CN102253112A - Method for identifying substance by ion mobility spectrum - Google Patents
Method for identifying substance by ion mobility spectrum Download PDFInfo
- Publication number
- CN102253112A CN102253112A CN 201110175660 CN201110175660A CN102253112A CN 102253112 A CN102253112 A CN 102253112A CN 201110175660 CN201110175660 CN 201110175660 CN 201110175660 A CN201110175660 A CN 201110175660A CN 102253112 A CN102253112 A CN 102253112A
- Authority
- CN
- China
- Prior art keywords
- ion mobility
- ion
- relative
- mobility
- known substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 title claims abstract description 59
- 238000000034 method Methods 0.000 title claims abstract description 25
- 238000001228 spectrum Methods 0.000 title claims abstract description 12
- 238000013508 migration Methods 0.000 claims abstract description 43
- 230000005012 migration Effects 0.000 claims abstract description 43
- 238000012545 processing Methods 0.000 claims abstract description 12
- 239000012159 carrier gas Substances 0.000 claims abstract description 5
- 238000010438 heat treatment Methods 0.000 claims abstract description 4
- 230000037230 mobility Effects 0.000 claims description 116
- 238000001871 ion mobility spectroscopy Methods 0.000 claims description 49
- 239000000463 material Substances 0.000 claims description 33
- 239000007789 gas Substances 0.000 claims description 25
- 238000005070 sampling Methods 0.000 claims description 7
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 230000004069 differentiation Effects 0.000 claims description 6
- 230000015572 biosynthetic process Effects 0.000 claims description 5
- 238000002309 gasification Methods 0.000 claims description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 3
- 239000001301 oxygen Substances 0.000 claims description 3
- 229910052760 oxygen Inorganic materials 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 238000001514 detection method Methods 0.000 abstract description 3
- 150000002500 ions Chemical class 0.000 abstract 11
- 230000007547 defect Effects 0.000 abstract 1
- 230000005684 electric field Effects 0.000 description 7
- 230000007812 deficiency Effects 0.000 description 3
- 230000005596 ionic collisions Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 230000002950 deficient Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
Images
Landscapes
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
The invention provides a method for identifying substances by an ion mobility spectrum, which comprises the following steps: heating a substance to be detected, introducing sample molecules and a known substance A by a carrier gas into a migration tube to generate product ions, allowing the product ions to arrive a Faraday detector, allowing an electric signal to arrive a data processing unit through an amplifier and an A/D sampler orderly, calculating the ion mobility of the sample molecules and the known substance A to obtain the relative ion mobility of the sample molecules; comparing and differentiating the relative ion mobility of the sample molecules with data stored in a database, and displaying the identified results. The method of the invention allows the ion mobility to become a relative value relative to the ion mobility of the known substance A by obtaining the relative ion mobility and establishing a mobility spectrum database of the relative ion mobility, and the relative value is no longer restricted by detection and equipment; technical defects described in background technology are overcome, and the ion mobility spectrum database is provided with generality.
Description
Technical field
The present invention relates to the ion mobility spectrometry technical field, relate in particular to a kind of method of utilizing the ion mobility spectrometry recognition material.
Background technology
Each molecule, especially organic molecule all have its unique size, planform and mass-charge ratio.Therefore, molecule after the ionization is accelerated in electric field or electro-magnetic field, because of being subjected to backward transfer gas (buffer gas) collision, molecule after the ionization can be with a certain special speed at the uniform velocity straight line or circular motion, this speed can be measured, calculate corresponding mobility according to this measurable ratemeter, can determine the kind of this molecule according to this mobility.
A kind of principle of utilizing the ion migration to have the specific transfer rate that comes to this ion migration ratio spectrometer (IMS, Ion Mobility Spectrometer) detects the instrument of given sample molecule.In recent years, along with the increasing of food safety detection, anti-terrorism explosive substance detection demand, ion migration ratio spectrometer has obtained widespread use.
As shown in Figure 1, existing ion migration ratio spectrometer comprises: migration tube 11, amplifier 12, A/D sampling thief 13, data processing unit 14, display unit 15 and database 16.
Wherein, migration tube 11 is divided into ionization district 112 and migration area 114 two parts by ion gate 113, and ionization district 112 is also referred to as reaction chamber.Be provided with ion gun (not indicating among the figure), migration gas vent 116 and detected material sample molecule inlet 120 in the ionization district 112, be provided with migration gas access 118 and Faraday detector 115 in the migration area 114.
Detected material is heated, sample molecule after its gasification is brought into the ionization district 112 of migration tube 11 by carrier gas, under the ion gun effect a series of chemi-ionization reactions take place after, generate product ion, and the ion gate of opening through periodicity enters migration area 114, be provided with uniform electric field in the migration area 114, product ion obtains energy on the one hand and makes directional drift from electric field, neutrality migration gas molecule with reverse flow constantly collides and off-energy on the other hand, so formed the migration velocity along direction of an electric field on the macroscopic view.Because different product ion, its quality, electrically charged, the collision cross-section of institute and spatial configuration of molecules have nothing in common with each other, therefore, its migration velocities of product ion different in electric field is all different, its time that arrives on the Faraday detector 115 is also different, so we just can discern different materials by calculating the mobility of ion.
After Faraday detector 115 detects gas current, amplifier 12 through being connected with Faraday detector 115 is with small current signal (pA ~ nA) amplify, and export to A/D sampling thief 13, A/D sampling thief 13 is that digital signal is exported to data processing unit 14 again with analog signal conversion, data processing unit 14 calculates the ion mobility of sample molecule, and the ion mobility spectrometry of formation sample molecule, afterwards, compare with the known substance ion mobility spectrometry of preserving in the database 16, if consistent ion mobility spectrometry is arranged, then report to the police,, also inform by display unit 15 if there is not consistent ion mobility spectrometry by display unit 15.
The computing formula of described ion mobility K is (Anal. Chem. 2009,81 (14) for Valentine S.J., Clemmer D.J., 5876 ~ 5880):
K=
Wherein, Ω is the ion collision cross section, and z is the entrained charge number of ion, and k is the Boltzmann constant, T
EffBe ion temperature, P is the migration gas atmosphere, and T is the migration gas temperature, and N is the total molecular number of migration gas,
,
Be respectively mass of ion and migration gas molecule reduced mass, e is an electron charge.
As seen, each parameter of migration gas is for example moved gas atmosphere P, migration gas temperature T, ion collision cross section Ω and humidity and all ion mobility is exerted an influence.Here, described humidity is by influence migration gas molecule reduced mass
, ion collision cross section Ω and ion temperature T
EffAnd influence ion mobility K.
In actual measurement, general by measuring ion mobility spectrometry line time location T
iCalculate the mobility of i kind ion:
, wherein,
Be the mobility of i kind ion,
Be the speed of i kind ion, E is an electric field intensity, and L is a migration tube length.
At present, because the restriction of processing technology level, even if the migration tube of same manufacturer production, its structure also is difficult to reach in full accord, this makes the homogeneity of field uniformity and migration gas flowfield all can be affected, not only cause the loss of product ion, and make on same equipment, changing all can appear in the ion mobility that different time records same substance.
Therefore, though can carry out the identification of material by ion mobility spectrometry, but ion mobility and migration gas temperature, the migration gas humidity, migration gas flowfield homogeneity is closely related with field uniformity, can be subjected to the restriction of testing environment and equipment by the ion mobility spectrometry storehouse of ion mobility foundation, cause under varying environment and equipment, for same detected material, can draw different recognition results, therefore, there is certain technological deficiency in the method for utilizing ion mobility spectrometry to carry out material identification in the prior art, the ion mobility spectrometry database that uses this method to set up does not have versatility, can not discern material as sole criterion and demarcate.
Summary of the invention
For this reason, technical matters to be solved by this invention is: a kind of method of utilizing the ion mobility spectrometry recognition material is provided, makes the restriction of no longer examined environment of ion mobility spectrometry and equipment, the ion mobility spectrometry storehouse of using this method to set up has versatility.
So, the invention provides a kind of method of utilizing the ion mobility spectrometry recognition material, this method comprises:
The heating detected material, the sample molecule and the known substance A that contain in its gasification back detected material bring migration tube into by carrier gas in the lump, and generate product ion in migration tube;
The Faraday detector detects gas current and amplifies through amplifier, and via after the conversion of A/D sampling thief digital-to-analogue, exports to data processing unit;
Data processing unit calculates the ion mobility of described sample molecule and the ion mobility of known substance A, and obtains the relative ion mobility of sample molecule according to described two ion mobilities;
The ion relative mobility of the known substance preserved in the ion relative mobility of described sample molecule and the database is compared differentiation, and the demonstration recognition result, the ion relative mobility of the known substance of preserving in the described database is the relative ion mobility database by the relative ion mobility formation of the ion mobility acquisition of the ion mobility of known substance and known substance A.
The relative ion mobility that transport factor obtains, comprising: said method also comprises: after the relative ion mobility of described acquisition sample molecule, formed the ion relative mobility spectrum of described sample molecule by this relative ion mobility;
The ion relative mobility spectrum of the known substance preserved in the ion relative mobility of described sample molecule spectrum and the database is compared differentiation, and the demonstration recognition result, the ion relative mobility spectrum of the known substance of preserving in the described database is the relative ion mobility spectrometry database by the relative ion mobility formation of the ion mobility acquisition of the ion mobility of known substance and known substance A.
Wherein, described according to described sample molecule ion mobility and known substance A from
According to
Perhaps
Obtain relative ion mobility, wherein,
Be relative ion mobility,
Be the ion mobility of the sample molecule that contains in the detected material,
Ion mobility for known substance A.
Wherein, described known substance A can be water vapour or oxygen.
Wherein, described demonstration recognition result comprises:
If consistent ion mobility spectrometry is arranged, then show this material title, if there is not consistent ion mobility spectrometry, also shows and do not contain any known substance.
The method of utilizing the ion mobility spectrometry recognition material of the present invention, by obtaining relative ion mobility and setting up relative ion mobility spectrometry database, make ion mobility become a relative value with respect to the ion mobility of known substance A, the restriction of no longer examined environment of this relative value and equipment, overcome the technological deficiency described in the background technology effectively, made the ion mobility spectrometry database have versatility.
Description of drawings
Fig. 1 is a prior art intermediate ion mobility spectrometer structural representation;
Fig. 2 is the process flow diagram that utilizes ion mobility spectrometry recognition material method of the present invention.
Embodiment
Below, describe the present invention in conjunction with the accompanying drawings.
As shown in Figure 2, present embodiment provides a kind of method of utilizing the ion mobility spectrometry recognition material, and this method comprises:
Step 22, the sample molecule and the known substance A that contain after the detected material gasification bring migration tube into by carrier gas in the lump, and generate product ion in migration tube;
For showing ion mobility more intuitively, we can show the form that described relative ion mobility is made spectral line, for this reason,
The ion mobility spectrometry of the known substance preserved in the ion mobility spectrometry of described sample molecule and the database is compared differentiation, and show recognition result.Wherein, the ion mobility spectrometry of the known substance of preserving in the described database is the ion mobility spectrometry database that relative ion mobility that the ion mobility of ion mobility by known substance and known substance A obtains forms.
In step 24, ion mobility and the relative ion mobility that the ion mobility of known substance A obtains according to described sample molecule comprise:
According to
Perhaps
Obtain relative ion mobility, wherein,
Be relative ion mobility,
Be the ion mobility of the sample molecule that contains in the detected material,
Ion mobility for known substance A.
As seen, relative ion mobility
, with migration tube temperature, migration gas humidity, air-flow magnetic field homogeneity and no longer relevant, the promptly relative ion mobility of field uniformity
No longer be subjected to having overcome the technological deficiency that exists in the prior art described in the background technology by migration gas temperature, migration gas humidity, migration gas flowfield homogeneity and the testing environment of these parameter controls of field uniformity and the restriction of migration tube device manufacturing process.Make the ion mobility spectrometry database that uses relative ion mobility to set up also have versatility.
Above-mentioned known substance A is can be water vapour, oxygen or other any known substance.
In step 25, described demonstration recognition result comprises:
If consistent ion mobility spectrometry is arranged, then show this material title, if there is not consistent ion mobility spectrometry, also shows and do not contain any known substance.
Like this, utilize the described method of utilizing the ion mobility spectrometry recognition material of present embodiment, at first set up the ion mobility spectrometry database of a multiple material, the ion mobility spectrometry of preserving in this database also is to be formed by relative ion mobility, promptly obtain relative ion mobility, form the ion mobility spectrometry database by relative ion mobility by the ion mobility of each material and the ion mobility of known substance A.
Afterwards, when carrying out material identification, obtain relative sample molecule ion mobility by the sample molecule ion mobility with known substance A ion mobility, the ion mobility spectrometry of preserving in ion mobility spectrometry that the sample molecule mobility that this is relative forms and the above-mentioned ion mobility spectrometry database compares, and draws recognition result.
In sum, the described method of utilizing the ion mobility spectrometry recognition material of present embodiment, by obtaining sample molecule ion mobility and known substance A ion mobility, and draw the mode of relative ion mobility according to described two ion mobilities, form the relative ion mobility spectrometry of sample molecule that contains in the checked property, the ion mobility spectrometry database also is a relative ion mobility spectrometry database with respect to known substance A ion mobility, and then the method for the material that carries out again containing in checked property identification, make ion mobility spectrometry become a relative value with respect to known substance A ion mobility, the restriction of no longer examined environment of this relative value and equipment, effectively overcome the defective described in the background technology, made the ion mobility spectrometry storehouse have versatility.
The above only is preferred embodiment of the present invention, and is in order to restriction the present invention, within the spirit and principles in the present invention not all, any modification of being done, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (5)
1. a method of utilizing the ion mobility spectrometry recognition material is characterized in that, comprising:
The heating detected material, the sample molecule and the known substance A that contain in its gasification back detected material bring migration tube into by carrier gas in the lump, and generate product ion in migration tube;
The Faraday detector detects gas current and amplifies through amplifier, and via after the conversion of A/D sampling thief digital-to-analogue, exports to data processing unit;
Data processing unit calculates the ion mobility of described sample molecule and the ion mobility of known substance A, and obtains the relative ion mobility of sample molecule according to described two ion mobilities;
The ion relative mobility of the known substance preserved in the ion relative mobility of described sample molecule and the database is compared differentiation, and the demonstration recognition result, the ion relative mobility of the known substance of preserving in the described database is the relative ion mobility database by the relative ion mobility formation of the ion mobility acquisition of the ion mobility of known substance and known substance A.
2. method according to claim 1 is characterized in that, also comprises: after the relative ion mobility of described acquisition sample molecule, formed the ion relative mobility spectrum of described sample molecule by this relative ion mobility;
The ion relative mobility spectrum of the known substance preserved in the ion relative mobility of described sample molecule spectrum and the database is compared differentiation, and the demonstration recognition result, the ion relative mobility spectrum of the known substance of preserving in the described database is the relative ion mobility spectrometry database by the relative ion mobility formation of the ion mobility acquisition of the ion mobility of known substance and known substance A.
3. according to claim 1 or 2 described methods, it is characterized in that described ion mobility and the relative ion mobility that the ion mobility of known substance A obtains according to described sample molecule comprise:
According to
Perhaps
Obtain relative ion mobility, wherein,
Be relative ion mobility,
Be the ion mobility of the sample molecule that contains in the detected material,
Ion mobility for known substance A.
4. according to claim 1 or 2 described methods, it is characterized in that described known substance A is water vapour or oxygen.
5. method according to claim 1 is characterized in that, described demonstration recognition result comprises:
If consistent ion mobility spectrometry is arranged, then show this material title, if there is not consistent ion mobility spectrometry, also shows and do not contain any known substance.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110175660 CN102253112B (en) | 2011-06-27 | 2011-06-27 | Method for identifying substance by relative ion mobility spectrum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110175660 CN102253112B (en) | 2011-06-27 | 2011-06-27 | Method for identifying substance by relative ion mobility spectrum |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102253112A true CN102253112A (en) | 2011-11-23 |
| CN102253112B CN102253112B (en) | 2013-05-22 |
Family
ID=44980494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110175660 Expired - Fee Related CN102253112B (en) | 2011-06-27 | 2011-06-27 | Method for identifying substance by relative ion mobility spectrum |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102253112B (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102313776A (en) * | 2011-07-27 | 2012-01-11 | 武汉矽感科技有限公司 | Ion mobility spectrometry |
| CN103091390A (en) * | 2013-01-05 | 2013-05-08 | 武汉矽感科技有限公司 | Method for rapidly detecting clenbuterol hydrochloride inside animal body |
| CN103149270A (en) * | 2013-02-27 | 2013-06-12 | 武汉矽感科技有限公司 | Method for detecting grease by utilizing ion mobility spectrometer |
| CN103868981A (en) * | 2012-12-12 | 2014-06-18 | 中国科学院大连化学物理研究所 | Method for qualitative identification of one or more than two specific substances in sample |
| CN103884767A (en) * | 2012-12-21 | 2014-06-25 | 中国科学院大连化学物理研究所 | Method for improvement of ion mobility spectrometer identification detection performance |
| CN104007164A (en) * | 2014-05-29 | 2014-08-27 | 武汉矽感科技有限公司 | Use of ion mobility spectrometer for detecting gibberellins residues in crops and method for detecting gibberellins residues in crops |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002096805A2 (en) * | 2001-05-28 | 2002-12-05 | Michael Karas | Separation of components of an analysis sample in an ion mobility spectrometer using a supply of selectively interactive gaseous particles |
| US6815669B1 (en) * | 1999-07-21 | 2004-11-09 | The Charles Stark Draper Laboratory, Inc. | Longitudinal field driven ion mobility filter and detection system |
| CN1759312A (en) * | 2003-03-07 | 2006-04-12 | 气体感觉分析有限责任公司 | Method and test system for detecting harmful substances |
-
2011
- 2011-06-27 CN CN 201110175660 patent/CN102253112B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6815669B1 (en) * | 1999-07-21 | 2004-11-09 | The Charles Stark Draper Laboratory, Inc. | Longitudinal field driven ion mobility filter and detection system |
| WO2002096805A2 (en) * | 2001-05-28 | 2002-12-05 | Michael Karas | Separation of components of an analysis sample in an ion mobility spectrometer using a supply of selectively interactive gaseous particles |
| CN1759312A (en) * | 2003-03-07 | 2006-04-12 | 气体感觉分析有限责任公司 | Method and test system for detecting harmful substances |
Non-Patent Citations (3)
| Title |
|---|
| 《中国优秀博硕士学位论文全文数据库（硕士）社学科学I辑》 20061031 吕勇杰 离子迁移谱技术及其在毒品和爆炸物检测中的应用 第9-10，16-23页 1-5 , 第10期 * |
| 《化学试剂》 20110228 疏天民 等 离子迁移谱技术及其化学校准物概述 全文 1-5 第33卷, 第2期 * |
| 《警察技术》 20070630 何山 爆炸物探测技术 第63页 1-5 , * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102313776A (en) * | 2011-07-27 | 2012-01-11 | 武汉矽感科技有限公司 | Ion mobility spectrometry |
| CN102313776B (en) * | 2011-07-27 | 2013-07-17 | 武汉矽感科技有限公司 | Ion mobility spectrometry |
| CN103868981A (en) * | 2012-12-12 | 2014-06-18 | 中国科学院大连化学物理研究所 | Method for qualitative identification of one or more than two specific substances in sample |
| CN103884767A (en) * | 2012-12-21 | 2014-06-25 | 中国科学院大连化学物理研究所 | Method for improvement of ion mobility spectrometer identification detection performance |
| CN103884767B (en) * | 2012-12-21 | 2016-05-18 | 中国科学院大连化学物理研究所 | A kind of method that improves ionic migration spectrometer recognition detection performance |
| CN103091390A (en) * | 2013-01-05 | 2013-05-08 | 武汉矽感科技有限公司 | Method for rapidly detecting clenbuterol hydrochloride inside animal body |
| CN103149270A (en) * | 2013-02-27 | 2013-06-12 | 武汉矽感科技有限公司 | Method for detecting grease by utilizing ion mobility spectrometer |
| CN103149270B (en) * | 2013-02-27 | 2015-07-22 | 上海矽感信息科技（集团）有限公司 | Method for detecting grease by utilizing ion mobility spectrometer |
| CN104007164A (en) * | 2014-05-29 | 2014-08-27 | 武汉矽感科技有限公司 | Use of ion mobility spectrometer for detecting gibberellins residues in crops and method for detecting gibberellins residues in crops |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102253112B (en) | 2013-05-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102253112B (en) | Method for identifying substance by relative ion mobility spectrum | |
| EP3011585B1 (en) | Method and device for ionizing particles of a sample gas flow | |
| CN101738429B (en) | Ion separation, enrichment and detection device | |
| CN101339160B (en) | Plasma source ion synergic checking ion transfer spectrometer | |
| CN102680999B (en) | Automatic temperature/humidity compensation method of electrostatic collecting radon detection efficiency | |
| CN104713845B (en) | Mixture component identification method based on terahertz absorption spectrum datum processing | |
| CN108072690B (en) | Ion mobility spectrometry and ion trap mass spectrometry combined device and analysis method | |
| CN104251846A (en) | Discriminant analysis combined laser-induced breakdown spectroscopy quantitative analysis method | |
| CN110108778B (en) | UV-FAIMS quantitative detection method for volatile organic compounds | |
| CN202111053U (en) | Surface extraction chemical ionization source | |
| CN104713945A (en) | Method for detecting explosive peroxide TATP | |
| Miyashita et al. | Time-resolved ICP-MS measurement: a new method for elemental and multiparametric analysis of single cells | |
| Kangasluoma et al. | Laboratory verification of a new high flow differential mobility particle sizer, and field measurements in Hyytiälä | |
| US20150115147A1 (en) | Drift tube ion mobility spectrometer for aerosol measurement | |
| Wang et al. | Observation of incipient particle formation during flame synthesis by tandem differential mobility analysis-mass spectrometry (DMA-MS) | |
| Kontkanen et al. | Estimating the contribution of ion–ion recombination to sub-2 nm cluster concentrations from atmospheric measurements | |
| Kallinger et al. | Analysis and handling of bio-nanoparticles and environmental nanoparticles using electrostatic aerosol mobility | |
| US9691594B2 (en) | Method for analysis of sample and apparatus therefor | |
| CN107085061A (en) | The absolute quantification analysis method of lysophosphatidyl choline based on HPLC MS/MS detection platforms | |
| Sakurai et al. | Evaluation of uncertainties in femtoampere current measurement for the number concentration standard of aerosol nanoparticles | |
| Liu et al. | Size-resolved chemical composition analysis of ions produced by a commercial soft X-ray aerosol neutralizer | |
| CN101936946A (en) | Method for detecting melamine in foods or feeds by using ion mobility spectrometry (IMS) technology | |
| CN103884767B (en) | A kind of method that improves ionic migration spectrometer recognition detection performance | |
| CN105390364A (en) | Mass spectrum apparatus capable of detecting neutral molecule products and ion products, and operating method thereof | |
| CN105785426A (en) | Space neutral atom imaging instrument calibration method and device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SHANGHAI SYSCAN INFORMATION TECHNOLOGY (GROUP) CO. Effective date: 20140928 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20140928 Address after: 430000, No. 4, Wu Nan Road, Taiwan business investment zone, Dongxihu District, Hubei, Wuhan Patentee after: WUHAN SYSCAN TECHNOLOGY Co.,Ltd. Patentee after: SHANGHAI SYSCAN INFORMATION TECHNOLOGY GROUP Co.,Ltd. Address before: 430000, No. 4, Wu Nan Road, Taiwan business investment zone, Dongxihu District, Hubei, Wuhan Patentee before: WUHAN SYSCAN TECHNOLOGY Co.,Ltd. |
|
| ASS | Succession or assignment of patent right |
Owner name: WUHAN SYSCAN DIGITAL CO., LTD. Free format text: FORMER OWNER: SHANGHAI SYSCAN INFORMATION TECHNOLOGY (GROUP) CO., LTD. Effective date: 20150407 Owner name: SHANGHAI SYSCAN INFORMATION TECHNOLOGY (GROUP) CO. Free format text: FORMER OWNER: WUHAN XIGAN SCI. + TECH. CO., LTD. Effective date: 20150407 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 430000 WUHAN, HUBEI PROVINCE TO: 201203 PUDONG NEW AREA, SHANGHAI |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20150407 Address after: 201203, Shanghai Zhangjiang hi tech park, 501 East Road, 7 floor, room 3000 Patentee after: SHANGHAI SYSCAN INFORMATION TECHNOLOGY GROUP Co.,Ltd. Patentee after: SHENZHEN SYSCAN TECHNOLOGY Co.,Ltd. Address before: 430000, No. 4, Wu Nan Road, Taiwan business investment zone, Dongxihu District, Hubei, Wuhan Patentee before: WUHAN SYSCAN TECHNOLOGY Co.,Ltd. Patentee before: SHANGHAI SYSCAN INFORMATION TECHNOLOGY GROUP Co.,Ltd. |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20151201 Address after: 430000, No. 31, Wuhuan Avenue, Dongxihu District, Hubei, Wuhan Patentee after: WUHAN SYSCAN TECHNOLOGY Co.,Ltd. Address before: 201203, Shanghai Zhangjiang hi tech park, 501 East Road, 7 floor, room 3000 Patentee before: SHANGHAI SYSCAN INFORMATION TECHNOLOGY GROUP Co.,Ltd. Patentee before: SHENZHEN SYSCAN TECHNOLOGY Co.,Ltd. |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20190719 Address after: 518000 Tairan Science Park 213 Building 3BV6-2, Tairan 4 Road, Tian'an Community, Shatou Street, Futian District, Shenzhen City, Guangdong Province Patentee after: Shenzhen Securities Spectrum Intelligent Technology Co.,Ltd. Address before: 430000, No. 31, Wuhuan Avenue, Dongxihu District, Hubei, Wuhan Patentee before: WUHAN SYSCAN TECHNOLOGY Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130522 |