CN102551901A - Oral implantation method for improving jaw bearing mode and screw implant - Google Patents

Oral implantation method for improving jaw bearing mode and screw implant Download PDF

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CN102551901A
CN102551901A CN2011104115477A CN201110411547A CN102551901A CN 102551901 A CN102551901 A CN 102551901A CN 2011104115477 A CN2011104115477 A CN 2011104115477A CN 201110411547 A CN201110411547 A CN 201110411547A CN 102551901 A CN102551901 A CN 102551901A
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swivel nut
matrix
thread
bone
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CN102551901B (en
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樊瑜波
韩景芸
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Beihang University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0018Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
    • A61C8/0022Self-screwing

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Abstract

The invention discloses an oral implantation method for improving a jaw bearing mode and a screw implant. A spring-shaped screw with internal and external threads is made of pure titanium or titanium alloy with a diamond section; and the screw consists of a cortical bone section with fine threads and a cancellous bone section with coarse threads, and is arranged in a jaw spare hole in a compressed state, so that prestretching stress is formed in a bone tissue. A matrix is a cylindrical external thread main body, and is separated into a gum penetration section, a fine thread section, a coarse thread section and a guide section from top to bottom, and the center of the matrix is a composite cavity; external threads of the fine thread section and the coarse thread section are matched with internal threads of the cortical bone section and the cancellous bone section to form threaded connection; and the guide section is a one-third segment, and the bottom of the guide section is provided with a crossed groove. By the invention, the conventional integrated implant is optimized into a composite implant that the screw and the matrix are matched, the invention has the advantages of reliable connection and low possibility of loosening, the stress level of the alveolar ridge crest can be reduced, chewing impact can be relieved, and jaw damage and absorption can be effectively prevented.

Description

A kind of tooth-planting method and swivel nut type implantation body that improves the jawbone bearing mode
Technical field
The present invention relates to a kind of tooth-planting method of improving the jawbone bearing mode, and a kind of swivel nut type mouth cavity planting body, the endosseous implant field belonged to.
Background technology
China is populous nation, but lacks about the understanding of oral health knowledge, and not strong to the consciousness of oral cavity health, China has become the district occurred frequently of oral disease at present.National for the third time oral health epidemiological survey result according to accomplishing in 2006 shows: in, old people's absence of tooth is serious, middle age is 2~6 of absence of tooth per capita, the old people is 11 of absence of tooth per capita, and 61.8% old people is an edentulous jaw.At present, there are three kinds at the common missing tooth restorative procedure of clinical oral: detachable dental prostheses, fixed denture and Dental Implant.Detachable dental prostheses utilizes maintenance mechanism attached on the adjacent tooth in agomphosis place, have freely pluck wear, characteristics convenient for cleaning; But maintenance property and aesthetic property are poor, foreign body sensation is chewed, had in influence, are prone to cause dysphonia.Fixed denture is abutment with the adjacent teeth, by bonding agent artificial tooth is fixed on it, and the patient need not get voluntarily and wear, and has characteristics such as volume is little, comfortable, attractive in appearance, no foreign body sensation; But repair process needs the reconditioning adjacent teeth, can sacrifice normal structure health, and the artificial tooth bottom is difficult for cleaning.
The sixties in 20th century; The breadboard orthopedics expert of Sweden Nobel
Figure BDA0000118746060000011
professor leader's research group has proposed bone and has integrated theoretical; Successfully researched and developed simultaneously the clinical modern tooth-planting system that is applied to; And accomplished in the world the first routine tooth-planting operation in nineteen sixty-five; So far after, this bio-imitability artificial tooth is developed rapidly and is used clinical.Developing rapidly of simultaneous clinical practice; The intension of modern tooth-planting greatly enriches and grows up; The science that has formed a whole set of rationale, histopathology, surgery, Implant Prosthesis about modern tooth-planting with put into practice system, become an Oral Science specialty with fastest developing speed in this century.Implantation body often is divided into four types with it clinically as the supportive device of artificial tooth: plant, wear the bone plantation in endosseous implant, subperiosteum plantation, the root pipe.At present, what application was the widest at most is endosteal implant, and Branemark, ITI, IMZ, BLB etc. are the famous brand name of domestic and international implantation body.Though the brand of implantation body is numerous at present; But its structure is similar basically with the clinical manipulation process: implantation body has one and is with externally threaded cylindric or cone shape matrix, and matrix is generally processed by metal or bioceramic, the hole that the clinician is similar to size of drill bit preparation and implantation body's profile in the jawbone zone of patient's missing tooth; Then implantation body is implanted in the hole; With the effect of simulation from the body root of the tooth, on matrix, place base station and artificial tooth at last, finally accomplish the reparation of oral cavity missing tooth.This artificial tooth made from planting patterns has the incomparable repairing effect of traditional artificial tooth, is described as the 3rd human secondary tooth.
Though tooth-planting has become a kind of reparation form that doctors and patients are easy to accept at present, and is promoted widely clinical, also has problems itself with regard to implantation body, influences clinical efficacy and success rate.As everyone knows, the oral cavity is a very complex environment, after wherein implantation body plants in jawbone, and the meeting masticatory force that bearing strength differs, frequency does not wait.Classical plantation is theoretical to be proposed; After implanting, implantation body needs experience one section non-loaded healing stage (3~6 months); Could device dummy, and the field of planting expert proposes the early stage load or even the notion of load at once in recent years, and in the clinical comparatively success rate of approval that obtains.But existing implantation body; Because the limitation of integral structure; When bearing load, can form the region of high stress in the zone near alveolar bone ridge top, have document to prove especially, the stress intensity of bone regeneration around implant bone can reduce along with the raising of bone degree of integration significantly.And planting the early stage of healing; The bone regeneration around implant bone is experiencing the bone process of reconstruction, and also generation or degree of integration are very not low for the integration between implantation body and the osseous tissue, and the intensity at interface is very poor; When therefore bearing function load in early days; Existing implantation body will form stress concentration in alveolar ridge crest, forms overload, causes bone resorption; Simultaneously owing to also do not form the integration of real meaning between implantation body and the bone, so implantation body is stable very poor, when bearing the masticatory force of intensity greatly, can cause the fine motion of implantation body, and the fine motion meeting of implantation body at the interface directly influences symphysis; In addition,, cause many complication, and can increase the difficulty that secondary is repaired greatly in case existing implantation body will cause serious injury to the surrounding bone tissue clinical going wrong.Based on above statement, can find out that not only there is the practical problem that influences aesthetics and functional rehabilitation in existing implantation body, and can directly cause the loosening of clinical implantation body and come off.
Summary of the invention
In order to overcome existing implantation body when bearing masticatory force; Cause the phenomenon of alveolar bone ridge top stress concentration; Simultaneously also in order to improve the replaceability after the stability of implantation body in agglutination is damaged with implantation body, this paper has invented and can effectively improve the tooth-planting method of jawbone internal stress of bone distribution and a kind of implantation body of swivel nut type after a kind of tooth-planting carries.The present invention has optimized the structure of implantation body and has formed; Different fully with the design concept of existing product; Can guarantee the primary stability of implantation body and good replaceability; Most importantly can obviously reduce the stress concentration phenomenon on bone regeneration around implant alveolar bone ridge top, make chewing load and can more evenly obtaining disperseing of bearing, thereby can effectively reduce stress to concentrate and the bone resorption that causes; The normal reconstruct and the integration of surrounding bone tissue be can effectively guarantee, plantation success rate at a specified future date and the purpose that improves the Implant Prosthesis aesthetics in the raising reached.
The method that the present invention solves existing issue in advance and adopted is: will have the structure of implantation body through the interior maintenance of himself external screw thread realization bone now, and become the double-piece structure of indirect retention, be i.e. swivel nut (1) and the combined interior retention system of bone of matrix (2).Adopt pure titanium of medical grade or titanium alloy to make the spiral type swivel nut (1) of spring-like, form external screw thread and female thread at outer surface and inner surface respectively.When tooth-planting, swivel nut (1) will be equipped with in the hole with the compressive state jawbone of packing into, thereby form pre-tensile stress in the osseous tissue around.Simultaneously, according to the difference of position in the bone, will make closely-pitched near the screw thread in Compact bone zone, and other parts are made coarse thread.In addition, matrix (2) is also processed by pure titanium of medical grade or titanium alloy, adopts column type external screw thread body design, and its external screw thread also is divided into closely-pitched section (40) and coarse thread section (50).When clinical use, matrix (2) is screwed in the mounted swivel nut (1), form firm being threaded with the screw-internal thread fit of swivel nut, thereby accomplish the interior maintenance of bone of implantation body.
The implantation body that is used for said method comprises 2 parts: swivel nut (1) and matrix (2), and its configuration design is following:
Said swivel nut (1) profile is the spirillum of spring-like, and its cross section is rhombus or type rhombus, is divided into cortical bone section (10) and spongy bone section (20) from top to bottom;
These two sections spirochetal outer surfaces of swivel nut and inner surface are shaped to external screw thread (101 respectively; 201) and female thread structure (102; 202); Wherein the screw thread of cortical bone section (10) adopts thinner tooth form, and the screw thread of spongy bone section (20) adopts thicker tooth form, and the tooth form of screw thread can be triangle thread shape, rectangular thread, trapezoidal thread or circular arc screw thread;
Said swivel nut (1) is the compression-type swivel nut; With being equipped with the hole and cooperating of jawbone the time; It will screw in compressive state, and the cortical bone district (3) that the external screw thread (101) and the jawbone of cortical bone section (10) is equipped with the hole matches, and spongy bone section (20) external screw thread (201) then matches with the spongy bone district (4) that jawbone is equipped with the hole; After the swivel nut maintenance, can in the osseous tissue around the swivel nut, form prestressing force;
Said matrix (2) is divided into from top to bottom and wears gum section (30), closely-pitched section (40), coarse thread section (50) and import canned paragraph (60); Described matrix center is a compound cavity (70), and this compound cavity (70) is used to place the base station that artificial tooth is installed;
Said main body of wearing gum section (30) is up big and down small round platform (301), and the top of round platform is a taper chamfering (302);
Said closely-pitched section (40) and coarse thread section (50) are column structure; The outer surface of cylinder is respectively equipped with external screw thread (401) and (501) of thin and thick thread; Female thread (201) and (202) of the tooth form of external screw thread (401) and (501) and swivel nut (1) are complementary; Both are when clinical use, and supporting use forms stable being threaded;
Said importing canned paragraph (60) is 1/3rd segment, and the outer surface of this segment is provided with cross recess (601);
Said compound cavity (70) is from top to bottom for having the conical bore (701) and the cylinder internal thread hole (702) of Morse's taper;
Described matrix (2) is designated as D with its externally threaded external diameter, and the height of its closely-pitched section (40) and coarse thread section (50) is designated as d respectively 1, d 2, the overall height of matrix in bone is designated as H, and H=d is then arranged 1+ d 2+ D/3.In order in clinical practice, to realize and the cooperating of the cortical bone of different-thickness, with matrix according to d 1The difference of height is divided into six series, the d of six types of being 1Highly be respectively 1mm, 1.5mm, 2mm, 2.5mm, 3mm and 3.5mm.Overall height H can be set to 8~22mm, and D can be set to 3~5mm;
Said matrix (2) will with the supporting use of swivel nut (1), therefore with swivel nut (1) according to cortical bone section height d 3Difference, also be divided into six series with matrix coupling, the d that each is serial 3With with a series of d 1Compare, highly differ 0.1~0.5mm; The height of matrix (1) coarse thread section (50) and swivel nut (2) spongy bone section (20) differs 0.5~5mm simultaneously;
Total thread turns of described matrix (2) and swivel nut (1) equates that the external screw thread of matrix (2) closely-pitched section (30) is identical with the tooth form of the female thread of swivel nut (1) cortical bone section (10); The external screw thread of matrix (2) coarse thread section (50) is identical with the tooth form of the female thread of swivel nut (1) spongy bone section (20);
Improving the tooth-planting method of jawbone bearing mode and the advantage of swivel nut type implantation body behind a kind of tooth-planting of the present invention is:
[1] help the uniform distribution of masticatory force in alveolar bone: zoopery and clinical experiment all prove; Under the effect of masticatory force; Existing implantation body can cause the higher concentrated load of intensity to alveolar bone ridge top, and this load can further cause the absorption of alveolar bone, and in a single day alveolar bone is absorbed; The metal section and part that will expose implantation body has a strong impact on the aesthetic property that implantation body repairs.Implantation body of the present invention has increased screw bushing structure; And in bigger tiny being threaded of cortical bone district employing thread of density; Can effectively alleviate the stress level of the former buttons of alveolar bone ridge top district's screw thread; Make masticatory force along implantation body's axis more even distribution, thereby can effectively avoid or reduce jaw absorption.
[2] help improving the primary stability of implantation body: swivel nut shape such as spring; Behind the hole fully in screwing in alveolar bone, its outer surface leans on elastic force can fit tightly on the internal thread hole of bone wall, and the female thread that its inner surface then forms with matrix matches is connected; This structure can obviously improve the primary stability of swivel nut relative bone tissue on the one hand; On the other hand, matrix cooperates with swivel nut because be after screwing in; The bonding strength and the wearability of matrix can be obviously improved, the loose or dislocation of matrix can be effectively prevented.
[3] secondary that helps implantation body is replaced: existing implantation body is in case damage; In the taking-up process, need uproop; Can cause severe trauma to the surrounding bone tissue, and between matrix and osseous tissue, increase screw bushing structure among the present invention, make when matrix goes wrong in clinical practice; Only need being threaded between loosening matrix and the swivel nut; It is just passable only to take out matrix, and is also keeping primary matching relationship between osseous tissue and the swivel nut, thereby can avoid because the damage of matrix and damage that osseous tissue is caused.
[4] help in alveolar bone, to be formed with the pre-stress environment that is beneficial to the bone reconstruction: the swivel nut that designs among the present invention is different from steel-wire screw-socket commonly used in the frame for movement; Latter's use is similar with extension spring; It is screwed in the counterpart with extended state; Swivel nut use among the present invention is then similar with stage clip, and it is to be screwed in the jawbone with compressive state, so swivel nut can produce initial tension to the jawbone that matches with it.And experiment is verified, and the tension of certain intensity helps the reconstruction of osseous tissue and prevention of bone to absorb.In addition, masticatory force can form compressive stress in osseous tissue, and this compressive stress of alleviation that the tension that swivel nut forms in bone among the present invention just just can be to a certain degree, thereby can further reduce the harmful effect of masticatory force to bone.
Description of drawings
Fig. 1 is the assembling sketch map of implantation body of the present invention and alveolar bone.
Fig. 2 is the positive visual angle outline drawing of swivel nut of the present invention.
Fig. 2 A is the side-looking angle outline drawing of swivel nut of the present invention.
Fig. 2 B is the opposite side visual angle outline drawing of swivel nut of the present invention.
Fig. 3 is the side-looking angle outline drawing of matrix of the present invention.
Fig. 3 A is the opposite side visual angle outline drawing of matrix of the present invention.
Fig. 3 B is the positive visual angle outline drawing of matrix of the present invention.
Fig. 3 C be matrix of the present invention partly cut open outline drawing.
The specific embodiment:
Below in conjunction with accompanying drawing and implementation process the present invention is done further detailed description.
Referring to shown in Figure 1; The present invention has showed a kind of mouth cavity planting body that improves tooth-planting method and a kind of swivel nut type of jawbone bearing mode; This method and implantation body are transformed into the pattern by the swivel nut indirect retention with the mode of existing dependence cylinder or circular cone external screw thread maintenance in jawbone.Mouth cavity planting body of the present invention comprises swivel nut (1) and matrix (2) two parts, and wherein the swivel nut external screw thread is screwed into osseous tissue, plays the effect of maintenance in the bone, and the female thread of swivel nut (1) then cooperates with matrix (2), forms stable female thread and connects.
Shown in Fig. 2,2A, 2B, among the present invention, swivel nut (1) profile is the spirillum of spring-like, and its height is divided into cortical bone section (10) and spongy bone section (20) from top to bottom greater than the height H of part in the bone of matching used matrix with it.When doing implant surgery; Swivel nut (1) screws in being equipped with in the hole of jawbone with the state of pressurized; Wherein the external screw thread (101) of cortical bone section (10) contacts with the cortical bone district (3) of alveolar bone, and the external screw thread (201) of spongy bone section (20) then contacts with the spongy bone district (4) of alveolar bone.In order to make implantation body of the present invention be applicable to the plantation in clinical different-thickness cortical bone district, the present invention is designed to different height with the cortical bone section (10) and the closely-pitched section (30) of swivel nut (1) and matrix (2) respectively, forms 6 series simultaneously.Therefore in clinical use, be according to patient's sclerotin, especially the thickness of Compact bone is selected the swivel nut (1) and the matrix (2) that can better mate with it.
Shown in Fig. 3,3A, 3B, 3C, in the present invention, the outer surface of matrix (2) from top to bottom comprises to be worn gum section (30), closely-pitched section (40), coarse thread section (50) and imports canned paragraph (60).When doing implant surgery, wear gum section (30) and need be positioned at below the high point of gingiva, avoid and exceed the gingiva face, whole round platform (301) need be positioned at more than the jawbone, and by the soft tissue parcel, and that wears gum section (30) and be implant operation wears the gum part.The external screw thread (401) of matrix (2) closely-pitched section (40) and the external screw thread (501) of coarse thread section (50) form in the screw thread with the female thread (202) of the female thread (102) of swivel nut (1) cortical bone section (10) and spongy bone section (20) respectively and are connected, thereby make matrix pass through swivel nut (1) indirect retention in jawbone.The profile that matrix (2) imports canned paragraph (60) is 1/3rd segments; The end face of this segment is provided with cross recess (601); This cross recess (601) helps growing into of newborn spongy bone, can further improve the stability of implantation body bottom, helps to alleviate the impact of vertical masticatory force.
Shown in Fig. 3 C, in the present invention, compound cavity (70) is conical bore (701) and the cylinder internal thread hole (702) with Morse's taper under last, is used for clinical plantation art gingival former or formal base station are installed.
Referring to shown in Figure 1; Of the present invention kind of method for planting compared with product with prior art with implantation body, can significantly lower the stress concentration on alveolar bone ridge top, can alleviate the process of chewing and carry the impact to osseous tissue at home and abroad; Help the uniform distribution of masticatory force in alveolar bone; In the time of can effectively avoiding simultaneously plantation to go wrong,, be convenient to the secondary reparation because of implantation body takes out the wound that osseous tissue is caused.Implantation body of the present invention is described below in the detailed process of clinical use:
1) early-stage preparations:, the art district is carried out otch, turns over preliminary preparations such as lobe and alveolar ridge finishing like conventional planting patterns; Also can adopt the plantation form of not turning over lobe only to the sterilization of art district.
2) bore locating hole: through surgical guide, use the drill bit of diameter 1.6~2.0mm in jawbone, to prepare, and detect the direction and the degree of depth of hole, as have error, need in time adjust through test rod.
3) spongy bone district implantation hole molding: the diameter that the molding of spongy bone district is bored and the diameter of implantation body's corresponding position differ 0.7-1.1mm; Difference according to patient's sclerotin; Adopt the drill bit of different size, like sclerotin patient preferably, can adopt diameter less relatively carry out molding.After the molding, as stated, utilize test rod to detect and adjust.
4) cortical bone implantation hole molding: utilize the molding of cortical bone district to be drilled on the basis that is equipped with the hole early stage,,, accurately control the degree of depth of hole molding through the stop device of surgical guide with the plantation mobile phone further at cortical bone district molding internal thread hole
5) implant swivel nut: utilize the swivel nut special spanner that swivel nut is screwed in, the external screw thread (101) of the swivel nut cortical bone section (10) of screw-in will be complementary with the cortical bone screwed hole of jawbone.After swivel nut was packed into, it should be in the minute-pressure state that contracts.
6) matrix is installed: utilize mobile phone to screw in matrix (2), use torque spanner then,, accomplish being threaded of matrix (2) and swivel nut (1) through the size of accurate control maintenance moment.
7) plantation post processing:,, and sew up soft tissue for gingival former or formal base station are laid by implantation body like routine plantation post surgery treatment method.

Claims (7)

1. tooth-planting method of improving the jawbone bearing mode; Being included in being equipped with of jawbone installs swivel nut (1) and the matrix (2) with external screw thread and female thread successively in the hole; It is characterized in that: adopt pure titanium of medical grade or titanium alloy to make the spiral type swivel nut (1) of spring-like, and form external screw thread and female thread at outer surface and inner surface respectively, swivel nut is screwed in jawbone be equipped with in the hole; Swivel nut is fixed in the jawbone through its external screw thread; Its female thread then then forms new internal thread hole in bone, then matrix is screwed in, and the external screw thread of matrix forms stable being threaded with the female thread of swivel nut.
2. the tooth-planting method of improving the jawbone bearing mode according to claim 1; It is characterized in that: the height of swivel nut (1) is greater than the height of matrix (2) part in bone; Swivel nut is the compression-type swivel nut; When jawbone is equipped with the hole and cooperates, it will be packed into the state that minute-pressure is contracted, thereby forms pre-tensile stress in the osseous tissue around.
3. swivel nut type implantation body; Comprise swivel nut (1) and matrix (2) two parts; It is characterized in that: swivel nut (1) profile is the spirillum of spring-like; Its cross section is rhombus or type rhombus, and its outer surface and inner surface are respectively external screw thread and female thread structure, are divided into cortical bone section (10) and spongy bone section (20) from top to bottom; Matrix is divided into from top to bottom to be worn gum section (30), closely-pitched section (40), coarse thread section (50) and imports canned paragraph (60); Described matrix center is a compound cavity (70).
The cortical bone section (10) of said swivel nut (1) adopts thin thread, and the screw thread of spongy bone section (20) adopts thicker tooth form, and the tooth form of screw thread can be triangle thread shape, rectangular thread, trapezoidal thread or circular arc screw thread.
The main body of said matrix (2) is up big and down small round platform (301), and the top of round platform is a taper chamfering (302);
The closely-pitched section (40) of said matrix (2) is cylinder external thread structure (401), and the female thread (102) of its external screw thread and swivel nut (1) cortical bone section (10) is used, and both thread turns are identical.
The coarse thread section (50) of said matrix (2) is cylinder external thread structure (501), and the female thread (202) of its external screw thread and swivel nut (1) spongy bone section (20) is used, and both thread turns are identical.
The importing canned paragraph (60) of said matrix (2) is 1/3rd segment, and the outer surface of this segment is provided with cross recess (601).
Said compound cavity (70) is from top to bottom for having the conical bore (701) and the cylinder internal thread hole (702) of Morse's taper.
4. according to the described swivel nut type of right 3 implantation body, it is characterized in that: the external diameter of the cylindrical thread of described matrix (2) is designated as D, and the height of its closely-pitched section (40) and coarse thread section (50) is designated as d respectively 1, d 2, the overall height of matrix (2) in bone is designated as H, and H=d is then arranged 1+ d 2+ D/3, with matrix (2) according to d 1The difference of height is divided into 6 series, the d of 6 types of being 1Highly be respectively 1mm, 1.5mm, 2mm, 2.5mm, 3mm and 3.5mm, overall height H can be set to 8~22mm, and D can be set to 3~5mm; Simultaneously with swivel nut (1) according to cortical bone section height d 3Difference, also be divided into 6 series that are complementary with matrix (1).
5. according to the described swivel nut type of right 3 implantation body, it is characterized in that: the height of swivel nut (1) cortical bone section (10) will be higher than the height of the closely-pitched section (40) of matrix (2), and both differ 0.1~0.5mm.
6. according to the described swivel nut type of right 3 implantation body, it is characterized in that: the height of swivel nut (1) spongy bone section (20) will be higher than the height of the coarse thread section (50) of matrix (2), and both differ 0.5~5mm.
7. according to the described swivel nut type of right 3 implantation body, it is characterized in that: swivel nut (1) and matrix (2) are made by pure titanium of medical grade or titanium alloy.
CN201110411547.7A 2011-12-12 2011-12-12 Oral implantation method for improving jaw bearing mode and screw implant Expired - Fee Related CN102551901B (en)

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CN105342712A (en) * 2015-12-03 2016-02-24 许丽艳 Oral implant device
CN106618767A (en) * 2016-12-29 2017-05-10 北京爱康宜诚医疗器材有限公司 Implant
CN113766894A (en) * 2019-04-30 2021-12-07 米尼翁大学 Dental implant, method of obtaining and use thereof

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