CN102846884A - Analgesia plaster and preparation method thereof - Google Patents

Abstract

The present invention discloses an analgesic plaster and a preparation method thereof. The analgesic plaster is prepared from the following raw material drugs, by weight, 8-18 parts of common monkshood mother-root, 8-18 parts of kusnezoff monkshood mother-root, 10-18 parts of Chinese honeylocust fruit, 5-7 parts of safflower, 10-15 parts of angelica archang lica, 6-12 parts of common threewingnut root, 10-18 parts of incised notopterygium rhizome and root, 6-10 parts of frankincense, 6-10 parts of myrrh, 0.5-2 parts of borneol, 0.5-3 parts of camphor, and 7-15 parts of giant typhonium tuber. The preparation method comprises the following steps: a, mixing the common monkshood mother-root, the kusnezoff monkshood mother-root, the Chinese honeylocust fruit, the safflower, the angelica archang lica, the common threewingnut root, the incised notopterygium rhizome and root, the frankincense, the myrrh, and the giant typhonium tuber according to the weight parts, and crushing into drug powder with a particles size of more than 30 meshes; b, soaking the drug powder for 3-10 days with an alcohol with an alcoholicity of 75-95 DEG; c, heating the resulting mixture of the drug powder and the alcohol in the step b, and decocting into a pasty material; and d, adding the borneol and the camphor powder to the pasty material in the step c. During use, the analgesic plaster is placed in gauze, wherein each piece of the gauze is added with 10-20 g of the analgesic plaster to be used in a moisturizing state.

Description

A kind of analgesic plaster and preparation method thereof

Technical field

The invention belongs to the Chinese drug preparation technique field, be specially a kind ofly invigorate blood circulation, detumescence, pain relieving, Shujin, active plaster.

Background technology

Rheumatism, rheumatoid arthritis, hyperosteogeny, neck, lumbar vertebra, traumatic injury etc. can cause pain, cause suffering to the patient.Pain not only affects quality of life, has the people also can produce mental illness owing to long-term pain can not get effective treatment.A lot of pain-suffered patients become the painful diseases of refractory because untimely treatment makes local long-term general pain be converted into complicated local pain syndrome or central pain.General analgesic has aspirin, ibuprofen, indometacin, acetaminophen, Phenylbutazone, rofecoxib, celecoxib etc.Analgesic is taken too much can cause gastrointestinal upset, chronic interstitial nephritis, necrosis of renal papillae, renal insufficiency etc.

Summary of the invention

The purpose of this invention is to provide a kind of analgesic plaster and preparation method thereof.

Analgesic plaster of the present invention, by the crude drug of following parts by weight: 7～15 parts of 8～18 parts of Radix Aconitis, 8～18 parts of Radix Aconiti Kusnezoffii, 10～18 parts of Fructus Gleditsia, 5～7 parts on Flos Carthami, 10～15 parts of the Radixs Angelicae Dahuricae, 6～12 parts of Radix Tripterygii Wilfordiis, 10～18 parts of Rhizoma Et Radix Notopterygiis, 6～10 parts of Olibanums, 6～10 parts of Myrrhas, 0.5～2 part of Borneolum Syntheticum, 0.5～3 part of Camphora, Rhizoma Typhonii are made.Can be by the crude drug of following parts by weight as optimizing also: 10 parts of 13 parts of Radix Aconitis, 13 parts of Radix Aconiti Kusnezoffii, 14 parts of Fructus Gleditsia, 6 parts on Flos Carthami, 13 parts of the Radixs Angelicae Dahuricae, 9 parts of Radix Tripterygii Wilfordiis, 14 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Olibanums, 8 parts of Myrrhas, 1.5 parts of Borneolum Syntheticums, 1.8 parts of Camphoras, Rhizoma Typhonii be made.

The preparation method of this analgesic plaster may further comprise the steps:

A, Radix Aconiti, Radix Aconiti Kusnezoffii, Fructus Gleditsia, Flos Carthami, the Radix Angelicae Dahuricae, Radix Tripterygii Wilfordii, Rhizoma Et Radix Notopterygii, Olibanum, Myrrha, Rhizoma Typhonii are mixed according to described parts by weight, be ground into the above medicated powder of 30 orders;

B, described medicated powder is alcohol-pickled 3～10 days with 75 °～95 °;

C, with the medicated powder crude alcohol mixture among the step b, heating is brewed into pasty state;

D, in the pastel of step c, add Borneolum Syntheticum, Camphora powder.

Put into gauze during use, the moisturizing of every 10～20 gram is used, and also can be combined with other substrate.

In the analgesic plaster prescription of the present invention, the Radix Aconiti expelling wind and removing dampness, antalgic is had a pain for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type; Radix Aconiti Kusnezoffii is searched wind prevailing over dampness, and dispersing cold for relieving pain is opened expectorant, and detumescence is controlled anemofrigid-damp arthralgia, paralysis due to windstroke, tetanus, wind syndrome of head, coldness and pain in the epigastrium, accumulation of phlegm in the hypochondrium, air parcel, cold-dysentery, sore throat, carbuncle, furuncle, scrofula; The Fructus Gleditsia expelling phlegm for arresting cough, logical the closing of having one's ideas straightened out, the parasite killing eliminating stagnation is controlled the productive cough dyspnea with fullness of the chest, the apoplexy locked mouth, accumulation and obstruction of sputum, coma in silence, epilepsy, sore throat, constipation and anuresis, carbuncle scabies; Flos Carthami invigorate blood circulation latus rectum, eliminating stasis to stop pain are used for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.Radix Angelicae Dahuricae wind-damp dispelling, the evacuation of pus of invigorating blood circulation, the granulation promoting pain relieving is used for headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus; Radix Tripterygii Wilfordii is dispeled the wind, detoxifcation, and parasite killing, the external treating rheumatic arthritis, skin is itched, and kills maggot, wriggler, water-snail eradication, malicious Mus; The Rhizoma Et Radix Notopterygii exterior cold of faling apart, wind-damp dispelling, sharp joint, pain relieving, main affection of exogenous wind-cold, it is lossless to have a headache, mimeograph cold-damp numbness, edema due to wind pathogen edema, sore swollen toxin; The Olibanum regulating qi and activating blood, analgesic therapy chases after poison, controls coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge; The Myrrha blood blood stasis removing that falls apart, subduing swelling and relieving pain is controlled traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye; Borneolum Syntheticum leads to all keys, loose stagnated fire, and removing nebula makes eye bright, and reducing swelling and alleviating pain is controlled the apoplexy locked mouth, the calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is the nebula film also, enterobiasis; Camphora dehumidifying parasite killing, warming and odynolysis has one's ideas straightened out that it is dirty to ward off, and cures mainly scabies pruritus, traumatic pain, toothache; The Rhizoma Typhonii expectorant that dispels the wind, the meridian dredging, the spasmolytic pain relieving, powder detoxifcation cures mainly middle wind-phlegm and stops up, facial hemiparalysis, hemiplegia, tetanus, headache, rheumatic arthralgia, numb limbs and tense tendons, scrofula tuberculosis, carbuncle of yin nature toxic swelling, venom.All medicine compatibilities are invigorated blood circulation, detumescence, pain relieving, Shujin, active; The pain for the treatment of rheumatism, rheumatoid arthritis, hyperosteogeny, neck, lumbar vertebra, traumatic injury etc. is evident in efficacy.This analgesic plaster adopts the mode of decocting in water to make, and is easy to clean, and is difficult for causing the reactions such as irritated.

Relevant clinical data is as follows: in 45 cases, and male's 24 examples, women's 21 examples; Oldest 57 years old, minimum 19 years old, wherein the elder of the course of disease is 15 years, and was the shortest 3 days.

Therapeutic Method: according to the size of local pain area, the cream of getting it filled is an amount of, be spread out on the white gauze, thick about 0.3cm～0.5cm, the external application affected part, bandage or immobilization with adhesive tape in functional position, lifting affected limb was changed dressings 1 time in 2 days.

Criterion of therapeutical effect: recovery from illness: red, swollen, hot, bitterly disappearance, accompanying or adjacent joints activity are freely; Produce effects: red, swollen, heat disappears, and slightly aches, and is accompanying or the adjacent joints activity is substantially not limited; Effectively: red, swollen, hot, alleviation of pain is light, accompanying or the adjacent joints activity is slightly limited; Invalid; Red, swollen, hot, pain nothing is improved, and joint motion is limited.

Curative effect statistical result is as follows after the case treatment:

Group

The example number

Cure (n%)

Produce effects (n%)

Effectively (n%)

Invalid (n%)

Total effective rate (n%)

Treatment group

45

19（42.2）

15（33.3）

10（22.2）

1（2.2）

97.8

The specific embodiment

The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; content still belongs to protection scope of the present invention to nonessential improvement and adjustment more of the present invention to those skilled in the art according to the present invention.

Embodiment 1: get Radix Aconiti 13 grams, Radix Aconiti Kusnezoffii 13 grams, Fructus Gleditsia 14 grams, Flos Carthami 6 grams, the Radix Angelicae Dahuricae 13 grams, Radix Tripterygii Wilfordii 9 grams, Rhizoma Et Radix Notopterygii 14 grams, Olibanum 8 grams, Myrrha 8 grams, Rhizoma Typhonii 10 grams, Radix Aconiti, Radix Aconiti Kusnezoffii, Fructus Gleditsia, Flos Carthami, the Radix Angelicae Dahuricae, Radix Tripterygii Wilfordii, Rhizoma Et Radix Notopterygii, Olibanum, Myrrha, Borneolum Syntheticum, Camphora, Rhizoma Typhonii are mixed according to described parts by weight, be ground into 30 purpose medicated powder; Described medicated powder is alcohol-pickled 7 days with 80 °; Till boiling medicated powder crude alcohol mixture heating when treating that medicine becomes into pasty state, add 1.5 gram borneol powder, 1.8 gram Camphora powder, medicine is placed in the middle of the gauze according to every 15 gram, the moisturizing sealing is preserved.

Embodiment 2: get Radix Aconiti 8 grams, Radix Aconiti Kusnezoffii 8 grams, Fructus Gleditsia 10 grams, Flos Carthami 5 grams, the Radix Angelicae Dahuricae 10 grams, Radix Tripterygii Wilfordii 6 grams, Rhizoma Et Radix Notopterygii 10 grams, Olibanum 6 grams, Myrrha 6 grams, Rhizoma Typhonii 7 grams, Radix Aconiti, Radix Aconiti Kusnezoffii, Fructus Gleditsia, Flos Carthami, the Radix Angelicae Dahuricae, Radix Tripterygii Wilfordii, Rhizoma Et Radix Notopterygii, Olibanum, Myrrha, Borneolum Syntheticum, Camphora, Rhizoma Typhonii are mixed according to described parts by weight, be ground into 40 purpose medicated powder; Described medicated powder is alcohol-pickled 3 days with 75 °; Till boiling medicated powder crude alcohol mixture heating when treating that medicine becomes into pasty state, add 0.5 gram borneol powder, 0.5 gram Camphora powder, medicine is placed in the middle of the gauze according to every 10 gram, the moisturizing sealing is preserved.

Embodiment 3: get Radix Aconiti 18 grams, Radix Aconiti Kusnezoffii 18 grams, Fructus Gleditsia 18 grams, Flos Carthami 7 grams, the Radix Angelicae Dahuricae 15 grams, Radix Tripterygii Wilfordii 12 grams, Rhizoma Et Radix Notopterygii 18 grams, Olibanum 10 grams, Myrrha 10 grams, Rhizoma Typhonii 15 grams, Radix Aconiti, Radix Aconiti Kusnezoffii, Fructus Gleditsia, Flos Carthami, the Radix Angelicae Dahuricae, Radix Tripterygii Wilfordii, Rhizoma Et Radix Notopterygii, Olibanum, Myrrha, Borneolum Syntheticum, Camphora, Rhizoma Typhonii are mixed according to described parts by weight, be ground into 50 purpose medicated powder; Described medicated powder is alcohol-pickled 10 days with 95 °; Till boiling medicated powder crude alcohol mixture heating when treating that medicine becomes into pasty state, add 2 gram borneol powder, 3 gram Camphora powder, medicine is placed in the middle of the gauze according to every 20 gram, the moisturizing sealing is preserved.

In addition, plaster also can other substrate of proportioning use together.

Claims (3)

1. analgesic plaster it is characterized in that the crude drug by following parts by weight: 7～15 parts of 8～18 parts of Radix Aconitis, 8～18 parts of Radix Aconiti Kusnezoffii, 10～18 parts of Fructus Gleditsia, 5～7 parts on Flos Carthami, 10～15 parts of the Radixs Angelicae Dahuricae, 6～12 parts of Radix Tripterygii Wilfordiis, 10～18 parts of Rhizoma Et Radix Notopterygiis, 6～10 parts of Olibanums, 6～10 parts of Myrrhas, 0.5～2 part of Borneolum Syntheticum, 0.5～3 part of Camphora, Rhizoma Typhonii are made.

2. analgesic plaster according to claim 1 it is characterized in that the crude drug by following parts by weight: 10 parts of 13 parts of Radix Aconitis, 13 parts of Radix Aconiti Kusnezoffii, 14 parts of Fructus Gleditsia, 6 parts on Flos Carthami, 13 parts of the Radixs Angelicae Dahuricae, 9 parts of Radix Tripterygii Wilfordiis, 14 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Olibanums, 8 parts of Myrrhas, 1.5 parts of Borneolum Syntheticums, 1.8 parts of Camphoras, Rhizoma Typhonii are made.

3. method for preparing the described analgesic plaster of claim 1 is characterized in that may further comprise the steps:

A, Radix Aconiti, Radix Aconiti Kusnezoffii, Fructus Gleditsia, Flos Carthami, the Radix Angelicae Dahuricae, Radix Tripterygii Wilfordii, Rhizoma Et Radix Notopterygii, Olibanum, Myrrha, Rhizoma Typhonii are mixed according to described parts by weight, be ground into the above medicated powder of 30 orders;

B, described medicated powder is alcohol-pickled 3～10 days with 75 °～95 °;

C, with the medicated powder crude alcohol mixture among the step b, heating is brewed into pasty state;

D, add described parts by weight Borneolum Syntheticum, Camphora powder in the pastel of step c.