CN102716521B - All-sealing screw-in preassembly-type medicine feeder - Google Patents

All-sealing screw-in preassembly-type medicine feeder Download PDF

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Publication number
CN102716521B
CN102716521B CN 201210224553 CN201210224553A CN102716521B CN 102716521 B CN102716521 B CN 102716521B CN 201210224553 CN201210224553 CN 201210224553 CN 201210224553 A CN201210224553 A CN 201210224553A CN 102716521 B CN102716521 B CN 102716521B
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China
Prior art keywords
rotary sleeve
fairlead
guide
cartridge case
feeding device
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CN 201210224553
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Chinese (zh)
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CN102716521A (en
Inventor
邱宇
李科
袁媛
李鸿宇
黄叶莉
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Chongqing Lummy Pharmaceutical Co Ltd
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Chongqing Lummy Pharmaceutical Co Ltd
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Priority to CN 201210224553 priority Critical patent/CN102716521B/en
Priority to PCT/CN2012/079609 priority patent/WO2013149445A1/en
Priority to US14/415,605 priority patent/US9839581B2/en
Priority to CA2877515A priority patent/CA2877515C/en
Priority to EP12873551.1A priority patent/EP2845578B1/en
Publication of CN102716521A publication Critical patent/CN102716521A/en
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Publication of CN102716521B publication Critical patent/CN102716521B/en
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Abstract

The invention discloses an all-sealing screw-in preassembly-type medicine feeder which comprises a medicine feeding cylinder, a medicine feeding crosspointer, a guide sleeve, a rotation sleeve and a pushing rod. The guide sleeve and the medicine feeding cylinder are in sealing joint, a guide spiral groove is arranged on the inner wall of the guide sleeve, one end of the rotation sleeve stretches into the guide sleeve, and the other end of the rotation sleeve is a sealing end. A guide through groove is arranged on the lateral wall of the rotation sleeve along the axial direction, the pushing rod is arranged in the rotation sleeve along the axial direction, and a guide block which penetrates through the guide through groove and stretches into the guide spiral groove is arranged on the pushing rod. When the all-sealing screw-in preassembly-type medicine feeder is used, a medicine container and the medicine feeding crosspointer are kept in a sealing state through a separation film and the rotation sleeve and achieve absolutely sterile of transportation and storage. The rotation sleeve is rotated to drive the pushing rod to rapidly move downwards along the guide spiral groove, an upper needle tip of the medicine feeding crosspointer pierces a sealing plug on the medicine container, a lower needle tip of the medicine feeding crosspointer pierces the separation film in a connector to enable the medicine container and a transfusion container to be communicated in the twinkling of an eye, and sterile sealing of the whole process of transportation, storage, joint, medicine mixing and transfusion is achieved.

Description

Hermetically sealed precession prepackage type drug feeding device
Technical field
The present invention relates to a kind of medical apparatus and instruments, the drug feeding device that uses when relating in particular to a kind of mixed medicine.
Background technology
For the medicine in the medicament reservoir being added in the solution in the infusion vessel (being transfusion flexible bag or soft transfusion bottle), then mixed solution is imported such as the patient in the clinical mechanism of hospital.In the prior art, often adopt drug feeding device that medicament reservoir is connected with transfusion flexible bag or soft transfusion bottle.
Drug feeding device of the prior art mainly comprises and adds cartridge case and dosing crosspointer, the dosing tube forms cup-like structure, the dosing crosspointer is stuck in by the crosspointer supporting seat and adds in the cartridge case, in order to seal mixing the medicine passage, be provided with barrier film at the bottom interior wall cross section that adds cartridge case, be provided with diaphragm seal on the top that adds cartridge case, a needle point of dosing crosspointer is corresponding with barrier film, and another needle point of dosing crosspointer is corresponding with the diaphragm seal of top.During use, this is added cartridge case docks with the interface of transfusion flexible bag or soft transfusion bottle, tear the diaphragm seal that adds on the cartridge case top, again medicament reservoir is snapped in and add in the cartridge case, also promoting the dosing crosspointer when medicament reservoir snaps in moves down, the last needle point of dosing crosspointer pierces through the sealing-plug on the medicament reservoir, the broken barrier film of the following acupuncture of dosing crosspointer and pierce through transfusion flexible bag or soft transfusion bottle on interface on sealing-plug, extruding transfusion flexible bag or soft transfusion bottle just can realize mixing medicine.
Adopt the drug feeding device of said structure, in mixed medicine process, mainly have following deficiency: snap in when adding in the cartridge case at medicament reservoir, must tear initiation add the diaphragm seal on the cartridge case top, and add cartridge case when snapping in and to contact with the external world, and then pollute.And all closed drug feeding devices that occur in the prior art all can only be implemented in and mix the airtight of medicine process, and can not realize cillin bottle and drug feeding device dock, mix medicine and " overall process is sterile closed " when infusing.
Summary of the invention
At above shortcomings in the prior art, the invention provides a kind of can under the integral asepsis state, dock, mix medicine and the airtight hermetically sealed precession prepackage type drug feeding device of transfusion overall process.
In order to solve the problems of the technologies described above, the present invention has adopted following technical scheme:
Hermetically sealed precession prepackage type drug feeding device comprises adding cartridge case, dosing crosspointer, fairlead, rotary sleeve and push rod that described dosing crosspointer is located at and adds in the cartridge case;
A described end that adds cartridge case is the interface link, and a needle point of described dosing crosspointer is corresponding with the interface link;
The inwall of described fairlead arranges the guiding helicla flute, and an end of described fairlead docks with the other end sealing that adds cartridge case;
One end of described rotary sleeve puts in the fairlead and with fairlead axial restraint, radially rotatable cooperation the, and rotary sleeve and fairlead and is sealed and matched; The other end of described rotary sleeve is sealed end; The sidewall upper edge of described rotary sleeve is axially arranged with guide groove;
Described push rod is axially disposed within the rotary sleeve along rotary sleeve, is provided with guide pad at the outer wall of push rod, and described guide pad passes guide groove and puts in the guiding helicla flute.
As a preferred embodiment of the present invention, be symmetrical arranged two guiding helicla flutes on the inwall of described fairlead, be arranged with two guide grooves that arrange vertically on the sidewall of described rotary sleeve, be arranged with two guide pads on the outer wall of described push rod, one of them guide pad passes a guide groove and stretches in the guiding helicla flute, and another guide pad passes another guide groove and stretches in another guiding helicla flute.
As another kind of preferred version of the present invention, the outer wall of described rotary sleeve is along being circumferentially with pressure ring, and described pressure ring is pressed on the other end of fairlead and with it and is sealed and matched.
As another preferred version of the present invention, described pressure ring is sealed and matched by the other end of sealing ring and fairlead.
As a kind of improvement project of the present invention, on the described inwall that adds cartridge case and near the interface link annular rubber cushion is set, the needle point that described dosing crosspointer is corresponding with the interface link passes annular rubber cushion.
As another kind of improvement project of the present invention, the described inwall that adds the interface link of cartridge case is a throat structure.
As another improvement project of the present invention, described push rod is arranged in the rotary sleeve along the axis of rotary sleeve, and another needle point of described dosing crosspointer is corresponding with push rod.
Scheme as a further improvement on the present invention, a segment distance is extended at the two ends of described guide groove in the opposite direction on the circumference of rotary sleeve; The direction that extend at the circumference of rotary sleeve the bottom of described guide groove direction of rotation of rotary sleeve when promoting is consistent.
Scheme as a further improvement on the present invention, the bottom of described interface link is provided with the clip assembly that is connected with the interface link for the interface with infusion vessel.
As further improvement project more of the present invention, on the described inwall that adds cartridge case and be symmetrically arranged with at least two near the interface link and be barb-like anti-slide fastener.
The invention has the beneficial effects as follows: when using this hermetically sealed precession prepackage type drug feeding device, will add cartridge case earlier and dock with interface on transfusion flexible bag or the soft transfusion bottle, and medicament reservoir is pre-loaded into will add in the cartridge case, again with fairlead with add the cartridge case sealing and dock.Rotary sleeve by the sealing of the barrier film in the interface and an end makes medicament reservoir and dosing crosspointer be in sealing state, therefore, can reach transportation and store absolute aseptic.When mixing medicine, rotation rotary sleeve driving push rod moves down rapidly along the guiding helicla flute of fairlead inwall, press on the medicament reservoir, and then promotion dosing crosspointer moves down, the last needle point of dosing crosspointer pierces through the sealing-plug on the medicament reservoir, the following needle point of dosing crosspointer punctures the barrier film in the interface, medicament reservoir was communicated with moment in transfusion flexible bag or the soft transfusion bottle, whole process all is in aseptic butt joint, therefore, it is sterile closed that the overall process of medicine and transfusion can be realized transporting, stores, docks, be mixed to this hermetically sealed precession prepackage type drug feeding device.
Description of drawings
Fig. 1 is the structural representation of hermetically sealed precession prepackage type drug feeding device;
Fig. 2 is the cross-sectional view that adds cartridge case;
Fig. 3 is the cross-sectional view of fairlead;
Fig. 4 is the front view of rotary sleeve;
Fig. 5 is along the cross section view of A-A direction among Fig. 4;
Fig. 6 is the cross-sectional view of push rod;
Fig. 7 is the perspective view of push rod;
Fig. 8 is connected on the infusion vessel for hermetically sealed precession prepackage type drug feeding device and is in and uses preceding structural representation;
Fig. 9 for hermetically sealed precession prepackage type drug feeding device be connected on the infusion vessel and be in use after structural representation.
In the accompanying drawing: 1-add cartridge case; 2-dosing crosspointer; 3-fairlead; 4-rotary sleeve; 5-push rod; 6-interface link; 7-guiding helicla flute; 8-guide groove; 9-guide pad; 10-pressure ring; 11-sealing ring; 12-annular rubber cushion; 13-suspension ring; 14-infusion vessel; 15-crosspointer supporting seat; 16-anti-slide fastener; 17-medicament reservoir; 18-annular snap; 19-annular groove; 20-annular slot; 21-passage; 22-interface; 23-barrier film; 24-clip assembly.
The specific embodiment
Below in conjunction with the drawings and specific embodiments the present invention is done to describe in further detail.
As shown in Figure 1, hermetically sealed precession prepackage type drug feeding device comprises adding cartridge case 1, dosing crosspointer 2, fairlead 3, rotary sleeve 4 and push rod 5.
Wherein, add the structure of cartridge case as shown in Figure 2, the bottom that adds cartridge case 1 is interface link 6, and the inwall of interface link 6 is a throat structure, and being more conducive to infusion vessel 14(like this is transfusion flexible bag or soft transfusion bottle) interface size coupling.Add the inwall of cartridge case 1 and be provided with annular rubber cushion 12 near interface link 6, the dosing crosspointer 2 of dosing crosspointer 2(present embodiment adopts the cross pin, be the last pin of dosing crosspointer 2, down pin and crosspointer supporting seat 15 are one-body molded) be located at and add in the cartridge case 1, the following needle point of dosing crosspointer 2 passes annular rubber cushion 12 and is stuck on the annular rubber cushion 12, and the crosspointer supporting seat 15 of dosing crosspointer 2 is positioned at the top of annular rubber cushion 12.Being symmetrically arranged with at least two at the inwall that adds cartridge case 1 is in the barb-like anti-slide fastener 16(present embodiment, be symmetrically arranged with four anti-slide fasteners at the inwall that adds cartridge case 1), medicament reservoir 17 pack into add in the cartridge case 1 after, when medicament reservoir 17 mixes medicine with infusion vessel 14 (as shown in Figure 9), the bottle cap of medicament reservoir 17 is stuck in the below of anti-slide fastener 16, should can stop medicament reservoir 17 to retreat effectively by anti-slide fastener 16, ensure that mixing medicine carried out smoothly.
The structure of fairlead 3 as shown in Figure 3, (mode that can adopt seam) docked in the bottom of fairlead 3 with the end sealing that adds cartridge case 1, the inwall of fairlead 3 arranges guiding helicla flute 7, in the present embodiment, is symmetrical arranged two guiding helicla flutes 7 on the inwall of fairlead 3.Edge, inwall top at fairlead 3 is circumferentially with annular snap 18, along the circumferential direction is provided with annular groove 19 on the top end face of fairlead 3.
The structure of rotary sleeve 4 as shown in Figure 4 and Figure 5, the bottom of rotary sleeve 4 puts in the fairlead 3 and with fairlead 3 axial restraints, radially rotatable cooperation the, and rotary sleeve 4 and fairlead 3 and is sealed and matched, the top of rotary sleeve 4 is sealed end.In the present embodiment, be circumferentially with pressure ring 10 on the outer wall edge of rotary sleeve 4, the edge is circumferentially with annular slot 20 below pressure ring 10.After rotary sleeve 4 was installed on the fairlead 3, annular snap 18 was positioned at annular slot 20, and sealing ring 11 is installed in annular groove 19, and pressure ring 10 is pressed in by sealing ring 11 on the top of fairlead 3 and with it and is sealed and matched.When rotating rotary sleeve 4, annular snap 18 is rotated in annular slot 20, because of the sealing function of sealing ring 11, makes rotary sleeve 4 both rotatable in fairlead 3, can realize the outer wall of rotary sleeve 4 and the top seal of fairlead 3 again.The sidewall upper edge of rotary sleeve 4 is axially arranged with in the guide groove 8(present embodiment, is arranged with two guide grooves 8 that arrange vertically on the sidewall of rotary sleeve 4).A segment distance is extended at the two ends of guide groove 8 in the opposite direction on the circumference of rotary sleeve 4, form the guide groove 8 of " z " font, the direction that extend at the circumference of rotary sleeve 4 bottom of guide groove 8 during with promotion the direction of rotation of rotary sleeve 4 consistent.Before medicament reservoir 17 and infusion vessel 14 mix medicine (as shown in Figure 8), guide pad 9 on the push rod 5 is positioned at the groove of guide groove 8 top circumferencial directions, stoped push rod 5 axially to move from following along it effectively, moved down thereby avoided push rod 5 before mixing medicine, to promote medicament reservoir 17; When medicament reservoir 17 mixes medicine with infusion vessel 14 (as shown in Figure 9), guide pad 9 on the push rod 5 is positioned at the groove of guide groove 8 bottom circumferencial directions, stoped effectively push rod 5 along it axially from last movement, thereby stop medicament reservoir 17 to retreat effectively, further ensure that mixing medicine carries out smoothly.
The structure of push rod 5 as shown in Figure 6 and Figure 7, push rod 5 is axially disposed within the rotary sleeve 4 along rotary sleeve 4, push rod 5 is the hollow structure of upper end open, lower end sealing, and push rod 5 forms the hollow structure that the top diameter of bores are big, the bottom diameter of bore is little.Base wall at the top endoporus is evenly equipped with the passage 21 that arranges vertically, and when push rod 5 moved down process, this passage 21 was conducive to the gas flow upper space in the lower space, reduced the air drag that push rod 5 moves down.Outer wall at push rod 5 is arranged with two guide pads 9, and one of them guide pad 9 passes a guide groove 8 and stretches in the guiding helicla flute 7, and another guide pad 9 passes another guide groove 8 and stretches in another guiding helicla flute 7.Push rod 5 is arranged in the rotary sleeve 4 along the axis of rotary sleeve 4, the last needle point of dosing crosspointer 2 is corresponding with push rod 5, medicament reservoir 17 be placed on add in the cartridge case 1 after, the center, top of the bottom of push rod 5 and medicament reservoir 17 is corresponding, the last needle point of dosing crosspointer 2 is corresponding with the bottle cap of medicament reservoir 17.
The bottom of interface link 6 is provided with the clip assembly 24 that is connected with interface link 6 for the interface with infusion vessel 14.The interface link 6 that adds cartridge case 1 just can be realized being tightly connected by clip assembly 24 with 22 need of interface on the infusion vessel 14.(being the top of rotary sleeve 4) is provided with suspension ring 13 on the sealed end of rotary sleeve 4, and the infusion vessel 14(that can connect with this drug feeding device and with drug feeding device by these suspension ring 13 is as shown in Figure 8) be suspended on the used bracing frame of transfusion.
When this hermetically sealed precession prepackage type drug feeding device and infusion vessel assembling, at first will add the interface link 6 of cartridge case 1 and the interface 22 on the infusion vessel 14 is tightly connected by clip assembly 24, again medicament reservoir 17 is placed on and adds in the cartridge case 1, then with fairlead 3 seam on the top that adds cartridge case 1, again push rod 5 is installed in the rotary sleeve 4, and make guide pad 9 on the push rod 5 pass guide groove 8 on the rotary sleeve 4, at last that the guide pad 9 on the push rod 5 is corresponding with guiding helicla flute 7 on the fairlead 3, after being installed in rotary sleeve 4 on the fairlead 3, guide pad 9 stretches in the guiding helicla flute 7.
When using this hermetically sealed precession prepackage type drug feeding device, interface 22 on the interface link 6 that will add cartridge case 1 earlier and the infusion vessel 14 is by clip assembly 24 be tightly connected (also can adopt the mode of seam and realize being tightly connected with the mode that is threaded), in the present embodiment, infusion vessel 14 adopts transfusion flexible bag, as shown in Figure 8, medicament reservoir 17 is pre-loaded under aseptic condition adds in the cartridge case 1, make medicament reservoir 17 and dosing crosspointer 2 be in sealing state by the barrier film 23 in the interface 22 and the rotary sleeve 4 of end sealing, therefore, can reach transportation and store absolute aseptic.When mixing medicine, rotate rotary sleeve 4, rotary sleeve 4 drives push rod 5 and moves down rapidly along the guiding helicla flute 7 on fairlead 3 inwalls, directly press on the medicament reservoir 17, and then promotion dosing crosspointer 2 moves down, the last needle point of dosing crosspointer 2 pierces through the sealing-plug on the medicament reservoir 17, the following needle point of dosing crosspointer 2 punctures the barrier film 23 in the interface 22, medicament reservoir 17 was communicated with moment in the transfusion flexible bag, as shown in Figure 9, whole process all is in aseptic butt joint, and whole process all moves down realization by rotating rotary sleeve 4 driving push rods 5.And push rod 5 moves down and need rotate and could realize by dependence rotary sleeve 4, so can prevent in transportation and storing push rod 5 force medication containers 17.When the guide pad 9 on the push rod 5 moved down in the groove of guide groove 8 bottom circumferencial directions, medicament reservoir 17 was pushed to the below that bottle cap is positioned at anti-slide fastener 16, stops medicament reservoir 17 to retreat effectively, ensured that mixing medicine carries out smoothly.Because this hermetically sealed precession prepackage type drug feeding device is finished until transfusion after being pre-loaded into medicament reservoir, related medicament reservoir with all be in aseptic condition with parts that medicine directly contacts, therefore, can realize that medicine is sterile closed in the overall process of transportation, storage, butt joint, mixed medicine and transfusion.Before mixing medicine and during mixed medicine, medicament reservoir 17 all is in and adds in the cartridge case 1, made by transparent material because adding cartridge case 1, operator only need by the transparent information that cartridge case 1 just can be observed the thing that makes up a prescription on the medicament reservoir 17 that adds, be conducive to the operator and in time grasp the drug information of joining, avoid the medicine mispairing.
Explanation is at last, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although with reference to preferred embodiment the present invention is had been described in detail, those of ordinary skill in the art is to be understood that, can make amendment or be equal to replacement technical scheme of the present invention, and not breaking away from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.

Claims (8)

1. hermetically sealed precession prepackage type drug feeding device comprises adding cartridge case (1) and dosing crosspointer (2), and described dosing crosspointer (2) is located at and adds in the cartridge case (1), it is characterized in that: also comprise fairlead (3), rotary sleeve (4) and push rod (5);
A described end that adds cartridge case (1) is interface link (6), and a needle point of described dosing crosspointer (2) is corresponding with interface link (6);
The inwall of described fairlead (3) arranges guiding helicla flute (7), and an end of described fairlead (3) docks with the other end sealing that adds cartridge case (1);
One end of described rotary sleeve (4) puts in the fairlead (3) and with fairlead (3) axial restraint, radially rotatable cooperation the, and rotary sleeve (4) and fairlead (3) and is sealed and matched; The other end of described rotary sleeve (4) is sealed end; The sidewall upper edge of described rotary sleeve (4) is axially arranged with guide groove (8);
Described push rod (5) is axially disposed within the rotary sleeve (4) along rotary sleeve (4), is provided with guide pad (9) at the outer wall of push rod (5), and described guide pad (9) passes guide groove (8) and puts in the guiding helicla flute (7);
Described dosing crosspointer (2) adopts the cross pin, and the last pin of dosing crosspointer (2), following pin and crosspointer supporting seat (15) are one-body molded; The inwall of described interface link (6) is a throat structure; Be symmetrically arranged with at least two at the inwall that adds cartridge case (1) and be barb-like anti-slide fastener (16).
2. hermetically sealed precession prepackage type drug feeding device according to claim 1, it is characterized in that: be symmetrical arranged two guiding helicla flutes (7) on the inwall of described fairlead (3), be arranged with two guide grooves (8) that arrange vertically on the sidewall of described rotary sleeve (4), be arranged with two guide pads (9) on the outer wall of described push rod (5), one of them guide pad (9) passes a guide groove (8) and stretches in the guiding helicla flute (7), and another guide pad (9) passes another guide groove (8) and stretches in another guiding helicla flute (7).
3. hermetically sealed precession prepackage type drug feeding device according to claim 2 is characterized in that: the outer wall of described rotary sleeve (4) is along being circumferentially with pressure ring (10), and described pressure ring (10) is pressed on the other end of fairlead (3) and with it and is sealed and matched.
4. hermetically sealed precession prepackage type drug feeding device according to claim 3 is characterized in that: described pressure ring (10) is sealed and matched by the other end of sealing ring (11) with fairlead (3).
5. hermetically sealed precession prepackage type drug feeding device according to claim 4, it is characterized in that: on the described inwall that adds cartridge case (1) and near interface link (6) annular rubber cushion (12) is set, the needle point that described dosing crosspointer (2) is corresponding with interface link (6) passes annular rubber cushion (12).
6. hermetically sealed precession prepackage type drug feeding device according to claim 5, it is characterized in that: described push rod (5) is arranged in the rotary sleeve (4) along the axis of rotary sleeve (4), and another needle point of described dosing crosspointer (2) is corresponding with push rod (5).
7. according to the described hermetically sealed precession prepackage type drug feeding device of each claim in the claim 1 to 6, it is characterized in that: a segment distance is extended at the two ends of described guide groove (8) in the opposite direction on the circumference of rotary sleeve (4); The direction of rotation of the direction that extend at the circumference of rotary sleeve (4) bottom of described guide groove (8) rotary sleeve (4) when promoting is consistent.
8. according to the described hermetically sealed precession prepackage type drug feeding device of each claim in the claim 1 to 6, it is characterized in that: the bottom of described interface link (6) is provided with the clip assembly (24) that is connected with interface link (6) for the interface with infusion vessel (14).
CN 201210224553 2012-04-06 2012-07-02 All-sealing screw-in preassembly-type medicine feeder Active CN102716521B (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN 201210224553 CN102716521B (en) 2012-04-06 2012-07-02 All-sealing screw-in preassembly-type medicine feeder
PCT/CN2012/079609 WO2013149445A1 (en) 2012-04-06 2012-08-02 Preassembled medicine mixer
US14/415,605 US9839581B2 (en) 2012-04-06 2012-08-02 Preassembled medicine mixer
CA2877515A CA2877515C (en) 2012-04-06 2012-08-02 Preassembled medicine mixer
EP12873551.1A EP2845578B1 (en) 2012-04-06 2012-08-02 Preassembled medicine mixer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201210099109.6 2012-04-06
CN201210099109 2012-04-06
CN 201210224553 CN102716521B (en) 2012-04-06 2012-07-02 All-sealing screw-in preassembly-type medicine feeder

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CN102716521A CN102716521A (en) 2012-10-10
CN102716521B true CN102716521B (en) 2013-08-14

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Publication number Priority date Publication date Assignee Title
CA2945533C (en) * 2014-04-16 2018-10-16 Becton Dickinson and Company Limited Fluid transfer device with axially and rotationally movable portion
CN105169521B (en) * 2014-05-26 2022-09-02 上海康德莱企业发展集团股份有限公司 Core bar for pre-filling type catheter flusher
CN105126193B (en) * 2014-05-26 2022-09-02 上海康德莱企业发展集团股份有限公司 Inner core rod for core rod of pre-filling type catheter flusher

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JP4241108B2 (en) * 2003-03-14 2009-03-18 住友ベークライト株式会社 Chemical solution preparation kit
CN2902281Y (en) * 2006-04-20 2007-05-23 刘会臣 Sealed type integrated dosage transfusion bottle
CN202113338U (en) * 2011-06-22 2012-01-18 重庆莱美药业股份有限公司 Medicine mixing nozzle

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