CN102247222A - Soft artificial intraocular lens device - Google Patents

Soft artificial intraocular lens device Download PDF

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Publication number
CN102247222A
CN102247222A CN2010101738823A CN201010173882A CN102247222A CN 102247222 A CN102247222 A CN 102247222A CN 2010101738823 A CN2010101738823 A CN 2010101738823A CN 201010173882 A CN201010173882 A CN 201010173882A CN 102247222 A CN102247222 A CN 102247222A
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Prior art keywords
artificial intraocular
loop
intraocular lenses
rear surface
optics
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CN2010101738823A
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CN102247222B (en
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解江冰
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Abbott (Beijing) Medical Technology Co., Ltd.
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EYEBRIGHT (BEIJING) MEDICAL TECHNOLOGY Co Ltd
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Abstract

The invention provides a soft artificial intraocular lens device, which comprises an optical part made of a soft material and at least one supporting loop, wherein the optical part has a front surface and a rear surface; the rear surface is divided into a central area and a peripheral area; the supporting loop is made of a soft material, connected into a whole with the optical part and in an open-loop state; the supporting loop and the optical plane of the artificial intraocular lens form a certain angle, for example an angle of 1 to 20 degrees; the near end of the rear surface of the supporting loop has a right-angle edge stepped structure; and the far end of the rare surface of the supporting loop has a right-angle edge stepped structure.

Description

Soft artificial intraocular lenses's device
Technical field
This invention is about the soft artificial intraocular lenses's device of a kind of improved single type, this device can improve the stability of artificial intraocular lenses in capsule, reduce the probability of back capsule muddiness, reduce artificial intraocular lenses's adherent probability between loop and the optics in folding implantation process.
Background technology
The artificial intraocular lenses is a kind of artificial lens that can implant ophthalmic, is used for replacing the mineral crystal that becomes the human eye of muddiness because of the cataract disease, perhaps is used for refractive surgery to correct the vision of human eye.Artificial intraocular lenses's form normally is made up of the support loop of a circular optics and periphery.Optics is to be made by transparent macromolecular material.These macromolecular materials can be hard, also can be soft.Artificial intraocular lenses by hard material is made must could implant ophthalmic by a bigger otch (usually greater than 6 millimeters), so be eliminated substantially in developed country.Artificial intraocular lenses by soft material is made also often is known as collapsible artificial intraocular lenses, can implant ophthalmic by a less otch (from less than 2 millimeters to 3 millimeters) in folding or the back of curling.The flexible material that is used to prepare collapsible artificial intraocular lenses at present mainly is divided into silica gel, several classes such as hydrophilic acrylate's (hydrogel) and hydrophobic acrylic acid's ester.
Press the combination of optics and support loop, soft collapsible artificial intraocular lenses is divided into three-member type and single type usually.For example United States Patent (USP) 5,118, and 452 provide a kind of three-member type artificial intraocular lenses's device, are made up of optics and two the support loops of being made by flexible material of being made by hard material.Three-member type artificial intraocular lenses's processing relative complex is because need be inserted into additional process in the optics supporting loop.And the support loop of being made by hard thermoplastic (such as methyl methacrylate) stress relaxation phenomenon can occur in the life-time service process.In addition, this hard support loop is folding or bending easily in the operation implantation process, can bring difficulty and bring injury to patient's eyes to operation.The soft collapsible artificial intraocular lenses of single type, its optics and support loop are an integral body, are made by same flexible material.The soft collapsible artificial intraocular lenses of early stage single type such as United States Patent (USP) 4,664,666, adopts board-like design, is also referred to as closed support loop design.This board-like design has increased artificial intraocular lenses's cumulative volume, is unfavorable for little otch implant surgery.And the soft collapsible artificial intraocular lenses of up-to-date single type such as United States Patent (USP) 5,716,403, adopts open support loop design.This design is easy to processing and operation is implanted.
But the single type artificial intraocular lenses of the open support loop design of this employing, the active force between its support loop and the capsule is far below three-member type artificial intraocular lenses and board-like artificial intraocular lenses.If the active force that supports between loop and the capsule is low excessively, phenomenons such as the artificial intraocular lenses may rotate within the eye, is offset, inclination influence patient's vision.Some adopts the single type artificial intraocular lenses of open support loop design, such as United States Patent (USP) 5,716,403, supporting even place of loop and optics, adopted the hinge type design, when being subjected to bag pressure and contracting, artificial intraocular lenses's optics can not protrude to the anterior chamber with expectation artificial intraocular lenses's support loop.But, this articulated junction, thickness and width are all little than the neighboring area, have therefore reduced the active force that supports between loop and the capsule more.
Tool is in folding implantation process with the single type artificial intraocular lenses's of open support loop another one problem, and supporting loop may stick on the optics, and can not in time open, even can not open automatically forever, has greatly increased the complexity of operation.
Back capsule muddiness is also referred to as the secondary cataract, is that the artificial intraocular lenses implants a kind of common complication in back.Back capsule muddiness is because cause between the capsule residual lens epithelial cell proliferation is moved to the artificial intraocular lenses behind the cataract operation rear surface and back.Optics the artificial intraocular lenses adopts the sharp right edge, as United States Patent (USP) 6,162,249 and 6,468,306, be proved to be a kind of method that can effectively reduce back capsule muddiness because this design can stop the lens epithelial cell migration between artificial intraocular lenses's the rear surface and back capsule (referring to people's such as Buehl article, Journal ofCataract and Refractive Surgery, 34 volumes, the 1976-1985 page or leaf).This optics with sharp right edge is realized than being easier on the three-member type artificial intraocular lenses, because it is very thin to support loop, and is inserted on the optics.Realize relatively difficulty of sharp right edge on the single type artificial intraocular lenses, because it supports loop and optics is connected as a single entity, and because the support loop is that soft material is made, the broad that need do is thicker.Realize the sharp right edge on the single type artificial intraocular lenses, the edge of optics is thick, and supporting loop will approach, and perhaps square edge step drop is little.If the edge of optics is too thick, can increase artificial intraocular lenses's cumulative volume, strengthen the difficulty of small incision surgery; If it is too thin to support loop, the active force between it and the capsule is not enough, and the artificial intraocular lenses can be built on the sand in capsule; If square edge step drop is too little, the migration that stops the lens epithelial cell is not had effect.
Therefore, a kind of good artificial intraocular lenses's device needs to guarantee the stability of artificial intraocular lenses in capsule, reduces the probability of back capsule muddiness, guarantees that the artificial intraocular lenses can in time open after implanting eyes, can not support the phenomenon that loop and optics bond together.
Summary of the invention
This invention is about a kind of improved soft artificial intraocular lenses's device of single type with open support loop design.This device can improve the stability of artificial intraocular lenses in capsule at near-end that supports loop and the square edge that far-end respectively has a step, reduces the probability of back capsule muddiness, and reduces artificial intraocular lenses's adhesion strength between loop and the optics in folding implantation process.
Therefore a purpose of this invention is to provide a plurality of strong points between artificial intraocular lenses and back capsule, has improved the stability of artificial intraocular lenses in capsule.
Another purpose of this invention is to utilize the square edge design of the step that supports loop near-end and far-end, stops the proliferation apoptosis of lens epithelial cell.
It is to cause a space when the artificial intraocular lenses is folding between its optic and support loop that this invention also has a purpose.
The invention provides a kind of soft artificial intraocular lenses's device, it comprises:
-the optics made by flexible material; Wherein, optics is divided into front surface and rear surface, and wherein front surface is meant and implants behind the human eye towards outer surface, i.e. the surface that arrives earlier of extraneous light, rear surface are meant implants behind the human eye towards the surface of inside, promptly towards amphiblestroid surface; The rear surface is divided into central area and surrounding zone;
-at least one is that made by flexible material and that optics is connected as a single entity, open cyclic support loop; Wherein, support loop and intraocular lens optic plane at an angle, as the 1-20 degree; The proximal end of supporting the rear surface of loop has the square edge staircase structural model; The far-end that supports the rear surface of loop has the square edge staircase structural model.
A kind of preferred embodiment according to the present invention, the distance between the square edge staircase structural model of the square edge staircase structural model of support proximal end, loop rear surface and support loop rear surface far-end is at least 1.5 millimeters.
Another preferred embodiment according to the present invention is the 0.1-5 millimeter at the step drop of the square edge staircase structural model that supports proximal end, loop rear surface, preferred 0.3-3 millimeter, more preferably 0.5-2 millimeter.
Another preferred embodiment according to the present invention, the step drop height that supports the square edge staircase structural model of loop rear surface far-end is the 0.1-5 millimeter, preferred 0.1-1 millimeter, more preferably 0.2-0.5 millimeter.
Another preferred embodiment according to the present invention, optics and support loop are an integral body of being made by same material.
Another preferred embodiment according to the present invention, the front surface and/or the rear surface of optics comprise optical device, such as, be selected from aspheric surface equipment, many focus device, toroid equipment, colourless be casually arranged be equipped with, zoom point device, the conventional suitable various device of light filter plant or this area.
Another preferred embodiment according to the present invention, flexible material is selected from silica gel, hydrogel and soft polyacrylate.
Another preferred embodiment according to the present invention, surrounding zone, rear surface 34 thick at least 0.2 millimeter than the edge of central area.
Another preferred embodiment according to the present invention, the proximal end of supporting loop has open slot.
The invention still further relates to the above-mentioned application of artificial intraocular lenses's device in productive manpower crystal.
The purpose that can amplify according to following legend and explanation, performance, characteristics etc. in addition are all in this scope of invention.
Description of drawings
Fig. 1 is the rear surface upward view of a kind of artificial intraocular lenses's device according to the present invention.
Fig. 2 is the side vision figure that shows artificial intraocular lenses's device among Fig. 1.
The specific embodiment
Following embodiment just is used for further explaining this technological invention, but this technological invention is not limited to following embodiment.Any variation on this embodiment basis, as long as meet the spirit and the scope of this invention, all may be in the covering scope of this patent.
In Fig. 1 and Fig. 2, artificial intraocular lenses's device 10 is made by soft, Foldable material, such as silica gel, and hydrogel, soft polyacrylate material or this area routine are used for the material of this purposes.Comprise artificial intraocular lenses's device 10 optics 12 and at least one support loop 14 to be formed, and wherein optics 12 and support loop 14 are an integral body of being made by same material.Optics 12 is divided into front surface 16 and rear surface 18.Front surface 16 and/or rear surface 18 can comprise any optical device 30 according to the situation and/or the requirement of user, such as, be selected from aspheric surface equipment, many focus device, toroid equipment, colourless be casually arranged be equipped with, zoom point device, the conventional suitable various device of light filter plant or this area.Rear surface 18 is made up of central area 32 and surrounding zone 34, and wherein surrounding zone 34 may be than the edge of central area 32 36 thick at least 0.2 millimeter, so that near the optics place square edge staircase structural model 20 is set in the rear surface of supporting loop 14.The step drop of square edge staircase structural model 20 is 0.1-5 millimeters, preferred 0.3-3 millimeter, most preferably 0.5-2 millimeter.This square edge staircase structural model 20 helps stopping the rear surface 18 of the proliferation apoptosis of lens epithelial cell to optics 12, thereby reduces the probability of back capsule muddiness.The support loop 14 of artificial intraocular lenses's device is angled with intraocular lens optic plane (optical flat and optic axis 22 are vertical), general any suitable angle can, preferably 1-20 degree, most preferably 5-10 degree.Support loop 14 with above-mentioned angle can guarantee artificial crystal unit when being subjected to capsule squeezing action power, and optics is to eye rear protrusion or mobile.Support the near-end (that is, supporting the end of loop) of loop 14, open slot 24 is set, in order to as a power transmission fulcrum near optics.When supporting loop 14 and be subjected to peripheral capsule extruding, can be the fulcrum axial rotation with open slot 24, and stress can not passed to optics 12, thereby guarantee optics 12 stability within the eye.Support the far-end (that is, supporting the end of loop) of the rear surface of loop 14 and locate,, be provided with square edge staircase structural model 28 in addition from 20 at least 1.5 millimeters places of proximal end square edge structure away from optics.The step drop of square edge staircase structural model 20 is the 0.1-5 millimeter, preferred 0.1-1 millimeter, most preferably 0.2-0.5 millimeter.Square edge staircase structural model 28 can further stop the proliferation apoptosis of lens epithelial cell to rear surface 18, and can improve the stability of artificial intraocular lenses's device in capsule supporting strong point of manufacturing between loop 14 and the back capsule.In addition, when artificial intraocular lenses's device when folding, this staircase structural model can and support between the loop 14 and cause certain space at its optics 12, thereby reduces the adhesion strength between them, helps supporting loop 14 and opens automatically after artificial intraocular lenses's device is implanted.

Claims (10)

1. soft artificial intraocular lenses's device, it comprises:
-the optics made by flexible material; Wherein, optics is divided into front surface and rear surface; The rear surface is divided into central area and surrounding zone;
-at least one is that made by flexible material and that optics is connected as a single entity, open cyclic support loop; Wherein, support loop and intraocular lens optic plane at an angle, as the 1-20 degree; The proximal end of supporting the rear surface of loop has the square edge staircase structural model; The far-end that supports the rear surface of loop has the square edge staircase structural model.
2. artificial intraocular lenses's device according to claim 1 wherein supports the square edge staircase structural model of proximal end, loop rear surface and the distance that supports between the square edge staircase structural model of loop rear surface far-end is at least 1.5 millimeters.
3. artificial intraocular lenses's device according to claim 1 and 2, wherein the step drop at the square edge staircase structural model that supports proximal end, loop rear surface is the 0.1-5 millimeter, preferred 0.3-3 millimeter, more preferably 0.5-2 millimeter.
4. according to any one described artificial intraocular lenses's device of claim 1-3, the step drop height that wherein supports the square edge staircase structural model of loop rear surface far-end is the 0.1-5 millimeter, preferred 0.1-1 millimeter, more preferably 0.2-0.5 millimeter.
5. according to any one described artificial intraocular lenses's device of claim 1-4, wherein optics and support loop are an integral body of being made by same material.
6. according to any one described artificial intraocular lenses's device of claim 1-5, wherein the front surface of optics and/or rear surface comprise optical device, such as, be selected from aspheric surface equipment, many focus device, toroid equipment, colourless be casually arranged be equipped with, zoom point device, the conventional suitable various device of light filter plant or this area.
7. according to any one described artificial intraocular lenses's device of claim 1-6, wherein flexible material is selected from silica gel, hydrogel and soft polyacrylate.
8. according to any one described artificial intraocular lenses's device of claim 1-7, wherein surrounding zone, rear surface 34 is at least 0.2 millimeter than the edge of central area is thick.
9. according to any one described artificial intraocular lenses's device of claim 1-8, the proximal end of wherein supporting loop has open slot.
10. according to any one described artificial intraocular lenses's device application in productive manpower crystal of claim 1-9.
CN201010173882.3A 2010-05-17 2010-05-17 Soft artificial intraocular lens device Active CN102247222B (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102599992A (en) * 2012-03-16 2012-07-25 无锡蕾明视康科技有限公司 Artificial lens with iris diaphragm
WO2014172816A1 (en) * 2013-04-22 2014-10-30 爱博诺德(北京)医疗科技有限公司 Aspherical intraocular lens
CN106901871A (en) * 2015-12-23 2017-06-30 爱博诺德(北京)医疗科技有限公司 Intraocular lens with one or more extentions
CN106955172A (en) * 2017-03-31 2017-07-18 何伟 With the back room artificial lens for improving pouch stability reduction post gelating time edge
CN107157620A (en) * 2012-12-06 2017-09-15 诺华股份有限公司 Edge designs for reducing the luminous effect in intraocular lens
CN107865712A (en) * 2016-09-23 2018-04-03 人类光学股份公司 Artificial lens
CN108670500A (en) * 2018-06-06 2018-10-19 姚涛 Type artificial lens is auxiliarily fixed in a kind of preceding Nang Kou
WO2020063826A1 (en) * 2018-09-29 2020-04-02 东莞东阳光科研发有限公司 Intraocular lens semi-finished product forming mold, forming method and intraocular lens semi-finished product

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102599992A (en) * 2012-03-16 2012-07-25 无锡蕾明视康科技有限公司 Artificial lens with iris diaphragm
CN107157620A (en) * 2012-12-06 2017-09-15 诺华股份有限公司 Edge designs for reducing the luminous effect in intraocular lens
CN107157620B (en) * 2012-12-06 2019-12-10 诺华股份有限公司 Edge design for reducing light effects in intraocular lenses
WO2014172816A1 (en) * 2013-04-22 2014-10-30 爱博诺德(北京)医疗科技有限公司 Aspherical intraocular lens
CN106901871A (en) * 2015-12-23 2017-06-30 爱博诺德(北京)医疗科技有限公司 Intraocular lens with one or more extentions
CN106901871B (en) * 2015-12-23 2021-08-24 爱博诺德(北京)医疗科技股份有限公司 Intraocular lens with one or more additional portions
CN107865712A (en) * 2016-09-23 2018-04-03 人类光学股份公司 Artificial lens
CN106955172A (en) * 2017-03-31 2017-07-18 何伟 With the back room artificial lens for improving pouch stability reduction post gelating time edge
CN108670500A (en) * 2018-06-06 2018-10-19 姚涛 Type artificial lens is auxiliarily fixed in a kind of preceding Nang Kou
WO2020063826A1 (en) * 2018-09-29 2020-04-02 东莞东阳光科研发有限公司 Intraocular lens semi-finished product forming mold, forming method and intraocular lens semi-finished product

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Address after: 102200 No. 9 Xingchang Road, Changping District Science and Technology Park, Beijing

Patentee after: Abbott (Beijing) Medical Technology Co., Ltd.

Address before: 102200, Beijing Changping District science and Technology Park, super Road, No. 6, building 37, 1 North Zone

Patentee before: Eponode (Beijing) Medical Technology Co., Ltd.