CN102526897B - Positioning method and system for high-intensity accumulated ultrasonic treatment of myoma - Google Patents
Positioning method and system for high-intensity accumulated ultrasonic treatment of myoma Download PDFInfo
- Publication number
- CN102526897B CN102526897B CN201110427232.1A CN201110427232A CN102526897B CN 102526897 B CN102526897 B CN 102526897B CN 201110427232 A CN201110427232 A CN 201110427232A CN 102526897 B CN102526897 B CN 102526897B
- Authority
- CN
- China
- Prior art keywords
- treatment
- module
- focal regions
- ultrasound wave
- muscular tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010061692 Benign muscle neoplasm Diseases 0.000 title claims abstract description 16
- 201000004458 Myoma Diseases 0.000 title claims abstract description 16
- 238000009210 therapy by ultrasound Methods 0.000 title claims abstract description 15
- 238000000034 method Methods 0.000 title abstract description 20
- 208000029312 Muscular tumor Diseases 0.000 claims description 60
- 238000002604 ultrasonography Methods 0.000 claims description 32
- 230000033001 locomotion Effects 0.000 claims description 16
- 238000002560 therapeutic procedure Methods 0.000 claims description 15
- 230000008859 change Effects 0.000 claims description 8
- 230000007246 mechanism Effects 0.000 claims description 7
- 238000012544 monitoring process Methods 0.000 claims description 4
- 238000005516 engineering process Methods 0.000 abstract description 4
- 230000008569 process Effects 0.000 description 8
- 230000004807 localization Effects 0.000 description 7
- 238000000354 decomposition reaction Methods 0.000 description 4
- 230000029058 respiratory gaseous exchange Effects 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 206010046798 Uterine leiomyoma Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000008901 benefit Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 201000010260 leiomyoma Diseases 0.000 description 1
- 201000007954 uterine fibroid Diseases 0.000 description 1
Abstract
The invention discloses a positioning method and system for high-intensity accumulated ultrasonic treatment of myoma. The method comprises the following steps of: acquiring an ultrasonic picture of myoma; receiving a coordinate value selected by a user on an ultrasonic picture; and performing a treatment region according to the coordinate value. According to the positioning method and system for high-intensity accumulated ultrasonic treatment of myoma provided by the invention, the accuracy of myoma positioning in a high-intensity accumulated ultrasonic treatment technology is increased.
Description
Technical field
The present invention relates to medical instruments field, refer more particularly to a kind of localization method for high-intensity accumulated ultrasonic treatment of myoma and system.
Background technology
High-strength focusing ultrasonic therapy technology is the very fast emerging medical skill of development in recent years, clinical practice in hysteromyoma is also very extensive, but in treatment, conformal crisperding becomes one of bottleneck of restriction raising Treatment of Uterine Leiomyoma with High Intensity Focused Ultrasond curative effect.
From current disclosed technical scheme, existing crisperding mode is mainly approximate crisperding: when delineating area for treatment, not the true form according to muscular tumor, but sketch out an ellipse according to the radial dimension of muscular tumor, replace actual muscular tumor shape with ellipse.The method is subdivided into again two kinds, and the first delineates two ellipses in 90 ° mutually, and according to these a two oval formation ellipsoid; The second is realized in vertical direction by ellipsoid being layering.No matter which kind of mode, not identical when the area for treatment of delineating and treatment, usually can contain the normal structure of part, even relate to important organ or nervus vasculairs, easily cause treatment accident.
Summary of the invention
Main purpose of the present invention, for providing a kind of localization method for high-intensity accumulated ultrasonic treatment of myoma and system, improves the accuracy of muscular tumor location in high-strength focusing ultrasonic therapy technology.
A kind of localization method for high-intensity accumulated ultrasonic treatment of myoma of the present invention, comprises step:
Gather the ultrasound wave picture of muscular tumor;
Receive the coordinate figure of user on described ultrasound wave picture;
Area for treatment is formed according to described coordinate figure.
Preferably, formed after area for treatment according to coordinate figure execution is described, also comprise:
Decompose described area for treatment by the size of ultrasonic focal regions, form one or more treatment focal regions;
Controlled motion mechanism carries out lattice scanning to described treatment focal regions;
Focal regions is treated the need of carrying out ultrasonic therapy according to the position information confirming of lattice scanning.
Preferably, in the described focal regions for the treatment of according to the position information confirming of lattice scanning of execution the need of after carrying out ultrasonic therapy, also comprise:
When confirming that a certain treatment focal regions needs to carry out ultrasonic therapy, ultrasound wave being launched to this treatment focal regions, gathers the ultrasound wave picture of this treatment focal regions simultaneously.
Preferably, the coordinate figure that described reception user selects on ultrasound wave picture comprises:
Select to increase, delete or change described coordinate figure according to user.
Preferably, while the ultrasound wave picture performing described collection muscular tumor, also comprise:
Show the dynamic 3 D figure of described area for treatment.
The present invention also proposes a kind of navigation system for high-intensity accumulated ultrasonic treatment of myoma, comprising:
Acquisition module, for gathering the ultrasound wave picture of muscular tumor;
Receiver module, for receiving the coordinate figure that user selects on described ultrasound wave picture;
Form module, for forming area for treatment according to described coordinate figure.
Preferably, described system also comprises:
Decomposing module, for decomposing described area for treatment by the size of ultrasonic focal regions, forms one or more treatment focal regions;
Control module, carries out lattice scanning for controlled motion mechanism to described treatment focal regions;
Confirm module, for treating focal regions the need of carrying out ultrasonic therapy according to the position information confirming of lattice scanning.
Described system also comprises:
Treatment monitoring module, for when confirming that a certain treatment focal regions needs to carry out ultrasonic therapy, launching ultrasound wave to this treatment focal regions, gathering the ultrasound wave picture of this treatment focal regions simultaneously.
Receiver module described in described system specifically for:
Select to increase, delete or change described coordinate figure according to user.
Described system also comprises:
Three dimensional display module, for while the ultrasound wave picture gathering muscular tumor, shows the dynamic 3 D figure of described area for treatment.
A kind of localization method for high-intensity accumulated ultrasonic treatment of myoma provided by the invention and system, needing the muscular tumor for the treatment of to carry out point-like crisperding, improve the Position location accuracy of muscular tumor area for treatment.In crisperding process, can also edit the positional information of each point, improve positional accuracy further.The present invention also achieves simultaneously and monitors in real time muscular tumor over the course for the treatment of, guarantees the concordance in area for treatment and muscular tumor region, guarantees that the position of position and the setting for the treatment of fits like a glove simultaneously.
Accompanying drawing explanation
Fig. 1 is the schematic flow sheet of the present invention for localization method one embodiment of high-intensity accumulated ultrasonic treatment of myoma;
The structural representation of Fig. 2 to be the present invention for the positioning systems of high-intensity accumulated ultrasonic treatment of myoma unify embodiment.
The realization of the object of the invention, functional characteristics and advantage will in conjunction with the embodiments, are described further with reference to accompanying drawing.
Detailed description of the invention
Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
With reference to Fig. 1, propose localization method one embodiment that the present invention is used for high-intensity accumulated ultrasonic treatment of myoma, comprise step:
The ultrasound wave picture of step S101, collection muscular tumor;
By ultrasound wave, image acquisition is carried out to muscular tumor before treatment, to determine suitable tangent plane direction, especially for multiple muscular tumor, include all muscular tumors in area for treatment as far as possible, once complete the treatment of polymyarian tumor.
The coordinate figure that step S102, reception user select on described ultrasound wave picture;
After ultrasonic acquisition piece image, receive operator by mouse along muscular tumor edge counterclockwise or click a series of coordinate points formed clockwise.
Step S103, form area for treatment according to described coordinate figure;
The coordinate points received in step S102 is connected by straight line, formed area for treatment, coordinate points is more, the area for treatment ticked and muscular tumor shape more close.
In order to accurately position area for treatment further, present embodiments provide the function of an editor, when muscular tumor is near important organ or nerve, in order to not injure normal structure, need to reduce crisperding scope, now only the coordinate points being not suitable for treating need to be changed into from needs therapeutic state by editting function does not need therapeutic state, thus alleviate the difficulty of crisperding, only according to muscular tumor shape crisperding, need need not consider the situation of surrounding when crisperding, accomplish complete conformal crisperding.For the situation of multiple muscular tumor, also without the need to carrying out repeatedly crisperding.
Step S104, decompose described area for treatment by the size of ultrasonic focal regions, form one or more treatment focal regions;
Fill the area for treatment chosen out, namely by large young pathbreaker's area for treatment uniform decomposition of ultrasonic focal regions, form the area for treatment that one or more is little, be difference area for treatment, one or more the little area for treatment after decomposition is referred to as to treat focal regions by the present embodiment.
Step S105, controlled motion mechanism carry out lattice scanning to described treatment focal regions;
After Plugging region, points all on ultrasonography is divided into two classes: area for treatment and non-treatment region.Information according to each coordinate points comprises positional information, and controlled motion mechanism carries out lattice scanning, and enters step S106.
Step S106, according to the position information confirming of lattice scanning, treat focal regions the need of carrying out ultrasonic therapy.
Judge that each treatment focal regions is the need for the treatment of according to the positional information of motion feedback in step S105, if need treatment, then control ultrasound emission systems emitting ultrasounds energy and treat.
Step S107, when confirm a certain treatment focal regions need to carry out ultrasonic therapy time, to this treatment focal regions launch ultrasound wave, gather the ultrasound wave picture of this treatment focal regions simultaneously.
Cannot monitor when treating in prior art for overcoming simultaneously, and cause treating produce deviation problem (muscular tumor pelvic cavity when treating be squeezed after with normality under there are differences in position, angle even shape etc., shear-face angle during treatment is also difficult to ensure that the shear-face angle with when checking is consistent.In addition, breathing and body movement also can cause muscular tumor to be among a change dynamically), the present embodiment, while carrying out ultrasonic therapy, also can be monitored by ultrasonic acquisition muscular tumor image simultaneously in real time.So can while treatment, the situation of muscular tumor position is observed on limit, guarantees the concordance in area for treatment and actual muscular tumor region.
Further, in order to be well understood to muscular tumor form, the present embodiment provides real-time three-dimensional Presentation Function, the image of ultrasonic acquisition is shown by 3-D view, therefore, when crisperding or when treatment monitors, the dynamic 3 D figure of muscular tumor is formed according to the information of crisperding, distinguish by different colors simultaneously and treated part and do not treated part, operator can be seen intuitively, and process is carried out in treatment, and according to treatment situation to not treating part unrestricted choice by carrying out or adjust treatment plan in the original plan.Simultaneously, muscular tumor graphics before the dynamic 3 D figure of muscular tumor and treatment can be contrasted, if there is huge shape difference or position skew, illustrate because the action of patient, breathing or body movement cause the motion change of muscular tumor, operator is reminded to keep a close eye on the process for the treatment of, supspend treatment if desired, carry out successive treatment again after reorientating, the treatment that reduces of maximum possible occurs unexpectedly.
The present embodiment carries out point-like crisperding in the muscular tumor of needs treatment, improves the Position location accuracy of muscular tumor area for treatment.In crisperding process, can also edit the positional information of each point, improve positional accuracy further.The present invention also achieves simultaneously and monitors in real time muscular tumor over the course for the treatment of, guarantees the concordance in area for treatment and muscular tumor region, guarantees that the position of position and the setting for the treatment of fits like a glove simultaneously.
With reference to Fig. 2, propose a kind of positioning systems for high-intensity accumulated ultrasonic treatment of myoma of the present invention and unify embodiment, comprising:
Acquisition module 10, for gathering the ultrasound wave picture of muscular tumor;
Receiver module 20, for receiving the coordinate figure that user selects on described ultrasound wave picture;
Form module 30, for forming area for treatment according to described coordinate figure;
Decomposing module 40, for decomposing described area for treatment by the size of ultrasonic focal regions, forms one or more treatment focal regions;
Control module 50, carries out lattice scanning for controlled motion mechanism to described treatment focal regions;
Confirm module 60, for treating focal regions the need of carrying out ultrasonic therapy according to the position information confirming of lattice scanning;
Treatment monitoring module 70, for when confirming that a certain treatment focal regions needs to carry out ultrasonic therapy, launching ultrasound wave to this treatment focal regions, gathering the ultrasound wave picture of this treatment focal regions simultaneously;
Three dimensional display module 80, for being formed while area for treatment according to coordinate figure execution is described, shows the dynamic 3 D figure of described area for treatment.
The system of the present embodiment, acquisition module 10, receiver module 20 and formation module 30 can be realized by host computer (software for treatment), decomposing module 30, control module 50 and confirmation module 60 can be realized by slave computer (PLC software), data interaction is carried out by communication module between host computer and slave computer, native system also comprises the motion controlled by slave computer, and a ultrasonic transmitter.
Before treatment, acquisition module 10 carries out image acquisition by ultrasound wave to muscular tumor, to determine suitable tangent plane direction, especially for multiple muscular tumor, includes all muscular tumors in area for treatment as far as possible, once completes the treatment of polymyarian tumor.After acquisition module 10 gathers piece image, receiver module 20 receives operator by mouse along muscular tumor edge counterclockwise or click a series of coordinate points formed clockwise.An above-mentioned system coordinates point is connected by straight line by formation module 30, formed area for treatment, coordinate points is more, the area for treatment ticked and muscular tumor shape more close.
In order to accurately position area for treatment further, receiver module 20 also possesses the function of editor, when muscular tumor is near important organ or nerve, in order to not injure normal structure, need to reduce crisperding scope, now the coordinate points being not suitable for treating only need to change into from needs therapeutic state according to the selection of operator by receiver module 20 does not need therapeutic state, thus alleviate the difficulty of operator's crisperding, only need according to muscular tumor shape crisperding when crisperding, the situation of surrounding need not be considered, accomplish complete conformal crisperding.For the situation of multiple muscular tumor, also without the need to carrying out repeatedly crisperding.
Decomposing module 40 is filled the area for treatment chosen out, namely by large young pathbreaker's area for treatment uniform decomposition of ultrasonic focal regions, form the area for treatment that one or more is little, be difference area for treatment, one or more the little area for treatment after decomposition is referred to as to treat focal regions by the present embodiment.After Plugging region, points all on ultrasonography is divided into two classes: area for treatment and non-treatment region.Control module 50 comprises positional information according to the information of each coordinate points, controlled motion mechanism carries out lattice scanning, confirm according to the positional information that motion feeds back, module 60 judges that each treatment focal regions is the need for the treatment of, if need treatment, then control ultrasound emission systems emitting ultrasounds energy and treat.
Cannot monitor when treating in prior art for overcoming simultaneously, and cause treating produce deviation problem (muscular tumor pelvic cavity when treating be squeezed after with normality under there are differences in position, angle even shape etc., shear-face angle during treatment is also difficult to ensure that the shear-face angle with when checking is consistent.In addition, breathing and body movement also can cause muscular tumor to be among a change dynamically), the present embodiment is while carrying out ultrasonic therapy, and treatment monitoring module 70 also can be monitored by ultrasonic acquisition muscular tumor image simultaneously in real time.So can while treatment, the situation of muscular tumor position is observed on limit, guarantees the concordance in area for treatment and actual muscular tumor region.
Further, in order to be well understood to muscular tumor form, the three dimensional display module 80 of the present embodiment is when crisperding or when treatment monitors, the dynamic 3 D figure of muscular tumor is formed according to the information of crisperding, distinguish by different colors simultaneously and treated part and do not treated part, operator can be seen intuitively, and process is carried out in treatment, and according to treatment situation to not treating part unrestricted choice by carrying out or adjust treatment plan in the original plan.Simultaneously, muscular tumor graphics before the dynamic 3 D figure of muscular tumor and treatment can be contrasted, if there is huge shape difference or position skew, illustrate because the action of patient, breathing or body movement cause the motion change of muscular tumor, operator is reminded to keep a close eye on the process for the treatment of, supspend treatment if desired, carry out successive treatment again after reorientating, the treatment that reduces of maximum possible occurs unexpectedly.
The present embodiment carries out point-like crisperding in the muscular tumor of needs treatment, improves the Position location accuracy of muscular tumor area for treatment.In crisperding process, can also edit the positional information of each point, improve positional accuracy further.The present invention also achieves simultaneously and monitors in real time muscular tumor over the course for the treatment of, guarantees the concordance in area for treatment and muscular tumor region, guarantees that the position of position and the setting for the treatment of fits like a glove simultaneously.
The foregoing is only the preferred embodiments of the present invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.
Claims (4)
1. for a navigation system for high-intensity accumulated ultrasonic treatment of myoma, it is characterized in that, comprising:
Acquisition module, for gathering the ultrasound wave picture of muscular tumor;
Receiver module, for receiving the coordinate figure that user selects on described ultrasound wave picture;
Form module, for forming area for treatment according to described coordinate figure;
Also comprise:
Decomposing module, for decomposing described area for treatment by the size of ultrasonic focal regions, forms multiple treatment focal regions;
Control module, carries out lattice scanning for controlled motion mechanism to described treatment focal regions;
Confirm module, for treating focal regions the need of carrying out ultrasonic therapy according to the position information confirming of lattice scanning.
2. navigation system as claimed in claim 1, is characterized in that, also comprise:
Treatment monitoring module, for when confirming that a certain treatment focal regions needs to carry out ultrasonic therapy, launching ultrasound wave to this treatment focal regions, gathering the ultrasound wave picture of this treatment focal regions simultaneously.
3. the navigation system according to any one of claim 1 to 2, is characterized in that, described receiver module specifically for:
Select to increase, delete or change described coordinate figure according to user.
4. the navigation system according to any one of claim 1 to 2, is characterized in that, also comprises:
Three dimensional display module, for while the ultrasound wave picture gathering muscular tumor, shows the dynamic 3 D figure of described area for treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110427232.1A CN102526897B (en) | 2011-12-19 | 2011-12-19 | Positioning method and system for high-intensity accumulated ultrasonic treatment of myoma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110427232.1A CN102526897B (en) | 2011-12-19 | 2011-12-19 | Positioning method and system for high-intensity accumulated ultrasonic treatment of myoma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102526897A CN102526897A (en) | 2012-07-04 |
| CN102526897B true CN102526897B (en) | 2015-05-20 |
Family
ID=46335688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110427232.1A Active CN102526897B (en) | 2011-12-19 | 2011-12-19 | Positioning method and system for high-intensity accumulated ultrasonic treatment of myoma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102526897B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1413560A (en) * | 2002-12-23 | 2003-04-30 | 张祥康 | Automatic stereotaxic method and device of B-ultrasonic location extemal lithotriptor |
| CN1814321A (en) * | 2005-01-31 | 2006-08-09 | 重庆微海软件开发有限公司 | Control system for ultrasonic therapeutical equipment |
| CN1814323A (en) * | 2005-01-31 | 2006-08-09 | 重庆海扶(Hifu)技术有限公司 | Focusing ultrasonic therapeutical system |
| CN102166135A (en) * | 2010-02-25 | 2011-08-31 | 重庆融海超声医学工程研究中心有限公司 | High-intensity focused ultrasound treatment device |
| CN202654561U (en) * | 2011-12-19 | 2013-01-09 | 深圳市普罗惠仁医学科技有限公司 | Positioning device and positioning system used for high intensity aggregation supersonic wave treatment of myoma |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100490755C (en) * | 2004-06-11 | 2009-05-27 | 株式会社日立医药 | Ultrasonic curing device |
-
2011
- 2011-12-19 CN CN201110427232.1A patent/CN102526897B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1413560A (en) * | 2002-12-23 | 2003-04-30 | 张祥康 | Automatic stereotaxic method and device of B-ultrasonic location extemal lithotriptor |
| CN1814321A (en) * | 2005-01-31 | 2006-08-09 | 重庆微海软件开发有限公司 | Control system for ultrasonic therapeutical equipment |
| CN1814323A (en) * | 2005-01-31 | 2006-08-09 | 重庆海扶(Hifu)技术有限公司 | Focusing ultrasonic therapeutical system |
| CN102166135A (en) * | 2010-02-25 | 2011-08-31 | 重庆融海超声医学工程研究中心有限公司 | High-intensity focused ultrasound treatment device |
| CN202654561U (en) * | 2011-12-19 | 2013-01-09 | 深圳市普罗惠仁医学科技有限公司 | Positioning device and positioning system used for high intensity aggregation supersonic wave treatment of myoma |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102526897A (en) | 2012-07-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10588701B2 (en) | Systems, apparatus, methods and computer-readable storage media facilitating surgical procedures utilizing augmented reality | |
| CN106456135B (en) | Medical system | |
| CN107049497B (en) | Puncture navigation robot system | |
| US20200001114A1 (en) | Elasticity imaging-based methods for improved gating efficiency and dynamic margin adjustment in radiation therapy | |
| CN105534593B (en) | Intervention ablation simulation system and method | |
| US10314559B2 (en) | Medical device guidance | |
| US8819591B2 (en) | Treatment planning in a virtual environment | |
| CN103971574A (en) | Ultrasonic guidance tumor puncture training simulation system | |
| CA2867536A1 (en) | Method for creation of dynamic patient-specific surgical monitoring system | |
| CN108744313A (en) | Radiotherapy planning planing method, radiotherapy planning system and radiotherapy system | |
| CN204562381U (en) | Minimally invasive spine surgical navigation system | |
| CN102049106A (en) | Precise image positioning system and method of radiotherapy system of interfractionated radiotherapy | |
| CA2897439A1 (en) | Surgical training system | |
| CN101869501B (en) | Computer-aided needle scalpel positioning system | |
| CN106109016A (en) | Abdominal-cavity minimal-invasion surgery system and wherein play the determination method in pin moment | |
| US20170311118A1 (en) | Method and system for manufacturing compensator for total body irradiation using camera | |
| CN102526897B (en) | Positioning method and system for high-intensity accumulated ultrasonic treatment of myoma | |
| CN106446578B (en) | Image display method, device and system for implant surgery | |
| CN202654561U (en) | Positioning device and positioning system used for high intensity aggregation supersonic wave treatment of myoma | |
| CN101537230A (en) | Positioning method and device for radiotherapy | |
| JP7222562B1 (en) | HIFU treatment display device | |
| EP3297725A1 (en) | System for in-layer synchronization for fast spot rescanning | |
| CN218870415U (en) | Auxiliary device based on intracranial tumor puncture treatment | |
| CN109173084A (en) | A method of the tumour radiotherapy particle layout for laser aiming positioning | |
| CN113274654A (en) | Real-time monitoring system for ultrasound images of tumor and visceral organ positions for radiotherapy |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: Two road 518000 Guangdong city of Shenzhen province Nanshan District high tech Industrial Park, Xili Street No. 28 North Howell technology building floor area on the north side of D Patentee after: Shenzhen municipal medical Limited by Share Ltd Address before: 518000 Guangdong province Shenzhen city Nanshan District high tech Park North Song Ping Road No. 1 North Block Building 402 Lite Technology Patentee before: Puluohuiren Medicine Sci-Tech Co., Ltd., Shenzhen |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Positioning method and system for high-intensity accumulated ultrasonic treatment of myoma Effective date of registration: 20170804 Granted publication date: 20150520 Pledgee: Bank of Jiangsu Limited by Share Ltd Shenzhen branch Pledgor: Shenzhen municipal medical Limited by Share Ltd Registration number: 2017440020023 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20180830 Granted publication date: 20150520 Pledgee: Bank of Jiangsu Limited by Share Ltd Shenzhen branch Pledgor: Shenzhen municipal medical Limited by Share Ltd Registration number: 2017440020023 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Positioning method and system for high-intensity accumulated ultrasonic treatment of myoma Effective date of registration: 20180830 Granted publication date: 20150520 Pledgee: Bank of Jiangsu Limited by Share Ltd Shenzhen branch Pledgor: Shenzhen municipal medical Limited by Share Ltd Registration number: 2018440020052 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20200327 Granted publication date: 20150520 Pledgee: Bank of Jiangsu Limited by Share Ltd Shenzhen branch Pledgor: SHENZHEN PRO HITU MEDICAL Co.,Ltd. Registration number: 2018440020052 |