CN102451506A - Method and device for controlling airflow of respirator - Google Patents

Method and device for controlling airflow of respirator Download PDF

Info

Publication number
CN102451506A
CN102451506A CN2010105171499A CN201010517149A CN102451506A CN 102451506 A CN102451506 A CN 102451506A CN 2010105171499 A CN2010105171499 A CN 2010105171499A CN 201010517149 A CN201010517149 A CN 201010517149A CN 102451506 A CN102451506 A CN 102451506A
Authority
CN
China
Prior art keywords
ventilation
valve
tidal volume
flow
respirator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN2010105171499A
Other languages
Chinese (zh)
Other versions
CN102451506B (en
Inventor
袁含光
Original Assignee
袁含光
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 袁含光 filed Critical 袁含光
Priority to CN201010517149.9A priority Critical patent/CN102451506B/en
Publication of CN102451506A publication Critical patent/CN102451506A/en
Application granted granted Critical
Publication of CN102451506B publication Critical patent/CN102451506B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The invention discloses a method for controlling the airflow of a respirator. The method comprises the following steps of: introducing continuous airflow with a stable flow rate into a respirator system through an air source; and dynamically adjusting ventilation rhythm and ventilation strength in an air passage by controlling the valve movement frequency and distance of an airflow outlet end so as to support the respiration of a patient. In the method, a command ventilation mode and an autonomous respiration operating mode are utilized; if respiration is stopped in the autonomous respiration mode, autonomous respiration can be maintained in a mode of reducing target tidal volume; and the respiration is still stopped when the tidal volume is reduced to a preset value, so that central pathological changes are determined, and the autonomous respiration operating mode is converted into the command ventilation operating mode. The invention also discloses a device for controlling the airflow of the respirator. In the method and the device, an independent and integral respirator system which completely uses positive pressure switching ventilation of the air passage as a technical basis is formed by a series of matched regulation modes such as a target tidal volume automatic regulation mode, the autonomous respiration mode, the command ventilation operating mode, a respiration pause automatic processing mode and the like.

Description

A kind of respirator flow controlling method of air and control device
Technical field
The present invention relates to a kind of artificial respirator, particularly a kind of respirator continuous flow control method and control device.
Background technology
Respirator is a kind of crucial life support equipment that ventilation and oxygenate support are provided for the respiratory failure patient.At present, simulated respiration action is all adopted in the work of main flow respirator, that is to say, relies on respirator that patient airway is carried out positive pressure gas infusate flow periodically and comes for lung full the respiratory drive support to be provided.With regard to the respirator technology, improve and breathe the quality of supporting, will reduce the airway pressure and the work of breathing consumption of breathing when supporting as far as possible, just must improve the synchronicity and the harmony of respirator work and patient's autonomous respiration.Though modern respirator is obtained certain technological progress in these areas; But during owing to the analogue type ventilation; Patient's autonomous respiration is periodic and the output of respirator air-flow also is periodic, make respirator work can obey patient's autonomous respiration fully, just must make these two highly dynamic processes fully synchronously and coordinations; This just requires quite the air-flow control technology and expensive cost of manufacture of complicacy, and is difficult to realize synchronous fully and coordination between the two.
Capacity type ventilation of the prior art and pressure-type ventilation are the basic ventilation support schemes of two types of modern main respirator.These two types of ventilating modes are all periodically sent into the malleation air-flow by respirator work source of the gas and are come to patient pressure support to be provided in air flue.Because patient's breath is periodic; And; Patient's air flue and lungs are complicated pipeline system, thus respirator air-flow output must the setting of the exciting of air-flow output, flow and variation, the time various aspects such as phase transformation, airway pressure and tidal volume cooperate patient air-breathing needs, obey the instant variation of its air flue frictional resistance and breast, lung tissue compliance; The setting of any of these index is improper, all possibly cause patient's discomfort, too high airway pressure in addition with the antagonism of respirator.
These shortcomings are in capacity type ventilation working method, particularly complicated and serious patient shows particularly outstandingly in the air flue pathological changes because the flow output of capacity type ventilation be set and not with air flue situation and patient inhales need variation change.Clear and definite now, too high airway pressure is the main cause that causes the respirator injury of lung.So improving safety, ventilation efficiency and the comfortableness of respirator treatment is the focus of attention of respirator technology and respirator treatment always, the purpose of its exploration and the result who brings, the reduction of airway pressure just.
Over the past two decades, the extensive use that comprises the pressure-type ventilating mode of pressure support ventilalion and pressure controlled ventilation is the most important technological progress of mechanical ventilation.The air-flow output of pressure-type ventilating mode can be obeyed the performance of air flue situation and air-breathing needs preferably; Reduced significantly patient airway pressure, improved patient's comfortableness; Otherwise; If still adopt the volum-controlled type ventilating mode, especially the patient of serious lung, air flue pathological changes, breathing is supported more difficult to deal with for most cases.
No matter be ventilation of capacity type or pressure-type ventilation; Ventilatory effect all depends on the interaction of malleation air-flow and air flue situation; The generation of malleation air-flow and output all are periodic; Periodically be pressed in the process of air flue at the malleation air-flow, be difficult to avoid fully and patient's air flue situation and the situation that do not match between the air-breathing needs.
In recent years, the new working method that Bi-level by name on some respirator, occurred.Bi-level can be very easy to, very rapidly alleviate respirator patient's breath difficulty and need not the help of downern; Simultaneously, under the prerequisite that obtains same level ventilation capacity, the airway pressure that Bi-level caused will be starkly lower than conventional ventilation mode even pressure support ventilalion and pressure controlled ventilation mode.The practical manifestation of Bi-level clinical practice has embodied its good aeration quality.
The present inventor has proposed a kind of notion of Positive Airway Pressure switch type ventilating mode based on the work of Bi-level.Positive Airway Pressure switch ventilation be a kind of and current capacity type ventilation and pressure-type ventilate two types of main flow ventilating modes diverse, be the ventilating mode of working foundation with continuous flow terminal current limiting mechanism.The work source of the gas that Positive Airway Pressure switches ventilation provides the high flow capacity continuous flow to tubing, and when air-flow is set at the resistance that produces on the pressure valve of system terminal opening when limiting, the interior pressure of whole tubing will correspondingly raise.Patient airway and respirator pipeline connect and are same system during respirator treatment, when air motion stops in air-breathing end and the end-tidal air flue, comprise in the system that the pressure of air flue all is in same level, so system pressure is being represented air flue and intrapulmonic pressure power; Positive Airway Pressure switches system pressure that ventilation caused and switches the reality intrinsic pressure switching with intrapulmonic pressure power of air flue just.As an elastic cavity, the variation of the capacity of lung always changes along with the pressure in the lung, and both relations show as pressure volume curve.On pressure volume curve, higher airway pressure and intrapulmonic pressure power are always being represented bigger lung capacity.When Positive Airway Pressure switched ventilation, airway pressure switched on two different height and has also just caused the corresponding conversion of lung capacity at two varying levels in the lung, and this is just meaning the carrying out of ventilation.
Improving ventilation is two basic purposes of respirator treatment with oxygenate, and the physiology is last, and these two processes are relevant with ventilation capacity and pulmonary function residual volume respectively.When Positive Airway Pressure switched ventilation, venting pressure was determining the size of the capacity of ventilating, and the air flue pressure of foundation is then determining the size of pulmonary function residual volume, so these two indexs are the most important indexs of breathing in supporting.
Positive Airway Pressure switches the variation that the principle of ventilating is similar to water level in the reservoir, and streamflow is retained by dam, and upper pond level improves naturally, and the height of gate is determining the water level in the storehouse.When Positive Airway Pressure switches ventilation; The volume change of lung is not directly to cause because intermittent air-flow is admitted in the lung; But the indirect consequence of following whole respirator pipeline pressure to change; The volume change that breathing machine ventilation causes does not receive the influence of patient respiration action, thereby no longer has the matching problem of the output of respirator air-flow and patient airway situation and air-breathing needs.
Bi-level is so far still as on a kind of main flow respirator that is configured in the advanced person who is the basis with capacity type ventilating mode and pressure-type ventilating mode than minor working method; The also still simple time of the conversion of its pressure switches, and promptly carries out conversion and control with frequency and the time ratio that is provided with in advance.
The progress of modern critical illness intensive medicine is making the chance that the patient of increasing serious lung, air flue pathological changes has had breathing and life to support, thereby, also increasingly high to the requirement of safety, effectiveness and the comfortableness of respirator treatment; Airway pressure when reducing the ventilation support as far as possible; Let patient's the work of the leading respirator of autonomous respiration as far as possible; Making the work of respirator more can obey patient's needs, becoming the new trend in the respirator treatment, also is the new requirement to the respirator technical development.The actual performance of Bi-level shows that the ventilation of Positive Airway Pressure switch type will be the new technique direction that ventilation is supported; With the Positive Airway Pressure switch type ventilating mode needs that to further develop, improve into a kind of independently novel respirator will be technology and clinical development.
Summary of the invention
The present invention is in order to overcome defective in the above-mentioned prior art, through mandatory ventilation and autonomous respiration working method, target tidal volume auto-control, asphyxia automatically a series of supporting regulation and control such as disposals form and a kind ofly switch with Positive Airway Pressure fully that to ventilate be independence and the complete respirator system of technical foundation.
The present invention provides a kind of respirator flow controlling method of air; The continuous flow of stability of flow is imported respirator system by source of the gas; And through the valve travel frequency of control airflow outlet end with apart from ventilation rhythm and the ventilation dynamics dynamically adjusted in the air flue; Thereby realize the breathing support to the patient, comprise following two kinds of mode of operations: the mandatory ventilation mode of operation is used for unstable or use when providing the ventilation of specified level to support for the patient in the patient respiratory impulsion; Under the mandatory ventilation mode of operation; The dynamic adjustment of the correction that central processing unit is ordered according to the base position A of said valve and the displacement B of valve, by-pass valve control moves at point-to-point transmission with frequency preset, thus the target tidal volume of in venting process, keeping setting provides mandatory ventilation support for the patient; The autonomous respiration mode of operation; Confirm the beginning and the termination of patient's aspiratory action through dynamic pressure of air flue interface section and flow detection; The dynamic adjustment of the correction that the base position A of realization valve is ordered and the displacement B of valve; Central processing unit moves at point-to-point transmission with patient's autonomous respiration rhythm by-pass valve control according to said correction and adjustment result; Make the pressure in the air flue switch the respiratory movement of being obedient to the patient fully, in venting process, keep the target tidal volume of setting or when respiratory standstill appears in the patient, reduce the target tidal volume adaptively to keep the ventilation support of autonomous respiration.
Wherein, The mandatory ventilation mode of operation comprises the steps: mandatory ventilation frequency and breathing time ratio, target tidal volume and baseline airway are compressed into the line parameter setting and the target tidal volume and the baseline airway that are provided with are pressed the displacement key element that is converted into valve, and said valve displacement key element is base position A and displacement B; Based on the displacement key element of said valve, central processing unit control starts first ventilation; In first venting process; Instantaneous delivery and airway pressure to the air flue interface section detect; And based on the actual pressure that records with data on flows is analyzed and computing, draw the displacement B of A point position and adjusted valve after the calibration respectively and with its valve displacement key element as the initial ventilation of target tidal volume; Central processing unit control starts the target tidal volume and initially ventilates; Be based in the first venting process A point position and adjusted valve displacement B after the calibration of confirming, and compare the said initial ventilation of execution with predefined said mandatory ventilation frequency and breathing time; After initial the ventilation, continue the ventilation of target tidal volume and press the A point position and the displacement B that adjusts valve of recalibration valve periodically one by one, this dynamic calibration and adjustment are through change or the termination of whole ventilation supporting process until mandatory ventilation.
Wherein, The autonomous respiration mode of operation comprises the steps: target tidal volume, baseline airway pressure and inspiratory phase trigger sensitivity, expiratory phase converting sensitivity are carried out the parameter setting and target tidal volume that is provided with and baseline airway are pressed the displacement key element that is converted into valve, and said valve displacement key element is base position A and displacement B; The detection of autonomous respiration inhalation flow and processing; When the changes in flow rate characteristic of detected autonomous air-breathing beginning in the time of setting satisfies the said inspiratory phase trigger sensitivity threshold value of setting; Judge air-breathing beginning; According to the displacement key element of said valve, central processing unit control starts first ventilation, and valve begins to move to B from the A point; When detected flow drops to the expiratory phase converting sensitivity threshold value of setting, judge the beginning of exhaling, central processing unit instruction this moment valve returns the A point in moment; In first venting process; Instantaneous delivery and airway pressure to the air flue interface section detect; And according to the actual pressure that records with data on flows is analyzed and computing, draw the displacement B of A point position and adjusted valve after the calibration respectively and with its valve displacement key element as the initial ventilation of target tidal volume; When detecting changes in flow rate characteristic that autonomous respiration begins in the said setting-up time after first ventilation beginning once more and satisfy the said inspiratory phase trigger sensitivity threshold value of setting; Central processing unit control starts the target tidal volume and initially ventilates; According to A point position and the adjusted valve displacement B after the calibration of in first venting process, confirming, and carry out said target tidal volume with patient's self breath rhythm and initially ventilate; After the initial ventilation; Continue the ventilation of target tidal volume and one by one by the A point position of recalibration valve and the displacement B of adjustment valve periodically, this dynamic calibration and adjusting through change or the termination of the ventilation supporting process of whole autonomous respiration until the autonomous respiration work process.
Wherein, Under the autonomous respiration mode of operation; Respiratory standstill appears first in the time of setting; Then implement the once command ventilation, when autonomous respiration rhythm recovers to stablize, continue the target tidal volume ventilation of the former setting of autonomous respiration mode by the valve displacement key element in the last time autonomous respiration mode of operation; Respiratory standstill appears once more in the time of setting; Then implement the once command ventilation by the target tidal volume behind the downward modulation certain proportion; The valve displacement key element of this moment is calculated modification in proportion; When autonomous respiration rhythm recovers stablize, continue the target tidal volume of keeping after the downward modulation of autonomous respiration mode and ventilate; Asphyxia still appears in the time of setting; Then further a certain proportion of target tidal volume of downward modulation is implemented the once command ventilation; The valve displacement key element of this moment is still calculated in proportion and is revised; If it is stable that autonomous respiration rhythm recovers, then continue the target tidal volume ventilation after reducing once more of keeping of autonomous respiration mode; If still can not eliminate asphyxia, judge that then asphyxia is due to the central pathological changes, this moment of enabled instruction immediately ventilation mode of operation is also pressed and target tidal volume parameter is carried out mandatory ventilation with the baseline airway of initial setting.
The present invention also provides a kind of respirator air flow controller, comprises source of the gas, central processing unit and resistance valve therein that is positioned at the air flue port of export and valve positioner that continuous flow can be provided, also comprises mandatory ventilation control chip and autonomous respiration control chip; Wherein, Frequency and inspiratory to expiratory ratio that the mandatory ventilation control chip moves by the parameter by-pass valve control of setting; And according to the pressure that is positioned at the patient airway interface section, the real-time detected pressure of flow transducer, data on flows, in venting process dynamically the A of calibration valve point position and the adjustment valve displacement B; Said central processing unit moves at point-to-point transmission through the valve positioner by-pass valve control according to each result who proofreaies and correct and adjust and with frequency preset, thereby the target tidal volume of in venting process, keeping setting provides mandatory ventilation support for the patient; The autonomous respiration control chip is through the setting of parameter and the real-time detected pressure of pressure, flow transducer, the data on flows that is positioned at the patient airway interface section; Confirm the beginning and the termination of patient's aspiratory action; And the dynamic adjustment of the displacement B of the base position A that realizes valve correction of ordering and valve; Central processing unit moves at point-to-point transmission according to proofreading and correct and adjust the autonomous respiration rhythm by-pass valve control of result with the patient; Make the pressure in the air flue switch the respiratory movement of being obedient to the patient fully, in venting process, keep the target tidal volume of setting or when respiratory standstill appears in the patient, reduce the target tidal volume adaptively to keep the ventilation support of autonomous respiration.
Compared with prior art; Respirator flow controlling method of air of the present invention and control device have two kinds of mode of operations; Can be the patient different breathing supports be provided, use that continuous flow avoided that air-flow intermittently brings with breathe comparatively complicated problems of asynchronous and equipment, specific as follows:
1, under the mandatory ventilation pattern; Central processing unit sends instruction according to valve base position A point and valve displacement B to the controller of the resistance valve therein of respirator; With frequency preset valve was moved between 2 o'clock, thereby mandatory ventilation support is provided patient.This pattern is to breathing the unsettled patient of impulsion the working method of ventilating and selecting when supporting being provided, to guarantee the unlikely respiratory standstill that on respirator, takes place of patient; Perhaps, select to be used for patient is provided the ventilation support of specified level during according to the state of an illness and treatment needs, this controlled working method is indispensable for the respirator of equipping as the life support.
2, under autonomous respiration mode; Central processing unit is through detecting the changes in flow rate that gets into patient airway; Come the controller of respirator resistance valve therein is sent instruction; Make the ventilation action of machine synchronous, and maintain the target level of setting through the tidal volume that the auto-control to valve location makes respirator provide patient to patient's breath action maintenance; If judge in this pattern and breathe long-time the pause, can support autonomous respiration through the mode that reduces the target tidal volume, if still do not have the autonomous respiration sign, then can change the mandatory ventilation pattern over to the patient is breathed support through the mode that reduces the target tidal volume.
Description of drawings
Fig. 1 is the current-controlled operation principle sketch map of respirator of the present invention;
Fig. 2 is the flow chart under the respirator mandatory ventilation mode of operation of the present invention;
Fig. 3 is the flow chart under the respirator autonomous respiration mode of operation of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing, several specific embodiment of the present invention are described in detail, but are to be understood that protection scope of the present invention does not receive the restriction of the specific embodiment.
At first introduce the ventilation operation principle of respirator of the present invention:
The high flow capacity air-flow of stability of flow is by source of the gas (being the blower fan air-supply) output entering system, because the resistance valves of airflow outlet end has limited the air-flow outflow, just formation is higher than atmospheric malleation in system.Like this, through the switching degree change (promptly controlling the resistance transfer of resistance valves) of resistance valves, can comprise in system correspondingly that the pressure that causes two differing heights in main airway and the lung switches.Because the lung of human body has elasticity, different intrapulmonic pressure height just means different lung capacity sizes.When resistance valves moved to the main airway port of export, main airway pressure raise, the also corresponding rising of intrapulmonic pressure power and capacity, and therefore lung obtains full; In case resistance valves is return initial position fast; Main airway pressure descends rapidly, the also corresponding quick decline of intrapulmonic pressure power, and the interior air-flow of lung this moment will return main airway under the compressing of lung tissue elastical retraction; The air-flow evacuation procedure of beginning expiratory phase stops until the emptying air-flow.System pressure highly constantly switches at corresponding two, just causes lung to fill with the continuous of emptying state and replaces, and this is called venting process on the physiology; Tolerance when filling with emptying changes, and passes in and out the capacity of lung exactly, i.e. tidal volume.
The switching controls of resistance valves comprises rhythm control and dynamics control, and rhythm control refers to the control of resistance switching way, frequency and rhythm; Dynamics control refers to the control of difference between high lower resistance, and it has embodied the dynamics that ventilation is supported, shows as the size of tidal volume.
As shown in Figure 1, resistance valves, i.e. the switching degree of respirator master control valve (hereinafter to be referred as valve) is determining the conversion of internal system main airway pressure.For example: valve opening when the A point is maximum, so the valve atmospheric pressure that internal system is kept when this position is minimum, and this pressure is called " baseline airway pressure "; When valve from A when B moves, valve openings is dwindled thereupon, the resistance that valve produces increases with corresponding internal system pressure, promptly valve openings A, B point-to-point transmission move the conversion with direct control system pressure.Therefore, the A determining positions of ordering the baseline airway height of pressing; Distance between A point to the B point has determined the change in elevation (being amplitude of variation) of airway pressure, the dynamics of just ventilating or ventilation intensity; The interval that switches between A point to the B point has determined the rhythm that switches to control.Be above-mentioned dynamics control and rhythm control.
Introduce respirator of the present invention below in two kinds of mode of operations that adopt under the prerequisite of above-mentioned ventilation principle: i.e. mandatory ventilation mode of operation and autonomous respiration mode of operation.
The mandatory ventilation mode of operation is that patient is carried out commands for controlling on the rhythm of dynamics that ventilation is supported and full-emptying.This pattern is to breathing the unsettled patient of impulsion the working method of ventilating and selecting when supporting being provided, to guarantee the unlikely respiratory standstill that on respirator, takes place of patient; Perhaps, select to be used for patient is provided the ventilation support of specified level during according to the state of an illness and treatment needs, this controlled working method is indispensable for the respirator of equipping as the life support.Specifically, under the mandatory ventilation pattern, through the frequency and the time ratio of " mandatory ventilation control chip " by-pass valve control evolution between A, B; And pass through " target tidal volume regulation and control module " control valve transformed distances between A, B.
The autonomous respiration mode of operation is to control resistance to outflow with patient's autonomous respiration to switch, thus the working method of control Positive Airway Pressure level.The realization of this pattern is beginning and the termination of being confirmed the patient inhales action by the changes in flow rate in the patient interface section, and controls the opening degree of resistance valves with this.When adopting the autonomous respiration working method, the patient's breath action is obedient in the switching of airway pressure fully, and the ventilation support of the most comfortable can be provided for patient.Specifically, the particular flow rate of this model selection entering patient airway changes starting point and the terminating point of confirming the breathing cycle as index; Come by-pass valve control moving between A, B through " autonomous respiration control chip ", its frequency and time ratio change with patient's autonomous respiration; And the transformed distances of valve between A, B still regulated and control by " target tidal volume regulation and control module ".
Therefore, no matter be instruction ventilation mode of operation or autonomous respiration mode of operation, all need come through the action of valve the rhythm and the dynamics of ventilation are controlled.Wherein, the time point that is moved between AB by valve (or the action conversion constantly) decides ventilation rhythm (how); The moving displacement of valve then determines the size (how much) of the dynamics of ventilating, and promptly how many valves moves, and where moves to, and this is accomplished by target tidal volume regulation and control chip, and it is used for control ventilation intensity (dynamics of ventilating in other words).The combined effect of above-mentioned just two indexs has determined reciprocating motion rule and the track of valve between AB.
Be elaborated in the face of the mandatory ventilation pattern down:
Mandatory ventilation pattern embodiment
Mainly form under the mandatory ventilation pattern by three operational modules; I.e. " time phase control module ", " baseline airway is pressed (PEEP) control module " and " target tidal volume regulation and control module ", three modules complete operation control task under the coordinated management of central processing unit.See also the implementation step that Fig. 2 specifies this pattern below:
Step 1 is selected entry instruction ventilation mode of operation by control panel;
Step 2, the running parameter setting:
Panel prompting by completing steps 1 back is shown is provided with parameter item by item.The parameter that needs to be provided with comprises: " mandatory ventilation frequency and breathing time ratio ", " target tidal volume " and " baseline airway pressure ";
Press the base position that can determine valve according to the baseline airway that is provided with.After baseline airway press to be set, " baseline airway pressure-controlled module " will be in view of the above by design data preset in the module, i.e. the A point position of airway pressure 10 centimeter water columns, and calculating corresponding valve base position is the A0 point;
" time phase control module " will by being provided with of " mandatory ventilation frequency and breathing time than " set up valve the travel frequency between 2 of the A, B and round time ratio;
Step 3 starts ventilation for the first time:
Central processing unit sends instruction, according to the valve displacement key element of setting in the step 2, ventilates for the first time.At this moment,
" time phase control module " be 2 mandatory ventilation frequency and the breathing time ratios set set by step, provide from the A point and move to the B point, return the time that A orders then and control;
Valve A point position by " baseline airway pressing mold piece " set by step 2 setting provide through calculating.Be valve 2 " baseline airway pressing mold pieces " the A0 point position of being calculated set by step, move to this base position;
Valve displacement (being the distance of A-B, hereinafter to be referred as displacement B) is then provided by initialize data by " target tidal volume regulation and control module ".This design data presets in this module, can make the normal person obtain the tidal volume about 300 to 500 milliliters, and displacement B is a starting point with the A0 position;
Step 4, flow and pressure detecting in the first venting process:
The flow transducer and the pressure transducer that are arranged in the air flue interface section detect instantaneous delivery and the airway pressure that whole venting process gets into the air flue interface section;
Flow transducer flows to instantaneous flow rate signal " flow processing module ", is decomposed into the flow curve data of actual entering air flue and because is possibly had two kinds of compositions of minimum flow data of revealing and causing by it.Flow signal is carried out Filtering Processing; The filling phase curve that is each ventilation cycle can be decomposed into the sawtooth waveforms on top and the rectangular base two parts that possibly exist; The sawtooth waveforms of its middle and upper part is the real airflow signal that gets in the air flue; And the rectangular base height is the elementary streams value, the leakage flow that reflection pipe joint position possibly occur.This sawtooth waveforms is transported to " tidal volume computing module " again, draws total tolerance that full process gets into air flue, i.e. tidal volume by this module arithmetic;
The detected pressure signal of pressure transducer is then sent into " baseline airway pressure-controlled module ", provides practical basis airway pressure measured value;
Step 5, the valve displacement of the initial ventilation of target tidal volume is confirmed:
After first gas valve returns the A point; " target tidal volume regulation and control module " is immediately by the target tidal volume of setting; First ventilation tidal volume actual result based on the preset valve displacement and the step 4 " tidal volume computing module " of first ventilation execution are calculated calculates to obtaining the initial value B0 of the required valve displacement of target setting tidal volume;
Step 6, the calibration that baseline airway is pressed:
" baseline airway pressure-controlled module " be 4 measured practical basis airway pressures set by step, and A point position is calibrated.The practical basis airway pressure for " time phase control module " send valve before the move of B point at once, by the pressure that pressure transducer is measured in the patient airway interface section, the pressure of this point should be the floor level in the whole ventilation cycle.The calibration that baseline airway is pressed is to realize that through the A point position of valve among adjustment Fig. 1 its detailed process is:
Detected pressure signal input " baseline airway pressure-controlled module " is compared with the baseline airway pressure that step 2 is provided with: if both errors≤± 3% then simply adopts the A0 result of calculation in the step 2; Like both errors>± 3%, then need recomputate according to the observed pressure and the A point position of first ventilation and valve block are moved to the Ax position;
Step 7 starts the target tidal volume and initially ventilates:
Calculate the A point position and the shift length B0 of adjustment according to step 5 and step 6, send instruction, carry out the target tidal volume and initially ventilate by central processing unit.
First ventilation obtains the most key patient's real data for the enforcement of target tidal volume, and promptly the quantum of patient's tidal volume and valve displacement concerns, therefore the regulation and control of target tidal volume just have the general foundation of enforcement.The target tidal volume is initially ventilated, and leading by " target tidal volume regulation and control module ", its key element is:
A. standard base airway pressure, promptly " baseline airway pressure-controlled module " according to the calibration result of abovementioned steps 6, confirmed the original position Ax that valve moves;
B. first target tidal volume valve displacement of establishing; The valve displacement B of i.e. " target tidal volume control module " first ventilation tidal volume of calculating based on step 5 and first ventilation calculates and is the required valve displacement B0 of the target tidal volume that obtains setting;
C. frequency and the breathing time ratio set promptly under the setpoint frequency in " time phase control module " and Shi Bi instruction, begin valve from the mobile B0 of Ax point, turn back to the action of initially ventilating of target tidal volume that Ax orders then;
Step 8, the continuation of target tidal volume ventilation:
After the initial ventilation of target tidal volume, mandatory ventilation valve working key element is constructed completion.But; Because the influence of factors such as dynamic and static resistance of many respiratory tracts and breath state; The quantitative relation of the full pressure of patient's tidal volume and air flue is constantly to change; Keeping the stable of target tidal volume just needs corresponding at any time adjustment valve displacement promptly to adjust the full pressure of air flue, and these regulation and control need continue the whole ventilation supporting process that patient Yu accepts respirator treatment, and " target tidal volume module " is exactly to have embodied this microcomputer technology that calculates regulation and control one by one automatically.
Promptly after step 7; Constantly press cycle repeating step 4 one by one to step 7; Press last time valve displacement and the next valve displacement Bx of actual tidal volume adjustment, promptly in target tidal volume venting process, dynamically carry out the adjustment of valve displacement and the calibration that baseline airway is pressed repeatedly.Begin from this step; The process of respirator work gets into the circulation of " action-measurement-calculating-adjustment-action again ", and promptly repeat: what flow and pressure detecting-baseline airway was pressed calibrate-adjusts valve displacement once more once more to carry out the mandatory ventilation of target tidal volume next time;
Step 9, the change of mandatory ventilation or termination:
Promptly, adjust accordingly by setting again until changing any parameter setting; Perhaps some cut-out work on aforementioned any step.
In sum; Under the mandatory ventilation pattern; Central processing unit sends instruction according to valve base position A point and valve displacement B to the controller of the resistance valve therein of respirator, with frequency preset valve is moved between 2 o'clock, thereby to patient mandatory ventilation support is provided.This pattern is to breathing the unsettled patient of impulsion the working method of ventilating and selecting when supporting being provided, to guarantee the unlikely respiratory standstill that on respirator, takes place of patient; Perhaps, select to be used for patient is provided the ventilation support of specified level during according to the state of an illness and treatment needs, this controlled working method is indispensable for the respirator of equipping as the life support.
Autonomous respiration mode of operation embodiment:
Mainly form under the autonomous respiration mode of operation by five operational modules; I.e. " baseline airway press (PEEP) control module ", " target tidal volume regulation and control module " and " inspiratory phase modular converter ", " expiratory phase modular converter " and " respiratory standstill is disposed module automatically ", five modules complete operation control task under the coordinated management of central processing unit.See also the implementation step that Fig. 3 specifies this pattern below:
Step 1 selects to get into the autonomous respiration mode of operation by control panel;
Step 2, the providing of running parameter setting and valve motion key element:
The setting of autonomous respiration mode of operation parameter comprises: " target tidal volume ", " baseline airway pressure " and " inspiratory phase trigger sensitivity " and " expiratory phase converting sensitivity ".
Step 201, " baseline airway pressure-controlled module " are made the A0 point position of valve:
After baseline airway was pressed and set, " baseline airway pressure-controlled module " calculated baseline airway and presses the corresponding A0 point of setting value position according to the design data that is preset at 10 centimeter water column A point positions in the module;
Step 202 provides the valve displacement of the first ventilation of presetting:
" target tidal volume control module " provides the design data that is preset at first gas valve displacement B in the module;
Step 203 is provided with inspiratory phase and triggers zero sensitivity:
The inspiratory phase trigger sensitivity is arranged on 2 liters/minute automatically, the range of choice be the 1-12 liter/minute, the expression with respect to before the air-breathing beginning at once the flow value of minimum flow be the inhalation flow of patient airway interface section.
When " flow processing module " detects the inhalation flow that gets into the patient airway interface section and the flow rising variation characteristic of the air-breathing beginning of autonomous respiration and activation threshold value that flow reaches this setting occur meeting; Provide instruction by central processing unit, trigger valve and begin to move;
Step 204 is provided with the expiratory phase converting sensitivity:
The expiratory phase converting sensitivity is arranged on 0 liter/minute automatically, the range of choice be the 0-10 liter/minute, expression is with respect at once full flow value before the air-breathing beginning.
Full flow in " flow processing module " detects the patient airway interface section of entering drop to with respect to air-breathing beginning before during at once flow value, send instruction by central processing unit, valve is return the A point immediately;
Step 3 is joined patient airway and respirator pipeline;
Step 4, the detection of inhalation flow and processing:
The flow transducer that is arranged in the patient interface section begins to detect the turnover flow in this section;
The instantaneous flow rate signal input " flow processing module " that detects is carried out Filtering Processing to flow curve, and the filling phase curve in each ventilation cycle can be decomposed into the sawtooth waveforms on top and the rectangular base two parts that possibly exist.The sawtooth waveforms on top is the real airflow signal that gets in the air flue, and sawtooth signal is carried out integral operation by " tidal volume compute chip ", calculates the total tolerance that gets in the lung, i.e. tidal volume; The rectangular base height is the elementary streams value, the leakage flow that reflection pipe joint position possibly occur;
Step 5, first ventilation and follow-up adjustment:
If in 10 seconds; When the valve that " flow processing module " detects changes in flow rate characteristic and the setting of the defined autonomous air-breathing beginning of step 203 moves activation threshold value (reaching 2 liters/timesharing); It is full that central processing unit instruction valve begins to move, carries out air flue, and the parameter of first ventilation is step 201,202,203 and 204 decisions;
Subsequently, when full flow drops to the defined expiration switching stream of step 204 value (reaching 0 liter/timesharing), central processing unit promptly instructs valve to return the A point in moment.
In the first venting process, flow is collected measured data with pressure transducer, is the target tidal volume foundation that action adjusts of initially ventilating as ventilation next time:
Step 501, the calibration that baseline airway is pressed:
The calibration that baseline airway is pressed is through " baseline airway pressure-controlled module " adjustment of the A point position of the valve block among Fig. 1 to be realized that its process is:
At once, the pressure that is measured in the patient airway interface section by pressure transducer is the practical basis airway pressure before " flow processing module " detects autonomous respiration appearance beginning, and the pressure of this point should be the floor level in the whole ventilation cycle.This pressure signal is imported " baseline airway pressure-controlled module ", and compresses into the row contrast with the baseline airway that step 201 is set: if both errors≤± 3%, then the baseline airway pressure of execution in step 201 settings; If both errors>± 3%, then need recomputate according to the observed pressure and the A point position of first ventilation and valve are moved to the Ax position;
Step 502, the providing of the initial gas valve displacement of target tidal volume:
Through aforementioned first ventilation; Obtain this patient's tidal volume and the airway pressure of being controlled by valve displacement and change between the two roughly data of dependency relation; " target tidal volume control module " can be calculated the required valve displacement of target tidal volume in view of the above, can begin the venting process of target tidal volume thus.Specific as follows:
After valve is return the A point; " flow processing module " imported " target tidal volume control module " with the inspiratory phase flow integral operation result after Filtering Processing; Carry out the initialization computing; According to the valve displacement B and the actual tidal volume that obtains of first ventilation, pro rata is calculated the required valve displacement B0 of target tidal volume of setting, is the valve moving parameter of the initial ventilation of target tidal volume as ventilation next time;
Step 6, the target tidal volume is initially ventilated:
If when detecting the valve of changes in flow rate characteristic that autonomous respiration begins and setting in 10 seconds after first ventilation beginning once more and moving activation threshold value; Central processing unit promptly provides instruction; Begin to move that (promptly begin initial venting process, the valve motion key element of this moment: A point position is Ax by the target tidal volume instruction valve of setting; B point displacement is B0; )
Step 601, repeating step 501 in initial venting process, it is that valve base position Ax calibrates that baseline airway is pressed;
Step 602, repeating step 502 in initial venting process, Bx regulates and control to valve displacement, to keep the target tidal volume of setting;
Step 7, continue the target tidal volume ventilation of autonomous respiration mode:
If the autonomous respiration even pace, promptly continuous repeating step 6 is until changing running parameter or changing the respirator mode of operation;
Step 8, the automatic disposal of respiratory standstill:
Step 801, if respiratory standstill is first pressed the target setting tidal volume and is substituted ventilation once automatically:
After being step 7; When " flow processing module " can't detect changes in flow rate characteristic and the setting of the autonomous air-breathing beginning of sign according to the flow signal of flow transducer in the time of move at valve block last time the 10th second valve moves activation threshold value; This module will be sent signal immediately and give " respiratory standstill is disposed module automatically "; Send instruction immediately by it; The beginning valve moves to what B was ordered, promptly implements the once command ventilation, and its A point position and B point displacement all repeat the parameter of last time autonomous respiration mode of operation;
Step 802, stable if autonomous respiration rhythm recovers, continue the former target setting tidal volume ventilation of autonomous respiration mode:
Promptly after step 801, if next autonomous respiration began in 10 seconds, then repeating step 7;
Step 803, as occurring respiratory standstill once more, implement instruction with 80% of target tidal volume and substitute ventilation once:
If promptly after the step 801; When the valve that in the time of 10 seconds, can not detect changes in flow rate characteristic and the setting of the autonomous air-breathing beginning of sign once more according to the flow signal of flow transducer moves activation threshold value; Then module is sent signal once more immediately and is given " respiratory standstill is disposed module automatically "; Send the valve move immediately by it; But its B point displacement will be pressed 80% of target setting tidal volume and calculate modification again in proportion by " target tidal volume regulation and control module " according to actual tidal volume that obtains of step 801 and B point displacement;
Step 804, autonomous respiration rhythm recover stable, keep low tidal volume ventilation:
After promptly carrying out the once command ventilation by 80% of target setting tidal volume, if respiratory standstill no longer occurs, " respiratory standstill is disposed module automatically " will be sent instruction, target tidal volume setting value revised 80% and the repeating step 7 that becomes former setting value;
Step 805, as asphyxia still occurring, then attempt reducing tidal volume once more and set:
If after promptly tidal volume being reduced by 80%; Asphyxia still appears; Then dispose module automatically by respiratory standstill once more and implement the alternative command ventilation once, its Bx displacement is calculated and is revised by " target tidal volume regulation and control module " by 60% of former target setting tidal volume;
Step 806, as asphyxia still occurring, the mandatory ventilation mode of operation of changing one's profession:
If tidal volume still can not be eliminated respiratory standstill after reducing by 60%, then its reason of decidable is not physiological excessive power support, and is due to the central pathological changes, therefore can judge to be not suitable for adopting the autonomous respiration mode of operation." respiratory standstill is disposed module automatically " is the mandatory ventilation mode of operation with the respirator working mode transition immediately automatically; The baseline airway that originally set is pressed and the target tidal volume is set and keep; Its ventilatory frequency and Shi Bi then are set at 12 times/minute and 1: 2, to guarantee the ventilation safety of patient on respirator.After transferring mandatory ventilation to, also can add adjustment in addition to running parameter.
In sum; Under autonomous respiration mode; Central processing unit is through detecting the changes in flow rate that gets into patient airway; Come the controller of respirator resistance valve therein is sent instruction, make the ventilation action of machine synchronous, and maintain the target level of setting through the tidal volume that the auto-control to valve location makes respirator provide patient to patient's breath action maintenance; If judge in this pattern and breathe long-time the pause, can support autonomous respiration through the mode that reduces the target tidal volume, if still do not have the autonomous respiration sign, then change the mandatory ventilation pattern over to the patient is breathed support through the mode that reduces the target tidal volume.
More than disclosedly be merely several specific embodiment of the present invention, still, the present invention is not limited thereto, any those skilled in the art can think variation all should fall into protection scope of the present invention.

Claims (24)

1. respirator flow controlling method of air; It is characterized in that; The continuous flow of stability of flow is imported respirator system by source of the gas; And through the valve travel frequency of control airflow outlet end with apart from ventilation rhythm and the ventilation dynamics dynamically adjusted in the air flue, thereby realize breathing support to the patient, comprise following two kinds of mode of operations:
The mandatory ventilation mode of operation; Be used for unstable or use when providing the ventilation of specified level to support for the patient in patient respiratory impulsion; Under the mandatory ventilation mode of operation; The dynamic adjustment of the correction that central processing unit is ordered based on the base position A of said valve and the displacement B of valve, by-pass valve control moves at point-to-point transmission with frequency preset, thus the target tidal volume of in venting process, keeping setting provides mandatory ventilation support for the patient;
The autonomous respiration mode of operation; Confirm the beginning and the termination of patient's aspiratory action through dynamic pressure of air flue interface section and flow detection; The dynamic adjustment of the correction that the base position A of realization valve is ordered and the displacement B of valve; Central processing unit moves at point-to-point transmission with patient's autonomous respiration rhythm by-pass valve control according to said correction and adjustment result; Make the pressure in the air flue switch the respiratory movement of being obedient to the patient fully, in venting process, keep the target tidal volume of setting or when respiratory standstill appears in the patient, reduce the target tidal volume adaptively to keep the ventilation support of autonomous respiration.
2. respirator flow controlling method of air according to claim 1 is characterized in that, said mandatory ventilation mode of operation comprises the steps:
Mandatory ventilation frequency and breathing time ratio, target tidal volume and baseline airway are compressed into the line parameter setting and target tidal volume that is provided with and baseline airway are pressed the displacement key element that is converted into valve, and said valve displacement key element is base position A and displacement B;
Based on the displacement key element of said valve, central processing unit control starts first ventilation;
In first venting process; Instantaneous delivery and airway pressure to the air flue interface section detect; And based on the actual pressure that records with data on flows is analyzed and computing, draw the displacement B of A point position and adjusted valve after the calibration respectively and with its valve displacement key element as the initial ventilation of target tidal volume;
Central processing unit control starts the target tidal volume and initially ventilates; Be based in the first venting process A point position and adjusted valve displacement B after the calibration of confirming, and compare the said initial ventilation of execution with predefined said mandatory ventilation frequency and breathing time;
After initial the ventilation, continue the ventilation of target tidal volume and press the A point position and the displacement B that adjusts valve of recalibration valve periodically one by one, this dynamic calibration and adjustment are through change or the termination of whole ventilation supporting process until mandatory ventilation.
3. respirator flow controlling method of air according to claim 2 is characterized in that, the said analysis with computing according to the actual flow that records is specially:
The actual data on flows that records is by the flow curve data of reality entering air flue with because possibly exist minimum flow data two parts of revealing and causing to form; Show as the sawtooth waveforms on top and rectangular base two parts waveshape signal that possibly exist respectively; Through Filtering Processing to said waveshape signal; Keep said sawtooth signal and calculate actual tidal volume in view of the above, with the difference of said actual tidal volume and target tidal volume adjustment foundation as valve displacement B.
4. according to claim 2 or 3 described respirator flow controlling method of air, it is characterized in that said the analysis with computing according to the actual pressure data that records is specially:
With actual detected to pressure data and parameter setting up procedure in the baseline airway that is provided with compress into row relatively, if both errors≤± 3%, the valve A point position of then adopting the corresponding first ventilation of former basic airway pressure; If both errors>± 3% then calculates the valve A point position of upgrading according to the observed pressure and the valve A point position of first ventilation again in proportion.
5. respirator flow controlling method of air according to claim 2 is characterized in that, the change of said mandatory ventilation or termination specifically refer to:
The change of mandatory ventilation refers to change as required the parameter of in the parameter setting process, setting, and needs this moment to adjust accordingly by the parameter that resets;
The termination of mandatory ventilation refers to any time point cut-out work in venting process.
6. respirator flow controlling method of air according to claim 2 is characterized in that, the target tidal volume of said setting is 300 to 500 milliliters.
7. respirator flow controlling method of air according to claim 1 is characterized in that, said autonomous respiration mode of operation comprises the steps:
Target tidal volume, baseline airway pressure and inspiratory phase trigger sensitivity, expiratory phase converting sensitivity are carried out the parameter setting and target tidal volume that is provided with and baseline airway are pressed the displacement key element that is converted into valve, and said valve displacement key element is base position A and displacement B;
The detection of autonomous respiration inhalation flow and processing;
When the changes in flow rate characteristic of detected autonomous air-breathing beginning in the time of setting satisfies the said inspiratory phase trigger sensitivity threshold value of setting; Judge air-breathing beginning; According to the displacement key element of said valve, central processing unit control starts first ventilation, and valve begins to move to B from the A point; When detected flow drops to the expiratory phase converting sensitivity threshold value of setting, judge the beginning of exhaling, central processing unit instruction this moment valve returns the A point in moment;
In first venting process; Instantaneous delivery and airway pressure to the air flue interface section detect; And based on the actual pressure that records with data on flows is analyzed and computing, draw the displacement B of A point position and adjusted valve after the calibration respectively and with its valve displacement key element as the initial ventilation of target tidal volume;
When detecting changes in flow rate characteristic that autonomous respiration begins in the said setting-up time after first ventilation beginning once more and satisfy the said inspiratory phase trigger sensitivity threshold value of setting; Central processing unit control starts the target tidal volume and initially ventilates; Be based in the first venting process A point position and adjusted valve displacement B after the calibration of confirming, and carry out said target tidal volume with patient's self breath rhythm and initially ventilate;
After the initial ventilation; Continue the ventilation of target tidal volume and one by one by the A point position of recalibration valve and the displacement B of adjustment valve periodically, this dynamic calibration and adjusting through change or the termination of the ventilation supporting process of whole autonomous respiration until the autonomous respiration work process.
8. respirator flow controlling method of air according to claim 7; It is characterized in that; Respiratory standstill appears in the time in said setting first; Then implement the once command ventilation, when autonomous respiration rhythm recovers to stablize, continue the target tidal volume ventilation of the former setting of autonomous respiration mode by the valve displacement key element in the last time autonomous respiration mode of operation.
9. respirator flow controlling method of air according to claim 8; It is characterized in that; In the time in said setting, occur respiratory standstill once more, then implement the once command ventilation by the target tidal volume behind the downward modulation certain proportion, the valve displacement key element of this moment is calculated modification in proportion; When autonomous respiration rhythm recovers stablize, continue the target tidal volume of keeping after the downward modulation of autonomous respiration mode and ventilate.
10. respirator flow controlling method of air according to claim 9; It is characterized in that; Asphyxia in the time in said setting, still occurs, then further a certain proportion of target tidal volume of downward modulation is implemented the once command ventilation, and the valve displacement key element of this moment is still calculated in proportion and revised; If it is stable that autonomous respiration rhythm recovers, then continue the target tidal volume ventilation after reducing once more of keeping of autonomous respiration mode; If still can not eliminate asphyxia, judge that then asphyxia is due to the central pathological changes, this moment of enabled instruction immediately ventilation mode of operation is also pressed and target tidal volume parameter is carried out mandatory ventilation with the baseline airway of initial setting.
11. respirator flow controlling method of air according to claim 10; It is characterized in that; Judge that asphyxia is when being the mandatory ventilation mode of operation due to the central pathological changes and with the autonomous respiration working mode transition; The ventilatory frequency and the breathing time of mandatory ventilation pattern are set to 12 times/minute and 1: 2 than respectively, in order to guarantee ventilation safety.
12. respirator flow controlling method of air according to claim 7 is characterized in that, the time of said setting is 10 seconds.
13. respirator flow controlling method of air according to claim 7 is characterized in that, the range of choice of said inspiratory phase trigger sensitivity threshold value for for the 1-12 liter/minute.
14. respirator flow controlling method of air according to claim 13 is characterized in that, said inspiratory phase trigger sensitivity threshold value is specially 2 liters/minute.
15. respirator flow controlling method of air according to claim 7 is characterized in that, the range of choice of said expiratory phase converting sensitivity threshold value for for the 0-10 liter/minute.
16. respirator flow controlling method of air according to claim 15 is characterized in that, said expiratory phase converting sensitivity threshold value is specially 0 liter/minute.
17. respirator flow controlling method of air according to claim 7 is characterized in that, the said analysis with computing according to the actual flow that records is specially:
The actual data on flows that records is by the flow curve data of reality entering air flue with because possibly exist minimum flow data two parts of revealing and causing to form; Show as the sawtooth waveforms on top and rectangular base two parts waveshape signal that possibly exist respectively; Through Filtering Processing to said waveshape signal; Keep said sawtooth signal and calculate actual tidal volume in view of the above, with the difference of said actual tidal volume and target tidal volume adjustment foundation as valve displacement B.
18. respirator flow controlling method of air according to claim 7 is characterized in that, the said analysis with computing according to the actual pressure data that records is specially:
With actual detected to pressure data and parameter setting up procedure in the baseline airway that is provided with compress into row relatively, if both errors≤± 3%, the valve A point position of then adopting the corresponding first ventilation of former basic airway pressure; If both errors>± 3% then calculates the valve A point position of upgrading according to the observed pressure and the valve A point position of first ventilation again in proportion.
19. a respirator air flow controller is characterized in that, comprises source of the gas, central processing unit and resistance valve therein that is positioned at the air flue port of export and valve positioner that continuous flow can be provided, also comprises mandatory ventilation control chip and autonomous respiration control chip; Wherein,
Frequency and inspiratory to expiratory ratio that the mandatory ventilation control chip moves by the parameter by-pass valve control of setting; And based on the pressure that is positioned at the patient airway interface section, the real-time detected pressure of flow sensor, data on flows, in venting process dynamically the A of calibration valve point position and the adjustment valve displacement B; Said central processing unit moves at point-to-point transmission through said valve positioner by-pass valve control based on the result of each correction and adjustment and with frequency preset, thereby the target tidal volume of in venting process, keeping setting provides mandatory ventilation support for the patient;
The autonomous respiration control chip is through the setting of parameter and the real-time detected pressure of pressure, flow transducer, the data on flows that is positioned at the patient airway interface section; Confirm the beginning and the termination of patient's aspiratory action; And the dynamic adjustment of the displacement B of the base position A that realizes valve correction of ordering and valve; Central processing unit moves at point-to-point transmission with patient's autonomous respiration rhythm by-pass valve control according to said correction and adjustment result; Make the pressure in the air flue switch the respiratory movement of being obedient to the patient fully, in venting process, keep the target tidal volume of setting or when respiratory standstill appears in the patient, reduce the target tidal volume adaptively to keep the ventilation support of autonomous respiration.
20. respirator air flow controller according to claim 19 is characterized in that, said mandatory ventilation control chip comprises:
Baseline airway pressure-controlled module is used for pressing the actual pressure data that pressure transducer detects described in parameter and the venting process according to the baseline airway that is provided with, and dynamically calibrates the base position A point of valve;
Target tidal volume regulation and control module is used for the actual flow data according to the detection of flow transducer described in target tidal volume parameter that is provided with and the venting process, dynamically adjusts the displacement B of valve;
The time phase control module, be used for providing valve behind A point displacement B according to the mandatory ventilation frequency and the breathing time ratio that are provided with, moment is returned frequency and the time that A orders and controls again.
21. respirator air flow controller according to claim 20 is characterized in that, said target tidal volume regulation and control module specifically comprises:
The flow processing module is used for flow curve data that detected data on flows is resolved into the actual entering air flue that shows as sawtooth waveforms and the minimum flow data that show as rectangular base, and keeps said sawtooth waveforms through filtering;
The tidal volume computing module is used for receiving said sawtooth signal and calculates the actual tidal volume that air flue fills process.
22. respirator air flow controller according to claim 19 is characterized in that, said autonomous respiration control chip comprises:
Baseline airway pressure-controlled module is used for pressing the actual pressure data that pressure transducer detects described in parameter and the venting process according to the baseline airway that is provided with, and dynamically calibrates the base position A point of valve;
Target tidal volume regulation and control module is used for the actual flow data according to the detection of flow transducer described in target tidal volume parameter that is provided with and the venting process, dynamically adjusts the displacement B of valve;
The inspiratory phase modular converter; Be used to be provided with inspiratory phase trigger sensitivity threshold value; And when detecting the inhalation flow that gets into the patient airway interface section and the changes in flow rate characteristic of the air-breathing beginning of autonomous respiration and inspiratory phase trigger sensitivity threshold value that flow reaches said setting occur meeting; Judge air-breathing beginning and the signal of air-breathing beginning is sent to central processing unit, begin to move from the A point so that trigger valve;
The expiratory phase modular converter; Be used to be provided with expiratory phase converting sensitivity threshold value; And when detecting the inhalation flow that gets into the patient airway interface section and the changes in flow rate characteristic of the air-breathing end of autonomous respiration and expiratory phase converting sensitivity threshold value that flow reaches said setting occur meeting; The signal of the beginning and the beginning of will exhaling of judge exhaling is sent to central processing unit, so that triggering valve moment is returned the A point;
Respiratory standstill is disposed module automatically, is used for when respiratory standstill occurring first, carries out the once command ventilation by the target tidal volume of initial setting; When respiratory standstill appears in secondary, with carrying out the once command ventilation behind the target tidal volume downward modulation certain proportion; When respiratory standstill occurring for the third time, the target tidal volume is continued to carry out the once command ventilation behind the downward modulation certain proportion; Recover stable like autonomous respiration rhythm behind each mandatory ventilation, the target tidal volume of then keeping the setting of this time mandatory ventilation continues the ventilation of autonomous respiration mode of operation; As asphyxia still occurring after twice adjustment target tidal volume, judge that then asphyxia is due to the central pathological changes, the ventilation of enabled instruction immediately this moment mode of operation.
23. respirator air flow controller according to claim 22 is characterized in that, said target tidal volume regulation and control module specifically comprises:
The flow processing module is used for flow curve data that detected data on flows is resolved into the actual entering air flue that shows as sawtooth waveforms and the minimum flow data that show as rectangular base, and keeps said sawtooth waveforms through filtering; Also be used for judging whether respiratory standstill occurring and the signal of respiratory standstill being sent to respiratory standstill dispose module automatically in venting process;
The tidal volume computing module is used for receiving said sawtooth signal and calculates the actual tidal volume that air flue fills process.
24., it is characterized in that said resistance valve therein is an aperture formula resistance valves according to the described respirator air flow controller of claim 19 to 23.
CN201010517149.9A 2010-10-19 2010-10-19 Device for controlling airflow of respirator Active CN102451506B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201010517149.9A CN102451506B (en) 2010-10-19 2010-10-19 Device for controlling airflow of respirator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201010517149.9A CN102451506B (en) 2010-10-19 2010-10-19 Device for controlling airflow of respirator

Publications (2)

Publication Number Publication Date
CN102451506A true CN102451506A (en) 2012-05-16
CN102451506B CN102451506B (en) 2015-04-08

Family

ID=46035447

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201010517149.9A Active CN102451506B (en) 2010-10-19 2010-10-19 Device for controlling airflow of respirator

Country Status (1)

Country Link
CN (1) CN102451506B (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103340630A (en) * 2013-06-18 2013-10-09 东南大学 Identification device and identification method for breathe state of bi-level breathing machine
CN104707228A (en) * 2015-03-02 2015-06-17 深圳市科曼医疗设备有限公司 Transnasal high-flow-capacity oxygen therapy pressure monitoring system and method
CN104721927A (en) * 2015-02-12 2015-06-24 安庆市凌康机电产品设计有限公司 Animal spontaneous breathing device
CN105381526A (en) * 2015-12-08 2016-03-09 杭州电子科技大学 Intelligent outflow resistance switching simulation breathing apparatus
CN106730219A (en) * 2016-12-07 2017-05-31 杭州电子科技大学 Intelligent rehabilitation lung ventilator
CN104870039B (en) * 2012-12-18 2017-09-08 皇家飞利浦有限公司 Pressure of inspiration(Pi) control in volume mode ventilation
CN107519562A (en) * 2017-02-10 2017-12-29 钱家杰 Lung ventilator air-flow output control method
CN107859880A (en) * 2017-10-20 2018-03-30 上海航天能源股份有限公司 A kind of flow investigation analysis method that behavior is stolen for metering process after the pressure regulation of combustion gas elder generation
CN109464735A (en) * 2018-12-28 2019-03-15 乔璋晓 A kind of ventilator under the ventilating mode based on autonomous control
CN109718443A (en) * 2018-12-28 2019-05-07 北京谊安医疗系统股份有限公司 Breathing Suppotion process control method, device and Breathing Suppotion equipment

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090221926A1 (en) * 2006-05-12 2009-09-03 Magdy Younes Method and Device for Generating of a Signal that Reflects Respiratory Efforts in Patients on Ventilatory Support
CN201353353Y (en) * 2009-02-24 2009-12-02 江苏运达精密零部件有限公司 Invasive respirator
CN201862094U (en) * 2010-10-19 2011-06-15 袁含光 Air flow control device for breathing machine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090221926A1 (en) * 2006-05-12 2009-09-03 Magdy Younes Method and Device for Generating of a Signal that Reflects Respiratory Efforts in Patients on Ventilatory Support
CN201353353Y (en) * 2009-02-24 2009-12-02 江苏运达精密零部件有限公司 Invasive respirator
CN201862094U (en) * 2010-10-19 2011-06-15 袁含光 Air flow control device for breathing machine

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104870039B (en) * 2012-12-18 2017-09-08 皇家飞利浦有限公司 Pressure of inspiration(Pi) control in volume mode ventilation
US10293126B2 (en) 2012-12-18 2019-05-21 Koninklijke Philips N.V. Inspiratory pressure control in volume mode ventilation
CN103340630B (en) * 2013-06-18 2015-04-15 东南大学 Identification device and identification method for breathe state of bi-level breathing machine
CN103340630A (en) * 2013-06-18 2013-10-09 东南大学 Identification device and identification method for breathe state of bi-level breathing machine
CN104721927A (en) * 2015-02-12 2015-06-24 安庆市凌康机电产品设计有限公司 Animal spontaneous breathing device
CN104707228A (en) * 2015-03-02 2015-06-17 深圳市科曼医疗设备有限公司 Transnasal high-flow-capacity oxygen therapy pressure monitoring system and method
CN105381526A (en) * 2015-12-08 2016-03-09 杭州电子科技大学 Intelligent outflow resistance switching simulation breathing apparatus
CN106730219A (en) * 2016-12-07 2017-05-31 杭州电子科技大学 Intelligent rehabilitation lung ventilator
CN106730219B (en) * 2016-12-07 2018-12-07 杭州电子科技大学 Intelligent rehabilitation ventilator
CN107519562B (en) * 2017-02-10 2019-01-11 浙江大学 Ventilator air-flow output control system
CN107519562A (en) * 2017-02-10 2017-12-29 钱家杰 Lung ventilator air-flow output control method
CN107859880A (en) * 2017-10-20 2018-03-30 上海航天能源股份有限公司 A kind of flow investigation analysis method that behavior is stolen for metering process after the pressure regulation of combustion gas elder generation
CN109464735A (en) * 2018-12-28 2019-03-15 乔璋晓 A kind of ventilator under the ventilating mode based on autonomous control
CN109718443A (en) * 2018-12-28 2019-05-07 北京谊安医疗系统股份有限公司 Breathing Suppotion process control method, device and Breathing Suppotion equipment

Also Published As

Publication number Publication date
CN102451506B (en) 2015-04-08

Similar Documents

Publication Publication Date Title
CN102451506A (en) Method and device for controlling airflow of respirator
CN201862094U (en) Air flow control device for breathing machine
CN105828859B (en) Artificial respiration
US4340044A (en) Volume ventilator
US8397720B2 (en) Respirator and a process for operating a respirator
CN101479005A (en) System and method for adaptive high frequency flow interrupter control in a patient respiratory ventilator
US20140261424A1 (en) Methods and systems for phase shifted pressure ventilation
CN104203093B (en) For breathing system and method and the closed loop controller that energy is assessed in real time
JP6223340B2 (en) Method and apparatus for controlling a ventilator device
CN101730560A (en) Ventilator aerosol delivery
CN102114293B (en) Control system and method for implementing double horizontal pressures in air passage, breathing machine and anaesthetic machine
CN105980014B (en) Dual pressure sensor patient ventilation's equipment
CN103379934B (en) System and method for customizable automated control of fraction of inspired oxygen and/or positive end expiratory pressure to maintain oxygenation
CN104203320B (en) System and method for controlling insufflation pressure during inexsufflation
CN109152899A (en) Method and apparatus for giving patient ventilating
AU2013365956B2 (en) Inspiratory pressure control in volume mode ventilation cross-reference to related applications
CN102397609A (en) Ventilation method for ensuring volume and limiting pressure of anesthesia machine and breathing machine
CN103191503A (en) Pressure control device and pressure control method of respirator
CN105324144B (en) Synchronous airway pressure release ventilation
CN102114301B (en) PEEP (positive end expiratory pressure) valve and respirator with same
CN113260402A (en) Method and system for delivering oxygen to a patient
CN105079931A (en) Respirator
CN109731195A (en) Respiration parameter setting method, device and the Breathing Suppotion equipment of Breathing Suppotion equipment
CN107519562B (en) Ventilator air-flow output control system
CN1743021A (en) Artificial respirator of automatic regulating breather quantity/permin and method therefor

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant