CN102397623B - Implanted electrical nerve stimulation system with automatic alarm function and method - Google Patents
Implanted electrical nerve stimulation system with automatic alarm function and method Download PDFInfo
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- CN102397623B CN102397623B CN201010284672.1A CN201010284672A CN102397623B CN 102397623 B CN102397623 B CN 102397623B CN 201010284672 A CN201010284672 A CN 201010284672A CN 102397623 B CN102397623 B CN 102397623B
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- 238000000034 method Methods 0.000 title claims abstract description 12
- 230000007383 nerve stimulation Effects 0.000 title abstract 2
- 238000004891 communication Methods 0.000 claims abstract description 121
- 230000001537 neural effect Effects 0.000 claims description 29
- 230000002159 abnormal effect Effects 0.000 claims description 27
- 230000000638 stimulation Effects 0.000 claims description 26
- 210000005036 nerve Anatomy 0.000 claims description 10
- 210000004556 brain Anatomy 0.000 claims description 7
- 230000003902 lesion Effects 0.000 claims description 6
- 210000000278 spinal cord Anatomy 0.000 claims description 6
- 210000001186 vagus nerve Anatomy 0.000 claims description 6
- 230000001413 cellular effect Effects 0.000 claims description 5
- 230000001360 synchronised effect Effects 0.000 claims description 5
- 238000012790 confirmation Methods 0.000 claims description 2
- 230000006870 function Effects 0.000 description 8
- 230000015556 catabolic process Effects 0.000 description 6
- 239000007943 implant Substances 0.000 description 5
- 238000005265 energy consumption Methods 0.000 description 4
- 238000007689 inspection Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 230000000284 resting effect Effects 0.000 description 2
- 208000028389 Nerve injury Diseases 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000008764 nerve damage Effects 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
Abstract
The invention discloses an implanted electrical nerve stimulation system with automatic alarm function and a method, comprising a pulse generator with a first wireless communication module, and a patient controller, wherein the patient controller comprises a second wireless communication module, a micro-processing module and an alarm module, and the second wireless communication module is used for communicating with the pulse generator in a wireless manner. When the pulse generator detects a system fault or an exception, the pulse generator transmits a wakeup signal to automatically wake up the patient controller, the alarm information is transmitted to the patient controller through the first wireless communication module and the second wireless communication module, and the alarm module of the patient controller sends an alarm signal. Compared with the prior art, the invention utilizes the pulse generator and the existing wireless communication module of the patient controller, has no need to arrange an additional energy-consumable alarm device in the pulse generator, only needs software control to realize the automatic alarm after the pulse generator detects a system fault or an exception, timely informs the patient to troubleshoot the fault or exception, and consumes extremely low energy.
Description
Technical field
The present invention relates to implantable medical device field, especially there is the stimulation system of auto-alarm function.
Background technology
Nerve electric stimulation has important effect in maladjusted nervous system treatment and nerve injury rehabilitation.Implantable neural electrical stimulator, by such as nervus motorius, sensorineural specific nerve place implant electrode in human body, discharges high-frequency electrical stimulation, to stimulate specific nerve nucleus, thus makes function of human body return to the state of normal operation.
At present, implantable neural electrical stimulator mainly comprises and is used for the treatment of with the implanted lesions located in deep brain of the typical motion obstructive disease such as parkinson disease (DBS, be commonly called as brain pacemaker), implanted cortex stimulates (CNS), implanted spinal cord stimulation trial system (SCS), implanted Sacral nerve electrical stimulation system (SNS), implanted vagus nerve electric stimulation (VNS) etc.
Known implantable neural electrical stimulator mainly comprises pulse generator, electrode and outer control device usually.Wherein, pulse generator be connected with electrode thus the burst transmissions that pulse generator is produced to electrode, to carry out electricity irritation to nerve.Outer control device comprises doctor's program control instrument, patient controller.Wherein, patient controller is for being used for of being equipped with of patient, according to the device of the output parameter of pulse generator in oneself situation gauge tap or control agent, regulate in the range of accommodation that patient only can be arranged doctor usually voluntarily.Patient controller communicates with pulse generator by wireless communications mode, magnetic coil or other communication modes.
When pulse generator detects the system failure or be abnormal, usually need timely alert notice patient, patient goes to hospital to send for a doctor to fix a breakdown or get rid of voluntarily according to fault or abnormal conditions.There is no above-mentioned fault or abnormal auto-alarm function in pulse generator in the market, fixed a breakdown by doctor's program controller by doctor to hospital when can only wait Patient Detection exception or not feel well, therefore cannot handling failure in time.Especially, when patient carries out specific behavior as driven, certain risk is all existed to implant patient and other people.
Summary of the invention
For the deficiencies in the prior art, the technical problem to be solved in the present invention is to provide the lower implantable neural electrical stimulator with auto-alarm function of a kind of energy consumption, when pulse generator detects the system failure or is abnormal, can automatically wake patient controller up by wireless communication module and send alarm signal by patient controller, notify that patient fixes a breakdown or exception in time.
According to technical scheme provided by the present invention, a kind of implantable neural electrical stimulator with auto-alarm function, comprising: the pulse generator implanted, and described pulse generator comprises the first wireless communication module;
Be positioned at external patient controller, described patient controller comprises for the second wireless communication module, micro treatment module, the alarm module with pulse generator radio communication;
Send wake-up signal automatically to wake patient controller up enter wireless communication state when described pulse generator detects the system failure or be abnormal, warning message is sent to patient controller by the first wireless communication module and the second wireless communication module by described pulse generator, and the alarm module of described patient controller sends the appreciable alarm signal of patient.
Preferably, after described patient controller receives warning message, analyzed this warning message by the micro treatment module of described patient controller, as confirmed system jam or exception, then the microprocessor module of described patient controller sends alarm command to alarm module.
Preferably, the alarm module of described patient controller is one or more the combination in speaker, buzzer, photoelectric alarm or vibrating motor, when system jam or exception, the alarm signal that patient controller then can send the various ways such as sound, light, vibration notifies patient in time.
Preferably, described pulse generator and patient controller all have the state of listening to and full-speed communication state at least two states, when described pulse generator detects the system failure or abnormal backward patient controller sends wake-up signal, described patient controller is in the state of listening to; When the warning message that described patient controller received pulse generator transmits, described patient controller is in full-speed communication state.
Preferably, when described pulse generator detects the system failure or is abnormal, first wireless communication module of described pulse generator sends wake-up signal to the second wireless communication module of patient controller constantly or periodically, and the second wireless communication module of described patient controller is in all the time and continues the state of listening to.
Preferably, when described pulse generator detects the system failure or is abnormal, first wireless communication module timing of described pulse generator sends wake-up signal to the second wireless communication module of patient controller, and the second wireless communication module of described patient controller is synchronous with the first wireless communication module and be periodically in the state of listening to.
Preferably, described patient controller also comprises the 3rd communication module, and the warning message that the pulse generator received sends by described 3rd communication module is uploaded to the remote supervision system of attending doctor by cellular radio communication network or standard telephone network.
Preferably, after patient controller receives the warning message that pulse generator sends, described 3rd communication module is automatically uploaded this warning message or is uploaded this warning message after being confirmed by patient again to remote supervision system.
Preferably, described fault or abnormal signal are one or more the combination in battery exception, electrode exception, system reset, self test failure.
Preferably, described implantable neural electrical stimulator is the one in implanted lesions located in deep brain system, implanted cortex electric stimulation, implanted spinal cord stimulation trial system, implanted Sacral nerve electrical stimulation system or implanted vagus nerve electric stimulation.
Present invention also offers a kind of method of implantable neural electrical stimulator automatic alarm, the pulse generator of this system comprises the first wireless communication module, patient controller comprises for the second wireless communication module, micro treatment module, the alarm module with pulse generator radio communication, comprises the following steps:
A: described pulse generator carries out System self-test;
B: send wake-up signal when described pulse generator detects the system failure or be abnormal and automatically wake patient controller up and enter wireless communication state;
C: warning message is sent to patient controller by the first wireless communication module and the second wireless communication module by described pulse generator;
D: send the appreciable alarm signal of patient by the alarm module of described patient controller.
Preferably, the step of by the micro treatment module of described patient controller, this warning message being carried out to analysis confirmation is also had between step C and D, as confirmed system jam or exception, then the microprocessor module of described patient controller sends alarm command to alarm module.
Preferably, the alarm module of described patient controller is one or more the combination in speaker, buzzer, photoelectric alarm or vibrating motor.
Preferably, in stepb when described pulse generator detects the system failure or be abnormal, first wireless communication module of described pulse generator sends wake-up signal to the second wireless communication module of patient controller constantly or periodically, and the second wireless communication module of described patient controller is in all the time and continues the state of listening to.
Preferably, in stepb when described pulse generator detects the system failure or be abnormal, first wireless communication module timing of described pulse generator sends wake-up signal to the second wireless communication module of patient controller, and the second wireless communication module of described patient controller is synchronous with the first wireless communication module and be periodically in the state of listening to.
Preferably, described patient controller also comprises the 3rd communication module, and the warning message that the pulse generator received sends by described 3rd communication module is uploaded to the remote supervision system of attending doctor by cellular radio communication network or standard telephone network.
Preferably, after step D, described 3rd communication module is automatically uploaded this warning message or is uploaded this warning message after being confirmed by patient again to remote supervision system.
Preferably, the described system failure or abnormal signal are one or more the combination in battery exception, electrode exception, system reset, self test failure.
Preferably, described implantable neural electrical stimulator is the one in implanted lesions located in deep brain system, implanted cortex electric stimulation, implanted spinal cord stimulation trial system, implanted Sacral nerve electrical stimulation system or implanted vagus nerve electric stimulation.
Compared with prior art, advantage of the present invention is:
Present invention utilizes existing wireless communication module in pulse generator and patient controller, only need software control can realize when pulse generator detects the system failure or be abnormal, pulse generator automatically wakes patient controller up by wireless communication module and enters full-speed communication pattern, send the signal detected to patient controller, by patient controller, this signal is analyzed, if judge system jam or exception, be arranged on alarm module in patient controller and then automatically send alarm signal, can notify that patient fixes a breakdown or exception in time, without the need to increasing extra energy-dissipating device, energy consumption is less.
Accompanying drawing explanation
Accompanying drawing 1 is module principle figure of the present invention (the first embodiment);
Accompanying drawing 2 is module principle figure of the present invention (the second embodiment);
Accompanying drawing 3 is automatic alarm program flow chart of the present invention;
Wherein:
1, pulse generator; 101, the first wireless communication module; 102, the first power supply; 2, patient controller; 201, the second wireless communication module; 202, micro treatment module; 203, alarm module; 204, second source; 205, third communication module.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is further detailed explanation:
Embodiment one:
As shown in Figure 1, a kind of implantable neural electrical stimulator with auto-alarm function, comprising: the pulse generator 1 implanted, and described pulse generator 1 comprises the first wireless communication module 101 and the first power supply 102; And be positioned at external patient controller 2, described patient controller 2 comprise for the second wireless communication module 201 of pulse generator 1 radio communication, micro treatment module 202, alarm module 203 and second source 204.
Patient controller 2 described under normal operating conditions is communicated with the second wireless communication module 201 self-timing by the first wireless communication module 101 with pulse generator 1.Fixing because pulse generator 1 is its battery capacity in implantation, in order to the saves energy pulse generator most of the time is in resting state, pulse generator 1 communicates with certain frequency time opening communication window with patient controller 2, and that is pulse generator 1 and patient controller are in resting state simultaneously and are in the state of listening to simultaneously.Certainly, because patient controller 2 is not by the restriction of limited battery capacity, under normal operating conditions, also the state of listening to can be in all the time.
The pulse generator 1 that patient controller 2 and patient implant is One-to-one communication, namely the signal that pulse generator 1 sends can only be received by unique patient controller 2 of correspondence, and this unique patient controller 2 also can only control the pulse generator 1 in this patient body.Patient controller 2 is placed on the nearer place of distance patient usually, and be placed on the head of a bed as during rest, therefore wireless communication signals can reliably be listened to.
Figure 3 show the method for implantable neural electrical stimulator automatic alarm of the present invention, first pulse generator self-inspection, when described pulse generator 1 is judged the system failure or exception to be detected, then send wake-up signal automatically to wake patient controller 2 up and enter wireless communication state, then warning message is sent to patient controller 2 by the first wireless communication module 101 and the second wireless communication module 201 by pulse generator 1, by the micro treatment module 202 of described patient controller 2, this warning message is analyzed, as patient controller 2 judges that system there occurs fault or exception really, then the micro treatment module 202 of described patient controller 2 sends to alarm module 203 alarm signal that patient can perceive, timely notice implant patient goes to hospital to fix a breakdown and avoids contingent danger.As judged, system does not break down or extremely, then patient controller 2 does not send alarm signal.
After patient controller 2 receives warning message, the more serious and alarm signal determined, such as cell voltage is too low, and the micro treatment module 202 of patient controller 2 also can not be analyzed warning message and send alarm command directly to alarm module 203.
Compared with prior art, present invention utilizes existing wireless communication module in pulse generator and patient controller, without the need to increasing extra power consumption alarm device in pulse generator again, only need software control can realize automatic alarm after pulse generator detects the system failure or be abnormal, notify that patient fixes a breakdown or extremely, energy consumption is minimum in time.
The system failure of described pulse generator self-inspection or abnormal signal are one or more the combination in battery exception, electrode exception, system reset, self test failure.The alarm module 203 of patient controller 2 can be one or more the combination in speaker, buzzer, photoelectric alarm or vibrating motor, sends sound, light or vibration signal etc. can be notified patient in time by the signal automatic alarm of patient's perception when pulse generator self-inspection is broken down or be abnormal.
Pulse generator 1 and patient controller 2 all have the state of listening to and full-speed communication state at least two states, when sending wake-up signal to patient controller 2 after described pulse generator 1 detects the system failure or be abnormal, described pulse generator 1 and patient controller 2 are all in the state of listening to; When the warning message that described patient controller 2 received pulse generator transmits, described pulse generator 1 and patient controller 2 are all in full-speed communication state.
When described pulse generator 1 detects the system failure or be abnormal, can there is communication that warning message is passed to patient controller 2.The first communication mode is, the first wireless communication module 101 of pulse generator 1 continues to send wake-up signal to the second wireless communication module 201 of patient controller 2, and the second wireless communication module 201 of patient controller 2 is also in all the time and continues the state of listening to.This communication mode can ensure that warning message is passed to patient controller 2 in the very first time by pulse generator 1, but power consumption relatively.
The second communication mode is, when pulse generator 1 detects the system failure or is abnormal, first wireless communication module 101 of described pulse generator 1 regularly sends wake-up signal to the second wireless communication module 201 of patient controller 2, because patient controller 2 is not by the restriction of battery capacity, the second wireless communication module 201 of described patient controller 2 is in all the time and continues the state of listening to.
The third communication mode is, when described pulse generator detects the system failure or is abnormal, first wireless communication module 101 of described pulse generator 1 regularly sends wake-up signal to the second wireless communication module 201 of patient controller 2, second wireless communication module 201 of described patient controller 2 is synchronous with the first wireless communication module 101 and be periodically in the state of listening to, and this communication mode more saves energy consumption relative to above-mentioned other two kinds.
The implantable neural electrical stimulator with auto-alarm function of the present invention can be the one in implanted lesions located in deep brain system, implanted cortex electric stimulation, implanted spinal cord stimulation trial system, implanted Sacral nerve electrical stimulation system or implanted vagus nerve electric stimulation.
Embodiment two:
The pulse generator of the implantable neural electrical stimulator of present embodiment is identical with embodiment one, with embodiment one unlike, as shown in Figure 2, described patient controller 2 also add the 3rd communication module 205 on the basis of embodiment one, and the warning message that the pulse generator 1 received sends by described 3rd communication module 205 is uploaded to the remote supervision system of its attending doctor by cellular radio communication network or standard telephone network.Doctor can see these warning messages by the NMS of safety and process in time.Time necessary, doctor by the working condition of this system call interception patient device, can also open the treatment prescription for this implant patient, saves patient and to come and go time of hospital and expense.
After patient controller 2 receives the warning message that pulse generator 1 sends, described 3rd communication module 205 automatically can upload this warning message to remote supervision system, upload, to avoid maloperation after also can being confirmed this warning message by patient again.
The present invention also can have other various embodiments; when not deviating from the present invention's spirit and essence; those skilled in the art can make various corresponding change and distortion according to the present invention, but these change accordingly and are out of shape the scope that all should belong to claim of the present invention protection.
Claims (14)
1. there is an implantable neural electrical stimulator for auto-alarm function, it is characterized in that: comprising:
The pulse generator implanted, described pulse generator comprises the first wireless communication module;
Be positioned at external patient controller, described patient controller comprises for the second wireless communication module, micro treatment module, the alarm module with pulse generator radio communication;
Send wake-up signal automatically to wake patient controller up enter wireless communication state when described pulse generator detects the system failure or be abnormal, warning message is sent to patient controller by the first wireless communication module and the second wireless communication module by described pulse generator, the alarm module of described patient controller sends alarm signal, described pulse generator and patient controller all have the state of listening to and full-speed communication state at least two states, when sending wake-up signal to patient controller after described pulse generator detects the system failure or be abnormal, described patient controller is in the state of listening to, when the warning message that described patient controller received pulse generator transmits, described patient controller is in full-speed communication state, after described patient controller receives warning message, by the micro treatment module of described patient controller, this warning message is analyzed, as confirmed system jam or exception, then the microprocessor module of described patient controller sends alarm command to alarm module.
2. the implantable neural electrical stimulator with auto-alarm function according to claim 1, is characterized in that: the alarm module of described patient controller is one or more the combination in speaker, buzzer, photoelectric alarm or vibrating motor.
3. the implantable neural electrical stimulator with auto-alarm function according to claim 1, it is characterized in that: when described pulse generator detects the system failure or be abnormal, first wireless communication module of described pulse generator sends wake-up signal to the second wireless communication module of patient controller constantly or periodically, and the second wireless communication module of described patient controller is in all the time and continues the state of listening to.
4. the implantable neural electrical stimulator with auto-alarm function according to claim 1, it is characterized in that: when described pulse generator detects the system failure or be abnormal, first wireless communication module timing of described pulse generator sends wake-up signal to the second wireless communication module of patient controller, and the second wireless communication module of described patient controller is synchronous with the first wireless communication module and be periodically in the state of listening to.
5. the implantable neural electrical stimulator with auto-alarm function according to claim 1, it is characterized in that: described patient controller also comprises the 3rd communication module, the warning message that the pulse generator received sends by described 3rd communication module is uploaded to the remote supervision system of attending doctor by cellular radio communication network or standard telephone network.
6. the implantable neural electrical stimulator with auto-alarm function according to claim 5, it is characterized in that: after patient controller receives the warning message that pulse generator sends, described 3rd communication module is automatically uploaded this warning message or uploaded this warning message after being confirmed by patient again to remote supervision system.
7. the implantable neural electrical stimulator with auto-alarm function according to claim 1, is characterized in that: the described system failure or exception are one or more the combination in battery exception, electrode exception, system reset, self test failure.
8., according to the described implantable neural electrical stimulator with auto-alarm function arbitrary in claim 1 to 7, it is characterized in that: described implantable neural electrical stimulator is the one in implanted lesions located in deep brain system, implanted cortex electric stimulation, implanted spinal cord stimulation trial system, implanted Sacral nerve electrical stimulation system or implanted vagus nerve electric stimulation.
9. the method for an implantable neural electrical stimulator automatic alarm, it is characterized in that: the pulse generator of this system comprises the first wireless communication module, patient controller comprises for the second wireless communication module, micro treatment module, the alarm module with pulse generator radio communication, comprises the following steps:
A: described pulse generator carries out System self-test;
B: send wake-up signal when described pulse generator detects the system failure or be abnormal and automatically wake patient controller up and enter wireless communication state, when described pulse generator detects the system failure or is abnormal, first wireless communication module of described pulse generator sends wake-up signal to the second wireless communication module of patient controller constantly or periodically, and the second wireless communication module of described patient controller is in all the time and continues the state of listening to; Or the first wireless communication module timing of described pulse generator sends wake-up signal to the second wireless communication module of patient controller, the second wireless communication module of described patient controller is synchronous with the first wireless communication module and be periodically in the state of listening to;
C: warning message is sent to patient controller by the first wireless communication module and the second wireless communication module by described pulse generator;
D: carry out analysis confirmation to this warning message by the micro treatment module of described patient controller, as confirmed system jam or exception, enters step e;
E: send the appreciable alarm signal of patient by the alarm module of described patient controller.
10. the method for a kind of implantable neural electrical stimulator automatic alarm according to claim 9, is characterized in that: the alarm module of described patient controller is one or more the combination in speaker, buzzer, photoelectric alarm or vibrating motor.
The method of 11. a kind of implantable neural electrical stimulator automatic alarms according to claim 9, it is characterized in that: described patient controller also comprises the 3rd communication module, the warning message that the pulse generator received sends by described 3rd communication module is uploaded to the remote supervision system of attending doctor by cellular radio communication network or standard telephone network.
The method of 12. a kind of implantable neural electrical stimulator automatic alarms according to claim 11, it is characterized in that: after step D, described 3rd communication module is automatically uploaded this warning message or is uploaded this warning message after being confirmed by patient again to remote supervision system.
The method of 13. a kind of implantable neural electrical stimulator automatic alarms according to claim 9, is characterized in that: the described system failure or exception are one or more the combination in battery exception, electrode exception, system reset, self test failure.
14., according to the method for described a kind of implantable neural electrical stimulator automatic alarm arbitrary in claim 9 to 13, is characterized in that: described implantable neural electrical stimulator is the one in implanted lesions located in deep brain system, implanted cortex electric stimulation, implanted spinal cord stimulation trial system, implanted Sacral nerve electrical stimulation system or implanted vagus nerve electric stimulation.
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| CN201010284672.1A CN102397623B (en) | 2010-09-17 | 2010-09-17 | Implanted electrical nerve stimulation system with automatic alarm function and method |
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| CN201010284672.1A CN102397623B (en) | 2010-09-17 | 2010-09-17 | Implanted electrical nerve stimulation system with automatic alarm function and method |
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| CN103736206B (en) * | 2014-01-23 | 2015-11-25 | 北京品驰医疗设备有限公司 | A kind of implantable medical device with fail safe defencive function |
| CN106667437B (en) * | 2016-12-22 | 2023-05-26 | 北京品驰医疗设备有限公司 | System for predicting postoperative complications of implanted medical equipment |
| CN109064712A (en) * | 2018-09-07 | 2018-12-21 | 重庆医科大学 | A kind of monitoring warning device and method for early warning for the monitoring of the elderly's sleep heart rate |
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| US6564105B2 (en) * | 2000-01-21 | 2003-05-13 | Medtronic Minimed, Inc. | Method and apparatus for communicating between an ambulatory medical device and a control device via telemetry using randomized data |
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| US5891179A (en) * | 1997-11-20 | 1999-04-06 | Paceseter, Inc. | Method and apparatus for monitoring and displaying lead impedance in real-time for an implantable medical device |
| CN101385890A (en) * | 2008-10-17 | 2009-03-18 | 清华大学 | Patient controller for implantation medical instrument |
| CN101518668A (en) * | 2009-03-20 | 2009-09-02 | 武汉依瑞德医疗设备新技术有限公司 | Public machine case of intelligent defibrillation machine with safety device |
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