CN102727768A - Preparation method for Chinese herbal lotion used for treating hemorrhagic senile vaginitis - Google Patents

Preparation method for Chinese herbal lotion used for treating hemorrhagic senile vaginitis Download PDF

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CN102727768A
CN102727768A CN2012101985980A CN201210198598A CN102727768A CN 102727768 A CN102727768 A CN 102727768A CN 2012101985980 A CN2012101985980 A CN 2012101985980A CN 201210198598 A CN201210198598 A CN 201210198598A CN 102727768 A CN102727768 A CN 102727768A
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赵青
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Abstract

The invention provides a preparation method for a Chinese herbal lotion used for treating hemorrhagic senile vaginitis, which belongs to the technical field of preparation methods for traditional Chinese medicines. Conventionally, antibiotics and sulfonamides are generally used for treating hemorrhagic senile vaginitis, but antibiotics and sulfonamides have the disadvantage of great side effects. A technical scheme provided in the invention is as follows: the 31 medicines of camellia, osbeckia chinensis, hairyvein agrimony, pseudo-ginseng, garden burnet, pink reineckea herb, plant soot, furnace oil, human hair, Japanese dock root, ophicalcite, Chinese arborvitae twigs and leaves, madder root, common sage herb, white dead nettle, gromwell root, Japanese beauty-berry, sophora flower, solanum nigrum, Chinese gentian, Polygonum hydropiper, sugarcane, Hibiscus mutabilis flower, lightyellow sophora root, balsam pear, broadleaf holly leaves, Elephantopus scaber, gentrin knotweed, Saxifraga stolonifera, yerbadetajo herb and liquorice root are soaked in water and then decocted on a slow fire, dregs are filtered, and obtained decoction soup is the Chinese herbal lotion used for treating hemorrhagic senile vaginitis. The Chinese herbal lotion prepared in the invention has the advantages of small toxic and side effects, a short treatment course, a high cure rate and capacity of preventing adverse influence generated by western medicines.

Description

A kind of Chinese medicine lotion method for preparing of treating the bleeding type senile vaginitis
Technical field
The present invention relates to Chinese medicine lotion method for preparing technical field, is a kind of Chinese medicine lotion method for preparing of treating the bleeding type senile vaginitis more specifically.
Background technology
Treatment bleeding type senile vaginitis generally adopts antibiotics and sulfonamides at present.
1, carbenicillin: various types of allergy can occur.Can cause neural poison reaction, pulmonary edema after heavy dose of administration; Can occur transience ammonia enzyme during the medication raises and granulocytopenia.
2, cefoperazone: can there be pain the intramuscular injection part; Allergy such as accidental erythra, drug fever; Individual patients pancytopenia, can occur and cross property transaminase rising, prolonged prothrombin or hemorrhage etc.
3, aztreonam: idol has parageusia, erythra, slight gastrointestinal reaction, the intramuscular injection local pain, and phlebitis can appear in quiet notes.
4, adopt the sulfamethoxazole patient to cause gastrointestinal reaction, crystalluria, hematuria, erythra, medicine heat and leukopenia sometimes.
5, adopt penicillin: with before must do skin test, positive person is forbidden.(the most dangerous anaphylactic shock can occur in and do tuerculoderma at that time because penicillin is prone to take place allergy, particularly anaphylactic shock; Only a few can occur in the process of continuous use; The latter claims the Delayed Hypersensitivity shock), like untimely rescue, but threat to life.
6, ampicillin: a large amount of oral gastrointestinal upset that often occur.There is pain the intramuscular injection part.No matter oral or injection all can cause allergy, with erythra for seeing more.Must do skin test earlier before the medication.
7, use kanamycin: all toxic to acoustic nerve and kidney, the former shows as tinnitus, auditory dysesthesia even permanent deafness, and the latter shows as albuminuria, cylinderuria etc.
8, amoxicillin: accidental erythra, oral can have nauseating, epigastric discomfort, diarrhoea etc. after a large amount of; Pseudomembranous colitis.
Summary of the invention
For overcoming above shortcoming, the objective of the invention is to invent a kind of Chinese medicine lotion method for preparing of treating the bleeding type senile vaginitis.Colpitis mycotica is that the Candida albicans by dark mould Pseudomonas causes.Be more common in anemia of pregnant woman or diabetics, prolonged application antibiotics also is prone to take place.
Etiology and pathogenesis: because old, QI-blood circulation is not smooth, QI failing to control blood.Adding is menopause or the women that excision bilateral ovaries history is arranged again, the ovarian function decline, and the vagina self-cleaning action reduces, and antibacterial is easy to infect, and causes primary disease.
Clinical manifestation: vaginal secretions is mixed with blood.The performance leucorrhoea grow in quantity, yellow skin is white, and matter is thin, is mixed with blood sometimes.Intravaginal and urethral orifice burn sense of discomfort.During gynecologial examination, find vaginal mucosa atrophy attenuation, rubescent, often can see the little petechia that is dispersed in, sometimes aphtha can be arranged.Body of the tongue is light red, yellow and thin fur, rapid pulse.
Its technical scheme does: get Flos Camelliae Japonicae 6 weight portions, Herba Osbeckiae 15 weight portions, Herba Agrimoniae 10 weight portions, Radix Notoginseng 3 weight portions, Radix Sanguisorbae 6 weight portions, Herba Reineckeae Carneae 9 weight portions, Pulvis Fumi Carbonisatus 6 weight portions, Terra Flava Usta 9 weight portions, Crinis Carbonisatus 3 weight portions, Radix Rumicis Japonici 3 weight portions, Ophicalcitum 9 weight portions, Cacumen Platycladi 3 weight portions, Radix Rubiae 6 weight portions, Herba Salviae Plebeiae 9 weight portions, Herba lamii barbati 6 weight portions, Radix Arnebiae (Radix Lithospermi) 9 weight portions, Folium Callicarpae Formosanae 6 weight portions, Flos Sophorae 6 weight portions, Herba Solani Nigri 15 weight portions, Radix Gentianae 3 weight portions, Herba Polygoni hydropiperis 15 weight portions, Caulis Sacchari sinensis 60 weight portions, Flos Hibisci Mutabilis 6 weight portions, Radix Sophorae Flavescentis 6 weight portions, Fructus Momordicae charantiae 3 weight portions, Folium Ilicis 6 weight portions, Herba Elephantopi scaberis 9 weight portions, Rhizoma Polygoni Cuspidati 9 weight portions, Herba Saxifragae 9 weight portions, Herba Ecliptae 9 weight portions and Radix Glycyrrhizae 9 weight portions; Above 31 flavor medicines are put into 1800 ml waters; Soaked 35 minutes; Slow fire is fried 35 minutes then; Filter and remove residue is total to 390 milliliters of fried medicinal liquids, and fried medicinal liquid is the Chinese medicine lotion of treatment bleeding type senile vaginitis.
The advantage of this invention is: this Chinese medicine is made simple, and the herbal toxic effect of processing is little, short treating period, and cure rate is high.Can also avoid using the untoward reaction that Western medicine produces.Flos Camelliae Japonicae, Herba Osbeckiae, Herba Agrimoniae, Radix Notoginseng, Radix Sanguisorbae, Herba Reineckeae Carneae, Pulvis Fumi Carbonisatus, Terra Flava Usta, Crinis Carbonisatus, Radix Rumicis Japonici, Ophicalcitum, Cacumen Platycladi, Radix Rubiae, Herba Salviae Plebeiae, Herba lamii barbati, Radix Arnebiae (Radix Lithospermi), Folium Callicarpae Formosanae, Flos Sophorae, more than 18 flavor medical instruments cooling blood for improving eyesight, hemostasis with astringents are arranged, the effect of the chest stuffiness relieving of regulating the flow of vital energy, heat-clearing and toxic substances removing.In the process of treatment bleeding type senile vaginitis, play main therapeutical effect, so be monarch drug.Herba Solani Nigri, Radix Gentianae, Herba Polygoni hydropiperis, Caulis Sacchari sinensis, Flos Hibisci Mutabilis, Radix Sophorae Flavescentis, Fructus Momordicae charantiae, Folium Ilicis, Herba Elephantopi scaberis, Rhizoma Polygoni Cuspidati, Herba Saxifragae.More than 11 flavor medical instruments heat clearing and damp drying, wind dispelling insecticide, clearing away heat and promoting diuresis are arranged, clear away heart-fire make eye bright, clearing away summer-heat, clearing away heat to dispel wind, clearing away heat and promoting production of body fluid, heat clearing away removing food stagnancy, removing heat from blood, diuretic, reduce phlegm give birth to cough, the effect of removing toxic substances and promoting subsidence of swelling.In the process of treatment bleeding type senile vaginitis, can assist principal agent performance therapeutical effect, so be ministerial drug.Herba Ecliptae: sweet, sour, cold.Go into liver, kidney, stomach, the large and small intestinal Five Classics.Cooling blood for hemostasis, yin nourishing black hair, removing dampness to relieve itching.Because of it can lead the through focus performance of all medicines therapeutical effect, so be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.The bias of all medicines can be entangled, the toxicity of all medicines can be alleviated again, so be messenger drug.Camellia, osbeckia chinensis, hairyvein agrimony, pseudo-ginseng, garden burnet, pink reineckea herb, Plant Soot, humus flava usta, blood are surplus, sheep hoof, marmor serpentinatum, cacumen biotae, madder, Common Sage Herb, white dead nettle, Asian puccoon, Japanses beauty-berry, sophora flower, black nightshade, rough gentian, water pepper, sugarcane, cottonrose hibiscus flower, kuh-seng, balsam pear, bitter leaves tea, bitter ground courage, giant knotweed, kiss-me, eclipta, Radix Glycyrrhizae, more than 31 medical instruments cooling blood and hemostasis arranged, promote the production of body fluid to quench thirst, enriching yin heat extraction, activating QI to alleviate the depression, promoting blood circulation and stopping pain, go stasis of blood pain relieving, the blood that looses broken disease, blood stasis removing analgesic, the effect of moisturizing laxation.It is the optimum formula of treatment bleeding type senile vaginitis.Flos Camelliae Japonicae: sweet, bitter, hot, cold.Go into liver, lung, large intestine three warps.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, skin ulcer is treated in detoxifcation.Herba Osbeckiae: suffering, flat.Go into lung, large intestine, liver three warps.The hemostasis repercussive, clearing away heat and eliminating dampness, relieving cough and asthma, blood stasis dispelling dispels the wind.Herba Agrimoniae: bitter, puckery, little sweet, flat.Go into lung, liver, spleen, large intestine four warps.Astringing to arrest bleeding, tonify deficiency dysentery relieving, parasite killing detoxifcation, preventing the attack (or recurrence) of malaria, promoting blood circulation and detumescence.Radix Notoginseng: sweet, little hardship, temperature, nontoxic.Go into liver, stomach, large intestine three warps.The hemostasis dissipating blood stasis, promoting blood circulation and detumescence, eliminating stasis to stop pain.Radix Sanguisorbae: bitter, sour, cold.Go into lung, kidney two warps.Cooling blood for hemostasis.Herba Reineckeae Carneae: sweet, hot, flat, cool.Go into lung, stomach, liver, large intestine four warps.Clearing away lung-heat to relieve cough, cooling blood for hemostasis, heat-clearing and toxic substances removing.Pulvis Fumi Carbonisatus: hot, bitter, temperature.Go into lung, stomach, liver, kidney four warps.Hemostasis, removing food stagnancy dysentery relieving, heat-clearing and toxic substances removing.Terra Flava Usta: suffering, tepor.Go into spleen, stomach, liver three warps.Warming middle-JIAO hemostasis, stomach function regulating preventing or arresting vomiting, warming the spleen astringing intestine to stop diarrhea.Crinis Carbonisatus: hardship, flat.Go into liver, stomach two warps.Hemostasis dissipating blood stasis, nourishing YIN diuresis, promoting tissue regeneration and ulcer healing.Radix Rumicis Japonici: hardship, cold, mild toxicity.Go into spleen, liver, large intestine, bladder four warps.Cooling blood for hemostasis, parasite killing are treated tinea, expelling pathogenic heat to loosen the bowels.Ophicalcitum: sour, puckery, flat.Go into Liver Channel.Astringing to arrest bleeding, hemostasis by removing blood stasis.Cacumen Platycladi: bitter, puckery, be slightly cold.Go into lung, the heart, liver, large intestine four warps.Cooling blood for hemostasis, clearing and antitussive, expelling wind and removing dampness, diffusing toxic swelling, growing and blacking hair.Radix Rubiae: bitter, salty, sour, cold.Go into liver, the heart, spleen, stomach, the lung Five Classics.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, dispelling wind collateral dredging, heat clearing away jaundice eliminating, eliminating phlegm and stopping cough.Herba Salviae Plebeiae: hot, bitter, cold.Go into the heart, liver, kidney three warps.Cooling blood for hemostasis, inducing diuresis to remove edema, detoxifcation parasite killing.Herba lamii barbati: little sweet, flat.Go into lung, kidney two warps.Cooling blood for hemostasis, inducing diuresis for treating stranguria syndrome, eliminating dampness by diuresis band, dissipating blood stasis for subsidence of swelling.Radix Arnebiae (Radix Lithospermi): bitter, salty, cold.Go into the heart, percardium, liver, small intestinal four warps.Cooling blood for hemostasis, heat-clearing and toxic substances removing, clearing away heat-damp and promoting diuresis, let out fiery relieving constipation.Folium Callicarpae Formosanae: bitter, puckery, cold.Go into liver, spleen two warps.Hemostasis with astringents, heat-clearing and toxic substances removing.Flos Sophorae: hardship is slightly cold.Go into lung, large intestine two warps.Cooling blood for hemostasis, liver heat removing pathogenic fire reducing, parasite killing are treated skin ulcer.Herba Solani Nigri: bitter, little sweet, cold; Slightly poisonous.Go into lung, liver, stomach three warps.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence, the spasmolytic of reducing phlegm, liver heat removing and eyesight improving.Radix Gentianae: hardship, cold.Go into liver, gallbladder, stomach three warps.Heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire, the pathogenic fire purging arresting convulsion is good for the stomach.Herba Polygoni hydropiperis: suffering, temperature.Go into heart channel.Eliminating dampness to stop diarrhea, eliminating stasis to stop pain, removing toxic substances and promoting subsidence of swelling, parasite killing is treated skin ulcer.Caulis Sacchari sinensis: sweet, cold, nontoxic.Go into lung, spleen, stomach three warps.Clearing heat and relieving fidgetness, promoting the production of body fluid to quench thirst and in moisturize, relieving cough and moistening lung relieves the effect of alcohol and refreshes oneself, and controls the preventing or arresting vomiting of choking.Flos Hibisci Mutabilis: hot, bitter, sweet, flat.Go into liver, lung two warps.Heat-clearing and toxic substances removing, cooling blood for hemostasis, reducing swelling and alleviating pain.Radix Sophorae Flavescentis: hardship, cold, slightly poisonous.Go into the heart, liver, stomach, large intestine, small intestinal, bladder the six channels.Heat clearing and damp drying, wind dispelling insecticide, clearing away heat and promoting diuresis, hemostasis and dysentery-stopping.Fructus Momordicae charantiae: hardship, cold.Go into liver, the heart, lung three warps.Heat clearing away washs summer-heat, clear away heart-fire make eye bright, clearing away summer-heat.Folium Ilicis: bitter, sweet, Great Cold.Go into liver, lung, stomach three warps.Clearing away heat to dispel wind, clearing away heat and promoting production of body fluid, clearing away heat to cure dysentery, heat clearing away removing food stagnancy.Herba Elephantopi scaberis: bitter, hot, cold.Go into lung, liver, spleen three warps.Heat clearing and damp drying, removing heat from blood, heat-clearing and toxic substances removing, diuretic.Rhizoma Polygoni Cuspidati: hardship is slightly cold.Go into liver, gallbladder, lung three warps.Activating blood circulation and dissipating phlegm, clearing away heat-damp and promoting diuresis, reduce phlegm and give birth to cough, detoxify pain relieving, cooling blood for hemostasis, purging heat to relax the bowels.Herba Saxifragae: little hardship, suffering, cold, slightly poisonous.Go into lung, spleen, large intestine three warps.Expelling wind and clearing away heat, removing toxic substances and promoting subsidence of swelling, cooling blood for hemostasis.Herba Ecliptae: sweet, sour, cold.Go into liver, kidney, stomach, the large and small intestinal Five Classics.Cooling blood for hemostasis, yin nourishing black hair, removing dampness to relieve itching.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.
The specific embodiment
Get Flos Camelliae Japonicae 6g, Herba Osbeckiae 15g, Herba Agrimoniae 10g, Radix Notoginseng 3g, Radix Sanguisorbae 6g, Herba Reineckeae Carneae 9g, Pulvis Fumi Carbonisatus 6g, Terra Flava Usta 9g, Crinis Carbonisatus 3g, Radix Rumicis Japonici 3g, Ophicalcitum 9g, Cacumen Platycladi 3g, Radix Rubiae 6g, Herba Salviae Plebeiae 9g, Herba lamii barbati 6g, Radix Arnebiae (Radix Lithospermi) 9g, Folium Callicarpae Formosanae 6g, Flos Sophorae 6g, Herba Solani Nigri 15g, Radix Gentianae 3g, Herba Polygoni hydropiperis 15g, Caulis Sacchari sinensis 60g, Flos Hibisci Mutabilis 6g, Radix Sophorae Flavescentis 6 g, Fructus Momordicae charantiae 3g, Folium Ilicis 6g, Herba Elephantopi scaberis 9g, Rhizoma Polygoni Cuspidati 9g, Herba Saxifragae 9g, Herba Ecliptae 9g and Radix Glycyrrhizae 9g; Above 31 flavor medicines are put into 1800 ml waters; Soaked 35 minutes; Slow fire is fried 35 minutes then; Filter and remove residue, fried medicinal liquid are the Chinese medicine lotion of treatment bleeding type senile vaginitis.Fried medicinal liquid is 390 milliliters altogether, and when the patient of bleeding type senile vaginitis need treat, making fluid temperature was 35 ℃, and each 130 milliliters, the washout affected part, three times on the one, two is a course of treatment, if symptom is still deposited, washes for second course of treatment again, so that recovery from illness.
Bleeding type senile vaginitis patient is totally 381 examples
The range of age of table one, 381 routine bleeding type senile vaginitis patients
Age (year) 46~48 49~50 51~53 54~56
The example number 11 252 115 3
Percentage ratio 2.9% 66.1% 30.2% 0.8%
Table two, 381 routine bleeding type senile vaginitis patients' curative effect table
Curative effect Cure Take a turn for the better Invalid
The example number 379 2 Do not have
Percentage ratio 99.5% 0.5% Do not have
Table three, 381 routine bleeding type senile vaginitis patients show the course of treatment
The treatment natural law 3~5 6~9 10~14 15~20
The example number 12 231 131 7
Percentage ratio 3.2% 60.6% 34.4% 1.8%
Information slip before and after table four, the 381 routine bleeding type senile vaginitis patient
Figure 20121019859801000021

Claims (1)

1. Chinese medicine lotion method for preparing of treating the bleeding type senile vaginitis; It is characterized in that: get Flos Camelliae Japonicae 6 gram, Herba Osbeckiae 15 grams, Herba Agrimoniae 10 grams, Radix Notoginseng 3 grams, Radix Sanguisorbae 6 grams, Herba Reineckeae Carneae 9 grams, Pulvis Fumi Carbonisatus 6 grams, Terra Flava Usta 9 grams, Crinis Carbonisatus 3 grams, Radix Rumicis Japonici 3 grams, Ophicalcitum 9 grams, Cacumen Platycladi 3 grams, Radix Rubiae 6 grams, Herba Salviae Plebeiae 9 grams, Herba lamii barbati 6 grams, Radix Arnebiae (Radix Lithospermi) 9 grams, Folium Callicarpae Formosanae 6 grams, Flos Sophorae 6 grams, Herba Solani Nigri 15 grams, Radix Gentianae 3 grams, Herba Polygoni hydropiperis 15 grams, Caulis Sacchari sinensis 60 grams, Flos Hibisci Mutabilis 6 grams, Radix Sophorae Flavescentis 6 grams, Fructus Momordicae charantiae 3 grams, Folium Ilicis 6 gram, Herba Elephantopi scaberis 9 gram, Rhizoma Polygoni Cuspidati 9 gram, Herba Saxifragae 9 gram, Herba Ecliptae 9 gram and Radix Glycyrrhizae 9 gram; Above 31 flavor medicines are put into 1800 ml waters; Soaked 35 minutes; Slow fire is fried 35 minutes then; Filter and remove residue is total to 390 milliliters of fried medicinal liquids, and fried medicinal liquid is the Chinese medicine lotion of treatment bleeding type senile vaginitis.
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103110785A (en) * 2013-02-09 2013-05-22 李坚恩 Preparation method of traditional Chinese medicine for treating blood-heat type subconjunctival hemorrhage
CN103110786A (en) * 2013-02-09 2013-05-22 王维萌 Preparation method of traditional Chinese medicine for treating traumatic type subconjunctival hemorrhage
CN103110790A (en) * 2013-02-09 2013-05-22 李坚恩 Preparation method of traditional Chinese medicine chest distress type subconjunctival hemorrhage
CN103110784A (en) * 2013-02-09 2013-05-22 赵相兰 Preparation method of traditional Chinese medicine for treating liver depression forming fire type scleritis
CN103494958A (en) * 2013-09-27 2014-01-08 周莉 Traditional Chinese medicine lotion for treating gynecological inflammations as well as preparation method thereof
CN104623043A (en) * 2015-01-30 2015-05-20 郭秀荣 Traditional Chinese medicine capable of treating senile vaginitis
CN110997075A (en) * 2017-08-17 2020-04-10 荷兰联合利华有限公司 Topical compositions for enhancing barrier function

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CN101269192A (en) * 2007-03-20 2008-09-24 谢晓涛 Chinese medicinal composition for treating gynaecologic inflammation and preparation thereof
CN101361848A (en) * 2008-09-28 2009-02-11 崔平田 Vaginitis treating medicine
CN101612343A (en) * 2009-07-28 2009-12-30 杭州普瑞美克生物科技有限公司 A kind of washing liquid for the treatment of female vagina inflammation

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* Cited by examiner, † Cited by third party
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CN101269192A (en) * 2007-03-20 2008-09-24 谢晓涛 Chinese medicinal composition for treating gynaecologic inflammation and preparation thereof
CN101167894A (en) * 2007-11-09 2008-04-30 北京中科雍和医药技术有限公司 Traditional Chinese medicinal washing lotion for treating dermatitis, vulvitis and vaginitis
CN101361848A (en) * 2008-09-28 2009-02-11 崔平田 Vaginitis treating medicine
CN101612343A (en) * 2009-07-28 2009-12-30 杭州普瑞美克生物科技有限公司 A kind of washing liquid for the treatment of female vagina inflammation

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103110785A (en) * 2013-02-09 2013-05-22 李坚恩 Preparation method of traditional Chinese medicine for treating blood-heat type subconjunctival hemorrhage
CN103110786A (en) * 2013-02-09 2013-05-22 王维萌 Preparation method of traditional Chinese medicine for treating traumatic type subconjunctival hemorrhage
CN103110790A (en) * 2013-02-09 2013-05-22 李坚恩 Preparation method of traditional Chinese medicine chest distress type subconjunctival hemorrhage
CN103110784A (en) * 2013-02-09 2013-05-22 赵相兰 Preparation method of traditional Chinese medicine for treating liver depression forming fire type scleritis
CN103494958A (en) * 2013-09-27 2014-01-08 周莉 Traditional Chinese medicine lotion for treating gynecological inflammations as well as preparation method thereof
CN103494958B (en) * 2013-09-27 2015-04-22 周莉 Traditional Chinese medicine lotion for treating gynecological inflammations as well as preparation method thereof
CN104623043A (en) * 2015-01-30 2015-05-20 郭秀荣 Traditional Chinese medicine capable of treating senile vaginitis
CN110997075A (en) * 2017-08-17 2020-04-10 荷兰联合利华有限公司 Topical compositions for enhancing barrier function

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