CN102784129A - Preparation process of traditional Chinese medicine plaster - Google Patents
Preparation process of traditional Chinese medicine plaster Download PDFInfo
- Publication number
- CN102784129A CN102784129A CN2012102805063A CN201210280506A CN102784129A CN 102784129 A CN102784129 A CN 102784129A CN 2012102805063 A CN2012102805063 A CN 2012102805063A CN 201210280506 A CN201210280506 A CN 201210280506A CN 102784129 A CN102784129 A CN 102784129A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- powder
- traditional chinese
- mixed
- preparation technology
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a preparation process of a traditional Chinese medicine plaster. The preparation process mainly comprises the following steps of: condensing single traditional Chinese medicines by a spray-drying method and extracting condensed traditional Chinese medicine powder; mixing the extracted condensed traditional Chinese medicine powder, adding ethanol into the mixture so as to uniformly dissolve the mixture, standing for 20-24 hours and then extracting a medicine solution; adding active carbon micropowder into the extracted medicine solution; and after the effective constituents of the medicine solution are fully absorbed, drying so as to obtain dried traditional Chinese medicine mixed powder, and the like. The preparation process can be used for greatly reducing the loss rate of effective constituents of the plaster; and the prepared traditional Chinese medicine plaster can release the effective constituents on the premise of lowering the medicine amount, the release rate is 200% higher than that of the traditional black plaster, and the disease treatment effect is improved.
Description
Technical field
The present invention relates to a kind of preparation technology, specifically be meant a kind of preparation technology of Chinese medicine patch unguentum.
Background technology
Traditional black plaster is historical in existing 1600 years of development of China, and outstanding contribution is being arranged aspect the human inner disease outer treat.Yet its production technology that falls behind not only has bigger infringement to operator's health, environment is had bigger pollution, and when high temperature is fried, also can destroys and lose Effective Components of Chinese Herb, even also can cause the human body lead poisoning.Simultaneously, because when adopting traditional approach to prepare plaster, its Effective Components of Chinese Herb is quantitatively inaccurate, disposable dosage is unstable, has therefore also caused the effective time of medicine shorter, and natural permeable property is poor, thick, big, hard, waits many defectives.
Summary of the invention
Defectives such as the production technology when the objective of the invention is to overcome present making plaster falls behind, and its EDD is short, natural permeable is poor, thick, hard provide a kind of preparation technology of brand-new Chinese medicine patch unguentum.
The present invention realizes through following technical scheme: a kind of preparation technology of Chinese medicine patch unguentum mainly may further comprise the steps:
(1) through spray drying method single medicinal material is concentrated, extract its concentrated traditional Chinese medicine powder;
(2) the concentrated traditional Chinese medicine powder of mixed extraction, and add ethanol to it and dissolve mixing, and leave standstill after 20～24 hours and extract drug solns;
(3) in the drug solns that extracts, add the active carbon micropowder of whole drug solns quality 15%～20%, carry out drying after treating fully to absorb the effective ingredient of drug solns, obtain the dry traditional Chinese medicine mixed-powder;
(4) in the Chinese medicine mixed-powder, add mixed function powder and stirring, and add the macromolecule adhesive and carry out secondary stirring, form subsequent use ointment;
(5) subsequent use ointment is coated on the non-woven fabrics uniformly, and compression molding behind the covering adherent layer;
(6) cut at last, check and pack.
Further, the mixed function powder described in the step (4) is that 20% magnetic functional powders, 5% far infrared heating powder and 5% negative-ion energy powder mixes form by mass percent.
In order to realize the present invention preferably, said concentration of ethanol is 90%, and described adhesive is a sodium polyacrylate.
Simultaneously, " the concentrated traditional Chinese medicine powder of mixed extraction, and add ethanol to it dissolve mixing " described in the step (2) is meant that be to carry out mixed dissolution at 1: 5 with concentrated traditional Chinese medicine powder and ethanol by mass ratio.
The present invention compares than prior art, has the following advantages and beneficial effect:
(1) the whole preparation technology of the present invention is simple, and low preparation cost can be applicable to that the plaster of various compositions is made.
(2) the present invention can reduce plaster loss of active ingredients rate greatly, can under the prerequisite that reduces dose, discharge effective ingredient fully, and is higher by 200% than traditional black plaster, improves the effect to disease treatment.
(3) the present invention does not have the cream of leakage phenomenon, and no organic solution is leaked, and compliance with environmental protection requirements had both been protected the healthy of operator, and big social benefit of tool and economic benefit are arranged again.
(4) ointment that adopts the present invention to prepare, its drug loading is big, the big characteristics of survival dose in being fit to.
(5) adopt the prepared ointment of preparation technology of the present invention, not only its moisture retention is strong, good with the compatibility of skin, and its affinity and breathability are all very good, are pasting comfortable.
(6) adopt the prepared ointment of preparation technology of the present invention, it has resistance to ag(e)ing preferably, can take off subsides repeatedly, and can also end administration at any time, and its medication is as safe as a house reliable.
(7) zest of the present invention and anaphylaxis are little, can increase patient's compliance, convenient treatment.
(8) not only consumption is accurate for preparation technology of the present invention, and area is fixed, and blood drug level is steady, and does not have peak valley phenomenon, can also effectively reduce toxic and side effects.
Description of drawings
Fig. 1 is a schematic flow sheet of the present invention.
The specific embodiment
Embodiment below in conjunction with concrete sets forth the present invention, but embodiment of the present invention is not limited thereto.
Embodiment 1
Adopt process of the present invention to prepare rheumatalgia relieving plaster:
Take by weighing Radix Aconiti 16g respectively, Radix Aconiti Kusnezoffii 16g, Radix Linderae 16g, Pseudobulbus Bletillae (Rhizoma Bletillae) 16g, Radix Angelicae Dahuricae 16g according to prescription; Radix Ampelopsis 16g, Eupolyphaga Seu Steleophaga 16g, Fructus Chaenomelis 16g, triangular 16g, Rhizoma Curcumae 16g; Radix Angelicae Sinensis 16g, Radix Paeoniae Rubra 16g, Cortex Cinnamomi 16g, Radix Et Rhizoma Rhei 32g, Fructus Forsythiae 12g; Sanguis Draxonis 10g, Olibanum 6g, (stir-fry) Myrrha 6g, Radix Notoginseng 6g, catechu 6g is subsequent use.
Its preparation process is:
(1) at first through spray drying method each flavor Chinese medicine is concentrated, extract its concentrated traditional Chinese medicine powder, promptly obtain Radix Aconiti respectively and concentrate powder, Radix Aconiti Kusnezoffii concentrates powder, and the Radix Linderae concentrates powder; Pseudobulbus Bletillae (Rhizoma Bletillae) concentrates powder, and the Radix Angelicae Dahuricae concentrates powder, and Radix Ampelopsis concentrates powder, and Eupolyphaga Seu Steleophaga concentrates powder; Fructus Chaenomelis concentrates powder, triangular concentrated powder, and Rhizoma Curcumae concentrates powder, and Radix Angelicae Sinensis concentrates powder; Radix Paeoniae Rubra concentrates powder, and Cortex Cinnamomi concentrates powder, and Radix Et Rhizoma Rhei concentrates powder, and Fructus Forsythiae concentrates powder; Sanguis Draxonis concentrates powder, and Olibanum concentrates powder, and (stir-fry) Myrrha concentrates powder, and Radix Notoginseng concentrates powder and catechu concentrates powder.
(2) these concentrated powder are fully mixed, and to add concentration to it be that 90% ethanol dissolves mixing, and leave standstill after 20～24 hours and extract drug solns, process relative density and be 1.05 fluid extract.
(3) in the drug solns that extracts, add the active carbon micropowder of whole drug solns quality 15%～20%, carry out drying after treating fully to absorb the effective ingredient of drug solns, obtain the dry traditional Chinese medicine mixed-powder.
(4) in the Chinese medicine mixed-powder, add mixed function powder and stirring, and add the macromolecule adhesive and carry out secondary stirring, form subsequent use ointment.In order to realize the present invention preferably, the adhesive here preferentially adopts sodium polyacrylate to realize.
(5) subsequent use ointment is coated on the non-woven fabrics uniformly, and compression molding behind the covering adherent layer.
(6) cut at last, check and pack and get final product.
The rheumatalgia relieving plaster that adopts this preparation technology to be made, its monolithic content of dispersion is 1.5G, volume is 7CM*10CM.
Embodiment 2
Adopt technology of the present invention to prepare the outer plaster of rhinitis:
Take by weighing Fructus Xanthii 15g according to prescription, Radix Angelicae Dahuricae 15g, Flos Magnoliae 15g, swimming sheet powder 3g, Herba Menthae 3g, Rhizoma Zingiberis Recens 5g is subsequent use.
Its preparation process is:
(1) at first through spray drying method each flavor Chinese medicine is concentrated, extract its concentrated traditional Chinese medicine powder, promptly obtain Fructus Xanthii respectively and concentrate powder, the Radix Angelicae Dahuricae concentrates powder, and Flos Magnoliae concentrates powder, and swimming sheet powder concentrates powder, and Herba Menthae concentrates powder, and Rhizoma Zingiberis Recens concentrates powder.
(2) these concentrated powder are fully mixed, and to add concentration to it be that 90% ethanol dissolves mixing, and leave standstill after 20～24 hours and extract drug solns, process relative density and be 1.05 fluid extract.
(3) in the drug solns that extracts, add the active carbon micropowder of whole drug solns quality 15%～20%, carry out drying after treating fully to absorb the effective ingredient of drug solns, obtain the dry traditional Chinese medicine mixed-powder.
(4) in the Chinese medicine mixed-powder, add mixed function powder and stirring, and add the macromolecule adhesive and carry out secondary stirring, form subsequent use ointment.In order to realize the present invention preferably, the adhesive here preferentially adopts sodium polyacrylate to realize.
(5) subsequent use ointment is coated on the non-woven fabrics uniformly, and compression molding behind the covering adherent layer.
(6) cut at last, check and pack and get final product.
Adopt the outer plaster of rhinitis of prepared of the present invention, its monolithic content of dispersion is 1.2G, and volume is 1.4*4CM.
Embodiment 3
Adopt technology of the present invention to prepare the outer plaster of flu:
Take by weighing according to prescription: Folium Perillae 10g, Herba Menthae 10g, Herba Pogostemonis 10g, windproof 10g, Herba Schizonepetae 10g, Flos Lonicerae 10g, Rhizoma Atractylodis 10g, Radix Astragali 10g and Radix Glycyrrhizae 3g.
Its preparation technology such as embodiment 1 and embodiment 2 are somebody's turn to do plaster outside the flu until generating.
Embodiment 4
Adopt technology of the present invention to prepare the outer plaster of hypertension:
Take by weighing according to prescription: Radix Salviae Miltiorrhizae 15g, Cortex Moutan 15g, Fructus Crataegi 15g, RADIX PUERARIAE 15g, Rhizoma Alismatis Radix Polygoni Multiflori 15g, each 15g of the Radix Astragali, Pheretima 5g, Fructus Schisandrae Chinensis 5g, Radix Paeoniae Rubra 5g, Rhizoma Chuanxiong 5g, Spica Prunellae 5g.
Its preparation technology such as embodiment 1 and embodiment 2, plaster outside generating this hypertension.
In sum, the present invention has quantitatively accurately through the pure concentrated traditional Chinese medicine powder that spray drying method extracts, and is prone to the advantage that is absorbed by acupuncture point meridian; And with the active carbon micropowder as high adsorbent, bank that then can play Effective Components of Chinese Herb and the effect of releasing control; And magnetic functional powders, far infrared heating powder and negative-ion energy powder can improve body local blood circulation and telangiectasis as physical penetration promoter, and to promoting active component, the Transdermal absorption of acupuncture point meridian plays the crux effect.
As stated, just can realize the present invention preferably.
Claims (5)
1. the preparation technology of a Chinese medicine patch unguentum is characterized in that, mainly may further comprise the steps:
(1) through spray drying method single medicinal material is concentrated, extract its concentrated traditional Chinese medicine powder;
(2) the concentrated traditional Chinese medicine powder of mixed extraction, and add ethanol to it and dissolve mixing, and leave standstill after 20～24 hours and extract drug solns;
(3) in the drug solns that extracts, add the active carbon micropowder of whole drug solns quality 15%～20%, carry out drying after treating fully to absorb the effective ingredient of drug solns, obtain the dry traditional Chinese medicine mixed-powder;
(4) in the Chinese medicine mixed-powder, add mixed function powder and stirring, and add the macromolecule adhesive and carry out secondary stirring, form subsequent use ointment;
(5) subsequent use ointment is coated on the non-woven fabrics uniformly, and compression molding behind the covering adherent layer;
(6) cut at last, check and pack.
2. the preparation technology of a kind of Chinese medicine patch unguentum according to claim 1 is characterized in that: the mixed function powder described in the step (4) is that 20% magnetic functional powders, 5% far infrared heating powder and 5% negative-ion energy powder mixes form by mass percent.
3. the preparation technology of a kind of Chinese medicine patch unguentum according to claim 1 and 2 is characterized in that: said concentration of ethanol is 90%.
4. according to the preparation technology of claim 2 or 3 described a kind of Chinese medicine patch unguentum, it is characterized in that: described adhesive is a sodium polyacrylate.
5. the preparation technology of a kind of Chinese medicine patch unguentum according to claim 4; It is characterized in that: " the concentrated traditional Chinese medicine powder of mixed extraction, and add ethanol to it dissolve mixing " described in the step (2) is meant that be to carry out mixed dissolution at 1: 5 with concentrated traditional Chinese medicine powder and ethanol by mass ratio.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102805063A CN102784129A (en) | 2012-08-08 | 2012-08-08 | Preparation process of traditional Chinese medicine plaster |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102805063A CN102784129A (en) | 2012-08-08 | 2012-08-08 | Preparation process of traditional Chinese medicine plaster |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102784129A true CN102784129A (en) | 2012-11-21 |
Family
ID=47149851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012102805063A Pending CN102784129A (en) | 2012-08-08 | 2012-08-08 | Preparation process of traditional Chinese medicine plaster |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102784129A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142904A (en) * | 2013-03-11 | 2013-06-12 | 高怀玉 | Traditional Chinese medicine for treating ecthyma leg |
| CN104547585A (en) * | 2015-01-15 | 2015-04-29 | 曾显美 | External traditional Chinese medicine composition and preparation for treating swelling and pain, cut wounds and skin ulcers |
| CN105641636A (en) * | 2014-10-28 | 2016-06-08 | 左英学 | Bitongling external ointment (external ointment for treating arthralgia) and preparation method thereof |
-
2012
- 2012-08-08 CN CN2012102805063A patent/CN102784129A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142904A (en) * | 2013-03-11 | 2013-06-12 | 高怀玉 | Traditional Chinese medicine for treating ecthyma leg |
| CN103142904B (en) * | 2013-03-11 | 2014-08-20 | 高怀玉 | Traditional Chinese medicine for treating ecthyma leg |
| CN105641636A (en) * | 2014-10-28 | 2016-06-08 | 左英学 | Bitongling external ointment (external ointment for treating arthralgia) and preparation method thereof |
| CN104547585A (en) * | 2015-01-15 | 2015-04-29 | 曾显美 | External traditional Chinese medicine composition and preparation for treating swelling and pain, cut wounds and skin ulcers |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2474314B1 (en) | Antiphlogistic, antioncotic and analgesic chinese herbal composition preparative method and usage thereof | |
| CN101987123B (en) | Medicament for easing pain of human body and preparation method thereof | |
| CN101987122B (en) | Medicament for easing pain of human body and preparation method thereof | |
| CN103768537B (en) | Traditional Chinese medicine composition for treating qi-stagnation and blood stasis type angina pectoris | |
| CN103705866A (en) | Traditional Chinese medicine composition for treating hypomenorrhea | |
| CN104161953A (en) | External-use traditional Chinese medicine liniment for treating rheumatoid bone diseases | |
| CN112843207A (en) | Formula and preparation method of smearing type thermal moxibustion ointment | |
| CN104784562B (en) | A kind of external used medicine for the treatment of breast carcinoma and preparation method thereof | |
| CN104258292A (en) | Drug for department of obstetrics and gynecology for treating pregnancy complication and manufacturing method thereof | |
| CN102784129A (en) | Preparation process of traditional Chinese medicine plaster | |
| CN103071120B (en) | Medicine for treating silicosis | |
| CN104399050A (en) | Traditional Chinese medicine for treating postpartum hemorrhage | |
| CN103989907A (en) | Traditional Chinese medicine composition for treating amyloidosis cutis | |
| CN101912567B (en) | Chinese medicinal prescription for treating chronic myocarditis | |
| CN104147526A (en) | Traditional Chinese medicine particles for treating icteric hepatitis and preparation method thereof | |
| CN103251800A (en) | Traditional Chinese medicine composition for treating allergic dermatitis | |
| CN105126022A (en) | Medicine for treating ichthyosis and preparation method of medicine | |
| CN104147490A (en) | Traditional Chinese medicine composition beneficial to fetus protection of livestock | |
| CN104474524A (en) | Traditional Chinese medicine composition for treating viral myocarditis | |
| AU2013101458A4 (en) | Pharmaceutical formulation for treating allergic rhinitis and preparation method thereof | |
| CN102038906A (en) | Medicament for treating psoriasis | |
| CN105521384A (en) | Gynecological medicine for treating pregnancy complications, and preparation method thereof | |
| CN102416160A (en) | Medicinal liquor for dispelling cold and warming body | |
| CN105396031A (en) | Traditional Chinese medicine composition for treating female irregular menstruation | |
| CN104510827A (en) | Traditional Chinese medicine for treating acne |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20121121 |