CN102671127A - Traditional Chinese medicine preparation for treating cervical spondylosis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating cervical spondylosis. Effective components in each 100 g of the preparation are prepared from the medicine materials according to the following dose: 5-8 g of angelica sinensis, 10-15 g of ligusticum wallichii, 10-12 g of kudzuvine root, 8-10 g of notopterygium root, 12-18 g of astragali radix, 5-8 g of rhizoma sparganii, 5-8 g of curcuma zedoary, 5-8 g of lumbricus, 5-8 g of herba lycopi, 5-8 g of fresh rhizoma alismatis, 3-5 g of gastrodia elata and 8-10 g of uncaria. The dosage form of the traditional Chinese medicine preparation can be any one dosage form in the pharmaceutical technology; and the preferable dosage form is decoction. The traditional Chinese medicine preparation for treating the cervical spondylosis can be prepared through the following steps of: a, placing all the medicines except for the uncaria into a pot and adding water to immerse all the medicines; decocting and boiling for 45 hours; and taking a medicine liquid; b, adding the uncaria into the residual medicines, adding water and decocting, wherein the step is the same as the step a; and c, mixing the medicine liquid obtained twice and concentrating to obtain the decoction. The traditional Chinese medicine preparation for treating the cervical spondylosis can be used for obviously improving the clinical symptoms of a patient, the operation is simple, and the medicine compliance of a patient is good, so that the aim of the invention is guaranteed.

Description

Be used to treat the Chinese medicine preparation of cervical spondylosis

Technical field

The invention belongs to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation of treating cervical spondylosis.

Background technology

Cervical spondylosis is claimed cervical spine syndrome again, is the general name that osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, cervical intervertebral disk are deviate from disease; It is a kind of illness of changing into the basis with degeneration pathology.Mainly due to cervical vertebra strain for a long time, hyperosteogeny, or prolapse of intervertebral disc, ligament thicken, and causes cervical vertebra spinal cord, nerve root or vertebral artery pressurized, causes a series of handicapped clinical syndromes.Show as intervertebral disc degradation itself and insecondary a series of pathological change thereof, like vertebra joint unstability, loosening; Vertebral pulp is given prominence to or is deviate from; Bony spur forms; The spinal canal stenosis of ligament plumpness and secondary etc. stimulate or have oppressed the tissues such as nerve root, spinal cord, vertebral artery and cervical region sympathetic nerve of vicinity, and cause the syndrome of various sings and symptoms.Can be divided into cervical spondylotic radiculopathy, vertebral artery type of cervical spondylosis and cervical spondylotic myelopathy.

The cervical spondylotic radiculopathy cardinal symptom has neck and shoulder part pain, numbness, and cervical region and occipitalia are ached and to upper limb radiation, Wry Neck or to strong tilt, after stretch, or the pain increased when Ipsilateral rotates.The innervation district dermal sensation of getting involved is gone down, paraesthesia, and cervical muscle is nervous, and obvious pain spot is arranged, distraction test (+), pressure head test (+).

Vertebral artery type of cervical spondylosis is because the cervical vertebra degenerative change causes cervical spinal canal or intervertebral foramina distortion, narrow; Stimulate the compressing vertebral artery; The outer dysequilibrium of keel; Cause vertebra one basilar artery insufficiency and cause that clinical manifestation is symptoms of cerebral ischemia such as cerebral vasospasm symptom such as headache, dizziness and dizzy, nauseating, tinnitus, blurring of vision, severe patient can occur one and cross the property faintness.Belong to categories such as the traditional Chinese medical science " headache ", " dizzy ", " arthromyodynia ", " stiffness of the nape ", " neck and shoulder pain ".

Cervical spondylotic myelopathy be cervical spinal canal narrow due to, be the maximum type of hazardness in the cervical spondylosis.Complicated clinical manifestation is main with the dyskinesia.The lighter's extremities aching pain weakness, instability of gait; Weight person's gatism and quadriplegia.It is " arthromyodynia " " myopathy " category of the traditional Chinese medical science.

Cervical spondylosis belongs to categories such as Chinese medical ' arthralgia syndrome ', " dizzy ", " rheumatism involving the bone ".Sui Chao Yuan Fang "to treat patients on the" wind weakness designate said:? Paralysis who wind cold dampness three gas hybrid, co-Bi clinical findings from this disease in the vacuity, treatment, taken to qi nourishing, carminative and cold, warm flow of qi, blood circulation basic rule is.

Western medicine can play auxiliary symptomatic treatment effect in the treatment of primary disease, can select to use analgesic, tranquilizer, vitamin (like B1, B12), and hospital administration can be selected for use: vasodilation and Chinese herbal medicine etc., the alleviation of symptoms has certain effect.The Chinese medicine aspect, still inefficacy preparation definite, that have no side effect is in the news out at present.

Summary of the invention

The Chinese medicine preparation that is used to treat cervical spondylosis that the purpose of this invention is to provide a kind of determined curative effect, standard criterion.

The technical scheme that the present invention adopts is following: be used to treat the Chinese medicine preparation of cervical spondylosis, it is characterized in that: the effective ingredient in every 100g preparation is processed by following crude medicinal materials:

Radix Angelicae Sinensis 5-8g, Rhizoma Chuanxiong 10-15g, Radix Puerariae 10-12g, Rhizoma Et Radix Notopterygii 8-10g, Radix Astragali 12-18g; Triangular 5-8g, Rhizoma Curcumae 5-8g, Pheretima 5-8g, Herba Lycopi 5-8g; Living Rhizoma Alismatis 5-8g, Rhizoma Gastrodiae 3-5g, Ramulus Uncariae Cum Uncis 8-10g, its dosage form can be said any dosage form on the pharmaceutics.Preferred dosage form is a decoction.

Further, the effective ingredient in every 100g preparation is processed by following crude medicinal materials:

Radix Angelicae Sinensis 6.5g, Rhizoma Chuanxiong 13g, Radix Puerariae 11g, Rhizoma Et Radix Notopterygii 9g, Radix Astragali 15g, triangular 6.5g, Rhizoma Curcumae 6.5g, Pheretima 6.5g, Herba Lycopi 6.5g, living Rhizoma Alismatis 6.5g, Rhizoma Gastrodiae 4g, Ramulus Uncariae Cum Uncis 9g.

The present invention can adopt following method preparation:

A. all medical materials except that Ramulus Uncariae Cum Uncis are placed pot, add water to and do not have crowd's medicine, decoct, keep boiling 45 minutes, taking liquid;

B. remain and add Ramulus Uncariae Cum Uncis in the medical material, decocte with water once more, method is with step a;

C. twice gained combining medicine concentrates, and makes decoction.

Decoction described in the present invention, precipitate with ethanol, step such as concentrate, be the common method of formulation art, part is to the greatest extent all handled in a usual manner.

The Chinese medicine with qi and blood, expel wind and cold, warm flow of qi, promoting blood circulation effect.Rhizoma Gastrodiae is gone into Liver Channel, and cerebral blood flow is increased, and vascular resistance descends, and has the abirritative effect, the kind numb limbs and tense tendons contracture of the limbs of controlling; The Ramulus Uncariae Cum Uncis relieving spasm to stop pain, arresting convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc.; Radix Puerariae is delivered, expelling pathogenic factors from muscles, relieving convulsion, specially controls stiff nape and back, can the up through sick institute of priming; Contain puerarin; Have blood vessel dilating and regulate the vestibule vegetative nerve function, improve the vertebra basilar arterial blood supply and eliminate the nerve root edema, relieve muscle spasms and the effect that improves little joint disorders; Radix Angelicae Sinensis benefiting QI and nourishing blood, numbness relieving and pain relieving contain volatile oil, have the effect of blood circulation promoting; Radix Astragali QI invigorating invigorating middle warmer consolidating superficial resistance has blood vessel dilating, improves the effect of blood circulation and blood flow increasing; Pheretima promoting blood circulation, sharp joint, repercussive stagnate, and treat arthralgia pain, contain the ground LONGSU, have thrombolytic effect; Rhizoma Chuanxiong dispels the wind, the meridian dredging, pain relieving, contains alkaloid (ligustrazine), has expansion of cerebral vascular, reduces the effect of vascular resistance, cerebral blood flow increasing amount and microcirculation improvement; Herba Lycopi, Rhizoma Alismatis promoting blood flow to regulate menstruation, inducing diuresis to remove edema have the effect of eliminating the nerve root edema; Triangular, Rhizoma Curcumae promoting blood circulation to disperse blood clots and relieves pain contain fat-soluble and water soluble ingredient, and the ability blood vessel dilating reduces the blood stickiness.Various drugs played a total of qi and blood, dispelling wind and cold, warm flow of qi and blood circulation effect.

The specific embodiment

Embodiment one

Preparation of medicaments

Get Radix Angelicae Sinensis 13g, Rhizoma Chuanxiong 26g, Radix Puerariae 22g, Rhizoma Et Radix Notopterygii 18g, Radix Astragali 30g, triangular 13g, Rhizoma Curcumae 13g, Pheretima 13g, Herba Lycopi 13g, living Rhizoma Alismatis 13g, Rhizoma Gastrodiae 8g places pot, adds water to not have crowd's medicine, decocts, and keeps boiling 45 minutes, taking liquid; Add Ramulus Uncariae Cum Uncis 18g, decocte with water once more keeps boiling 45 minutes, taking liquid; With twice combining medicine, concentrate, packing obtains the 200g medicament.

Embodiment two

Clinical trial

1, data and method

1.1 clinical data

This organizes 86 examples; Man's 37 examples; Woman's 49 examples, at 21～76 years old age, took the photograph c spine ap & lat in average 46 years old and diclinic position X-ray film shows: cervical vertebra all has pathologic change in various degree; Become 32 examples such as straight or anti-bow, vertebral body hyperosteogeny, narrowing of intervertebral space, the calcification of uncovertebral joint hypertrophy paxwax like physiologic radian and show that through CT examination cervical vertebra has hyperosteogeny in various degree, wherein 19 examples show that cervical intervertebral disk bulging in various degree is with outstanding.All meet the diagnostic criteria of cervical spondylosis in " disease of tcm diagnosis criterion of therapeutical effect ".

1.2 Therapeutic Method

Get the medicament 300ml of embodiment one every day, divide three times decoction being taken warmly, 7 days is a course of treatment.

2, efficacy assessment standard

Clinical research guideline and curative effect determinate standard with reference to new Chinese medicine treatment cervical spondylosis are drafted following criterion of therapeutical effect, cure: patient's clinical symptoms and sign disappearance, X-ray film are checked and are shown that the vertebral body regression do not see development; Produce effects: sings and symptoms disappears basically, does not influence normal work life; Effectively: sings and symptoms alleviates, and symptom is arranged after the fatigue, and it is influenced to work; Invalid: sings and symptoms does not have improvement even increases the weight of.

3, efficacy evaluation result

7～42 days this group patient treatment phases, average 27 days.By above-mentioned criterion of therapeutical effect evaluation curative effect, this group clinical cure 31 examples, produce effects 29 examples, effective 20 examples, invalid 6 examples.

To sum up: adopt this Chinese medicine preparation treatment cervical vertebra condition of disease obviously to improve patient's clinical symptoms, simple to operate, and the compliance of patient's medication is good, can prove the object of the invention.

Claims (4)

1. be used to treat the Chinese medicine preparation of cervical spondylosis, it is characterized in that: the effective ingredient in every 100g preparation is processed by following crude medicinal materials:

Radix Angelicae Sinensis 5-8g Rhizoma Chuanxiong 10-15g Radix Puerariae 10-12g

The triangular 5-8g of Rhizoma Et Radix Notopterygii 8-10g Radix Astragali 12-18g

The living Rhizoma Alismatis 5-8g of Rhizoma Curcumae 5-8g Pheretima 5-8g Herba Lycopi 5-8g Rhizoma Gastrodiae 3-5g Ramulus Uncariae Cum Uncis 8-10g

Its dosage form can be said any dosage form on the pharmaceutics.

2. Chinese medicine preparation as claimed in claim 1 is characterized in that: the effective ingredient in every 100g preparation is processed by following crude medicinal materials:

Radix Angelicae Sinensis 6.5g Rhizoma Chuanxiong 13g Radix Puerariae 11g

The triangular 6.5g of Rhizoma Et Radix Notopterygii 9g Radix Astragali 15g

The living Rhizoma Alismatis 6.5g of Rhizoma Curcumae 6.5g Pheretima 6.5g Herba Lycopi 6.5g Rhizoma Gastrodiae 4g Ramulus Uncariae Cum Uncis 9g.

3. according to claim 1 or claim 2 Chinese medicine preparation, it is characterized in that: its dosage form is a decoction.

4. Chinese medicine preparation as claimed in claim 3 is characterized in that: it makes through following method:

A. all medical materials except that Ramulus Uncariae Cum Uncis are placed pot, add water to and do not have crowd's medicine, decoct, keep boiling 45 minutes, taking liquid;

B. remain and add Ramulus Uncariae Cum Uncis in the medical material, decocte with water once more, method is with step a;

C. twice gained combining medicine concentrates, and makes decoction.