CN102657173B - 溴氯海因和二氯海因复方消毒片及其制备方法 - Google Patents
溴氯海因和二氯海因复方消毒片及其制备方法 Download PDFInfo
- Publication number
- CN102657173B CN102657173B CN201210158627.0A CN201210158627A CN102657173B CN 102657173 B CN102657173 B CN 102657173B CN 201210158627 A CN201210158627 A CN 201210158627A CN 102657173 B CN102657173 B CN 102657173B
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- CN
- China
- Prior art keywords
- bcdmh
- powder
- chlordantoin
- dimethyl hydantoin
- tablet
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- -1 DCDMH compound Chemical class 0.000 title claims abstract description 28
- 238000004659 sterilization and disinfection Methods 0.000 title abstract description 23
- 238000000034 method Methods 0.000 title abstract description 7
- OMJKWVKPIOIQDM-UHFFFAOYSA-N 3-bromo-1-chloroimidazolidine-2,4-dione Chemical compound ClN1CC(=O)N(Br)C1=O OMJKWVKPIOIQDM-UHFFFAOYSA-N 0.000 title 1
- PIEXCQIOSMOEOU-UHFFFAOYSA-N 1-bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione Chemical compound CC1(C)N(Br)C(=O)N(Cl)C1=O PIEXCQIOSMOEOU-UHFFFAOYSA-N 0.000 claims abstract description 45
- 239000000843 powder Substances 0.000 claims abstract description 22
- 229960004208 clodantoin Drugs 0.000 claims description 38
- VOGJJBHRUDVEFM-UHFFFAOYSA-N clodantoin Chemical compound CCCCC(CC)C1NC(=O)N(SC(Cl)(Cl)Cl)C1=O VOGJJBHRUDVEFM-UHFFFAOYSA-N 0.000 claims description 15
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 13
- 239000000460 chlorine Substances 0.000 claims description 13
- 229910052801 chlorine Inorganic materials 0.000 claims description 13
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 11
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 11
- 229910052794 bromium Inorganic materials 0.000 claims description 11
- 230000000249 desinfective effect Effects 0.000 claims description 11
- 239000002245 particle Substances 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 238000003825 pressing Methods 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 2
- 239000000470 constituent Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 19
- 230000001954 sterilising effect Effects 0.000 abstract description 5
- 230000009182 swimming Effects 0.000 abstract description 5
- 239000002699 waste material Substances 0.000 abstract description 5
- 238000009360 aquaculture Methods 0.000 abstract description 4
- 244000144974 aquaculture Species 0.000 abstract description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 3
- 239000008235 industrial water Substances 0.000 abstract description 3
- 231100000053 low toxicity Toxicity 0.000 abstract description 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- KEQGZUUPPQEDPF-UHFFFAOYSA-N 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione Chemical compound CC1(C)N(Cl)C(=O)N(Cl)C1=O KEQGZUUPPQEDPF-UHFFFAOYSA-N 0.000 abstract 1
- YIROYDNZEPTFOL-UHFFFAOYSA-N 5,5-Dimethylhydantoin Chemical compound CC1(C)NC(=O)NC1=O YIROYDNZEPTFOL-UHFFFAOYSA-N 0.000 abstract 1
- 230000003385 bacteriostatic effect Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 7
- 239000011812 mixed powder Substances 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- 238000005469 granulation Methods 0.000 description 4
- 230000003179 granulation Effects 0.000 description 4
- CUILPNURFADTPE-UHFFFAOYSA-N hypobromous acid Chemical compound BrO CUILPNURFADTPE-UHFFFAOYSA-N 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 239000000498 cooling water Substances 0.000 description 3
- 239000000645 desinfectant Substances 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 241000195493 Cryptophyta Species 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 2
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 description 2
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 2
- 239000005416 organic matter Substances 0.000 description 2
- JHJLBTNAGRQEKS-UHFFFAOYSA-M sodium bromide Chemical compound [Na+].[Br-] JHJLBTNAGRQEKS-UHFFFAOYSA-M 0.000 description 2
- YRIZYWQGELRKNT-UHFFFAOYSA-N 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione Chemical compound ClN1C(=O)N(Cl)C(=O)N(Cl)C1=O YRIZYWQGELRKNT-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 239000004155 Chlorine dioxide Substances 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000003619 algicide Substances 0.000 description 1
- SWLVFNYSXGMGBS-UHFFFAOYSA-N ammonium bromide Chemical compound [NH4+].[Br-] SWLVFNYSXGMGBS-UHFFFAOYSA-N 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000003139 biocide Substances 0.000 description 1
- 229940006460 bromide ion Drugs 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- VDQQXEISLMTGAB-UHFFFAOYSA-N chloramine T Chemical compound [Na+].CC1=CC=C(S(=O)(=O)[N-]Cl)C=C1 VDQQXEISLMTGAB-UHFFFAOYSA-N 0.000 description 1
- 239000012320 chlorinating reagent Substances 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 235000019398 chlorine dioxide Nutrition 0.000 description 1
- 125000001309 chloro group Chemical group Cl* 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 235000012055 fruits and vegetables Nutrition 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- 230000003641 microbiacidal effect Effects 0.000 description 1
- 229940124561 microbicide Drugs 0.000 description 1
- 239000002855 microbicide agent Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 239000012286 potassium permanganate Substances 0.000 description 1
- 229960001841 potassium permanganate Drugs 0.000 description 1
- 230000000452 restraining effect Effects 0.000 description 1
- MSFGZHUJTJBYFA-UHFFFAOYSA-M sodium dichloroisocyanurate Chemical compound [Na+].ClN1C(=O)[N-]C(=O)N(Cl)C1=O MSFGZHUJTJBYFA-UHFFFAOYSA-M 0.000 description 1
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 229950009390 symclosene Drugs 0.000 description 1
- 229960001479 tosylchloramide sodium Drugs 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Treatment Of Water By Oxidation Or Reduction (AREA)
Abstract
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Priority Applications (1)
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CN201210158627.0A CN102657173B (zh) | 2012-05-16 | 2012-05-16 | 溴氯海因和二氯海因复方消毒片及其制备方法 |
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CN201210158627.0A CN102657173B (zh) | 2012-05-16 | 2012-05-16 | 溴氯海因和二氯海因复方消毒片及其制备方法 |
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CN102657173A CN102657173A (zh) | 2012-09-12 |
CN102657173B true CN102657173B (zh) | 2014-04-23 |
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CN102899197B (zh) * | 2012-10-12 | 2014-06-25 | 河北鑫淘源环保科技有限公司 | 一种座便器清洁锭及其制作方法 |
CN115968889A (zh) * | 2021-11-16 | 2023-04-18 | 离享未来(天津)科技有限公司 | 一种复方二氯海因消毒剂的制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1430894A (zh) * | 2002-01-11 | 2003-07-23 | 中国石油天然气集团公司 | 一种含溴杀生剂-溴氯威 |
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CN100407923C (zh) * | 2005-12-19 | 2008-08-06 | 南京工业大学 | 一种杀菌消毒剂及其应用 |
CN101496521A (zh) * | 2008-01-29 | 2009-08-05 | 上海钟磊环保科技有限公司 | 一种活性可控二溴海因 |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1430894A (zh) * | 2002-01-11 | 2003-07-23 | 中国石油天然气集团公司 | 一种含溴杀生剂-溴氯威 |
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Owner name: HEBEI XINTAOYUAN ENVIRONMENTAL PROTECTION TECHNOLO Free format text: FORMER OWNER: HEBEI YAGUANG FINE CHEMICAL CO., LTD. Effective date: 20131015 |
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C41 | Transfer of patent application or patent right or utility model | ||
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Effective date of registration: 20131015 Address after: North of Quzhou County Hebei province 057250 Handan modern new industrial park Applicant after: Hebei Xintaoyuan Environment Protection Technology Co., Ltd. Address before: 057250 Hebei city of Handan province in Quzhou County in Quzhou City north of Wei Luxi Applicant before: Hebei Yaguang Fine Chemical Co., Ltd. |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CP01 | Change in the name or title of a patent holder | ||
CP01 | Change in the name or title of a patent holder |
Address after: 057250 North District of Quzhou Modern New Industrial Park, Handan City, Hebei Province Patentee after: Hebei xintaoyuan Pharmaceutical Technology Co.,Ltd. Address before: 057250 North District of Quzhou Modern New Industrial Park, Handan City, Hebei Province Patentee before: HEBEI XINTAOYUAN ENVIRONMENT PROTECTION TECHNOLOGY Co.,Ltd. |
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TR01 | Transfer of patent right | ||
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Effective date of registration: 20211110 Address after: 056000 Economic Development Zone, Feixiang District, Handan City, Hebei Province (Beijing Tianjin New Material Industrial Park) Patentee after: Hebei Lishi Chemical Technology Co., Ltd Address before: 057250 North District of modern new industrial park, Quzhou County, Handan City, Hebei Province Patentee before: Hebei xintaoyuan Pharmaceutical Technology Co., Ltd |