CN102327460B - 一种治疗湿疹的药剂 - Google Patents
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Abstract
本发明涉及一种治疗湿疹的药剂，它是由下述重量配比的物质制成：金银花、麦冬、地黄、败酱草、陈皮、黄芩、千里光、青黛、知母、栀子、蛇床子、甘草、泽泻、乌梢蛇、赤芍和石菖蒲。本发明所述的治疗湿疹的药剂的全部成分都是天然材料，安全性较好，疗效明确，适于在临床上大规模推广。
Description
技术领域
本发明涉及医药领域，具体来说涉及一种治疗湿疹的药剂。
背景技术
湿疹(eczema)是一种常见的由多种内外因素引起的表皮及真皮浅层的炎症性皮肤病，一般认为与变态反应有一定关系。其临床表现具有对称性、渗出性、瘙痒性皮肤病、多形性和复发性等特点。湿疹是一种容易复发的皮肤病，治疗需要复发性专用药，如含有康洁净肤成分的药物，也是一种过敏性炎症性皮肤病以皮疹多样性，对称分布、剧烈瘙痒反复发作、易演变成慢性为特征。可发生于任何年龄任何部位，任何季节，但常在冬季复发或加剧有渗出倾向，慢性病程，易反复发作。。
发明内容
本发明的目的是提供一种治疗湿疹的药剂。
为了实现本发明的目的，本发明提供一种治疗湿疹的药剂，它是由下述重量配比的物质制成：金银花3-5份、麦冬1-3份、地黄1-3份、败酱草2-5份、陈皮0.1-0.5份、黄芩1-3份、千里光2-5份、青黛1-3份、知母3-5份、栀子3-5份、蛇床子1-3份、甘草5-8份、泽泻1-3份、乌梢蛇1-3份、赤芍3-5份和石菖蒲1-3份。
优选地，本发明所述的治疗湿疹的药剂是由下述重量配比的物质制成：金银花3份、麦冬2份、地黄3份、败酱草2份、陈皮0.3份、黄芩2份、千里光4份、青黛2份、知母4份、栀子3份、蛇床子2份、甘草6份、泽泻2份、乌梢蛇2份、赤芍4份和石菖蒲1份。
优选地，本发明的药剂可以为片剂、分散片、胶囊剂或软膏剂。可以采用本领域技术人员熟知的方法来进行药剂的制备。根据需要，可以加入各种药学上可接受的载体。所述的载体包括药学领域常规的稀释剂、赋形剂、填充剂、粘合剂、湿润剂、崩解剂、吸收促进剂、表面活性剂、吸附载体、润滑剂等。本发明的药剂在制备时，可选择的填充剂有：淀粉、糖粉、磷酸钙、糊精、微晶纤维素、乳糖、预胶化淀粉、甘露醇等；可选择的粘合剂有：羧甲基纤维素钠、PVP-K30、羟丙基纤维素、淀粉浆、甲基纤维素、乙基纤维素、羟丙基甲基纤维素、胶化淀粉等；可选择的崩解剂有：干淀粉、交联聚维酮、交联羧甲基纤维素钠、羧甲基淀粉钠、低取代羟丙基纤维素等；可选择的润滑剂有：硬脂酸镁、滑石粉、十二烷基硫酸钠、微粉硅胶等。
本发明所述的治疗湿疹的药剂的全部成分都是天然材料，安全性较好，疗效明确，适于在临床上大规模推广。
具体实施方式
下面通过实施例进一步说明本发明。应该理解的是，本发明的实施例是用于说明本发明而不是对本发明的限制。根据本发明的实质对本发明进行的简单改进都属于本发明要求保护的范围。除非另有说明，否则本发明中的百分数是重量百分数。
实施例本发明的软膏剂
称取金银花30克、麦冬20克、地黄30克、败酱草20克、陈皮3克、黄芩20克、千里光40克、青黛20克、知母40克、栀子30克、蛇床子20克、甘草60克、泽泻20克、乌梢蛇20克、赤芍40克和石菖蒲10克，粉碎，过80目筛，微粉化粉碎，过100目筛，混合均匀。向上述混匀的粉末中加入液体石蜡100克和凡士林200克，搅拌至呈均匀膏状，即得。
实验例
30例均符合《临床皮肤病学》湿疹诊断标准(赵辩.临床皮肤病学[M].第3版.南京：江苏科学技术出版社，2001.605.)。男19例，女11例；年龄27-74岁，平均47.6岁；病程3个月-10年，平均1.5年；前臂部湿疹6例，手背部湿疹4例，臀部湿疹者1例，大腿部湿疹者7例，小腿湿疹者9例，足背部湿疹3例。表现为皮损呈多形性，好发于面、手、足、小腿，可见红色斑或暗红色斑、丘疹、水疱、渗出、糜烂等，继发感染时可见脓疱、脓痂，瘙痒剧烈，伴心烦、口渴、大便秘结，舌质红苔黄，脉滑数。
使用实施例1中制备的软膏剂对于上述患者进行治疗，以均匀涂于患处为准，一日两次，以七天为一个疗程。
疗效标准
痊愈：皮疹全部消退，仅遗留色素沉着，瘙痒症状消失，随访1年未复发。显效：皮疹明显消退或大部分消退，瘙痒明显减轻，1年内偶有复发，但症状轻微，皮损较前减少。有效：皮疹部分消退，症状好转，有轻度瘙痒。无效：皮疹无消退或症状加重。
30例患者经治疗1个疗程后全部符合痊愈标准。
对于30例患者在治疗过程中进行跟踪观察，未发现明显的不良反应。
Claims (2)
1.一种治疗湿疹的软膏剂，其特征在于，它是由下述重量配比的物质制成：金银花3-5份、麦冬1-3份、地黄1-3份、败酱草2-5份、陈皮0.1-0.5份、黄芩1-3份、千里光2-5份、青黛1-3份、知母3-5份、栀子3-5份、蛇床子1-3份、甘草5-8份、泽泻1-3份、乌梢蛇1-3份、赤芍3-5份和石菖蒲1-3份。
2.根据权利要求1所述的治疗湿疹的软膏剂，其特征在于，它是由下述重量配比的物质制成：金银花3份、麦冬2份、地黄3份、败酱草2份、陈皮0.3份、黄芩2份、千里光4份、青黛2份、知母4份、栀子3份、蛇床子2份、甘草6份、泽泻2份、乌梢蛇2份、赤芍4份和石菖蒲1份。
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| CN102178804A (zh) * | 2011-04-28 | 2011-09-14 | 孔建 | 一种治疗肛周湿疹的中药组合物及其制备方法 |
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| CN1214261A (zh) * | 1998-10-21 | 1999-04-21 | 余际康 | 一种治疗皮肤病的口服药 |
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