CN102300600B - Microcatheter - Google Patents

Microcatheter Download PDF

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CN102300600B
CN102300600B CN 200980149936 CN200980149936A CN102300600B CN 102300600 B CN102300600 B CN 102300600B CN 200980149936 CN200980149936 CN 200980149936 CN 200980149936 A CN200980149936 A CN 200980149936A CN 102300600 B CN102300600 B CN 102300600B
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microcatheter
tube
segments
plurality
elongate
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CN 200980149936
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Chinese (zh)
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CN102300600A (en )
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J·古拉钦斯基
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微排放器公司
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Abstract

一种微导管,包括形成于内衬上的线圈。 A micro catheter comprising a coil formed on the liner. 该线圈由一系列外护套节段覆盖,所述节段的硬度相对于近端临近节段的硬度降低。 The coil is covered by a series of segments of the outer jacket, the hardness of the segments relative to the proximal segment adjacent the hardness decreases. 优选地,这些节段具有成角度的端部,以允许每个节段能被插入和结合进入其之前的节段。 Preferably, the segments having an angled end portion, to allow each segment to be inserted and incorporated into the segment preceding it. 外护套最终终止于具有最低硬度的节段的微导管远端。 The final outer sheath terminates at the distal end of the microcatheter segment having the lowest hardness.

Description

微导管 Microcatheter

[0001 ] 本申请要求2008年12月10日提交的、题为"Microcatheter"的、序列号为No . 61/ 121,525的美国临时申请的优先权,其整个内容合并在此。 [0001] This application claims the December 10, 2008, filed, entitled "Microcatheter", the serial number for the benefit of US Provisional Application No. 61 / 121,525, the entire contents of which are incorporated herein.

技术领域 FIELD

[0002] 本发明总体涉及医疗设备和制造该设备的方法。 [0002] The present invention generally relates to medical devices and methods of manufacturing the apparatus. 更特别地,本发明涉及微导管以及在执行介入医疗手术中使用的微导管的制造方法。 More particularly, the present invention relates to a method for producing a microcatheter and the microcatheter is used in performing an interventional medical procedure.

背景技术 Background technique

[0003] 微导管用于各种对发生在偏远的、高度弯折的脉管部位处的状况和疾病进行诊断和处置的医疗手术。 [0003] The microcatheter used for a variety of remote occurs, conditions and diseases at the site of vessel height bent diagnosis and management of medical procedures. 典型地,在第一位置处将微导管引入到患者脉管系统中,并随后通过患者的脉管向前,直到微导管的远端到达所期望的目标位置。 Typically, in a first position the microcatheter into the vascular system of a patient, and then forward through the patient's vasculature until the distal end of the microcatheter target position reaches a desired.

[0004] 微导管向前的过程通常包括靠近其远端施加力。 [0004] The process generally comprises the microcatheter forwardly applying a force near its distal end. 因此,当现有技术中的一些微导管更深地进入脉管系统中时,便很难适当地推动和机动操作微导管的远端。 Thus, when some of the prior art microcatheter deeper into the vasculature, it is difficult to appropriately push and maneuver the distal end of the microcatheter. 在这方面,期望一种具有更强的推动能力和追踪能力的微导管。 In this respect, a desire for a microcatheter have a stronger ability to promote and tracking capabilities. 推动能力通常理解为当最小化或不考虑弯折时将力从微导管的近端传送到微导管的远端的能力。 It is generally understood to promote the ability to minimize, or when the bending force is transmitted without regard to the microcatheter from the proximal end to the distal end of the microcatheter ability. 追踪能力通常理解为引导微导管通过弯折的脉管系统的能力。 Traceability is generally understood as the ability to guide the microcatheter through the vasculature of the bent.

[0005] 尽管现有技术中的微导管典型地能够在患者体内执行它们预定任务,但是仍然期望具有改进的导管性能,例如改进的追踪能力和推动能力。 [0005] Although the prior art microcatheter body typically capable of performing their intended task in a patient, it remains desirable to have improved catheter performance, such as improved capacity and ability to promote tracking.

发明内容 SUMMARY

[0006] 依照本发明的一个优选实施例,一种微导管包括形成于其内衬上的线圈。 [0006] According to a preferred embodiment of the present invention, a microcatheter comprising a coil formed thereon liner. 该线圈由一系列外护套节段或过渡节段覆盖,所述节段的硬度相对于近端临近节段的硬度降低。 The coil is covered by an outer jacket segment or series of segments transition, hardness of the segments relative to the proximal segment adjacent the hardness decreases. 优选地,这些节段具有成角度的端部,以使得每个节段能被插入和结合进入其之前的节段。 Preferably, the segments having an angled end portion, such that each segment can be inserted into and incorporated into the segment preceding it. 外护套最终终止于具有最低硬度的节段的微导管远端。 The final outer sheath terminates at the distal end of the microcatheter segment having the lowest hardness.

附图说明 BRIEF DESCRIPTION

[0007] 本发明实施例的这些以及其它的方面、特征和优点将能够从本发明实施例的下列说明中体现和阐明,参考附图,其中: [0007] These and other aspects, features and advantages of embodiments of the present invention will be capable of the following description of embodiments of the present invention is embodied and illustrated, with reference to the accompanying drawings, wherein:

[0008] 图IA图示了依照本发明优选实施例的微导管的侧横截面图; [0008] FIG IA illustrates a side cross-sectional view of a microcatheter according to a preferred embodiment of the present invention;

[0009] 图IB图示了从区域IB取得的图IA的微导管远端区域的放大图; [0009] FIG IB illustrates an enlarged view taken from the region of FIG. IA, IB microcatheter distal region;

[0010] 图IC图示了沿线IC取得的图IA的微导管的横截面图; [0010] FIG IC illustrates a cross-sectional view of the microcatheter of FIG. IA taken along line IC;

[0011] 图2A图示了图IA中具有弯曲远端区域的微导管; [0011] FIG IA 2A illustrates a distal end region having a curved microcatheter;

[0012] 图2B图示了从区域2B取得的微导管的远端区域,其中部分地移除了外护套; [0012] FIG 2B illustrates a microcatheter distal region taken from the area 2B, there is an outer sheath is partially removed;

[0013] 图3图示了依照本发明优选实施例的形成微导管的外护套的不同实例节段; [0013] FIG. 3 illustrates a different example of the outer sheath sections forming a microcatheter according to a preferred embodiment of the present invention;

[0014] 图4图示了依照本发明优选实施例的形成微导管的外护套的不同实例节段; [0014] FIG 4 illustrates an example of an outer sheath of the different sections forming a microcatheter according to a preferred embodiment of the present invention;

[0015] 图5A图示了具有对置的或相对定向的斜的有角度端部的两个外护套节段的侧视图; Obliquely angled end portions of the two side sections of the outer sheath [0015] FIG. 5A illustrates having opposed or oppositely directed;

[0016] 图5B图示了具有相似定向的斜的有角度端部的两个外护套节段的侧视图;以及 Obliquely angled end portions of the two side sections of the outer sheath [0016] FIG. 5B illustrates a similar orientation; and

[0017] 图5C图示了具有斜的有角度端部区域的护套节段的侧透视图。 [0017] FIG 5C illustrates a side perspective view of the housing segments angled end region having a diagonal.

具体实施方式 detailed description

[0018] 现将参考附图对本发明的具体实施例进行描述。 [0018] Reference is now made to the accompanying drawings of specific embodiments of the present invention will be described. 然而,本发明可以通过许多不同的形式来实施,并不应当解释为受限于在此描述的实施例;而是,提供这些实施例从而使得本公开变得详尽和完全,并将全面地向本领域普通技术人员表达本发明的范围。 However, the present invention may be embodied in many different forms and should not be construed as limited to the embodiments described herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully to Those of ordinary skill in the art convey the scope of the present invention. 在附图中所图释的实施例的详细描述中所使用的术语并不意在限制本发明。 Detailed description of embodiments of terms used in the drawings emoticon not intended to limit the present invention. 在附图中,相同的数字表不相同的部件。 In the drawings, like numerals in the table are not the same members.

[0019] 除非是有另外的限定,所有在此使用的术语(包括技术术语和科学术语)具有与本领域普通技术人员通常所理解的含义相同的含义。 [0019] Further, unless there is a defined, all terms (including technical and scientific terms) have the same meaning as those of ordinary skill in the art as commonly understood same meaning. 更进一步理解的是,术语(例如在通常使用的字典中定义的术语)应当解释为具有与它们在相关技术的上下文中一致的含义,不解释为理想化的或过于正式的理解,除非文中进行了特别限定。 Still further understood that the terms (such as those defined in commonly used dictionaries) should be interpreted as having a meaning that is consistent with their in the context of the relevant art, not be interpreted in an idealized or overly formal appreciated performed unless the context special limited.

[0020] 图IA图示了微导管100的优选实施例,微导管100包括连接到导管头部件102的长形的管部件101。 [0020] FIG IA illustrates a preferred embodiment of the microcatheter 100, the microcatheter 100 includes a head member connected to the conduit member 101 elongated tube 102. 管部件101的近端108连接到导管头102的远端,并还被应变消除部件106覆盖。 Proximal tube member 108 is connected to the distal end 101 of the catheter head 102 and cover 106 further strain relief member. 管部件101中至少一个中央管腔与导管头102内的通道相连通,从而形成导管通道104。 At least one tube member 101 and the central lumen within the catheter passage through the head 102 connected to the conduit passage 104 is formed. 在该示例的实施例中,引导线112定位穿过通道104,从管部件的远端110出来。 In this exemplary embodiment, the guide wire 112 positioned through passages 104, 110 from the distal end member.

[0021] 导管头102优选地采用DYMAX医用粘合剂或类似的粘合剂结合到近端部108。 [0021] The catheter head is preferably employed DYMAX 102 adhesive medical adhesive bonding or the like to the proximal portion 108. 应变消除部106可通过摩擦、粘合或类似的连接技术安装到导管头102上。 Strain relief portion 106 may be bonded by friction or a similar connection technique 102 is mounted to the catheter head.

[0022]如图IB和IC最佳所示,通道104由缠绕有线圈124的内衬114形成。 [0022] best shown in FIGS. IB and IC, the channel 104 of the coil 124 is wound around the inner liner 114 is formed. 线圈124覆盖有由多个不同的段形成的外护套116。 Coil 124 is covered with the outer sheath 116 is formed of a plurality of different segments. 外护套116的每个段的硬度优选地低于其近端的段的硬度。 Preferably the hardness of the outer jacket 116 of each segment is lower than the hardness of the proximal end section thereof. 在这方面,外护套116朝向远端110的挠性相对于近端108通常是增加的。 In this regard, the outer sheath 116 toward the flexible distal end 110 relative to the proximal 108 is generally increased.

[0023]如图2A所示,外护套优选地包括沿其一部分长度的亲水涂层。 As shown in [0023] Figure 2A, the outer sheath preferably comprises a hydrophilic coating along a portion of the length thereof. 优选地,该涂层距离微导管100的远末端大约100-120cm。 Preferably the distal tip, the microcatheter 100 coating from about 100-120cm.

[0024] 如图IB所示的横截面图以及图2B所示的视图,远端110包括结合在线圈层124和外护套116之间的两个不透射线的标记118和120。 [0024] The cross sectional view shown in FIG. IB and 2B view shown, distal end 110 includes two radiopaque marker binding between coil layer 124 and outer sheath 120 and 116,118. 在一个示例的布置中,标记120位于导管100 的远末端或靠近导管100的远末端,而标记118位于靠近标记带120大约3cm处。 In one example arrangement, the distal tip of the catheter marker 120 is located at or near the distal end 100 of catheter 100, 118 located close to the marker tag tape at about 3cm 120. 如图IB最佳所示,这些标记118和120能提供凸起的或升起的区域,这些区域能用于固定植入设备,例如支架。 Best shown in FIG. IB, the marks 118 and 120 to provide a raised or raised regions that can be used for fixation implant devices, such as stents.

[0025] 在一个示例中,从应变消除部106到远部110的远端测量,微导管100大约是150cm。 [0025] In one example, measurements from the strain relief portion 106 to the distal end of the distal portion 110, the microcatheter 100 is approximately 150cm. 中央管腔104具有大约0.0165至0.017英寸的内径。 About the central lumen 104 having an inner diameter of from 0.0165 to 0.017 inches. 远部110优选地包括大约40cm长(约1.9French)的区域。 Distal portion 110 preferably includes a region of about 40cm long (about 1.9French) a. 近部108优选地包括大约2.4French的区域。 Proximal portion 108 preferably includes a region of about 2.4French. 外护套116大约0.025英寸。 The outer jacket 116 of approximately 0.025 inches. [0026]内衬114优选地由聚四氟乙烯、PTFE或其他类似的材料构成,并具有在0.0005到0.007英寸范围内的壁厚。 [0026] The liner 114 is preferably made of polytetrafluoroethylene, the PTFE or other similar material, and having a wall thickness in the range of 0.0005 to .007 inches. 优选地,内衬114是"收缩的"或拉伸的以减小壁厚。 Preferably, the liner 114 is a "contracted" or stretched in order to reduce the wall thickness. 该拉伸还可选择性地定向材料的分子结构,从而赋予额外的性能特性。 The stretching may be selectively oriented molecular structure of the material, to impart additional performance characteristics. 例如,相对于类似的、具有相同厚度的不拉伸的材料,这种拉伸能增加爆裂强度和/或增加顺应性或柔软度。 For example, with respect to a similar, material having the same thickness is not stretched, this stretching can increase the burst strength and / or increasing the compliance or softness.

[0027]在这方面,微导管100的更小的部分用于内衬114,而其他部分的厚度可以增加而不增加微导管100的外径或减小微导管100的内径。 [0027] In this regard, a smaller portion of the microcatheter 100 for the liner 114, while the thickness of the other portion can be increased without increasing the outer diameter of the microcatheter 100, or reducing the internal diameter 100 of the microcatheter. 换句话说,拉伸内衬114允许内衬114与微导管其它部分(诸如外护套116)之间具有不同的厚度比。 In other words, having a different ratio of thickness between the liner 114 allow the liner to draw the microcatheter 114 and other portions (such as the outer sheath 116).

[0028] 例如,在内腔直径为大约0.0165到0.017英寸范围且外径为大约0.025英寸的10系统微导管中,在获得期望的性能结果时,外护套116与内衬114的厚度比大于约70%,更优选地是大约78 %。 [0028] For example, the inner lumen diameter of about 0.0165 to 0.017 inches and an outer diameter range of about 0.025 inches microcatheter system 10, the performance results obtained when a desired thickness of the outer sheath 116 is greater than the liner 114 about 70%, more preferably about 78%.

[0029]优选地,通过施加热和张力到内衬114,使得内衬114在组装之前得以拉伸。 [0029] Preferably, by applying heat and tension to the inner liner 114, 114 such that the liner is stretched prior to assembly. 例如, 可将大约250 °F到600 °F之间的温度施加到内衬114上同时以0.5到12英寸/分的速度施加50g到750g之间的张力。 For example, the temperature between about 250 ° F to 600 ° F is applied to the inner liner 114 while applying tension between 50g to 750g at from 0.5 to 12 inches / minute. 在另一示例中,内衬114可在室温下采用类似的或更强的力以及类似的或更快的速度进行拉伸。 In another example, the liner 114 can be similar or stronger force and similar or faster stretching at room temperature.

[0030] 在一个优选实施例中,内衬114可沿其长度具有均匀的厚度。 [0030] In a preferred embodiment, the liner 114 may have a uniform thickness along its length. 在另一优选实施例中,内衬114的厚度可朝向其近端增加,从而赋予额外的爆裂强度。 In another preferred embodiment, the thickness of the liner 114 may increase toward its proximal end so as to impart additional burst strength.

[0031] 线圈层124优选地由外径大约0.001英寸的丝状圆形导线形成。 [0031] The coil layer 124 is preferably formed of an outer diameter of about 0.001 inches filamentary round wire. 线圈124的节距优选在大约0.002到0.004英寸的范围内。 The pitch of the coil 124 is preferably in the range of from about .002 to 0.004 inches. 在一些微导管100的实施例中,线圈124还可形成为具有更紧的节距。 In some embodiments of the microcatheter 100, the coil 124 may be formed to have a tighter pitch.

[0032]在一个实例中,外护套116由多段具有各种硬度的聚醚嵌段酰胺,Pebax相互结合而形成(例如,热结合或胶粘合)。 [0032] In one example, the outer sheath 116 having various hardness by multi-polyether block amide, as Pebax bonded to each other to form a (e.g., thermal bonding, or gluing). 如图5C所图示的,第一护套段116A包括偏转的或成角度的端部116D。 As illustrated in FIG. 5C, a first jacket segment 116A includes a deflector or angled end portion 116D. 也就是说,节段端部116D不与沿节段116A地长度的的轴线116E垂直。 That is, the vertical axis of the end sections 116E 116D is not along the length of section 116A of. 优选地,这个角度可以在相对于轴线116E大约5-75度的范围内。 Preferably, this angle may be in the range of 5 to 75 degrees with respect to the axis 116E.

[0033]如图5A所示,节段116A成角度地结合在护套段116B中。 [0033] As shown in FIG. 5A, section 116A angularly incorporated in the jacket segment 116B. 成角度的切口端116D定向为使得其相对于成角度的切口端116C处于相对的旋转的位置。 116D angled cut end oriented such that an angle with respect to the cut end 116C at a position opposite to the rotation. 也就是说,端部116D和116C 的角度布置为形成三角形或梯形。 That is, the end portions 116D and 116C arranged at an angle to form triangular or trapezoidal.

[0034]优选地,节段116A和116B通过首先将成角度的切口端116D对着成角度的切口端116C放置来结合。 [0034] Preferably, the segments 116A and 116B become 116C by placing first cut end 116D against the angle of the angled cut end to bind. 随后,热收缩管放置到两个节段116A和116B上。 Subsequently, the heat-shrinkable tubing over the two sections 116A and 116B. 最后,施加热,使得热收缩管在直径上收缩,推动节段116A进入节段116B。 Finally, application of heat, such heat-shrinkable tube shrink in diameter, push section 116A into the segment 116B. 热收缩管的热和力都导致节段116A和116B 结合在一起。 Heat shrinkable tube and forces are lead sections 116A and 116B together. 最终,热收缩管可以从护套段移除。 Finally, the heat-shrinkable tube may be removed from the jacket segment.

[0035]如图5B所图示的,节段116A还可定向为使得成角度的切口端116D与成角度的端部116C处于同样的方向和方位。 [0035] illustrated in FIG. 5B, the segments 116A may also be oriented such that the angled end of the cutout 116D and the angled end portion 116C is in the same direction and orientation. 虽然两个节段都示出为具有成角度的端部,但是还可以设想只有一个节段可包括成角度的或偏转的端部。 Although two segments are shown as having an angled end portion, but it is also contemplated that only a portion of the end section may include an angled or deflected. 如图5A和5B的实例中所述的成角度的结合可减少弯折,通过保持挠性的同时提供额外轴向强度可能发生该弯折。 5A and 5B with examples of the angled bent can be reduced, to provide additional axial strength may occur while passing the bent flexible.

[0036] 优选地,外护套116具有7个节段,每个节段具有比近端邻近它的节段更低的硬度。 [0036] Preferably, the outer sheath 116 has seven segments, each segment having a proximal end than adjacent the lower segment of its hardness. 在这方面,外护套116朝向远端110变得更加柔韧。 In this regard, the outer sheath 116 becomes more flexible toward the distal end 110.

[0037] 看到图3,示例的外护套116示出为具有不同的节段。 [0037] See FIG. 3, an example of the outer sheath 116 is shown as having different sections. 节段150表示在近端108的节段,而节段162表示在远端110的节段。 Segment 150 in section showing the proximal end 108, and section 162 shows the distal end 110 of the segment. 在一个实例中,节段构成如下: In one example, the segments consisting of:

Figure CN102300600BD00061

Figure CN102300600BD00071

[0039] 看到图4,一个示例的外护套116示出为具有不同的节段。 [0039] See FIG. 4, an example of the outer sheath 116 is shown as having different sections. 节段164表示在近端108 的节段,而节段176表示在远端110的节段。 Segment 164 in section showing the proximal end 108, and section 176 shows the distal end 110 of the segment. 在一个实例中,节段构成如下: In one example, the segments consisting of:

Figure CN102300600BD00072

Luwi」 η」以认识到冲03义和Grilamid的甘;IStW晉俠物仕不观碘定匕知的,开η」和胜地米用。 Luwi "η" punch 03 to sense and recognize Grilamid Gan; IStW Shi-Jin Xia was not given dagger known concept iodine, open η 'and a spot meter. 还可以认识到内衬114和外护套116的壁厚可以改变,从而加强和提高一些特性,例如微导管100所期望的追踪能力、推动能力、内径和/或外径,以实施计划的手术。 Also it is appreciated that the wall thickness of the inner liner 114 and outer sheath 116 may be varied to enhance and increase a number of characteristics, such as a micro catheter 100 of the desired traceability, ability to promote, the inner and / or outer diameter, to plan surgery .

[0042] 本发明的一些实施例提供微导管100更强的末端成形能力和增强的末端形状保持。 Some embodiments [0042] The present invention provides a stronger end 100 forming the microcatheter tip, and enhanced shape retention. 关于末端成形能力,微导管100成形为直的(即,非预成形的)构型,其在使用之前被医生蒸汽成形为所期望的形状。 About formability end, the microcatheter 100 is shaped to a desired shape of a straight (i.e., non-preformed) configuration, which is shaped physician before using the steam. 导管100可以采用本领域众所周知的方式进行蒸汽成形。 Steam molding catheter 100 may be employed in the manner known in the art. 微导管100的末端形状保持大于55%。 The end shape of the micro catheter 100 remains greater than 55%. 在优选实施例中,末端形状保持为58%,而在另一优选实施例中,末έ而形状保持为67%。 In a preferred embodiment, the tip shape retention was 58%, and in another preferred embodiment, the end έ and shape retention of 67%.

[0043] 通过采用更薄的内衬114来提高末端形状保持,该内衬允许结合更厚壁的、可成形的外护套116。 [0043] to improve the shape of the end by using a thinner liner holder 114, which allows binding more thick lining, the outer sheath 116 may be formed. 末端形状保持还可以通过结合在内衬114和可成形的外护套116之间具有紧密的节距的线圈124来增强。 End shape of the holder may further have a tight pitch coil 124 between the liner 114 and the outer sheath 116 can be formed by enhanced binding. 紧密节距的线圈124布置为绕内衬114同心,使得微导管100的可成形的部分(即远端部110)不会严重受线圈124的拉直力影响。 Straightening force receiving portion (i.e., distal portion 110) close to the pitch of the coil 124 is arranged concentrically around the liner 114, so that the microcatheter 100 may be shaped coil 124 is not severely affected. 这与现有技术中的微导管形成对比,现有技术中的微导管采用辫状的或更长节距的线圈构型,以向微导管末端施加拉直力的方式在微导管可变形部分布置线或其它细丝。 This contrasts with the prior art microcatheter, the prior art microcatheter using braided or long pitch winding configuration to the deformed portion to the microcatheter tip of the microcatheter force pulling straight manner wire or other filament arrangement.

[0044] 虽然根据特定的实施例和应用来描述本发明,但是所属领域的普通技术人员在本教导下,在不脱离所要求保护的本发明的精神或超出所要求保护的本发明的范围的情况下,能得到另外的实施例和变形。 [0044] While the present invention is described in accordance with certain embodiments and applications, those of ordinary skill in the art at the present teachings, without departing from the spirit of the invention protection required, or exceeding the scope of the claimed invention as claimed in the case, additional embodiments can be obtained and modified. 从而,需要理解的是,在此以实例方式提供附图和说明,以便于对本发明的理解,而不应当认为是限制本发明的范围。 Thus, it is understood that the drawings and descriptions provided herein by way of example, in order to facilitate understanding of the invention and should not be considered as limiting the scope of the present invention.

Claims (15)

  1. 1. 一种微导管,包括: 具有多个节段的长形的管,每个节段的硬度低于近端邻近节段的硬度,邻近节段进一步包括相互处于相对的旋转位置的偏转的端部,其中所述偏转的端部通过热收缩管的热和力被推动进入和结合到邻近节段内; 线圈,位于所述长形的管的下方,并具有在0.002到0.004英寸范围内的节距;以及布置在所述线圈下方的内衬管,所述内衬管是拉伸的,以便可选择性地定向其材料的分子结构。 A microcatheter, comprising: an elongated tube having a plurality of segments, each segment is less than the hardness of proximal segment adjacent the hardness, further comprising adjacent segments in a mutually deflected relative rotational position of an end portion, wherein an end portion of the deflector is pushed into and bonded to the adjacent segment by heat and force of the heat-shrinkable tube; coil, positioned below said elongate tube, and having in the range of .002 to .004 inches pitch; and a liner disposed below the coil, the inner liner is stretched so as to selectively orient the molecular structure of the material.
  2. 2. 如权利要求1所述的微导管,还包括布置在所述长形的管上的亲水涂层,所述亲水涂层距离所述长形的管的远端100-120cm〇 2. The microcatheter according to claim 1, further comprising a hydrophilic coating disposed on said elongate tube, the distal end of the tube from the hydrophilic coating elongate 100-120cm〇
  3. 3. 如权利要求1所述的微导管,其中所述多个节段中的每一个相互成角度地结合。 The microcatheter according to claim 1, wherein in each of said plurality of segments combined to each other at an angle.
  4. 4. 如权利要求1所述的微导管,其中所述内衬管由PTFE构成,并具有在0.0005至0.007 英寸范围内的厚度。 4. The microcatheter according to claim 1, wherein said inner liner is made of PTFE, and has a thickness in the range of 0.0005 to 0.007 inches.
  5. 5. -种尺寸能够进入患者脉管系统的微导管,包括: 第一管节段,具有沿其长度的第一轴线,以及相对于所述第一轴线具有第一非垂直偏转角度的第一成角度的端部;以及第二管节段,具有沿其长度的第二轴线,以及相对于所述第二轴线具有第二非垂直偏转角度的第二成角度的端部; 其中所述第一非垂直偏转角度和所述第二非垂直偏转角度以相对于彼此相反定向的方式布置,以及其中,所述第一成角度的端部通过热收缩管的热和力被推动进入和结合到所述第二管节段内,形成长形的管;所述长形的管具有在所述长形的管的远端和近端附近开口的通道。 5. - microcatheter sizes can enter the patient's vasculature, comprising: a first pipe segment having a first axis along its length, and a first axis relative to the first having a first non-perpendicular angle of deflection angled end portion; and a second pipe section having a second axis along its length, and an end portion with respect to said second axis having a second angled deflection angle of a second non-vertical; wherein said first a non-vertical deflection angle and the second deflection angle is non-perpendicular orientation with respect to each other are arranged opposite, and wherein an end of the first angled portion is pushed into and coupled to the heat and force of the heat shrinkable tube said second tube section, forming an elongated tube; said elongate tube having a passage near the distal end of the elongated tube and a proximal opening.
  6. 6. 如权利要求5所述的微导管,其中所述长形的管还包括多个管节段,所述多个管节段至少部分地布置在所述多个管节段的至少另一个中;所述多个管节段的每一个包括至少一个成角度的端部。 At least another 6 microcatheter of claim 5, wherein the elongate tube further comprises a plurality of pipe segments, said plurality of tube segments disposed at least partially in said plurality of tube segments ; said plurality of tube segments each include an end portion of at least one angled.
  7. 7. 如权利要求5所述的微导管,其中所述长形的管还包括多个管节段,所述多个管节段的每一个由具有不同硬度的材料构成。 7. The microcatheter of claim 5, wherein the elongate tube further comprises a plurality of pipe sections, the plurality of tube sections each made of a material having a different hardness.
  8. 8. 如权利要求7所述的微导管,其中所述长形的管布置在具有0.002到0.004英寸的节距线圈上。 8. The microcatheter according to claim 7, wherein said elongate tube is disposed in an upper from 0.002 to 0.004 inches pitch coil.
  9. 9. 一种微导管,包括: 具有第一厚度的长形的管状护套,所述管状护套包括多个节段,所述多个节段具有相互处于相对的旋转位置的偏转成角度的端部;以及, 具有第二厚度的管状内衬,布置在所述长形的管状护套内; 其中,所述长形的管状护套具有0.025英寸的外径;以及, 其中,所述第一厚度和所述第二厚度之间的比大于70%; 其中所述偏转成角度的端部通过热收缩管的热和力被推动进入和结合到邻近节段内。 A microcatheter, comprising: an elongate tubular sheath having a first thickness, the tubular sheath comprises a plurality of segments, said plurality of segments having an angle to each other in a deflected relative rotational position of end; and a second inner tubular liner having a thickness, disposed within the elongate tubular sheath; wherein said elongate tubular sheath having an outer diameter of 0.025 inches; and, wherein, said first a ratio between the thickness and the second thickness is greater than 70%; wherein an end portion of the deflector angled to be forced into and bonded to the adjacent segment by heat and force of the heat shrinkable tube.
  10. 10. 如权利要求9所述的微导管,其中所述第一厚度和所述第二厚度之间的所述比是78% 〇 10. The microcatheter according to claim 9, wherein the ratio between the first thickness and the second thickness is a 78% square
  11. 11. 如权利要求9所述的微导管,还包括缠绕的线,布置在所述长形的管状护套和所述管状内衬之间。 11. The microcatheter according to claim 9, further comprising a wire wound, is disposed between the elongate tubular sheath and said tubular liner.
  12. 12. 如权利要求9所述的微导管,其中所述管状内衬包括已被拉伸的材料。 12. The microcatheter according to claim 9, wherein said tubular liner comprises a material that has been stretched.
  13. 13. 如权利要求9所述的微导管,其中所述管状内衬包括PTFE。 13. The microcatheter according to claim 9, wherein said tubular liner comprises PTFE.
  14. 14. 如权利要求9所述的微导管,其中所述长形的管状护套由多个成角度结合的护套节段构成。 14. The microcatheter according to claim 9, wherein said elongate tubular sheath bonded by a plurality of angled segments constituting the sheath.
  15. 15. 如权利要求9所述的微导管,其中所述管状内衬包括拉伸的PTFE材料。 15. The microcatheter according to claim 9, wherein the tubular lining material comprises PTFE stretched.
CN 200980149936 2008-12-10 2009-12-10 Microcatheter CN102300600B (en)

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US12152508 true 2008-12-10 2008-12-10
US61/121525 2008-12-10
PCT/US2009/067554 WO2010068793A1 (en) 2008-12-10 2009-12-10 Microcatheter

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6296631B2 (en) * 1998-04-28 2001-10-02 Sean L. Chow Flow directed catheter
US6503353B1 (en) * 1996-05-13 2003-01-07 Schneider (Usa) Inc. Method for making a catheter

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503353B1 (en) * 1996-05-13 2003-01-07 Schneider (Usa) Inc. Method for making a catheter
US6296631B2 (en) * 1998-04-28 2001-10-02 Sean L. Chow Flow directed catheter

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