CN102609981A - Method for constructing three-dimensional brain model - Google Patents

Method for constructing three-dimensional brain model Download PDF

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CN102609981A
CN102609981A CN2012100172282A CN201210017228A CN102609981A CN 102609981 A CN102609981 A CN 102609981A CN 2012100172282 A CN2012100172282 A CN 2012100172282A CN 201210017228 A CN201210017228 A CN 201210017228A CN 102609981 A CN102609981 A CN 102609981A
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image
model
brain
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CN102609981B (en
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杨治荣
郭智霖
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Abstract

The invention discloses a method for constructing a three-dimensional brain model, comprising the steps of using a magnetic resonance skull sagittal thin layer to image; obtaining data with a T1DICOM format as a source material; transforming the source material into an image with a bmp format; separating a target image from the image with the bmp format; introducing the obtained target image to a three-dimensional reconstruction software; setting space position in an empty manner, producing a mask and constructing a crude three-dimensional model; converting the crude three-dimensional model into a low surface target model by means of surface lowering processing; finally, connecting the low surface target model and the original data with the T1DICOM format to obtain the three-dimensional brain model. When the three-dimensional brain model constructed by the invention and the original skull magnetic resonance target picture are verified, the contour line of the three-dimensional brain model is nicely consistent with the edge of the original image with the T1DICOM format.

Description

Make up the method for three-dimensional brain model
Technical field
The present invention relates to a kind of method of the 3D of structure numeral brain model, relate in particular to a kind of method of the tomoscan picture being carried out the three-dimensional brain model of three-dimensional reorganization formation.
Background technology
Nervous System Anatomy is a complicated medical science form science of the various space structure of content; Particularly basis cranii and brain dissect abstract hard to understand be the teaching and clinical practice in outstanding problem and where the shoe pinches; Traditional method is to utilize two-dimentional means such as chalk, blackboard, teaching material, wall chart, projection to explain, and carries out the sample teaching then and cultivates the doctor.Clinically, cerebral cortex and brain DEEP STRUCTURE are the basic positions that neurosurgery is organized work, but cerebral cortex and deep nuclei space structure thereof are very complicated; Be difficult to clear assurance exactly; Therefore the neurosurgeon usually uses head two-dimensional scan planar graph information, according to the brain anatomical knowledge, and abstract reconstruct brain three-dimensional information; In a single day deviation appears in reconstruct, will form mistake and risk.
Therefore, make up the visual brain model of 3-dimensional digital that fidelity is high, the error probability is little, help neurosurgery and select rational operation pathway, effectively instruct the neurosurgery clinical practice, also help the teaching of medical colleges and schools.
People such as Wei Na are in " based on the brain model three-dimensional rebuilding method research of Visualization Toolki " (Chinese rehabilitation theory and practice; 2005 the 11st the 3rd phases of volume; 167 ~ 169 pages) measurement data based on CT is disclosed in the literary composition; Utilize visualization tool bag Visualization Toolki to combine VC to realize medical image three-dimensional visualization, rebuild head model; On this basis, Zhang Shuli etc. have visually carried out detailed introduction to what utilize that Visualization Toolki carries out the CT image in " utilize VTK realize medicine CT image three-dimensional visualization " (Qiqihar Medical College's journal, the 9th phase of 2006 phases) literary composition.
But brain is different with head, and brain is a part of structure of head.Method with rebuilding head can not built brain.Because it is the difficulty that said method can't overcome that brain is separated from head.Therefore moreover as far as all brain structures, head MRI (magnetic resonance imaging) is much clear than head CT, need be based on the construction method of the three-dimensional brain model of MRI image.
Summary of the invention
In order to solve the problem of utilizing the three-dimensional brain model of MRI imaging reconstruction, the invention provides a kind of method that makes up three-dimensional brain model, based on the MRI imaging, utilize the three-dimensional brain model of computing machine recombination to construct.
Therefore the purpose of this invention is to provide a kind of method that makes up three-dimensional brain model, step comprises:
Step 1 selects institute will carry out the brain of reconstructing three-dimensional model, and magnetic resonance head sagittal plain thin layer forms images, and obtains T 1The image of the raw data of DICOM form and bmp form;
Step 2; (brain) target image is separated from the head image of bmp form; Through importing module the brain target image that is separated is imported the dimensional orientation setting module in the computing machine in order successively; Set the dimensional orientation of picture, make the dimensional orientation of picture corresponding with the real space position;
Step 3, processor operations image segmentation module becomes to cut apart tissue with the imaging processing that configures the orientation and covers plate, and replaces morphology opening operation and closed operation through the procedure operation computing module, cuts apart tiny uneven in the edge of tissue illiteracy plate with elimination;
Step 4, the three-dimensional reconstruction module is carried out three-dimensional computing, carries out three-dimensional reconstruction and obtains three-dimensional roughcast cutting apart tissue, and through converter the mode of three-dimensional roughcast with visual image derived;
Step 5 imports second computing module with three-dimensional roughcast, creates the bottom surface rectangular parallelepiped of volume greater than object module, does Boolean calculation with object module then and gets common factor, obtains the bottom surface object module;
Step 6 imports relating module with the bottom surface object module, simultaneously with magnetic resonance image data (above-mentioned T 1The DICOM data) import relating module, utilize the method for multiaspect pinup picture to carry out data association, obtain the visualization of 3 d brain model, and show through display device.
Wherein, " association " shown in refers to the multiaspect pinup picture.
Wherein, in the said magnetic resonance head sagittal plain thin layer image-forming step, bed thickness is preferably 0.1 ~ 1.0mm, and more preferably 0.4 ~ 1.0mm most preferably is 0.5mm; Layer is apart from being preferably 0.90 ~ 1.05mm, and more preferably 0.90 ~ 1.0mm most preferably is 0.95mm.
The number of plies of said magnetic resonance head sagittal plain thin layer imaging is preferably >=dip stratum, more elects 161 ~ 176 layers as.
The visualization of 3 d brain model that obtains in the step 6 through display device respectively in the axle position, crown position and sagittal plain show that perhaps any orientation in axle position, crown position and sagittal plain shows.
A kind of preferred embodiment of the method for the three-dimensional brain model of above-mentioned structure according to the present invention through the mimics software importing dimensional orientation setting module that will form images, and passes through this software set dimensional orientation in the step 2.
Wherein, the dimensional orientation position of setting is: the orientation in virtual is selected according to true bearing.
The another kind of preferred embodiment of the method for the three-dimensional brain model of above-mentioned structure according to the present invention can use 3DS-MaX software creation bottom surface rectangular parallelepiped and carries out Boolean calculation and get common factor in the step 5.But also can use other software or program with identical function.
In the step 6, also can use 3DS-MaX software to import bottom surface object module and magnetic resonance image data, carry out data association.But also can use other software or program with identical function.
In the method for the three-dimensional brain model of structure that the present invention is above-mentioned, after constructing three-dimensional brain model, can also carry out colored drawing and play up, to obtain better bandwagon effect.
The present invention makes up that the method for three-dimensional brain model adopts is that outline line with the multilayer two-dimension image connects with dough sheet; Constitute body surface, become solid, realize that two dimension becomes three-dimensional by the plane; Carry out aftertreatment then, the visualization of 3 d brain model is shown through display device.Through comparing and can find with original head MRI picture, the range line profile and the MRI picture of the three-dimensional brain model that the present invention makes up are very identical.
In sum, the present invention has constructed the stimulated three-dimensional image of the 3-D cranium brain dissection with good visibility through said method, has improved efficiency of teaching greatly and has guaranteed quality of medical care.
Description of drawings
The three-dimensional brain model photo that Fig. 1 cuts for the brain that makes up in an embodiment of the present invention;
The three-dimensional brain model photo that Fig. 2 cuts for the brain that makes up in an embodiment of the present invention;
Fig. 3 cuts three-dimensional brain model photo for the brain and the head of the said brain of Fig. 1 that makes up in an embodiment of the present invention;
Fig. 4 is the telocoele model background in an embodiment of the present invention;
Fig. 5 is the three-dimensional brain model photo of the telocoele that makes up in an embodiment of the present invention;
Fig. 6 is the three-dimensional brain model photo of the side brain stripping and slicing that makes up in an embodiment of the present invention;
Fig. 7 is the brain and head incision three-dimensional model photo of the said brain of Fig. 2 that makes up in an embodiment of the present invention;
Fig. 8 is the three-dimensional full brain model photo of the band portion skull that makes up in an embodiment of the present invention;
(when not giving data association) skeleton diagram that the three-dimensional full brain model that Fig. 9 makes up for the embodiment of the invention 8 cuts arbitrarily.
Embodiment
The invention provides a kind of method that makes up three-dimensional brain model, step comprises:
Step 1 is selected head magnetic resonance sagittal plain thin layer imaging gained T 1The data of DICOM form are source book, source book are converted into the head image of bmp form;
Step 2; Target image (brain) is separated from the head image of bmp form; Through importing module said target image is imported the dimensional orientation setting module in the computing machine in order successively, set the dimensional orientation of picture, make the dimensional orientation of picture corresponding with the real space position;
Step 3, processor operations image segmentation module becomes to cut apart tissue with the Flame Image Process that configures the orientation and covers plate, and replaces morphology opening operation and closed operation through the procedure operation computing module, cuts apart tiny uneven in the edge of tissue illiteracy plate with elimination;
Step 4, the three-dimensional reconstruction module is carried out three-dimensional computing, carries out three-dimensional reconstruction and obtains three-dimensional roughcast cutting apart tissue, and through converter the mode of three-dimensional roughcast with visual image derived;
Step 5 imports second computing module with three-dimensional roughcast, creates the bottom surface rectangular parallelepiped of volume greater than object module, does Boolean calculation with object module then and gets common factor, obtains the bottom surface object module;
Step 6 imports relating module with the bottom surface object module, simultaneously with magnetic resonance image data (above-mentioned T 1The DICOM data) import relating module, utilize the method for multiaspect pinup picture to carry out data association, obtain the visualization of 3 d brain model, and show through display device.
Through specific embodiment, the method that the present invention is made up three-dimensional brain model is carried out detailed introduction and description below, so that understand the present invention better, but should be understood that following embodiment does not limit the scope of the invention.
Embodiment 1
Step 1
34 years old healthy male volunteers, the imaging of 1.5T magnetic resonance head sagittal plain thin layer, gained T 1DICOM form raw data is the data of this research.Image-forming condition: bed thickness 0.8mm, layer is apart from 0.95mm; W * H=256 * 256; 170 layers of the numbers of plies.
The MRI pre-service is become the bmp form.
Step 2
Graphics workstation: Core central processing unit, internal memory, color monitor, 1024 * 768 resolution, storage unit; Windows XP operating system, 3DS-MaX11.0, mimics8.0 and related software thereof.
The brain target separation of images is come out; Be selected from the bmp format-pattern of people's part brain; Import mimics software; The bmp format-pattern of pre-service gained is imported appointment figure layer in order successively,, make the brain in the picture corresponding with the real space position in the locus that the dimensional orientation setting module is set through the dimensional orientation of dimensional orientation setting module setting picture.
Step 3
Central processing unit operation image segmentation module is carried out split image, and background is a black, generates and cuts apart tissue illiteracy plate, sets pixel parameter then; Through procedure operation computing module hocket morphology opening operation and closed operation, to eliminate tiny rough and uneven in surface in edge.
Step 4
Then carry out three-dimensional computing, it is high setting the reconstruction quality of optimizing, and carries out three-dimensional reconstruction to cutting apart tissue.Export the STL form then and be kept at storage unit, cut apart the English name named file of tissue, for example brain.stl.Accomplished the structure of three-dimensional roughcast to this.
Step 5
It is too many to rebuild the roughcast face number that generates, and travelling speed is unfavorable for playing up slowly, more can't accomplish pinup picture.Need handle the model face that falls.
Three-dimensional roughcast is imported second computing module through 3DS-MaX software, create the bottom surface rectangular parallelepiped of volume, do Boolean calculation with object module then and get common factor, obtain the bottom surface object module greater than object module.Still preserve after the satisfaction with the STL form.
Step 6
Through 3DS-MaX software the bottom surface object module is imported relating module, simultaneously with magnetic resonance picture T 1The DICOM raw data imports relating module, utilizes the method for multiaspect pinup picture to carry out data association, obtains the visualization of 3 d brain model, and shows through display device.
The three-dimensional stereo model that Fig. 1 cuts for the brain that makes up in the present embodiment.
Embodiment 2
Step 1
34 years old healthy male volunteers, the imaging of 1.5T magnetic resonance head sagittal plain thin layer, gained T 1DICOM form raw data is the data of this research.Image-forming condition: bed thickness 0.8mm, layer is apart from 0.95mm; W * H=256 * 256; 170 layers of the numbers of plies.
The MRI pre-service is become the bmp form.
Step 2
Graphics workstation: Core central processing unit, internal memory, color monitor, 1024 * 768 resolution, storage unit; Windows XP operating system, 3DS-MaX11.0, mimics8.0 and related software thereof.
Be selected from human brain and remove the MRI of the part behind the embodiment 1 said position; Import mimics software; The bmp format-pattern of pre-service gained is imported appointment figure layer in order successively; Set the dimensional orientation of picture, make the brain in the picture corresponding with the real space position, be written into the space position parameter of setting then in the locus that the dimensional orientation setting module is set.
Step 3
Carry out split image, background is a black, generates to cut apart tissue illiteracy plate, sets pixel parameter then; Hocket morphology opening operation and closed operation are to eliminate tiny rough and uneven in surface in edge.
Step 4
Then carry out three-dimensional computing, it is high setting the reconstruction quality of optimizing, and carries out three-dimensional reconstruction to cutting apart tissue.Export the STL form then and be kept at storage unit, cut apart the English name named file of tissue, for example brain.stl.Accomplished the structure of three-dimensional roughcast to this.
Step 5
It is too many to rebuild the roughcast face number that generates, and travelling speed is unfavorable for playing up slowly, more can't accomplish pinup picture.Need handle the model face that falls.
Three-dimensional roughcast is imported second computing module through 3DS-MaX software, create the bottom surface rectangular parallelepiped of volume, do Boolean calculation with object module then and get common factor, obtain the bottom surface object module greater than object module.Still preserve after the satisfaction with the STL form.
Step 6
Through 3DS-MaX software the bottom surface object module is imported relating module, simultaneously with magnetic resonance picture T 1The DICOM raw data imports relating module, utilizes the method for multiaspect pinup picture to carry out data association, obtains the visualization of 3 d brain model, and shows through display device.
The three-dimensional stereo model that Fig. 2 cuts for the brain that makes up in the present embodiment.
Embodiment 3
Step 1
34 years old healthy male volunteers, the imaging of 1.5T magnetic resonance head sagittal plain thin layer, gained T 1DICOM form raw data is the data of this research.Image-forming condition: bed thickness 0.8mm, layer is apart from 0.95mm; W * H=256 * 256; 170 layers of the numbers of plies.
The MRI pre-service is become the bmp form.
Step 2
Graphics workstation: Core central processing unit, internal memory, color monitor, 1024 * 768 resolution, storage unit; Windows XP operating system, 3DS-MaX11.0, mimics8.0 and related software thereof.
The MRI that is selected from human brain embodiment 1 said position and comprises the part of the head that surrounds this part; Import mimics software; The bmp format-pattern of pre-service gained is imported appointment figure layer in order successively; Through the dimensional orientation of dimensional orientation setting module setting picture, make the brain in the picture corresponding with the real space position in the locus that the dimensional orientation setting module is set, be written into the space position parameter of setting then.
Step 3
Central processing unit operation image segmentation module is carried out split image, and background is a black, generates and cuts apart tissue illiteracy plate, sets pixel parameter then; Through procedure operation computing module hocket morphology opening operation and closed operation, to eliminate tiny rough and uneven in surface in edge.
Step 4
Then carry out three-dimensional computing, it is high setting the reconstruction quality of optimizing, and carries out three-dimensional reconstruction to cutting apart tissue.Export the STL form then and be kept at storage unit, cut apart the English name named file of tissue, for example brain.stl.Accomplished the structure of three-dimensional roughcast to this.
Step 5
It is too many to rebuild the roughcast face number that generates, and travelling speed is unfavorable for playing up slowly, more can't accomplish pinup picture.Need handle the model face that falls.
Three-dimensional roughcast is imported second computing module through 3DS-MaX software, create the bottom surface rectangular parallelepiped of volume, do Boolean calculation with object module then and get common factor, obtain the bottom surface object module greater than object module.Still preserve after the satisfaction with the STL form.
Step 6
Through 3DS-MaX software the bottom surface object module is imported relating module, simultaneously with magnetic resonance picture T 1The DICOM raw data imports relating module, utilizes the method for multiaspect pinup picture to carry out data association, obtains the visualization of 3 d brain model, and shows through display device.
The three-dimensional stereo model that Fig. 3 cuts for the brain that has head that makes up in the present embodiment, the outward flange white portion is skull and scalp.
Embodiment 4
Step 1
34 years old healthy male volunteers, the imaging of 1.5T magnetic resonance head sagittal plain thin layer, gained T 1DICOM form raw data is the data of this research.Image-forming condition: bed thickness 0.8mm, layer is apart from 0.95mm; W * H=256 * 256; 170 layers of the numbers of plies.
The MRI pre-service is become the bmp form.
Step 2
Graphics workstation: Core central processing unit, internal memory, color monitor, 1024 * 768 resolution, storage unit; Windows XP operating system, 3DS-MaX11.0, mimics8.0 and related software thereof.
Be selected from the MRI of human brain telocoele; Import mimics software; The bmp format-pattern of pre-service gained is imported appointment figure layer in order successively; Set the dimensional orientation of picture, make the brain in the picture corresponding with the real space position, be written into the space position parameter of setting then in the locus that the dimensional orientation setting module is set.
Step 3
Carry out split image, background is a black, generates to cut apart tissue illiteracy plate, sets pixel parameter then; Hocket morphology opening operation and closed operation are to eliminate tiny rough and uneven in surface in edge.
Step 4
Then carry out three-dimensional computing, it is high setting the reconstruction quality of optimizing, and carries out three-dimensional reconstruction to cutting apart tissue.Export the STL form then and be kept at storage unit, cut apart the English name named file of tissue, for example brain.stl.Accomplished the structure of three-dimensional roughcast to this.
Step 5
Three-dimensional roughcast is imported second computing module through 3DS-MaX software, create the bottom surface rectangular parallelepiped of volume, do Boolean calculation with object module then and get common factor, obtain the bottom surface object module greater than object module.Still preserve after the satisfaction with the STL form.
Step 6
Through 3DS-MaX software the bottom surface object module is imported relating module, simultaneously with magnetic resonance picture T 1The DICOM raw data imports relating module, utilizes the method for multiaspect pinup picture to carry out data association, obtains the visualization of 3 d brain model, and shows through display device.
Fig. 4 for make up in the present embodiment do not carry out data association the time the background of telocoele model; The telocoele three-dimensional stereo model of Fig. 5 for making up in the present embodiment.
Embodiment 5
Step 1
34 years old healthy male volunteers, the imaging of 1.5T magnetic resonance head sagittal plain thin layer, gained T 1DICOM form raw data is the data of this research.Image-forming condition: bed thickness 0.8mm, layer is apart from 0.95mm; W * H=256 * 256; 170 layers of the numbers of plies.
The MRI pre-service is become the bmp form.
Step 2
Graphics workstation: Core central processing unit, internal memory, color monitor, 1024 * 768 resolution, storage unit; Windows XP operating system, 3DS-MaX11.0, mimics8.0 and related software thereof.
Be selected from the MRI of human brain telocoele part stripping and slicing; Import mimics software; The bmp format-pattern of pre-service gained is imported appointment figure layer in order successively; Set the dimensional orientation of picture, make the brain in the picture corresponding with the real space position, be written into the space position parameter of setting then in the locus that the dimensional orientation setting module is set.
Step 3
Carry out split image, background is a black, generates to cut apart tissue illiteracy plate, sets pixel parameter then; Hocket morphology opening operation and closed operation are to eliminate tiny rough and uneven in surface in edge.
Step 4
Then carry out three-dimensional computing, it is high setting the reconstruction quality of optimizing, and carries out three-dimensional reconstruction to cutting apart tissue.Export the STL form then and be kept at storage unit, cut apart the English name named file of tissue, for example brain.stl.Accomplished the structure of three-dimensional roughcast to this.
Step 5
Three-dimensional roughcast is imported second computing module through 3DS-MaX software, create the bottom surface rectangular parallelepiped of volume, do Boolean calculation with object module then and get common factor, obtain the bottom surface object module greater than object module.Still preserve after the satisfaction with the STL form.
Step 6
Through 3DS-MaX software the bottom surface object module is imported relating module, simultaneously with magnetic resonance picture T 1The DICOM raw data imports relating module, utilizes the method for multiaspect pinup picture to carry out data association, obtains the visualization of 3 d brain model, and shows through display device.
Fig. 6 makes up telocoele stripping and slicing three-dimensional stereo model in the present embodiment.
Embodiment 6
Step 1
34 years old healthy male volunteers, the imaging of 1.5T magnetic resonance head sagittal plain thin layer, gained T 1DICOM form raw data is the data of this research.Image-forming condition: bed thickness 0.8mm, layer is apart from 0.95mm; W * H=256 * 256; 170 layers of the numbers of plies.
The MRI pre-service is become the bmp form.
Step 2
Graphics workstation: Core central processing unit, internal memory, color monitor, 1024 * 768 resolution, storage unit; Windows XP operating system, 3DS-MaX11.0, mimics8.0 and related software thereof.
The MRI that is selected from embodiment 2 said human brain parts and surrounds this part head; Import mimics software; The bmp format-pattern of pre-service gained is imported appointment figure layer in order successively; Set the dimensional orientation of picture, make the brain in the picture corresponding with the real space position, be written into the space position parameter of setting then in the locus that the dimensional orientation setting module is set.
Step 3
Carry out split image, background is a black, generates to cut apart tissue illiteracy plate, sets pixel parameter then; Hocket morphology opening operation and closed operation are to eliminate tiny rough and uneven in surface in edge.
Step 4
Then carry out three-dimensional computing, it is high setting the reconstruction quality of optimizing, and carries out three-dimensional reconstruction to cutting apart tissue.Export the STL form then and be kept at storage unit, cut apart the English name named file of tissue, for example brain.stl.Accomplished the structure of three-dimensional roughcast to this.
Step 5
Three-dimensional roughcast is imported second computing module through 3DS-MaX software, create the bottom surface rectangular parallelepiped of volume, do Boolean calculation with object module then and get common factor, obtain the bottom surface object module greater than object module.Still preserve after the satisfaction with the STL form.
Step 6
Through 3DS-MaX software the bottom surface object module is imported relating module, simultaneously with magnetic resonance picture T 1The DICOM raw data imports relating module, utilizes the method for multiaspect pinup picture to carry out data association, obtains the visualization of 3 d brain model, and shows through display device.
Fig. 7 makes up the part brain of side and the three-dimensional stereo model of head in the present embodiment, among the figure, the outer white border zone is a skull.
Embodiment 7
Step 1
34 years old healthy male volunteers, the imaging of 1.5T magnetic resonance head sagittal plain thin layer, gained T 1DICOM form raw data is the data of this research.Image-forming condition: bed thickness 0.8mm, layer is apart from 0.95mm; W * H=256 * 256; 170 layers of the numbers of plies.
The MRI pre-service is become the bmp form.
Step 2
Graphics workstation: Core central processing unit, internal memory, color monitor, 1024 * 768 resolution, storage unit; Windows XP operating system, 3DS-MaX11.0, mimics8.0 and related software thereof.
Be selected from the MRI of human brain and part head; Import mimics software; The bmp format-pattern of pre-service gained is imported appointment figure layer in order successively; Set the dimensional orientation of picture, make the brain in the picture corresponding with the real space position, be written into the space position parameter of setting then in the locus that the dimensional orientation setting module is set.
Step 3
Carry out split image, background is a black, generates to cut apart tissue illiteracy plate, sets pixel parameter then; Hocket morphology opening operation and closed operation are to eliminate tiny rough and uneven in surface in edge.
Step 4
Then carry out three-dimensional computing, it is high setting the reconstruction quality of optimizing, and carries out three-dimensional reconstruction to cutting apart tissue.Export the STL form then and be kept at storage unit, cut apart the English name named file of tissue, for example brain.stl.Accomplished the structure of three-dimensional roughcast to this.
Step 5
Three-dimensional roughcast is imported second computing module through 3DS-MaX software, create the bottom surface rectangular parallelepiped of volume, do Boolean calculation with object module then and get common factor, obtain the bottom surface object module greater than object module.Still preserve after the satisfaction with the STL form.
Step 6
Through 3DS-MaX software the bottom surface object module is imported relating module, simultaneously with magnetic resonance picture T 1The DICOM raw data imports relating module, utilizes the method for multiaspect pinup picture to carry out data association, obtains the visualization of 3 d brain model, and shows through display device.
Fig. 8 is the three-dimensional full brain model photo of the band portion skull that makes up in the present embodiment, and wherein, 2 is head, and 1 is brain; Fig. 9 (when not giving data association) skeleton diagram for making up that three-dimensional full brain model cuts arbitrarily in the present embodiment.
Original head MRI Target Photo and model structure compare, and picture and model are very identical as a result.Explain that the method for the invention is the method for the three-dimensional brain stereoscopic model of a kind of desirable structure.
More than specific embodiment of the present invention is described in detail, but it is just as example, the present invention is not restricted to the specific embodiment of above description.To those skilled in the art, any equivalent modifications that the present invention is carried out with substitute also all among category of the present invention.Therefore, not breaking away from impartial conversion and the modification of being done under the spirit and scope of the present invention, all should contain within the scope of the invention.

Claims (7)

1. method that makes up three-dimensional brain model is characterized in that step comprises:
Step 1 selects institute will carry out the brain of reconstructing three-dimensional model, and magnetic resonance head sagittal plain thin layer forms images, and obtains T 1The image of the raw data of DICOM form and bmp form;
Step 2; Target image is separated from the head image of bmp form; Through importing module target image is imported the dimensional orientation setting module in the computing machine in order successively, set the dimensional orientation of picture, make the dimensional orientation of picture corresponding with the real space position;
Step 3, processor operations image segmentation module becomes to cut apart tissue with the imaging processing that configures the orientation and covers plate, and replaces morphology opening operation and closed operation through the procedure operation computing module, cuts apart tiny uneven in the edge of tissue illiteracy plate with elimination;
Step 4, the three-dimensional reconstruction module is carried out three-dimensional computing, carries out three-dimensional reconstruction and obtains three-dimensional roughcast cutting apart tissue, and through converter the mode of three-dimensional roughcast with visual image derived;
Step 5 imports second computing module with three-dimensional roughcast, creates the bottom surface rectangular parallelepiped of volume greater than object module, does Boolean calculation with object module then and gets common factor, obtains the bottom surface object module;
Step 6 imports relating module with the bottom surface object module, simultaneously with magnetic resonance picture T 1The DICOM raw data imports relating module, utilizes the method for multiaspect pinup picture to carry out data association, obtains the visualization of 3 d brain model, and shows through display device.
2. the method for the three-dimensional brain model of structure according to claim 1 is characterized in that, in the said magnetic resonance head sagittal plain thin layer image-forming step, and bed thickness 0.1 ~ 1.0mm, layer is apart from 0.90 ~ 1.05mm.
3. the method for the three-dimensional brain model of structure according to claim 1 is characterized in that, the three-dimensional brain model that obtains in the step 6 through display device respectively in the axle position, crown position and sagittal plain show.
4. the method for the three-dimensional brain model of structure according to claim 1 is characterized in that, will form images through mimics software in the step 2 imports the dimensional orientation setting module, and through this software set dimensional orientation.
5. the method for the three-dimensional brain model of structure according to claim 4 is characterized in that, the dimensional orientation location parameter of setting is: layer is apart from equaling magnetic resonance imaging layer distance.
6. the method for the three-dimensional brain model of structure according to claim 1 is characterized in that, uses 3DS-MaX software creation bottom surface rectangular parallelepiped in the step 5 and carries out Boolean calculation and get common factor.
7. the method for the three-dimensional brain model of structure according to claim 1 is characterized in that, in the step 6, uses 3DS-MaX software to import bottom surface object module and magnetic resonance image data, carries out data association.
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CN103729875A (en) * 2013-12-09 2014-04-16 深圳先进技术研究院 Method and system for reconstructing three-dimensional left ventricular profile of cardiac magnetic resonance image
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