CN102727206B - Brain, carotid artery and aorta three-in-one scanning method and scanning system - Google Patents
Brain, carotid artery and aorta three-in-one scanning method and scanning system Download PDFInfo
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- CN102727206B CN102727206B CN201210176865.4A CN201210176865A CN102727206B CN 102727206 B CN102727206 B CN 102727206B CN 201210176865 A CN201210176865 A CN 201210176865A CN 102727206 B CN102727206 B CN 102727206B
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- 210000000709 aorta Anatomy 0.000 title claims abstract description 40
- 210000004556 brain Anatomy 0.000 title claims abstract description 34
- 210000001715 carotid artery Anatomy 0.000 title claims abstract description 34
- 238000000034 method Methods 0.000 title claims abstract description 14
- 238000003384 imaging method Methods 0.000 claims abstract description 82
- 238000002595 magnetic resonance imaging Methods 0.000 claims abstract description 15
- 239000008280 blood Substances 0.000 claims description 19
- 210000004369 blood Anatomy 0.000 claims description 19
- 230000005415 magnetization Effects 0.000 claims description 9
- 238000002601 radiography Methods 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 230000001960 triggered effect Effects 0.000 claims description 6
- 238000005516 engineering process Methods 0.000 description 5
- 238000002075 inversion recovery Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 3
- 238000012935 Averaging Methods 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 210000004004 carotid artery internal Anatomy 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 238000009795 derivation Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002592 echocardiography Methods 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
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Abstract
The invention relates to a brain, carotid artery and aorta three-in-one scanning method, comprising the following steps of: positioning a scanning part; scanning a brain by utilizing parallel imaging of three-dimensional magnetic resonance imaging; scanning a carotid artery by utilizing the three-dimensional magnetic resonance imaging and collecting a T1 weighted three-dimensional rapid spin echo imaged image, a T2 weighted three-dimensional rapid spin echo imaged image and a radiographed T1 weighted three-dimensional rapid spin echo image; and scanning a carotid artery by utilizing T1 weighted three-dimensional rapid spin echo imaging and T2 weighted three-dimensional rapid spin echo imaging which are combined. The brain, carotid artery and aorta three-in-one scanning method and system disclosed by the invention firstly adopt the steps of firstly positioning the scanning part and directly scanning the brain, the carotid artery and the aorta; the positioning and the scanning do not need to be repeated so that the scanning time is shortened; the brain is scanned by using a rapid imaging method by parallel imaging so that the scanning time is reduced; and three-dimensional T1 weighted imaging and two-dimensional T2 weighted imaging are combined to scan the carotid artery so that the scanning time is further shortened.
Description
[technical field]
The present invention relates to biomedical sector, particularly a kind of cranium brain, carotid artery and the Trinitarian scan method of aorta and scanning system.
[background technology]
Clinical research finds, in the infantile metopism brain, in carotid artery and in aorta the composition of speckle contribute to the diagnosis of cerebrovascular disease.In order to understand the speckle situation of three inside, need respectively it to be carried out to imaging inspection.
Traditional method is to adopt MRI(Magnetic Resonance Imaging, nuclear magnetic resonance) check cranium brain, internal carotid artery and aorta, need respectively about half an hour, they are combined, need to spend the sweep time of 1.5 hours to 2 hours, so limited the application clinically of MRI technology long sweep time.
[summary of the invention]
Based on this, be necessary to provide a kind of Trinitarian scan method of cranium brain, carotid artery and aorta that can shorten sweep time.
In addition, also be necessary to provide a kind of Trinitarian scanning system of cranium brain, carotid artery and aorta that can shorten sweep time.
A kind of cranium brain, carotid artery and the Trinitarian scan method of aorta comprise the following steps:
The location scanning position;
Adopt the parallel imaging mode in the Three-Dimensional Magnetic resonance image-forming to scan the cranium brain;
Adopt three-dimensional MRI scan carotid artery, gather image, the image of T2 weighting 3-dimensional fast spin echo imaging and the T1 weighting 3-dimensional fast spin echo image after radiography of T1 weighting 3-dimensional fast spin echo imaging;
Adopt T1 weighting 3-dimensional fast spin echo imaging and the two-dimentional T2 weighting quick spin echo imaging scanning aorta that combines.
Preferably, described parallel imaging mode can be one or more combinations in the imaging of T1 weighting 3-dimensional fast spin echo, T2 weighting 3-dimensional fast spin echo imaging and the imaging of three-dimensional intensity of magnetization preparation gradin-echo.
Preferably, described employing T1 weighting 3-dimensional fast spin echo imaging and two-dimentional T2 weighting quick spin echo imaging combine scanning aortal step comprise:
Adopt speckle and speckle position in T1 weighting 3-dimensional fast spin echo image scanning aorta, and measure the size of speckle;
Adopt the black blood interlacing fast acquisition interleaved spin echo of two-dimentional T2 weighting multilamellar to gather image on described speckle position;
3-D view registration by the two dimensional image of T2 weighting and T1 weighting.
Preferably, the black blood interlacing sequence of described two-dimentional T2 weighting multilamellar is by electrocardiogram triggered, and the aortal cycle of described scanning is heart beat cycle.
A kind of cranium brain, carotid artery and the Trinitarian scanning system of aorta comprise:
Locating module, for the location scanning position;
Scan module, for adopting the parallel imaging mode of Three-Dimensional Magnetic resonance image-forming to scan the cranium brain, adopt three-dimensional MRI scan carotid artery, gather image, the image of T2 weighting 3-dimensional fast spin echo imaging and the T1 weighting 3-dimensional fast spin echo image after radiography of the imaging of T1 weighting 3-dimensional fast spin echo, and adopt T1 weighting 3-dimensional fast spin echo imaging and the two-dimentional T2 weighting quick spin echo imaging scanning aorta that combines.
Preferably, described parallel imaging mode can be one or more combinations in the imaging of T1 weighting 3-dimensional fast spin echo, T2 weighting 3-dimensional fast spin echo imaging and the imaging of three-dimensional intensity of magnetization preparation gradin-echo.
Preferably, described scan module comprises:
Detecting unit, adopt speckle and speckle position in T1 weighting 3-dimensional fast spin echo image scanning aorta, and measure the size of speckle;
Collecting unit gathers image for adopting the black blood interlacing fast acquisition interleaved spin echo of two-dimentional T2 weighting multilamellar on described speckle position;
Registration unit, for the 3-D view registration of the two dimensional image by the T2 weighting and T1 weighting.
Preferably, the black blood interlacing fast acquisition interleaved spin echo of described two-dimentional T2 weighting multilamellar is by electrocardiogram triggered, and the aortal cycle of described scanning is heart beat cycle.
Above-mentioned cranium brain, carotid artery and the Trinitarian scan method of aorta and system, adopt at first location scanning position, behind location, directly scanning cranium brain, carotid artery and aorta, do not need resetting scanning, shortened sweep time, and adopt the fast imaging method scanning cranium brains such as parallel imaging, reduce sweep time, adopted three-dimensional T1 weighted imaging and two-dimentional T2 weighting quick spin echo imaging in conjunction with the scanning aorta, further shortened sweep time.
[accompanying drawing explanation]
Fig. 1 is the schematic flow sheet of cranium brain, carotid artery and the Trinitarian scan method of aorta in one embodiment;
The sequential chart that Fig. 2 is the variable deflection angle of SPACE sequence;
The schematic flow sheet that Fig. 3 is step S40;
Fig. 4 is the black blood interlacing fast acquisition interleaved spin echo figure of two-dimentional T2 weighting multilamellar;
Fig. 5 is the internal structure schematic diagram of cranium brain, carotid artery and the Trinitarian scanning system of aorta in one embodiment;
The internal structure schematic diagram that Fig. 6 is scan module.
[specific embodiment]
Below in conjunction with specific embodiment and accompanying drawing, technical scheme is described in detail.
As shown in Figure 1, in one embodiment, a kind of cranium brain, carotid artery and the Trinitarian scan method of aorta comprise the following steps:
Step S10, the location scanning position.
Concrete, for the patient is with upper head and neck radio-frequency coil and heart coil, adopt the localizer location scanning, obtain the location scanning position, do not need to repeat location scanning so that follow-up, save positioning time.
Step S20, adopt the parallel imaging mode in the Three-Dimensional Magnetic resonance image-forming to scan the cranium brain.
Concrete, the parallel imaging mode can be one or more combinations in T1 weighting 3-dimensional fast spin echo imaging (T1-SPACE), T2 weighting 3-dimensional fast spin echo imaging (T2-SPACE) and the imaging of three-dimensional intensity of magnetization preparation gradin-echo (MPRAGE).
Wherein, the T1 weighted imaging is given prominence to tissue T 1 relaxation (longitudinal relaxation) difference, and the T2 weighted imaging is given prominence to tissue T 2 relaxation (transverse relaxation) difference.
SPACE(Sampling perfection with application-optimized contrasts by using different flip angle evolution, the 3-dimensional fast spin echo imaging) technology by being used the design of variable deflection angle (variable flip angle) in returning poly-pulse, can solve echo train falls short of and the very high problem of radio frequency absorption rate (Specific Absorption Rate, SAR).The SPACE technology has following characteristics:
(1) based on TSE(Turbo Spin Echo, fast spin echo) imaging technique, once excite, gather a plurality of echoes, obtain the TSE contrast.
(2) adopt the overlength echo train collection of variable flip angle, according to the ultimate principle of magnetic resonance signal derivation, optimize change deflection angle pattern and can overcome the T2 attenuation effect, the blurring effect of avoiding the long echo chain to bring, and returning poly-pulse is no longer wide-angle, SAR also obviously reduces.
(3) SPACE is for the proton density contrast, and T2 and T1 contrast have designed the variable inverted pattern of Different Optimization.
(4) SPACE has optimized the design of sequence, for example adopts the pulsus durus punching as returning poly-pulse, and echo sounding is very short, in the identical time, allows to gather more data.
Figure 2 shows that the sequential chart of the variable deflection angle of SPACE sequence, in figure, α
1and α
2for variable deflection angle, RF is radio-frequency pulse, ESP
1refer to the echo separation of first 180 ° of pulses, ESP
2refer to that back becomes the echo separation of deflection angle, G
srefer to zone selection gradient (section-select gradient).
Three-dimensional intensity of magnetization preparation gradin-echo (MPRAGE) refers to application 180 degree reverse radio-frequency pulses outside the data acquisition forehead, subsequence excites and the gradin-echo three dimensional fourier transform by little flip angle (5 degree are to 10 degree), makes the saturation effect minimum and produces enough cross magnetization intensity.This 180 degree reverse radio-frequency pulse is level selection, be similar to inversion recovery technology, magnetization vector in the whole transmitting coil of alternative upset, handle Mz, produce tissue T 1 weighting contrast in time delay between inversion pulse and data acquisition, this pulse train is pressed the three dimensional constitution collection, can obtain best room and time resolution.
In the present embodiment, adopt the Three-Dimensional Magnetic resonance image-forming can improve signal noise ratio (snr) of image, adopt the parallel imaging mode to reduce sweep time.
Step S30, adopt three-dimensional MRI scan carotid artery, gathers image, the image of T2 weighting 3-dimensional fast spin echo imaging and the T1 weighting 3-dimensional fast spin echo image after radiography of T1 weighting 3-dimensional fast spin echo imaging.
Concrete, adopt three-dimensional MRI scan, directly adopt T1 weighted sum T2 weighting can save acquisition time, and only need the T1 weighting 3-dimensional fast spin echo image after radiography can obtain required carotid artery image.
Step S40, adopt T1 weighting 3-dimensional fast spin echo imaging and the two-dimentional T2 weighting quick spin echo imaging scanning aorta that combines.
In one embodiment, as shown in Figure 3, step S40 comprises:
Step S410, adopt speckle and speckle position in T1 weighting 3-dimensional fast spin echo image scanning aorta, and measure the size of speckle.
Concrete, adopt T1 Weighted N AV-SPACE to be as the criterion, search speckle and the residing position of speckle in aorta, measure the size of speckle.
Step S420, adopt the black blood interlacing fast acquisition interleaved spin echo of two-dimentional T2 weighting multilamellar to gather image on the speckle position.
Concrete, because adopting three-dimensional T2 weighting program time very long, use two-dimentional T2 weighting multilamellar to deceive blood interlacing fast acquisition interleaved spin echo (dark blood interleaved multi-slice TSE).This sequence is developed by the TSE sequence of standard, uses interlacing the imaging picking rate can be improved to 2 to 3 times.The black blood interlacing fast acquisition interleaved spin echo of two dimension T2 weighting multilamellar is by electrocardiogram triggered, scanning the aortal cycle is heart beat cycle, being the ECG(electrocardiogram) triggering is locked in aortal collection period on the set time of heart beat cycle, and the relevant movement that breathing causes can adopt signal averaging to solve.
Fig. 4 is the black blood interlacing fast acquisition interleaved spin echo figure of two-dimentional T2 weighting multilamellar, in figure, by at a TR(repetition time, repetition time) in, 2 layers of insertions or multilamellar improve the time that the scan efficiency trigger impulse determines TR, IR(Inversion Recovery) be the inversion recovery pulse.Insert multilamellar, just can be at a TR picture of multi-disc, shorten sweep time.Wherein, very weak because of the signal of MRI, for improving the signal to noise ratio of MR, require to reuse same pulse train, be TR this interval time that repeats to excite.In figure, Trig.pulse=1, Trig.pulse=2 is two trigger impulses.A and B are 2 layers.
Step S430, by the 3-D view registration of the two dimensional image of T2 weighting and T1 weighting.
Concrete, by after the 3-D view registration of the two dimensional image of T2 weighting and T1 weighting, can carry out speckle qualitative, qualitative the determining of the features such as speckle volume, area that comprise.
As shown in Figure 5, in one embodiment, a kind of cranium brain, carotid artery and the Trinitarian scanning system of aorta, comprise locating module 10 and scan module 20.Wherein:
Locating module 10, for the location scanning position.
Concrete, for the patient is with upper head and neck radio-frequency coil and heart coil, adopt the localizer location scanning, obtain the location scanning position, do not need to repeat location scanning so that follow-up, save positioning time.
Concrete, the parallel imaging mode can be one or more combinations in T1 weighting 3-dimensional fast spin echo imaging (T1-SPACE), T2 weighting 3-dimensional fast spin echo imaging (T2-SPACE) and the imaging of three-dimensional intensity of magnetization preparation gradin-echo (MPRAGE).In the present embodiment, adopt the Three-Dimensional Magnetic resonance image-forming can improve signal noise ratio (snr) of image, adopt the parallel imaging mode to reduce sweep time.
In one embodiment, as shown in Figure 6, scan module 20 comprises detecting unit 210, collecting unit 220 and registration unit 230.Wherein:
Detecting unit 210, for adopting T1 weighting 3-dimensional fast spin echo image scanning aorta speckle and speckle position, and the size of measurement speckle.
Concrete, adopt T1 Weighted N AV-SPACE to be as the criterion, search speckle and the residing position of speckle in aorta, measure the size of speckle.
Collecting unit 220 gathers image for adopting the black blood interlacing fast acquisition interleaved spin echo of two-dimentional T2 weighting multilamellar on described speckle position.
Concrete, because adopting three-dimensional T2 weighting program time very long, use two-dimentional T2 weighting multilamellar to deceive blood interlacing fast acquisition interleaved spin echo (dark blood interleaved multi-slice TSE).This sequence is developed by the TSE sequence of standard, uses interlacing the imaging picking rate can be improved to 2 to 3 times.The black blood interlacing fast acquisition interleaved spin echo of two dimension T2 weighting multilamellar is by electrocardiogram triggered, scanning the aortal cycle is heart beat cycle, being the ECG(electrocardiogram) triggering is locked in aortal collection period on the set time of heart beat cycle, and the relevant movement that breathing causes can adopt signal averaging to solve.Fig. 4 is the black blood interlacing fast acquisition interleaved spin echo figure of two-dimentional T2 weighting multilamellar, in figure, by at a TR(repetition time, repetition time) in, 2 layers of insertions or multilamellar improve the time that the scan efficiency trigger impulse determines TR, IR(Inversion Recovery) be the inversion recovery pulse.Wherein, very weak because of the signal of MRI, for improving the signal to noise ratio of MR, require to reuse same pulse train, be TR this interval time that repeats to excite.
Concrete, by after the 3-D view registration of the two dimensional image of T2 weighting and T1 weighting, can carry out speckle qualitative, qualitative the determining of the features such as speckle volume, area that comprise.
Above-mentioned cranium brain, carotid artery and the Trinitarian scan method of aorta and system, adopt at first location scanning position, behind location, directly scanning cranium brain, carotid artery and aorta, do not need resetting scanning, shortened sweep time, and adopt the fast imaging method scanning cranium brains such as parallel imaging, reduce sweep time, adopted three-dimensional T1 weighted imaging and two-dimentional T2 weighting quick spin echo imaging in conjunction with the scanning aorta, further shortened sweep time.
The above embodiment has only expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (4)
1. the Trinitarian scan method of cranium brain, carotid artery and aorta comprises the following steps:
The location scanning position;
Adopt the parallel imaging mode in the Three-Dimensional Magnetic resonance image-forming to scan the cranium brain;
Adopt three-dimensional MRI scan carotid artery, gather image, the image of T2 weighting 3-dimensional fast spin echo imaging and the T1 weighting 3-dimensional fast spin echo image after radiography of T1 weighting 3-dimensional fast spin echo imaging;
Adopt T1 weighting 3-dimensional fast spin echo imaging and the two-dimentional T2 weighting quick spin echo imaging scanning aorta that combines;
Described parallel imaging mode can be one or more combinations in the imaging of T1 weighting 3-dimensional fast spin echo, T2 weighting 3-dimensional fast spin echo imaging and the imaging of three-dimensional intensity of magnetization preparation gradin-echo;
Described employing T1 weighting 3-dimensional fast spin echo imaging and two-dimentional T2 weighting quick spin echo imaging combine scanning aortal step comprise:
Adopt speckle and speckle position in T1 weighting 3-dimensional fast spin echo image scanning aorta, and measure the size of speckle;
Adopt the black blood interlacing fast acquisition interleaved spin echo of two-dimentional T2 weighting multilamellar to gather image on described speckle position;
3-D view registration by the two dimensional image of T2 weighting and T1 weighting.
2. cranium brain according to claim 1, carotid artery and the Trinitarian scan method of aorta, is characterized in that, the black blood interlacing sequence of described two-dimentional T2 weighting multilamellar is by electrocardiogram triggered, and the aortal cycle of described scanning is heart beat cycle.
3. the Trinitarian scanning system of cranium brain, carotid artery and aorta, is characterized in that, comprising:
Locating module, for the location scanning position;
Scan module, for adopting the parallel imaging mode of Three-Dimensional Magnetic resonance image-forming to scan the cranium brain, adopt three-dimensional MRI scan carotid artery, gather image, the image of T2 weighting 3-dimensional fast spin echo imaging and the T1 weighting 3-dimensional fast spin echo image after radiography of the imaging of T1 weighting 3-dimensional fast spin echo, and adopt T1 weighting 3-dimensional fast spin echo imaging and the two-dimentional T2 weighting quick spin echo imaging scanning aorta that combines;
Described parallel imaging mode can be one or more combinations in the imaging of T1 weighting 3-dimensional fast spin echo, T2 weighting 3-dimensional fast spin echo imaging and the imaging of three-dimensional intensity of magnetization preparation gradin-echo;
Described scan module comprises:
Detecting unit, adopt speckle and speckle position in T1 weighting 3-dimensional fast spin echo image scanning aorta, and measure the size of speckle;
Collecting unit gathers image for adopting the black blood interlacing fast acquisition interleaved spin echo of two-dimentional T2 weighting multilamellar on described speckle position;
Registration unit, for the 3-D view registration of the two dimensional image by the T2 weighting and T1 weighting.
4. cranium brain according to claim 3, carotid artery and the Trinitarian scanning system of aorta, it is characterized in that, the black blood interlacing fast acquisition interleaved spin echo of described two-dimentional T2 weighting multilamellar is by electrocardiogram triggered, and the aortal cycle of described scanning is heart beat cycle.
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| CN103177448A (en) * | 2013-03-26 | 2013-06-26 | 南昌航空大学 | Method for extracting brain tissues from magnetic resonance brain images in real time |
| KR101649275B1 (en) | 2014-10-21 | 2016-08-18 | 삼성전자주식회사 | Method for acquiring a magnetic resonance imaging and apparatus for acquiring a magnetic resonance imaging thereof |
| CN107510458B (en) * | 2017-08-11 | 2020-09-11 | 上海联影医疗科技有限公司 | Magnetic resonance imaging method and equipment |
| CN111077486A (en) * | 2018-10-19 | 2020-04-28 | 深圳先进技术研究院 | Three-dimensional positive contrast magnetic resonance imaging method, device, equipment and storage medium |
| CN109919935B (en) * | 2019-03-12 | 2021-02-09 | 语坤（北京）网络科技有限公司 | Head and neck blood vessel segmentation method and device |
| CN114041778B (en) * | 2022-01-13 | 2022-06-24 | 康达洲际医疗器械有限公司 | Fusion imaging method and system applied to bone joint magnetic resonance imaging |
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| CN1575748A (en) * | 2003-06-26 | 2005-02-09 | 美国西门子医疗解决公司 | Rapid multislice black blood double-inversion recovery technique for blood vessel imaging |
| CN1785132A (en) * | 2004-12-08 | 2006-06-14 | 西门子公司 | Method for implementing imaging inspection method |
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