CN102228541B - Chinese medicinal preparation for treating chronic rhinosinusitis - Google Patents

Chinese medicinal preparation for treating chronic rhinosinusitis Download PDF

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Publication number
CN102228541B
CN102228541B CN2011101814906A CN201110181490A CN102228541B CN 102228541 B CN102228541 B CN 102228541B CN 2011101814906 A CN2011101814906 A CN 2011101814906A CN 201110181490 A CN201110181490 A CN 201110181490A CN 102228541 B CN102228541 B CN 102228541B
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radix
root
treatment
chronic rhinosinusitis
chinese medicine
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CN102228541A (en
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万京明
刘明秋
邹连琦
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Abstract

The invention discloses a Chinese medicinal preparation for treating chronic rhinosinusitis, which is characterized by being prepared from the following raw Chinese medicinal herbs in percentage by weight, 6.7-10.2 % of magnolia flower, 6.7-10.2 % of dark plum, 3.4-6.8 % of dahurian angelica root, 6.7-10.2 % of siberian cocklour fruit, 15.3-18.6 % of astragalus root, 6.7-10.2 % of chrysanthemum, 6.7-10.2 % of Chinese thorowax root, 3.4-6.8 % of cicada slough, 3.4-6.8 % of honey-fried Chinese ephedra, 6.8-10.2 % of honey-fried licorice root, 6.8-10.2 % of paniculate swallowwort root and 6.8-10.2 % of India madder root. The Chinese medicinal preparation for treating chronic rhinosinusitis has the advantages of reasonable formulation, convenience for taking, no toxic or side effects, has the functions of increasing immunity, shortening the curing time for chronic rhinosinusitis and improving a therapeutic effect, and can be widely used for treating the chronic rhinosinusitis.

Description

The Chinese medicine preparation of treatment chronic sinusitis
Technical field
The present invention relates to Chinese medicine preparation, particularly treat the Chinese medicine preparation of chronic sinusitis.
Background technology
Chronic sinusitis is a kind of commonly encountered diseases, frequently-occurring disease, and its clinical symptoms is: nasal obstruction, rhinorrhea, olfactory disorder, headache.Chronic sinusitis is difficult to thoroughly to cure, and often in the clinical treatment outbreak repeatedly occurs, usually because of acute sinusitis show effect repeatedly thoroughly cure do not delay due to.Common Therapeutic Method, western medical treatment is many to be main to contain ephedrine vasodilation class medicine; That many, the removing dampness sensible with lung qi dispersing of Chinese traditional treatment are dispelled is turbid, the treatment by Chinese herbs of heat-clearing and toxic substances removing, QI invigorating lung moistening.With regard to the Chinese medicine of present employed treatment chronic sinusitis, the cure rate in the short time is still lower, so general treatment is longer the course of treatment.
Summary of the invention
The object of the present invention is to provide a kind of for treating the Chinese medicine preparation that chronic sinusitis can improve therapeutic effect, shorten the treatment chronic sinusitis of the course of treatment.
For reaching above purpose, the technical scheme that the present invention adopted is: the Chinese medicine preparation of this treatment chronic sinusitis is characterized in that: processed by following raw material of Chinese medicine by weight percentage:
Flos Magnoliae 6.7-10.2%, Fructus Mume 6.7-10.2%, Radix Angelicae Dahuricae 3.4-6.8%,
Fructus Xanthii 6.7-10.2%, Radix Astragali 15.3-18.6%, Flos Chrysanthemi 6.7-10.2%,
Radix Bupleuri 6.7-10.2%, Periostracum Cicadae 3.4-6.8%, moxibustion Herba Ephedrae 3.4-6.8%,
Radix Glycyrrhizae Preparata 6.8-10.2%, Radix Cynanchi Paniculati 6.8-10.2%, Radix Rubiae 6.8-10.2%.
The present invention is also through following measure enforcement: the Chinese medicine preparation of described treatment chronic sinusitis, adopt slow fire boiling, and filter the back and concentrate, in the bottle of packing into, every bottle of 250ml, the Mel of adding 10ml in every bottle encapsulates subsequent use in addition.
The Chinese medicine preparation of described treatment chronic sinusitis, process by following raw material of Chinese medicine by weight percentage: Flos Magnoliae 8%, Fructus Mume 8%, the Radix Angelicae Dahuricae 5%,
Fructus Xanthii 9%, the Radix Astragali 17%, Flos Chrysanthemi 9%,
Radix Bupleuri 8%, Periostracum Cicadae 5%, moxibustion Herba Ephedrae 5%,
Radix Glycyrrhizae Preparata 8%, Radix Cynanchi Paniculati 9%, Radix Rubiae 9%.
The present invention collection clinical experience for many years, and combined traditional theory of Chinese medical science, the science compatibility, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs has obtained effect preferably, the cure rate of chronic sinusitis is significantly improved, and tangible shortening has also been arranged the course of treatment.
Clinical trial analysis:
One, source of data
From year February in January, 2010 to 2011, Laiwu City the People's Hospital department of otorhinolaryngology, the department of Chinese medicine, the 80 routine chronic sinusitis patients that see and treat patients altogether, wherein women 30 examples, male 50 examples, the age, between year, its disease all met the chronic sinusitis diagnostic criteria at 20-60.
Two, chronic sinusitis diagnostic criteria
Symptom: purulence nasal mucus, nasal obstruction, headache, hyposmia or forfeiture, visual function obstacle.During diagnosis by nasal sinuses CT.
Three, instructions of taking
Employing the present invention is oral, every day early, evening each clothes once, each half bottle, i.e. 125ml.Per 15 days courses of treatment.
Forbid for the diabetes patient.For the careful usefulness of hypertensive patient.
Four, criterion of therapeutical effect
Cure: after treat 1-2 the course of treatment, on inspection, the purulence nasal mucus is had a stuffy nose, have a headache, hyposmia or
Forfeiture, visual function obstacle symptom all disappears; Nasal sinuses CT increase in density, fluid level or polyp shade disappear.
Effectively: after treating 1-2 the course of treatment, on inspection, purulence nasal mucus, nasal obstruction, headache transference cure are smelt
Feel is gone down, visual function obstacle symptom takes a turn for the better; Nasal sinuses CT increase in density, fluid level or polyp dash area disappear.
Invalid: after treating 1-2 the course of treatment, on inspection, the purulence nasal mucus, the nasal obstruction, the headache, hyposmia or
Forfeiture, visual function obstacle symptom no change; Nasal sinuses CT increase in density, fluid level or polyp shade no change.
Five, efficacy analysis
To above 80 routine patients, all adopt the present invention to treat.After treating two courses of treatment, on inspection, have 48
Example is cured, and cure rate is 60%; 30 examples are arranged effectively, and in the 3rd course of treatment, cure, total effective rate is 97.5%; Have 2 examples invalid, inefficiency is 2.5%.
Pharmacology analysis:
Flos Magnoliae: suffering, temperature.Attach to the lung and stomach meridians.Effect with dispersing wind and cold, expelling pathogenic wind and restoring the functions of orifices in face.Cure mainly headche due to wind-cold, nasal sinusitis, it is obstructed to have a stuffy nose, turbid nasal discharge, toothache.Usually with Flos Magnoliae treatment rhinitis and sinusitis.
Fructus Mume: acid, flat.Return liver, spleen, stomach, large intestine channel.Has astringing lung-QI and relieving cough, relieving diarrhea with astringents, hemostasis, the effect of promoting the production of body fluid.It is more than to cure mainly chronic cough, the chronic diarrhea chronic dysentery, and hematuria is had blood in stool, deficiency-heat excessive thirst, carbuncle sore.
The Radix Angelicae Dahuricae: suffering, temperature.Return lung, spleen, stomach warp.Effect with expelling wind and removing dampness, understand things pain-stopping, detumescence and apocenosis.Cure mainly headache, supraorbital bone pain, toothache, nasal sinusitis, nasal obstruction, domination of damp pathogen chronic diarrhea, ulcer sores.
Fructus Xanthii: bitter, sweet, hot, temperature, mild toxicity.Return lung, Liver Channel.Has dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, antipruritic effect.Cure mainly nasal sinusitis, headche due to wind-cold, rheumatic arthralgia, rubella, eczema, scabies.
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of detoxification granulation promoting.Cure mainly diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back.
Flos Chrysanthemi: sweet, bitter, be slightly cold.Return lung, Liver Channel.Have wind and heat dispersing, suppressing the hyperactive liver makes eye bright, the effect of removing toxic substances and promoting subsidence of swelling.Cure mainly affection due to external wind and heat, pathogenic wind-warm is from the beginning of, fever and headache, and is dizzy, conjunctival congestion and swelling pain, furuncle swelling toxin.
Radix Bupleuri: bitter, hot, be slightly cold.Return liver, gallbladder meridian.Having induces sweat brings down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, the effect of elevate a turnable ladder yang-energy.Cure mainly fever caused by exogenous pathogens, alternate attack of chill and fever, malaria, hypochondriac pain due to stagnation of liverQI mammary swelling, headache dizziness, menoxenia, the proctoptosis of collapse of QI, uterine prolapse, gastroptosis.
Cicada: sweet, salty, Liang .Return lung, Liver Channel.Has dispelling wind-heat, rash sore-throat relieving, the effect of expellingging wind and relieving convulsion.Cure mainly anemopyretic cold, laryngopharynx swelling and pain, it is silent to cough, measles without adequate eruption, the rubella pruritus, infantile convulsion is twitched, tetanus.
The moxibustion Herba Ephedrae: the moxibustion Herba Ephedrae is that Herba Ephedrae is used the Mel parch, hot, little hardship, temperature.Return lung, urinary bladder channel.Has relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, the effect of inducing diuresis to remove edema.Cure mainly chill exterior disease, cough and asthma, edema due to wind pathogen, dysuria, rheumatic arthralgia, numbness of the skin, rubella pruritus, carbuncle of yin nature sucutaneous nodule.
Radix Glycyrrhizae Preparata: Radix Glycyrrhizae Preparata is that Radix Glycyrrhizae is used the Mel parch, and is sweet, flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach, the asthenia lack of appetite, the anxious pain of extremity contraction, cardiopalmus, dirty dry, the consumptive lung disease cough.
Radix Cynanchi Paniculati: suffering, temperature.Return liver, stomach warp.Has expelling wind and removing dampness, promoting flow of QI and blood, the antipruritic effect of unstinging.Cure mainly rheumatic arthralgia, eczema, urticaria, venom.
Radix Rubiae: hardship, cold.Return liver, heart channel.Has cooling blood for hemostasis, the effect of blood circulation promoting and blood stasis dispelling.Cure mainly that heat in blood spitting of blood, haematemesis, hematuria are had blood in stool, metrorrhagia, amenorrhea, stable damage, rheumatic arthralgia, jaundice, carbuncle sore, hemorrhoid are swollen.
Mel is used for seasoning in the present invention, improves mouthfeel.
More than all medicines, be monarch drug with Flos Magnoliae, the Radix Angelicae Dahuricae, Fructus Xanthii, assistant is aided with Periostracum Cicadae, Radix Cynanchi Paniculati with the Radix Astragali, Flos Chrysanthemi, Radix Bupleuri, Fructus Mume, Radix Rubiae, moxibustion Herba Ephedrae, with the Radix Glycyrrhizae Preparata coordinating the actions of various ingredients in a prescription, controls, benefit is arranged, accent is arranged, and plays the effect of treatment chronic sinusitis altogether.
Beneficial effect of the present invention is: reasonable recipe, taking convenience has no side effect, and has the function that increases immunity, has shortened the healing time of chronic sinusitis, has improved therapeutic effect.
The specific embodiment
Embodiment 1
Press following each raw material of Chinese medicine of percentage by weight weighing: Flos Magnoliae 8%, Fructus Mume 8%, the Radix Angelicae Dahuricae 5%, Fructus Xanthii 9%, the Radix Astragali 17%, Flos Chrysanthemi 9%, Radix Bupleuri 8%, Periostracum Cicadae 5%, moxibustion Herba Ephedrae 5%, Radix Glycyrrhizae Preparata 8%, Radix Cynanchi Paniculati 9%, Radix Rubiae 9%.After weighing is good, adopt slow fire boiling, filter the back and concentrate, in the bottle of packing into, every bottle of 250ml, every bottle of Mel that adds 10ml encapsulates subsequent use.Once produce what of medicament, count the amount preparation of taking in 1-2 days by clinical case.
Adopt present embodiment, treat 30 cases altogether, wherein in 2 courses of treatment, cure by 24 examples, cure rate is 80%.
Model case: brother Lee, man, hot people from village of Laiwu City, 28 years old.In November, 2010 my institute's ear nose
Larynx section goes to a doctor.On inspection, tangible nasal obstruction is arranged, stickiness, purulence nasal mucus; Women's head-ornaments portion distending pain, anosmia.Through the nasal sinuses CT examination, sinus frontalis, sphenoid sinus have mucosa to thicken shadow.Take the Chinese medicine preparation of this treatment chronic sinusitis, after the course of treatment, symptom obviously alleviates, take 2 courses of treatment after, through check, symptom all disappears, nasal sinuses CT increase in density, fluid level or polyp shade disappear.After take a course of treatment again, Gu its, kind thereafter.
Embodiment 2
Press following each raw material of Chinese medicine of percentage by weight weighing: Flos Magnoliae 7%, Fructus Mume 10%, the Radix Angelicae Dahuricae 4%, Fructus Xanthii 10%, the Radix Astragali 16%, Flos Chrysanthemi 10%, Radix Bupleuri 7%, Periostracum Cicadae 6%, moxibustion Herba Ephedrae 4%, Radix Glycyrrhizae Preparata 10%, Radix Cynanchi Paniculati 7%, Radix Rubiae 9%.Formulation method is with embodiment 1.
Adopt present embodiment, treat 30 cases altogether, that wherein in 2 courses of treatment, cures has 15 examples, and cure rate is 50%.There is 1 example invalid.Remaining was cured 3-4 the course of treatment.
Model case: Wang Hua, woman, Laiwu City power plant, 38 years old.In JIUYUE, 2010, I went to a doctor at institute's department of otorhinolaryngology.When being in high school, readme gets chronic sinusitis, and bad during fashion.On inspection, tangible nasal obstruction is arranged, secretions is the pus magma; Headache, facial bloated, hyposmia.Through the nasal sinuses CT examination, sinus frontalis, sphenoid sinus have mucosa to thicken shadow, the nasal septum left avertence.Take the Chinese medicine preparation of this treatment chronic sinusitis, take 2 courses of treatment after, symptom obviously alleviates, take 3 courses of treatment after, through check, symptom all disappears, nasal sinuses CT increase in density, fluid level or polyp shade disappear, after take a course of treatment again, with solid curative effect.
Embodiment 3
Press following each raw material of Chinese medicine of percentage by weight weighing: Flos Magnoliae 10%, Fructus Mume 7%, the Radix Angelicae Dahuricae 6%, Fructus Xanthii 7%, the Radix Astragali 18%, Flos Chrysanthemi 7%, Radix Bupleuri 10%, Periostracum Cicadae 3%, moxibustion Herba Ephedrae 6%, Radix Glycyrrhizae Preparata 7%, Radix Cynanchi Paniculati 9%, Radix Rubiae 10%.After weighing is good, adopt slow fire boiling, filter the back and concentrate, in the bottle of packing into, every bottle of 250ml encapsulates subsequent use.Once produce what of medicament, count the amount preparation of taking in 1-2 days by clinical case.
Adopt present embodiment, treat 20 cases altogether, that wherein in 2 courses of treatment, cures has 9 examples, and cure rate is 45%.There is 1 example invalid.Remaining was cured 3-4 the course of treatment.
Model case: Hao Wei, woman, Laiwu City Thermal Corp, 34 years old.In December, 2010 comes me institute's department of Chinese medicine to go to a doctor.On inspection, secretions is the pus magma, and nasal mucosa is red and swollen, nasal obstruction, and it is difficult to breathe, and rhinophonia is heavy.Through the nasal sinuses CT examination, right maxillary and bilateral sphenoid sinus are seen multiple little cyst, right side hypertrophic inferior turbinate, deviation of nasal septum.Adopt the present invention, take 2 courses of treatment after, symptom obviously alleviates, take 3 courses of treatment after, through check, symptom all disappears, nasal sinuses CT increase in density, fluid level or polyp shade disappear, after take a course of treatment again, solid its, be apt to thereafter.

Claims (2)

1. treat the Chinese medicine preparation of chronic sinusitis, it is characterized in that: process by following raw material of Chinese medicine by weight percentage:
Flos Magnoliae 6.7-10.2%, Fructus Mume 6.7-10.2%, Radix Angelicae Dahuricae 3.4-6.8%,
Fructus Xanthii 6.7-10.2%, Radix Astragali 15.3-18.6%, Flos Chrysanthemi 6.7-10.2%,
Radix Bupleuri 6.7-10.2%, Periostracum Cicadae 3.4-6.8%, moxibustion Herba Ephedrae 3.4-6.8%,
Radix Glycyrrhizae Preparata 6.8-10.2%, Radix Cynanchi Paniculati 6.8-10.2%, Radix Rubiae 6.8-10.2%.
2. the Chinese medicine preparation of treatment chronic sinusitis according to claim 1 is characterized in that it and is processed by following raw material of Chinese medicine by weight percentage:
Flos Magnoliae 8%, Fructus Mume 8%, the Radix Angelicae Dahuricae 5%,
Fructus Xanthii 9%, the Radix Astragali 17%, Flos Chrysanthemi 9%,
Radix Bupleuri 8%, Periostracum Cicadae 5%, moxibustion Herba Ephedrae 5%,
Radix Glycyrrhizae Preparata 8%, Radix Cynanchi Paniculati 9%, Radix Rubiae 9%.
CN2011101814906A 2011-06-30 2011-06-30 Chinese medicinal preparation for treating chronic rhinosinusitis Expired - Fee Related CN102228541B (en)

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CN103349693B (en) * 2013-07-24 2014-09-10 李韶华 Chinese herbal medicine composition for treating allergic rhinitis
CN106177203A (en) * 2016-07-25 2016-12-07 陈凯 A kind of Chinese medicine treating chronic sinusitis
CN107213337A (en) * 2017-06-20 2017-09-29 合肥丰瑞隆生物科技有限公司 Treat Chinese medicine composition of nasosinusitis and preparation method thereof

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CN106802327A (en) * 2017-01-11 2017-06-06 合肥华润神鹿药业有限公司 It is a kind of to set up the method that youngster rushes down the finger-print for stopping pharmaceutical preparation
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