CN102813768B - Production method of Arisaema cum Bile and device thereof - Google Patents

Production method of Arisaema cum Bile and device thereof Download PDF

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Publication number
CN102813768B
CN102813768B CN201210232072.XA CN201210232072A CN102813768B CN 102813768 B CN102813768 B CN 102813768B CN 201210232072 A CN201210232072 A CN 201210232072A CN 102813768 B CN102813768 B CN 102813768B
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China
Prior art keywords
arisaema cum
screw extruder
cum bile
type screw
production method
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Expired - Fee Related
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CN201210232072.XA
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CN102813768A (en
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罗明
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SICHUAN BAISHENG PHARMACEUTICAL CO Ltd
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SICHUAN BAISHENG PHARMACEUTICAL CO Ltd
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Abstract

The invention discloses a production method of Arisaema cum Bile and a device thereof. According to a present method for preparation of Arisaema cum Bile, raw Rhizoma Arisaematis fine powder and cattle, sheep or swine bile are fermented to a white color, and the finally-prepared product is also white and soft in texture and dose not accord with the quality standard in Chinese Pharmacopeia. The invention aims to solve the above problem existing in the present method. The method provided by the invention comprises the following steps of: a, mixing raw Rhizoma Arisaematis fine powder and bile, and fermenting; b, sending the fermented material into a duct-type screw extruder for slaking; and c, outputting the slaked material out through an opening of the duct-type screw extruder, and conveying the outputted material into a slicer through a transmission band for slicing, so as to obtain the product. The production method provided by the invention is ingeniously designed, is convenient to operate, and can be used to effectively simplify technological process, minimize labor intensity, save manpower cost, shorten production period and reduce drug production cost. The materials provided by the invention have good moulding effects, and the prepared Arisaema cum Bile is hard in texture, contains no starch granules and accords with related state standards.

Description

A kind of production method of Arisaema Cum Bile and device
Technical field
The present invention relates to medicine preparation field, especially a kind of production method of Arisaema Cum Bile and device.
Background technology
Arisaema Cum Bile records in 2010 editions Chinese Pharmacopoeia quality standards, its bitter in the mouth, micro-pungent, cool; Have removing heat-phlegm, the effect of dispelling wind and relieving convulsion, is mainly used in phlegm-heat cough, cough up phlegm yellow thick, and middle wind-phlegm fan, demented infantile convulsion.Its preparation method is as follows: the fine powder of Rhizoma Arisaematis (processed) and cattle, sheep or Fel Sus domestica process from strand, or is that Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica process through fermentation., in Chinese Pharmacopoeia quality standard, stipulate, the Arisaema Cum Bile character of preparation is as follows: this product is square shape or cylindric meanwhile; Brown color, taupe brown or brownish black; Matter is hard; Feeble QI raw meat, bitter in the mouth.
At present, in the actual production of Arisaema Cum Bile, conventionally adopt Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica to process through fermentation.Yet applicant finds in practice, while adopting the method to prepare Arisaema Cum Bile, Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica are after fermentation, and color be white, and finally prepared product is also white in color, and quality softness, does not meet Chinese Pharmacopoeia quality standard.
Summary of the invention
Goal of the invention of the present invention is: while preparing Arisaema Cum Bile for existing method, Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica are after fermentation, and color is white, final prepared product is also white in color, and quality is soft, does not meet the problem of Chinese Pharmacopoeia quality standard, a kind of production method and device of Arisaema Cum Bile are provided, the present invention is skillfully constructed, easy to operate, effectively simplification of flowsheet, reduce labor intensity, save human cost, shorten the production cycle, reduce pharmaceutical production cost.Material forming in the present invention is effective, and prepared Arisaema Cum Bile quality is hard, and not starch-containing grain, meets relevant national standard.
To achieve these goals, the present invention adopts following technical scheme:.
A production method for Arisaema Cum Bile, comprises the steps:
A, Arisaema Cum Bile fine powder is mixed with bile after, ferment;
B, by fermentation after material send in duct type screw extruder, make material be warming up to 130-150 ℃, carry out ripening;
Material after c, ripening is exported by the opening of duct type screw extruder, and the material of output is transported in microtome and is cut into slices by transport tape, obtains product;
Described bile is one or more in Fel Bovis seu Bubali, sheep bile, Fel Sus domestica.
In described step b, the material after fermentation is sent in duct type screw extruder, under the screw acting of duct type screw extruder, made material be warming up to 130-150 ℃.
In described step c, opening is circle or polygon.
The device that is used for the production method of above-mentioned Arisaema Cum Bile, comprise duct type screw extruder, the microtome being connected with duct type screw extruder by transport tape, on described duct type screw extruder, be respectively arranged with hopper, opening, in described duct type screw extruder, be provided with screw rod, described screw rod is connected with motor.
Described opening is circle or polygon.
On described duct type screw extruder, be provided with heater.
Described heater is electric heater.
Described heater is heating thin film.
Described heater is tubulose calandria.
The present invention after first just Arisaema Cum Bile fine powder mixes with bile, is fermented.The material after fermentation is sent in duct type screw extruder, the rotation of the screw rod of duct type screw extruder, pushes material, makes material be warming up to 130-150 ℃ again.By screw acting, thereby make material ripening, meanwhile, due to the effect of screw rod, the material after ripening is easy-formation more, and prepared Arisaema Cum Bile quality is more hard.Material after ripening is exported by the opening of duct type screw extruder, and the material of output is transported in microtome by transport tape.In the process of carrying, material and surrounding air heat exchange, thereby natural cooling.Cooled material is cut into slices through microtome, obtains product.In spring and summer season, ambient temperature is higher, by screw acting, can make material be warming up to 130-150 ℃, meets needs of production; In autumn and winter season, ambient temperature is lower, effect at screw rod, the temperature of material can not reach 130-150 ℃, and therefore, the present invention is also provided with heater on duct type screw extruder, heater is a kind of in electric heater or heating thin film or tubulose calandria, by heater, can make material be warming up to 130-150 ℃, thereby meet needs of production.
The present invention is skillfully constructed, and by the screw acting of duct type screw extruder, thereby makes material be warming up to 130-150 ℃, completes the ripening to material.The present invention's opening is set to circle, and the material after ripening is exported by the opening of duct type screw extruder, is cylindric, then after transport tape is cooling, through microtome section, obtains product.In Arisaema Cum Bile prepared by the present invention, not starch-containing grain, can effectively reduce labor intensity simultaneously, and simplification of flowsheet is saved production time and production cost.In the present invention, the temperature of material ripening is controlled, and material forming is effective simultaneously, and prepared product quality is hard, meets relevant national standard
In sum, owing to having adopted technique scheme, the invention has the beneficial effects as follows:
1, the present invention is skillfully constructed, simple in structure, easy to operate, and effectively simplification of flowsheet, reduces labor intensity, saves human cost, shortens the production cycle, reduces pharmaceutical production cost;
2, the present invention rotates by the screw rod of duct type screw extruder, material is pushed, thereby make material be warming up to 130-150 ℃, complete maturing process, simultaneously, effect due to screw rod, material after ripening is easy-formation more, and prepared Arisaema Cum Bile quality is more hard, thereby when effectively solving existing method and preparing Arisaema Cum Bile, it is white in color, the problem of quality softness;
3, the present invention is connected with microtome duct type screw extruder by transport tape, thereby completes cooling, the section molding of material, has effectively improved the production efficiency of Arisaema Cum Bile;
4, the present invention is also provided with heater on duct type screw extruder, thereby while meeting autumn and winter season, the needs that Arisaema Cum Bile is produced;
5, the material forming in the present invention is effective, and prepared Arisaema Cum Bile quality is hard, and not starch-containing grain, meets relevant national standard.
Accompanying drawing explanation
Examples of the present invention will be described by way of reference to the accompanying drawings, wherein:
Fig. 1 is the structural representation of device of the present invention.
Fig. 2 is the schematic diagram of the opening part of duct type screw extruder in the present invention.
Labelling in figure: 1 is duct type screw extruder, 2 is transport tape, and 3 is microtome, and 4 is hopper, and 5 is opening, and 6 is screw rod, and 7 is motor, and 8 is heater.
The specific embodiment
Disclosed all features in this description, or the step in disclosed all methods or process, except mutually exclusive feature and/or step, all can combine by any way.
Disclosed arbitrary feature in this description, unless narration especially all can be replaced by other equivalences or the alternative features with similar object.That is,, unless narration especially, each feature is an example in a series of equivalences or similar characteristics.
In the present invention, the device of employing as shown in the figure.This device comprises duct type screw extruder 1, the microtome 3 being connected with duct type screw extruder 1 by transport tape 2.On duct type screw extruder 1, be provided with hopper 4, be provided with screw rod 6 in duct type screw extruder 1, screw rod 6 is connected with motor 7, and one end of duct type screw extruder 1 is provided with opening 5, and opening 5 is circular.On duct type screw extruder 1, be also provided with heater 8, heater 8 is electric heater.
Embodiment 1
A production method for Arisaema Cum Bile, comprises the steps:
(1) after Arisaema Cum Bile fine powder is mixed with Fel Bovis seu Bubali, ferment;
(2) material after fermentation is sent in duct type screw extruder 1 by hopper 4, screw rod 6 rotates under the drive of motor 7, material is pushed, and material is warming up to 130 ℃, thereby make material ripening;
(3) material after ripening is by circular open 5 outputs of duct type screw extruder 1, and the material of output is cylindric, through transport tape 2, is transported to section in microtome 3, obtains product.
After measured, the Arisaema Cum Bile that prepared by the present embodiment is brown color; Matter is hard; Feeble QI raw meat, bitter in the mouth; All the other indices all meet national standard.
Embodiment 2
A production method for Arisaema Cum Bile, comprises the steps:
(1) after Arisaema Cum Bile fine powder is mixed with sheep bile, ferment;
(2) material after fermentation is sent in duct type screw extruder 1 by hopper 4, screw rod 6 rotates under the drive of motor 7, and material is pushed, and opens heater 8 simultaneously, and material is heated, and makes material be warming up to 150 ℃, thereby makes material ripening;
(3) material after ripening is by circular open 5 outputs of duct type screw extruder 1, and the material of output is cylindric, through transport tape 2, is transported to section in microtome 3, obtains product.
After measured, the Arisaema Cum Bile that prepared by the present embodiment is brownish black; Matter is hard; Feeble QI raw meat, bitter in the mouth; All the other indices all meet national standard.
Embodiment 3
A production method for Arisaema Cum Bile, comprises the steps:
(1) after Arisaema Cum Bile fine powder is mixed with Fel Sus domestica, ferment;
(2) material after fermentation is sent in duct type screw extruder 1 by hopper 4, screw rod 6 rotates under the drive of motor 7, and material is pushed, and after tested, the temperature of duct type screw extruder 1 interior material is 135 ℃, thereby makes material ripening;
(3) material after ripening is by circular open 5 outputs of duct type screw extruder 1, and the material of output is cylindric, through transport tape 2, is transported to section in microtome 3, obtains product.
After measured, the Arisaema Cum Bile that prepared by the present embodiment is taupe brown; Matter is hard; Feeble QI raw meat, bitter in the mouth; All the other indices all meet national standard.
The present invention is not limited to the aforesaid specific embodiment.The present invention expands to any new feature or any new combination disclosing in this manual, and the arbitrary new method disclosing or step or any new combination of process.

Claims (9)

1. a production method for Arisaema Cum Bile, is characterized in that, comprises the steps:
A, Arisaema Cum Bile fine powder is mixed with bile after, ferment;
B, by fermentation after material send in duct type screw extruder, make material be warming up to 130-150 ℃, carry out ripening;
Material after c, ripening is exported by the opening of duct type screw extruder, and the material of output is transported in microtome and is cut into slices by transport tape, obtains product;
Described bile is one or more in Fel Bovis seu Bubali, sheep bile, Fel Sus domestica.
2. the production method of Arisaema Cum Bile according to claim 1, is characterized in that, in described step b, the material after fermentation is sent in duct type screw extruder, under the screw acting of duct type screw extruder, makes material be warming up to 130-150 ℃.
3. the production method of Arisaema Cum Bile according to claim 1, is characterized in that, in described step c, opening is circle or polygon.
4. for the device of the production method of the arbitrary described Arisaema Cum Bile of claim 1-3, it is characterized in that: comprise duct type screw extruder, the microtome being connected with duct type screw extruder by transport tape, on described duct type screw extruder, be respectively arranged with hopper, opening, in described duct type screw extruder, be provided with screw rod, described screw rod is connected with motor.
5. the device of the production method of Arisaema Cum Bile according to claim 4, is characterized in that, described opening is circle or polygon.
6. the device of the production method of Arisaema Cum Bile according to claim 4, is characterized in that, on described duct type screw extruder, is provided with heater.
7. the device of the production method of Arisaema Cum Bile according to claim 6, is characterized in that, described heater is electric heater.
8. the device of the production method of Arisaema Cum Bile according to claim 6, is characterized in that, described heater is heating thin film.
9. the device of the production method of Arisaema Cum Bile according to claim 6, is characterized in that, described heater is tubulose calandria.
CN201210232072.XA 2012-07-06 2012-07-06 Production method of Arisaema cum Bile and device thereof Expired - Fee Related CN102813768B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107596040A (en) * 2017-10-13 2018-01-19 河南省三禾药业有限公司 A kind of rhizoma arisaematis processed product and its concocting method
CN113769000B (en) * 2021-08-27 2022-05-06 四川百胜药业有限公司 Preparation method of Arisaema cum bile and Arisaema cum bile

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102186365A (en) * 2008-10-17 2011-09-14 英美烟草(德国)有限公司 Modular tobacco preparation including extrusion

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102186365A (en) * 2008-10-17 2011-09-14 英美烟草(德国)有限公司 Modular tobacco preparation including extrusion

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
《天南星炮制历史沿革的探讨》;全卫国等;《中成药》;19881020(第10期);全文 *
《胆南星的制备方法改进》;高万山;《中国中药杂志》;19860825(第08期);全文 *
全卫国等.《天南星炮制历史沿革的探讨》.《中成药》.1988,(第10期),
高万山.《胆南星的制备方法改进》.《中国中药杂志》.1986,(第08期),

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