CN102362953A

CN102362953A - Chinese medicine for treating cytomegalovirus (CMV) pneumonia after renal transplantation

Info

Publication number: CN102362953A
Application number: CN201110337950XA
Authority: CN
Inventors: 刘红君; 季学君
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-10-21
Filing date: 2011-10-21
Publication date: 2012-02-29

Abstract

The invention discloses a Chinese medicine for treating cytomegalovirus (CMV) pneumonia after renal transplantation. The Chinese medicine is prepared from paris polyphylla, scutellaria baicalensis, phellodendron, honeysuckle, indigowoad leaf, indigowoad root, blackberrykiky rhizome, coptis chinensis, houttuynia cordata, oldenlandia diffusa, manyleaf paris rhizome, weeping forsythia, and liquorice; Chinese medicinal decoction is prepared by the conventional method which comprises the following steps of mixing medicines according to different properties of each Chinese medicine in a proportion, decocting, filtering, bottling and disinfecting; the medicine is the Chinese medicine; and according to the theory of traditional Chinese medicine formulas, the medicines are selected reasonably, and the Chinese medicine has large effects of clearing away heat and toxic materials. Through multiple-year clinical observation on patients, the medicine has an obvious curative effect and has obvious effects on patients suffering from CMV pneumonia after renal transplantation.

Description

A kind of Chinese medicine of treating CMV pneumonia after the renal transplantation

Technical field the invention belongs to technical field of Chinese medicines, relates to a kind of Chinese medicine of treating CMV pneumonia after the renal transplantation, is the Chinese patent medicine of feedstock production specifically with the Chinese herbal medicine.

Background technology CMV is the pathogenic source of disease microorganism of the main opportunistic of pulmonary infection behind the renal transplantation; The CMV pneumonia is one of the early stage main infection complication of renal transplantation recipients and cause of death; Western medicine antiviral treatments such as western medicine more former times commonly used Lip river is big, virazole, but the renal transplant recipients mortality rate is still higher after using these medicines.Laboratory inspection proof CMV pneumonia is a kind of viral infection; And the medicine therapeutic virus infection of traditional Chinese medical science heat-clearing and detoxifying herb has advantage; Therefore according to the traditional Chinese medical science rule of treatment, utilize that the unique advantage invention of heat-clearing and detoxifying herb is a kind of treats that the Chinese medicine of CMV pneumonia is very essential after the renal transplantation.

Summary of the invention the purpose of this invention is to provide a kind of Chinese medicine medicine with CMV pneumonia after the treatment renal transplantation of heat-clearing and detoxifying herb's medicine, to overcome the deficiency of prior art.

The objective of the invention is according to motherland's medical tradition medical science heat-clearing and toxic substances removing therapy to renal transplantation after pathogenetic understanding and the Therapeutic Principle thereof of CMV; With reference to modern pharmacological research; Therefrom filter out the natural Chinese medicinal herb of heat-clearing and toxic substances removing,, make the effect of its performance heat-clearing and toxic substances removing by the theory of Chinese medical science prescription.

Medicine of the present invention is the medicament of being processed by following raw materials by weight proportions

Rhizoma Paridis 30 gram Radix Scutellariaes 50 gram Cortex Phellodendris 75 gram Flos Loniceraes 40 gram Folium Isatidiss 75 gram Radix Isatidis 50 gram Rhizoma Belamcandae 60 gram Rhizoma Coptidis 75 gram Herba Houttuyniae 200 gram Herba Hedyotidis Diffusaes 150 gram Rhizoma Paridis 60 gram Fructus Forsythiaes 50 gram Radix Glycyrrhizaes 30 grams

Above-mentioned each component is processed Chinese medicine decoction by conventional method, accomplishes by following step successively:

1) decoct: above-mentioned all medicines are put into marmite, add the fiery decoction of the hydrology by 1: 2 of medicine total amount, boiled back 25 minutes, medicinal liquid is leached, 1: 1 by the medicine total amount adds slow fire boiling again, boils back 25 minutes, and medicinal liquid is leached;

2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrating mixing;

3) sterilization: the medicinal liquid bottle was put into the pressure cooker antibacterial 30 minutes, promptly get Chinese medicine medicine decoction of the present invention.

Medicine of the present invention is a Chinese medicine preparation, and is theoretical according to traditional Chinese medical science prescription, selects medicine reasonable, and heat-clearing toxin-expelling functions is powerful.Medicine of the present invention, warp is the clinical observation patient for many years, and is evident in efficacy, and CMV pneumonia patient after the treatment renal transplantation is had remarkable result.

Clinical drug of the present invention is taken the result and is shown, following advantage is arranged:

1, to select natural plant for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation, utilizes the comprehensive function treatment hand-foot-mouth disease of the medicine of respectively distinguishing the flavor of, and no chemicals is harmless to human non-toxic, has no side effect, and is safe and reliable.

2, slow fire of the present invention is fried in shallow oil water, and effective ingredient scatters and disappears few, and curative effect is high, and is cheap, taking convenience, no any discomfort disease.

3, medicine of the present invention is obvious to CMV pneumonia curative effect after treating renal transplantation.

4, clinical drug of the present invention is observed, the medicine of CMV pneumonia after other treatment treatment renal transplantation of instead.

For showing the therapeutic effect of CMV pneumonia after medicine of the present invention is to the treatment renal transplantation; The clinical observation of the present invention CMV pneumonia patient system after 1000 example treatment renal transplantations; And CMV pneumonia patient 100 examples are organized as a comparison after selecting the suitable treatment renal transplantation of medical history, the state of an illness, age and traditional therapy; Age 19-57 year, the course of disease 1 day-30 days.Experimental group: the conventional medicine of stopping using, take medicine of the present invention; Matched group: take conventional medicine, the observation period is 7 days, and check after 7 days does not have recurrence and is produce effects, and sb.'s illness took a favorable turn is evident as effectively, and it is not obvious invalid that sb.'s illness took a favorable turn.

Instructions of taking: one time 50 milliliters, 2 times on the one, warm water delivery service.The clinical experiment result sees table 1.

Table 1: take medicine of the present invention with take conventional medicine to the treatment renal transplantation after CMV pneumonia patient's observation of curative effect.

Group	Case load	Produce effects (routine number)	Effectively (routine number)	Effectively (routine number)	Total effective rate (%)
						Experimental group	2000	1300	700	0	100
Matched group	100	0	65	35	65.0
						T		2.48	5.62	2.10	3.75
P	＜0.05	＜0.05	＜0.05	＜0.05	＜0.05

Can find out from table 1, medicine of the present invention to 1000 example treatment renal transplantations after CMV pneumonia patient, obtain 680 examples that have of significant curative effect, account for 68.0%; That takes a turn for the better has 320 examples, accounts for 32.0%; Total effective rate reaches 100%.

The specific embodiment

Choose raw material by following proportioning:

1) decoct: above-mentioned all medicines are put into marmite, add hydrology fire by 1: 2 of medicine total amount and decoct, boiled back 20 minutes, medicinal liquid is leached, 1: 1 by the medicine total amount adds the fiery decoction of the hydrology again, boils back 20 minutes, and medicinal liquid is leached;

2) bottled: as to seal in the disinfectant bottle in advance with packing into behind twice filtrating mixing;

Claims

1. treat that the Chinese medicine of CMV pneumonia is characterized in that it is the decoction of being processed by the following weight proportion raw material after the renal transplantation: Rhizoma Paridis 30 gram Radix Scutellariaes 50 gram Cortex Phellodendris 75 gram Flos Loniceraes 40 gram Folium Isatidiss 75 gram Radix Isatidis 50 gram Rhizoma Belamcandae 60 gram Rhizoma Coptidis 75 gram Herba Houttuyniae 200 gram Herba Hedyotidis Diffusaes 150 gram Rhizoma Paridis 60 gram Fructus Forsythiaes 50 gram Radix Glycyrrhizaes 30 grams for one kind; Above-mentioned each component is processed Chinese medicine decoction by conventional method; 1), decoct accomplishes by following step successively:: above-mentioned all medicines are put into marmite, add the fiery decoction of the hydrology, boiled back 25 minutes by 1: 2 of medicine total amount; Medicinal liquid is leached; By the medicine total amount 1: 1 adds slow fire boiling again, boils back 25 minutes, and medicinal liquid is leached; 2), bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrating mixing; 3), sterilization: the medicinal liquid bottle was put into the pressure cooker antibacterial 30 minutes, get final product.