CN102323361A - Post-column electrochemical derivatization apparatus for liquid chromatography - Google Patents
Post-column electrochemical derivatization apparatus for liquid chromatography Download PDFInfo
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- CN102323361A CN102323361A CN201110257965A CN201110257965A CN102323361A CN 102323361 A CN102323361 A CN 102323361A CN 201110257965 A CN201110257965 A CN 201110257965A CN 201110257965 A CN201110257965 A CN 201110257965A CN 102323361 A CN102323361 A CN 102323361A
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Abstract
The present invention relates to an electrochemical apparatus, which is provided for online generation of an electrochemical reaction, and is mainly adopted for post-column derivatization for a liquid chromatography system so as to achieve purposes of online electrochemical derivatization and online high-sensitivity detection of an analysis sample. The apparatus provided by the present invention is a post-column electrochemical derivatization apparatus for the liquid chromatography. The apparatus comprises an anode chamber, an anode, a cathode chamber, a cathode and power supply. A cation exchange membrane is sandwiched between the anode chamber and the cathode chamber. The cathode chamber is provided with a cathode chamber inlet and a cathode chamber outlet. The anode chamber is provided with an anode chamber inlet and an anode chamber outlet. The apparatus provided by the present invention has characteristics of simple structure, easy assembly, good reproducibility, fast analysis speed, and can continuously run for a long time. In addition, the apparatus provides high derivatization efficiency due to large electrode area.
Description
Technical field
The present invention relates to a kind of electrochemical appliance of online generation electrochemical reaction, be mainly used in the post-column derivation of liquid chromatographic system (chromatography of ions, high performance liquid chromatography), thereby the online galvanochemistry that realizes analytic sample is derived and online high-sensitivity detection.
Background technology
After some electroactive materials separated in the liquid chromatography system, through the galvanochemistry post-column derivation, the product after deriving had certain character (like fluorescence, ultraviolet etc.) and is detected by the relevant detection device.At present, the galvanochemistry derivatization reaction is accomplished by commercial electrochemical detector behind the post.This kind electrochemical detector electrode area is less, and the galvanochemistry efficient of deriving is not high, and costs an arm and a leg, and merely as the post-column derivation device, makes that the cost of whole analytical work is bigger.
Summary of the invention
The present invention provides a kind of online galvanochemistry deriving device, can be used in the liquid chromatographic system, have simple in structure, easy to assembly, favorable reproducibility, analysis speed is fast, but long-time continuous such as carries out at advantage; And it has the higher efficient of deriving because of having bigger electrode area.
Concrete technical scheme of the present invention is following:
The present invention is a galvanochemistry deriving device behind a kind of liquid-phase chromatographic column; Comprise anode chamber and anode, cathode chamber and negative electrode and power supply; Accompany cation-exchange membrane between anode chamber and the cathode chamber, cathode chamber is provided with cathode chamber inlet and cathode chamber outlet, and the anode chamber is provided with anode chamber's inlet and anode chamber's outlet;
Anode chamber of the present invention and cathode chamber can be the groove body type electrode chamber according to the shaped design of metal electrode, and the length and width size of anode and negative electrode is identical with electrode chamber, and anode and negative electrode can be the porous metal materials of platinum or titanium, and the aperture is about 50 μ m;
The checkout equipment of apparatus of the present invention analytical test sample is ion chromatograph or high performance liquid chromatograph.
Beneficial effect of the present invention is following:
The present invention is simple in structure, easy to assembly, but the fast long-time continuous of favorable reproducibility, analysis speed is carried out, and it has the higher efficient of deriving because of having bigger electrode area.
Description of drawings
Fig. 1 is the structural representation of galvanochemistry deriving device;
Be labeled as among Fig. 1:
1-anode chamber inlet; The outlet of 2-anode chamber; 3-cathode chamber inlet; The outlet of 4-cathode chamber; The 5-anode; The 6-negative electrode; The 7-cation-exchange membrane; 8,8 '-lead.
Specific embodiments
Further specify in the face of accompanying drawing provided by the present invention down:
Fig. 1 is the structural drawing of galvanochemistry deriving device: the galvanochemistry deriving device is provided with anode chamber's inlet 1 and anode chamber's outlet 2; Cathode chamber inlet 3 and cathode chamber outlet 4; Accompany cation-exchange membrane 7 between anode chamber and the cathode chamber; Anode chamber and cathode chamber all are equipped with metal electrode, anode 5 and negative electrode 6 be connected with power supply through plain conductor 8,8 '.Anode chamber and cathode chamber can be the groove body type electrode chamber according to the shaped design of metal electrode, and the size of anode 5 and negative electrode 6 is identical with electrode chamber, and anode 5 is the porous metal electrode with negative electrode 6.The volume of anode chamber and anode 5 is 46mm * 10mm * 1mm, and the volume of cathode chamber and negative electrode 6 is 46mm * 10mm * 1mm.Anode and cathode is by Ha Shi groove power source special (manufacturing of scientific instrument factory of Taishan City SAST) power supply, and voltage range is for being 0 ~ 15.5V.
During work; Component after chromatographic column is separated is by the 1 entering anode chamber that enters the mouth, the anode chamber of galvanochemistry deriving device; On anode 5, electrochemical oxidation reactions takes place, its oxidation product is transported to detecting device by anode chamber's outlet 2 and detects, and the tail washings that self-detector is discharged gets into cathode chamber through 3 circulations of cathode chamber inlet; In cathode chamber, serve as catholyte, drain into the waste liquid cylinder by cathode chamber outlet 4 again.
The present invention adopts the porous electrode of large surface area as electrode material, and porous electrode can have been simplified apparatus structure simultaneously as electrode and electrolyte passage, has higher oxidation efficiency.
Claims (4)
1. galvanochemistry deriving device behind the liquid-phase chromatographic column; It is characterized in that; Comprise anode chamber and anode, cathode chamber and negative electrode and power supply; Accompany cation-exchange membrane between described anode chamber and the cathode chamber, described cathode chamber is provided with cathode chamber inlet and cathode chamber outlet, and the anode chamber is provided with anode chamber's inlet and anode chamber's outlet.
2. according to galvanochemistry deriving device behind the said liquid-phase chromatographic column of claim 1, it is characterized in that described anode chamber and cathode chamber can be the groove body type electrode chamber according to the shaped design of metal electrode, the length and width size of anode and negative electrode is identical with electrode chamber.
3. according to galvanochemistry deriving device behind the said liquid-phase chromatographic column of claim 1, it is characterized in that described anode and negative electrode can be the porous metal materials of platinum or titanium.
4. galvanochemistry deriving device behind the liquid-phase chromatographic column according to claim 1 is characterized in that, the checkout equipment of analytical test sample is ion chromatograph or high performance liquid chromatograph.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110257965A CN102323361A (en) | 2011-09-02 | 2011-09-02 | Post-column electrochemical derivatization apparatus for liquid chromatography |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110257965A CN102323361A (en) | 2011-09-02 | 2011-09-02 | Post-column electrochemical derivatization apparatus for liquid chromatography |
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| CN102323361A true CN102323361A (en) | 2012-01-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201110257965A Pending CN102323361A (en) | 2011-09-02 | 2011-09-02 | Post-column electrochemical derivatization apparatus for liquid chromatography |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103698428A (en) * | 2013-12-18 | 2014-04-02 | 中国科学院过程工程研究所 | Vehicle-mounted portable liquid chromatographic instrument |
| CN104237449A (en) * | 2014-08-21 | 2014-12-24 | 浙江大学 | Barium carbonate electrolytic dissolution device |
| CN107870219A (en) * | 2016-09-26 | 2018-04-03 | 中国科学院大连化学物理研究所 | A kind of small chemical derivatization device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2852130Y (en) * | 2005-04-01 | 2006-12-27 | 侯文阁 | Multifunctional high-performance liquid chromatography post column derivation analyzer |
| CN102053130A (en) * | 2010-12-07 | 2011-05-11 | 浙江大学 | Ion chromatography-electrochemical derivative-fluorescence analysis system |
-
2011
- 2011-09-02 CN CN201110257965A patent/CN102323361A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2852130Y (en) * | 2005-04-01 | 2006-12-27 | 侯文阁 | Multifunctional high-performance liquid chromatography post column derivation analyzer |
| CN102053130A (en) * | 2010-12-07 | 2011-05-11 | 浙江大学 | Ion chromatography-electrochemical derivative-fluorescence analysis system |
Non-Patent Citations (1)
| Title |
|---|
| 吴述超 等，: "离子色谱-在线电化学柱后衍生-荧光检测叶酸类物质", 《第13届离子色谱学术报告会论文集》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103698428A (en) * | 2013-12-18 | 2014-04-02 | 中国科学院过程工程研究所 | Vehicle-mounted portable liquid chromatographic instrument |
| CN103698428B (en) * | 2013-12-18 | 2015-07-01 | 中国科学院过程工程研究所 | Vehicle-mounted portable liquid chromatographic instrument |
| CN104237449A (en) * | 2014-08-21 | 2014-12-24 | 浙江大学 | Barium carbonate electrolytic dissolution device |
| CN104237449B (en) * | 2014-08-21 | 2016-06-08 | 浙江大学 | Brium carbonate electrodissolution device |
| CN107870219A (en) * | 2016-09-26 | 2018-04-03 | 中国科学院大连化学物理研究所 | A kind of small chemical derivatization device |
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Application publication date: 20120118 |