral supplied for electronic system by the second interface unit 1253, the output of X-ray is regulated.High voltage power supply 1213 feeds back the work state information of x-ray source to master controller 141 by the second interface unit 1253 simultaneously.X-ray detector module 122 is relative with beam collinmator 1212 with the X-ray tube 1211 of x-ray source module 121, the X-ray sent by X-ray tube 1211 penetrates person under inspection after beam collinmator 1212 collimates, remaining X-ray is caught by X-ray detector module 122, the high-speed digital signal that can reflect person under inspection's structural information is converted to, i.e. the first image information through the first electronics module 123.First image information by transmitting terminal 1241 and receiving terminal 1242, transfers to elementary area 15 again.In the present embodiment, the first image information is computerized tomography projected image.
Master controller 141 is also electrically connected at the second electronics module 132 and processing module 133, master controller 141 accepts the instruction from computer for controlling 142, start or stop the collection action of the second electronics module 132, parameter configuration is carried out to processing module 133, and detect, collect from the second electronics module 132 and control treatment module 133, realize processing module 133 and analysis is met to the digital signal from the second electronics module 132, collect and effectively meet event, reject vacation to meet and random coincidence event, to generate the second image information, and the second image information is transferred to elementary area 15.In the present embodiment, the second image information is that γ photon is to meeting event information.
Master controller 141 is also electrically connected at the second stator 11141, for the rotation of control moment motor 1114.Master controller 141 is also electrically connected at the 3rd stator 11151, for gathering the information of primary importance sensor 1115.Be appreciated that primary importance sensor 1115 is obtained by master controller 141 by the position of rotation of the induced potential indirect inspection torque motor 1114 between collection the 3rd stator 11151 and third trochanter 11152.
Elementary area 15 is electrically connected at receiving terminal 1242 and processing module 133.Elementary area 15 for rebuilding the first image information and the second image information, registration and fusion.Elementary area 15 is the multiple image processors adopting single image processor or combination, its implementation can be, but not limited to as described below: single image processor is the single dsp chip under FPGA controls, and multiple processors of combination are the array that the multiple dsp chips under FPGA controls are formed.Single image processor is a monokaryon CPU or multi-core CPU, and multiple processors of combination are a multi-core CPU or several multi-core CPUs.Single image processor is a general-purpose computations graphic process unit under CPU controls, and multiple processors of combination are the array of several computational graphic process unit composition under CPU controls.
Diagnostic bed unit 16 is electrically connected at master controller 141, and main controller 141 control realization is elevated.Diagnostic bed unit 16 comprises bed board 161, lifting column 162, guiderail base 163, diagnostic bed controller 164, second position induction apparatus 165 and the 3rd position sensor 166.Bed board 161 adopts carbon fibre material to make, and can support the body weight of person under inspection and bed board deformation is less, and stop X-ray that can be as far as possible few.Lifting column 162, is fixedly connected on bed board 161, has lifting motor 1621, vertically moves for driving bed board 161.Guiderail base 163, carrying lifting column 162, having horizontal motor 1631, moving in the horizontal direction for driving bed board 161 and lifting column.Diagnostic bed controller 164, is fixedly installed on the inside of lifting column 162, and is electrically connected at master controller 141, lifting motor and horizontal motor, and the horizontal direction for controlling bed board 161 moves and the vertical direction of lifting column moves.Second position induction apparatus 165, is fixedly connected with horizontal motor 1631, for locating the horizontal level of bed board 161; And the 3rd position sensor 166, be fixedly connected with lifting motor 1621, for locating the vertical height of bed board 161.
Master controller 141 is also electrically connected at second position sensor 165, for gathering the information of second position sensor 165.Master controller 141 is also electrically connected at diagnostic bed controller 164, for controlling moving horizontally and elevating movement of diagnostic bed unit 16, meanwhile, gathering and feeding back second position sensor 165 and the 3rd position sensor 166 information.
Refer to Figure 10, the schematic flow sheet of the medical imaging procedure that the bimodulus provided for the embodiment of the present invention merges, concrete steps are as follows:
Step S10: the coordinate that to set up with diagnostic bed unit 16 be benchmark.
Step S20: locate the first visualization unit 12 and location the second visualization unit 13.
Set up with diagnostic bed unit 16 coordinate that is benchmark as reference coordinate, adjust the position of the first visualization unit 12 on rack unit 11 and adjustment the second position of visualization unit 13 on rack unit 11, the imaging center of the first visualization unit 12 and the second visualization unit 13 imaging center is made to be on same level line, so structurally ensure the imaging center rigid registrations of the first visualization unit 12 and the second visualization unit 13, avoid the registration error caused because imaging coordinate system is different as much as possible.
Step S30: control the first visualization unit 12 and the second visualization unit 13 by control unit 14, and generate the first image information and the second image information respectively.
Refer to Figure 11, generation first image information provided for the embodiment of the present invention and the flow chart of the second image information, concrete steps comprise:
Step S31: arranged by the running parameter of control unit 14 to the first visualization unit 12 and the second visualization unit 13.Operator are by computer for controlling 142 input parameter of control unit 14, parameter is after the encapsulation of computer for controlling 142 bottom, by the communications interface transmission on control unit 14 to master controller 141, resolved by master controller 141 pairs of parameters, and be forwarded to the functional module of the first visualization unit 12 and the second visualization unit 13 by communication interface; Computer for controlling 142 is fed back to by the configuration result of master controller 141 running parameter.
Step S32: arranged by the sweep limits of control unit 14 couples of persons under inspection.Operator move horizontally the length of direction (axial direction) along diagnostic bed unit 16 by planning human body position to be checked, computer for controlling 142 aobvious control interface, this length is mapped as by master controller 141 respectively need the scope of movement at the first visualization unit 12 and the second visualization unit 13 times diagnostic bed unit 16, and determines diagnostic bed unit 16 scanning starting position.
Step S33: control unit 14 controls diagnostic bed unit 16 and moves, the first visualization unit 12 carries out data acquisition according to the running parameter pre-set, to generate the first image information.Send scanning initial order by master controller 141, control diagnostic bed unit 16 and move to the first visualization unit 12 original position; Diagnostic bed unit 16 is persistent movement from this original position, first visualization unit 12 imaging chain continues to carry out exposing and projection data acquisitions according to the working method of setting simultaneously, and the data of collection are passed to elementary area 15 by data transmission module 124 and carry out follow-up software processes work.
Step S34: control unit 14 controls diagnostic bed unit 16 and moves, the second visualization unit 13 carries out data acquisition according to the running parameter pre-set, to generate the second image information.After the first visualization unit 12 videograph process terminates, the second visualization unit 13 video picture scanning initial order is sent by master controller 141, control first position to be visualized stopping that diagnostic bed unit 16 moves to the second visualization unit 13, then the γ photon detector mould 131 starting the second visualization unit 13 carries out the collection of γ photon, the data gathered through the process of the second electronics module 132, then are passed to elementary area 15 by processing module 133 and carry out follow-up software processes work.
In above-mentioned steps, after first visualization unit 12 and the second visualization unit 13 video picture terminate, diagnostic bed unit 16 is moved to next position to be visualized, repeat above-mentioned steps S30, until complete the data acquisition of whole setting sweep limits, just stop whole scanning process.
Step S40: rebuild the first image information and the second image information by elementary area 15.The step of the beam hardening correction to the first image information was also comprised before completing reconstruction first image information.The first image information gathered based on the first visualization unit 12 and the second visualization unit 13 and the second image information carry out image reconstruction respectively, wherein, first image information is wanted first complete beam hardening correction work by elementary area before reconstruction, and the second image information be first reconstruction and without software registration.
Step S50: by elementary area 15 registration through rebuild after the first image information and the second image information.
Refer to Figure 12, first image information of registration after rebuilding provided for the embodiment of the present invention and the flow chart of the second image information, comprise the steps:
Step S51: first registration is carried out to the first image information after rebuilding and the second image information.The first image information after rebuilding and the second image information are carried out to the first registration on software, registration parameter is mainly used in the correction for attenuation of the second image information.
Step S52: second image information of correction for attenuation factor pair after first registration obtained based on the first image information after first registration carries out correction for attenuation.Utilize the first image information after first registration to generate the correction for attenuation factor, and carry out correction for attenuation based on the event data that meets of correction for attenuation factor pair second image information obtained, improve location accuracy and the picture contrast of the second visualization unit 13.
Step S53: secondary image reconstruction is carried out to the second image information after correction for attenuation.Secondary image reconstruction is carried out to the event data that meets of the second visualization unit 13 after correction for attenuation.
Step S54: to through secondary image rebuild obtain the second image information and through rebuild after the first image information carry out registration again.Second image information of rebuilding after correction for attenuation and the first image information after rebuilding are carried out registration again, obtains more accurate registration parameter.
Referring to Figure 13, is the flow chart of image registration.Refer to the ingredient that Figure 13 a image registration portion is elementary area, comprise geometric transformation, image interpolation, similarity measurement and optimize these four relatively independent modules.F (x) is made to represent the first image information, m (x) represents the second image information, T (x) represents geometric transformation parameter, T (m (x)) represent with geometric transformation parameter T (x), for by the second image information spatial mappings to the first image information space.The process in image registration portion can be understood as an iterative process flow.Specifically comprise the steps:
Step S501: elementary area 15 inputs the first image information and the second image information, and is designated as f (x), m (x) respectively.
Step S502: initial registration parameter is set by elementary area 15.
Step S503: the second image information m (x) lower to spatial resolution carries out interpolation.
Step S504: elementary area 15 calculates the mutual information similarity function of the first image information and the second image information under initial registration parameter.
Step S505: elementary area 15 by calculating next step geometric transformation parameter based on the optimization method of Gradient Descent, until the mutual information similarity function of the first image information and the second image information reaches maximum, iteration ends.
Step S506: elementary area 15 exports final accuracy registration parameter T
*(x).
Step S60: elementary area 15 merges the first image information after registration and the second image information.
Refer to Figure 14, first image information of fusion after registration provided for the embodiment of the present invention and the flow chart of the second image information, comprise the steps:
Step S61: wavelet decomposition is carried out to the first image information after registration again and the second image information.First the algorithm based on wavelet transformation is adopted to decompose at many levels the first image information after registration again and the second image information, each decomposition layer produces 4 width subimage LL, HL, LH and HH, represents the low-frequency component of image, horizontal direction radio-frequency component, vertical direction radio-frequency component and to angular direction radio-frequency component respectively.High frequency subimage is divided into the sub-block of 3 × 3 or 5 × 5, statistical analysis is carried out to each sub-image and calculates its Local Deviation.
Step S62: the coefficient of wavelet decomposition determining fusion image.Low frequency component and high fdrequency component are adopted respectively to each coefficient of wavelet decomposition of different fusion rule determination fusion image, namely low frequency component adopts corresponding point absolute value to get large fusion rule, Weighted Fusion rule, the sub-block larger to Local Deviation gives larger weight coefficient, and the wavelet pyramid obtaining fusion image decomposes.
Step S63: carry out the fusion image that inverse wavelet transform obtains the first image information and the second image information.
First visualization unit 12 and the second visualization unit 13 are accurately fixed on rack unit 11 by the medical image system that above-mentioned bimodulus merges, by adjusting the first visualization unit 12 and the second visualization unit 13, the imaging center of the first visualization unit 12 and the second visualization unit 13 is on same level line, ensure that the image acquisition coordinate system unification mutually of the first visualization unit 12 and the second visualization unit 13; Adopt unified control unit 14 simultaneously, make the time of developing interval of the first visualization unit 12 and the second visualization unit 13 as far as possible short, reduce person under inspection health and not independently to be shifted the impact that image registration is caused; Then the first image information gathered and the second image information are transferred to elementary area 15, and carry out image reconstruction, again secondary registration is carried out to the first image information after reconstruction and the second image information, improve registration accuracy, greatly improve follow-up image co-registration quality.
The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, although the present invention discloses as above with preferred embodiment, but and be not used to limit the present invention, any those skilled in the art, do not departing within the scope of technical solution of the present invention, make a little change when the technology contents of above-mentioned announcement can be utilized or be modified to the Equivalent embodiments of equivalent variations, in every case be do not depart from technical solution of the present invention content, according to any simple modification that technical spirit of the present invention is done above embodiment, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.
Claims (14)
1. a medical image system for bimodulus fusion, is characterized in that, comprising:
Rack unit, comprising:
Base;
First frame, comprising:
First fixed frame, is fixed on described base;
Outer ring spring bearing, comprise the first mutually corresponding stator and the first rotor, described first stator is fixed on described first fixed frame;
Rotary frame, described rotary frame is arranged on described first fixed frame by described the first rotor;
Torque motor, is fixedly connected on described first fixed frame and described rotary frame; And
Primary importance sensor, is fixedly connected on described torque motor, for gathering the position of rotation of described torque motor; And
Second frame, comprises the second fixed frame, and described second fixed frame is two, is fixed on rack unit base movably;
First visualization unit, be fixedly installed in described first frame, described first visualization unit is x-ray tomography visualization unit;
Second visualization unit, be fixedly installed in described second frame, be set up in parallel before and after described second visualization unit and described first visualization unit, and the imaging center point of described first visualization unit and described second visualization unit imaging center point are on same level line, described second visualization unit is positron radionuclide visualization unit;
Control unit, be electrically connected at described primary importance sensor, described first visualization unit and described second visualization unit, for gathering the positional information of described torque motor and controlling described first visualization unit and generate the first image information and described second visualization unit generates the second image information, described first image information is computerized tomography projected image, and described second image information is that γ photon is to meeting event information;
Elementary area, is electrically connected at described first visualization unit and the second visualization unit, for receiving described first image information and described second image information, and described first image information and described second image information are rebuild, registration and fusion calculation; And
Diagnostic bed unit, is electrically connected at described control unit, moves horizontally and elevating movement by described control unit control realization, and wherein, described x-ray tomography visualization unit comprises:
X-ray source module, for providing X-ray;
X-ray detector module, for catching described x-ray source, converts X-ray to visible ray simultaneously, and converts described visible ray to the signal of telecommunication;
First electronics module, is electrically connected with described X-ray detector module, for the treatment of the described signal of telecommunication, and converts the described signal of telecommunication to described first image information;
Slip ring modules, is electrically connected at described x-ray source module and described control unit, for described ray tomography unit transferring electric power and control signal; And
Data transmission module, for described first image information being transferred to described elementary area by medium, described slip ring modules comprises:
Multi-turn circuit, is fixedly installed on the inner ring of described rotary frame around ground;
First interface unit, be fixedly installed on described first fixed frame, its one end and peripheral power supply module and described control unit are electrically connected, the other end and described multi-turn circuit slidingly contact, for the control signal of peripheral power supply and described control unit is transferred to described multi-turn circuit from described first fixed frame; And
Second interface unit, its one end and described multi-turn circuit are electrically connected, and the corresponding units of the other end and described rotary frame is electrically connected, for the control signal of described peripheral power supply and described control unit being transferred to the corresponding units of described rotary frame.
2. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described torque motor, comprise the second stator, the second rotor and bearing, described second stator one end is fixedly connected on described first fixed frame, the other end is fixed on described bearing, and described second rotor is fixedly connected with described rotary frame.
3. the medical image system of bimodulus fusion according to claim 2, it is characterized in that, described primary importance sensor, comprise the 3rd stator and third trochanter, described 3rd stator is fixedly connected with described second stator, described third trochanter is fixedly connected with described second rotor, and described primary importance sensor is for gathering the position of rotation of described torque motor.
4. the medical image system that merges of bimodulus according to claim 1, is characterized in that, described medium is the capacitance signal of described first modulate image information, radiofrequency signal or optical signal.
5. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described x-ray source module, comprising:
X-ray tube, launches x-ray source;
Beam collinmator, is fixedly connected with described X-ray tube, for filtering unnecessary X-ray; And
High voltage power supply, is electrically connected with described X-ray tube, for providing heater current and high voltage power supply for described X-ray tube, and controls X-ray generation.
6. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described X-ray detector module comprises multiple X-ray detector unit, described multiple X-ray detector unit with described X-ray tube go out line focus for the center of circle be arcuation arrangement.
7. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described data transmission module, comprising:
Transmitting terminal, is fixedly installed on described rotary frame, and its one end is electrically connected at described first electronics module, for launching described first image information;
Receiving terminal, rectify with described transmitting and be fixedly installed on over the ground on described first fixed frame, its one end is electrically connected at described elementary area, for receiving described first image information, and described first image information is transferred to described elementary area.
8. the medical image system of bimodulus fusion according to claim 3, it is characterized in that, described positron radionuclide visualization unit comprises:
γ photon detector module, for gathering person under inspection's internal radiation γ photon out, and becomes the signal of telecommunication by described γ photon conversion, forms detection event;
Second electronics module, is all electrically connected with described γ photon detector module and described control power supply, forms digital signal for carrying out process to described detection event;
Processing module, is all electrically connected with described second electronics module and described elementary area, generates described second image information, and described second image information is transferred to described elementary area for processing described digital signal.
9. the medical image system of bimodulus fusion according to claim 1, it is characterized in that, described diagnostic bed unit, comprising:
Bed board;
Lifting column, is fixedly connected on described bed board, has lifting motor, vertically moves for driving described bed board;
Guiderail base, carries described lifting column, has horizontal motor, moves in the horizontal direction for driving described bed board and described lifting column;
Second position induction apparatus, is fixedly connected with described horizontal motor, for locating the horizontal level of described bed board;
3rd position sensor, is fixedly connected with described lifting motor, for locating the vertical height of described bed board; And
Diagnostic bed controller, be fixedly installed on the inside of described lifting column, and be electrically connected at master controller, described lifting motor and described horizontal motor, horizontal direction for controlling described bed board moves and the vertical direction of described lifting column moves, and gathers and feeds back described second position sensor and described 3rd position sensor information.
10. the medical image system of bimodulus fusion according to claim 8, it is characterized in that, described control unit comprises:
Master controller; And
Computer for controlling, described computer for controlling and described master controller are electrically connected;
It is electrical that described master controller is connected to described second interface unit, for control signal is transferred to described multi-turn circuit by described second interface unit from described first fixed frame;
Described master controller is also electrically connected at described second stator, for controlling the rotation of described torque motor;
Described master controller is also electrically connected at described 3rd stator, for gathering the information of described primary importance sensor;
Described master controller is also electrically connected at described second electronics module and described processing module, for the instruction according to described computer for controlling, controls described second electronics module and described processing module, to generate described second image information.
The medical image system that 11. bimodulus according to claim 1 merge, is characterized in that, described elementary area is the multiple image processors adopting single image processor or combination.
The medical image system that 12. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is the single dsp chip under FPGA controls, and multiple processors of described combination are the array that the multiple dsp chips under FPGA controls are formed.
The medical image system that 13. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is a monokaryon CPU or multi-core CPU, and multiple processors of described combination are a multi-core CPU or several multi-core CPUs.
The medical image system that 14. bimodulus according to claim 11 merge, it is characterized in that, described single image processor is a general-purpose computations type graphic process unit (GPU) under CPU controls, and multiple processors of described combination are the array that several general-purpose computations type graphic process unit (GPU) under CPU controls form.
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