CN102908188A - Radio frequency ablation (RFA) catheter system for denervation of renal sympathetic nerves - Google Patents

Radio frequency ablation (RFA) catheter system for denervation of renal sympathetic nerves Download PDF

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CN102908188A
CN102908188A CN 201210313087 CN201210313087A CN102908188A CN 102908188 A CN102908188 A CN 102908188A CN 201210313087 CN201210313087 CN 201210313087 CN 201210313087 A CN201210313087 A CN 201210313087A CN 102908188 A CN102908188 A CN 102908188A
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ablation
catheter
structure
handle
control
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CN 201210313087
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CN102908188B (en )
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宋治远
杨攀
钟理
王子洪
廖新华
仝识非
舒茂琴
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中国人民解放军第三军医大学第一附属医院
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Abstract

The invention provides a radio frequency ablation (RFA) catheter system for denervation of sympathetic nerves in renal arteries. The system comprises an ablation catheter, a control handle, a guiding catheter and an ablation generating device and can be provided or not provided with an independent guiding catheter control handle, wherein the ablation catheter is formed by a catheter body section and an ablation section from near end to far end in sequence. The system is characterized in that the front end of the catheter body section also comprises a controllable bending section; the controllable bending section is connected with the control handle by the catheter body section; at least two independent structures are installed on the ablation section; and an ablation head is installed on at least one independent structure. The system can carry out multipoint ablation simultaneously, monitors the ablation effect during operation in real time, and has better mechanical stability.

Description

肾脏去交感神经射频消融导管系统 Renal sympathetic denervation radiofrequency ablation catheter system

技术领域 FIELD

[0001] 本发明涉及一种医疗器械,具体是一种用来治疗高血压病、通过介入的方式进入肾动脉内阻断肾脏交感神经的射频消融导管系统。 [0001] The present invention relates to a medical instrument, particularly for a treatment of hypertension, radiofrequency ablation catheter system into the renal artery within the kidney sympathetic nervous blocked by intrusively.

背景技术 Background technique

[0002] 高血压是临床常见病、多发病,根据最新的数据推算,中国高血压患者群已超过2亿,且呈发病人数逐年增加,发病年龄逐渐提前趋势。 [0002] Hypertension is a common disease, frequently-occurring disease, according to the latest data projections, the Chinese population has more than 200 million patients with hypertension, and the number of cases was increasing year by year, age of onset gradually advancing trend. 高血压导致的心、脑、肾等重要脏器并发症,有很高的致死率与致残率,严重危害着人类健康。 Heart, brain, kidneys and other vital organs complications caused by high blood pressure, have a high mortality and morbidity, serious harm to human health. 我国约有3000〜4000万顽固性高血压患者,而未来伴随着人口老龄化及肥胖症、糖尿病人的增加,顽固性高血压的患者数量将进一步增加,给社会、家庭、个人带来极大的负担。 China has about 3000~4000 Wan patients with resistant hypertension, and the future along with the aging population and obesity, diabetes increases the number of patients with resistant hypertension will increase further, to bring great social, family, personal burden. 目前无较好的顽固性高血压治疗方法,开拓新的非药物治疗手段,弥补当前药物疗法的不足从而简单、安全、有效地控制血压刻不容缓。 Currently no better method of refractory hypertension, open up new non-drug treatment, to make up for the current lack of drug therapy so simple, safe and effective control of blood pressure without delay.

[0003] 大量研究证实,过度激活的交感神经系统与高血压的形成与进展密切相关,其中,肾脏交感神经系统特别是最靠近肾动脉壁的肾交感传出和传入神经,被认为是高血压始动及维持的重要因素。 [0003] Numerous studies confirm that over-activation of the sympathetic nervous system is closely related to the formation and progression of hypertension, where the kidney sympathetic nervous system, particularly the renal artery wall closest to the renal sympathetic efferent and afferent nerves are considered high blood pressure and initiating an important factor to sustain. 针对这一机制,国外学者提出了通过导管消融肾动脉交感神经治疗顽固性高血压这一新的高血压治疗策略。 In response to this mechanism, foreign scholars put forward by sympathetic renal artery catheter ablation treatment of refractory hypertension this new hypertension treatment strategies.

[0004] 2009年,Krum等在导管消融肾脏交感神经治疗顽固性高血压研究(SymplicityHTN-1)中首先用Ardian公司生产Symplicity消融导管对45例顽固性高血压患者实施肾脏去交感神经射频消融术,证实这项新技术的简单、安全,降压效果出现早,并能长期保持。 Hypertension Treatment Study refractory renal sympathetic [0004] 2009, Krum et ablation (SymplicityHTN-1) is first produced by Ardian Symplicity ablation catheter 45 patients with resistant hypertension renal sympathetic denervation embodiment radiofrequency ablation catheter , confirmed that this new technology is simple, safe, antihypertensive effect appeared early, and maintain long-term. 在长达2年的追踪观察中,未发现下降的血压重新增高,且肾功保持稳定。 In the follow-up observation up to 2 years and found no drop in blood pressure again increased, and renal function remained stable. 国外多个中心正在进行或已完成经皮导管肾脏去交感神经治疗的临床研究多达十余项,已完成或正在进行的临床试验结果令人鼓舞,该项技术可望成为高血压治疗领域革命性的突破。 Clinical research centers abroad more ongoing or completed percutaneous renal sympathetic denervation catheter treatment up to more than 10, have been completed or ongoing clinical trial results are encouraging, the technology is expected to become a revolution in the treatment of hypertension field of breakthrough.

[0005] 此项技术在国内的应用尚处于起步探索阶段,该产品还未进入国内市场,阜外医院于2012年2月12日在国内经特批试用Symplicity消融导管对4例顽固性高血压患者成功实施了手术。 [0005] application of this technology in China is still at the initial stage of exploration, the product has not yet entered the domestic market, Fu Wai Hospital on February 12, 2012 in the country with special approval trial Symplicity catheter ablation four cases of resistant hypertension He was successfully carried out the operation. 国内有几家医院于2011年用心脏射频消融导管实施了数例肾脏去交感神经治疗,疗效目前尚未见文献报道。 There are several hospitals in the country in 2011 with a cardiac radiofrequency catheter ablation implemented a number of cases of renal sympathetic denervation therapy, efficacy has yet to see reported.

[0006] US 2011/0264075 Al公开了一种用于肾去交感神经的射频消融导管,Ardian公司生产的此种导管虽然在国外临床中有一定的应用,但是也存在明显的不足。 [0006] US 2011/0264075 Al discloses a method for radio frequency ablation of renal sympathetic denervation catheter, although Ardian produced such a catheter has certain clinical applications in foreign countries, but there are obvious deficiencies. 首先该种导管仅能进行单点消融,由于肾去交感神经的射频消融治疗一般是绕肾动脉一周进行6-8个点的螺旋形消融,因此Ardian公司的此种导管需要消融6_8次,手术时间比较长。 The first kind of catheter ablation of only a single point, since the renal sympathetic denervation radiofrequency ablation is generally performed spirally around 6-8 points ablation of renal artery one week, so Ardian such companies require ablation catheter 6_8 times, surgery a long time. 针对Ardian公司的消融导管不能进行多点消融的问题,US 2012/0116392 AUUS 2012/0029510Al、CN 201110117776. 8、CN201110327772. 2通过在多条电极杆上分别设置射频消融电极从而到达多点同时消融的目的,CN 102198015A则通过在一条螺旋形的电极杆上按照预定位置安装多个射频电极来实现多点同时消融,虽然上述设计在一定程度上实现了肾动脉内多点同时消融,但是由于射频消融电极与血管壁贴合不够紧,使得射频消融电极在消融时容易移动,而造成消融范围过大,给患者造成不必要的损伤;为了使得多个射频消融电极同时紧密贴附血管壁,US 2012/0101413A1采用了在旋形的电极杆内设置扩张球囊的方案,通过在球囊中充入液体可以使得射频消融电极与血管壁紧密贴附,但是球囊扩张时肾血流会被阻断,如果消融时间较长容易导致肾缺血,而引起不必要的并发症;为了避免肾 Ardian's not possible for multi-point ablation catheter ablation problem, US 2012/0116392 AUUS 2012 / 0029510Al, CN 201110117776. 8, CN201110327772. 2 are provided by a plurality of rod electrodes radiofrequency ablation electrode to reach the multi-point simultaneous ablation object, CN 102198015A mounted through the plurality of RF electrodes according to a predetermined position of the electrode rod a helical multi-point simultaneous ablation is achieved, although the above design to achieve a multi-point within the renal artery in the same time a certain degree of ablation, radiofrequency ablation but because and an electrode bonded to the vessel wall is not tight enough, so that the RF ablation electrodes easily move during the ablation, the ablation range caused by excessive, unnecessary damage to the patient; for such plurality of radio frequency ablation electrodes while tightly attaching the vessel wall, US 2012 / 0101413A1 uses expandable balloon disposed in the electrode rod-shaped rotation scheme, by the balloon may cause the charged liquid radiofrequency ablation electrode closely attached to the vessel wall, but when the balloon of renal blood flow will be blocked If ablation longer easily lead to renal ischemia, which leads to unnecessary complications; kidney in order to avoid 血流被阻断US 2012/0029512 Al将球囊替换成了金属丝网球,虽然解决了肾血流被阻断的问题,但是操作上远没有球囊方便;此外人的肾动脉走行变异较大,上述这些多个射频消融电极的设计方案很难在肾动脉走行发生变异时应用,因此限制了肾去交感神经治疗的人群。 Blood flow is blocked US 2012/0029512 Al balloon replaced with wire tennis, solves the problem of renal blood flow is blocked, but the operation is far from easy balloon; moreover human renal artery course variation greater the plurality of RF ablation electrode designs are difficult to apply when the renal artery course variation occurs, thus limiting populations renal sympathetic denervation therapy. 其次Ardian公司的単射频电极导管以及上述多个射频消融电极导管的导向控制不够准确,使得适用人群偏小,因此不能很好满足临床要求。 Second Ardian's radiolabeling RF lead electrodes and said plurality of radio frequency catheter ablation pilot control is not accurate enough, so that the intended audience is small, and therefore can not meet the clinical requirements. 再次,Ardian公司的単射频电极导管以及上述多个射频消融电极的导管都很难对消融的效果进行实时监测,因此很难在术中进行疗效检测,使得患者二次手术风险増加。 Again, the company radiolabeling Ardian RF lead and the plurality of radiofrequency catheter ablation electrodes are difficult to effect real-time monitoring of the ablation, it is difficult to detect efficacy in surgery, such patients to increase in the risk of reoperation. 以前的消融导管主要采用线控结构控制,但是线控结构不易操作,结构也较复杂,本发明提供了ー种导管控制系统,结构更简便。 Previous ablation catheter wire structure control mainly, but the wire structure to operate, and also more complex structure, the present invention provides catheters ー control system, the structure is more simple.

发明内容 SUMMARY

[0007] 本发明的目的是提供了一种可实现同时多点消融、可术中实时监测消融阻断效果、机械稳定性更好的肾脏去交感神经消融导管系统 [0007] The object of the present invention is to provide a multi-point can be achieved ablation, the ablation may be monitored in real time intraoperative blocking effect, a better mechanical stability to renal sympathetic ablation catheter system

[0008] 为了实现上述目的,本发明提供了ー种消融导管系统,消融导管、导引导管、控制手柄及消融发生装置,其中消融导管由下往上依次由导管体段和消融段组成;其中 [0008] To achieve the above object, the present invention provides an ablation catheter system ー species, ablation catheters, guiding catheter, the control handle and the ablation generator, wherein the ablation catheter from the bottom to top by the catheter body section and the ablation segments; wherein

[0009] 所述导管体段与控制手柄相连; [0009] The catheter body section and is connected to the control handle;

[0010] 所述消融段安装有独立结构,独立结构至少为两个,所述独立结构的近端相连,所述消融段至少有ー个独立结构上安装有消融头;所述消融头通过导线、导管、微波天线或光纤与控制手柄上的能量交換接头相连,所述能量交换接头通过导线、导管、微波天线或光纤与消融发生装置相连; [0010] The ablation segment attached independent structure, at least two separate structures, a proximal end connected to said separate structure, the ablation section has at least one ー ablation head is mounted on a separate structure; the ablation head by wires , catheter, or microwave energy on the antenna and the optical fiber connector is connected to the exchange control handle, said energy exchange means connected through a wire connector, a catheter, optical fiber or microwave antenna ablation occurred;

[0011] 所述导引导管通过牵拉或推送一端附着在导引导管头端上,另一端由手柄控制的导引丝控制弯曲;或所述导引导管(7)发生顺应性弯曲或预制形变。 [0011] The guide catheter attached to the end of the guide catheter by pulling or pushing the head end, the other end of the control handle controls the guidewire is bent; or the guide catheter (7) is bent or pre-compliance occurrence deformation.

[0012] 所述导管体段(4)的远端还包括与消融段(6)近端连接的可控弯曲段(5);还包括独立设置或者不独立设置的导引导管控制柄。 The distal end [0012] of the catheter body section (4) further comprises a controllable curved section (5) and the ablation segment (6) connected to a proximal end; further comprising independently provided or not provided independently of the guiding catheter handle.

[0013] 进ー步的,所述消融导管或/和导引导管或/和导引导管控制柄或/和控制手柄上还安装有传感器。 [0013] ー step into the ablation catheter and / or guide catheter and / or guide catheter handle and / or further control handle is attached to the sensor.

[0014] 更进一歩的,所述消融导管或/和导引导管或/和导引导管控制柄或/和控制手柄上还安装有传感器。 [0014] More into a ho of the ablation catheter and / or guide catheter and / or guide catheter handle and / or further control handle is attached to the sensor.

[0015] 所述独立结构之间在近端相连,两个独立结构之间包括三种形式:两个独立结构的远端连接为一体而构成消融段头端;或者两个独立结构远端彼此独立相互分离;或者两个独立结构的中间部分连接在一起,远端再相互分离。 [0015] The separate structure between the proximal end is connected between the two separate structures comprising three forms: two separate distal structure integrally connected to form an ablation tip section; another distal structure or two separate independently from each other; or intermediate portion connecting together two separate structures, a distal end and then separated from each other.

[0016] 当导引导管为消融导管形变提供支点吋,导引导管的头部设置与血管相通的斜孔或/和侧槽。 [0016] When the guide catheter to provide a fulcrum for the ablation catheter inch deformation, the guide catheter is provided with a head inclined hole communicating vessels and / or side groove.

[0017] 当独立结构的远端连接为一体而构成消融段头端时,导引导管头端设置缩ロ结构或者堵头,导引导管的头部侧壁上设置侧槽;当独立结构彼此独立相互分离时,导引导管的头端或头部侧壁上设置斜孔。 [0017] When the distal end integrally connected to an independent structure to form an ablation section when the head end, the head end of the guide catheter is provided ro condensing structure or plug is provided on the head side of the groove side wall of the guide catheter; to each other when an independent structure independence from each other, the head end of the guide catheter sidewall on the head or inclined hole.

[0018] 当独立结构的中间部分连接在一起,远端再相互分离时,导引导管的头端或头部侧壁设置与血管相通的斜孔,斜孔(74)之后导引导管的侧壁上再设置侧槽。 [0018] When the intermediate portion of the separate structure are connected together, the distal end and then separated from each other, the head or head end of the vessel side wall in communication with the guide catheter inclined hole, after slant holes (74) of the guide duct then set side groove wall.

[0019] 当导引导管不为消融导管形变提供支点时,独立结构设置预制形变。 [0019] When the guide catheter ablation catheter not provided fulcrum deformation, deformation prefabricated structure is provided independently.

[0020] 还包括可控弯曲段设置预制形变。 [0020] A controlled deflection section further comprises a pre-set deformation.

[0021] 所述独立结构上或/和可控弯曲段上还设置有检测电极;或所述消融头兼用于发放或/和接收电脉冲,为了检测消融阻断效果,消融头上、消融头周围的独立结构上或可控弯曲段上可以设置电脉冲发放或/和接收电极,电极本身可兼具有发放和接受电脉冲的能力。 Further provided on the structure or on a separate [0021] / curved sections and controllable detection electrode; or the ablation head and for dispensing or / and receives electrical pulses, in order to detect the effect of ablation of the ablation head, the ablation head issuing electrical pulses may be provided and / or receiver electrodes, and the electrode itself may have the ability to issue and receive electrical pulses on a separate structure around the upper curved sections or controllable. 对于仅有一个电极的情况,优选将电极置于消融头上或消融头周围的独立结构上,在消融完成后,将电极置于消融点靠肾脏侧,发放适当的电脉冲,如果该电脉冲仍能引起血压升高,则说明消融未完全阻断肾脏交感神经。 For the case where only one electrode is preferably an ablation electrode in the head or ablation on a separate structure around the head, after completion of the ablation, the ablation electrode was placed on the kidney-side point, issuing an appropriate electrical pulse, electric pulse if the It can still cause high blood pressure, then the renal sympathetic ablation is not completely blocked. 对于多个电极的情况,优选将多个电极间隔一定距离设置,此时除可以采用仅有一个电极时的消融阻断效果的检测方法外,还可以让至少两个电极形成接受和发放电脉冲的电极对,通过在消融开始前和消融完成后将至少两个电极组成的电极对置于消融损伤的前后两侧,通过比较消融术前和术后电极接收电脉冲信号之间的变化也可以判断消融效果,如果该信号未发生变化,说明肾动脉周围的肾脏交感神经仍可跨过消融损伤处传导电脉冲,即消融未完全阻断肾脏交感神经。 For the case where a plurality of electrodes, the plurality of electrodes is preferably arranged at a distance, can be employed in addition to this case only a method for detecting an outer blocking effect when the ablation electrode may also be formed so that at least two electrodes to accept and release electrical pulse a pair of electrodes, by ablation before the start and after completion of the ablation electrode at least two electrodes placed on the front and rear sides of the ablation lesion, by comparing change between before and after ablation electrode receives the electrical pulse signal may be Analyzing the ablation effect, if the signal does not change, indicating sympathetic nerves around the renal artery renal ablation lesion across the still conduct electrical impulses, i.e., ablation of renal sympathetic not completely blocked. 上述两种方法均可以作为检测肾脏去交感神经术是否成功的方法,这些检测方法有助于在术中及时判断消融效果,避免二次手术。 Both methods can be used as a method to detect whether renal sympathetic denervation surgery successful, these tests help determine intraoperative ablation effect in time to avoid the second surgery. 此外某些类型的消融头本身也可以兼作为发放或/和接收电脉冲信号的电极,例如射频消融电极头、液冷灌注射频电极头等。 Furthermore some types of ablation head itself may also serve as an electrode issuance and / or receive electrical pulse signals, such as radio frequency ablation electrode tip, liquid-cooled top irrigated RF electrodes. 当然技术人员也可以根据消融导管的功能不设置电极。 Of course, the art may be no electrode ablation catheter according to function. 在设置多个电极时,可在消融头前后的独立结构上分别设置至少一个电极,或者可将至少一个电极设置在消融头上、消融头周围的独立结构上而将另外的电极设置在可控弯曲段与肾动脉接触的地方,抑或将消融头作为电脉冲信号的发放或接收电极而将电极设置在消融头周围的独立结构上或可控弯曲段与肾动脉接触的地方。 When a plurality of electrodes, at least one electrode may be provided on separate structures, respectively, before and after the ablation head, or at least one electrode may be disposed on a separate structure ablation head, and the head around the ablation electrode disposed further controllable where contact with the curved section of the renal artery, or the ablation head as a payment received electrical pulse signal or the electrode in contact with the curved section or a controllable renal artery electrode disposed on a separate structure where the ablation head around. 电极的形状可以是多样的,例如可以是环状包绕独立结构,也可以是半环状,只包绕独立结构与血管接触的部分,还可以突起的小点状;但无论如何,电极的形状应有助于其与血管接触。 The shape of the electrode may be varied, for example, may be wrapped independently a cyclic structure, and may be semi-annular, surrounding only a part of the structure in contact with the vessel independently, may also be a small dot-like protrusions; but in any case, the electrode which should help shape contact with the vessel. 电极将接收的信号优选通过消融导管内的导线传到控制手柄上,并优选最终传到消融发生装置。 Electrode signal is preferably received through a wire within the catheter ablation transmitted on the control handle, and preferably eventually passes an ablation generator.

[0022] 所述导引导管的尾部侧壁上还设有用于连接注射器或注液装置进行血管内注药或注射血管内造影剂的开孔,或通过导引导管末端开口与注射器或/和注液装置相连进行血管内注药或/和注射血管内造影剂;或/和所述导引导管末端设置连接接头,连接接头与注射器、注液装置、消融导管或控制手柄连接。 [0022] The tail portion is also provided on the side wall of the guide catheter connected to a syringe or the injection means for injection or hole injection intravascular angiographic agent, or with the injector tip opening through the guide catheter and / or injection means connected for injection and / or angiographic contrast material injection intravascular; or / and the guide catheter tip connection joint is provided, connecting the syringe adapter, the injection means, ablation catheter control handle or connector.

[0023] 所述消融导管或/和导引导管制造时通过选用不同硬度的材料,或者是通过选择性的减少或/和增加部分导管的内部结构或/和管壁的结构。 [0023] The ablation catheter and / or reduce and / or increase the internal structure or / and the wall and the use of different durometer material manufactured through the guide catheter, or by selective portion of the catheter.

[0024] 所述消融导管或/和导引导管上标记刻度,以指示消融导管或/和导引导管进入血管的深度以及在超声或X射线影像设备下间接测量人体结构的长度、宽度;消融导管或/和导引导管上设置不同的显影标记用于在超声或X射线影像设备下区分消融导管或/和导引导管;或/和各独立结构上设置不同的显影标记用于在超声或X射线影像设备下区分不同的独立结构;消融导管或/和导引导管上还设置标记用于在超声或X射线影像设备下区分不同的轴向旋转状态。 [0024] The ablation catheter and / or guide catheter marker on the scale, to indicate the ablation catheter and / or guide catheter into a blood vessel and an indirect measurement of the depth of the anatomy under ultrasound or X-ray imaging device length, width; Ablation catheters and / or guide catheter is provided on the different opaque markers for X-ray or ultrasound imaging equipment to distinguish between the ablation catheter and / or guide catheter; or opaque markers for different settings in the ultrasound / or structure and each independently distinguish between different independent X-ray imaging equipment configuration; ablation catheter and / or guide catheter set markers for X-ray or ultrasound imaging equipment to distinguish between different axial rotation state.

[0025] 消融导管的末端或/和导引导管与控制手柄上端固定,消融导管与环形控制钮上的连接杆相连;控制手柄的下端或下侧面具有能量交换接头,来自消融头的导线、导管、微CN 102908188 A [0025] The tip of the ablation catheter and / or guide catheter with a control handle fixed to an upper end, an annular ablation catheter and the control knob is connected to the connecting rod; the control or the lower side of the lower end of the handle having an energy interchange connections, wires from the head of the ablation catheter , CN 102908188 A micro

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波天线或光纤穿过控制手柄的中心空腔在所述能量交換接头汇集。 Wave antenna or optical center of the cavity through the control handle in the energy exchange joint together.

[0026] 消融导管通过导管体段与控制手柄上端固定,控制手柄的下端或下侧面具有能量交换接头,来自消融头的导线、导管、微波天线或光纤穿过控制手柄在所述能量交換接头汇集。 [0026] The upper end of the ablation catheter through the catheter body and control handle fixing section, the lower end of the control handle or linker energy exchange with the lower side, from the ablation head wires, catheters, fiber optic or microwave antenna through the control handle fitting together of the energy exchange . ·[0027] 所述控制手柄上设置有用于控制导引导管形变的控制钮或控制盘,所述控制钮或控制盘与导向丝连接,通过控制钮的上下移动,或通过控制盘的多向转动实现对可控弯曲段的控制;或/和环形控制钮,所述环形控制钮通过连接杆与牵引丝连接,所述连接杆位于控制手柄中的导向槽内,通过上下移动环形控制钮,实现对独立结构的控制;还包括可防止过度牵拉的缓冲结构。 * [0027] The control handle is provided for controlling the control panel or control buttons deformation guiding catheter, the control or the control panel is connected to the wire, by controlling the vertical movement of the knob, or by a multidirectional control panel controllably rotated to achieve control of the bent section; or / and an annular control knob, said annular control knob through a connecting rod connecting the traction wire, the connecting rod guide slot located in the control handle, the control knob by moving the ring, achieve independent control structures; further comprises a buffer structure prevents excessive pulling.

[0028] 所述导引导管控制柄上设置有用于控制导引导管形变的控制钮或控制盘,所述控制钮或控制盘与导向丝连接,通过控制钮的上下移动,或通过控制盘的多向转动实现对导引导管的控制;所述导引导管控制柄与控制手柄包括可脱槽齿滑动结构,可脱槽齿滑动结构由卡槽、锥柱体凹槽、卡环、卡孔、可压钩状结构和锥柱体突出榫组成,通过可脱槽齿滑动结构进行分拆与结合。 [0028] The guide is provided with a control knob or control panel deformable guide catheter, or the control panel and the control knob connected to the wire, by controlling the vertical movement of the knob, or the control panel on the catheter handle multi achieve control of the rotation of the guide catheter; said guide catheter control handle comprises a handle with detachable teeth slide groove structures, teeth slidably detachable from the slot groove configuration, the groove tapered cylinder, a snap ring, engaging holes Compressible hook structure and pillars projecting tongue cone composition, are split off and be joined by sliding structure tooth groove.

[0029] 所述消融发生装置设有能量输出的接头和传感器信号输入的接头,同时还设有与外接电源相接地接头;所述消融发生装置含有通过进行触屏控制来控制參数以及部分或全部信息能显示在其上的显示器和调节參数的按钮。 [0029] The ablation occurs apparatus provided with a joint connector and a sensor input signal energy output, and also provided with a connector to an external power supply contact; touch screen controlled by a control parameter of the ablation apparatus comprising part occurs, and all information can be displayed or a display and buttons on the control parameter thereof.

[0030] 本发明提供一种可实现同时多点消融、可在线实时监测消融阻断效果、导管制作相对较简单、机械稳定性更好的肾脏去交感神经消融导管系统。 [0030] The present invention may be implemented to provide a multi-point ablation, ablation of online real-time monitoring effect, making the catheter relatively simple, better mechanical stability to renal sympathetic ablation catheter system.

[0031] 由于本发明采用了至少两条独立结构且每条独立结构上均可设置消融头,因此可以实现多点同时消融,缩短了消融时间,进而減少了手术时间、减小了患者的痛苦,此外由于在消融时多条独立结构上的消融头将同时与血管壁接触,可以防止消融头滑动,使得消融时消融头更加稳定,防止了消融时因消融头不稳定造成的正常组织不必要的损伤,減少了消融产生的并发症,使消融过程更安全。 [0031] Since the present invention uses at least two independent and can be disposed on each of the individual structures and the ablation head structure, it is possible to achieve multi-point simultaneous ablation, ablation time is shortened, thereby reducing the operation time, reducing the patient's pain Additionally because the ablation head on a plurality of independent structure while in contact with the vessel wall during ablation, the ablation head slider can be prevented, so that more stable ablation the ablation head against normal tissue ablation due to the ablation head instability unnecessary the damage and reduce complications resulting ablation, the ablation procedures safer. 另外,导引导管有相应的线控结构对其形变进行控制,因此导管具有较好的操控性,能适应不同走行的肾动脉,而且消融导管外加套导引导管来辅助消融导管定位,这样整个消融导管系统在血管内的定位将更准确,防止不必要的损伤,同时也可以使整个消融系统应用于更多的人群。 Further, the guide wire catheter structure with a corresponding control of its deformation, and therefore has good handling of the catheter, can adapt to different traveling of the renal artery and catheter ablation catheter introducer sheath is applied to assist in positioning the ablation catheter, so that the entire positioning the ablation catheter in a blood vessel system will be more accurate and prevent unnecessary damage, but can also be applied to the entire ablation system more people. 此外该设计方案中消融导管避免了复杂的线控结构,使其结构更为简便。 In addition, the design of the ablation catheter to avoid the complexity of wire structure, make its structure more simple. 不仅如此,为了方便在手术中实时监测消融效果,在消融导管上还安装有检测电极以方便及时检测消融效果,避免二次手术风险。 Moreover, in order to facilitate real-time monitoring during surgery ablation effect, in the ablation catheter is also equipped with a detection electrode to facilitate the timely detection ablation effect, to avoid the risk of reoperation.

附图说明[0032] 图I是根据本发明的一个实施方式主要部分的示意图。 BRIEF DESCRIPTION [0032] I is a schematic diagram according to one embodiment of the present invention, a main part of FIG. [0033] 图2是放大的消融段中两个独立结构之间的连接方式的示意图。 [0033] FIG. 2 is a schematic diagram of the connection between the two separate amplified segment of the ablation structure. [0034] 图3是放大的消融段中两个独立结构之间在不同的连接方式下发生形变后的示意图。 [0034] FIG. 3 is an enlarged schematic view of the ablation segment deformation occurs at different connection between two separate structures. [0035] 图4是射频消融电极头在独立结构上不同的设置方式的示意图。 [0035] FIG. 4 is a schematic view of a radio frequency different arrangement of an independent structure on the ablation tip. [0036] 图5是射频消融电极头为射频消融电极头时的示意图。 [0036] FIG. 5 is a schematic view of radiofrequency ablation tip electrode RF ablation head. [0037] 图6是独立结构为两个时消融段的设计简图。 [0037] FIG. 6 is a schematic view of two separate structural design of the ablation segments. [0038] 图7是独立结构为三个时消融段的设计简图。 [0038] FIG. 7 is a structure of three independent segments ablation schematic design. 7[0039] 图8是独立结构为四个时消融段的设计简图。 7 [0039] FIG. 8 is a structure of four independent design schematic ablation segment.

[0040] 图9是独立结构为三个且相互分离时工作状态下的简图。 [0040] FIG. 9 is a diagram of the structure of the independently operating state and separated from each other when the three.

[0041] 图10是独立结构为两至四个时的横截面轮廓简图。 [0041] FIG. 10 is a cross-sectional profile independent structure schematic view when two to four.

[0042] 图11是可控弯曲段为“C”形设计时工作状态下的示意图。 [0042] FIG. 11 is a schematic curved section is controlled in the operating state "C" shaped design.

[0043] 图12、图13、图14、图15是以两条独立结构为例且导引导管能够为消融导管的形变提供支点的情况下,导引导管头部的示意图。 [0043] FIG 12, FIG 13, FIG 14, FIG 15 is a structure as an example a case where two separate and guide catheter to provide a fulcrum for the deformation of the ablation catheter, the guide catheter head of FIG.

[0044] 图16是以远端连接于消融段头端的两条独立结构为例的情况下,导引导管头部的示意图以及消融导管和导引导管工作状态下的示意图[0045] 图17、图18是通过结构设计的方式改变消融导管和导引导管硬度分布的示意图。 [0044] FIG. 16 is a case where the distal end of the ablation segment is connected to the head end of the structure as an example of two separate, guide catheter head and a schematic diagram in schematic catheter and guide catheter ablation working condition [0045] 17, FIG 18 is a schematic view of the catheter and guide catheter to change the hardness distribution of an ablation by means of structural design.

[0046] 图19是通过调整远端连接于消融段头端的独立结构的硬度分布实现设计形变的示意图。 [0046] FIG. 19 is a schematic view of the distal end of the hardness distribution by adjusting the individual structures of the head end of the ablation segment is connected to a deformation to achieve the design.

[0047] 图20是通过调整可控弯曲段的硬度分布实现设计形变的示意图。 [0047] FIG. 20 is controlled by adjusting the hardness of the design to achieve a schematic curved section of the strain distribution.

[0048] 图21是通过调整相互分离的独立结构的硬度分布实现设计形变的示意图。 [0048] FIG. 21 is separated from each other by adjusting the hardness of a schematic configuration of an independent deformation to achieve the design profile.

[0049] 图22、图23是通过调整中间某处连接在一起远端再相互分离的独立结构的硬度分布实现设计形变的示意图。 [0049] FIG. 22, FIG. 23 is connected somewhere in the middle by adjusting the design to achieve a schematic view of the distal end with the strain hardness distribution from each other and then separate and independent structures.

[0050] 图24是导引导管尾部主要结构的示意图。 [0050] FIG. 24 is a schematic view of the main structure of the tail guide catheter.

[0051] 图25是导引导管的线控结构与通过鸡肋样结构促进导引导管形成所需要的形变形态的示意图。 [0051] FIG. 25 is a wire structure and a schematic view of the guiding catheter aspect promoting deformation required guide catheter-like structure formed by the tasteless.

[0052] 图26、图27以及图28是在以线控结构为例的情况下,几种不同类型的控制手柄的 [0052] FIG. 26, FIG. 27 and FIG. 28 is a case where an example of the wire structure, several different types of control handle

主要结构特点的示意图。 A schematic view of the main structural features.

具体实施方式 detailed description

[0053] 下面结合附图和具体实施例,进一步阐述本发明的实施例。 [0053] conjunction with the accompanying drawings and the following specific embodiments, further illustrate the embodiments of the present invention. 这些实施例应理解为仅用于说明本发明的实施例而不用于限制本发明的实施例的保护范围。 These examples should be understood to merely illustrate embodiments of the present invention is not intended to limit the scope of embodiments of the present invention. 在阅读了本发明的实施例记载的内容之后,技术人员可以对本发明的实施例作各种改进或修改,这些等效变化和修饰同样落入本发明的实施例权利要求所限定的范围。 After reading the contents of the embodiments of the invention described, the art can make various improvements or modifications of the embodiments of the present invention, such equivalent variations and modifications are also within the embodiment of the present invention as claimed in claim defined range.

[0054] 图I显示了本发明的具体实施方式中主要的部件。 [0054] Figure I embodiment shows a specific embodiment of the present invention, the main components. 如图I所示,该种肾脏去交感神经消融系统主要由消融导管I、导引导管7、控制手柄2及消融发生装置3组成,根据情况设置或不设置导引导管控制柄27。 As shown in FIG. I, the kind of renal sympathetic denervation ablation catheter ablation system consists of I, 7 guiding catheter, the control handle 2 and 3 consisting of the ablation generator, or may not handle the guide catheter 27 is provided according to the situation. 如图I所示,消融导管I远端(头端)游离,近端(尾端、末端)与控制手柄2相连,消融导管I由近端向远端依次至少由导管体段4和消融段6组成,其中导管体段4的近端(尾端、末端)与控制手柄2相连,消融段6的远端(头端)游离,导管体段前端还可包括可控弯曲段5,根据情况也可以在导管体段4和消融段6之间设置其他的段。 As shown in FIG. I, I ablation catheter distal end (tip) of the free, coupled to the proximal end (tail end) and the control handle 2, an ablation catheter from the proximal to distal sequence I of at least a section of the catheter body and the ablation segment 4 6, of which is connected to the proximal end (tail end) of the catheter body 4 and the control handle section 2, the distal end of the ablation segment 6 (the head end) of the free, front end of the catheter body section may further include a controllable curved section 5, according to the situation other segments may be provided between the catheter body and the ablation segment section 4 6. 优选地,消融导管I各段横截面的外轮廓最好采用圆形或类圆形,消融导管I进入到血管内的各段直径最好相近或相等。 Preferably, the cross section of the ablation catheter I outer contour of each stage is preferably used circular or round, I ablation catheter into a blood vessel diameter in each stage is preferably similar or equal. 消融导管I的长度必须使得消融段6能够顺利到达双侧肾动脉指定的消融部位,一般为50--120cm,且整个消融导管I各段的最大直径优选小于所须经过血管路径中血管的最小内径,消融导管I的直径一般为I. 4-2. 5mm。 I ablation catheter must have a length such that the ablation section 6 can smoothly reach the specified bilateral renal artery ablation site, typically 50--120cm, I and the entire ablation catheter segments is preferably less than the maximum diameter of the blood vessel through the vascular path to be minimal an inner diameter, the diameter of the ablation catheter is generally I I. 4-2. 5mm. 如图I所示,其中导引导管7优选为中空管状结构,首尾两端均设有开口,导引导管7套在消融导管I外能够辅助消融导管I到达指定的消融位置。 FIG I, in which the guide catheter 7 is preferably a hollow tubular structure, and finish ends are provided with an opening, in the guide catheter ablation catheter sheath 7 outside I can assist the ablation catheter ablation I reaches the specified location. 导引导管7的长度必须使得导引导管7能够顺利地引导消融导管I到达双侧肾动脉指定的消融部位,一般为50--120cm,且整个导引导管7各段的最大外径优选小于所须经过血管路径中血管的最小直径,导引导管7的直径一般为I. 4—2. 5mm。 7 the length of the guide catheter must be such that the guide catheter can be smoothly guided 7 I ablation catheter reaches the specified bilateral renal artery ablation site, typically 50--120cm, and the entire guide catheter 7 of each stage is preferably less than the maximum outer diameter the minimum diameter of the vessel to go through the path of blood vessels, the diameter of the guide catheter is typically 7 I. 4-2. 5mm.

[0055] 图2显示了本发明的实施例中消融段6的主要特点。 [0055] FIG. 2 shows the main features of embodiments of the present invention, an ablation segment 6. 如图2所示,消融段6由至少两个独立结构8组成;该独立结构8可以是柱体形、类似柱体形、半圆柱形、锥体形、类似锥体形、弧形等,各独立结构8的长度及横截面尺寸可以相等也可以不等,但优选地,所有独立结构8横截面的外轮廓围成的消融段6横截面的外轮廓最好接近可控弯曲段5横截面的外轮廓。 2, the ablation section 6 of the structure 8 composed of at least two independent; the column 8 may be separate structure shape, similar to the column shape, a semi-cylindrical, conical, pyramidal similar, arcuate, etc., each independently structure 8 the length and cross-sectional dimension may be equal to be unequal, but the cross-sectional outer contour 6 preferably, all of the outer contour of the cross section 8 separate structures surrounded controllable ablation segment preferably near the bent section 5 of the outer contour of the cross section . 如图2A所示,两个独立结构8的远端(头端)连接于消融段头端17(也即消融导管头端);如图2B所示,两个独立结构8相互分离、彼此独立;如图2C所示,两个独立结构8的中间某处连接在一起远端再相互分离,其中连接点18为所述两个独立结构8连接在一起的地方。 2A, two separate structures distal end (head end) 8 is connected to the head end of the ablation segment 17 (i.e., the ablation catheter tip); shown in Figure 2B, two separate independent structures 8 each, independently of one another ; 2C, somewhere in the middle of two separate distal structure 8 are joined together and then separated from each other, wherein the point of attachment 18 to the two separate places structure 8 are connected together. 独立结构8的尾端连于导管体段4前端的可控弯曲段5。 8 is an independent structure attached to the trailing end of the catheter body distal section 4 of the controlled deflection section 5.

[0056] 图3显示了本发明的实施例中独立结构8在不同的两个连接方式下发生形变后的情況。 [0056] FIG. 3 shows the case where the embodiment of the present invention, an independent structure 8 is deformed at two different connections. 其中图3A显示了远端连接于消融段头端17的独立结构8发生形变后的情况,此时独立结构8的中间部分将四散隆起,一般地,以独立结构8的中间或靠近中间处隆起最为明显。 3A shows a distal end which is connected to the case where the individual structures 17 deform ablation segment head end 8, At this time, the independent structure of the intermediate portion 8 of the scattered ridges, generally, intermediate 8 independent structure or near the middle of the ridge the most obvious. 图3B显示了独立结构8相互分离时发生形变后的情况,此时独立结构8将相互远离,一般地,以独立结构8的头端及其附近位置相互远离最为明显。 3B shows the case where the deformation occurs when the structure 8 independently from each other, this case will be far away from each other 8 independent structure, in general, to a position near the head end and away from each other independent structure 8 most obvious. 图3C显示了独立结构8中间某处连接在一起远端再相互分离时发生形变后的情況,此时从连接点18到独立结构8头端的部分将相互远离,一般地,以独立结构8头端及其附近位置相互远离最为明显,从连接点18到独立结构8尾端(末端、远端)之间的部分将四散隆起,一般地,以连接点18到独立结构8尾端之间的部分的中间或靠近中间处隆起最为明显。 FIG 3C shows the case where the individual structures 8 occurs somewhere in the middle is connected with the distal end of each strain was then isolated, this time from the connection point 18 to a separate structural part of the head end 8 remote from each other, in general, in order to separate the structure 8 apart from each other and their end position near the most obvious, to separate from the connection point 18 between the 8 tail moiety (end, a distal end) will be scattered ridges, generally, 18 to be connected to a separate structure between the point 8 of the tail near the middle or intermediate portion of the ridge is most obvious.

[0057] 图4显示了本发明的实施例中射频消融电极头9在独立结构8上不同的设置方式。 [0057] FIG. 4 shows an embodiment of the present invention, radiofrequency ablation tip 9 is independent on the structure of 8 different arrangement. 如图4A所示,至少有ー个独立结构8上设置有射频消融电极头9 ;如图4B、图4C所示,每个独立结构8可以设置不只ー个射频消融电极头9。 4A, at least ー independent structure 8 is provided with radiofrequency ablation tip 9; FIG. 4B, as shown in Figure 4C, the structure of each individual may be provided more than 8 ー radio frequency ablation tip 9. 射频消融电极头9主要用于对肾脏交感神经的消融阻断;射频消融电极头9应是发挥消融作用的原件,优选射频消融电极头9为射频电极头, Radiofrequency ablation tip 9 is mainly used for the ablation of renal sympathetic; radiofrequency ablation electrode head 9 should play a role in the original ablation, radiofrequency ablation electrode head 9 is preferably a radio frequency electrode tip,

[0058] 图5A-C是以两个独立结构8的远端连接于消融段头端17为例,显示了射频消融头9的主要结构特点。 [0058] Figures 5A-C are two independent structures distal to the ablation section 8 is connected to the head end 17 as an example, it shows the main structural features of the head 9 radiofrequency ablation. 图5A显示了纵剖面下的主要结构特点,射频消融电极头包括射频消融电极91,优选地,射频消融电极91略突出于独立结构8的表面O. 05—0. 2mm,以便与血管壁接触。 5A shows a longitudinal section of the main structural features of the RF ablation tip electrode 91 comprises a radio frequency ablation, preferably radiofrequency ablation electrode 91 to separate slightly protruding surface structure 8 O. 05-0. 2mm, so as to contact with the vessel wall . 如图5A所示,走行于独立结构8内的射频导线101将与射频消融电极极91相连,为射频消融电极91提供能量,导线连接点191是射频导线101与射频消融电极91的连接位置。 5A, traveling in a separate structure 8 RF conductor 101 is connected to RF electrode ablation electrode 91, to provide energy for radiofrequency ablation electrode 91, lead wire connection 101, 191 is a radio frequency ablation with radiofrequency electrode 91 of the connection position. 如图5A所示,信号线102与设置在射频消融电极91上或/和邻近射频消融电极91的传感器192相连,用于传输传感器192(图5B示)发送的信号;传感器192可以是不同类型的,例如:温度传感器、阻抗传感器、压カ传感器等;同一类型的传感器192在独立结构8上也可不止ー个(图5是以ー个传感器192作为示例);传感器192对射频消融电极91及人体的參数监控,有助于了解实时情况,及时调整治疗方案。 As shown, the signal line 102 and a radio frequency ablation 5A disposed on the electrode 91 or / and adjacent radiofrequency ablation electrode 91 is connected to sensor 192, sensor 192 for signal transmission (shown in FIG. 5B) is transmitted; sensor 192 may be of different types , for example: a temperature sensor, an impedance sensor, pressure sensor, ka; the same type of sensor 192 on a separate structure 8 may also be more than one ー (FIG. 5 is a ー sensors 192 as an example); radiofrequency ablation electrode sensor 192 91 and parameter monitoring of the human body, helps to understand the real-time situation, timely adjustment of treatment. 图5B及图5C以透视方式显示了射频消融电极头9及其周围独立结构8的主要结构特点。 5B and 5C show radiofrequency ablation tip 9 and its surrounding main structural features of the independent structure 8 in perspective. 如图5B所示,射频消融电极91 (图中斜线表示部分)可以仅包绕半圆柱体的曲侧面而不包绕半圆柱体的平侧面90 ;如图5C所示,射频消融电极91(图中斜线表示部分)可以既包绕半圆柱体的曲侧面也包绕半圆柱体的平侧面90 ;当然射频消融电极91还可根据情况对其包绕的范围进行调整。 5B, radiofrequency ablation electrode 91 (hatched portion in FIG.) May be wrapped around the curved side surface of semi-cylinder only and not surrounding the flat side 90 of the half-cylinders; 5C, radiofrequency ablation electrode 91 (hatched portion in FIG.) may surround either a semi-cylindrical curved side is also semi-cylindrical surrounding flat sides 90; radiofrequency ablation electrode 91 may of course be adjusted according to the situation surrounding its scope. Map

图5E是以两个独立结构8的远端相互分离为例,显示了射频消融头9纵剖面的主要结构特 Figure 5E is a distal end 8 of the two separate structures separated from each other as an example, main structural Laid radiofrequency ablation head 9 is a longitudinal section

9点;其中,图5D显示的是消融头9只包绕半圆柱体的曲侧面而不包绕半圆柱体的平侧面90的情况,图5E显示的是消融头9包绕半圆柱体的曲侧面和半圆柱体的平侧面90的情况。 9; wherein FIG. 5D shows the ablation head 9 surrounding curved semi-cylindrical half-cylinder side without wrapping flat sides of the case 90, Figure 5E shows the ablation head of the half-cylinders 9 wrapped curved sides and flat sides 90 of the semi-cylindrical case. 图5D、图5E所示意的射频消融电极头的设计方案与图5A-C所示意的射频消融电极头的设计方案类似。 5D, a design similar to the design illustrated in FIG. 5E radiofrequency ablation tip with Figures 5A-C are a schematic of the RF ablation tip. 如图5D、图5E所示,独立结构8的远端能够相互远离,类似地,走行于独立结构8内的射频导线101将与射频消融电极91相连,为射频消融电极头9提供能量,导线连接点191是射频导线101与射频消融电极91相连接的位置。 FIG. 5D, FIG 5E, the distal end of structure 8 can be separate away from each, similarly, running in a separate structure 8 RF conductor 101 is connected to the electrode 91 with radiofrequency ablation, radiofrequency ablation tip to provide energy 9, wire RF conductor 191 is connected to point 101 and RF ablation electrode 91 is connected to the position. 如图5D、图5E所示,类似地,信号线102与设置在射频消融电极91上或/和邻近射频消融电极91的传感器192相连,用于传输传感器192发送的信号;类似地,传感器192可以是不同类型的,例如:温度传感器、阻抗传感器、压力传感器等;同一类型的传感器192在独立结构8上也可不止一个(图8是以一个传感器192作为示例);传感器192对射频消融电极头9及人体的参数监控,有助于了解实时情况,及时调整治疗方案。 FIG. 5D, FIG 5E, the Similarly, the signal line 102 is provided with a radio frequency ablation electrodes 91 or / and adjacent radiofrequency ablation electrode 91 is connected to sensor 192, sensor 192 transmits a signal for transmission; similarly, the sensor 192 It may be of different types, for example: a temperature sensor, an impedance sensor, a pressure sensor or the like; the same type of sensor 192 on a separate structure 8 may also be more than one (in FIG. 8 as an example is a sensor 192); a sensor 192 RF ablation electrodes 9 and the head of the body parameter monitoring, help to understand the real-time situation, timely adjustment of treatment. 如图所示,射频消融电极91可以仅包绕半圆柱体的曲侧面而不包绕半圆柱体的平侧面90 ;如图5E所示,射频消融电极91可以既包绕半圆柱体的曲侧面也包绕半圆柱体的平侧面90 ;当然射频消融电极91还可根据情况对其包绕独立结构8的范围进行调整。 As shown, radiofrequency ablation electrode 91 may be wrapped around the curved side surface of semi-cylinder only and not surrounding the flat side 90 of the half-cylinders; 5E, radiofrequency ablation electrode 91 may be either semi-cylindrical curved wrap also semi-cylindrical side surface surrounding the flat sides 90; radiofrequency ablation electrode 91 may of course be adjusted independently of its scope wrap structure 8 according to the situation. 图5仅是以两个独立结构8的远端连接于消融段头端17和远端相互分离为例进行射频消融头9的设计方案说明的,因此图5所示意的射频消融头9的设计方案同样适用于独立结构8的其他连接方式以及多个独立结构8的情况;对于独立结构8的形状不为半圆柱形的情况以及对于消融头9设置位置处的独立结构8的形状有所变化的情况,也可以仿照图5所示意的设计方案进行设计。 Figure 5 shows only two separate structure is distal to the ablation section 8 is connected to the head end 17 and a distal end separated from one another example radiofrequency ablation head design illustrated embodiment 9, thus in Fig. 5 a schematic design of radiofrequency ablation head 9 apply equally to other independent connection structure 8 and 8 a plurality of individual structures; for the shape is not an independent structure 8 and a semi-cylindrical shape of the separate structure 9 is provided at the position of the ablation head 8 varies case, the design may be modeled schematically in FIG. 5 be designed.

[0059] 图6、图7、图8分别简示了独立结构8为两至四个时消融段6的主要结构特点。 [0059] FIG. 6, 7, 8 are schematically illustrated as separate structures 8 two to four ablation section 6 of the main structural features. 图9列举了独立结构8为三个且相互分离时工作状态下的情况。 9 lists the structure of FIG. 8 is a case where independent operation state of three and separated from each other. 图10简示了独立结构8为两至四个时的横截面轮廓。 FIG 10 illustrates a simple structure independently 8 is a cross-sectional profile at two to four.

[0060] 如图6所示,当独立结构8为两个时,最好每个独立结构8上都设有一个射频消融·电极头9。 [0060] As shown in FIG 6, when an independent structure 8 is two, each individual structure 8 preferably has a radiofrequency ablation tip · 9. 如图6A所示,两个独立结构8的远端连接于消融段头端17,两个独立结构8最好等大,每个独立结构8长度优选为13—30mm,两个独立结构8的形变将使得两个独立结构8的中间部分相对隆起,形成类似纺锤形的结构,隆起最明显的地方一般位于独立结构8的中间或靠近中间的位置并将首先接触血管壁,此时射频消融电极头9最好设置于每个独立结构8隆起最明显的地方;每个独立结构8隆起最明显的地方可以不同;各独立结构8的中间隆起最明显的部分长度可以有所不同,此时射频消融电极头9在各独立结构8的设置位置可在同一横截面上或者不在同一横截面上。 6A, the distal end 8 is connected to two separate structures to the head end of the ablation segment 17, 8 is preferably two separate structures like large, the length of each individual structure 8 preferably 13-30mm, two separate structure 8 the deformation structure such that two separate intermediate portions of opposing ridges 8, spindle-like structure is formed, the bulge is generally located where the most significant independent intermediate structure 8 and a position at or near the middle of the first contact with the vessel wall, radiofrequency ablation electrode case head 9 is preferably provided on each individual ridge structure 8 where the most obvious; each independently ridge structure 8 may be different from the most obvious place; each independently of the structure of the intermediate 8 most significant bulge portion length can vary, then RF 9 is provided in the ablation tip position 8 the same configuration independently of each cross section or may not in the same cross-section. 如图6B所示,两个独立结构8相互分离,两个独立结构8的长度最好相等,每个独立结构8长度优选为10—20mm,两个独立结构8的形变将使得两个独立结构8相互远离,一般独立结构8的头端及其附近位置相互远离最为明显并将首先接触血管壁,此时射频消融电极头9最好设置在各独立结构8的头端及其附近位置;若希望消融点在血管的不同横截面上,可使两个独立结构8的长度不相等,或者两个独立结构8的长度相等,但射频消融电极头9在各独立结构8头部的设置位置互不相同。 6B, the two structures 8 independently from each other, the length of two independent structures 8 are preferably equal, the length of each individual structure 8 preferably 10-20mm, two separate structural deformation 8 will cause two separate structures 8 away from each other, generally independent of the structure of a position near the head end 8 and away from each other and the most significant first contact with the vessel wall, radiofrequency ablation tip 9 at this time is preferably disposed at a position near the head end and each independently structure 8; if different desired ablation points in the vessel cross section, allows two independent structures 8 unequal length, or two separate structural length equal to 8, but radiofrequency ablation electrode is provided at a position cross head 9 are each independently of the structure of the head 8 Are not the same. 如图6C所示,两个独立结构8的中间某处连接在一起远端再相互分离,两个独立结构8的长度优选相等,每个独立结构8的长度优选为20—40mm,连接点18最好选择在独立结构8远端到连接点18的部分占整个独立结构8长度30—50%的地方;如图6C所示,两个独立结构8的形变将使得连接点18到独立结构8尾端的部分相对隆起,一般以该部分中间或靠近中间的位置相对隆起最明显,而连接点18到独立结构8头端的部分相互远离,一般以独立结构8的头端及其附近位置相互远离最为明显,此时将有四个位置优先接触血管壁,即两个独立结构8的头端及其附近位置和隆起最明显的地方,最好将射频消融电极头9设置于两个独立结构8的头端及其附近位置,而电极19可设置在中间隆起最明显的地方;若希望消融点在血管的不同横截面上,可使两个独立结构8中连接点18至独立结构8头 Shown, somewhere in the middle of two separate structures 8 are connected together as shown in FIG 6C distal again separated from each other, two separate structural length preferably equal to 8, the length of each individual structure 8 is preferably 20-40mm, the connection point 18 preferably selected 8 point of attachment to the distal end of an independent structure portion 18 of the total length of 8 independent configuration where 30-50%; FIG. 6C, two separate structural deformation such that the connection point 8 of the structure 18 to a separate 8 part of the trailing end of the opposing ridges, generally in the middle of the section or a position near the middle of the opposing ridges most obvious point 18 to a separate structure 8 end portion connected to each other away from the general to the head end and its vicinity of the position independent structure 8 away from each other the most obviously, this case will have four priority position in contact with the vessel wall, i.e. two separate structure and the head end vicinity of the position where the most obvious and ridges 8, preferably RF ablation tip 9 is provided in two separate structure 8 and a position near the head end, the electrode 19 may be disposed in the middle of the raised most obvious place; if desired ablation points different cross section in a blood vessel, can point to the individual structures 18 two separate connection structure 8 8 之间的部分长度不相等,或者两个独立结构8的长度相等,连接点18至独立结构8尾端之间的独立结构8的长度也相等,但射频消融电极头9在各独立结构8头部的设置位置不相同。 Portion between unequal length, or two separate structures 8 of equal length, the length of the connection between the individual structures 8 18 points to a separate tail structure 8 are equal, but in radiofrequency ablation tip 9 each independently structure 8 the position of the same portion is not provided.

[0061] 如图6所示,当独立结构8为两个时,最好每个独立结构8上都设有ー个射频消融头9。 [0061] As shown in FIG 6, when an independent structure 8 is two, each individual structure preferably has 8 ー radio frequency ablation head 9. 如图6A所示,两个独立结构8的远端连接于消融段头端17,两个独立结构8最好等大,每个独立结构8长度优选为13—16mm,两个独立结构8的形变将使得两个独立结构8的中间部分相对隆起,形成类似纺锤形的结构,隆起最明显的地方一般位于独立结构8的中间或靠近中间的位置并将首先接触血管壁,此时射频消融头9最好设置于每个独立结构8隆起最明显的地方;每个独立结构8隆起最明显的地方可以不同(类似图19B所示);各独立结构8的中间隆起最明显的部分长度可以有所不同(类似图19D所示),此时射频消融头9在各独立结构8的设置位置可在同一横截面上或者不在同一横截面上。 6A, the distal end 8 is connected to two separate structures to the head end of the ablation segment 17, 8 is preferably two separate structures like large, the length of each individual structure 8 preferably 13-16mm, two separate structure 8 the deformation structure such that two separate intermediate portions of opposing ridges 8, spindle-like structure is formed, the bulge is generally located where the most significant independent intermediate structure 8 and a position at or near the middle of the first contact with the vessel wall, radiofrequency ablation head case 9 is preferably disposed on each individual ridge structure 8 where the most obvious; each independently ridge structure 8 may be different from the most significant place (similar to FIG. 19B); an intermediate structure 8 each independently raised most obvious part length may have except that (similar to FIG. 19D), radiofrequency ablation head 9 in this case the installation position 8 the same configuration independently of each cross section or may not in the same cross-section. 如图6B所示,两个独立结构8相互分离,两个独立结构8的长度最好相等,每个独立结构8长度优选为10—6mm,两个独立结构8的形变将使得两个独立结构8相互远离,一般独立结构8的头端及其附近位置相互远离最为明显并将首先接触血管壁,此时射频消融头9最好设置在各独立结构8的头端及其附近位置;若希望消融点在血管的不同横截面上,可使两个独立结构8的长度不相等(类似图21B所示),或者两个独立结构8的长度相等,但射频消融头9在各独立结构8头部的设置位置互不相同(类似图21C所示)。 6B, the two structures 8 independently from each other, the length of two independent structures 8 are preferably equal, the length of each individual structure 8 preferably 10-6mm, two separate structural deformation 8 will cause two separate structures 8 away from each other, generally independent of the structure of a position near the head end 8 and away from each other and the most significant first contact with the vessel wall, then radiofrequency ablation head 9 is preferably provided at a position near the head end and each independently structure 8; if desired different ablation points in the vessel cross section, the structure allows two independent unequal length 8 (similar to FIG. 21B), or two separate structural length equal to 8, but in radiofrequency ablation head 9 each independently structure 8 provided the position of the portion different from each other (similar to that shown in FIG. 21C). 如图6C所示,两个独立结构8的中间某处连接在一起远端再相互分离,两个独立结构8的长度优选相等,每个独立结构8的长度优选为6—26_,连接点18最好选择在独立结构8远端到连接点18的部分占整个独立结构8长度16—26%的地方;如图6C所示,两个独立结构8的形变将使得连接点18到独立结构8尾端的部分相对隆起,一般以该部分中间或靠近中间的位置相对隆起最明显,而连接点18到独立结构8头端的部分相互远离,一般以独立结构8的头端及其附近位置相互远离最为明显,此时将有四个位置优先接触血管壁,即两个独立结构8的头端及其附近位置和隆起最明显的地方,最好将射频消融头9设置于两个独立结构8的头端及其附近位置,而检测电极19可设置在中间隆起最明显的地方;若希望消融点在血管的不同横截面上,可使两个独立结构8中连接点18至独立结构8头端 Shown, somewhere in the middle of two separate structures 8 are connected together as shown in FIG 6C distal again separated from each other, two separate structural length preferably equal to 8, the length of each individual structure 8 is preferably 6-26_ connection point 18 preferably selected 8 point of attachment to the distal end of an independent structure portion 18 of the total length of 8 independent configuration where 16-26%; FIG. 6C, two separate structural deformation such that the connection point 8 of the structure 18 to a separate 8 part of the trailing end of the opposing ridges, generally in the middle of the section or a position near the middle of the opposing ridges most obvious point 18 to a separate structure 8 end portion connected to each other away from the general to the head end and its vicinity of the position independent structure 8 away from each other the most obviously, this case will have four priority position in contact with the vessel wall, i.e. two separate structure and the head end vicinity of the position where the most obvious and ridges 8, 9 is preferably a radio frequency ablation head 8 is provided in two separate head structure end position and the vicinity thereof, and detection electrodes 19 may be disposed in the middle of the raised most obvious place; if desired ablation at different points in the vessel cross section, an independent structure allows two connection points 8, 18 to a separate tip structure 8 间的部分长度不相等(类似图23B所示),或者两个独立结构8的长度相等,连接点18至独立结构8尾端之间的独立结构8的长度也相等,但射频消融头9在各独立结构8头部的设置位置不相同(类似图23C所示)O Unequal length between the portion (similar to FIG. 23B), or two separate structures 8 of equal length, the length of the connection between the individual structures 8 18 points to a separate tail structure 8 are equal, but in radiofrequency ablation head 9 8 each independently installation position of the head is not the same configuration (similar to FIG. 23C) O

[0062] 如图7所示,当独立结构8为三个时,最好每个独立结构8上都设有ー个射频消融电极头9。 [0062] As shown in FIG 7, when three independent structure 8, preferably 8 each independently have the structure of radio frequency ablation tip ー 9. 如图7A所示,三个独立结构8的远端连接于消融段头端17,三个独立结构8最好等大,每个独立结构8的长度优选为13—30mm,三个独立结构8的形变将使得三个独立结构8的中间部分四散隆起,形成类似纺锤形的结构,隆起最明显的地方一般位于独立结构8的中间或靠近中间的位置并将首先接触血管壁,各独立结构8的中间部分隆起最明显的地方最好有所不同,此时射频消融电极头9最好设置在隆起最明显的地方;或者各独立结构8的中间隆起最明显的部分长度有所不同,此时射频消融电极头9在各独立结构8上的设置位置最好不在同一横截面上。 7A, the distal end of three separate structure 8 is connected to the head end of the ablation segment 17, three independent structure like 8 is preferably large, the length of each individual structure 8 is preferably 13-30mm, three separate structures 8 the deformation structure such that three separate intermediate portion 8 of the scattered ridges, forming a structure similar to the spindle, where the most obvious general ridge in the middle or near the independent structure 8 and the first intermediate position in contact with the vessel wall, the structure 8 each independently the intermediate portion is preferably raised most obvious place is different, this time radiofrequency ablation tip bulge 9 is preferably disposed at the most obvious place; each independently structure of the intermediate or ridges 8 most significant part of the length is different, then 9 radiofrequency ablation electrode tip position is provided on each of the separate structure 8 is preferably not in the same cross-section. 如图7B所示,三个独立结构8相互分离,独立结构8的长度优选为10—20mm,三个独立结构8的形变将使得三个独立结构8相互远离,一般以独立结构8的头端及其附近位置相互远离最为明显,此时射频消融电极头9最好设置在各独立结构8的头端及其附近位置,三个独立结构8的长度可以不等,由于三个独立结构8的长度不同,因此各射频消融电极头9首先接触血管壁的位置也不在同一横截面上,如图9所示,射频消融电极头9接触肾动脉d的位置分别位于a、b、c三个不同的横截面上;或者三个独立结构8的长度相等,但射频消融电极头9在各独立结构8头部的设置位置互不相同。 7B, three separate structures 8 are separated, the length of an independent structure 8 is preferably 10-20mm, three separate structural deformation will be such that three separate 8 8 structure away from each other, generally the head end of the separate structure 8 its most obvious near a position apart from each other, radiofrequency ablation case 9 is preferably provided at the tip end of the head 8 each independently of the structure and its position near the length of three separate structure 8 may vary, since three separate structure 8 different lengths, and therefore the position of the radio frequency ablation tip first contacts the vessel wall 9 is not in the same cross-section, shown in Figure 9, radiofrequency ablation electrode contacts the head position of the renal artery d 9 are located a, b, c in three different three separate equal length or structure 8, but radiofrequency ablation tip 9 is provided in a position different from each other are each independently of the structure of the head 8; cross section. 三个独立结构8的中间某处连接在一起远端再相互分离,连接点18最好选择在最长的独立结构8远端到连接点18的部分占整个最长的独立结构8长度30—50%的地方,优选地,每个独立结构8长度为20-40mm ;如图7C所示,为了使得消融点不在血管的同一横截面上,三个独立结构8的长度可不等,但连接点18至独立结构8尾端之间的部分长度最好是相等的,三个独立结构8的形变将使得三个独立结构8上连接点18到独立结构8尾端的部分四散隆起,一般以该部分中间或靠近中间的位置相对隆起最明显,而连接点18到独立结构8头端的部分相互远离,一般以独立结构8的头端及其附近位置相互远离最为明显,此时将有六个位置优先接触血管壁,即三个独立结构8的头端及其附近位置和隆起最明显的地方,此时射频消融电极头9最好设置在独立结构8的头端及其附近位置;或者三个独 Three separate structure joined together somewhere in the middle of the distal end 8 and then separated from each other, the connection point 18 to the point of attachment is preferably selected portion 18 of the total longest independent structure standing structure 8 8 the distal end of the longest length of 30- where 50%, preferably, each is independently of length 20-40mm structure 8; FIG. 7C, for the same cross-section such that the ablation site is not a blood vessel, the length of three separate structures 8 may not like, but the connection points the best part of the length between the trailing end 18 to a separate structure is equal to 8, 8 three independent structural deformation will be such that three separate moiety point 18 to a separate structure connected to the trailing end 8 8 scattered ridges, generally in the portion near the middle or intermediate position relative to the most significant ridges, independently of the structure 18 to the point 8 connected to an end portion away from one another, and generally a position near the head end 8 of the individual structures away from each other most apparent at this time will have six priority position contact with the vessel wall, i.e., the structure of three separate head end and its vicinity of the position where the most obvious ridges 8, radiofrequency ablation tip 9 at this time is preferably disposed at a position near the head end and the independent structure 8; or three independent 立结构8的长度相等,连接点18至独立结构8尾端之间的部分长度也相等,此时射频消融电极头9在各独立结构8头部的设置位置互不相同;如图7C所示,连接点18至独立结构8尾端之间隆起最明显的地方可设置电极19。 Stand structure 8 equal length, the length of the connecting portion between the points 18 to the trailing end of an independent structure also equal to 8, radiofrequency ablation tip 9 at this time differ from each other in the installation position of each of the individual structures of the head 8; FIG. 7C connection point 18 between the ridges to a separate structure 8 where the trailing end of the most obvious electrode 19 may be provided.

[0063] 如图8所示,当独立结构8为四个时,最好每个独立结构8上都设置一个射频消融电极头9。 [0063] As shown in FIG. 8, when an independent structure 8 is four, each is independently preferably 8 are disposed on a structure radiofrequency ablation tip 9. 如图8A所示,四个独立结构8的远端连接于消融段头端17,四个独立结构8最好等大,每个独立结构8的长度优选为13—30mm,四个独立结构8的形变将使得四个独立结构8的中间部分四散隆起,形成类似纺锤形的结构,隆起最明显的地方一般位于独立结构8的中间或靠近中间的位置并将首先接触血管壁,各独立结构8的中间部分隆起最明显的地方最好有所不同,此时射频消融电极头9最好设置在隆起最明显的地方;或者各独立结构8的中间隆起最明显的部分长度有所不同,此时射频消融电极头9在各独立结构8上的设置位置最好不在同一横截面上。 8A, the distal end of the four independent structure 8 is connected to the head end of the ablation segment 17, preferably four independent 8 and other large structures, the length of each individual structure 8 is preferably 13-30mm, four independent structures 8 the four independent deformation such that the intermediate portion 8 of the structure scattered ridges are formed similar to the structure of the spindle, where the most obvious ridges generally independent structure in the middle or near the middle of the 8 position and first contacts the vessel wall structure 8 each independently the intermediate portion is preferably raised most obvious place is different, this time radiofrequency ablation tip bulge 9 is preferably disposed at the most obvious place; each independently structure of the intermediate or ridges 8 most significant part of the length is different, then 9 radiofrequency ablation electrode tip position is provided on each of the separate structure 8 is preferably not in the same cross-section. 如图8B所示,四个独立结构8相互分离,独立结构8的长度优选为10—20mm,四个独立结构8的形变将使得四个独立结构8相互远离,一般以独立结构8的头端及其附近位置相互远离最为明显,四个独立结构8的长度可以不等,此时射频消融电极头9优选设置在独立结构8的头端及其附近位置,由于四个独立结构8的长度不同,因此各射频消融电极头9首先接触血管壁的位置也不在同一横截面上;或者四个独立结构8的长度相等,但射频消融电极头9在各独立结构8头部的设置位置互不相同。 8B, the four independent structures 8 are separated, the length of an independent structure 8 is preferably 10-20mm, four independent structural deformation will be such that four independent 8 8 structure away from each other, generally the head end of the separate structure 8 its most obvious near a position apart from each other, the length of four independent structures 8 may vary, radiofrequency ablation tip 9 at this time is preferably provided at a position near the head end and the independent structure 8, since the length of four different independent structure 8 , the position of the radio frequency ablation tip first contacts the vessel wall 9 is not in the same cross section; structure or four independent 8 of equal length, but radiofrequency ablation tip 9 is provided at a position of the head 8 are each independently of the configuration different from each other . 如图SC所示,四个独立结构8的中间某处连接在一起远端再相互分离,连接点18最好选择在最长的独立结构8远端到连接点18的部分占整个最长的独立结构8长度30—50%的地方,优选地,每个独立结构8长度为20-40mm ;如图SC所示,为了使得消融点不在血管的同一横截面上,四个独立结构8的长度可不等,但连接点18至独立结构8尾端之间的部分长度最好是相等的,四个独立结构8的形变将使得四个独立结构8上连接点18到独立结构8尾端的部分四散隆起,一般以该部分中间或靠近中间的位置相对隆起最明显,而连接点18到独立结构8头端的部分相互远离,一般以独立结构8的头端及其附近位置相互远离最为明显,此时将有八个位置优先接触血管壁,即四个独立结构8的头端及其附近位置和隆起最明显的地方,此时射频消融电极头9设置在独立结构8的头端及其附近位置;或 As illustrated, four separate intermediate structure 8 SC connected together somewhere in the distal end and then separated from each other, the connection point 8 the distal end 18 is preferably selected in an independent structure to the longest point of the connecting portion 18 of the total longest 8 independent structure where the length of 30-50%, preferably, each is independently of length 20-40mm structure 8; shown in FIG. SC, such that the ablation points to the same cross-section is not a blood vessel, the structural length of four independent 8 may not like, but the best part of the length between the connection point 18 to the trailing end of structure 8 is independently equal, four independent structural deformation will be such that four independent 8 moiety point 18 to a separate structure connected to the trailing end 8 8 scattered ridges, generally near the middle of the intermediate portion or the relative position of the most significant ridges, independently of the structure 18 to the point 8 connected to an end portion away from one another, and generally a position near the head end 8 of the individual structures away from each other most apparent at this time priority position would have eight contact with the vessel wall, i.e. four independent structures and near the head end and the position where the most obvious ridges 8, 9 at this time radiofrequency ablation tip structure disposed in a separate head end and its vicinity of the position 8; or 四个独立结构8的长度相等,连接点18至独立结构8尾端之间的部分长度也相等,此时射频消融电极头9在各独立结构8头部的设置位置互不相同;如图SC所示,连接点18至独立结构8尾端之间隆起最明显的地方可设置电极19。 Four independent structural length is equal to 8, the length of the connecting portion between the points 18 to the trailing end of an independent structure also equal to 8, radiofrequency ablation tip 9 at this time differ from each other in the installation position of each of the individual structures of the head 8; FIG SC , the connection points between the ridges 18 to separate the trailing end of the structure 8 may be the most obvious place the electrode 19. 如图8D所示,四个独立结构8中有两个相対的独立结构8相互分离,而另外两个相対的独立结构8的远端连接于消融段头端17,优选地,每个独立结构8的长度为13—30mm ;如图8D所示,对于远端连接于消融段头端17的两个独立结构·8最好等大,这两个独立结构8的形变将使得它们的中间部分相对隆起,隆起最明显的地方一般位于这两个独立结构8的中间或靠近中间的位置并将首先接触血管壁,这两个独立结构8的中间部分隆起最明显的地方最好有所不同,射频消融电极头9优选设置在隆起最明显的地方,或者这两个独立结构8的中间隆起最明显的部分长度有所不同,此时射频消融电极头9在这两个独立结构8上的设置位置最好不在同一横截面上;如图8D所示,对于相互分离的两个独立结构8长度可不同,这两个独立结构8的形变将使得它们相互远离,一般以这两个独立结 8D, there are four independent 8 two structurally independent structure Dui phase 8 separated from each other, independently of the structure and the distal end of the other two phases Dui 8 is connected to the head end of the ablation segment 17, preferably, each independently structure 8 is a length 13-30mm; 8D, the distal ablation segment is connected to two separate head end and other large structures is preferably 2.8 17, 8 two separate structural deformation will be such that an intermediate portion thereof opposing ridges, ridge where the most obvious is generally located intermediate the two separate structures 8 or a position near the center and the first contact with the vessel wall, the two separate structure of the intermediate portion 8 is raised most obvious place preferably different, radiofrequency ablation electrode head 9 is preferably provided at the raised most obvious place, or two separate intermediate structure 8 is raised most significant part of the length is different, this time radiofrequency ablation tip 9 is provided on two separate structure 8 preferably not in the same position of the cross-section; shown, separated from each other for the two independent structures 8 may be different lengths as shown in FIG 8D, the two separate structural deformation 8 away from each other such that they will, generally two separate junctions 构8的头端及其附近位置相互远离最为明显,射频消融电极头9优选设置在这两个独立结构8的头端及其附近位置,或者这两个独立结构8的长度相等,而射频消融电极头9在这两个独立结构8头部的设置位置有所不同;上述设计最终将使得四个射频消融电极头9接触血管壁的位置在互不相同的横截面上。 8 and the configuration of the head end vicinity of the position away from each other the most obvious, and radiofrequency ablation at a position near the head end of the two separate structure 8, two separate structures or equal to the length of the electrode 8 head 9 is preferably provided, and radiofrequency ablation tip 9 different in the installation position of the two independent head structure 8; such that the final position of the above-described design of the four RF ablation electrode head 9 in contact with the vessel wall at mutually different cross-section. 如图SE所示,四个不等长的独立结构8的远端连接于牵引丝10的不同部位,优选地,独立结构8的长度为13—30mm,牵引丝10与消融导管I的长轴中心线重合;当四个独立结构8在牵引丝10的作用下发生形变时,各独立结构8的中间部分将四散隆起,隆起最明显的地方将首先接触血管壁,由于独立结构8不等长且在牵引丝上的固定位置不同,因此隆起最明显的地方也会不同,这样将射频消融电极头9设置在这些隆起最明显的地方就保证了消融点不在肾动脉的同一横截面上。 FIG SE, four unequal independent distal end connected to the structure of 8 different parts of the pull wire 10 is, preferably, independent of the length of the structure 8 is 13-30mm, the pull wire 10 with the major axis of the ablation catheter I line coinciding; four independent structure 8 when deformed under the action of the traction wire 10, each independently of the structure of the intermediate portion 8 will be scattered bump, bump most obvious place will first contact the vessel wall, due to the unequal-length independent structure 8 different fixed positions and on the dragline silk, and therefore raised the most obvious place will be different, so that the radiofrequency ablation tip 9 is provided in these ridges most obvious place to ensure that the point is not in the same cross-section of the renal artery ablation. 此外消融段6的横截面外轮廓最好与可控弯曲段5的横截面外轮廓相似,各独立结构8在消融段6的外轮廓范围内尽量紧凑的排布,如图10所示,当独立结构8为两至四个时,每个独立结构8最好在横截面上平分圆形。 Further ablation segment cross-sectional outer contour 6 is preferably similar to the contour of curved cross-section controllable outer sections 5, each independently structure 8 within the outer contour of the ablation range section 6 of the arrangement as compact as possible, as shown in FIG. 10, when 8 is an independent structure two to four, each is independently preferably 8 bisecting a circular configuration in cross section. 当然随着独立结构8数量的増加,独立结构8的横截面轮廓也可以采用其他设计使得各独立结构8的在消融段6的外轮廓范围内尽量紧凑的排布。 Of course, as an independent structure to increase in number of 8, the cross-sectional profile of the individual structures 8 may be designed differently so that each individual structures within the scope of the ablation section of the outer contour 6 of the arrangement as compact as possible 8. 对于独立结构8数量继续增加的情況,优选地采用如下设计方案,即各独立结构8的远端可连接于消融段头端17、各独立结构8相互分离和不等长的独立结构8的远端连接于牵引丝10的不同部位,这些设计方案可仿照独立结构8为三个和四个时对应的设计方案。 In the case of 8 continue to increase the number of independent structure, preferably using the following design scheme, i.e., the distal end of structure 8 may be each independently connected to the head end of the ablation segment 17, the structure 8 each independently from each other and independent of the structure far unequal 8 end is connected to different parts of the traction wire 10, these structural designs may be modeled independently 8 to design three and four corresponding time.

[0064] 设置可控弯曲段5的主要作用是有助于消融段6更方便的到达指定的消融位置,例如使得消融段6更容易通过血管的弯曲、使得消融段6更容易向指定方向偏转等。 [0064] provided with a controllable bending section 5 primary role is to contribute to the ablation section 6 more easily reaches the specified position of the ablation, for example, such that the ablation section 6 more easily through tortuous vessels, so that the ablation section 6 more easily deflected in a predetermined direction Wait. 可控弯曲段5优选采用圆柱形或类圆柱形设计,根据不同的设计方案可控弯曲段5的长度有所不同。 A controlled deflection section 5 is preferably used cylindrical or almost cylindrical design, the curved length 5 of the controllable vary depending on design. 图11显示了可控弯曲段5为“C”形弯曲设计时工作状态下的情況,图25是以消融段6的独立结构8为两个时进行说明的,对于消融段6为其他设计形式时,只需要替换消融段6即可。 Figure 11 shows the case where the operating state of the controlled deflection section 5 is "C" shaped bend design, FIG. 25 is a structure independent of the ablation section 6 will be described as two 8 when the ablation section 6 for other design forms when only need to replace the ablation segment 6. 如图11所示,可控弯曲段5形变后的形状为“C”形,实线部分的可控弯曲段5表示了ー种“C”形弯曲的情况,在这种形状下,可控弯曲段5优选长度为60—120_,可控弯曲段5将有两个地方Cl和c2与血管内侧壁接触,其中Cl与肾动脉a的内侧壁接触,而c2与腹主动脉b的内侧壁接触,这样有利于在消融时稳定射频消融电极头9,可控弯曲段5此时最好与其中的ー个独立结构8在同一平面上,这样对于独立结构8上仅有射频消融电极头9作为电脉冲发放或/和接收电极的情况,可在Cl设置电极19,这样射频消融电极头9或独立结构8上的电极19与可控弯曲段5上的电极19将形成一个发放电脉冲、一个接收电脉冲,当然为适应不同管径的肾动脉,可以在Cl附近设置多个环状接收电极19 ;如图11所示,虚线部分的可控弯曲段5表示了另一种” C”形弯曲的情况,在这种情况下,可控弯曲段 11, the controlled deflection shape after deformation section 5 of "C" shape, the curved section 5 controllable solid line indicates the case where the kinds ー "C" shaped bend, in such a shape, controllable preferably curved section length 60-120_ 5, controlled deflection section 5 Cl and c2 two places in contact with a blood vessel sidewall, wherein the sidewalls of the contact Cl of a renal artery, and the inner side walls b of the abdominal aorta and c2 contacting, it is a good stability radiofrequency ablation during an ablation tip 9, the curved section 5 at this time is preferably controlled with separate structures ー 8 on the same plane, so that an independent structure for radiofrequency ablation tip 8 wherein only 9 as the issuing electrical pulses or / and receiving electrode, the electrode 19 may be Cl, so that the electrodes on the electrode head 9 or 8 independent radiofrequency ablation structure 19 and the controllable electrodes on curved sections 519 will form an electrical pulse distribution, receiving an electrical pulse, of course, to adapt to different diameters of the renal artery, may be provided a plurality of annular electrodes 19 in the vicinity of the receiving Cl; 11, a broken line part a controlled deflection section 5 shows another "C" the case-shaped bend, in this case, controlled deflection section 5优选长度为40-100mm,可控弯曲段5可以不与动脉的内侧壁接触,或者仅有一个地方c2与动脉的内侧壁接触,这样射频消融电极头9的稳定将主要依靠各独立结构8与动脉的内侧壁接触形成的支撑点。 5 is preferably a length of 40-100mm, controlled deflection section 5 may not contact with the inner side wall of the artery, or only a place in contact with the inner sidewall c2 artery, so that stable radiofrequency ablation tip 9 will mainly depend on the structure 8 each independently contacting the support point formed by the inner side wall of the artery.

[0065] 根据具体情况,技术人员可以对上述这些消融段6和可控弯曲段5的设计方案进行融合、改进及交叉使用,这些等效变化和修饰同样落入本发明的实施例权利要求所限定的范围。 [0065] Depending on circumstances, the art can be fused to the above-described design of ablation segments 6 and 5, controlled deflection section, and improving cross-use, such equivalent variations and modifications are also within the present embodiment of the invention as claimed in claim defined range.

[0066] 所述的可控弯曲段5、独立结构8和导引导管7可以有预制形变,例如如图11所示,在体外制造时可以事先将可控弯曲段5预置成“C”形弯曲,使得消融段6可以顺利进入肾动脉。 [0066] The controllable bending section 5, an independent structure 8 and 7 may be prefabricated guide catheter deformed, for example, as shown previously in vitro can be controllably manufactured curved section preset to 5 "C" 11 shaped bend, such that the ablation section 6 can smoothly enter the renal artery. 技术人员可以通过在可控弯曲段5、独立结构8和导引导管7中加入具有形状记忆功能的材料来实现在体外对预制形变进行调整,例如:在可控弯曲段5中加入形状记忆合金,可以先将其在体外的弯曲形态预先制成“C”形弯曲,当需要可控弯曲段5改变弯曲形态时,又可以再次将其拿出体外通过温度变化将可控弯曲段5制成其他形状的弯曲样式。 Can be controlled by the skilled person bent section 5, a shape memory material having a separate structure added in conduit 8 and the guide 7 is achieved adjust the preform deformation in vitro, for example: a shape memory alloy is added in a controlled curved section 5 , which may be preformed first "C" shaped in a curved shape bending in vitro, when it is desired to change the controllable curved shape curved section 5, but it may be out again in vitro by a temperature change curved section 5 is made controllable other styles of curved shapes.

[0067] 所述的导引导管7的主要作用是套在消融导管I外起到引导消融导管I方向、容纳消融导管I和为消融导管I提供通道,因此导引导管7的内径因较消融导管I外径略大,此外导引导管7有时还可以起到为消融导管I的形变提供支点的作用。 [0067] The main role of the guide catheter sheath 7 is to act as a guide catheter ablation I direction, to accommodate the ablation catheter and ablation catheter I I I provide an ablation catheter in the outer channel, and therefore the inner diameter of the guide catheter ablation than 7 due to slightly larger than the outer diameter of the catheter I, furthermore the guide catheter 7 can sometimes functions to provide a fulcrum for the deformation effect I ablation catheter. 图12、图13、图14、图15是以两条独立结构8为例,显示了导引导管7能够为消融导管I的形变提供支点的情况下,导引导管7头部的主要结构特点;其中图12显示的是独立结构8相互分离时导引导管7头部的主要结构特点,图13显示的是独立结构8相互分离时导引导管7及独立结构8工作状态下的情况,图14显示的是独立结构8的远端连接于消融段头端17时导引导管7头部的主要结构特点,图15显示的是独立结构8中间某处连接在一起远端再相互分离时导引导管7头部的主要结构特点。 FIG 12, FIG 13, FIG 14, FIG 15 is an example two separate structures 8, shows the case where the guide catheter 7 to provide a fulcrum for the deformation of the ablation catheter I, the main structural features of the guide catheter head 7 ; Figure 12 shows the main structural features of the guide catheter head 7 separated from each other when an independent structure 8, FIG. 13 shows the case where the guide pipe 7 and the operation state when an independent structure 8 structure 8 independently from each other, FIG. 14 shows the structure of the distal end 8 is connected to the separate main structural characteristics of the ablation segment head end 17 of head 7 when the guide catheter, FIG. 15 shows the structure of 8 independent connection somewhere in the middle and then separated from each other with the distal end of the guide the main structural features of the guide tube 7 of the head. 图16是以远端连接于消融段头端17的两条独立结构8为例,显示了导引导管7不为消融导管I的形变提供支点的情况下,导引导管7头部的主要结构特点。 FIG 16 is connected to the distal end of the ablation head section 8 of the two individual structures 17 as an example, the case where the main structural guide catheter 7 is not deformed to provide a fulcrum for the ablation catheter I and guiding catheter head 7 features.

[0068] 对于导引导管7能够为消融导管I的形变提供支点的情况,导引导管7的头部优选设置与血管相通的斜孔74或/和侧槽76。 [0068] In the case of a guide catheter 7 to provide a fulcrum for the deformation of the ablation catheter I, preferably the guide head is provided with a conduit inclined hole 7 communicating vessels 74 and / or side grooves 76. 斜孔74和侧槽76主要作为独立结构8向导引导管7外伸出的通道,实现独立结构8与血管壁接触,当然斜孔74和侧槽76也可以作为向血管内注药或/和注射造影剂的通道。 Helical groove 76 and the side holes 74 as the main channel 7 extends outside the guide tube guide 8 independent structure, independence structure 8 in contact with the vessel wall, of course, the slant holes 74 and the side grooves 76 may be used as injection into the blood vessels or / and contrast agent injection channel. 根据独立结构8数量和两两独立结构8相互连接方式的不同导引导管7头部的斜孔74和侧槽76的设置方式也不同。 The oblique arrangement of interconnected holes of different guide catheter embodiment of an independent structure 8 and the number of pairwise independent head structure 87 and the side 74 of the groove 76 is also different. 图12A、图12B、图12C为纵剖面示意图,图12D、图12E为透视示意图。 FIGS. 12A, 12B, 12C is a schematic longitudinal section, FIG. 12D, FIG. 12E is a perspective view of FIG. 如图12所示,当独立结构8相互分离时,在导引导管7的头端(远端)或头部侧壁上开出若干与各独立结构8相对应的斜孔74 ;如图12A、12D所示,斜孔74可开于导引导管7的头端,如图12B、图12C所示,斜孔74也可开于导引导管7的头部侧壁上,每个斜孔74的内径大于独立结构8的外径,一般I. 4—2. 4mm,每个斜孔74的倾斜角度一般为16-50度,同时斜孔74的数量优选等于独立结构8的数量,斜孔74间的连接部分75优选呈锥状,连接部分75不仅能够限制可控弯曲段5被前推出导引导管7还有助于引导独立结构8从斜孔74处被前推出。 12, when the structure 8 independently from each other, out of a plurality of slant holes and 8 each independently corresponding structure on the head end of the guide catheter. 7 (distal end) of the head or the side wall 74; FIG. 12A as shown, each of the slant holes 74 may be inclined hole opened at the head end 7 of the guide catheter, FIG. 12B, FIG. 12C, the slant holes 74 may be opened on the side wall guide catheter head 7, 12D an inner diameter larger than an outer diameter of 74 8 independent structure, generally I. 4-2. 4mm, the inclination angle of each inclined hole 74 is generally 16-50 degrees, while the number of the oblique hole 74 is preferably equal to the number of independent structure 8, the swash between the connecting portion 75 is preferably tapered bore 74, the connecting portion 75 can be restricted only controlled deflection section 5 is pushed guide catheter before the guide 7 also helps separate structure 8 Release from the oblique bore 74 by the front. 若推送消融导管I或回退导引导管7,如图12C、图13所示,独立结构8将从斜孔74内向外呈辐散状被推入血管,独立结构8头部的射频消融电极头9将优先与血管壁接触;通过控制推送消融导管I或回退导引导管7的距离以及斜孔74的傾斜度,即可控制独立结构8远端相互分离的距离及射频消融电极头9与血管壁接触的压力。 If I push the ablation catheter or guide catheter backoff 7, FIG. 12C, as shown, was pushed into the spokes bulk vessels, independent RF ablation electrode structure 8 of the head 8 from the outwardly inclined hole 13 independent structure 74 of FIG. the head 9 in contact with the vessel wall priority; push the ablation catheter via the control I or backoff from the guide duct 7, and the inclination of the inclined hole 74, the distal end of structure 8 can be controlled independently from each other a distance and radiofrequency ablation electrode head 9 the pressure contact with the vessel wall. 对于独立结构8的远端汇集于消融段头端17的情況,图14A、图14B为纵剖面示意图,图14C为透视图。 8 independent structure to the distal end of the ablation segment is collected in the head end of the case 17, 14A, FIG. 14B is a schematic longitudinal section, FIG. 14C is a perspective view of FIG. 如图14A、图14C所示,当独立结构8的远端汇集于消融段头端17吋,导引导管7的头端开ロ优选通过结构设计的方式限制消融段头端17被前推出导引导管7,优选可设置缩ロ结构73使导引导管7头端开ロ的孔径小于消融段头端17的外径(图14A所示),抑或用堵头72封闭导引导管7的头端开ロ(图14B、图14C所示);如图14所示,导引导管7的头端侧壁上优选地设置有与独立结构8的长度相近且与血管相通的侧槽76,侧槽76的长度一般为12—14mm,该侧槽76优选与独立结构8平行对应,侧槽76的宽度略大于独立结构8的外径,一般为I. 4—2. 4mm,并且侧槽76的数量优选等于独立结构8的数量。 FIG. 14A, as shown, when the distal end of the collection structure 8 independent segments in the ablation head end 17 inches, the guide catheter tip 7 is preferably open ro by way of limitation of the structural design of the ablation segment head front end guide 17 is pushed FIG. 14C the guide tube 7, preferably provided that the header compression ro configuration guide catheter 73 open end 7 ro aperture smaller than that of the head end 17 of the ablation section (FIG. 14A), or the guiding catheter 72 is closed by plug 7 ro open end (14B, a shown in FIG. 14C); As shown, the guide catheter preferably is provided on a sidewall of the head end 147 are similar to the length of the individual structures 8 and communicating with the vessel side groove 76, the side length of the slot 76 is typically 12-14 mm, and the side groove 76 is preferably an independent structure 8 parallels, the width of the groove 76 is slightly larger than the outer diameter of the side structure 8 independent, typically I. 4-2. 4mm, and the side groove 76 number preferably equal to the number of independent structure 8. 若推送消融导管I或回退导引导管7,如图14B所示,消融段头端17因为堵头72的限制将使得独立结构8从相应的侧槽76处隆起膨出,将使得射频消融电极头9优先与血管壁相接触;通过控制推送消融导管I或回退导引导管7的距离,即可控制独立结构8中间部分相对隆起的间隔距离及射频消融电极头9与血管壁接触的压力。 If I push the ablation catheter or a guide catheter 7 backoff, 14B, the head end of the ablation segment 17 because of the restrictions such that the plug 72 will separate from bulging ridge structure 8 at the respective side of the groove 76, such that the RFA 9 priority tip in contact with the vessel wall; push the ablation catheter via the control I or backoff from the guide conduit 7, 8 can be controlled independently of the structure of the intermediate portion raised relative distance and radiofrequency ablation tip in contact with the vessel wall 9 pressure. 对于独立结构8的中间某处连接在一起远端再相互分离的情況,导引导管7头部的设计方案结合了图12、图13、图14所示意的设计方案。 Somewhere in the case of the intermediate structure 8 are joined together independently of the distal end and then separated from each other, the guide catheter design combines the head 7 in FIG. 12, FIG 13, FIG 14 a schematic design. 如图15A所示,在导引导管7的头部侧壁上设置若干与血管相通小的斜孔74或者在导引导管7的头端设置若干小的斜孔74(类似图12A、图12D所示),然后在斜孔74之后一定距离的导引导管7的侧壁上再设置与斜孔74相对应且与独立结构8相平行的侧槽76,斜孔74与侧槽76的间隔距离一般为2. 5—5. 5mm,每个斜孔的内径略大于独立结构8的外径,一般为I. 4—2. 4mm,每个斜孔74的倾斜角度一般为16—50度,斜孔间的连接部分75优选呈锥状,连接部分75不仅能够限制连接点18和可控弯曲段5被前推出导引导管7还有助于引导独立结构8从斜孔74处被前推出,侧槽76的宽度优选略大于独立结构8的外径,一般为I. 4—2. 4mm,侧槽76的长度与独立结构8近端到连接点18的部分的长度相近,一般为10—22_,斜孔74和侧槽76的数量优选等于独立结构8的数量。 15A, is provided with a plurality of small slant holes communicating vessels in the head 7 of the side wall 74 or guide catheter provided with a plurality of small slant holes 74 (FIG. 12A is similar to the head end 7 of the guide catheter, FIG. 12D shown), and then again after the oblique bore 74 is provided with spaced holes 74 oblique to the side and corresponding grooves 8 parallel independent structures 76, 74 with the inclined hole 76 on the side groove side wall of the guide catheter at a distance of 7 distance is generally 2. 5-5. 5mm, slightly larger than the inner diameter of each hole is inclined outer diameter of 8 independent structure, typically I. 4-2. 4mm, the inclination angle of each inclined hole 74 is generally 16-50 degrees the connection between the inclined hole portion 75 is preferably tapered, connecting portion 75 is not only capable of limiting the connection point 18 and the controlled bending section 5 is pushed guide catheter before the guide 7 also helps to separate the structure 8 from the front 74 is inclined hole Release, side groove width slightly larger than the outer diameter 76 is preferably separate structure 8, usually I.. 4mm 4-2, the length of the side grooves 76 with an independent structure to the connection point 8 of the proximal end portion 18 of similar length, typically 10-22_ number of slant holes 74 and the side groove 76 is preferably equal to the number of independent structure 8. 若推送消融导管I或回退导引导管7,如图15B所示,独立结构8远端到连接点18之间的部分将从斜孔74内向外呈辐散状被推入血管,独立结构8头部的射频消融电极头9将优先与血管壁接触,独立结构8近端到连接点18之间的部分将从对应的侧槽76处隆起膨出,隆起最明显的地方将优先与血管壁接触;通过控制推送消融导管I或回退导引导管7的距离以及斜孔74的傾斜度能够控制独立结构8远端相互分离的距离及射频消融电极头9与血管壁接触的压力。 If the push portion of the ablation catheter or I backoff guide catheter 7, as shown in FIG, 8 independent structure to the distal end 15B is connected between the point 18 from the outwardly inclined as a spoke hole 74 is pushed into the bulk vessel, an independent structure RF ablation tip 8 of the head 9 will preferentially contact with the vessel wall, freestanding structure 8 to the connection point between the proximal end portion 18 from a corresponding side of the groove 76 bulging ridges, the ridges most obvious place preferentially vessel contacting wall; push the ablation catheter via the control I or backoff from the guide catheter and the inclination of the swash 7 hole 74 can be controlled independently from each other in structure from the distal end 8 and radiofrequency ablation tip 9 pressure contact with the vessel wall. 对于部分相対的独立结构8相互分离而部分相対的独立结构8的远端连接于消融段头端17的情况,也可以借鉴图12、图13、图14、图15所示意的导引导管7头部设计方案的思路,在导引导管7的头部优选同时设置斜孔74和侧槽76 ;斜孔74与远端连接于消融段头端17的独立结构8相对应并优选设置在导引导管7头部的侧壁上,但也可以设置在导引导管7头端的开ロ处,侧槽76与相互分离的独立结构8对应并优选设置在距斜孔74 一定距离的导引导管7的侧壁上,侧槽76与斜孔74不在同一直线上且分别与相应的独立结构8对应,以四条独立结构8为例,两个斜孔74在导引导管7头部的上下两个侧壁上,而两个侧槽76则在导引导管7头部的左右两个侧壁上;每个斜孔74的大小能让独立结构8通过,一般为I. 4-2. 4mm,同时斜孔74的数量优选等于相互分离的独立结构8的数量,斜孔74间的连接部 Guide catheter for separate moieties Dui phase 8 separated from each other while the distal end of an independent structure Dui phase 8 moiety is attached to the case 17 of the ablation segment head end can learn FIG 12, FIG 13, FIG 14, FIG 15 schematically 7 thinking of the head design, the guiding catheter head 7 is preferably provided while the inclined hole 74 and the side groove 76; inclined hole 74 and is connected to the distal end of the ablation head section 8 of the individual structures 17 and is preferably disposed corresponding to the guide the guide tube on the side wall 7 of the head, but may be provided at the opening of the guide catheter ro end 7, the side groove 76 and separated from each other and corresponding to a separate structure 8 is preferably disposed at a distance from the guide catheter 74 from the inclined hole on the side wall 7, a side groove 76 and the slant holes 74 are not aligned and respectively with the respective independent structure 8, to four independent structure 8 as an example, two upper and lower oblique bore 74 in the head portion of the guide catheter 7 on a side wall and two side grooves 76 on both left and right sidewalls of the guide catheter head 7; the size of each hole 74 allows the swash 8 by an independent structure, typically I. 4-2 4mm. , while the number of slant holes 74 is preferably separated from one another equal to the number of individual structures 8, the connecting portion between the slant holes 74 75优选呈锥状,连接部分75不仅能够限制消融段头端17和可控弯曲段5被前推出导引导管7还有助于引导相互分离的独立结构8从斜孔74处被前推出,侧槽76的宽度大于独立结构8的最大横径,一般为I. 4—2. 4mm,侧槽76与远端汇集于消融段头端17的独立结构8的长度相近,一般为12—14_,侧槽76的数量优选等于远端汇集于消融段头端17的独立结构8的数量;若推送消融导管I或回退导引导管7,对于相互分离的独立结构8,它们将从斜孔74内向外呈辐散状被推入血管,独立结构8头部的射频消融电极头9将优先与血管壁接触,对于连接于消融段头端17的独立结构8,由于消融段头端17被斜孔74 间的连接部分的限制将使得这些独立结构8从相应的侧槽76处隆起膨出,并使得射频消融电极头9优先与血管壁相接触。 75 is preferably tapered, connecting portion 75 is not only capable of restricting the ablation section 17 and the head end section 5 is controlled deflection guide catheter prior to Release 7 further help to guide individual structures 74 separated from each other by the front Release 8 from the oblique holes, the width of the side groove 76 is greater than the maximum diameter of 8 independent, typically I. 4-2. 4mm, side grooves 76 and the distal ablation segment is collected in separate structures 17 close to head end 8 of length, typically 12-14_ , the number of lateral groove 76 is preferably equal to the number of separate collection of the distal end structure 17 of the head end 8 of the ablation section; if I push the ablation catheter or guide catheter backoff 7, separated from each other for independent structure 8, are inclined hole from 74 was pushed outward radial bulk vessels, the head 8 separate RF ablation tip structure 9 will preferentially contact with the vessel wall, for connection to the ablation section 17 of the head end 8 independent structure, since the head end of the ablation section 17 is limiting the connecting portion between the inclined hole 74 such that these separate structures 8 bulging ridges 76 from the respective side of the groove, and radiofrequency ablation tip 9 so that the priority is in contact with the vessel wall. 上述设计方案中的斜孔74和侧槽76也具有向血管内注药或注射造影剂的作用。 The above-described design of the slant holes 74 and the side grooves also have a 76 to intravascular injection or injection of contrast agent. 为了方便独立结构8形成设计形变,可以通过调整独立结构8的结构设计或通过改变制造材料硬度使设计形变更容易实现。 8 is formed in order to facilitate an independent structure design deformation, or may be designed so that by varying the hardness of the material for producing shaped design easily changed by adjusting the individual structures of the structure 8. 图12、图13、图14、图15是以两条独立结构8为例进行设计方案说明的,因此不局限于两条条独立结构8的情况,对于多于两条独立结构8的情况只需要按照图12、图13、图14、图15所示意的设计思路调整斜孔74与侧槽76的数量和设置位置。 FIG 12, FIG 13, FIG 14, FIG 15 is an example for two independent design structure 8 described and is therefore not limited to the two strips is independently structure 8, in the case of more than two separate structure 8 only need in FIG. 12, FIG 13, FIG 14, FIG 15 is a schematic oblique design ideas to adjust the number and location of the apertures 74 is provided with the groove 76 side.

[0069] 对于导引导管7不能够为消融导管I的形变提供支点的情况,独立结构8优选设置预制形变,可控弯曲段5可以设置预制形变,然后将消融导管I压入导引导管7内,当导引导管7的头端到达指定位置后,消融导管I可从导引导管7头端的开口被推送出来,恢复预制形变。 [0069] In the case of a guide catheter 7 can not provide a fulcrum for the deformation of the ablation catheter I, an independent structure 8 is preferably provided pre-deformation, controlled deflection section 5 may be provided pre-deformation, ablation catheter is then pushed into the guide catheter 7 I inside, when the head end of the guiding catheter reaches the specified position 7, I ablation catheter may be pushed out of the guiding catheter end opening 7, to restore pre-deformation. 如图16A所示,将远端汇集于消融段头端17的两条独立结构8预制成类似纺锤形,将该消融导管I压入导引导管7内,由于导引导管7的限制,预制成纺锤形的两条独立结构8的中间部分将相互靠拢。 16A, the distal end of the ablation segments collected in the head end 17 of the two separate structures similar preformed spindle 8, the ablation catheter within the guiding catheter into the press I 7, the guide catheter limitations 7, fusiform preformed intermediate portion 8 of the two individual structures will move towards each other. 如图16B所示,当导引导管7到达肾动脉a在主动脉b上的开口处时,将消融段6从导引导管7头端开口内推送出来,此时两条独立结构8将恢复成预制的类似纺锤形,附着射频消融电极头9的突出部分将优先与血管壁接触。 16B, the conduit 7 when the guide reaches the opening of a renal artery in the aorta b, the ablation segment 6 is pushed out from the end opening of the guide duct 7, then recover two separate structures 8 similar spindle into a preform, radiofrequency ablation tip attachment projection 9 will preferentially contact with the vessel wall. 如图16C所示,当可控弯曲段5预制成“C”形时,导引导管7可在接近肾动脉a在主动脉b上的开口处时即将消融段6从导引导管7头端开口内推送出来,由于可控弯曲段5的“C”形弯曲的存在,消融段6也能够顺利从主动脉b进入肾动脉a。 16C, when the controllable preformed curved section 5 "C" -shaped, the guide catheter ablation is about 7 may be near a renal artery in the opening paragraph b aorta from the guide catheter 6 7 push out the end opening, since the presence of controlled deflection shaped bent "C" section 5, the ablation segment 6 can smoothly enter the renal artery from the aorta a b. 图16是以远端连接于消融段头端17的两条独立结构8为例进行设计方案说明的,因此不局限于两条独立结构8的情况,也不局限于独立结构8远端连接于消融段头端17这一种两两独立结构8的连接方式,对于多于两条独立结构8的情况和两两独立结构8其他的连接方式也同样适用,例如对于相互分离的独立结构8,需要将独立结构8预制成以头端及其附近位置相互远离最为明显的状态,然后压入导引导管7,又例如对于独立结构8的中间某处连接在一起远端再相互分离的情况,需要将独立结构8远端到连接点18之间的部分预制成以头端及其附近位置相互远离最为明显的状态,而将独立结构8近端到连接点18之间的部分预制成纺锤形,然后压入导引导管7,再例如对于部分相对的独立结构8相互分离而部分相对的独立结构8的远端连接于消融段头端17的情况,需要将相互分离 FIG 16 is connected to the distal end of the ablation head section 8 of the two individual structures 17 described design example, and therefore the case is not limited to two separate structures 8, 8 is not limited to an independent structure is connected to the distal end an ablation head end segment 17 which separate a two-way two connecting structure 8, for the case of more than two separate structures 8 and 8 pairwise independent of other connection structures are also applicable, for example, 8 independent structures separated from each other, 8 needs to be an independent structure preformed in a position near the head end and apart from each other most significant state, and then pressed into the guide catheter 7, for example, and then separated from each distal end connected to the intermediate structure 8 independently somewhere in the case where needs to be an independent structure to the connection point 8 the distal end portion of the preform to a position near a head end and apart from each other between the most significant state 18, while the proximal end to separate the structure 8 is connected between the point portion of the preform 18 into the spindle, and then pressed into a guide catheter 7, for example, another portion 8 opposing each other independent of the structure of the distal end portion opposing separation independent structure 8 is connected to the case end 17 of the ablation segment head needs to be separated from each other 独立结构8预制成以头端及其附近位置相互远离最为明显的状态,而将远端连接于消融段头端17的独立结构8预制成纺锤形,然后压入导引导管7。 8 independent structure preformed in a position near the head end and apart from each other most significant state, and the distal end of the ablation segment is connected to the head end 17 of the individual structures preformed spindle 8, and then pressed into a guide catheter 7. 此外也可以在导引导管7的头部设置与独立结构8相对应的斜孔74或/和侧槽76,这样在不将消融段6前推出导引导管7的情况下,也可以实现独立结构8恢复预制形变。 Further the head may be provided with a guide catheter 7 to 8 individual structures corresponding slant holes 74 and / or side groove 76, so that the ablation section 6 is not the case before Release 7 of the guide catheter, may also be implemented independently 8 prefabricated structural deformation recovery.

[0070] 图17、图18显示了本发明的实施例中通过结构设计改变消融导管I和导引导管7硬度分布的方式。 [0070] FIG. 17, FIG. 18 shows how the embodiment of the present invention, by changing the structural design of the ablation catheter I and guiding catheter 7 hardness distribution. 这种通过结构设计改变消融导管I和导引导管7硬度分布的方式并不要CN 102908188 A This change ablation catheter I and guiding catheter 7 through the design method is not distributed to the hardness CN 102908188 A

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求各个部分的制造材料本身的硬度不同。 Materials of different hardness of each portion of the request itself.

[0071] 如图17A、图17B所示,在消融导管I内部设置图17A和图17B所示的鸡肋样结构,即间隔d5距离设置一个横截面为图17B所示的结构,该结构中斜线表示的部分被有一定弹性的材料填充,优选高分子聚合物,空白区域al在消融导管I内将形成ー个腔室,主要用于导线、细导管、光纤等走行,当然空白区域al并不局限于圆形,也不局限于仅有ー个腔室,根据情况可以设置成其他形状(例如椭圆形、长方形等),也可以设置更多的腔室分别走行不同的构件。 [0071] FIG. 17A, 17B, chicken-like structure shown in the ablation catheter I provided inside FIGS. 17A and 17B, i.e. spaced a distance d5 is provided a cross-sectional structure shown in FIG. 17B, the Inclined is partially filled with a material line represents a certain elasticity, preferably a polymer, a blank area in the ablation catheter al I formed ー chambers, mainly used for wire, thin catheter, an optical fiber traveling, and of course a blank area al is not limited to a circle, it is not limited only ー chambers, may be provided in some cases other shapes (e.g., oval, oblong, etc.) may be provided additional chambers, respectively, along different rows member. 如图17A、图17B所示,空白区域bl在消融导管I内也将形成ー个腔室,也可走行导线、细导管、光纤等,这样空白区域al、bl就能够分别走行不同的构件,当然空白区域bl并不局限于半圆形,也不局限于仅有ー个腔室,根据情况可以设置成其他形状(例如椭圆形、长方形等),也可以设置更多的腔室分别走行不同的构件。 As shown in FIG. 17A, 17B, a blank area bl within the ablation catheter I may also be formed ー chambers, may take the row conductor, thin catheter, an optical fiber, so that the blank area Al, bl can each traveling different components, of course, the blank area is not limited to semicircular bl, is not limited only ー chambers, it may be provided in some cases other shapes (e.g., oval, oblong, etc.) may be provided additional chambers, respectively, traveling different components. 如图17A所示,由于在d5所包括的区域内缺乏图17B中d3和d4所包含区域内的弧形结构,因此在纵轴方向上,每个d5所包括的区域将容易发生弯曲,所有d5所包括的区域的弯曲将使图17A所示的结构形成整体弯曲。 17A, due to the lack in the area included d5 d3 and d4 in FIG. 17B contained arcuate configuration in the region, in the longitudinal direction so that each area included d5 will readily bent, all d5 curved region included in the structure shown in FIG 17A will be formed entirely curved. 类似地,如图17(:所示,(13、(14、(13'、(14'所包括的区域内设置两个图17B中bl样的空白区域,即空白区域bl、b2,而此时空白区域al位于空白区域bl、b2之间,处在dl所包括的区域内(主要在d2和d2'围成的区域内),图17A中d6所包括区域内的结构将被图17C所示的结构替代,而图17A中d5所包括区域内的结构将是图17C中dl所包括区域内的结构的延伸;空白区域al在消融导管I内将形成ー个腔室,用于导线、细导管、光纤等走行,当然空白区域al并不局限于椭圆形,也不局限于仅有ー个腔室;空白区域bl和b2在消融导管I内也将形成两个腔室,也可走行导线、细导管、光纤等,当然空白区域bl和b2并不局限于半圆形,也不局限于分别仅有ー个腔室;由于在d5所包括的区域内缺乏图17C中d3、d4、d3'、d4'所包括区域内的弧形结构,因此在纵轴方向上,每个d5所包括的区域将容易 Similarly, FIG. 17 (:, the (13, (14, (13 ', (14' disposed within the area in FIG. 17B comprises two bl-like blank area, the blank area bl i.e., B2, and this al blank region located blank area BL, between b2, in (mainly in the d2 and d2 'area surrounded) within a region included dl, FIG. 17A d6 included in the structure of FIG. 17C is the area the alternative configuration shown, and in FIG. 17A d5 structure included in the region will be in the region of the extension structure in FIG. 17C included dl; al blank area in the ablation catheter ー I formed a chamber for the wire, thin tube, an optical fiber traveling course al blank area is not limited to an ellipse, not limited to only ー chambers; blank areas bl and b2 two chambers will be formed in the ablation catheter I, may be traveling wires, thin tube, fiber or the like, of course, the blank area is not limited to semicircular bl and b2, are not limited only ー chambers; lack the region d5 in FIG included. 17C d3, d4, d3 ', d4' of the arcuate configuration in the region comprises, in the longitudinal direction so that each area included d5 will readily 发生弯曲,所有d5所包括的区域的弯曲将使图17A所示结构形成整体弯曲,此时由于d5两侧均缺少支撑结构,因此可以发生双向弯曲,且通过调整空白区域bl和b2的大小将使得向两个方向弯曲的难易程度不同;当然,类似地也可以在三个不同方向上设置三个图17B所示意的bl样空白区域,以实现至少三个方向的弯曲,且这种设计结构还可以以此类推。如图17D、图17E所示,当消融导管I某些部分的横截面不为圆形时,鸡肋样结构同样可以在这些消融导管I部分中实现,图17D、图17E以半圆形结构为例说明了鸡肋样结构在除圆形之外的其他形状中的实现方式,根据弯曲方向的不同,空白区域al和bl安排的位置有所不同。例如,如图17D所示,将空白区域bl安排在空白区域al的左边,图17A中d6所包括区域内的结构将被图17D所示的结构替代,而图17A中d5所包括区域内的结构将 Bent, curved region included all d5 will form an integral structure shown in FIG. 17A is bent, this time due to the lack of both sides of the support structure d5, thus biaxial bending can occur, and the blank area by adjusting the size of the bl and b2 two different directions so that the bent degree of difficulty; of course, may be similarly provided three bl like blank area in FIG. 17B schematically three different directions, in order to achieve bent at least three directions, and this design structure may also and so on. as shown in FIG 17D, as shown, when the cross section of the ablation catheter I some portion is not circular, chicken-like structure can also be implemented in the ablation catheter of FIG. 17E I section, FIG. 17D, FIG. 17E illustrates an example in a semicircle-like chicken in other implementations other than circular in shape, the different positions, the blank area al and bl arrangements differ according to the bending direction. For example, as shown in FIG 17D as shown in the blank area in the left margin arrangements bl al., FIG. 17A d6 region comprising the structure in the alternative configuration is shown in FIG. 17D, FIG. 17A and d5 included in the region of the structure 图17D中dl所包括区域内的结构的延伸,这样整个立体结构将容易向空白区域bl侧弯曲;如图17E所示,将bl安排在al的右边,图17A中d6所包括区域内的结构将被图17E所示的结构替代,而d5所包括区域内的结构将是图17E中dl所包括区域内的结构的延伸,这样整个立体结构将容易向空白区域bl侧弯曲。在图17所示的结构中,通过改变空白区域al、bl、b2的大小、数量,以及通过改变dl、d2、d3、d4、d5、d6的大小,可以实现各段硬度的不同,例如在图17A中的某一段加宽dl,縮小d3或d4将使得这一段不容易形变,再例如某一段加宽d5将使得,这一段更容易形变;通过改变不同段内空白区域al和bl区域的相对位置可以实现不同段非同向弯曲,例如将图17A所示意结构的下半部水平旋转180度,将使得下半部空白区域bl在图17A中的箭头侧,这样改进后的结构将有助于实现“S”形弯 FIG. 17D dl structure extends within the region comprising the entire three-dimensional structure so that it will be readily bent toward the side bl blank area; FIG. 17E, the right to arrange bl al., FIG. 17A d6 structure in the region comprising the FIG 17E is shown in an alternative structure, the structure including the d5 would be in the region of the extension structure in the area included dl FIG. 17E, so that the entire three-dimensional structure will be readily bent toward the side bl blank area. in FIG. 17 structure illustrated by changing the blank area al, bl, size b2, the number, and by changing dl, d2, d3, d4, d5, size d6 may be achieved in different segments hardness, for example, in FIG. 17A DL widening certain period, d3 or d4 reduced so that this section will not be easily deformed, for example, then a certain period so that the widened d5, which is more easily deformed section; may be achieved by changing the relative position of the different segments of the blank area of ​​the area al and bl different segments unusual bent, for example, a 180 degree rotation of the lower half of Figure 17A a schematic configuration of a level, such that the lower half of the blank area bl arrow in FIG. 17A side, so that the structure will contribute to improved " S "shaped bend .

17总之,鸡肋样结构的实质是通过选择性的减少或/和增加某些导管小段的内部结构进而选择性的降低或/和提高某些导管小段内部某一侧或者某几侧的抗弯曲能力,以使得导管更易向某些方向弯曲或/和形成某些弯曲形态。 17 In sum, the chicken-like structure is reduced by further selective reduction and / or increase the internal structure of some selective subparagraph catheter / bending resistance and enhance some small pieces of one side or the catheter inner side or of certain , so that the catheter is more flexible and / or curved configuration to form certain certain direction.

[0072] 图18显示了本发明的实施例中另一种通过改变结构设计进而改变硬度分布使弯曲更易实现的设计方式。 [0072] FIG. 18 shows an embodiment of the present invention, another further vary the hardness distribution such that more curved design achieved by changing the design. 该设计结构是鸡肋样结构在中空管状结构中的实现方式,该种结构优选用于中空管样结构(例如导引导管7等)。 The structure is designed like chicken implementation structure in the hollow tubular structure, the seed structure is preferably a hollow tube-like structure (e.g. a guide catheter 7 and the like). 该结构主要通过改变消融导管I和导引导管7管壁中的金属丝网在不同导管小段内的排布或通过改变消融导管I和导引导管7管壁在不同导管小段中的厚度来实现的,当然这里所述的金属丝网应该理解为加固导管管壁硬度的设计结构,例如也可以是高分子材料网等,因此该种设计的实质是通过选择性的减少或/和增加某些导管小段管壁的结构进而选择性的降低或/和提高某些导管小段管壁的某一侧或者某几侧的抗弯曲能力,以使得导管更易向某些方向弯曲或形成某些弯曲形态。 By changing the structure of the main wire mesh ablation catheter I and guiding catheter wall 7 is arranged in the different thickness of the conduit or conduits of small pieces I and guiding catheter wall 7 in subparagraph different catheters ablation is achieved by changing the of course here the wire mesh should be understood that the design structure of the catheter wall reinforcement hardness, for example, a polymer material may be a net, so the essence of the kind designed by selective reduction and / or increase certain subparagraph catheter wall structure further selective reduction and / or improved resistance to bending one side or several sides of a wall of some small pieces of the catheter, so that the catheter is more flexible or curved configuration formed to some certain direction. 图18是以改变消融导管I或导引导管7管壁中的金属丝网在不同导管小段内的排布为例进行说明的。 FIG 18 is a change I ablation catheter or guide wire mesh conduit 7 is arranged in the wall of the small pieces of different catheters described example. 如图18A所示,图中网线表示金属丝网,从图18A的左下图可以看到,导管管壁中的金属丝网是完全覆盖导管管壁的,从图18A的左上图可以看到,导管的一侧管壁中没有金属丝网,将两个导管小段间隔相叠在一起,构成图18A的右图所示的结构,由于上方的一小段导管的一侧管壁中没有金属丝网,因此导管更易向没有金属丝网的一侧弯曲。 18A, FIG cable represents a metal mesh, can be seen from the lower left of FIG. 18A, the wire mesh conduit wall is completely covered by the catheter wall, it can be seen from the upper left of FIG. 18A to FIG, a side wall of the catheter without wire mesh, the two small pieces of the catheter spaced stacked together to form the right as shown in FIG. 18A configuration, the short side wall of the catheter over the wire mesh is not , the catheter is more flexible and therefore not to the side of the wire mesh. 当然也不局限于导管的一侧管壁中没有金属丝网的设计方式,如图18D所示,在两个有完整的金属丝网的导管小段之间有四条“S”形金属丝fl、f2、f3、f4,可以在fl、f2间和f3、f4间设置金属丝网,而在f2、f3间和fl、f4间不设置金属丝网,这样导管更易向没有金属丝网的两侧弯曲,同理也可以在每相邻两个“S”形金属丝间只设置一半的金属丝网,这样导管更易向没有金属丝网的四个方向弯曲,还可以只有四条“S”形金属丝而没有金属丝网,这样整个导管将容易向多个方向弯曲。 Of course, not limited to a side wall of the catheter without wire mesh design approach, shown in FIG. 18D, there are four "S" shaped wire fl between two small pieces of the catheter has a complete wire mesh, f2, f3, f4, can f3, f4 between the wire mesh disposed between fl, f2, and a wire mesh is not provided between f2, f3, and inter-fl, f4, so that the catheter is not more sides of the wire mesh bending, similarly may be "S" shaped wire provided only between half of each adjacent two wire mesh, so that the catheter is more flexible in the four directions without metal mesh, can only four "S" shaped metal without the wire the wire mesh so that the entire catheter to be easily bent in multiple directions. 此外也不局限于某些导管小段管壁的某一侧或某几侧没有金属丝网的情况,这可以通过改变金属丝网的孔径、密度、金属丝的宽窄等方式实现某些导管小段管壁的某一侧或某几侧较其他导管壁软或硬;根据情况“S”形金属丝的数量可以调整,同时“S”形金属丝也可以是其他形态,例如“Z”形等。 Also not limited to one side of the conduit or a few small pieces of the side wall is not certain where the wire mesh, which may be implemented some small pieces of the catheter tube by varying the aperture wire mesh density, the wire width, etc. one or a few side than the other side wall of the soft or hard catheter wall; number of shaped wire "S" can be adjusted according to circumstances, while "S" shaped wire may be other shape, for example, "Z" shape. 图18A的结构可以按照图18B所示的侧面观图排布,这样整个导管段的弯曲方向将是一致的;图18A的结构可以按照图18C所示的侧面观图排布,这样整个导管段上下部分的弯曲方向不一致的,通过这种方式就可以借助一根导向丝70实现复杂弯曲,例如将导向丝70从图18C中d3和d3'相交的区域穿过将更易实现“S”形弯曲。 Structure of FIG. 18A may be up view of a side according to the arrangement shown in FIG. 18B, so that the bending direction of the entire section of the catheter will be consistent; structure of FIG. 18A may be arranged in accordance with the side view shown in FIG. FIG. 18C, so that the entire tube length inconsistent bending direction of the upper and lower portions, this embodiment can be implemented by means of a complex curved guide wire 70, for example, the guide wire 70 'passes through the intersecting regions will be more readily achieved "S" from the drawing d3 and d3 shaped bend 18C . 如图18B和图18(:所示,还可以通过调整(11、(13、(13'、(14、(15的宽度来改变导管各段弯曲的难易程度。此外整个结构也不局限于导管横截面为圆形的情况,导管横截面为半圆、正方形等形状时仍然可以按照该思路进行设计,但此时需要考虑到这些形状对导向丝70以及鸡肋样结构本身硬度的影响。 FIG. 18B and FIG. 18 (: as shown, can also be changed for each segment ease by adjusting the curved conduit (11, (13, (14 width (13 ', (the entire structure 15 is not limited to the addition. circular cross-section of the conduit, the cross section of the catheter can still be designed according to the idea when semicircular, square and other shapes, but this time need to consider the effect of these shapes on a guidewire-like structure 70 and the chicken itself hardness.

[0073] 图17、图18所显示的通过结构设计改变消融导管I和导引导管7硬度的方式,还可以通过改变制造材料的硬度来实现,例如导管各小段的横截面可以均是图18B的设计方式,但是某些小段的横截面上d3、d4所包括的区域制造材料较另一些小段硬,那么这些小段将不容易发生弯曲。 [0073] FIG. 17, the design shown in FIG. 18 to change the way the ablation catheter I and guiding catheter 7 hardness, may also be achieved by changing the hardness of the material for producing, for example, the cross-section of the duct can be each individual lengths FIG 18B design approach, but some small pieces of the cross-section d3, d4 region included in the manufacturing materials other than hard small pieces, then these small pieces will not easily bent.

[0074] 图19是以两条独立结构8远端连接于消融段头端17为例,显示了本发明的实施例中如何通过调整独立结构8的硬度分布使设计的形变更易实现。 [0074] FIG. 19 is a structure of two separate 8 is connected to the distal end of the ablation head section 17 as an example, shows an embodiment of the present invention, the design of how to make the distribution of the hardness by adjusting the deformation of the individual structures 8 easier to implement. 如图19A所示,两条独立结构8a、8b弯曲形态彼此相互对称,为了方便为半圆柱形的两条独立结构8a、8b向外相对隆起,可以采用图17或/和图18所示意的鸡肋样结构,当采用图17所示意的鸡肋样结构时,独立结构8可采用图17D所示的设计方案,其中虚线cc所示的横截面的形态优选为图17D所示;当采用图18所示意的鸡肋样结构时,独立结构8中的空白部分应理解为独立结构8管壁间隔一定距离的结构硬度降低,例如通过去掉金属丝网、改变金属丝网的密度等。 19A, two separate structures 8a, 8b bent shape symmetrical to each other, for convenience as two separate semi-cylindrical structure 8a, 8b opposite outward bulge, may be employed FIG. 17 or / and 18 illustrated in FIG. chicken-like structure, when a chicken-like configuration illustrated in FIG. 17, the structure 8 can be independent design shown in FIG. 17D, wherein the shape of the cross section shown in phantom as shown in FIG cc, preferably 17D; FIG. 18 when employed when the illustrated tasteless like structure, a blank portion 8 to be understood as an independent structure standing structure 8 at a distance from the wall structure of reduced hardness, for example, by removing a metal mesh, a metal mesh density change. 如图19B、图19C、图19D所示,两条独立结构8的弯曲形态也可不对称,这对于独立结构8多于两条时是十分必要的,它有助于使得消融点处在不同的肾动脉横截面上;与图19A所示意的鸡肋样结构类似,图19B、图19C、图19D所示意的设计方案也可采用图17或/和图18所示意的鸡肋样结构,为了实现不同的弯曲形态,可以通过调整各独立结构8上鸡肋样结构的布置方式实现各段硬度的不同,在曲率较大的地方硬度优选较小,更易实现弯曲。 FIG. 19B, FIG. 19C, FIG. 19D, two independent structures 8 may also be a curved shape asymmetry, which for more than 8 when two independent structures is necessary, so that it helps the ablation points are in different renal artery cross-section; FIG. 19A is similar to the illustrated structure like chicken, 19B, FIG. 19C, FIG. 19D is a schematic of the design of FIG. 17 may be employed and / or 18 illustrated in FIG tasteless like structure, in order to achieve different the curved configuration can be achieved by adjusting the arrangement of each structure is independently chicken-like structure 8 of different hardness segments, where a smaller curvature preferably greater hardness, bending more easily achieved. 图19中独立结构8a、8b的空白部分表示各独立结构8上硬度较小的部分,因此通过调整独立结构8a、8b上空白部分的大小、形态、分部密度等能够改变鸡肋样结构的硬度分布,进而改变弯曲形态。 FIG independent structure 8a 19, the blank portion 8b represents hardness smaller portion 8 each independently structure, by adjusting the stiffness can be changed independently of the structure of the chicken-like structure 8a, 8b on the size of the blank portion, morphology, density Division distribution, thereby changing the curved shape. 如图19B所示,在独立结构8a中射频消融电极头9至独立结构8a尾端的部分和独立结构8b中射频消融电极头9至消融段头端17的部分曲率较大,因此空白部分的也较大和较密。 19B, the configuration in separate radiofrequency ablation portion 8a and 8b independently tip structure to a separate structure 9 in the tail end 8a radiofrequency ablation tip 9 to the ablation head end section 17 of the larger curvature portions, and therefore the blank portion larger and more dense. 类似地,图19C中,为了实现独立结构8形变后两个射频消融电极头9到消融段6长轴中心线的距离相等,在两条独立结构8长度相等的情况下,独立结构8b设计成了近端不易弯曲而远端及中间部分易发生弯曲,因此独立结构8b的远端及中间部分空白部分也更密集,使其更易弯曲。 Similarly, FIG. 19C, in order to achieve two independent structural deformation after 8 radiofrequency ablation tip 9 to the ablation segment is equal to the centerline distance of the major axis 6, two independent structures in length is equal to 8, designed as an independent structure 8b stiff proximal portion and a distal end and an intermediate bent easily, so the distal end and the intermediate portions 8b independent structure more dense portion of the blank, making it easier to bend. 图19D中,独立结构8形变后两个射频消融电极头9到消融段6长轴中心线的距离不相等,在两条独立结构8长度相等的情况下,独立结构8的中间隆起最明显的部分在两条独立结构8上的长度不同,独立结构Sb的中间隆起最明显的部分较长,这就要求独立结构8b的其他部分曲率更大,更易弯曲,因此独立结构8b的远端及近端的空白部分也更大、更密集。 In FIG. 19D, the deformation of two individual structures 8 radiofrequency ablation electrodes 6 from the head 9 to the ablation segment is not equal to the major axis centerline, two independent structures in length is equal to 8, the intermediate structure 8 independently raised most obvious portions of different lengths in two separate structure 8, the structure of Sb independent intermediate elevations most significant longer portion, which requires the structure of other parts 8b independently of curvature greater, more flexible, and therefore the distal end 8b of the individual structures and near blank also part of the end of the larger and more dense. 如图19所示,空白部分的形状也可以是多变的,可以是图19A、图19C、图19D所示的形状,也可以是图19B所示的形状,当然技术人员还可以根据具体实际设计其他形状。 19, the shape of the space portion may be varied, and may be FIGS. 19A, 19C, 19D shown in FIG shape, may have a shape shown in FIG. 19B, of course, also the art according to specific actual design other shapes. 图19是以两条独立结构8为例进行设计方案说明的,因此不局限于两条独立结构8的情况,对于多于两条独立结构8的情况也同样适用。 FIG 19 is an example for two independent design structure 8 described and is therefore not limited to the case where two separate structure 8, for the case of more than two separate structure 8 also apply. 此外图19中独立结构8上的空白部分应理解为独立结构8间隔一定距离的结构硬度降低,这种硬度下降不仅可以通过改变结构设计的方式实现也可以通过改变材料硬度的方式实现。 Further blank portion 19 on a separate structure 8 to be understood as an independent structure to reduce a distance from 8 structural rigidity, this decrease in hardness can be achieved not only by changing the material hardness manner by changing the way of the design. 对于技术人员需要独立结构8形成其他弯曲形态的情况,可以对图19中独立结构8的空白部分进行相应调整。 For the skilled person need for a separate structure 8 formed of other curved form, can be adjusted independently of the structure of the blank portion 19 in FIG. 8.

[0075] 图21是以两条独立结构8为例,显示了本发明的实施例中独立结构8相互分离时如何通过调整独立结构8的硬度分布使设计的形变更易实现。 [0075] FIG. 21 is an example two separate structures 8, shows the deformation when an independent structure in Example 8 independently from each other how to adjust the design of the structural stiffness distribution such that 8 of the embodiment of the present invention is easier to implement. 图21中独立结构8上的空白部分表示的意义应理解为独立结构8间隔一定距离的结构硬度降低,这种硬度降低不仅可以通过改变结构设计的方式实现也可以通过改变材料硬度的方式实现,因此可以通过调整空白部分的大小、形态、分布密度等改变独立结构8的硬度分布使其更易弯曲成为所需要的形态。 Significance FIG blank portion 21 on the individual structures 8 are understood as an independent structure 8 spaced apart structural rigidity decreases, which decrease hardness can be achieved not only by changing the material hardness manner by changing the way of the design, Thus by adjusting the size of the blank portion, shape, density distribution changing hardness distribution independent structure makes it easier to 8 bent into the desired shape. 与图19所示意的独立结构8连接于消融段头端17时的结构设计思路相似,图21所示意的设计方案优选地采用鸡肋样结构,采用图17所示或/和图18所示的鸡肋样设计均可。 FIG 19 is a schematic structure 8 is connected to a separate section similar to the ablation head end 17 of the structural design ideas, Fig 21 a schematic design preferably employs chicken-like structure, shown in Fig employed and / or in FIG. 17 and FIG. 18 chicken-like design can be. 如图21所示,在靠近独立结构8头端的部分,空白部分优选被设置在独立结构8靠消融段6中心线的部分,而在独立结构8的中间部分和尾部,空白部分优选被设置在独立结构8远离消融段6中心线的部分;当然也可以将空白部分均设置在独立结构8靠消融段6中心线的部分或独立结构8远离消融段6中心线的部分。 21, an independent structure in the portion near the head end 8, the blank portion is preferably provided in a separate structure 8 against the ablation segment center line part 6, and an independent structure in a middle portion and a tail, a blank portion 8 is preferably provided 8 independent structure portion 6 away from the centerline of the ablation segments; blank portion may of course be individual structures are disposed in a portion 8 on an independent structure or portion of the ablation segments of the center line 6 remote from the ablation segment 6 8 centerline. 图21B、图21C是以两条独立结构8为例说明如何实现消融点在不同的肾动脉横截面上。 21B, the structure of FIG 21C is a two separate 8 an example of how to achieve ablation points different cross section in the renal artery. 如图21B所示,两条独立结构8a、8b As shown in FIG. 21B, two independent structures 8a, 8b

19的长度不等,由于两条独立结构8的长度不同而射频消融电极头9均设置在每条独立结构8的头部,因此能够实现消融点在不同的肾动脉横截面上。 19 unequal length, due to the different lengths of the two independent radiofrequency ablation structure 8 and 9 are provided at the tip of the head of each independent structure 8, ablation points can be realized in different cross section renal artery. 如图21C所示,两条独立结构8a、8b的长度也可相等且内部结构基本是镜面对称的,只是射频消融电极头9的附着位置有所不同,独立结构8a上的射频消融电极头9a更靠近独立结构8的远端,通过这种方式也能够实现消融点在不同的肾动脉横截面上。 Shown, two separate structures 8a, 8b is also equal to the length and the internal structure is substantially mirror-symmetrical in FIG. 21C, but the attachment position of radiofrequency ablation tip 9 is different, independent radio frequency ablation tip structures 8a 9a 8 is closer to the distal end of the separate structure, it is possible to achieve in this way the ablation of the renal artery at different points in the cross section. 图21是以两条独立结构8为例进行设计方案说明的,因此不局限于两条独立结构8的情况,对于多于两条独立结构8的情况也同样适用。 FIG 21 is an example for two independent design structure 8 described and is therefore not limited to the case where two separate structure 8, for the case of more than two separate structure 8 also apply. 此外对于技术人员需要独立结构8形成其他弯曲形态的情况,可以对图21中独立结构8的空白部分进行相应调整。 In addition to the skilled person need for a separate structure 8 formed of other curved form, can be adjusted independently of the blank portion 21 in the configuration of FIG. 8.

[0076] 图22、图23是以两条独立结构8为例,显示了独立结构8的中间某处连接在一起远端再相互分离时如何通过调整独立结构8的硬度分布使设计的形变更易实现。 [0076] FIG. 22, FIG. 23 is an example two separate structures 8, somewhere in the middle shows the structure 8 independent distal end connected to each other and then adjust how the hardness distribution independent separation structure 8 so shaped design changes easy to implement. 图23中独立结构8上的空白部分表示的意义应理解为独立结构8间隔一定距离的结构硬度降低, 这种硬度降低不仅可以通过改变结构设计的方式实现也可以通过改变材料硬度的方式实现,因此可以通过调整空白部分的大小、形态、分布密度等改变独立结构8的硬度分布使其更易弯曲成为所需要的形态。 FIG 23 Significance blank portion 8 independently represent configuration to be understood as a distance from an independent structural rigidity structure 8 is reduced, this reduction in hardness can be achieved not only by changing the material hardness manner by changing the way of the design, Thus by adjusting the size of the blank portion, shape, density distribution changing hardness distribution independent structure makes it easier to 8 bent into the desired shape. 如图22所示,当独立结构8为两条时,可将两条独立结构8的连接点18做成连接关节,连接关节可通过闩体e将半圆柱形的独立结构8a、8b连接在一起,并能相对转动;当推送消融导管I或回退导引导管7使连接点18处的连接关节接触到导引导管7头部斜孔74间的连接部分75时,两条独立结构8的远端将相互远离,附着于独立结构8头部的射频消融电极头9将与血管壁接触;为了使射频消融电极头9与血管壁接触面积更大,如图22所示,两条独立结构8的头部半圆柱形的方向为横向的半圆柱形,而独立结构8的其他部分为纵向的半圆柱形;为了使图22所示的弯曲形态更容易形成,同样也可以采用鸡肋样结构,靠外的独立结构8b由于弯曲开口向下,因此可以间隔一定距离在独立结构8b的下侧设置硬度减弱的部分,同样地,靠内的独立结构Sb由于弯曲开口向上,因此可以间隔一 22, when an independent structure 8 is two, the two separate structural connection point 188 may be connected to make a joint, the joint can be connected to a separate semi-cylindrical structure 8a, 8b connected to the latch body by e together, and to the relative rotation; when I push the ablation catheter or a guide catheter 7 backoff articulating the connecting point 18 is connected to the contact portion 74 of the guide catheter inclined hole 75 of the head 7, two separate structures 8 the distal end away from each other, in a separate structure attached to the RF ablation tip 8 of the head in contact with the vessel wall 9; 9 radiofrequency ablation in order to make contact with a larger area of ​​the vessel wall, the electrode tip shown in Figure 22, two separate semi-cylindrical configuration of the transverse direction of the head 8 of the semi-cylindrical, while other portions of the individual structures 8 is a longitudinal semicylindrical; to make a curved form shown in Figure 22 is easier to form, like also may be employed tasteless structure, independent of the structure against the outer opening 8b by bending downwardly, and therefore may be spaced a distance from the lower side portion of reduced hardness 8b is an independent structure, in the same manner, by independent structures within the upwardly opening Sb due to the bending, can be spaced a 距离在独立结构8a的上侧设置硬度减弱的部分;若采用图17所示意的鸡肋样结构,图22中虚线ccl、cc2横截面的截面放大图即为图22中上、下两幅半圆形小图,则图17A中d6所包括区域在图22中独立结构8a、8b的截面横图即分别为图22中下、上两幅半圆形小图。 From the hardness of weakening provided on the side portions of the individual structures 8a; use of a chicken-like configuration illustrated in FIG. 17, the broken line in FIG CCL 22, the cross-sectional cc2 is the sectional enlarged view in figure 22, the two semi-circular shaped panels, in the FIG. 17A d6 region included in an independent structure 22 in FIG. 8a, 8b is a cross-sectional drawing of FIG i.e. under 22, the two small semicircular FIG. 与图19所示意的独立结构8连接于消融段头端17时的结构设计思路相似,图23所示意的设计方案也优选采用鸡肋样结构,采用图17所示或/和图18所示的鸡肋样设计均可。 FIG 19 is a schematic structure 8 is connected to a separate section similar to the ablation head end 17 of the structural design ideas, FIG. 23 is also a schematic design chicken-like structure is preferably used, the use of FIG. 17 and / or 18 shown in FIG. chicken-like design can be. 如图23所示,在靠近独立结构8头端的部分,空白部分优选被设置在独立结构8靠消融段6中心线的部分,在其后到连接点18的部分,空白部分优选被设置在独立结构8远离消融段6中心线的部分,在连接点18到独立结构8末端的部分,空白部分优选被设置在独立结构8靠消融段6中心线的部分;当然也可以将空白部分均设置在独立结构8靠消融段6中心线的部分或独立结构8远离消融段6中心线的部分,且技术人员可根据情况对空白部分的设置位置进行调整。 23, in an independent structure portion 8 near the end, part of the blank portion is preferably provided on the centerline of the ablation segment portion 6 independent structure 8, thereafter the connection point 18, the blank portion is preferably provided in a separate 8 away from the part of the ablated structure centerline section 6, the portion 18 is connected to a separate point of the structure of the terminal 8, a blank portion is preferably provided in a separate structure 8 against the ablation segment 6 portion of the centerline; of course also be provided in the blank parts are independent structural part 8 against the ablation segment 6 or an independent structure portion 6 remote from the center line 8 of the centerline of the ablation segment, and the skilled person can adjust the position of the blank portion is provided depending on the situation. 图23B、图23C是以两条独立结构8为例说明如何实现消融点在不同的肾动脉横截面上。 23B, and 23C are two independent structures 8 an example of how to achieve ablation points different cross section in the renal artery. 如图23B所示,两条独立结构8a、8b的长度不等,但连接点18到独立结构8尾端的部分长度是相等的,由于两条独立结构8的长度不同而射频消融电极头9均设置在每条独立结构8的头部,因此也可实现消融点在不同的肾动脉横截面上。 As shown in FIG. 23B, two independent structures 8a, 8b of unequal length, but the length of the connecting portion 18 to a separate point of the trailing end of the structure is equal to 8, due to the different lengths of the two individual structures 8 and 9 are radiofrequency ablation tip each of the individual structure provided in the head 8, so the ablation can be achieved at different points in the cross section of the renal arteries. 如图23C所示,两条独立结构8a、8b的长度也可相等且内部结构基本是镜面对称的,只是射频消融电极头9的附着位置有所不同,独立结构8a上的射频消融电极头9a更靠近独立结构8的远端,通过这种方式能够实现消融点在不同的肾动脉横截面上。 Shown, two separate structures 8a, 8b is also equal to the length and the internal structure is substantially mirror-symmetrical in FIG. 23C, but the attachment position of radiofrequency ablation tip 9 is different, independent radio frequency ablation tip structures 8a 9a closer to the distal end 8 of the individual structures, the ablation can be achieved in this manner at different points of the cross section of the renal artery. 图23是以两条独立结构8为例进行设计方案说明的,因此不局限于两条独立结构8的情况,对于多于两条独立结构8的情况也同样适用。 FIG 23 is an example for two independent design structure 8 described and is therefore not limited to the case where two separate structure 8, for the case of more than two separate structure 8 also apply. 此外对于技术人员需要独立结构8形成其他弯曲形态的情況,可以对图23中独立结构8的空白部分进行相应调整。 In addition to the skilled person need for a separate structure 8 formed of other curved form, can be adjusted independently of the blank portion 23 in the configuration of FIG. 8.

[0077] 对于部分独立结构8远端连接于消融段头端17而部分独立结构8相互分离的情况,可以将图19、图21所示意的独立结构8的设计方案进行融合,即远端连接于消融段头端17的独立结构8采用图19所示意的设计方案,而相互分离的独立结构8采用图21所示意的设计方案。 [0077] For some freestanding structure 8 is connected to the distal end of the partial structure 8 independently from each other head end of the ablation segment 17, 19 can be separate structures 21 illustrated in FIG. 8 designs are fused, i.e., distal connector an ablation segment at the head end 8 of the individual structures 17 using the design illustrated in FIG. 19, mutually separate and independent configuration 21 of FIG. 8 using the design illustrated.

[0078] 图20显示了本发明的实施例是如何通过调整可控弯曲段5的硬度分布使设计形变更易实现,其中图20B、图20C为可控弯曲段5放大后的侧视图。 [0078] FIG. 20 shows an embodiment of the present invention is how to adjust the controlled distribution of bending stiffness section 5 makes the design easier to implement by deformation, wherein 20B, the FIG. 20C is a side view of the controlled deflection amplifying section 5. 图20中可控弯曲段5上的空白部分应理解为可控弯曲段5间隔一定距离的结构硬度降低,这种硬度下降不仅可以通过改变结构设计的方式实现也可以通过改变材料硬度的方式实现,因此可以通过调整可控弯曲段5上空白部分的大小、形态、分部密度等改变可控弯曲段5的硬度分布使其更易弯曲成为所需要的形态。 FIG blank portion 20 on the curved sections 5 controllable to be understood as a controlled bending stiffness structure at a distance from section 5 decreases, this decrease in hardness can be achieved not only by changing the structural design of the embodiment may be realized by changing the material hardness manner , it can be controlled by adjusting the size of a blank portion of the curved segment, shape, density changes in segment 5 controllable bending stiffness profile section 5 to make it easier bent into the desired shape. 与图19所示意的独立结构8的设计方案类似,可控弯曲段5也优选采用鸡肋样结构;当采用图17所示的鸡肋样结构时,可控弯曲段5可采用图17A和图17B所示的设计方案,其中图20B中虚线ccl所示的横截面的截面形态优选为图17B所示;当采用图18所示的鸡肋样结构时,图20A、图20B、图20C中可控弯曲段5的空白部分应理解为可控弯曲段5管壁间隔一定距离的结构硬度下降,例如通过去掉金属丝网、改变金属丝网的密度等;若需要弯曲的方向与图20B箭头aol所示的方向相反(即箭头ao2所示方向),则可采用图20C所示的设计方式。 Similar independent configuration 19 of FIG. 8 a schematic design, the curved section 5 is also preferably controlled tasteless like structures employed; when using chicken-like configuration shown in FIG. 17, the curved section 5 can be controlled. 17A and 17B FIGS. the design shown, in cross-section wherein FIG. 20B indicated by broken lines is preferably ccl section pattern as shown in FIG. 17B; when a chicken-like structure as shown in FIG. 18, FIG. 20A, FIG. 20B, FIG. 20C controllable 5 blank portion curved section curved to be understood as a controllable section 5 a distance from the wall spacer structural stiffness decreases, for example by removing a wire mesh, or the like to change the density of the metal mesh; if desired bending direction of the arrow in FIG. 20B as aol shown opposite direction (i.e. a direction indicated by arrow ao2) may be designed using the embodiment shown in FIG. 20C. 若需要可控弯曲段5向两侧都比较容易弯曲,可采用图20D所示的设计方案,即优选在可控弯曲段5相对的两侧分别设置图17或/和图18所示意的鸡肋样结构;当采用图17所示意的鸡肋样结构时,其设计方式类似图17C所示,只是各区域的大小稍有调整(如图20D中间图所示),由于可弯控曲段5两侧的整体硬度比较小,可控弯曲段5更容易向两侧弯曲;当采用图18所示意的鸡肋样结构吋,图20D中可控弯曲段5的空白部分应理解为可控弯曲段5管壁间隔一定距离的结构硬度下降,例如通过去掉金属丝网、改变金属丝网的密度等。 If desired controllable curved sections 5 are relatively easily bent toward both sides, the design shown in FIG. 2OD may be employed, i.e., is preferably provided, or the illustrated in FIG. 17 / FIG. 18 and 5 chicken in opposite sides respectively controlled curved segments like structure; when tasteless like structure illustrated in FIG. 17, which is designed in a manner similar to FIG. 17C, only a slight adjustment of the size of each region (intermediate 2OD shown in Figure), controlled bending since two curved segments 5 overall hardness of the side is relatively small, controlled bending section 5 is bent more easily to both sides; chicken-like structure as illustrated inch using FIG. 18, the blank portion of FIG. 2OD controlled deflection section 5 should be understood to controllably bend segment 5 a distance from the wall structure of the decrease in hardness, for example, by removing a metal mesh, a metal mesh or the like to change the density. 如图20D的左右两幅侧视图所示,两侧鸡肋样结构的排布不一定完全对称,可以有一定的错位。 As shown in FIG. 20D, two left and right side, chicken-like structure may not be entirely symmetrical arrangement on both sides, there may be some misalignment. 对于需要实现多向弯曲(大于等于3个方向),可空弯曲段5可采用图17所示意的鸡肋样结构的扩展设计方案和图18D所示的鸡肋样结构来帮助多向弯曲的实现。 The need to bend multi (three or more directions), chicken-like structure can be bent blank shown in section 5 can be expanded and the design illustrated in FIG. 17 tasteless like structure 18D to help achieve multi-directional bending. 此外对于技术人员需要可弯控曲段5形成其他弯曲形态的情況,可以对图20中可控弯曲段5的空白部分进行相应调整。 In addition to the skilled person needs to be controlled curved bending portion 5 is formed of other curved form, can be adjusted to the blank portion 20 in FIG. 5, controlled deflection section.

[0079] 此外,图19、图20、图21、图22、图23所示意的空白部分除了有助于消融导管I形成设计形变的作用外,还能够缓冲消融导管I对血管的压力,起到保护血管的作用。 [0079] Further, FIG 19, FIG 20, FIG 21, FIG 22, FIG 23 is a schematic blank portion I is formed in addition to contribute to an ablation catheter designed deformation effect, but also capable of buffering an ablation catheter to a pressure vessel I, from to protect the blood vessels.

[0080] 图24显示了本发明的实施例中导引导管7尾部的主要结构特点。 [0080] FIG. 24 shows the main structural features of the embodiments of the present invention, the tail guide catheter 7. 如图24A所示,根据实际需要,导引导管7的末端(尾端、近端)可设有开孔77,开孔77与一段导管20连接后与注射器或注液装置相连,因此可通过开孔77行血管内注药或注射血管内造影剤,开孔77不使用时导管20是封闭的。 24A, according to actual needs, the end (trailing end, a proximal end) 7 of the guide catheter may be provided with an opening 77, opening 77 is connected to the rear section of conduit 20 is connected to the syringe or the injection device, and therefore can injection openings 77 or angiographic injection Ji, opening 77 does not use endovascular catheter 20 is closed. 如图24所示,导引导管7的尾部最好有密封设计,例如密封圈或密封套79,防止血液经导引导管7漏出和防止经导引导管7向血管内注射的药物或注射的造影剤漏出,其中图24A、图24B显示的是没有插入消融导管I的情況,图24C显示的是插入消融导管I的情况,图24B、图24C为导引导管7尾部的放大图;如图24所示,此外导引导管7的尾部周围最好有加固套78,使导引导管7尾部不易形变,便于操作,同时也方便与其他结构进行连接或贴附在其他结构上。 24, the tail guide catheter 7 preferably have seals designed, for example, seals or glands 79, through the guiding catheter to prevent blood leakage and prevent 7 7 via the guide catheter into the blood vessel of a drug injection or injection Ji contrast leakage, wherein FIG. 24A, FIG. 24B shows the insertion of the ablation catheter is not I, and FIG. 24C shows the case where the insertion of the ablation catheter I, FIG. 24B, FIG. 24C is an enlarged view of the catheter introducer tail 7; FIG. Figure 24, furthermore preferably 7 around the tail guide catheter 78 has a reinforcing sleeve, the guide catheter tails 7 unlikely to be deformed, ease of operation, but also to facilitate the connection or attached to other structures and other structures. 导引导管7本身也可以在线控结构控制下发生形变,同时也可设置预制形变。 7 deformation guiding catheter itself can also occur online control structure of the control, while pre-deformation may be provided. 如图24A所示,对于导引导管7仅有预制形变的情况,优选不设置导引导管控制柄27,其末端可仅设置连接接头71,连接接头71可与注射器、注液装置、消融导管I等连接。 24A, in the case of the guide catheter 7 is only a pre-deformation, a guide catheter is preferably not provided a handle 27 which can be provided only connection joint end 71, 71 may be connected to, injection with syringe fitting means, ablation catheter I peer connection. 图25显示了本发明的实施例中导引导管7线控结构设计的主要结构特点以及如何通过调整导引导管7的硬度分布促进导引导管7形成所需要形变形态。 Figure 25 shows the main structural features of the embodiments of the present invention, a guide catheter wire 7 and how to design a hardness distribution conduit 7 7 facilitates guiding catheter to form the desired shape by adjusting the deformation of the guide. 在导引导管7的线控结构设中,优选以增加导向丝70张力(即牵拉导向丝70或前送导引导管7除导向丝70外的其他部分)的方式对导引导管7进行控制,当然技术人员也可以根据情况以增加导向丝70应力(即推送导向丝70或回退导引导管7除导向丝70外的其他部分)的方式对导引导管7进行控制。 The guide wire catheter structure 7 is provided, it is preferable to increase the tension in the wire 70 (i.e., pulling the guide wire feed other portions except for the guide wire 70. The guide catheter 70, or before 7) manner 7 guide catheter control, of course, also possible according to the situation in the art to increase the stress in the wire 70 (i.e., portions other push the wire 70 outside the guidewire 70 or guide catheter backoff 7) of the guide catheter 7 manner controlled. 如图25A所示,在导引导管7的一侧管壁中设有导向丝70,当增加导向丝70的张力时,导引导管7将向设置导向丝70的一侧发生弯曲,也即图中箭头aol所示方向,如果导引导管7需要实现多向控制弯曲可在导引导管7的几个方向上分别设置导向丝70。 25A, the guide wire 70 is provided in a side wall of the guide catheter 7, when increasing the tension in the guide wire 70, guide catheter 7 to be set to the side of the guide wire 70 is bent, i.e. aol direction of an arrow shown in the figure, if required guide catheter 7 to the control multi-curved guidewire 70 may be provided in several directions, respectively, the guide catheter 7. 为了方便导引导管7形成需要的形变形态,可以改变导引导管7小段的硬度分布,这种硬度分布的改变不仅可以通过改变结构设计的方式实现也可以通过改变材料硬度的方式实现;图25B、图25C是以改变导引导管7小段的结构设计为例进行说明的,图25B、图25C中导引导管7管壁的空白部分代表管壁结构硬度减低的部分,对于通过改变导引导管7小段的材料硬度的方式,只需要将图25B、图25C中导引导管7管壁的空白部分用较软的材料进行制造。 In order to facilitate deformation of the guide catheter 7 formed shape desired, the guide catheter may be varied hardness distribution subparagraph 7, the change of the hardness distribution can be achieved not only by changing the material hardness manner by changing the structural design of the embodiment; FIG. 25B FIG 25C is a guide catheter 7 to change the design of small pieces as an example, and 25B, the guide catheter in FIG. 25C wall 7 of the blank part represents the wall portion of reduced structural rigidity for the guide catheter by changing the embodiment 7 hardness of the material of the small pieces, simply 25B, the blank portion of the guide catheter of FIG. 25C wall 7 be manufactured with a relatively soft material. 如图25B、图25C所示,导引导管7可采用鸡肋样结构,并优选采用图32所示的鸡肋样结构的设计方案;如图25B所示,当需要加强导引导管7向箭头aol所示方向弯曲时,可将箭头aol侧的导引导管7管壁中加强管壁硬度的设计结构削弱,例如可间隔一定距离将箭头aol侧导引导管7管壁中的金属丝去掉,当增加导向丝70的张力时,导引导管7将更容易向箭头aol方向弯曲;如图25C所示,对于线控双向弯曲的情况,可将导引导管7两侧管壁中加强管壁硬度的设计结构削弱,例如,可间隔一定距离将箭头ao2和箭头ao3侧导引导管7管壁中的金属丝去掉;对于多向控制弯曲的鸡肋样结构可以参考图32D的设计方案。 FIG. 25B, FIG. 25C, the guide catheter can be tasteless like structures 7, and tasteless preferable design configuration like shown in FIG. 32; shown, the guide catheter when it is necessary to strengthen the arrow 7 in FIG. 25B aol as shown in the direction of bending, the guide catheter can arrow aol side wall 7 designed to strengthen the structure of the weakened wall of hardness, for example, at a distance from the wire arrow aol side wall 7 of the guide catheter is removed, when 70 increases the tension of the wire, the guide catheter will easily bend 7 in the arrow direction aol; FIG. 25C, for bidirectional bending of the wire, the guide catheter may be 7 in both sides of the wall reinforcing wall hardness design structurally weakened, for example, at a distance from the wire and arrows arrows ao2 ao3 side wall 7 of the guide catheter removed; for multidirectional controlling chicken-like bent design can refer to FIG. 32D. 另外,导引导管7头部也可以先制成向某个方向的弯曲形态,这样在导引导管7不具有线控结构控制形变时,也可帮助导引导管7到达肾动脉,若在导引导管7具有线控结构控制其形变时,导引导管7的预制弯曲状态还能够增加导引导管7的控制弯曲方向,例如将导引导管7的线控结构控制形变的弯曲方向设置成与预置形变弯曲方向相反,这样就可以控制两个方向的弯曲。 Further, the guide catheter head 7 may also be made of curved shape to a certain direction, so that the guide wire catheter structure 7 does not have a control deformation may also help guide catheter 7 reaches the renal arteries, if the guide wire guide tube 7 having a structure which deformation control, pre-curved guide catheter is also possible to increase the state 7 to control the bending direction of the guide duct 7, for example, the bending direction of guide wire structure of the duct 7 is arranged to control the deformation and preset direction opposite to the bending deformation, so that the bending can be controlled in two directions. 导向丝70在导引导管7管壁中的走行路径根据导引导管7的形变形态而定,一般与导引导管7长轴中性线平行;导向丝70可连接到导引导管7尾端独立的导引导管控制柄27上,该导引导管控制柄27可以与控制手柄2相连接或独立存在,导引导管7内的导向丝70也可以直接连接到控制手柄2,由控制手柄2控制(后述)。 The guide wire 70 traveling in the guide catheter wall 7 forms a path according to the deformation of the guide duct 7, are generally parallel to the long axis of the neutral line 7 of the guiding catheter; guide wire 70 may be connected to the trailing end of the guide catheter 7 separate guide catheter handle 27, the guide catheter 27 can handle 2 connected to the control handle or independent of the presence of the guide wire within the guide catheter 770 may also be connected directly to the control handle 2, a control handle 2 control (described later). 对于导引导管7的磁控结构设计,优选将永磁体、电磁铁或其他能够被磁铁吸引的物质设置在导引导管7头部及其附近位置的管壁中,通过外加磁场方向的改变能够控制导引导管7多个方向的弯曲。 For the head 7 and the guide catheter wall near the location can be changed by applying a magnetic field direction of the structural design of the guide duct 7, preferably permanent magnets, electromagnets, or other material capable of being attracted by a magnet provided controlling the plurality of curved guide catheter 7 directions. 对于采用磁控结构设计的导引导管7也可以通过调整导引导管7的结构设计和导引导管7小段的制造材料的硬度进而改变导引导管7的硬度分布使设计的形变更易实现。 For the design of the magnetron guide catheter 7 to be further changed by adjusting a guide catheter guide catheter and guide catheter design hardness 7 7 for producing small pieces of material hardness distribution 7 makes design easier to implement deformation. 当然技术人员可以根据实际需要,调整永磁体、电磁铁或其他能够被磁铁吸引的物质在导引导管7上的设置位置,使导引导管7形成其他形状的形变。 Of course, according to actual needs in the art can adjust the set position of a permanent magnet, an electromagnet, or other material capable of being attracted by a magnet on the guide conduit 7, the guide duct 7 is formed in another shape deformation.

[0081] 所述的消融导管I和导引导管7外表面可以标记显影刻度,以指示消融导管I和导引导管7进入血管的深度以及方便在超声、X射线等影像设备下间接测量人体结构的长度、宽度等。 [0081] The outer surface of the ablation catheter 7 and the guide catheter may be marked I developed a scale to indicate the ablation catheter I and guiding catheter into a blood vessel 7 and to facilitate an indirect measurement of the depth of the anatomy under ultrasound, X-rays and other imaging equipment the length, width and the like. 消融导管I和导引导管7上还可设置不同的显影标记用于在超声、X射线等影像设备下区分不同的导管。 Ablation catheter I and guiding catheter may also be provided for different development marker under ultrasound, X-rays and other imaging devices to distinguish different conduit 7. 各独立结构8上优选设置不同的显影标记用于在超声、X射线等影像设备下区分不同的独立结构8,例如在一条独立结构8上标三角形,而另一条独立结构8标正方形,或在一条独立结构8上标三条带,而另一条独立结构8标两条带。 Different structures 8 each independently preferably provided on the developing markers for ultrasound, X-rays and other imaging devices to distinguish different independent structure 8, for example, a separate structure 8 superscript triangle, and the other independent standard square configuration 8, or 8 are denoted on a separate three bands, and the other with two independent structures 8 standard. 此外消融导管I和导引导管7上还可设置显影标记用于在超声、X射线等影像设备下区分不同的轴向旋转状态,例如在消融导管I的左侧面设置一条在超声、X射线等影像设备下能够显影的短线,在消融导管I的右侧面设置另一条在超声、X射线等影像设备下能够显影的短线,当消融导管I处于水平位置时两条短线重合,当消融导管I轴向旋转一定角度时,短线则分开一定距离。 Further ablation catheter I and guiding catheter may also be provided for the X-ray opaque marker under ultrasound, X-ray and other imaging devices to distinguish different axial rotation state, for example, is provided in a left side surface of the ultrasonic ablation catheter I, 7 etc. can be developed at short imaging device provided in the right side surface of the other I ablation catheter under ultrasound, X-rays and other imaging devices can be developed short-term, when the ablation catheter in the horizontal position I coinciding two short, when the ablation catheter when I axial rotation angle, the short distance apart. 为了降低消融导管I和导引导管7对血管造成损伤的可能性,优选地,消融导管I和导引导管7与血管壁接触的地方最好尽量光滑,同时形态最好尽量的圆滑,此外消融导管I和导引导管7的头部最好比较软。 To reduce the possibility of the ablation catheter I and guiding catheter 7 vascular damage, preferably, local ablation catheter I and guiding catheter into contact with the vessel wall 7 is preferably as smooth as possible, while the best possible form of smooth, in addition ablation I catheters and guide catheter head 7 is preferably relatively soft.

[0082] 消融导管I和导引导管7中可能直接或间接与人体体液或组织接触的部分都必须达到相应的与人体体液或组织接触材料的国家标准,对于不能达到上述要求又可能直接或间接与人体体液或组织接触的消融导管I和导引导管7的部分,其外面必须用符合与人体体液或组织相接触材料的国家标准的材料包裏。 [0082] The ablation catheter I and guiding catheter portion may be directly or indirectly in contact with body fluids or tissues must meet the corresponding 7 national standard material in contact with body fluids or tissues, to achieve the above requirements and can be directly or indirectly and contacting bodily fluids or tissue ablation catheter I and guiding catheter portion 7, its outer bag material must conform in contact with bodily fluids or tissue material of national standards. 消融导管I和导引导管7可能与人体直接或间接接触部分的制造材料应能够耐受至少ー种医用消毒方法。 Ablation catheter I and guiding catheter with the body 7 may be directly or indirectly producing contact portion material should be capable of withstanding at least ー kinds of medical sterilization methods. 消融导管I和导引导管7可能与人体直接或间接接触的部分应该是绝缘的,对于不能达到绝缘要求的地方可以外包裹绝缘材料。 Ablation catheter and guiding catheter I and part of the body 7 may be direct or indirect contact shall be insulated, insulation requirements can not be achieved to place the overwrap may be an insulating material.

[0083] 上述可控弯曲段5的作用在导管体段4不设置可控弯曲段5时,可以由导管体段4代为行使,只需要将上述可控弯曲段5的设计方案运用于导管体段4即可。 [0083] The effect of controlled deflection section 5 in the catheter body section 4 is not provided controllably bent section 5, the catheter body may be made on behalf of the exercise section 4, the curved section just to the above-described controllable design applied to the catheter body 5 section 4 can be.

[0084] 技术人员可以根据实际要求对上述这些消融导管I和导引导管7的设计方案进行融合、改进以及交叉使用,这些等效变化和修饰同样落入本发明的实施例权利要求所限定的范围。 [0084] the art can be based on the actual requirements of the above-described design of the ablation catheter 7 and the guiding catheter I fusion, modifications and cross-use, such equivalent variations and modifications are also within the claims of the present embodiment of the invention as defined range.

[0085] 对于导引导管7连接于控制手柄2由控制手柄2负责控制的情况,控制手柄2可以同时控制导引导管7和消融导管I。 [0085] In the case of a guide catheter 7 is connected to the control handle 22 is responsible for controlling the control handle, the control handle 2 can control the ablation catheter and the guide catheter 7 I. 根据导引导管7可以被控制的弯曲方向数量和可以被控制的弯曲方式,控制手柄2的设计略有不同。 The number of the bending direction of guide catheter 7 can be controlled manner and bending can be controlled, the control handle 2 is slightly different design. 由于一般采用线控结构对导引导管7的形变进行控制,因此控制手柄2的设计是以线控结构为基础的,对于导引导管7形变的其他控制方式,只需要在线控结构控制手柄2的基础上稍加改进。 As the general structure of the handle of the guiding catheter 2 wire 7 is controlled deformation, the control handle design is based on a 2-wire configuration, the guide catheter to the other control mode deformation 7, only the control line control structure slightly modified basis. 图26、图27、图28均是以线控结构为例,显示了控制手柄2的主要结构特点。 FIG 26, FIG 27, FIG 28 is a wire structure are an example, shows the main structural features of the control handle 2. 图26A、图26C、图27所示意的设计方案中,导引导管7与控制手柄2稳定相连,由控制手柄2负责控制;图26B所示意的设计方案中,导引导管7通过末端的连接接头71与消融导管I尾部连接,需要的时候,导引导管7又能够与消融导管I末端分离;图28所示意的设计方案中,导引导管7与导引导管控制柄27相连,由导引导管控制柄27负责控制。 FIG. 26A, FIG. 26C, the design illustrated in FIG. 27, the guide pipe 7 is connected with a control handle 2 stable, responsible for controlling the control handle 2; FIG. 26B is a schematic design of the guide pipe 7 by connecting the end of the I tail joint 71 connected to the ablation catheter, when required, the guide catheter and 7 can be separated from the ablation catheter tip I; the design illustrated in FIG. 28, the guide catheter and guide catheter 7 is connected to the control handle 27, by the guide guide tube handle 27 is responsible for controlling. 图26、图27、图28中虚线ac代表控制手柄2内的导线、细导管、光纤。 FIG 26, FIG 27, FIG 28 the broken line representing the control handle in the ac leads 2, thin catheter, an optical fiber.

[0086] 图26显示了本发明的实施例中不能通过线控结构控制导引导管7弯曲方向的情况下,控制手柄2的主要结构特点。 [0086] FIG. 26 shows the case of the embodiment of the present invention can not be controlled by the configuration guide catheter wire bending direction 7, the control handle 2 of the main structural features. 图26A、图26C显示了导引导管7与控制手柄2稳定相连情况下,控制手柄2的主要结构特点,图26B显示了导引导管7通过末端的连接接头71与消融导管I尾部连接的情况下,控制手柄2的主要结构特点,其中图26C为图26A中虚线cc横截面放大的截面示意图。 FIG. 26A, FIG. 26C shows a guiding catheter with a control handle 7 is connected to the case 2 stably, the main structural features of the control handle 2, and FIG. 26B shows a case where the guiding catheter ablation catheter 7 through the connecting joint connecting the tail I ends 71 , the main structural features of the control handle 2, wherein the dashed line in FIG. 26C is a schematic cross section of an enlarged cross-sectional cc FIG 26A. 如图26A所示,控制手柄2优选设计成图示形状,主要由操 26A, the control handle 2 is preferably designed as illustrated in shape, primarily by the operator

23作柄271和操作柄226组成,其中操作柄271 —般位于控制手柄2的前部,主要负责控制导引导管7,而操作柄226 —般位于控制手柄2的后部,主要负责控制消融导管I ;操作柄271与导引导管7末端相连,操作柄271和操作柄226通过图中虚线矩形框ar标示的槽齿滑动结构进行连接,槽齿滑动结构由操作柄271尾部的环形钩状结构272和操作柄226头部的环形钩状结构240相互吻合组成,且连接后能够进行相对转动。 23 for the handle 271 and the handle 226, where the handle 271 - as the front portion of the control handle 2, is mainly responsible for controlling the guide catheter 7, and the handle 226 - as located in rear of the control handle 2, is mainly responsible for controlling the ablation catheter I; 7 handle 271 is connected to the tip of the guide catheter, the handle 271 and the handle 226 are connected by a sliding tooth groove dotted rectangular frame structure indicated in FIG ar, sliding tooth structure by an annular groove 271 end of the handle hook structures annular hook structure 272 and the handle 226 of the head 240 coincide with each other composition, and is capable of relative rotation connection. 如图26A、图26C所示,消融导管I与横截面成辐射状展开的连接杆251相连,连接杆251与环形控制钮250相连,推送(如图26B示)或回退环形控制钮250即可实现消融导管I的前进或回退,由于控制钮250成环状,因此即使旋转操作柄226仍不影响通过环形控制钮250控制消融导管I。 FIG. 26A, FIG. 26C, the cross section of the ablation catheter I expanded radially into a connecting rod 251 is connected to the connecting rod 250 is connected to an annular control knob 251, a push (shown in FIG. 26B) or rolled back annular control knob 250 i.e. advancing the ablation catheter can be achieved or backoff I, since the control knob 250 in a ring, so even if the annular control knob 226 does not reduce the rotational operation lever 250 by controlling the ablation catheter I. 图26C显示了图26A虚线cc横截面放大的截面示意图,有助于进一步说明连接杆251、环形控制钮250、操作柄226的空间结构关系。 FIG. 26A FIG. 26C show a cross-sectional schematic enlarged cross-section a broken line cc, help to further illustrate the connecting rod 251, an annular control knob 250, the handle 226 of the spatial structural relationships. 如图26C所示,消融导管I与横截面成辐射状展开的连接杆251相连,连接杆251穿过操作柄226上的一段开槽244与环形控制钮250,由于开槽244能限制连接杆251的转动,因此转动环形控制钮250和操作柄226的任意一个都能实现两者一起转动,进而实现消融导管I的转动;当然开槽244的长度即为消融导管I能够移动的距离,该长度一般小于环形控制钮250的宽度,这样环形控制钮250能够覆盖开槽244,环形控制钮250滑动时也不至于显露控制手柄2的内部结构;连接杆251和开槽244的数量不一定为四个,可以根据实际需要进行调整。 As shown in FIG. 26C, the cross-section I ablation catheter to expand radially into the connecting rod 251 is connected to the connecting rod 251 passes through slot 244 and annular section of the control knob 250 operating handle 226, since the slot 244 to limit the connecting rod 251 is rotated, thus controlling rotation of the annular any button 250 and a handle 226 can be realized both rotate together, so as to realize an ablation catheter is rotated I; of course is the length of the slot 244 of the ablation catheter I can move from the a length generally less than the width of the annular control knob 250, so that an annular control knob 250 to cover the slot 244, when the control button 250 sliding ring structure that does not expose the internal control handle 2; connecting rod 251 and slot number 244 are not necessarily as four, it can be adjusted according to actual needs. 如图26A所示,在操作柄226的尾部优选设有能量交换接头201,能量交换接头201通过缆线23 (内含导线、光纤或细导管等,图I示)与消融发生装置部分3相连,主要负责接收由消融发生装置3传来的能量并将该能量通过控制手柄2内的导线、细导管、光纤ac等传输至消融头9、消融导管I上其他需要能量供应的部分、导引导管7上需要能量供应的部分及控制手柄2上需要能量供应的部分,同时能量交换接头201还兼具有传递消融导管I、导引导管7和控制手柄2上的传感器信号以及接收消融发生装置3传来的指令并将其传给消融导管I、导引导管7和控制手柄2的作用。 26A, the lever 226 is preferably provided with energy exchange tail joint 201, the joint 201 energy exchange through a cable 23 (containing wires, or fine fibers such as a catheter, shown in FIG. I) with the ablation generator portion 3 is connected , mainly responsible for receiving the ablation energy by the generator 3 and the energy transmitted by the control wire handle, thin catheter, optical fiber transmission in the other ac 2 to the ablation head 9, the ablation energy supply other needs conduit portion I, the guide It requires energy supply catheter section 7 and a control handle portion of the required energy supply 2, while the energy exchange joint 201 and further transmitted ablation catheter having I, 2 on the sensor signal and the control handle 7 guide catheter ablation generating means and receiving 3 and instructions coming from the ablation catheter to pass I, the role of the guiding catheter and a control handle 7 2. 如图26A所示,操作柄226的末端与能量交换接头201邻近的位置根据情况可设置液体灌注接头202,液体灌注接头202与消融导管I内的细导管相连,用于向消融导管I提供冷却液、造影剂等,液体灌注接头202在控制手柄2外通过导管与液体灌注器203相连,该液体灌注器203可以设置在消融发生装置部分3上,受消融发生装置部分3的控制,也可以是独立于消融发生装置部分3的系统,同时该液体灌注器203可以是手动进行液体灌注,也可以是自动进行液体灌注。 26A, the position of the operating handle 226 and an end fitting 201 adjacent the energy exchange as the case may be provided a liquid infusion fitting 202, fitting 202 is connected to the liquid infusion catheter ablation catheter fine I for the ablation catheter to provide cooling to the I liquid contrast agent, a liquid filling joints 202,203 in the control handle 2 is connected to the outer conduit by perfusion liquid, a perfusion liquid 203 may be provided in the ablation portion 3 generating means, generating means controlled by the ablation section 3, may be generating system is independent of the ablation device portion 3, while the perfusion fluid 203 may be manually filling a liquid, the liquid may be automatically reperfusion. 此外在操作柄226的外表面和环形控制钮250的外表面可标示消融导管I推送距离及推送方向,在环形钩状结构272的外表面和操作柄226的外表面可标示操作柄271和操作柄226相对旋转角度及旋转方向。 Further, in the outer surface of the handle 226 and the annular outer surface of the control knob 250 may indicate a distance and push the ablation catheter to push the direction I, the outer surface of the annular outer surface 272 of the hook structure and the operating handle 226 and 271 may indicate the operating handle handle 226 relative rotation angle and the rotation direction. 如图26B所示,整个控制手柄2主要由操作柄217组成,导引导管7将不与控制手柄2相连,消融导管I末端将与操作柄217的头端相连,在消融导管I的近端设有加固套48,以使消融导管I与控制手柄2连接的地方不易形变,便于操作。 As shown in FIG 26B, the entire operation of the control handle 2 is mainly composed of handle 217, the guide catheter is not connected to the control handle 2 and 7, the ablation catheter tip I handle connected to the head end 217, the proximal end of the ablation catheter of I reinforcement sleeve 48 is provided, so that the local ablation catheter is connected to the control handle 2 I unlikely to be deformed, easy to operate. 如图26B所示,导引导管7通过末端的连接接头71与消融导管I尾部相连,消融导管I尾部的加固套48有助于消融导管I与连接接头71相连,导引导管7内的密封圈或密封套79能够防止血液经导引导管7漏出和防止经导引导管7向血管内注射的药物或注射的造影剂漏出;对消融导管I的控制将主要通过前送或回退操作柄217以及旋转操作柄217。 As shown in FIG. 26B, the guide catheter 771 and an ablation catheter is connected to I tail, the reinforcing sleeve ablation catheter tails 48 I I help ablation catheter is connected with the connection joint 71, the sealing in the connection joint 7 by the end of the guide catheter ring or sleeve 79 can be sealed to prevent blood leakage through the guiding catheter 7 through the guiding catheter and prevent leaking 7 of intravascular injection or injection of a contrast agent medicament; I is controlled ablation catheter primarily by sending the front or back operation lever 217 and rotating handle 217. 如图26B所示,类似地,在操作柄217的尾部优选设有能量交换接头201,根据情况能量交换接头201的旁边可设置液体灌注接头202。 As shown in FIG. 26B, similarly, the operation lever 217 in the tail portion 201 is preferably provided with joint energy exchange, the exchange joint 201 may be provided next to the liquid infusion energy joint 202 according to the situation.

[0087] 图27显示了本发明的实施例中能够通过线控结构控制导引导管7弯曲方向的控制手柄2的主要结构特点;其中图27A、图27B显示了控制手柄2能够控制导引导管7向一个方向弯曲情况下控制手柄2的主要结构特点,图27C、图27D显示了控制手柄2能够控制导引导管7向两个方向弯曲情况下控制手柄2的主要结构特点,图27E、图27F是以四根导向丝70的情况为例,显示了控制手柄2能够控制导引导管7向多个方向3方向)弯曲情况下控制手柄2的主要结构特点;由于图27中操作柄226的设计方案与图26A、图26C中操作柄226的设计方案相同,因此图27主要显示了操作柄271的结构特点,此外对于图27所示意的控制手柄2的设计方案与图26所示意的控制手柄2的设计方案相同的地方这里就不再复述。 [0087] FIG. 27 shows a control handle embodiment of the present invention can be controlled catheter guide wire structure 7 by main structural features of the bending direction 2; Figure 27A, FIG. 27B shows a control handle capable of controlling the guiding catheter 2 the main structural features of the control handle 2 is bent in one direction 7 of the case, FIG. 27C, FIG. 27D shows the control handle 2 is capable of controlling guide catheter control handle 2 of the main structural features of the two directions 7 the case is bent, FIG. 27E, FIG. 27F is a case where the guide wire 70 four example, the control handle 2 shows the guide catheter is capable of controlling the control handle 7 2 main structural features of the plurality of directions 3) is bent in the case; FIG. 27 because of the operation lever 226 design and FIG. 26A, FIG. 26C same as in the handle design 226, and therefore FIG 27 mainly shows the structural features of the handle 271, in addition to the control design 2 and 26 illustrated in FIG respect to FIG. 27 of the control handle illustrated the same design of handle 2 where there is no longer repeated. 图27A、图27B显示了控制手柄2能够控制导引导管7向ー个方向弯曲情况下,控制手柄2的主要结构特点,此时优选设置一根导向丝70 ;其中图27B为图27A中虚线ccl横截面放大的截面示意图。 FIG. 27A, FIG. 27B shows a control handle capable of controlling the guiding catheter 2 7 bent ー directions case, the main structural features of the control handle 2, in which case preferably provided a guide wire 70; Figure 27B is a broken line in FIG. 27A ccl enlarged cross-sectional schematic view of the cross section. 如图27A所示,导向丝70从导引导管7末端走行出后,经过操作柄271上的连接通道277与环绕操作柄271上类似环形的控制钮237相连,控制钮237可在操作柄271上滑动;当向箭头aol方向推送控制钮237吋,导向丝70将受到牵拉,通过这种方式能够控制导引导管7的弯曲方向。 Shown in Figure 27A, the guide wire 70 traveling from the tip of the guide conduit 7, through the connecting passage 271 on the handle 277 surrounds the ring-like handle 271 is connected to the control knob 237, control knob 271 on the handle 237 may be the slide; 237 inches when the push button control, the guidewire 70 is pulled through the guide catheter can be controlled in this way the bending direction of the arrow 7 direction aol. 为了避免导向丝70受到过分牵拉导致导引导管7的弯曲伤及血管壁,可设置缓冲结构,即将走行在连接通道277内的导向丝70的中间一段用弹簧或具有弾力的细线代替,图27A是以设置弹簧282为例进行说明的,在弹簧282处的连接通道277直径稍粗以容纳弹簧282,当牵拉导向丝70时,弹簧282可以伸展,这样能够起到缓冲牵拉カ的作用,同时由于弹簧282的直径略大于两边连接通道277的直径,因此弹簧282的伸展距离不会超过连接通道277膨大的部分,这就使得弹簧282到导引导管7头端的导向丝70的张カ不至于超过弹簧282最大伸展距离下所产生的拉力,也就相当于设定了一个拉カ限值。 To avoid over-stretch the wire 70 by the curved guide catheter 7 leads to injuries of the vessel wall, the buffer structure may be provided, coming down in the middle section of the wire line connection channel 27770 having a thin wire or spring force instead of Dan, FIG 27A is provided as an example of the spring 282, the spring 282 connected to the channel 277 to accommodate the thicker the diameter of the spring 282, when the guidewire 70 is pulled, the spring 282 can be extended, this can pulled cushion ka effect, due to the spring 282 while the connector diameter slightly greater than the diameter of the channel 277 on both sides, so the spring 282 extends from the connecting channels does not exceed the enlarged portion 277, which makes the guide wire 282 to the spring end of the guide catheter 70 7 Zhang grades will not exceed the maximum tension spring 282 extends from arising, it is equivalent to a set of pull-ka value. 当然为了避免导向丝70受到过分牵拉导致导引导管7的弯曲伤及血管壁,还可以在导向丝70上连接张カ传感器。 Of course, in order to avoid over-stretch the wire 70 by the curved guide catheter 7 leads to injuries of the vessel wall, may also be connected to the sensor sheet grades on the wire 70. 此外,技术人员还可以根据实际需要通过调节导向丝70的初始张力、导向丝70在控制手柄2内的走行路径、连接通道277在操作柄271凹陷部分的开ロ大小等方式调控控制钮237控制导向丝70的敏感性。 Furthermore, the skilled artisan can also be based on actual need by adjusting the guide wire initial tension 70, the guide wire 70 in the traveling path within the second control handle, the connecting passage 277 in the regulation opening ro size 271 recessed portion operating handle mode control knob 237 controls the sensitivity of the wire 70. 为了通过控制钮237的转动控制操作柄271的转动,可在控制钮237与操作柄271间设置槽齿滑动结构;如图27B所示,虚线小矩形框rc即为槽齿滑动结构所在的位置,虚线大矩形框内的图像显示了槽齿滑动结构的放大图,槽齿滑动结构由凹槽285和突出齿286组成,图27B是以凹槽285和突出齿286分别设置于控制钮237和操作柄271上为例进行说明的,根据具体情况也可将凹槽285和突出齿286分别设置于操作柄271和控制钮237上;当旋转控制钮237吋,由于槽齿滑动结构的存在,将带动操作柄271—起转动,同时控制钮237前后滑动又不会受到影响;技术人员可以根据需要调整槽齿滑动结构的位置以及设置数量,只要保证控制钮237和操作柄271能一起转动且控制钮237的前后滑动不受影响。 By rotation of the control knob 237 to the rotating control handle 271, knob 237 may control the handle 271 and teeth sliding groove structure is provided; the position shown in Figure 27B, a broken line is the small rectangular frame rc teeth sliding groove structure where large dashed line rectangle image shows an enlarged view of the teeth of the sliding groove structure, the structure of the teeth sliding groove by the groove 285 and the protruding teeth 286 composed of FIG. 27B is projecting teeth 286 and grooves 285 are provided in the control knob 237 and the operation lever 271 is described as an example, as the case may be projecting teeth 286 and grooves 285 are provided on the operating handle 271 and controls 237; 237 inches when the rotary control knob, the teeth due to the slide groove structure, since the handle will drive 271- rotate while sliding the control knob 237 back and forth and will not be affected; art may need to adjust the position and the number of teeth disposed sliding groove structure, as long as the control knob 237 and the handle 271 can rotate together, and control knob 237 to slide back and forth is not affected. 为方便操作,在操作柄271和控制钮237的外表面可标示控制钮237移动距离以及移动方向,在操作柄226的外表面、环形钩状结构272的外表面和控制钮237的外表面可标不操作柄271和操作柄226相对旋转角度及转动方向。 To facilitate operation, the outer surface of the control knob 271 and the handle 237 may indicate a movement distance and a movement direction 237 controls, may be, an outer surface and an outer surface of the control knob 237 of annular structure 272 of the hook outer surface of the operation lever 226 the handle 226 is not standard relative rotation angle and direction of rotation and the handle 271. 图27C、图27D显示了控制手柄2能够控制导引导管7向两个方向弯曲情况下,控制手柄2的主要结构特点,其中图27D为图27C中虚线cc2横截面放大的截面示意图。 FIG 27C, FIG. 27D shows the control handle 2 is capable of controlling guide catheter 7 is bent in two directions in the case, the main structural features of the control handle 2, is an enlarged schematic sectional view of a dotted line in FIG. 27C cc2 wherein the cross section of FIG 27D. 如图27C所示,此时优选设置两根导向丝70a、70b,两根导向丝70a、70b将各控制导引导管7 —个方向的弯曲,且分别经过连接通道277a、277b优选在相対的位置上与控制钮237相连,同样地也可设置弹簧282用于缓冲控制钮237对导向丝70的牵拉;控制钮237能够前后滑动,当控制钮237向箭头ao2方向滑动时,导向丝70b将受到牵拉,弹簧282b拉伸,而导向丝70a由于连接通道277a远端漏斗样槽278a的存在,其处于放松状态;当控制钮237向箭头ao3方向滑动时,导向丝70a将受到牵拉,弹簧282a拉伸,而导向丝70b由于连接通道277b远端漏斗样槽278b的存在,其处于放松状态。 Shown in Figure 27C, this time preferably provided two guide wires 70a, 70b, two guide wires 70a, 70b each control guide catheter 7-- bending directions, and each through 277a, 277b is preferably connected to the passage Dui phase is connected to a position control knob 237, in the same manner it can also be provided for pulling the spring 282 controls the buffer 237 of guide wire 70; and a control knob 237 can be slid back and forth, when the control knob 237 to slide ao2 direction of an arrow, the guide wire 70b will be pulled, stretching the spring 282b, and the guide wire 70a due to the presence of the distal end of the connecting channels 277a funnel-like grooves 278a, which in a relaxed state; when the button is slid ao3 direction of arrow 237, the guide wire 70a is pulled , a tensile spring 282a, and the guide wire 277b connecting channel 70b due to the presence of the distal end of the funnel-like groove 278b, which is in a relaxed state. 类似地,技术人员可以根据实际需要通过调节导向丝70的初始张力、导向丝70在控制手柄2内的走行路径、控制钮237突入操作柄271部分的位置、漏斗样槽278开口大小与设置位置等方式调控控制钮237控制两条导向丝70的敏感性,使得控制钮237在不同方向上离开初始位置相同距离的情况下两条导向丝70受到相同或不同大小力的牵拉。 Similarly, the skilled person according to actual needs by adjusting the guide wire initial tension 70, the guide wire 70 in the control handle traveling in the two paths, control the position of the button 237 protrudes handle 271 portion of the funnel-like groove 278 opening size of the installation position etc. case sensitivity control knob 237 controls the regulation of two guide wires 70, so that the control knob 237 the same distance away from an initial position in two different directions by the guide wire 70 the same or different amount of force pulling. 同样地,为了实现通过控制钮237的转动控制操作柄271的转动,图27C、图27D所示的设计方案也可采用图27B所示意的在控制钮237与操作柄271间设置槽齿滑动结构。 Likewise, in order to achieve 271 is rotated by controlling the rotation of the handle control knob 237, FIG. 27C, the design shown in FIG 27B may be employed in the illustrated control knob 237 and the handle 271 slidably tooth groove structure is provided in FIG. 27D . 若导引导管7有一个方向的预制弯曲形变,而导向丝70设置在另外一个方向以拮抗预制弯曲形变从而实现控制导引导管7两个相对方向的弯曲,在这种情况下需要从导向丝70a、70b中去掉一根,并去除相应的附属结构。 If a guide catheter 7 prefabricated bending deformation direction, and the guide wire 70 disposed in a direction to further antagonize the preform thus control the bending deformation of the guiding catheter curved 7 two opposite directions, it is necessary from the guide wire in this case 70a, 70b are removed one, and the removal of the corresponding secondary structure. 同样地,在操作柄271和控制钮237的外表面可标示控制钮237移动距离以及移动方向,在操作柄226的外表面、环形钩状结构272的外表面和控制钮237的外表面可标示操作柄271和操作柄226相对旋转角度及转动方向。 Similarly, the outer surface of the control knob 271 and the handle 237 may indicate a movement distance and a movement direction 237 controls, in the outer surface of the handle 226, an outer surface and an outer surface of the control knob 237 of annular structure 272 may indicate the hook the handle 271 and the handle 226 relative to the rotational angle and rotational direction. 图27E、图27F是以四根导向丝70的情况为例,显示了控制手柄2能够控制导引导管7向多个方向O 3方向)弯曲情况下控制手柄2的主要结构特点,其中图27F为图27E中虚线cc3横截面放大的截面示意图。 FIG. 27E, FIG. 27F is a case where the guide wire 70 four example, the control handle 2 shows the guide catheter is capable of controlling a plurality of directions to a third direction 7 O) at bending main structural characteristics of the control handle 2, wherein FIG. 27F the broken line in FIG. 27E is a schematic cross-sectional enlarged sectional cc3. 如图27E所示,图27A、图27B、图27C、图27D中控制导向丝70的控制钮237由控制盘238代替,控制盘238没有突入操作柄271的部分,且操作柄271与控制盘238之间的接触面是球形万向关节的一部分,因此控制盘238能够向多个方向转动,且向前或向后推动控制盘238不会使其移动而滑出操作柄271。 As shown in FIG. 27E, FIG. 27A, 27B, and 27C, FIG. 27D controls the control knob 70 of the guide wire 237 is replaced by a control panel 238, control panel 238 is not part of the handle 271 protrudes, and the operating lever 271 and the control panel the contact surface between the ball joint 238 is a joint part, the control disc 238 can be rotated in a plurality of directions, and pushing forward or backward movement of the control panel 238 will not slip out so that the handle 271. 由于截面的原因图27E仅显示了两条导向丝70a、70c。 Due to FIG. 27E shows only a section of the two guide wires 70a, 70c. 如图27E、图27F所示,各控制可控弯曲段5—个方向弯曲的四根导向丝70a、70b、70c、70d将分别经过连接通道277a、277b、277c、277d与控制盘238相连,四根导向丝70优选地均匀分布于控制盘238和操作柄271的圆周上,同样地也可设置缓冲结构,例如设置弹簧282用于缓冲控制盘238对导向丝70的牵拉;当控制盘238向箭头ao4所示方向转动时,导向丝70c将受到牵拉,弹簧282c拉伸,而导向丝70b由于连接通道277b远端漏斗样槽278b的存在,其处于放松状态;当控制盘238向箭头ao5所示方向转动时,导向丝70a将受到牵拉,弹簧282a拉伸,而导向丝70c由于连接通道277c远端漏斗样槽278c的存在,其处于放松状态;如果控制盘238转动方向不在任何一条导向丝70上,此时将有两条相邻的导向丝70受到牵拉,这样导引导管7将向两条受到牵拉的导向丝70合力的方向弯曲,通过这样的方式即实现了控 FIG. 27E, FIG. 27F, each of the curved segments 5- controllable in four directions bending the wire 70a, 70b, 70c, 70d are connected respectively through passages 277a, 277b, 277c, 277d is connected to the control panel 238, four guide wire 70 is preferably uniformly distributed in the control panel 238 and the handle 271 on the circumference, in the same manner may be provided a buffer structure, for example a spring 282 for pulling buffer control disk 238 of guide wire 70; and when the control disk when 238 is rotated in the direction indicated by arrow ao4, guide wire 70c will be pulled, stretching the spring 282c and the guide wire 277b connecting channel 70b due to the distal end of the funnel-like groove 278b, which is in a relaxed state; when the control panel 238 to ao5 rotated in the direction shown by arrow, the guide wire 70a is pulled, the tensile spring 282a, and the guide wire 70c connecting channel 277c due to the distal end of the funnel-like grooves 278c, which is in a relaxed state; if the control direction of the disk 238 is not rotated any one guide wire 70, then there will be two adjacent guidewire 70 is pulled, so that the direction of the guide conduit 7 will be two guidewire 70 is pulled in the bending force, i.e. realized in such a way the control 导引导管7的多向弯曲。 Multi-curved guide catheter to 7. 类似地,技术人员还可以根据实际需要通过调节导向丝70的初始张力、导向丝70在控制手柄2内的走行路径、漏斗样槽278开口大小与设置位置等方式调控控制盘238控制四条导向丝70的敏感性,使得控制盘238在四条导向丝70方向上离开初始位置相同距离的情况下四条导向丝70受到相同或不同大小力的牵拉。 Similarly, in the art it can also be based on actual need by adjusting the guide wire initial tension 70, the guide wire 70 in the control handle traveling path in 2, a funnel-like groove 278 opening size of the installation position, etc. regulatory control panel 238 controls four guidewire 70 the sensitivity of the control panel 238 such that the same distance away from the initial position of the guide 70 in the four directions case four wire guidewire 70 being the same or different amount of force pulling. 同样地,在操作柄271和控制盘238的外表面可标示控制盘238转动角度以及转动方向,在操作柄226的外表面、环形钩状结构272的外表面和控制盘238的外表面可标示操作柄271和操作柄226相对旋转角度及转动方向。 Similarly, the outer surface of the handle 271 and control panel 238 may indicate the control panel 238 and the rotation angle of the rotation direction, on the outer surface of the handle 226, the outer surface of the annular outer surface of the hook structure 238 and control panel 272 may indicate the handle 271 and the handle 226 relative to the rotational angle and rotational direction. 图27E、图27F仅是以四根导向丝70为例进行结构说明的,图27E、图27F所示的设计方案还可以用于扩展用于导向丝70大于等于一根的情况。 FIG. 27E, FIG. 27F is only four wire guide structure 70 illustrated example, FIG. 27E, the design shown in FIG. 27F may also be used to extend the guidewire 70 of a larger than equal.

[0088] 导引导管7也可直接与导引导管控制柄27相连,由导引导管控制柄27负责控制,此时优选导引导管控制柄27能够与控制消融导管I的控制手柄2接合和分拆,图28所示意的设计方案是以图26、图27所示意的设计方案为基础进行改进的,改进的设计方案主要对操作柄226进行了改进,因此对于图28所示意的导引导管控制柄27和控制手柄2的设计方案中与图26、图27所示意的设计方案一致的地方这里就不再赘述。 [0088] The guide catheter 7 can also be directly connected to the guide catheter handle 27, controlled by the guide catheter 27 is responsible for the control handle, the handle case 27 preferably can be guiding catheter ablation catheter control handle to the control I 2 engaged and spin, the design of FIG. 28 is a schematic of FIG 26, FIG 27 is a schematic design for improvement, based on the improved design of the main lever 226 is improved, and therefore FIG. 28 for a schematic guide catheter control handle 27 and the design of the control handle 2 and FIG. 26, FIG. 27 is a schematic uniform design where not repeat them here. 图28是以导引导管控制柄27能够控制导引导管7向ー个方向弯曲的情况下的导引导管控制柄27和控制手柄2的设计方案为例,说明了本发明如何实现将独立的导引导管控制柄27与控制手柄2相互接合和分拆,即实现既可分离使用也可接合使用;其中图28B是导引导管控制柄27的示意图,图28C是控制手柄2的不意图,图28A是两者接合在一起的不意图,图28D、图28E分别是图28A中虚线ccl、cc2横截面放大的截面示意图。 FIG 28 is a guide catheter handle the case where the guide catheter 27 can control the control lever 7 is bent toward the guide catheter 27 and the direction ー design of the control handle 2 as an example, it illustrates how the present invention achieves independence guide catheter handle 27 and the control handle 2 and the split engage each other, i.e., it may also be implemented using either separate joining used; FIG. 28B is a schematic diagram in which the guide catheter handle 27, FIG. 28C is a control handle 2 is not intended, FIG 28A is not intended to be both joined together, FIG. 28D, FIG. 28E respectively CCL dotted line in FIG 28A, an enlarged cross-sectional schematic sectional cc2. 如图28B所示,导引导管控制柄27主要由操作柄271'、操作柄273、控制钮237'组成,操作柄271'与操作柄273操作柄之间的转动可以通过图中虚线矩形框ar所示的由环形钩状结构272和环形钩状结构270相互吻合组成的槽齿滑动结构实现。 , The guide catheter handle of FIG. 28B 27 primarily handle 271 ', an operation lever 273, the control button 237' composition, rotation between the handle 271 'and the handle lever 273 by a broken line rectangle in FIG. hook structure 272 and by an annular ring 270 coincide with each other hook structure consisting of groove teeth sliding structure shown ar achieved. 如图28C所示,控制手柄2主要由操作柄241、环形控制钮250、连接杆251、能量交换接头201组成,操作柄241与环形控制钮250的一起转动的实现方式与图41中提及的方案相同,根据情况设置或不设置液体灌注接头202。 As shown in FIG. 28C, the control handle 2 is mainly composed of the handle 241, an annular control knob 250, connecting rod 251, 201. linker energy exchange, the handle 241 and the annular control knob 250 is rotated together with the implementation of FIG. 41 mentioned the same program, or may not set a liquid filling joint 202 according to the situation. 当导引导管控制柄27与控制手柄2需要接合吋,消融导管I将首先经导引导管控制柄27套入导引导管7,如图28A、图28B、图28C所示,导引导管控制柄27与控制手柄2的接合成为ー个操控手柄主要依靠操作柄273和操作柄241上的可脱槽齿滑动结构,该可脱槽齿滑动结构由操作柄273上的卡槽293、锥柱体凹槽292、卡环297、卡孔299和操作柄241上的可压钩状结构242、锥柱体突出榫243组成。 When the guide catheter 27 and the control lever engages the control handle 2 inches needs, I will first ablation catheter through the guiding catheter handle 27 into the guide catheter sheath 7, as shown in FIG 28A, FIG 28B, as shown in FIG. 28C the guide catheter control a steering lever become engaged ー sliding structure mainly depends on the teeth grooves on the detachable operating handle 273 and the handle 241, the teeth slide structure detachable from the slot groove 293 in the handle 273, the taper shank 27 and the control handle post 2 body groove 292, the collar 297, and engaging holes 299 may be press hook structure 241 on the handle 242, projecting tongue 243 tapered cylinder composition. 如图28A、图28B所示,接合时,将可压钩状结构242对卡槽293,将锥柱体突出榫243对准锥柱体凹槽292,然后推送操作柄241或回压导引导管控制柄27,由于可压钩状结构242头部的压扭294的斜面和卡环297靠操作柄241的斜面相対,可压钩状结构242将顺势进入进入卡槽293,锥柱体突出榫243也将进入锥柱体凹槽292,当操作柄273与操作柄241接近相接触时,可压钩状结构242将弹入由卡环297和操作柄273组成的卡孔299中,由于可压钩状结构242头部的压扭294和卡孔299的限制,导引导管控制柄27与控制手柄2的接合将十分稳定。 FIG 28A, FIG 28B, when joined, will be 242 pairs of slots press hook structure 293, the tapered dovetail projection 243 aligned with the cylinder recesses cone cylinder 292, and then push the handle 241 back pressure or guide catheter handle 27, since the pressing pressure can twisting hook structures 242 of the head 294 of ramp 297 and snap ring against the slant surfaces Dui handle 241, can be pressed into the hook structures 242 into the slot 293 to take advantage of, the cylinder projecting cone the tongue 243 will also enter the tapered recess cartridge 292, when the operating handle 273 and the handle 241 near the contact, can be pressed hook structure 242 into the engaging hole 299 by the elastic snap ring 297 and the handle 273 consisting of, since twisting hook structure can be press pressure limiting aperture 294 and the card 299 of the head 242, the guide catheter engages the handle 27 and the control handle 2 will be very stable. 如图28A、图28B所示,分离时,同时按压相对位置上的两个可压钩状结构242头部的压扭294使其退出卡孔299中,同时顺势推送导引导管控制柄27或回拉操作柄241,由于卡环297的斜面和可压钩状结构242头部的压扭294的斜面相对,压扭294将再次进入卡槽293,随着操作柄273和操作柄241的进ー步远离,可压钩状结构242的头部压扭294将弹出卡槽293,同时锥柱体突出榫243也将退出锥柱体凹槽292,随后消融导管I退出导引导管7,完成分离。 FIG 28A, FIG 28B, when separated, can be pressed simultaneously pressing two positions on the press-torsion relative hook structures 242 of the head 294 so that the card exit hole 299 while pushing homeopathy or guide catheter handle 27 pull-back handle 241, since the inclined surface 297 of the pressure collar and the head of the press-twisting hook structure 242 opposite the inclined surface 294, 294 will enter the slot transpressional 293 again, as the handle 273 and the handle 241 intoー steps away, the head 242 may be pressed hook structure 294 will pop pressure torsion slot 293, while the tapered cylinder 243 projecting tongue grooves will exit cone cylinder 292, and then exit the guiding catheter ablation catheter 7 I, complete separation. 为了使可压钩状结构242能顺利进出卡槽293同时卡槽293又能限制可压钩状结构242的转动,如图28D所示,卡槽293的宽度优选与可压钩状结构242相近,并刚好能卡住可压钩状结构242,而卡槽293的高度优选大于压钮294的厚度。 In order to make the hook structures 242 can be pressed out of the slot 293 can be smoothly while limiting slot 293 can be rotated 242 press hook structure, as shown in FIG. 28D, the width of the slot 293 is preferably pressed with a structure similar to the hook 242 , just to get stuck and can be pressed hook structure 242, the height of the slot 293 is preferably greater than the thickness 294 of the push button. 此外为了实现操作柄273和操作柄241的一起转动,如图28D、图28E所示,可在锥柱体突出榫243与操作柄273之间设置类似图42中虚线矩形框rc所示意的槽齿滑动结构;图28E中虚线大矩形内放大了该结构,其中优选将凹槽295设置在操作柄273上,将突出齿296设置在锥柱体突出榫243上,技术人员根据需要也可以将凹槽295设置在锥柱体突出榫243上,将突出齿296设置在操作柄273上;图28D、图28E中有四个槽齿滑动结构,技术人员根据需要可对其数量和分部进行调整。 Furthermore, in order to realize the operation lever 273 and rotates together with the handle 241, FIG. 28D, FIG. 28E, the projection may be provided similar to the broken line in FIG. 42 rc rectangular frame between the tongue 243 and the handle 273 illustrated in the cone of the cylinder groove tooth sliding structure; the broken line in FIG. 28E amplifies the large rectangle configuration, in which the groove 295 is preferably provided on the operation lever 273, the protruding teeth 296 disposed on the cartridge cone projecting tongue 243, according to the art may be required a groove 295 provided on the cartridge cone projecting tongue 243, protruding teeth 296 disposed on the handle 273; FIG. 28D, FIG. 28E have four toothed sliding groove structure, the number of art and its branches may be necessary Adjustment. 另外,可压钩状结构242优选设置为两个,技术人员根据需要可以进行调整。 Further, pressure may be hook structure 242 is preferably set to two, the art can be adjusted as desired. 类似地,为方便操作导引导管控制柄27,可以在控制钮237'上、操作柄271'上标示控制钮237'的移动距离和移动方向,在控制钮237'上、操作柄271'上、操作柄273上标示操作柄271'与操作柄273相对旋转角度和旋转方向;为了方便导引导管控制柄27与控制手柄2接合,可以在导引导管控制柄27上与控制手柄2上分别标示两者接合的对位线、对位标志等。 'Movement distance and movement direction, the control knob 237' Similarly, to facilitate the operation of the guiding catheter handle 27, control knob 237 may be 'on the operating lever 271' marked on the control button 237 on the handle 271 'on the 2 in order to facilitate the engagement of the guiding catheter handle 27 and the control handle, may be controlled on the guide catheter handle 27 of the handle 2, respectively;, 271 'and 273 relative to the handle rotation angle and the rotation direction of the operation lever 273 indicated on the handle flag bit line joining the two, the positioning marks and the like. 图28仅是以导引导管控制柄27能够控制导引导管7向一个方向弯曲的情况下的导引导管控制柄27与控制手柄2的设计方案为例进行说明的,对于导引导管7能够双向或多向控制弯曲的情况,只需要将图28中的操作柄271'替换成导引导管7能够双向或多向控制弯曲的情况下的操作柄271或操作柄213。 FIG 28 is a guide catheter control only in the case where the control guide catheter 7 can be bent to one direction of the guiding catheter handle 27 and the stem 27 of the control handle design scheme 2 as an example, for the guide catheter can be 7 or bidirectional control of the bending, simply the handle of FIG. 28 271 'can be replaced with a two-way or a guide catheter 7 to the case where the control handle of the bending of the handle 271 or 213. 此外可脱卡榫结构及设计思路还可扩展用于控制手柄2的其他设计方案和其他控制器的设计方案中。 Further detachable tenons may also be extended structure and design ideas for design of the control handle 2 and other designs other controller.

[0089] 若在导引导管控制柄27与控制手柄2融合设计成一个控制手柄2的情况下,需要用导丝引导导引导管7进入血管,优选不封闭导引导管7的头端开口,通过将导丝穿过导引导管7头端开口和导引导管7头部的斜孔74或侧槽76即可引导导引导管7进入血管,对于导引导管7头部的没有设置斜孔74或侧槽76的情况,可以在导引导管7的头部侧壁上设置一个类似图26B所示意的斜孔74,通过将导丝穿过导引导管7头端开口和头部侧壁上的斜孔74即可引导导引导管7进入血管。 [0089] When the fusion guiding catheter handle 27 and the control handle 2 is designed as a case where the control handle 2, it is necessary to guide a guide wire guiding catheter into the blood vessel 7, preferably not closing the guide catheter tip opening 7, by the guidewire through the guide catheter inclined hole 7 and the end opening 74 of the guide catheter head 7 or the side groove 76 to guide the guide catheter into the blood vessel 7, to the guide catheter head 7 is not provided inclined hole 74 or the case-side groove 76, the side walls may be provided on the head of a guide catheter 7 is similar to FIG. 26B is a schematic slant holes 74, through the guide wire through the guide catheter and the head opening 7 side wall end the inclined hole 74 to guide the guide catheter into a blood vessel 7. · ·

[0090] 上述这些控制手柄2和导引导管控制柄27的设计方案中控制手柄2和导引导管控制柄27的外形曲线优选方便人手的持握和控制。 [0090] These designs of the control handle 2 and the guide catheter handle 27 in the control handle 2 and the guide catheter handle profile curve preferably easily hand grip 27 and a control. 控制手柄2和导引导管控制柄27中可能直接或间接与人体体液或组织接触的部分都必须达到相应的与人体体液或组织接触材料的国家标准,对于不能达到上述要求又可能直接或间接与人体体液或组织接触的控制手柄2和导引导管控制柄27的部分,其外面必须用符合与人体体液或组织相接触材料的国家标准的材料包裹。 A control handle 2 and the guide catheter 27 in the handle portion may be directly or indirectly in contact with bodily fluids or tissues must meet with the respective national standards organizations or body fluids in contact with the material, not to meet the above requirements and can be directly or indirectly part of the body or tissue fluids in contact with the control handle 2 and a guiding catheter handle 27, the outer wrapping material must meet national standards of the contact material with the body fluids or tissues. 控制手柄2和导引导管控制柄27可能与人体直接或间接接触部分的制造材料应能够耐受至少一种医用消毒方法。 A control handle 2 and the guide catheter handle 27 and the body directly or may be a method for producing a material indirect contact portions should be able to withstand at least one medical sterilization. 控制手柄2和导引导管控制柄27可能与人体直接或间接接触的部分应该是绝缘的,对于不能达到绝缘要求的地方可以外包裹绝缘材料。 A control handle 2 and the guide catheter 27 handles the part of the body may be direct or indirect contact shall be insulated, insulation requirements can not be achieved to place the overwrap may be an insulating material. 技术人员可以根据实际要求对上述这些控制手柄2和导引导管控制柄27的设计方案进行融合、改进以及交叉使用,这些等效变化和修饰同样落入本发明的实施例权利要求所限定的范围。 In the art can be based on the actual requirements of these designs the control handle 2 and the guide catheter 27 handles integration, and improving cross-use, such equivalent variations and modifications are also within the embodiment of the present invention as claimed in claim defined range .

[0091] 如图I所示,消融发生装置3是为消融导管I、导引导管7、控制手柄2、导引导管控制柄27上需要能量供应的部分提供相应形式的能量,例如当导引导管7需要智能材料改变形状时,消融发生装置3能够提供诱导智能材料改变形状所需要的能量。 [0091] As shown in FIG I, the ablation generator ablation catheter 3 is I, 7 guiding catheter, the control handle 2, the portion of energy supply required guide catheter handle 27 to provide the corresponding forms of energy, for example, when the guide 7 requires a smart catheter material to change shape, an ablation generator 3 to provide smart material inducing the energy required to change the shape. 同时消融发生装置3能够接收和处理消融导管I、导引导管7、控制手柄2、导引导管控制柄27传来的信息,处理后的信息能够部分或全部显示在消融发生装置3的显示器320上,而且该处理后的信息还能够反馈调节消融发生装置3的能量输出。 While ablation generator 3 can receive and process the ablation catheter I, 7 guiding catheter, the control 2, the guide catheter handle 27 handle information transmitted, the information processing section capable of displaying all of the display or generation means 320 of the ablation 3 on, and the information feedback process can also adjust the ablation energy generating means 3 outputs. 消融发生装置3的控制参数能够通过消融发生装置的显示器320进行触屏控制或通过参数设置按钮330进行调节;消融发生装置3应设有能量输出的接头和传感器信号输入的接头311,同时还应设有与外接电源相接的接头321,用于接收由供电电路传来的电能。 The control parameters of the device 3 can be controlled by the ablation touch screen display generating means 320 or adjusted by an ablation parameter setting button 330 occur; ablation generating means 3 to be provided with a joint connector and the sensor signal input 311 of the energy output, while also connector 321 is provided in contact with the external power supply for receiving power transmitted by the power supply circuit. 对于消融导管I、控制手柄2、导引导管7和导引导管控制柄27需要能量供应而又未在控制手柄2或导引导管控制柄27上设有工作开关的设备,在消融发生装置3上优选设有工作开关。 For ablation catheter I, the control handle 2, the guide catheter and guide catheter 7 requires energy supply control stem 27 but not in the control handle 2 is provided with a handle or the guide catheter of the operation switch device 27, an ablation generator 3 preferably provided on the operation switch. 对于消融导管I或/和导引导管7需要的冷却剂、复温剂和灌注液的情况,消融发生装置3或/和导引导管7可以设有灌注器进行自动或手动向消融导管I灌注冷却剂、复温剂和灌注液,此时消融发生装置3应有相应的管路与提供冷却剂、复温剂和灌注液原料或成品的容器相通。 For the case of an ablation catheter I and / or a guide catheter 7 requires coolant, and rewarming agent perfusate ablation 3 and / or guide catheter generating means 7 may be provided with an automatic or manual filling the ablation catheter infusion I coolant, and rewarming agent perfusate, occurs at this time the ablation device 3 should be provided with a respective coolant piping, thawing and perfusion liquid agent container communicates raw or finished material. 对于导引导管7的末端开孔77连接的注液装置设置在消融发生装置3的情況,消融发生装置3应对该注液装置进行控制并设置相应的控制面板或控制按钮。 7 for the ends of the guide catheter the injection openings 77 is provided connecting means in the case of the ablation generator 3, the ablation generating means to cope with this injection apparatus 3 is controlled and set the control panel or control buttons. 消融发生装置3可以是融合上述功能于一体的整机,也可以是分别行使不同功能的分体机,例如将为射频消融电极头9供能的部分独立为ー个分机,将灌注器独立为另ー个分机。 Ablation generating means 3 may be a fusion machine in one of the above-described functions, the respective functions may be split type different functions, for example, for radiofrequency ablation tip portion 9 independently energizing ー extensions, perfusion is independently another ー extensions.

Claims (15)

  1. 1. 一种肾脏去交感神经射频消融导管系统,其特征在于包括: 消融导管(I)、导引导管(7)、控制手柄(2)及消融发生装置(3),其中消融导管(I)由下往上依次包括导管体段(4)和消融段(6);其中所述导管体段(4)与控制手柄(2)相连; 所述消融段(6)包括至少两个独立结构(8),所述独立结构(8)的近端相连,所述消融段(6)至少有ー个独立结构(8)上安装有消融头(9);所述消融头(9)通过导线、导管、微波天线或光纤与控制手柄(2)上的能量交换接头(201)相连,所述能量交换接头(201)通过导线、导管、微波天线或光纤与消融发生装置(3)相连; 所述导引导管(7)通过牵拉或推送一端附着在导引导管(7)头端上,另一端由手柄控制的导引丝(70)控制弯曲;或所述导引导管(7)发生顺应性弯曲或/和设置预制形变; 所述导引导管⑵由导引导管控制柄(27)或 A renal sympathetic denervation radiofrequency ablation catheter system, comprising: an ablation catheter (I), a guide conduit (7), the control handle (2) and an ablation generator (3), wherein the ablation catheter (I) includes, in order from bottom to top catheter body section (4) and the ablation segment (6); at least two separate structures the ablation section (6) comprises (; wherein said catheter body section (4) and the control handle (2) is connected to 8), the proximal end of said freestanding structure (8) is connected to the ablation section (6) at least ー separate structure (8) is attached to the ablation head (9); the ablation head (9) by wires, catheter, optical fiber or microwave antenna and the control handle (2) energy exchange joint (201), said energy exchange joint (201) by a wire, a catheter, optical fiber or microwave ablation antenna generating means (3) is connected; the guiding catheter (7) attached at one end by pulling or pushing on (7) the head end of the guide catheter, the control handle and the other end of the guide wire (70) to control bending; or the guide catheter (7) to conform of bending and / or pre-set deformation; ⑵ the guide catheter from the guiding catheter handle (27) or 制手柄(2)控制以及不通过手柄进行控制。 System handle (2) and is not controlled by the control handle.
  2. 2.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:所述导管体段(4)的远端还包括与消融段(6)近端连接的可控弯曲段(5),所述可控弯曲段(5)发生顺应性弯曲或/和设置预制形变;所述导引导管(7)还包括独立设置或者不独立设置的导引导管控制柄(27)。 The kidneys I according to claim sympathetic radiofrequency ablation catheter system, characterized in that: said catheter body distal end segment (4) further comprises a curved section and controllable ablation section (6) connected to the proximal end ( 5), the curved segments controllable (5) the occurrence of bending compliance and / or pre-set deformation; the guide catheter (7) comprises a further independently provided or not provided independently of the guide catheter handle (27).
  3. 3.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:所述消融导管(I)或/和控制手柄(2)或/和导引导管(7)上还安装有传感器(92)。 The kidneys I according to claim sympathetic radiofrequency ablation catheter system, wherein: said ablation catheter (I) and / or the control handle (2) and / or guide catheter (7) is also mounted on the a sensor (92).
  4. 4.根据权利要求2所述的肾脏去交感神经射频消融导管系统,其特征在于:所述导引导管控制柄(27)上还安装有传感器(92)。 According to claim 2, wherein the renal sympathetic denervation radiofrequency catheter ablation system further comprising: a sensor mounted (92) of the guide catheter handle (27).
  5. 5.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:所述独立结构(8)之间在近端相连,两个独立结构(8)之间包括三种形式:两个独立结构(8)的远端连接为一体而构成消融段头端(17);或者两个独立结构(8)远端彼此独立相互分离;或者两个独立结构(8)的中间部分连接在一起,远端再相互分离。 Kidney I according to claim sympathetic radiofrequency ablation catheter system, wherein: between said freestanding structure (8) is connected at the proximal end, comprising three forms between two separate structures (8): two independent distal end structure (8) is integrally connected to the ablation segment to form the head end (17); two separate structures, or (8) separated from each other independently of the distal end; or two separate structures (8) connected to an intermediate portion together, separated from each other and then the distal end.
  6. 6.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:当导引导管(7)为消融导管(I)形变提供支点吋,导引导管(7)的头部设置与血管相通的斜孔(74)或/和侧槽(76)。 Kidney I according to claim sympathetic radiofrequency ablation catheter system, comprising: a guide catheter when the head (7) providing a fulcrum inch, guiding catheter (7) of ablation catheter (I) provided deformation oblique bore communicating with the vessel (74) and / or side groove (76).
  7. 7.根据权利要求I或5所述的肾脏去交感神经射频消融导管系统,其特征在于: 当独立结构(8)的远端连接为一体而构成消融段头端(17)时,导引导管头端设置缩ロ结构(73)或者堵头(72),导引导管(7)的头部侧壁上设置侧槽(76); 当独立结构(8)彼此独立相互分离时,导引导管(7)的头端或头部侧壁上设置斜孔(74); 当独立结构(8)的中间部分连接在一起,远端再相互分离时,导引导管(7)的头端或头部侧壁设置与血管相通的斜孔(74),斜孔(74)之后导引导管(7)的侧壁上再设置侧槽(76)。 7. I or kidney according to claim 5 sympathetic denervation radiofrequency ablation catheter system, comprising: an independent structure, when the distal end (8) is integrally connected to head-end to form an ablation segment (17), guide catheter ro condensing structure disposed head end (73) or the plug (72), the guide duct (7) of the head-side groove side wall (76); when an independent structure (8) are separated from each other independently of the guiding catheter (7) or the head end with oblique holes (74) on the head side wall; when the intermediate part of the independent structure (8) are connected together, and then separated from each other when the distal end of the guide catheter (7) or the head end of the head then set side groove (76) after the guide catheter portion communicating with the vessel sidewall inclined hole (74), inclined hole (74) (7) of the side wall.
  8. 8.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:当导引导管(7)不为消融导管(I)形变提供支点时,独立结构(8)设置预制形变。 8. The renal sympathetic I according to claim radiofrequency ablation catheter system, wherein: when the guide catheter (7) does not provide a fulcrum for the deformation ablation catheter (I), independently of the structure (8) is provided preform deformation.
  9. 9.根据权利要求I或7所述的肾脏去交感神经射频消融导管系统,其特征在于:还包括可控弯曲段(5)设置预制形变。 According to claim I or claim 7 kidney sympathetic denervation radiofrequency ablation catheter system, characterized by: further comprising a controllable curved section (5) is provided preform deformation.
  10. 10.根据权利要求I所述的所述的肾脏去交感神经射频消融导管系统,其特征在于:所述导引导管(7)的尾部侧壁上还设有用于连接注射器或注液装置进行血管内注药或注射血管内造影剤的开孔(77),或通过导引导管(7)末端开ロ与注射器或/和注液装置相连进行血管内注药或/和注射血管内造影剤;或/和所述导引导管⑵末端设置连接接头(76),连接接头(76)与注射器、注液装置、消融导管(I)或控制手柄(2)连接。 10. I according to claim renal sympathetic radiofrequency ablation catheter system, wherein: the guide is also provided for connecting the syringe or the injection device vascular catheter sidewall on the tail (7) injection or the injection of angiographic Ji opening (77), or open end of the syringe or ro / injection means connected to and intravascular injection and / or by injection Ji angiographic guide catheter (7); or / and the guide catheter tip disposed ⑵ connection joint (76), the connection joint (76) with the syringe, the injection means, ablation catheter (I) or the control handle (2) is connected.
  11. 11.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:所述消融导管(I)或/和导引导管(7)制造时通过选用不同硬度的材料,或者是通过选择性的減少或/和增加部分导管的内部结构或/和管壁的结构。 11. The renal sympathetic I according to claim radiofrequency ablation catheter system, wherein: said ablation catheter (I) and / or guide catheter (7) through the use of different durometer material during manufacture, or by selective reduction of the internal structure or structures or / and the wall portion of the conduit / and increasing.
  12. 12.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:所述消融导管(I)或/和导引导管(7)上标记刻度,以指示消融导管(I)或/和导引导管(7)进入血管的深度以及在超声或X射线影像设备下间接测量人体结构的长度、宽度;消融导管(I)或/和导引导管(7)上设置不同的显影标记用于在超声或X射线影像设备下区分消融导管(I)或/和导引导管(7);或/和各独立结构(8)上设置不同的显影标记用于在超声或X射线影像设备下区分不同的独立结构(8);消融导管(I)或/和导引导管(7)上还设置标记用于在超声或X射线影像设备下区分不同的轴向旋转状态。 12. Renal I according to claim sympathetic radiofrequency ablation catheter system, wherein: said ablation catheter (I) and / or guide catheter (7) marked on the scale to indicate the ablation catheter (I) or depth / and guiding catheter (7) into the vessel body structure and an indirect measurement of the length, the width of the X-ray or ultrasound imaging equipment; ablation catheter (I) and / or guide catheter (7) is provided on a different opaque markers for distinguishing ablation catheter (I) and / or guide catheter (7) in the X-ray or ultrasound imaging equipment; and / or each independently structure (8) provided for different development marked ultrasound or X-ray imaging devices the distinction between different independent structure (8); ablation catheter (I) is also disposed on and / or guide catheter (7) is used in a marker under ultrasound or X-ray imaging device to distinguish between different axial rotation state.
  13. 13.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:消融导管(I)通过导管体段(4)与控制手柄(2)上端固定,控制手柄(2)的下端或下侧面具有能量交换接头(201),来自消融头(9)的导线、导管、微波天线或光纤穿过控制手柄(2)的中心空腔在所述能量交换接头(201)汇集。 13. Renal I according to claim sympathetic radiofrequency ablation catheter system, comprising: an ablation catheter (I) through the catheter body section (4) and the control handle (2) fixed to the upper end of the control handle (2) of the lower end or lower side having energy exchange joint (201), from the ablation head (9) of the wires, catheters, fiber optic or microwave antenna through the control handle (2) of the central cavity in the energy exchange joint (201) together.
  14. 14.根据权利要求I或13所述的肾脏去交感神经射频消融导管系统,其特征在于: 所述控制手柄(2)包括操作柄(241)或/和操作柄(271);或所述控制手柄(2)仅包括操作柄(217); 操作柄(271)上设置有用于控制可控弯曲段(5)形变的控制钮(237)或控制盘(238),所述控制钮(237)或控制盘(238)与导向丝(11)连接,通过控制钮(237)的上下移动,或通过控制盘(238)的多向转动实现对可控弯曲段的控制;或/和包括环形控制钮(250),所述环形控制钮(250)通过连接杆(251)与消融导管(I)连接,所述连接杆(251)位于控制手柄(2)中的导向槽(244)内,通过上下移动环形控制钮(250),实现对独立结构(8)的控制;还包括可防止过度牵拉的缓冲结构; 所述导引导管控制柄(27)包括操作柄(271')和操作柄(273),操作柄(271')上设置有用于控制导引导管(7)形变的控制钮(237' 14. I or kidney according to claim 13 sympathetic denervation radiofrequency ablation catheter system, wherein: said control handle (2) comprises a handle (241) and / or the handle (271); the control or handle (2) comprises only a handle (217); provided on the handle (271) for controlling the controllable bending section (5) deformation control knob (237) or control panel (238), said control knob (237) or control panel (238) and guidewire (11), moved up and down by a control knob (237) or the control panel (238) to effect movement of a plurality of controlled deflection control section; or / and comprises an annular control button (250), said annular control knob (250) connected to the ablation catheter (I) by a connecting rod (251), said connecting rod (251) located in the guide groove of the control handle (244) (2) in the interior, by an annular vertical movement control button (250), to achieve independent control of the structure (8); further comprising a buffer structure prevents excessive traction; said guide catheter handle (27) comprises an operating lever (271 ') and the handle (273), the handle (271 ') is provided for controlling the guide catheter (7) deformation control knob (237' 或控制盘(238'),所述控制钮(237')或控制盘(238')与导向丝(11)连接,通过控制钮(237')的上下移动,或通过控制盘(238')的多向转动实现对导引导管(7)的控制;还包括可防止过度牵拉的缓冲结构;所述导引导管控制柄(27)与控制手柄(2)包括可脱槽齿滑动结构,可脱槽齿滑动结构由操作柄(273)上的卡槽(293)、锥柱体凹槽(292)、卡环(297)、卡孔(299)和操作柄(241)上的可压钩状结构(242)、锥柱体突出榫(243),通过可脱槽齿滑动结构进行分拆与结合。 Or control panel (238 '), said control knob (237') or a control panel (238 ') is connected to the guide wire (11), by a control knob (237' move up and down), or by control panel (238 ') the multi-rotation of the guiding catheter to the control (7); further comprising a buffer structure prevents excessive traction; said guide catheter handle (27) and the control handle (2) comprises a detachable groove teeth sliding structure, tooth structure may slide off the handle from the groove slot (293) on the (273), the groove cartridge cone (292), the collar (297), can be pressed on the card aperture (299) and the handle (241) hook structure (242), projecting tongue cartridge cone (243), joined by a spin-off with detachable teeth sliding groove structure.
  15. 15.根据权利要求I所述的肾脏去交感神经射频消融导管系统,其特征在于:所述消融发生装置(3)设有能量输出的接头和传感器信号输入的接头(311),同时还设有与外接电源相接地接头(321);所述消融发生装置(3)含有通过进行触屏控制来控制參数以及部分或全部信息能显示在其上的显示器(320)和调节參数的按钮(330)。 15. Renal I according to claim sympathetic radiofrequency ablation catheter system, comprising: an ablation said generating means (3) provided with a joint connector and the sensor signal input energy output (311), also provided phase grounding the external power connector (321); the ablation generating means (3) comprising (320) on which a display and buttons to control parameters and some or all information can be displayed by adjusting the control parameters of the touchscreen (330).
CN 201210313087 2012-08-29 2012-08-29 Radio frequency ablation (RFA) catheter system for denervation of renal sympathetic nerves CN102908188B (en)

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