CN102499727A - 'Duodenum-jejunum' absorption intestinal exclusion bypass sleeve - Google Patents

'Duodenum-jejunum' absorption intestinal exclusion bypass sleeve Download PDF

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Publication number
CN102499727A
CN102499727A CN2011103937722A CN201110393772A CN102499727A CN 102499727 A CN102499727 A CN 102499727A CN 2011103937722 A CN2011103937722 A CN 2011103937722A CN 201110393772 A CN201110393772 A CN 201110393772A CN 102499727 A CN102499727 A CN 102499727A
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China
Prior art keywords
intestinal
oversleeve
becket
flower appearance
flower
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Pending
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CN2011103937722A
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Chinese (zh)
Inventor
戴睿武
林宁
汤礼军
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Individual
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Individual
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Priority to CN2011103937722A priority Critical patent/CN102499727A/en
Publication of CN102499727A publication Critical patent/CN102499727A/en
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Abstract

The invention relates to an intestinal bypass sleeve, which is formed by connecting the tail end of a hollow sleeve structure and a foldable flower-shaped metal ring, and is characterized in that the tail end of the hollow sleeve structure is connected with the tail end of the folded flower-shaped metal ring; and the flower-shaped metal ring consists of five independent petal-shaped structures, and one petal-shaped structure consists of a memory metal ring and a non-absorbable silk thread positioned on the middle section of the ring. According to the intestinal bypass sleeve, the absorption of food and nutrition ingredients in duodenum and jejunum is reduced effectively by a non-invasive intestinal sleeve technology; and energy and nutrient are limited by an effect of reducing absorptivity to fulfill the aim of improving body weight, blood sugar and blood fat.

Description

" Duodeno-jejunum " absorbs the spacious oversleeve in the intestinal of putting
Technical field
The present invention relates to a kind of medical apparatus and instruments and method to set up thereof, reduce noinvasive medical apparatus and instruments and the method to set up thereof that the nutrient metabolism disorder was taken in and corrected to nutrient when particularly a kind of obesity or diabetes.
Background technology
Control energy and nutrient be in the absorption of duodenum and jejunum, and the secretion of controlling above-mentioned position Nutrition and Metabolism associated hormone is a key of improving metabolic complication such as fat and diabetes.
External through spacious duodenum and/or the jejunum epimere put of " stomach-duodenum " turn of tidal stream by-pass operation, suppress nutrient in the absorption at above-mentioned position and the secretion that changes nutrition associated metabolic hormone.Yet the bypass of operation turn of tidal stream can't be replied once changing, and this gastrointestinal structural change is nonvolatil, brings problems such as malnutrition for a long time in the past.
The intestinal sleeve is identical with the principle of turn of tidal stream operation, but utilizes the biomaterial pipeline to substitute intestinal, suppresses to absorb and hormone secretion, reduces wound simultaneously.
People such as M.Tarnoff published an article and research are set in the body of setting forth oversleeve (DJBS) in its Duodeno-jejunum intestinal in 2007, and this DJBS sends to through endoscope by one, can fix and expand the interior oversleeve structure that gets into jejunum at the duodenum near-end.As shown in Figure 4, this DJBS comprises sawtooth appearance ferrule 9, wire coil structure 10; The tail end 11 of sawtooth appearance ferrule and the oversleeve structure 4 of hollow, wherein two rhizoid lines have played the effect of keeping structure on the wire coil structure 10, when withdrawing device; Need cut off two rhizoid lines simultaneously; Under the tension force effect, the Nitinol ring flicks, and takes out down by scope.One section of this DJBS is can unfolded voluntarily Nitinol) fixture and the fluoropolymer oversleeve that is connected thereafter, this oversleeve can be expanded 60 centimetres in the near-end intestinal tube.The fixture part is the 25-50 millimeter at duodenum proximal spread diameter, and comprises overhead structure to stablize whole device.Seepage when the oversleeve structure can prevent that the stomach chyme from flowing through, thereby the spacious proximal small bowel of having put have fully caused the shunting of gallbladder pancreas.
But because the Nitinol ring of DJBS opens diameter is the 25-50 millimeter, and it is in pylorus, but in intestinal, internal diameter takes out damage intestinal easily down; DJBS Nitinol ring has two rhizoid lines in addition, takes out and need cut short two rhizoid lines, complicated operation simultaneously when external.
Summary of the invention
The present invention provides a kind of volume less, simple to operate, in the intestinal of easy damaged coat of the stomach or esophagus cover with and the method for placing.
Oversleeve is that oversleeve structure tail end by one section hollow connects the flower appearance becket that can fold and constitutes jointly in the oversleeve in a kind of intestinal, said intestinal; It is characterized in that described hollow the oversleeve structure end with folding after terminal connection of flower appearance becket; Described flower appearance becket is made up of five independent petal spline structures, and one of them petal is become with the not absorbability silk group that is positioned at the ring stage casing by the Memorability becket.
The deployed diameter of wherein said flower appearance becket is 1-2cm.
The oversleeve structure of wherein said hollow is made up of poly-lactic acid material, and described flower appearance becket constitutes for the Memorability titanium metal material.
The laying method of oversleeve in a kind of intestinal, oversleeve arises from pyloric ostium and extends in the intestinal in the described intestinal, is compressed into " folded umbrella " shape and is enclosed within outside the plastics transmission pipeline described flower appearance becket is inwardly folding in advance; Through placing the seal wire that finishes in advance is the path; With the plastics transmission pipeline and be enclosed within that oversleeve sent pyloric ostium to jejunum epimere in the intestinal in the outside, flower appearance becket arrives pyloric ostium by pusher, excite pusher after; Flower appearance becket is opened the formation umbrella naturally, and buckle is in pylorus gastric side; Plastics transmission pipeline and seal wire withdraw from external subsequently; Along the intestinal descending development, free end is also open in intestinal through chyme, water or gas effect for oversleeve in the intestinal in intestinal; Oversleeve has enough length to surpass the length of jejunum epimere as required to ensure free-end in the described intestinal.
Wherein said petal-shaped Memorability titanium ring is folding in advance, connects the oversleeve structure thereafter, and the two is enclosed within can be through the outer system that forms of the plastics transmission pipeline of seal wire; The direct view under endoscope seal wire is put into native system to reach the jejunum epimere through pylorus through seal wire.Be the exciter device between petal-shaped Memorability titanium ring and pusher, control head is at the pusher far-end, and it is descending that perspective confirms that down it stops when arriving pylorus, excite and open the petal-shaped becket, but and inlay card at stomach pylorus end; The lower end of plastics transmission pipeline is the knot that can be undone by a pull spline structure with sleeve shape pipeline enclosure, can both broken away from through pushing the exciter control head.
The oversleeve material is the poly-lactic acid material pipeline in the wherein said intestinal, and on the petal ring under affiliated pipeline tapping one end is socketed in, the other end can be open naturally after arrangement finishes, and forms path.
Wherein on the petal of petal-shaped Memorability titanium ring one section silk thread structure is arranged, during withdrawing device, cut off silk thread, it is external with the complete taking-up of oversleeve device under scope, to extract the broken ends of fractured bone.
A kind of intestinal internal bypass based on petal-shaped Memorability titanium ring is provided with; Comprise the petal-shaped Memorability titanium ring that can place in the intestinal; Described petal-shaped Memorability titanium ring can inwardly fold compression and be fixed into " petal " spline structure that the aperture is slightly larger than seal wire by the collar, delivers to pyloric ostium via seal wire, removes the collar with the terminal hook formation of seal wire when withdrawing from seal wire; Make the petal-shaped structure open buckle naturally in pylorus gastric side, sleeve shape pipeline gets in the intestinal.Along the intestinal descending development, another free end is in intestinal through chyme, water or gas effect.
Technical conceive of the present invention: through noninvasive intestinal oversleeve technology, effectively reduce the absorption of food and nutritional labeling, carry out the restriction of energy and nutrient, reach the purpose of improving body weight, blood glucose and blood fat through the effect that reduces absorbance at duodenum and jejunum.
Beneficial effect of the present invention:
(1) the becket diameter of oversleeve structure is 1-2cm in the intestinal of the present invention, compares existing apparatus, and is more easy to operate when installing and taking out, and can effectively avoid the damage to intestinal simultaneously; It is smaller and more exquisite that flower appearance becket is compared existing apparatus, better with gastropyloric applying degree;
(2) flower appearance becket of the present invention is made up of five independent petal spline structures; One of them petal is become with the not absorbability silk group that is positioned at the ring stage casing by the Memorability becket; Because only containing one section can not absorb silk thread; Get final product so only need cut short a rhizoid line when taking out, simple to operate;
(3) the oversleeve structure of hollow of the present invention is made up of poly-lactic acid material; Poly-lactic acid material is compared the interior oversleeve structure of existing polythene material; It is better that its biofacies is prone to property, and can carry out degraded in the intestinal, is fit to the long-term oversleeve structure in this said intestinal of placing.
Description of drawings
Fig. 1 flower appearance becket structural representation
Oversleeve structural representation in Fig. 2 intestinal
Oversleeve displacement structure sketch map in stomach and duodenum in Fig. 3 intestinal
Oversleeve structural representation in the external intestinal of Fig. 4
The specific embodiment
As depicted in figs. 1 and 2, oversleeve is that oversleeve structure 4 tail ends by one section hollow connect the flower appearance becket 2 that can fold and constitute jointly in the oversleeve in a kind of intestinal, said intestinal; It is characterized in that described hollow oversleeve structure 4 end with folding after 2 terminal connections of flower appearance becket; Described flower appearance becket is made up of five independent petal spline structures, and one of them petal is made up of Memorability becket and the not absorbability silk thread 1 that is positioned at the ring stage casing; The deployed diameter of wherein said flower appearance becket 2 is 1-2cm; The oversleeve structure 4 of wherein said hollow is made up of poly-lactic acid material, and described flower appearance becket 2 is that the Memorability titanium metal material constitutes;
The laying method of oversleeve in a kind of intestinal, oversleeve arises from pyloric ostium and extends in the intestinal in the described intestinal, is compressed into " folded umbrella " shape and is enclosed within outside the plastics transmission pipeline described flower appearance becket 2 is inwardly folding in advance; Through placing the seal wire that finishes in advance is the path; With the plastics transmission pipeline and be enclosed within that oversleeve sent pyloric ostium to jejunum epimere in the intestinal in the outside, flower appearance becket 2 arrives pyloric ostiums by pusher, excite pusher after; Flower appearance becket 2 is opened the formation umbrella naturally, and buckle is in pylorus gastric side; Plastics transmission pipeline and seal wire withdraw from external subsequently; Along the intestinal descending development, free end is also open in intestinal through chyme, water or gas effect for oversleeve in the intestinal in intestinal; Oversleeve has enough length to surpass the length of jejunum epimere as required to ensure free-end in the described intestinal;
As shown in Figure 3 at direct view under endoscope; The oversleeve structure arrives stomach cardia 5 in the intestinal of folding compression, opens to take advantage of a situation with cardia to get into body of stomach 6, down gets into stomach pylorus 7 again; Folding flower appearance becket 2 is opened in stomach pylorus 7, and open flower appearance becket 2 is fitted fixing with stomach pylorus 7.The oversleeve structure 4 that makes hollow through feeding water under the scope is along duodenum 8 descending opening, and length reaches the duodenum end.

Claims (6)

1. oversleeve in the intestinal, oversleeve is that oversleeve structure (4) tail end by one section hollow connects that a flower appearance becket (2) that can fold is common to be constituted in the said intestinal; It is characterized in that described hollow oversleeve structure (4) end with folding after terminal connection of flower appearance becket (2); Described flower appearance becket is made up of five independent petal spline structures, and one of them petal is made up of Memorability becket and the not absorbability silk thread (1) that is positioned at the ring stage casing.
2. oversleeve in the intestinal as claimed in claim 1, described flower appearance becket (2) deployed diameter is 1-2cm.
3. oversleeve in according to claim 1 or claim 2 the intestinal, the oversleeve structure (4) of described hollow is made up of poly-lactic acid material, and described flower appearance becket (2) is Memorability titanium metal material formation.
4. oversleeve in the intestinal as claimed in claim 1 is characterized in that oversleeve arises from pyloric ostium in the described intestinal to extend in the intestinal, is compressed into folding umbrella and is enclosed within outside the plastics transmission pipeline described flower appearance becket (2) is inwardly folding in advance; Through placing the seal wire that finishes in advance is the path; By pusher with the plastics transmission pipeline and be enclosed within the outside intestinal in oversleeve sent pyloric ostium to jejunum epimere; Flower appearance becket (2) arrives pyloric ostium; After exciter was excited, flower appearance becket (2) was opened the formation umbrella naturally, and buckle is at stomach pylorus end; Plastics transmission pipeline and seal wire withdraw from external subsequently; Along the intestinal descending development, free end is also open in intestinal through chyme, water or gas effect for oversleeve in the intestinal in intestinal; Oversleeve has enough length to surpass the length of jejunum epimere as required to ensure free-end in the described intestinal.
5. oversleeve in the intestinal as claimed in claim 4; It is characterized in that: described exciter is positioned between flower appearance becket (2) and the intestinal oversleeve; Control head is at the exciter far-end; It is descending that perspective confirms that flower appearance becket (2) stops when arriving pylorus down, excites and open flower appearance becket (2), and make flower appearance becket (2) inlay card at stomach pylorus end; Between the oversleeve structure (4) of the lower end of plastics transmission pipeline and hollow is the knot that can be undone by a pull spline structure, through pushing the pusher control head both is broken away from.
6. like oversleeve in claim 4 or the 5 described intestinals, it is characterized in that: when it is characterized in that taking out in the intestinal oversleeve, cut off not absorbability silk thread (1), an end that under scope, extracts absorbability silk thread not with intestinal in the complete taking-up of oversleeve external.
CN2011103937722A 2011-12-02 2011-12-02 'Duodenum-jejunum' absorption intestinal exclusion bypass sleeve Pending CN102499727A (en)

Priority Applications (1)

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CN102499727A true CN102499727A (en) 2012-06-20

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110325094A (en) * 2017-04-19 2019-10-11 Hoya株式会社 Mounting device at the top of endoscope

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201920790U (en) * 2010-12-20 2011-08-10 王志强 Sleeve for isolating small intestine from food
WO2011099940A1 (en) * 2010-02-11 2011-08-18 National University Of Singapore System, device, and process for modifying absorption of matter by a gastrointestinal wall
CN201987704U (en) * 2010-12-06 2011-09-28 北京畅想天行医疗技术有限公司 Duodenum-jejunum built-in cannula

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011099940A1 (en) * 2010-02-11 2011-08-18 National University Of Singapore System, device, and process for modifying absorption of matter by a gastrointestinal wall
CN201987704U (en) * 2010-12-06 2011-09-28 北京畅想天行医疗技术有限公司 Duodenum-jejunum built-in cannula
CN201920790U (en) * 2010-12-20 2011-08-10 王志强 Sleeve for isolating small intestine from food

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110325094A (en) * 2017-04-19 2019-10-11 Hoya株式会社 Mounting device at the top of endoscope

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Application publication date: 20120620