CN102707421A - Full-automatic 30-magnification object lens for urine visible analyzer - Google Patents
Full-automatic 30-magnification object lens for urine visible analyzer Download PDFInfo
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- CN102707421A CN102707421A CN2012102050538A CN201210205053A CN102707421A CN 102707421 A CN102707421 A CN 102707421A CN 2012102050538 A CN2012102050538 A CN 2012102050538A CN 201210205053 A CN201210205053 A CN 201210205053A CN 102707421 A CN102707421 A CN 102707421A
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Abstract
The invention relates to a full-automatic 30-magnification object lens for a urine visible analyzer, belonging to a medical 30-magnification microobjective and comprising a lens group and a mechanical structure assembly, wherein the lens group forms an optical system of the microobjective and comprises a negative balsaming lens group I, a balsaming lens group II, a balsaming lens group III, a meniscus lens and a thick lens and includes 8 lenses; and parallel light passes through the optical system of the microobjective and then is focused on a specimen to be tested, and the maximum view field is phi 26mm. while function perfection is ensured, higher shooting speed and more specimen cell details in comparison with the traditional 20-magnification objective can be provided, thus information contents are increased, and better processing property is achieved.
Description
Technical field
The present invention relates to a kind of medical 30 and show the speck mirror, particularly can be applicable to automatically urinate tangible analyser or other stream type cell analyzer device.
Background technology
Urinalysis is a kind of conventional sense project in the clinical examination, for diagnosis foundation is provided through urinalysis.The tangible analyser of full-automatic at present urine adopts 20 times of object lens, and it is similar basically with artificial microexamination principle that it detects principle, all is to amplify the form of observing visible component intuitively.The multiplying power of object lens and resolution are its keys to the details resolution characteristic of restriction.
Summary of the invention
The present invention provides the tangible analyser of a kind of full-automatic urine with 30 times of object lens, to solve the deficiency of prior art.
The technical scheme that the present invention takes is: it is made up of lens combination, physical construction assembly; Lens combination constitutes the optical system of microcobjective; Said microcobjective is the flat field achromatic optical system; It is made up of 5 groups of lens combination, comprising: negative balsaming lens group one, balsaming lens group two, balsaming lens group three, meniscus lens and thick lens, totally 8 lens; It is characterized in that:
Directional light focuses on the tested sample through after the optical system of this microcobjective, and its maximum field of view is φ 26mm;
Said microcobjective is under maximum field of view, and the scope of effective working distance d is 0-8mm;
Numerical aperture is at least 0.55.
Microcobjective according to the invention can be applicable in the optical imaging system of full-automatic urine sediments analyzer and other stream type cell analyzer device.
Advantage of the present invention is: 30 times optics enlargement ratio and 0.55 numerical aperture; Improved the resolution of system; Can obtain more urine specimen visible component information, be easy to algorithm identified and counting, because the diversity of clinical sample; The classification of technology never only is clinical other 12 kind that needs to divide; Be greater than erythrocytic area such as leukocytic area in theory, but part sample singularity causes this rule to be broken, and causes problem space to be identified huge; Actual identification space is far above 12 kinds through collecting the various aspect graph pictures of various visible components in the clinical sample; Can obtain more visible component key feature, set up very representational urinary formed element analysis image storehouse, to 18 kinds of visible components in the urine: red blood cell, leucocyte, leucocyte group, squamous cell, non-squamous cell, hyalina, pathology cast, crystallization, yeast, bacterium, sperm, mucus etc. are carried out effectively classification automatically and counting.These images show on screen after the image processor computing; Classify according to particle size simultaneously and count, the image after the processing is discerned by computing machine, according to the width of particle in the image with length is cut apart and feature extraction; Be divided into different brackets and counting; Obtain the count value of particle under the different stage, utilize in the sample storehouse rich in natural resources, solve effectively and detect the diversified problem of sample in clinical as train samples.The shooting time that has shortened sample is observed in big visual field, has improved arithmetic speed, the test speed of existing instrument be 60 samples/hour; For the work for inspection amount of large hospital, detection speed can not satisfy application requirements, needs further to improve check speed; The Urine Analyzer check speed that is applied to native system be 200 samples/hour; Have longer operating distance and symmetrical structure simultaneously, practice thrift cost, be easy to processing.
Description of drawings
Fig. 1 is the structural representation of object lens of the present invention, and mark 6 is a microslide among the figure;
Fig. 2 is that the focal power of objective lens optical system of the present invention is distributed synoptic diagram;
Fig. 3 is an object lens aberration synoptic diagram of the present invention;
Fig. 4 is the curvature of field and distortion synoptic diagram of object lens of the present invention;
Fig. 5 is the ray aberration synoptic diagram of object lens of the present invention.
Embodiment
It is made up of lens combination, physical construction assembly; Lens combination constitutes the optical system of microcobjective; Said microcobjective is the flat field achromatic optical system; It is made up of 5 groups of lens combination, comprising: negative balsaming lens group 1, balsaming lens group 22, balsaming lens group 33, meniscus lens 4 and thick lens 5, totally 8 lens;
Directional light focuses on the tested sample through after the optical system of this microcobjective, and its maximum field of view is φ 26mm;
Said microcobjective is under maximum field of view, and the scope of effective working distance d is 0-8mm;
Numerical aperture is at least 0.55.
Microcobjective according to the invention can be applicable in the optical imaging system of full-automatic urine sediments analyzer and other stream type cell analyzer device.
30 times of object lens in the present embodiment are applied to automatically urinate tangible analyser; This analyser comprises that an automatic sampling apparatus provides sample; Sample is extracted in the liquid-way system through probe by syringe pump; Form laminar flow in the middle of being clipped in sheath fluid, be pushed in the column type flow chamber by sample injector, constant speed is sent to flow cell under sheath fluid drives.Aperture diaphragm is negative above the balsaming lens group 1; The directional light that is sent by stroboscopic light source is from aperture diaphragm incident; Through negative balsaming lens group 1, balsaming lens group 22, balsaming lens group 33, meniscus lens 4 and thick lens 5, after seeing through the pool wall that flows, focus on the sample to be tested.After optical system; Receiving trap obtains image information, on the screen of computing machine, shows, and the while classifies according to particle size and counts; Image after the processing is discerned by computing machine; To the width of particle in the image with length is cut apart and feature extraction, be divided into different brackets and counting, obtain the count value of different stage particle.
The focal power of object lens is assigned as Φ; The focal power of negative balsaming lens group 1 is-0.05; The focal power of balsaming lens group 22 is 0.027, the focal power of balsaming lens group 33 is 0.015, the focal power of meniscus lens 4 is 0.035, the focal power of thick lens 5 is 0.048, and this kind distribution can avoid producing excessive senior aberration.
According to Gauss formula, calculate the primary aberration of system.
Utilize formula:
Wherein U is the object space aperture angle, and U is picture side's aperture angle, and L is an object distance, and I is an incident angle, and I is an emergence angle, and R is a radius-of-curvature, and N is an air refraction, and N is a medium refraction index.
By Laplace invariant J=nuy=0.22
∑SI=∑h（hφ）2 P+ SI
∑SII=∑h2（hφ）3 P+ J∑（hφ）2 W + SI
∑SⅢ=∑h2（hφ）3 P+ 2J∑（hφ）2 W h2 + J2 ∑φ+SII
Wherein n is a refractive index, and u is an aperture angle, and y is a height of incidence, and ∑ is summation, SI, SII, S III be respectively filling in of elementary spherical aberration, coma, astigmatism and coefficient, P/W is that coefficient, the h φ of PW method is the focal power of cellular system.
Obtain the aberration of system:
Spherical aberration S1=0.0002015
Coma S2=-0.0039594
Astigmatism S3=0.0000515
Curvature of field S4=0
Axial chromatic aberration C1=-0.0019516
Chromatic longitudiinal aberration C2=0.0027562
According to above-mentioned primary aberration value, calculate the initial solution data and be:
Focal distance f=6.67, numerical aperture NA=0.55, β=30
r1= -7.152 d1=4 nd=1.76 vd=27.5
r2= -8.7723 d2=13.226
r3= 45.3328 d3=3 nd=1.66 vd=54.7
r4= -13.015 d4=2 nd=1.85 vd=23.8
r5= -48.772 d5=1
r6= 11.213 d6=3 nd=1.76 vd=27.5
r7= -431.34 d7=0.3324
r8= 10.691 d8=7 nd=1.57 vd=56
r9= 9.461
Wherein, r1 ~ r9 is the radius-of-curvature of lens, and d1, d3, d4, d6, d8 are the thickness of lens, and d2, d5, d7 are the airspace, and nd is the refractive index of optical glass under d light, and vd is an abbe number.
More than draw the initial solution of camera lens for the PW method, it is following that optimization behind the above data input ZEMAX software is obtained final data:
Focal distance f=6.67, numerical aperture NA=0.55, β=30
r1= -9.24~ -9.25 d1=4.4 ~ 4.5 nd=1.62 vd=60.3
r2= 9.24~ 9.25 d2=4.4~ 4.6 nd=1.67 vd=32.2
r3= -39.8~ -40.1
r4= -283.4~ -283.5 d3=5.5~ 5.6 nd=1.76 vd=27.5
r5= 16.4~ 16.5 d4=4.9~ 5.1 nd=1.66 vd=54.7
r6= -23.2~ -23.4
r7= 23.2~ 23.4 d5=5 nd=1.66 vd=54.7
r8= -16.4~ -16.5 d6=5.55 nd=1.76 vd=27.5
r9= 283.5~ 283.6
r10= 8.7~ 8.9 d7=3.2~3.4 nd=1.5 vd=81.6
r11= 22.5~ 22.7
r12= 7.7~ 7.8 d8=3.4~3.6 nd=1.66 vd=54.7
r13= 7.7~ 7.8
As stated,, when assurance function is perfect, shooting speed faster can be provided, than existing 20 times of object lens more sample cell details, thereby improve quantity of information, and have the favorable manufacturability ability according to the present invention.
Claims (3)
1. the tangible analyser of full-automatic urine is with 30 times of object lens; It is made up of lens combination, physical construction assembly; Lens combination constitutes the optical system of microcobjective, and said microcobjective is the flat field achromatic optical system, and it is made up of 5 groups of lens combination; Comprise: negative balsaming lens group one, balsaming lens group two, balsaming lens group three, meniscus lens and thick lens, totally 8 lens; It is characterized in that: directional light focuses on the tested sample through after the optical system of this microcobjective, and its maximum field of view is φ 26mm.
2. the tangible analyser of full-automatic urine according to claim 1 is characterized in that with 30 times of object lens: said microcobjective is under maximum field of view, and the scope of effective working distance d is 0-8mm.
3. the tangible analyser of full-automatic urine according to claim 1 and 2 is with 30 times of object lens, and it is characterized in that: numerical aperture is at least 0.55.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102050538A CN102707421A (en) | 2012-06-20 | 2012-06-20 | Full-automatic 30-magnification object lens for urine visible analyzer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012102050538A CN102707421A (en) | 2012-06-20 | 2012-06-20 | Full-automatic 30-magnification object lens for urine visible analyzer |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101211007A (en) * | 2006-12-28 | 2008-07-02 | 亚洲光学股份有限公司 | Image-forming objective lens |
| CN101214167A (en) * | 2008-01-04 | 2008-07-09 | 中国人民解放军第四军医大学 | Pediculus arcus vertebralis screw nail nail-path partial point-like curing method and matching with hollow side opening tap |
| CN102141677A (en) * | 2010-02-01 | 2011-08-03 | 奥林巴斯株式会社 | Microscope objective lens |
| JP2011175238A (en) * | 2010-02-01 | 2011-09-08 | Olympus Corp | Microscope objective lens |
| CN102200629A (en) * | 2011-05-26 | 2011-09-28 | 桂林电子科技大学 | 100*CaF2-excluding plan apochromatic metallographic microobjective |
| CN202171681U (en) * | 2011-05-26 | 2012-03-21 | 桂林电子科技大学 | 100x Flat field apochromatic metallographic microscope objective without CaF2 |
-
2012
- 2012-06-20 CN CN2012102050538A patent/CN102707421A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101211007A (en) * | 2006-12-28 | 2008-07-02 | 亚洲光学股份有限公司 | Image-forming objective lens |
| CN101214167A (en) * | 2008-01-04 | 2008-07-09 | 中国人民解放军第四军医大学 | Pediculus arcus vertebralis screw nail nail-path partial point-like curing method and matching with hollow side opening tap |
| CN102141677A (en) * | 2010-02-01 | 2011-08-03 | 奥林巴斯株式会社 | Microscope objective lens |
| JP2011175238A (en) * | 2010-02-01 | 2011-09-08 | Olympus Corp | Microscope objective lens |
| CN102200629A (en) * | 2011-05-26 | 2011-09-28 | 桂林电子科技大学 | 100*CaF2-excluding plan apochromatic metallographic microobjective |
| CN202171681U (en) * | 2011-05-26 | 2012-03-21 | 桂林电子科技大学 | 100x Flat field apochromatic metallographic microscope objective without CaF2 |
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Application publication date: 20121003 |