CN102512147A - Non-destructive detector for human arteriosclerosis - Google Patents
Non-destructive detector for human arteriosclerosis Download PDFInfo
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- CN102512147A CN102512147A CN2011104427661A CN201110442766A CN102512147A CN 102512147 A CN102512147 A CN 102512147A CN 2011104427661 A CN2011104427661 A CN 2011104427661A CN 201110442766 A CN201110442766 A CN 201110442766A CN 102512147 A CN102512147 A CN 102512147A
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Abstract
The invention relates to an instrument based on pulse transmission velocity and a pulse wave theory. The instrument comprises an arteriosclerosis detector host box, four sets of cuffs and rubber conduits, two sensors for detecting electrocardiographs and conducting wires as well as auxiliary wrist clips, a sensor for detecting heart sound signals, a microcomputer and a printer. The instrument is characterized in that: the electrocardiograph sensors and the heart sound sensor are connected with respective preprocessing modules respectively, then the preprocessing modules are connected with respective primary filtering modules, and finally the primary filtering modules are connected with a singlechip respectively; and the singlechip is also connected with a blood pressure signal amplification module and the microcomputer, and the blood pressure signal amplification module is connected with a blood pressure sensor. The hardware cost, the volume and the cost are reduced; and the instrument can be used for hospitals, communities and home environments. The instrument has a friendly software interface, is easy to operate, has multiple functions, and can store diagnostic reports under the condition that the printer is not arranged.
Description
Technical field
The present invention relates to electrical category; Particularly relate to a kind of based on pulse wave transmission speed and theoretical instrument or the system of pulse wave; It is through facing upward time and the analysis pulse waveform that flat human limb region of interest for sleeping in or any appointed part placement sensor measurement pulse wave transmit; Brachium conjunctivum ankle blood pressure index judges that the obstruction of artery situation also utilizes the measurement parameter of heart sound transducer to carry out the evaluation of human body artery spring level, meanwhile calculates the systolic pressure, diastolic pressure, mean pressure, pulse pressure, heart rate, waveform rise time, pulse wave volume record, ecg wave form, hear sounds waveform, systolic time interval of extremity etc.
Background technology
In recent years, along with the deep understanding of the mankind to the native blood vessel pathological changes, everybody recognize gradually the blood vessel wall pathological changes with and incidence and development due to the tube chamber pathological changes be only the immediate cause of multiple cardiovascular complications such as myocardial infarction, apoplexy.Have only through vascular lesion being carried out earlier detection, early discovery and intervention rationally and could fundamentally reduce it and disable and fatality rate.Cardiovascular disease is the pathological changes of involving whole body, and therefore, the whole vascular lesion of intervening is only the essential measure that reduces various cardiovascular events and improve patient's long-term prognosis.
The inspection of tradition arterial disease mainly is to adopt angiography and two kinds of methods of intravascular ultrasound.But these two kinds of methods all are the diagnosis to patient ill mid-term, late period; And be that traumatic inspection is arranged; Not only expense is high, and certain danger is arranged, and is not suitable for conventional examination; Therefore arteriosclerotic no wound earlier detection, early diagnosis, early stage control become the theme of contemporary medical science science and education and social development, also are the important topics that society proposes to the medical research personnel.
At present, cardiovascular diagnosis mainly relies on medical apparatus and instruments except clinical.Electrocardio and hear sounds are two kinds of different means that detect cardiovascular disease, and electrocardio is mainly used in analyzing and diagnosing and the curative effect of check cardiovascular drugs of the qualitative and quantitative of arrhythmia and myocardial ischemia.Phonocardiogram can effectively remedy the deficiency of cardiac auscultation, and cardiechema signals that cardiac auscultation can not be write down or the signal that is not easy to differentiate are noted with the form of data, figure, supplies the doctor to analyze use.Phonocardiogram combines electrocardiogram; Can effectively improve the discriminating and the diagnostic level of cardiovascular disease,, confirm therapeutic scheme for the analysis cardiovascular function; The mechanism of judging pathology and studying some disease all provides of great value scientific basis, and its application is increasingly extensive.
Blood pressure is the pressure that blood produces blood vessel wall when in blood vessel, flowing; As the physiological parameter that body weight for humans is wanted, blood pressure can reflect the function status of human heart and blood vessel, thereby becomes clinically and diagnose the illness; Observe therapeutic effect, carry out the more important evidence of back recovery judgement of disease.Along with people's to physiology signal characteristic understanding deepen continuously and a large amount of new technique is applied to biomedical engineering field, the scientist has proposed to utilize the method for pulse wave characteristic parameters continuous blood pressure measuring.Along with the intermittence of heart is shunk and diastole, blood stream pressure, the pulsation of VPV and blood flow and the distortion of blood vessel wall and the propagation of vibration in vascular system are referred to as the propagation in blood vessel of pulse wave or pulse wave.Information such as the form that pulse wave demonstrates, intensity, speed and the rhythm and pace of moving things reflect the flow characteristic of many physiology and pathology in the cardiovascular system of human body to a great extent.Pulse wave be a kind of be main physiological signal with the low-frequency component, can pass through the body surface tremulous pulse, locate to be detected like carotid artery, brachial artery and radial artery etc.
Pulse wave passing time PTT (Pulse Transmit Time) is meant that arterial pulse begins to pass to the time difference between a certain bifurcated artery blood vessel from heart contraction.This method is based on the principle that has certain functional relationship between transmission speed and each point pressure of pipe network internal pressure in the hydrodynamics; Systolic pressure and pulse passing time are set up one group of dependency number mathematic(al) function; Calculate systolic pressure in view of the above, and further estimate mean pressure and diastolic pressure.
Pulse wave velocity PWV (Pulse Wave Velocity) is obtained by the pulse wave propagate Time Calculation usually.Starting end (subclavian artery) and end (femoral artery) at tremulous pulse detect pulse; Can calculate two time differences between the signal; Known aortal length (with the distance estimations between suprasternal notch and the groin) can calculate aortic pulse wave speed.In general, hypertension, pulse increases along the spread speed of tremulous pulse.After detecting relevant pulse waveform, proofread and correct and to obtain absolute, successive blood pressure measurement.
Can press down blood vessel through placing arterial pulse the most obviously to locate the pressure detecting probe to the measurement of pulse wave, when artery surface is driven plain, circumferentially just being balanced of tube wall, the pressure that probe is remembered is exactly real intra-arterial pressure.Calculate systolic pressure and diastolic pressure through pulse wave translation time.The full-automatic survey meter of blood pressure of BP-50 type that Britain produces has just adopted this principle.Concrete grammar is: utilize the peak value of ecg-r wave to be starting point, the measure R ripple triggers the back pulse wave and is transmitted to the required time of finger tips, utilizes the systolic pressure set up and the regression equation of diastolic pressure again, and conduction time is scaled systolic pressure and diastolic pressure.
Theoretically, as long as the relation of pulse wave and cardiovascular blood flow rule well is familiar with and is solved, utilizing the pulse wave method to detect diagnosis human vas hemodynamic parameter is more appropriate best approach in other words conj.or perhaps.Arteriosclerosis is systemic disease; When the patient reduces because of angiostenosis or obstruction cause pulse wave velocity; Even tremulous pulse has suitable hardenability; The numerical value of PWV (pulse wave conduction speed) might still be acted normally, and has only the ABI of combination to carry out comprehensive assessment, just can accurately check out the patient of multiple vascular lesion.
ABI (ankle upper arm blood pressure ratio) is an index of judging that the artery of lower extremity that is caused by medicated porridge appearance arteriosclerosis is narrow, block.Through the blood pressure of synchro measure extremity, again by the ankle systolic pressure divided by value higher in the upper arm systolic pressure, obtain a result.According to ABI, can judge narrow, the congestion situations of artery of lower extremity.Diagnosis and postoperative observation for obstructive arteriosclerosis (ASO) are proper.In addition, through observing left and right sides upper arm blood pressure difference, can detect the abnormal conditions of artery of upper extremity such as large artery trunks inflammation and subclavian artery be narrow.
ABI is generally used as the index of diagnosis obstructive arteriosclerosis (ASO), and its criterion was formulated by AHA (american heart association) in 1993:
Tranquillization ABI value is in critical point and with the patient of intermittent claudication, the stress test of can taking exercises is so that further make a definite diagnosis.
Summary of the invention
When the objective of the invention is to the early stage arterial elasticity level of human body accurately and effectively and the misery that can avoid wound to bring, develop a kind of instrument of judging the obstruction of artery situation and utilizing the measurement parameter of heart sound transducer to carry out the evaluation of human body artery spring level based on pulse wave velocity brachium conjunctivum ankle blood pressure index to people.
The present invention realizes with following technical proposal:
Human body artery sclerosis nondestructive testing instrument; It comprises A/D modular converter, heart sound transducer, hear sounds pre-processing module, the elementary filtration module of hear sounds, pressure transducer, blood pressure signal amplification module under EGC sensor, electrocardio pre-processing module, the elementary filtration module of electrocardio, the Single-chip Controlling; It is characterized in that EGC sensor is connected pre-processing module separately respectively with heart sound transducer; Pre-processing module connects elementary filtration module separately more then; Connect single-chip microcomputer at last separately, said single-chip microcomputer also is connected with blood pressure signal amplification module and microcomputer, and the blood pressure signal amplification module connects pressure transducer.EGC sensor uses the wrist clamping to fix on wrist, is used to gather electrocardiosignal; The electrocardio pre-processing module is connected with EGC sensor, and the faint electrocardiosignal that this module will collect is amplified; The elementary filtration module of electrocardio links to each other with the electrocardio pre-processing module, to filter the noise of electrocardiosignal; A/D modular converter under the Single-chip Controlling becomes digital signal with the EGC analog conversion of signals; Heart sound transducer is placed on the outer apex position of thorax, is used to gather cardiechema signals; The hear sounds pre-processing module is connected with heart sound transducer, and the hear sounds pre-processing module is amplified the initial cardiechema signals that is collected; The elementary filtration module of hear sounds links to each other with the hear sounds pre-processing module, in order to filter the noise of cardiechema signals; Single-chip Controlling A/D modular converter becomes digital signal with the hear sounds analog signal conversion; Pressure transducer at first is fixed on extremity appointed part or any part with cuff, through rubber catheter air pressure pressure is sent to pick off, so that gather blood pressure signal, pulse transmission speed and pulse waveform; The blood pressure signal amplification module is connected with pressure transducer, and the blood pressure signal amplification module amplifies the blood pressure signal that is collected; Single-chip microcomputer is done data acquisition to blood pressure signal; Above-mentioned multichannel unlike signal is input to microcomputer simultaneously; The accompanying software of human body artery sclerosis nondestructive testing instrument will calculate time difference and ankle upper arm blood pressure ratio between electrocardiosignal and the blood pressure signal; In conjunction with cardiechema signals; Through analyzing pulse waveform, judge that accurately the arteriosclerosis degree calculates the systolic pressure of extremity, diastolic pressure, mean pressure, pulse pressure, heart rate, waveform rise time, pulse wave volume record, ecg wave form, hear sounds waveform, systolic time interval etc. simultaneously.Computer software can also carry out content and statistical procedures such as identification, collection height, body weight, age and gender data, storage personal illness history, test tracking except having above-mentioned functions.
The viewable portion of said human body artery sclerosis nondestructive testing instrument comprises a human body arteriosclerosis nondestructive testing instrument host box; Quadruplet cuff and rubber conduit; Two are detected cardiac electrical pick off and wrist folder, a pick off that detects cardiechema signals, a microcomputer and a printer; Characteristic is to use common non-special microcomputer and printer, and the collection of data signal, secondary filtering noise reduction and data computation all realize through the software that is installed on the microcomputer.
Can pressure transducer be placed on the location detection part of any known arteries length and know the blood vessel elasticity situation of whole body by inference.Different with other design philosophy or shaped article wherein is; The present invention considers the popularity of microcomputer and its versatility; The human body artery software that the most function of nondestructive testing instrument transfers to microcomputer that hardens is realized; Dwindled the volume of human body artery sclerosis nondestructive testing instrument, reduced cost, it can be used at hospital, community and domestic environment.Software interface is friendly, and simple to operate, diverse in function in the absence of printer, can be stored diagnosis report, connects printer and can print exquisite diagnostic result.
The present invention is based on as a kind of method that above-mentioned human body artery sclerosis nondestructive testing instrument realizes; The transmission of pulse has certain speed, and the elasticity of the size of speed and vascular system is inversely proportional to, and promptly the elasticity of vascular system is big more; The spread speed of pulse is low more, and vice versa.Human blood circulatory system's length is directly proportional with height, meets certain rules.Therefore gather pulse wave propagation speed in the human body appointed part; And brachium conjunctivum ankle blood pressure index is judged the obstruction of artery situation and is utilized the measurement parameter of heart sound transducer; Under human parameters data base's demarcation, can judge the human body artery spring level, effectively prevent early stage arteriosclerosis.The equipment cost that designs and produces according to this programme is low, easy maintenance, simple to operate, and the testing time is short, and the testee has no uncomfortable sensation.
Description of drawings
Fig. 1 human body artery sclerosis nondestructive testing instrument structural representation
1-1 human body artery sclerosis nondestructive testing instrument 1-2 EGC sensor 1-3 cuff 1-4 heart sound transducer 1-5 microcomputer 1-6 networking component 1-7 printer
The fixed position of Fig. 2 detected person cuff
A1, A2, A3, A4 are the fixed positions of cuff
Fig. 3 EGC sensor and wrist folder
3-1 pick off 3-2 lead
The specific embodiment
Further specify the working condition of human body artery sclerosis nondestructive testing instrument below in conjunction with legend.
Embodiment 1: the basic structure signal of human body artery sclerosis nondestructive testing instrument is as shown in Figure 1; Be connected through USB interface between human body artery sclerosis nondestructive testing instrument and the microcomputer; Then heart sound transducer is connected through the host box of special wire with human body artery sclerosis nondestructive testing instrument with EGC sensor; Microcomputer can select to connect the local printer and the network printer, and the data of surveying provide network retrieval.The detected person gets and faces upward flat prone position gesture, uncovers and is examined the position.Under the system boot state, heart sound transducer is placed on the outer apex position of thorax, and pushes down with light sandbag.
Embodiment 2: the operation to human body detects is as shown in Figure 2, and two cufves are fixed on upper arm place, the left and right sides, and two cufves are fixed on ankle place, the left and right sides in addition.Pressure transducer is positioned at host box, links to each other with cuff through the inducing QI sebific duct, and pressure transducer changes cuff air pressure into the corresponding signal of telecommunication.Fix on wrist portion to EGC sensor with the wrist clamping.
Embodiment 3: sensor site as shown in Figure 3 is adjacent to the skin of having smeared water or conductive paste.
Before beginning to detect, the detected person need do several times and deeply breathe, and it is even-tempered and good-humoured to accomplish, eupnea.When beginning to detect, inflator pump is given four cuff inflations, about 10 seconds; Equipment automatically identifies detected person's the highest systolic pressure, behind the pressure that appends 10～20mmHg on the basis of the highest systolic pressure that dopes again, stops inflation, venting then; Like this; The detected person does not have uncomfortable sensation, and through sensor acquisition signal, transmission, amplification, filtering, analog digital conversion and data analysis, testing in about 3～5 minutes is all over.The data of storing can at any time be called out and carry out examining report printing or data retrieval, also can carry out teledata through networking component and share.
Claims (3)
1. human body artery sclerosis nondestructive testing instrument; It comprises A/D modular converter, heart sound transducer, hear sounds pre-processing module, the elementary filtration module of hear sounds, pressure transducer, blood pressure signal amplification module under EGC sensor, electrocardio pre-processing module, the elementary filtration module of electrocardio, the Single-chip Controlling; It is characterized in that EGC sensor is connected pre-processing module separately respectively with heart sound transducer; Pre-processing module connects elementary filtration module separately more then; Connect single-chip microcomputer at last separately, said single-chip microcomputer also is connected with blood pressure signal amplification module and microcomputer, and the blood pressure signal amplification module connects pressure transducer.
2. according to the described human body artery sclerosis of claim 1 nondestructive testing instrument; It is characterized in that a human body arteriosclerosis nondestructive testing instrument host box connects the quadruplet cuff through the rubber conduit; Connect two through lead and detect cardiac electrical pick off; Connect a pick off that detects cardiechema signals through lead, and connect a microcomputer and a printer.
3. according to the described human body artery sclerosis of claim 2 nondestructive testing instrument; Its characteristic is to use the sharp printer of common non-special microcomputer, and the collection of data signal, secondary filtering noise reduction and data computation all realize through the software that is installed on the microcomputer.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011104427661A CN102512147A (en) | 2011-12-27 | 2011-12-27 | Non-destructive detector for human arteriosclerosis |
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| CN2011104427661A CN102512147A (en) | 2011-12-27 | 2011-12-27 | Non-destructive detector for human arteriosclerosis |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748038A (en) * | 2016-02-01 | 2016-07-13 | 山东大学 | Nondestructive testing device for coronary heart disease risk indexes |
| CN106419888A (en) * | 2016-10-27 | 2017-02-22 | 遵义医学院附属医院 | Real-time monitoring device for patients of department of cardiology |
| CN106991288A (en) * | 2017-04-06 | 2017-07-28 | 浙江大学 | Arteriosclerosis detecting method |
| WO2018133123A1 (en) * | 2017-01-23 | 2018-07-26 | 悦享趋势科技（北京）有限责任公司 | Method and device for processing pulse wave |
| CN109316177A (en) * | 2018-11-02 | 2019-02-12 | 杜玲娟 | A kind of assessment device and method for peripheral arterial disease hemadostewnosis degree |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1188635A (en) * | 1997-01-22 | 1998-07-29 | 张才德 | Heart function computer detection diagnostic instrument |
| CN201088580Y (en) * | 2007-11-02 | 2008-07-23 | 北京鑫悦琦科贸有限责任公司 | Arteriosclerosis surveymeter |
| CN201267466Y (en) * | 2008-05-29 | 2009-07-08 | 王培勇 | Arteriosclerosis detector |
-
2011
- 2011-12-27 CN CN2011104427661A patent/CN102512147A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1188635A (en) * | 1997-01-22 | 1998-07-29 | 张才德 | Heart function computer detection diagnostic instrument |
| CN201088580Y (en) * | 2007-11-02 | 2008-07-23 | 北京鑫悦琦科贸有限责任公司 | Arteriosclerosis surveymeter |
| CN201267466Y (en) * | 2008-05-29 | 2009-07-08 | 王培勇 | Arteriosclerosis detector |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748038A (en) * | 2016-02-01 | 2016-07-13 | 山东大学 | Nondestructive testing device for coronary heart disease risk indexes |
| CN105748038B (en) * | 2016-02-01 | 2017-02-15 | 山东大学 | Nondestructive testing device for coronary heart disease risk indexes |
| CN106419888A (en) * | 2016-10-27 | 2017-02-22 | 遵义医学院附属医院 | Real-time monitoring device for patients of department of cardiology |
| WO2018133123A1 (en) * | 2017-01-23 | 2018-07-26 | 悦享趋势科技（北京）有限责任公司 | Method and device for processing pulse wave |
| CN106991288A (en) * | 2017-04-06 | 2017-07-28 | 浙江大学 | Arteriosclerosis detecting method |
| CN109316177A (en) * | 2018-11-02 | 2019-02-12 | 杜玲娟 | A kind of assessment device and method for peripheral arterial disease hemadostewnosis degree |
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Application publication date: 20120627 |