CN102334627A - Formula for pollen and queen bee larva solid beverage and preparation method thereof - Google Patents
Formula for pollen and queen bee larva solid beverage and preparation method thereof Download PDFInfo
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- CN102334627A CN102334627A CN2010102299344A CN201010229934A CN102334627A CN 102334627 A CN102334627 A CN 102334627A CN 2010102299344 A CN2010102299344 A CN 2010102299344A CN 201010229934 A CN201010229934 A CN 201010229934A CN 102334627 A CN102334627 A CN 102334627A
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Abstract
The invention relates to a formula for a pollen and queen bee larva solid beverage and a preparation method thereof. The solid beverage is developed based on the fact that wall-broken bee pollen and queen bee larva have pharmacological action on patients with hepatopathy. The invention discloses composition of the formula; that is, wall-broken bee pollen and queen bee larva freeze-dried powder are used as basic materials, and soybean lecithin, xylo-oligosaccharide, an extract of root of kudzu vine and the like are added. Components in the formula comprise, by weight, 50 to 90% of bee pollen, 5 to 10% of queen bee larva freeze-dried powder, 2 to 5% of soybean lecithin, 1 to 3% of xylo-oligosaccharide and 0.2 to 1% of the extract of root of kudzu vine, with the balance being accessories. The invention also discloses the preparation method for the solid beverage, and the preparation method is to select high-quality wall-broken bee pollen, queen bee larva freeze-dried powder, soybean lecithin, xylo-oligosaccharide, the extract of root of kudzu vine and accessories and to prepare the components into the solid beverage according to scientific formulation. The prepared solid beverage is rich in a plurality of proteins, amino acids, vitamins, mineral matters and biologically-active substances and is a good nutritional product for assisting in improving a variety of hepatopathy. Modern medical scientific research and clinical practices prove that pollen and queen bee larva have specific effects in assisting in treating a variety of hepatopathy.
Description
Technical field
The present invention relates to the prescription and the preparation method of a kind of pollen, queen bee nit freeze-dried powder solid beverage, is to have certain pharmacological action to develop according to melissa powder, queen bee nit to hepatopathy patients.
Background technology
In recent years, the nutrition problem of chronic hepatitis, cirrhosis, serious hepatitis comes into one's own to the effect and the influence of the whole course of disease day by day.Nutritionist Donaghy A that the west is famous and Ockanga J etc. discover that liver cirrhosis patient is many with tangible malnutrition, and the generation of this malnutrition and ascites, immunologic function reduction and hepatic encephalopathy is closely related.Scholars such as domestic Tang Zhen tongued bell also observe, and cirrhosis and chronic severe hepatitis, hepatic failure patient nearly all have tangible malnutrition.Tajika M thinks that especially a series of changes of protein metabolism and malnutrition are not only a kind of chronic wasting disease during cirrhosis, and can have a strong impact on patient's survival rate.Professors Meng Qinghua etc. are through discovering routine chronic heavy type virus hepatitis, hepatic failure patient's surplus 200 analysis on nutritional status and nutritional intervention; Slowly heavy hepatopathy people's malnutritive problem is very serious; Almost all there is this problem in each patient, needs early stage, comprehensive, rational nutritional support treatment, otherwise complication such as ascites, infection control difficulty; Hospital stays prolongs, and cost also can significantly increase.Diet nutrient intake and malnutritive index when refined clear grade has relatively been analyzed chronic severe hepatitis hepatic failure and liver cirrhosis patient people institute; The various diet nutrients of finding slow severe hepatopath are taken the photograph the people and are measured wretched insufficiency; The bad problem of energy-protein-vitamin is even more serious than liver cirrhosis patient; Nutritional intervention need be with combining with parenteral nutrition in meals and the intestines, and it is very necessary and urgent to replenish various nutrients in early days, all sidedly.
As the pollen of plant essence, its medical value just is familiar with by we ancestors and is utilized before more than 2000 years.China's pharmacology monograph Shennong's Herbal the earliest just has the record of pollen pini and typha pollen, says that these two kinds of pollen smells are sweet flat, nontoxic, can cure mainly abdominal distnetion heat evil gas, diuresis, and the hemostasis that disappears, clothes are made light of one's life by commiting suicide, beneficial gas, are prolonged life for a long time.Subsequently, people recognize gradually that through constantly groping the melissa powder is a kind of fabulous natural nutrient food and the natural health-care products that has potentiality.Thereby the research and development of melissa powder are consistent to have received great attention both domestic and external, and has obtained many progress.The results of study such as Hannelie Human in Ceng Zhi general, Cui Hongwei and the South Africa of China show; The melissa powder contains the multiple nutrients material, comprising 22 seed amino acids, 14 kinds of vitamin and 30 various trace elements and a large amount of active protease, nucleic acid, flavone compound and other active materials.The many forms with free amino acid of the protein that the melissa powder is rich in exist, and content surpasses milk, egg 5-7 times; Ascorbic content is higher than fresh fruit and vegetables, and the content of B family vitamin horn of plenty wherein is than high hundred times of honey.In numerous nutrient and healthcare products, the melissa powder contains the nutrient of A wide selection of colours and designs only, and the blend proportion of each nutritional labeling is also more reasonable.
The melissa powder has good nutrition and protective effect to liver cell exactly because so.Polish scholar Woicicki discovers; With the melissa powder is the water-soluble extractive and the fat-soluble extract of primary raw material; Hepatic injury to due to the factors such as carbon tetrachloride, ethionine, D-Gal and allyl alcohol all has the significant protection effect; The animal's liver cell repair is fast after using, functional rehabilitation is rapid, the substantial connection of prompting pollens nutrition and liver disease.The Yin Shuihong of Korea S etc. study confirmation; Pollen product can prevent that fat from accumulating in liver, hepatic injury has obvious suppression and improvement effect to the CCL4 induced mice, and it not only can obviously alleviate the damage of general liver cell device; Obviously reducing liver fat simultaneously becomes; To treating liver necrosis, suppress the formation of collagenous fibres under Disse chamber and the central vein, alleviate liver fibrosis.In view of the above, the author thinks, the product that the melissa powder is derived though can not replace medicine, has certain adjuvant treatment effect really, and safer, be more suitable for prolonged application.Lu builds new grade and takes the melissa powder per morning for mouse, not only can improve the activity of LDH in its cardiac muscle, the liver, but also can change its isozymogram.This change has the function that promotes and strengthen cardiac muscle, liver, has especially strengthened cardiac muscle and liver adaptability and the tolerance for hypoxemia or temporary transient anoxic.
Equally, our ancestors know edibility and the medical function of bee larva very early.Classify larva of bee (being honeybee) as the commodity tonifying recipes in the Sheng Nong's herbal classic, point out " honeybee flavor is sweet flat, and it is nontoxic to be slightly cold, and the main air head removes disease due to noxious agents produced by various parasites, in the thin wound of qi-restoratives, and pain in the chest and abdomen, clothes make us the good luster color for a long time, and are not old ".Though though the medicine of larva of bee food health care early has understanding, the research of its pharmacological action being carried out scientific system is inchoate in nearly decades.The nutritive value of queen bee nit and royal jelly is close, is the strong nourishing agent of a kind of human body, in health care, has got good effect.The queen bee nit freeze-dried powder has effectively been preserved the nutritional labeling of queen bee nit and more active material; Clinical practice shows, the grub freeze-drying powder all has excellent curative to hepatitis, blood platelet hemoglobin and leukopenia (containing the leucocyte that cancer therapy drug on probation, radiotherapy cause reduces).Through 10 tame hospital clinical applied statistics, disease 291 examples such as treatment hepatitis, total effective rate is 75%, the treatment leukopenia efficiently reaches 73.6%.Gondola scholar's research is found, injection and oral queen bee nit slurry can make the life-span of ascites carcinoma mouse prolong, and postponing appears in ascites, and cancer cell is grown has degenerative change, can alleviate the toxic action of chemotherapeutics to liver simultaneously.
In a word, melissa powder, queen bee nit except high nutritive value and health-care effect are arranged, to animal and the mankind still have significant raising immunity, strengthen physical, anti-ageing, protect pharmacological action and effect such as liver.And chronic liver disease and severe hepatopathy patients ubiquity nutritional deficiency or malnutrition, cell and HI and immunoloregulation function obviously reduce simultaneously.The reason of this kind immunologic hypofunction is numerous, and malnutrition is one of them important factor.Therefore, correct irrational nutrient imbalance or carry out the nutritional supplementation therapy,,, promote rehabilitation, be undoubtedly an important ring for the nutrition condition and the immunologic function of adjustment hepatopathy patients to improve the body nutrition condition.Present multinomial research proof melissa powder, queen bee nit show good nutritional supplementation effect to the malnutritive animal and the mankind; Can bring into play significant corrective action to immunologic hypofunction due to the malnutrition simultaneously, these results are that the chronic liver disease people that has nutritional deficiency and immunologic hypofunction concurrently can use the theoretical foundation that melissa powder and queen bee nit provide science.
Summary of the invention
Main purpose of the present invention provides a kind of prescription of novel pollen granules goods; Theoretical according to the traditional Chinese medicine allotment; Make full use of pollen, queen bee nit freeze-dried powder advantage separately, realize having complementary advantages, pollen and queen bee nit freeze-dried powder are organically combined.Make its not only comprehensive nutrition, be easily absorbed by the body.And mouthfeel is good, is easy to carry, and taking convenience has good medical care effect.
For achieving the above object, the present invention also provides the preparation method of this pollen, queen bee nit freeze-dried powder medicinal granules goods, and this method comprises the steps:
(1) buys high-quality broken pollen and queen bee nit freeze-dried powder and other auxiliary materials according to relevant criterion.
(2) various major ingredients, auxiliary material are pressed formula rate and mix, cross 80 mesh sieves.
(4) step (3) material is granulated.
(5) material of having granulated is carried out drying.
(6) whole grain.
(7) the intact material of whole grain is packed.
The present invention has passed through the grinding broken wall owing to select high-quality broken pollen and queen bee nit freeze-dried powder for use through science sterilization, removal impurity, pollen, makes the nutritional labeling in the product be easier to absorbed by human body.
It is the natural quality raw materials that most possibly satisfy the hepatopathy nutritional need at present that the present invention utilizes pollen and queen bee nit freeze-dried powder; These functional materials act synergistically on body; Give the suitable nutritional support of hepatopathy people and cooperate drug therapy; Can significantly reduce complication such as hepatopathy medication, shortening hospital stays, minimizing infection, when saving medical expense, the case fatality rate of some critical patients also is reduced.
The specific embodiment
Embodiment:
1, according to relevant criterion buying broken pollen, queen bee nit, soybean lecithin, xylo-oligosaccharide, kudzu root extract etc.
2, accurately take by weighing pollen 34.09kg, queen bee nit freeze-dried powder 3.41kg, soybean lecithin 1.70kg, xylo-oligosaccharide 1.17kg, kudzu root extract 0.20kg, auxiliary material 59.43kg joins V-Mixer.
3, open V-Mixer, mixed 45～60 minutes.
4, the material that mixes is crossed 80 mesh sieves.
5, granulate.
6, drying, baking temperature is advisable with 60 ℃～80 ℃.Water content is controlled in 5%.
7, whole grain sieves.
8, open quantitative package machine.Adjustment packing machine parameter to 60 bag/minute.
9, product is carried out sampling inspection, like qualified then directly coding, decals, the vanning warehouse-in is handled otherwise need to press defective work then.
Claims (10)
1. pollen, queen bee nit freeze-dried powder composition that hepatopathy is had auxiliary effect, said composition adds auxiliary material by one or more compositions in broken pollen (rape pollen, zasiokaurin etc.) and queen bee nit freeze-dried powder, soybean lecithin, xylo-oligosaccharide, the kudzu root extract and forms.
2. composition according to claim 1, melissa powder 50-90% wherein, the queen bee nit freeze-dried powder is 5-10%, lecithin 2-5%, xylo-oligosaccharide 1-3%, kudzu root extract 0.2-1%.
3. according to each described composition of claim 1-2, described composition is an oral formulations.
4. composition according to claim 3, described oral formulations is selected from pulvis, tablet, capsule, granule, pill, powder etc.; Be preferably pulvis, tablet, granule; Most preferably be granule.
5. composition according to claim 3, the consumption per day of said composition are every day 2-3 time, each 10-20 gram.
6. according to the said method for compositions of claim 1, with broken pollen and queen bee nit freeze-dried powder etc., mix according to certain weight ratio, the method processing according to required preparation promptly gets.
7. melissa powder, queen bee nit freeze-dried powder composition have the application in the nutritious supplementary pharmaceutical of hepatopathy and relevant disease effect thereof in preparation.
8. according to the application of claim 7, said product is applicable to hepatopath's daily health caring, especially is suitable for the nutritional supplementation of hepatopath's deficiency disease.
9. according to the application of claim 7, said product has has good nutritional supplementation effect to malnutritive crowd, can bring into play significant corrective action to immunologic hypofunction due to the malnutrition simultaneously; For the chronic liver disease people who has nutritional deficiency and immunologic hypofunction concurrently provides nutritional supplementation.
10. according to the application of claim 7, said product has the effect of regulating nervous system, regulating the gastrointestinal system function, promoting to digest or prevent the habitual constipation.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102299344A CN102334627A (en) | 2010-07-19 | 2010-07-19 | Formula for pollen and queen bee larva solid beverage and preparation method thereof |
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| CN2010102299344A CN102334627A (en) | 2010-07-19 | 2010-07-19 | Formula for pollen and queen bee larva solid beverage and preparation method thereof |
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| CN102334627A true CN102334627A (en) | 2012-02-01 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105815643A (en) * | 2015-01-07 | 2016-08-03 | 山东省蜂业协会 | Formula of compound honeycomb granules for protecting liver and preparation method thereof |
| CN106616719A (en) * | 2017-01-19 | 2017-05-10 | 合肥志诚蜂业有限责任公司 | Preparation method of queen bee larva chewable tablets |
Citations (6)
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| CN1087012A (en) * | 1993-04-17 | 1994-05-25 | 烟台三维应用技术研究所 | Medicinal preparation " Haiteshenlongkang " |
| CN1110160A (en) * | 1994-04-13 | 1995-10-18 | 廊坊市京龙饮料开发公司 | Nutrient health-care oral liquor containing bee larva nutritive composition |
| CN1459253A (en) * | 2002-05-22 | 2003-12-03 | 殷惠军 | Drink with functions of being beneficial to intelligence and taking care of liver and preparing process |
| CN1660417A (en) * | 2004-09-30 | 2005-08-31 | 周长信 | Formula of raw material pollen cream of nourishing face and preparing method |
| CN101480412A (en) * | 2008-01-12 | 2009-07-15 | 天水维尔康蜂业科技有限公司 | Honeybee four-treasure for treating prostatosis |
| CN101502306A (en) * | 2008-10-29 | 2009-08-12 | 中国农业科学院蜜蜂研究所 | Bee product composition and preparation method thereof |
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2010
- 2010-07-19 CN CN2010102299344A patent/CN102334627A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087012A (en) * | 1993-04-17 | 1994-05-25 | 烟台三维应用技术研究所 | Medicinal preparation " Haiteshenlongkang " |
| CN1110160A (en) * | 1994-04-13 | 1995-10-18 | 廊坊市京龙饮料开发公司 | Nutrient health-care oral liquor containing bee larva nutritive composition |
| CN1459253A (en) * | 2002-05-22 | 2003-12-03 | 殷惠军 | Drink with functions of being beneficial to intelligence and taking care of liver and preparing process |
| CN1660417A (en) * | 2004-09-30 | 2005-08-31 | 周长信 | Formula of raw material pollen cream of nourishing face and preparing method |
| CN101480412A (en) * | 2008-01-12 | 2009-07-15 | 天水维尔康蜂业科技有限公司 | Honeybee four-treasure for treating prostatosis |
| CN101502306A (en) * | 2008-10-29 | 2009-08-12 | 中国农业科学院蜜蜂研究所 | Bee product composition and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105815643A (en) * | 2015-01-07 | 2016-08-03 | 山东省蜂业协会 | Formula of compound honeycomb granules for protecting liver and preparation method thereof |
| CN105815643B (en) * | 2015-01-07 | 2021-02-26 | 济南杨氏医药有限公司 | Formula and preparation method of compound honeycomb granule electuary for protecting liver |
| CN106616719A (en) * | 2017-01-19 | 2017-05-10 | 合肥志诚蜂业有限责任公司 | Preparation method of queen bee larva chewable tablets |
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Application publication date: 20120201 |