CN102608336A - Disposable transfusion and cross matching experiment combiner - Google Patents

Disposable transfusion and cross matching experiment combiner Download PDF

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Publication number
CN102608336A
CN102608336A CN2011100217931A CN201110021793A CN102608336A CN 102608336 A CN102608336 A CN 102608336A CN 2011100217931 A CN2011100217931 A CN 2011100217931A CN 201110021793 A CN201110021793 A CN 201110021793A CN 102608336 A CN102608336 A CN 102608336A
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China
Prior art keywords
test tube
cross matching
application
matching experiment
transfusion
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CN2011100217931A
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CN102608336B (en
Inventor
刘大基
袁卫东
陈卫红
程风华
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刘大基
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Priority to CN201110021793.1A priority Critical patent/CN102608336B/en
Priority to PCT/CN2011/002082 priority patent/WO2012097494A1/en
Priority to CN2011800434378A priority patent/CN103299194A/en
Publication of CN102608336A publication Critical patent/CN102608336A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6009General characteristics of the apparatus with identification means for matching patient with his treatment, e.g. to improve transfusion security

Abstract

The invention relates to medical experimental equipment and discloses a disposable transfusion and cross matching experiment combiner, which is provided with a small transparent plastic test tube. The upper opening of the small test tube is in butt joint with two sample adding tubes simultaneously, and the upper part of the small test tube is in fork connection with a transparent plastic film bag by a small material tube. The disposable transfusion and cross matching experiment combiner solves the problems that as the conventional transfusion and cross matching experiment is not supplied with special instruments, the operation with the conventional test tube is very complicated and trivial and easy to have errors. The disposable transfusion and cross matching experiment combiner is mainly used for cross matching experiments on patients subjected to transfusion in various hospital transfusion departments, center blood stations, clinical laboratories and the like.

Description

Disposable blood transfusion cross matching experiment combiner
(1) technical field: the present invention relates to medical experiment equipment, especially a kind of disposable blood transfusion cross matching experiment combiner.
(2) background technology: up to the present; It all is the principles according to safe transfusion that hospitals at different levels Blood Transfusion Dept. will be done blood transfusion cross matching experiment; Application abo blood group and RH blood group be the blood source of homotype (need transfuse blood then must seek the blood donor of the A type RH positive like A type RH positive patient) mutually; Blood donor and receptor's blood cell and serum are carried out Fen Li ﹑ respectively cross one another and be allowed to condition at reaction in test tube and observe its haemolysis agglutination phenomenon again, can judgement implement safe transfusion, promptly carries out the cross matching experiment.In the prior art; Blood transfusion cross matching experiment does not also still have special implement; Normally adopt common test tube to experimentize; This experiment is like the only defeated person-portion blood of a patient, and then they answer ﹑ two test tubes of Qu Zhu to add respectively: receptor's serum+blood donor's blood cell (person in charge): receptor's blood cell+blood donor's serum (inferior pipe).25~30 ℃; Centrifugal taking-up visual inspection in 5~10 minutes has or not haemolysis and agglutination phenomenon; Blood splashes on the slide and has or not agglutination phenomenon with microscopic examination after will pitching again; Last ﹑ the pipe of Zhu of Baoing has or not haemolysis and agglutination phenomenon, conclusion " to conform to " or " not conforming to ", judges the blood that could import this blood donor.
If the receptor needs under the situation of a large amount of blood transfusion (more than two person-portions) blood donor's blood, the cross matching experiment of being done before its blood transfusion is just more complicated.For example y-bend is once six test tubes of needs (all will carry out the cross matching experiment between because of every blood donor and receptor and between every blood donor); If the receptor needs trident for the moment; That wants the twelve earthly branches test tube; Add blood cell and serum the receptor from numbering the application of sample repeated multiple times, repeatedly (only this task operating of application of sample person adds blood cell and serum respectively once for every test tube with sample injector, and then the twelve earthly branches test tube is wanted application of sample 24 times at a distance from a position application of sample; Be responsible for and time pipe but also will be added to blood cell and serum by the mode of pairing dislocation; It is thus clear that its operation is very complicated loaded down with trivial details), therefore need multidigit blood supply liquid, this cross-over experiment whole process is more complicated loaded down with trivial details and be prone to make mistakes.
(3) summary of the invention: the object of the invention will solve existing blood transfusion cross matching experiment does not exactly still have special implement; Adopt common test tube to experimentize; Operate very complicated loaded down with trivial detailsly, and the problem of easy error provides a kind of disposable blood transfusion cross matching experiment combiner.
Concrete scheme of the present invention is: be designed with the transparent plastic small test tube, it is characterized in that: suitable for reading at small test tube simultaneously to being connected to two application of sample pipes, and through small powder pipe fork-join one transparent plastic film capsule is arranged on the top of small test tube.
Two application of sample pipes are the shaping one with small test tube or adopt helicitic texture to dock or the seccotine butt joint described in the present invention.Wherein adopt helicitic texture butt joint or seccotine butt joint to have better manufacturability.
For two application of sample pipes of in operation convenient difference fast, two application of sample pipes described in the present invention are designed to that one is long and the other is short.
Can also the head cross sectional shape of said two application of sample pipes be designed to two kinds of different shapes.
Consider that from the manufacturing process angle one of the head cross sectional shape of two application of sample pipes described in the present invention is circular, another root is a square; Or one be oval, and another root be square; Or one be circular, and another root is a rectangle.
The present invention is simple in structure, low cost of manufacture, and disposable use, safe and reliable, use the present invention's cross matching experiment of transfusing blood, Fang Bian ﹑ is quick, is difficult for makeing mistakes; And because the present invention is designed with transparent plastic book membrane vesicle, can directly use microscope to observe each cross reaction, have or not bad reactions such as tiny aggegation, save every round sample time or infected possibility that the glass test tube changes slide.
(4) description of drawings:
Fig. 1 is a structural representation of the present invention;
Fig. 2 adopts the present invention to carry out the constitutional diagram that is used in combination of a fork one experiment;
Fig. 3 adopts the present invention to carry out the constitutional diagram that is used in combination of y-bend one experiment.
Among the figure: 1-application of sample pipe, 2-application of sample pipe, 3-book membrane vesicle, 4-small powder pipe, 5-small test tube.
(5) embodiment:
Referring to Fig. 1, the present invention adopts the small test tube 5 of transparent plastic moulding, and is suitable for reading to being connected to two application of sample pipes 1 and 2 at small test tube 5, and wherein the head cross section of application of sample pipe 1 is a square, and the head cross section of application of sample pipe 2 is circular, to show difference; Two application of sample pipes 1 and 2 head can also be processed two kinds of mutually different other cross sectional shapes, like circle and rectangle, and rectangle and square, oval and square, various cooperations such as sexangle and rectangle.Can also two application of sample pipes be processed that one is long and the other is short to show difference.Certain two application of sample pipes process that the cross section is identical, and the length unanimity also is feasible, suitably carefully get final product during operation, or on the application of sample pipe, to make not isolabeling also are methods preferably.The top of small test tube 5 is also designed and is formed a small powder pipe 4 towards outside among the present invention, and small powder pipe 4 outer ends are bonded with a little plastic, transparent book membrane vesicle 3, promptly constitute the present invention.
Two application of sample pipes 1 among the present invention and 2 can with small test tube 5 one-shot formings, adopt the helicitic texture butt joint after can also distinguishing moulding, or seccotine butt joint one.
Operation instruction of the present invention is following:
1. a fork one experiment (when the receptor only needs blood donor's blood):
Get two of disposable blood transfusion cross matching experiment combiners, divide two groups of cross arrangements with four application of sample pipes of two combiners by Fig. 2, and combine in twos with rubber band, wherein two rounded nose application of sample pipes are for adding blood cell suspension pipe, and two square spigot application of sample pipes are for healing pigging; Wherein a small test tube is for being responsible for, and another small test tube is a time pipe; In the person in charge, add receptor's serum and blood donor's blood cell suspension then, in inferior pipe, add receptor's blood cell suspension and blood donor's serum.Carry out following operation again:
(1), moulds the interior thing mixing that intersects of pipe to above two and put into 25 ℃ of incubators reactions 5~10 minutes;
(2), took out low-speed centrifugal 2 minutes, take out and observe supernatant respectively, have or not haemolysis, agglutination phenomenon;
(3), if no haemolysis, no agglutination phenomenon then will be moulded the tube reaction thing and shaken up and touch in the reaction capsule.With microscopic examination, have or not tiny agglutination phenomenon;
(4), abovely all do not have haemolysis, no agglutination phenomenon, conclusion " meets " report; Otherwise go out " not meeting " report.
2. y-bend one experiment (when the receptor needs two blood donor's blood):
Get 9 of disposable blood transfusion cross matching experiment combiners, divide six groups of cross arrangements with 18 application of sample pipes of 9 combiners by Fig. 3, and use the rubber band packet assembling.And do A, B, C and A', B', C' numbering.Pour into receptor's blood cell suspension to A number three application of sample pipes then, pour into first blood donor's blood cell suspension, pour into second blood donor's blood cell suspension to C number three application of sample pipes to B number three application of sample pipes; Pour into receptor's blood to A' number three application of sample pipes again, pour into first blood donor's serum, pour into second blood donor's serum to C' number three application of sample pipe to B' number three application of sample pipe.Subsequent operation and provide the report same fork one experiment.
  

Claims (5)

1. disposable blood transfusion cross matching experiment combiner has the transparent plastic small test tube, it is characterized in that: suitable for reading at small test tube simultaneously to being connected to two application of sample pipes, and through small powder pipe fork-join one transparent plastic film capsule is arranged on the top of small test tube.
2. based on the described disposable blood transfusion cross matching experiment combiner of claim 1, it is characterized in that: said two application of sample pipes are that shaping one or employing helicitic texture dock or adopt the seccotine butt joint with small test tube.
3. disposable blood transfusion cross matching experiment combiner according to claim 1 and 2 is characterized in that: said two application of sample pipes are designed to that one is long and the other is short.
4. disposable blood transfusion cross matching experiment combiner according to claim 1 and 2, it is characterized in that: the cross sectional shape of said two application of sample tube heads is two kinds of different shapes.
5. based on the described disposable blood transfusion cross matching experiment combiner of claim 4, it is characterized in that: one of the cross sectional shape of said two application of sample tube heads is circle, and another root is a square; Or one be oval, and another root be square; Or one be circular, and another root is a rectangle.
CN201110021793.1A 2011-01-19 2011-01-19 Disposable transfusion and cross matching experiment combiner Active CN102608336B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201110021793.1A CN102608336B (en) 2011-01-19 2011-01-19 Disposable transfusion and cross matching experiment combiner
PCT/CN2011/002082 WO2012097494A1 (en) 2011-01-19 2011-12-12 Blood matching unit and combiner for disposable blood transfusion and cross matching experiment
CN2011800434378A CN103299194A (en) 2011-01-19 2011-12-12 Blood matching unit and combiner for disposable blood transfusion and cross matching experiment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201110021793.1A CN102608336B (en) 2011-01-19 2011-01-19 Disposable transfusion and cross matching experiment combiner

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CN102608336A true CN102608336A (en) 2012-07-25
CN102608336B CN102608336B (en) 2014-12-24

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CN2011800434378A Pending CN103299194A (en) 2011-01-19 2011-12-12 Blood matching unit and combiner for disposable blood transfusion and cross matching experiment

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104614538A (en) * 2015-02-13 2015-05-13 刘大基 Multifunctional disposable transfusion and cross blood-matching test combiner
CN109283037A (en) * 2018-09-03 2019-01-29 万峰春 A kind of crossmatch verifying attachment

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108593942B (en) * 2018-04-17 2020-09-08 杭州电子科技大学 Cross blood matching method

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CN201053967Y (en) * 2007-06-14 2008-04-30 四川省迈克科技有限责任公司 Quick detection reagent kit for blood type and transfusion matching type
CN201917576U (en) * 2011-01-19 2011-08-03 刘大基 Disposable blood transfusion and cross matching experiment combiner

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Publication number Priority date Publication date Assignee Title
CN2213337Y (en) * 1994-09-07 1995-11-22 卢道旭 Disposable micro-ABO blood grouping cup
EP0779103B1 (en) * 1995-12-13 2002-04-24 Pharmabio S.à.r.l. Device for visually assaying a liquid by mixing with a liquid reagent
CN1487298A (en) * 1996-02-02 2004-04-07 �ٴ����� Agglutination reaction and separating container
US5869347A (en) * 1996-03-18 1999-02-09 Stiftung Fur Diagnostische Forschung Praz-Rond Particle immunoassay using a compact matrix
CN2274957Y (en) * 1997-01-31 1998-02-25 张国典 Autoblood recovery device
CN2482084Y (en) * 2001-04-21 2002-03-13 李明雷 Special test tube stand for examination of cross blood match for blood transfusion
CN1438486A (en) * 2002-12-31 2003-08-27 江西中德生物工程有限公司 Method for detecting ABO blood type using immuno-chromatography, its prepared indicator paper and use
CN1849514A (en) * 2003-07-08 2006-10-18 因韦尔尼斯医药瑞士股份有限公司 Particle agglutination detection method and device
CN1894584A (en) * 2003-07-09 2007-01-10 麦迪奥诊断产品有限公司 Device and method for simultaneously carrying out blood group determination, serum cross-check and antibody detection test
WO2005052594A1 (en) * 2003-11-29 2005-06-09 Digital Bio Technology Method of examining blood type and apparatus for examining blood type using the method.
JP2006133136A (en) * 2004-11-08 2006-05-25 Nipro Corp Blood type determination device and blood type determination method
CN2766779Y (en) * 2005-02-05 2006-03-29 李大鹏 Disposable multi-function blood sampling/transfusing apparatus
CN201053967Y (en) * 2007-06-14 2008-04-30 四川省迈克科技有限责任公司 Quick detection reagent kit for blood type and transfusion matching type
CN201917576U (en) * 2011-01-19 2011-08-03 刘大基 Disposable blood transfusion and cross matching experiment combiner

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104614538A (en) * 2015-02-13 2015-05-13 刘大基 Multifunctional disposable transfusion and cross blood-matching test combiner
CN109283037A (en) * 2018-09-03 2019-01-29 万峰春 A kind of crossmatch verifying attachment

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CN103299194A (en) 2013-09-11
WO2012097494A1 (en) 2012-07-26
CN102608336B (en) 2014-12-24

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