CN102293902B - Black factice for treating snake bite - Google Patents
Black factice for treating snake bite Download PDFInfo
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- CN102293902B CN102293902B CN2011102453816A CN201110245381A CN102293902B CN 102293902 B CN102293902 B CN 102293902B CN 2011102453816 A CN2011102453816 A CN 2011102453816A CN 201110245381 A CN201110245381 A CN 201110245381A CN 102293902 B CN102293902 B CN 102293902B
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- China
- Prior art keywords
- rhizoma
- radix stephaniae
- caulis
- folium
- ampelopsis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 208000004078 Snake Bites Diseases 0.000 title abstract description 14
- 239000003814 drug Substances 0.000 claims abstract description 21
- 239000002994 raw material Substances 0.000 claims abstract description 5
- 235000009388 Parthenocissus quinquefolia Nutrition 0.000 claims description 10
- 239000002435 venom Substances 0.000 claims description 8
- 231100000611 venom Toxicity 0.000 claims description 8
- 210000001048 venom Anatomy 0.000 claims description 8
- 241000563984 Ampelopsis Species 0.000 claims description 5
- 241000219099 Parthenocissus quinquefolia Species 0.000 claims description 5
- 241000972155 Moschus Species 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 14
- 208000027418 Wounds and injury Diseases 0.000 abstract description 7
- 229940079593 drug Drugs 0.000 abstract description 7
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 235000008216 herbs Nutrition 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 239000000729 antidote Substances 0.000 description 4
- 230000017074 necrotic cell death Effects 0.000 description 4
- 239000002674 ointment Substances 0.000 description 4
- 244000153234 Hibiscus abelmoschus Species 0.000 description 3
- 206010031252 Osteomyelitis Diseases 0.000 description 3
- 208000006735 Periostitis Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 239000012467 final product Substances 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 241000270295 Serpentes Species 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- MINDHVHHQZYEEK-UHFFFAOYSA-N (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-(beta)-methyl-2H-pyran-2-crotonic acid ester with 9-hydroxynonanoic acid Natural products CC(O)C(C)C1OC1CC1C(O)C(O)C(CC(C)=CC(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-UHFFFAOYSA-N 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 206010028851 Necrosis Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000010513 Stupor Diseases 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 206010047115 Vasculitis Diseases 0.000 description 1
- -1 after 24 hours Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 239000008320 black ointment Substances 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229960003128 mupirocin Drugs 0.000 description 1
- 229930187697 mupirocin Natural products 0.000 description 1
- DDHVILIIHBIMQU-YJGQQKNPSA-L mupirocin calcium hydrate Chemical compound O.O.[Ca+2].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1.C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1 DDHVILIIHBIMQU-YJGQQKNPSA-L 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a new external drug for treating wound ulceration caused by a snake bite, and the drug is composed of the raw materials of 10 kinds of Chinese medicinal herbs. With a scientific and unique formula, the drug of black factice provided in the invention has substantial efficacy and curative effects.
Description
Technical field
The present invention relates to the suppurating sore of a kind for the treatment of take snakebite as the master, downright bad Chinese herbal medicine, specifically treat the medicine for external use of snakebite.
Background technology
China is located in temperate zone, subtropical zone, and especially southern climates is gentle, and the rainfall is plentiful, is fit to Serpentis class growth and reproduction.No matter be mountain area, coastal, many people are whenever arranged every year by venom.Snakebite originally is a kind of commonly encountered diseases, belongs to the emergency treatment emergency case.And it involves important system, particularly rural area and the outlying district shortages of medical services and medicines such as breathing, circulation, urinary system, nerve, if can not suit the remedy to the case or treat untimely, often causes the wounded dead or disable.At present, antidote for snake bites is no lack of minority, and insects, tubers, whole grass, oils and fats and mineral substance antidote for snake bites are arranged, and especially take snake medicinal liquor as many, it mainly is for oral administration, to prevent or to antidote against snake bite as main, the antidote for snake bites of holding concurrently health care.But for venom, after 24 hours, poison the intermediary and later stages, cause suppurating sore, necrosis, even injure the patient with severe symptoms of bone marrow, then effect is not too obvious." Li De wins the Serpentis sheet " reaches " Mupirocin Ointment ointment " on the market then has the treatment phase long, takes effect slow the unconspicuous defective of curative effect.
Summary of the invention
Purpose of the present invention is to provide a kind of and treats the venom intermediary and later stages for present existence 50% above patient is stung medium vessels and muscle by poisonous snake present situation, causes the external used medicine of suppurating sore, necrosis.Its for the wound surface that burn causes fester, necrosis, periostitis, osteomyelitis be also effective in cure.
Technical solution of the present invention is first heat-clearing and toxic substances removing, pain relieving, detumescence, putrefaction removing, the principle of rear convergence granulation promoting, according to motherland's medical science theories, drawn selectively the related disorders prescription elite of motherland's medicine, component invention people clinical experience, the Chinese herbal medicine that filters out significant curative effect is prescription scientifically, develop and specially control intermediary and later stages behind the venom and cause skin ulceration, suppurating sore, downright bad medicine for external use, it is treated targetedly for the venom disease, reaches desirable curative effect.Because the present invention is in manufacturing process, the colors such as crude drug " Herba Macleayae Cordatae " have played variation, are named as " black ointment " therefore be black.
(consumption is weight portion) that the present invention is made by following component:
Herba Macleayae Cordatae 9-11 Rhizoma Paridis 9-11 Rhizoma Dioscoreae Bulbiferae 9-11 Rhizoma Coptidis 2-4
Rhizoma Polygoni Cuspidati 9-11 Folium Rosae Laevigatae 5-7 Os Bovis seu Bubali 0.9-1.1
Exodermis Moschus 0.09-0.11 Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 7-9 Caulis seu folium ampelopsis brevipedunculatae (Caulis Ampelopsis Brevipedunculae) 9-11
Optimum weight of the present invention (part) proportioning is:
Herba Macleayae Cordatae 10 Rhizoma Paridis 10 Rhizoma Dioscoreae Bulbiferaes 10
Rhizoma Coptidis 3 Rhizoma Polygoni Cuspidati 10 Folium Rosae Laevigataes 6
Os Bovis seu Bubali 1 Exodermis Moschus 0.1 Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 8 Caulis seu folium ampelopsis brevipedunculatae (Caulis Ampelopsis Brevipedunculae)s 10
Making preparation method of the present invention by above-mentioned each component is:
1, the above-mentioned raw materials medicine is ground by proportioning, be processed into medicamental pulverata;
2, take the circumstances into consideration to spoon commercially available Adeps Serpentis, Oleum sesami furnishing ointment, get final product external.
For proving that this is the therapeutic effect of medicine, the applicant is disclosed in down patient's curative effect statistical result over more than 10 years, select selectively the clinical observation of 100 routine systems, and selection medical history, the state of an illness, age, snakebite patient's 72 examples that sex and former Therapeutic Method are suitable are matched group, from being in hospital and special outpatient clinic selection case, snakebite relate in, surgical patients is pressed the diagnostic criteria that WHO1980 formulates, and the diagnosis of the Chinese State Administration of Traditional Chinese Medicines in 2002 announcement, criterion of therapeutical effect, the adult snakebite patient who makes a definite diagnosis, be the object of observation on the basis of Drug therapy, male's 54 examples wherein, women's 46 examples; Venom suppurating sore patient 60 examples, suppurating sore, downright bad plyability patient 34 examples, the wound surface that burn causes 6 examples of festering, clinical symptoms is respectively: wound and part are burnt sample pain, severe pain, are bled; Blackout, purple, swelling are serious on every side, fever, and the severe patient vasculitis causes stupor etc., age 18-70 year, the course of disease 3 days-30 days.
Test group: application medicine of the present invention is processed in simple antiinflammatory, wrapping.
Matched group: use routinely common drug, injection and processing; Usage and test group are complementary, observation period 3-30.
Drug use method of the present invention: dark substitute of the present invention is applied in the wound affected part, begin one day three times, apply again with front clean affected part at every turn.A potion, alleviate or take a turn for the better after change one day secondary into, a 3-5 days course for the treatment of, get final product 2-3 the course for the treatment of.Test group is after 2-3 course of therapy, and is the longest 30 days, and the curative effect situation sees the following form:
Test curative effect information slip
As can be seen from the above table, use medicine of the present invention after, the various transference cures of patient do not need other auxiliary treatment, can subside a swelling, skin incrustation, wound healing, unique defective is easy scar.
The present invention is the clinical use of inventor more than 10 years, and medical effect is: amount to nearly 1000 examples for the treatment of patient, effective percentage 100%, cure rate 90%; The course for the treatment of 3-5, there are no the case of any toxicity, side effect and untoward reaction.Be characterized in: not only produce effect for snakebite intermediary and later stages patient, the wound surface that causes for burn festers, and deep burn and periostitis, osteomyelitis have significant curative effect.Such as following table:
Dark substitute curative effect table
The specific embodiment
Embodiment.Venom intermediary and later stages, suppurating sore, necrosis, and burn and scald causes that wound surface festers, periostitis, executing of osteomyelitis disease are controlled.
1, the composition of medicine and proportioning:
Herba Macleayae Cordatae
Rhizoma Paridis 10g Rhizoma Dioscoreae Bulbiferae 10g
Rhizoma Coptidis 3g Rhizoma Polygoni Cuspidati 10g Folium Rosae Laevigatae 6g
Os Bovis seu Bubali 1g Exodermis Moschus 0.1g Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 8g Caulis seu folium ampelopsis brevipedunculatae (Caulis Ampelopsis Brevipedunculae) 10g
2, preparation method and use:
The above-mentioned raw materials medicine is ground by proportioning, be processed into medicamental pulverata, take the circumstances into consideration to spoon commercially available Adeps Serpentis, Oleum sesami furnishing ointment, get final product external.
With this medicine for external use external application one day three times, 3-5 is a course for the treatment of, and take effect a general course for the treatment of, gradually recovery from illness, two recoveries from illness course for the treatment of of severe patient.
Claims (2)
1. a treatment causes suppurating sore, downright bad medicine for external use with venom, it is characterized in that Chinese medicine is comprised of the raw material of following weight proportioning:
Herba Macleayae Cordatae 9-11 Rhizoma Paridis 9-11 Rhizoma Dioscoreae Bulbiferae 9-11
Rhizoma Coptidis 2-4 Rhizoma Polygoni Cuspidati 9-11 Folium Rosae Laevigatae 5-7
Os Bovis seu Bubali 0.9-1.1 Exodermis Moschus 0.09-0.11 Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 7-9 Caulis seu folium ampelopsis brevipedunculatae (Caulis Ampelopsis Brevipedunculae) 9-11.
2. Chinese medicine according to claim 1, wherein each raw material weight proportioning is:
Herba Macleayae Cordatae 10 Rhizoma Paridis 10 Rhizoma Dioscoreae Bulbiferaes 10
Rhizoma Coptidis 3 Rhizoma Polygoni Cuspidati 10 Folium Rosae Laevigataes 6
Os Bovis seu Bubali 1 Exodermis Moschus 0.1 Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 8 Caulis seu folium ampelopsis brevipedunculatae (Caulis Ampelopsis Brevipedunculae)s 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102453816A CN102293902B (en) | 2011-08-20 | 2011-08-20 | Black factice for treating snake bite |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102453816A CN102293902B (en) | 2011-08-20 | 2011-08-20 | Black factice for treating snake bite |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102293902A CN102293902A (en) | 2011-12-28 |
| CN102293902B true CN102293902B (en) | 2013-03-06 |
Family
ID=45354734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011102453816A Expired - Fee Related CN102293902B (en) | 2011-08-20 | 2011-08-20 | Black factice for treating snake bite |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102293902B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810760A (en) * | 2010-04-30 | 2010-08-25 | 王祝民 | Black factice for treating snake bites |
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2011
- 2011-08-20 CN CN2011102453816A patent/CN102293902B/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN102293902A (en) | 2011-12-28 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130306 |