CN102899287B - Method for inducing differentiation from mesenchymal stem cells to cartilage cells and application of mesenchymal stem cells in osteoarthritis - Google Patents
Method for inducing differentiation from mesenchymal stem cells to cartilage cells and application of mesenchymal stem cells in osteoarthritis Download PDFInfo
- Publication number
- CN102899287B CN102899287B CN2012104100476A CN201210410047A CN102899287B CN 102899287 B CN102899287 B CN 102899287B CN 2012104100476 A CN2012104100476 A CN 2012104100476A CN 201210410047 A CN201210410047 A CN 201210410047A CN 102899287 B CN102899287 B CN 102899287B
- Authority
- CN
- China
- Prior art keywords
- cell
- mesenchymal stem
- stem cells
- centrifuge tube
- centrifugal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2012104100476A CN102899287B (en) | 2012-10-24 | 2012-10-24 | Method for inducing differentiation from mesenchymal stem cells to cartilage cells and application of mesenchymal stem cells in osteoarthritis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2012104100476A CN102899287B (en) | 2012-10-24 | 2012-10-24 | Method for inducing differentiation from mesenchymal stem cells to cartilage cells and application of mesenchymal stem cells in osteoarthritis |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102899287A CN102899287A (en) | 2013-01-30 |
CN102899287B true CN102899287B (en) | 2013-08-21 |
Family
ID=47571777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2012104100476A Expired - Fee Related CN102899287B (en) | 2012-10-24 | 2012-10-24 | Method for inducing differentiation from mesenchymal stem cells to cartilage cells and application of mesenchymal stem cells in osteoarthritis |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102899287B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103146645B (en) * | 2013-03-14 | 2015-04-15 | 深圳市博泰生物医学科技发展有限公司 | Method for inducing mesenchymal stem cells (MSCs) into chondrocytes |
CN104096266B (en) * | 2014-07-25 | 2015-12-02 | 中国人民解放军第三军医大学 | Based on tissue engineered bone and the construction process thereof of entochondrostosis system |
CN104771413A (en) * | 2014-12-09 | 2015-07-15 | 周治宇 | Application of arthroscopic flushing fluid sourced mesenchymal stem cells in regenerative repair |
CN104983742A (en) * | 2015-04-22 | 2015-10-21 | 南京康雅生物科技有限公司 | Stem cell preparation for treating degenerative osteoarthropathy and preparation method of stem cell preparation |
CN104988117B (en) * | 2015-07-03 | 2016-06-15 | 深圳中基恒润投资有限公司 | Separate and cultivate mescenchymal stem cell from umbilical cord and to the method for chondrogenic differentiation |
CN104958320A (en) * | 2015-07-29 | 2015-10-07 | 西安芙金细胞科技有限公司 | Cell preparation for treating osteoarthritis and preparation method thereof |
CN105695402A (en) * | 2016-04-14 | 2016-06-22 | 安沂华 | Composition and method for inducing mesenchymal stem cells to be differentiated to cartilage cells |
CN106635968A (en) * | 2016-10-14 | 2017-05-10 | 中卫华医(北京)生物科技有限公司 | Method of inducing and differentiating human umbilical cord derived mesenchymal stem cells into cartilage cells |
CN106834223B (en) * | 2017-04-05 | 2020-03-27 | 上海逍鹏生物科技有限公司 | Method for inducing differentiation of umbilical cord mesenchymal stem cells into chondrocytes |
CN107338218B (en) * | 2017-07-28 | 2020-11-24 | 中国人民解放军总医院第一附属医院 | Differentiation induction medium and method for inducing differentiation of adipose-derived stem cells into chondrocytes |
CN109456939A (en) * | 2018-11-23 | 2019-03-12 | 北京太东生物科技有限公司 | Culture medium used in cultural method and this method of the inducing umbilical cord mesenchymal stem at cartilage differentiation |
CN109825469A (en) * | 2019-03-09 | 2019-05-31 | 和携科技(北京)有限公司 | A kind of promotion abductive approach of the source of people umbilical cord mesenchymal stem cells to Chondrocyte Differentiation |
CN110747165A (en) * | 2019-11-19 | 2020-02-04 | 山东省齐鲁细胞治疗工程技术有限公司 | Preparation method and application of mesenchymal stem cell scaffold-free three-dimensional gel |
CN115369079B (en) * | 2022-06-22 | 2023-10-13 | 广东省科学院生物与医学工程研究所 | Composition and application thereof in preparation of cell thin film |
CN117431209A (en) * | 2023-12-22 | 2024-01-23 | 上海元戊医学技术有限公司 | Method for preparing mesenchymal stem cells through neural crest cell line and application of mesenchymal stem cells as osteoarthritis medicine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7459307B2 (en) * | 2001-08-14 | 2008-12-02 | Medipost Co., Ltd | Composition for treatment of articular cartilage damage |
US20100119577A1 (en) * | 2007-05-06 | 2010-05-13 | Byoung-Hyun Min | Therapeutic composite for cartilage disorder using extracellular matrix (ecm) scaffold |
CN101543644B (en) * | 2008-03-27 | 2012-07-25 | 中国人民解放军总医院 | Constructing method of bracket-free engineering cartilaginous tissue and product thereof |
US8574614B2 (en) * | 2010-02-04 | 2013-11-05 | Hwa-Chang Liu | Surgical grafts for repairing chondral defects |
-
2012
- 2012-10-24 CN CN2012104100476A patent/CN102899287B/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN102899287A (en) | 2013-01-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102899287B (en) | Method for inducing differentiation from mesenchymal stem cells to cartilage cells and application of mesenchymal stem cells in osteoarthritis | |
CN103060264B (en) | Stem cell culture medium and application thereof and stem cell cultivation method | |
CN103243070B (en) | Stem cell medium and application thereof | |
US20150118748A1 (en) | High-concentration stem cell production method | |
CN104877964A (en) | In vitro construction method for salivary glands organs and acinus | |
CN107338218A (en) | Derivant and method of a kind of induced lipolysis stem cell to Chondrocyte Differentiation | |
CN104450611A (en) | Primary separation and culture method of human amniotic mesenchymal stem cells | |
CN110938590B (en) | Mesenchymal stem cell serum-free medium and application thereof | |
CN103881971B (en) | Culture medium for culturing and/or amplifying mesenchymal stem cells and culture method thereof | |
CN105647856A (en) | Method for promoting hUCMSCs (human umbilical cord mesenchymal stem cells) to differentiate into cartilage cells | |
CN107267453A (en) | A kind of culture medium and its application for being used to cultivate fat mesenchymal stem cell | |
CN103881973A (en) | Mesenchymal stem cell induction differentiation medium and method | |
CN105132360A (en) | Method for inducing placenta-derived mesenchymal stem cells to be differentiated into islet-like cells | |
CN113692282A (en) | Bioactive substance composition, serum-free culture medium containing composition and application of serum-free culture medium | |
CN1778905B (en) | Separating culture and use for fatty mesenchymal dry cell | |
CN104758923A (en) | Stem cell preparation for treating nerve injury and preparation method thereof | |
CN106566803A (en) | Culture solution, application of culture solution and method for culturing umbilical cord mesenchymal stem cells | |
CN102965338A (en) | Extraction and culture method of human umbilical cord mesenchymal stem cells | |
CN102146359A (en) | Method for extracting original mesenchymal stem cells from placenta and serum-free amplification | |
CN107287156A (en) | A kind of isolated culture method of fat mesenchymal stem cell and its application | |
CN106282102A (en) | Animal mesenchymal stem cell serum-free culture fluid | |
WO2021098025A1 (en) | Method for in-vitro activation of adipose stem cells to transform into proto-chondrocytes | |
CN103087992A (en) | Improved adipose-derived stem cells for cartilage injury repair | |
CN106282113A (en) | A kind of method utilizing serum-free medium to pass through transdifferentiation acquisition neurocyte | |
CN105193848A (en) | Stem cell preparation for treating aplastic anemia and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20130130 Assignee: Heilongjiang Ze North Biotechnology Co., Ltd. Assignor: Tianjin Heze Stem Cell Technology Co.,Ltd. Contract record no.: 2014120000076 Denomination of invention: Method for inducing differentiation from mesenchymal stem cells to cartilage cells and application of mesenchymal stem cells in osteoarthritis Granted publication date: 20130821 License type: Exclusive License Record date: 20140903 |
|
LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20170801 Address after: 150000, Heilongjiang hi tech Zone, Harbin science and technology innovation city, innovation and entrepreneurship Plaza, building 11, science and Technology Street, No. 999, E1-2 layer Patentee after: Heilongjiang Ze North Biotechnology Co., Ltd. Address before: 300381 Tianjin City, Hexi District airport economic zone two West Road No. 82 Laguna podium two layer 202-B078 Patentee before: Tianjin Heze Stem Cell Technology Co.,Ltd. |
|
TR01 | Transfer of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130821 Termination date: 20181024 |
|
CF01 | Termination of patent right due to non-payment of annual fee |