CN102442926A - Method for continuously cyaniding sodium chloroacetate - Google Patents
Method for continuously cyaniding sodium chloroacetate Download PDFInfo
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- CN102442926A CN102442926A CN2010105033770A CN201010503377A CN102442926A CN 102442926 A CN102442926 A CN 102442926A CN 2010105033770 A CN2010105033770 A CN 2010105033770A CN 201010503377 A CN201010503377 A CN 201010503377A CN 102442926 A CN102442926 A CN 102442926A
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Abstract
The invention discloses a method for producing sodium chloroacetate by continuously cyaniding sodium chloroacetate and sodium cyanide. A production device comprises a material metering pump, a static mixer, and a tower reactor. The method is characterized by: pumping a sodium chloroacetate solution and a sodium cyanide solution having a prepared concentration into the static mixer for mixing, then sending the mixture to the tower reactor, carrying out cyaniding and moisture evaporation simultaneously in the tower reactor, using the heat realized by the reaction for vaporization of moisture, maintaining the stability of the reaction temperature, realizing the application of the reaction heat, and continuously carrying out the production process.
Description
Technical field
The invention belongs to the synthetic field of chemical, relate to the method for the synthetic cyanoacetic acid sodium of sodium chloroacetate cyaniding.
Technical background
Cyanoacetic acid sodium is a kind of broad-spectrum basic chemical industry raw material, is mainly used in productions such as malonic ester, cyanoacetate.Cyanoacetic acid sodium can be obtained by carbonylic preparation method and sodium chloroacetate Process for the cyanation.Oxo synthesis is to be raw material with the carbon monoxide, and under comparatively high temps and pressure, being that catalyzer is synthetic with the heavy metal obtains.This method is because catalyzer is expensive, and catalyst recovery is had any problem, and cost is higher; The sodium chloroacetate cyanide process is, and to be that raw material is synthetic with sodium chloroacetate and sodium cyanide obtain, and this method is because technology is simple, and raw material is easy to get, and production cost is lower, in industry, is widely adopted.But because the cyanogenation that sodium chloroacetate and sodium cyanide carry out is a quick thermopositive reaction, reaction process control difficulty; Often occur temperature runaway in the production, emit phenomenon such as pot, product color is pitch black, needs decolouring etc. further to handle; Influence product production and quality, restriction is produced and is carried out.The purpose of this invention is to provide a kind of mild condition, can guarantee sodium chloroacetate cyaniding method for quality.
Traditional technology sodium chloroacetate cyanogenation was in the reaction kettle of periodical operation, to carry out in the past; Concrete grammar is quantitatively to add sodium chloroacetate solution in the reaction kettle; Drip sodium cyanide solution slowly, process needs strict control drop rate, otherwise reaction can take place moment; Cause temperature runaway, emit phenomenons such as pot.Sodium cyanide is hypertoxic raw material, abnormality takes place very easily cause personal injury, produces serious consequence.The sodium chloroacetate cyanogenation is quick thermopositive reaction in addition, and reaction process need feed a large amount of water coolants reaction heat is removed, and needs consumed energy.
Summary of the invention
The present invention was with technology was different in the past, and its ultimate principle is to adopt reaction and evaporation coupled method, in tower reactor, accomplishes the N-process of sodium chloroacetate continuously; To react and the evaporation coupling, and utilize the sodium chloroacetate cyanogenation to emit heat, the moisture of vaporization reaction system is kept system temperature, has overcome the process temperature runaway, emits problems such as pot, the little Huang of neutralized product color and luster, and yield is high, and is effective.
The sodium chloroacetate of the present invention's statement and the technological process of the continuous Process for the cyanation of sodium cyanide comprise steps completion such as preparation of raw material, conveying, reaction; As shown in Figure 1; Technological process is summarized as follows: 1, in dosing vessel, sodium chloroacetate is disposed to finite concentration, massfraction is 10% to 100% (sodium chloroacetate); 2, sodium cyanide is configured to require concentration in dosing vessel; 3, two kinds of feed liquids are got into tower reactor with volume pump after flow measurement device is sent into mixer mixing, or directly after temperature measuring equipment is measured, directly send into the tower reactor reaction.Sodium chloroacetate liquid and sodium cyanide liquid can enter into the same position of tower reactor, also can get into the different positions of tower reactor.Feed liquid can be that one charging also can be divided into multiply charging (every kind of charging can be divided into the 1-16 thigh); Sodium chloroacetate solution and sodium cyanide solution thorough mixing in tower; React, custom-designed tower reactor can make reaction maintain best reaction environment for reaction process provides enough mass-and heat-transfer surfaces.The gaseous products that reaction process produces reclaims through the auxiliary facility of cat head, and the cyaniding product is reclaimed by the tower still, and the cyaniding process can also may be carried out batchwise continuously; The tower still obtains the little Huang of cyanoacetic acid sodium solution color and luster, steady quality, the processing of need not decolouring.
Mixing tank of the present invention is a tubular static mixer, and its structure is that the turning unit that many groups are reversed is set in pipeline, when fluid impels fluid to mix through being because runner rotates.
Tower reactor of the present invention is made up of segregation section, conversion zone, and column internals can be filler, also can be the tray column dish.
Application example
Sodium chloroacetate Process for the cyanation according to the invention has that production process is continuous, simple to operate, stable performance, and throughput is big, good product quality, high, the low power consumption and other advantages of yield.Its applicable cases can be explained by following instance:
Instance one
The cyanogenation of sodium chloroacetate and sodium cyanide:
In dosing vessel, sodium chloroacetate is formulated as 65% (massfraction) solution; Sodium cyanide is formulated as 30% (massfraction) solution in dosing vessel; Through volume pump two kinds of materials are sent into the flow measurement device metering; Get into mixer mixing then after behind the temperature measurement, send into custom-designed filler tower reactor, reaction process reaction heat is taken away temperature of reaction by water vapor and is maintained 90 ℃ all the time.Reaction process is steadily carried out fast.The water vapor that process generates circular batching after the auxiliary facility condensation uses.Obtain concentration and be 26% cyanoacetic acid sodium solution, the little Huang of color and luster, yield are 98.5%.
Instance two
The sodium chloroacetate of multiply charging and sodium cyanide cyanogenation:
In dosing vessel, sodium chloroacetate is formulated as 40% (massfraction) solution, sodium cyanide is formulated as 30% (massfraction) solution in dosing vessel, sodium chloroacetate solution is sent into the flow measurement device metering through volume pump; Then behind temperature measurement; Send into custom-designed filler tower reactor, sodium cyanide solution is divided into three strands, respectively by cat head; Get into the filler tower reactor in the tower and apart from tower still 1/3 position highly; Reaction process reaction heat discharges gentle than one charging, and the reaction heat that process produces discharges steadily, and reaction heat is taken away temperature of reaction by water vapor and maintained 88 ℃ all the time.Reaction process is steadily carried out fast.The water vapor that process generates circular batching after the auxiliary facility condensation uses.Obtain concentration and be 22% cyanoacetic acid sodium solution, the little Huang of color and luster, yield are 99%.
Claims (7)
1. the continuous cyanogenation of sodium chloroacetate and the sodium cyanide method of producing cyanoacetic acid sodium, its essential characteristic is that production equipment is made up of material metering conveying, static mixer, tower reactor; After sodium chloroacetate solution and the sodium cyanide solution that will prepare concentration with volume pump squeezed into static mixer and mixed; Send into tower reactor; Cyanogenation and moisture evaporation are carried out simultaneously in tower reactor, and the vaporization that heat is used for moisture is emitted in reaction, keep the stable of temperature of reaction; The utilization of realization response heat, production process is carried out continuously.
2. claim 1 tower reactor of explaining is made up of conversion zone and gas-liquid segregation section.
3. claim 1 static mixer of explaining is formed by adding the turning units that many groups reverse in the pipeline
4. the internals of claim 2 tower reactor of explaining can be filler, column plate or not be provided with column internals.
5. the technology that requires of right 1 does, sodium chloroacetate is at the head tank wiring solution-forming, gets into tower reactor or directly gets into tower reactor after delivering to mixer mixing after metering with pump, in tower reactor, carries out continuous cyanogenation, and product is drawn from the tower still.
6. the upper, middle and lower of the tower reactor that the sodium cyanide feed entrance point that sodium chloroacetate and cyaniding are used in the production technique of right 5 statement can be explained in right 2.
7. the feed entrance point of right 6 statements can have 1～16.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105033770A CN102442926A (en) | 2010-10-12 | 2010-10-12 | Method for continuously cyaniding sodium chloroacetate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105033770A CN102442926A (en) | 2010-10-12 | 2010-10-12 | Method for continuously cyaniding sodium chloroacetate |
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| CN102442926A true CN102442926A (en) | 2012-05-09 |
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| CN2010105033770A Pending CN102442926A (en) | 2010-10-12 | 2010-10-12 | Method for continuously cyaniding sodium chloroacetate |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105080432A (en) * | 2015-07-27 | 2015-11-25 | 河北科技大学 | Sodium chloroacetate continuous cyanation tower-type reactor and reaction method thereof |
| CN106366019A (en) * | 2016-08-31 | 2017-02-01 | 河北诚信有限责任公司 | Continuous cyaniding method in benzyl cyanide production |
| CN108299235A (en) * | 2017-10-30 | 2018-07-20 | 赵君 | A kind of continuous cyaniding device and its technique |
-
2010
- 2010-10-12 CN CN2010105033770A patent/CN102442926A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 《化学与粘合》 19831231 田霞 等 alpha-氰基丙烯酸酯系医用粘合剂的合成 42-51 , 第1期 * |
| 田霞 等: "α-氰基丙烯酸酯系医用粘合剂的合成", 《化学与粘合》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105080432A (en) * | 2015-07-27 | 2015-11-25 | 河北科技大学 | Sodium chloroacetate continuous cyanation tower-type reactor and reaction method thereof |
| CN106366019A (en) * | 2016-08-31 | 2017-02-01 | 河北诚信有限责任公司 | Continuous cyaniding method in benzyl cyanide production |
| CN108299235A (en) * | 2017-10-30 | 2018-07-20 | 赵君 | A kind of continuous cyaniding device and its technique |
| CN108299235B (en) * | 2017-10-30 | 2023-12-05 | 烟台国邦化工机械科技有限公司 | Continuous cyanidation device and process thereof |
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Application publication date: 20120509 |