CN102225646A - Multilayer coextrusion medical blister composite packaging film and preparation method thereof - Google Patents
Multilayer coextrusion medical blister composite packaging film and preparation method thereof Download PDFInfo
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- CN102225646A CN102225646A CN2011101221385A CN201110122138A CN102225646A CN 102225646 A CN102225646 A CN 102225646A CN 2011101221385 A CN2011101221385 A CN 2011101221385A CN 201110122138 A CN201110122138 A CN 201110122138A CN 102225646 A CN102225646 A CN 102225646A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/001—Combinations of extrusion moulding with other shaping operations
- B29C48/0017—Combinations of extrusion moulding with other shaping operations combined with blow-moulding or thermoforming
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
- B29C48/09—Articles with cross-sections having partially or fully enclosed cavities, e.g. pipes or channels
- B29C48/10—Articles with cross-sections having partially or fully enclosed cavities, e.g. pipes or channels flexible, e.g. blown foils
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- Shaping By String And By Release Of Stress In Plastics And The Like (AREA)
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Abstract
The invention discloses a multilayer coextrusion medical blister composite packaging film which comprises an inner film, a middle film and an outer film; each layer from outside comprises the following components in parts by mass: 20-30 parts of outer layer made from copolymer of low-density polyethylene and linear low-density polyethylene, 20-40 parts of middle layer made from polymer of the liner low-density polyethylene and low-density metallocene polyethylene, and 30-50 parts of inner layer made from polypropylene. The product is obtained by extruding, film-blowing, air-cooling, water-cooling shaping, surface processing and winding. The multilayer coextrusion medical blister composite packaging film is safe, sanitary, transparent and airtight, has good elongation and varieties respectively suitable for three sterilizing forms, the blister forming is realized in the packaging process. The layers of the product have good compatibility, and cannot be separated from each other when performing the blister forming; and therefore, the physical mechanical property is maintained.
Description
Technical field
The present invention relates to multi-layer co-extruded packaging film and preparation method thereof, particularly relate to and be used to multi-layer co-extruded medical plastic uptake composite package film of packing medical equipment and preparation method thereof.
Background technology
The packing that the paper that medical blister plastic packaging film is mainly used in disposable preformed sterile system easily tears, moulds the medicine equipment articles for use that easily tear, its kind have the gaseous sterilization of being suitable for (oxirane EO sterilization), irradiation sterilization (alpha ray sterilization) and steam sterilizing sterilization methods such as (moise-heat sterilizations).Because of medical blister plastic packaging film is the special plastic uptake film that provides for full-automatic suction plastic packing machine, it has the favorable mechanical physical property, can with medical dialyzing paper heat seal, when tearing, do not produce paper scrap; Can also be with the heat seal of two medical blister plastic packaging films, easily openable during use.Present medical blister plastic packaging film mostly is three layers, adopt multi-layer co-extruded preparation, be fit to oxirane (EO) sterilization (investment is big, big to operator's actual bodily harm), its performance does not also reach the requirement of moise-heat sterilization (environmental protection, investment little), alpha ray sterilization (energy-saving and environmental protection).Simultaneously, present medical blister plastic packaging film is in multi-layer co-extruded preparation process, major part all can adopt polypropylene layer and linear polyethylene layer, but polypropylene layer and the high polymer of linear polyethylene layer for not melting mutually mutually, two kinds of materials can not be compound well, can produce after compound pick from, make the multi-layer co-extruded medical blister plastic packaging film of preparation in the process of plastic uptake, can produce two and be separated, reduce its physical and mechanical properties.
Summary of the invention
Weak point in the background technology, the invention provides epoxy available ethane (EO) sterilization, moise-heat sterilization or alpha ray sterilization and polypropylene layer and linear polyethylene layer can fine compound multi-layer co-extruded medical plastic uptake composite package film and preparation method thereof.
The present invention adopts following technical scheme: multi-layer co-extruded medical plastic uptake composite package film, and it comprises the interior trilamellar membrane of outer, neutralization, component of each layer and weight percentage are from outside to inside:
Skin is blend 20 ~ 30 mass fractions of low density polyethylene (LDPE) and Linear low-density polyethylene,
The middle level is LLDPE and metallocene low density polyethylene blend 20 ~ 40 mass fractions,
Internal layer is polypropylene 30 ~ 50 mass fractions,
Described cladding material low density polyethylene (LDPE) mixes by weight 1 ~ 8:1 with Linear low-density polyethylene; Middle level material LLDPE mixes by weight 1 ~ 10:1 with metallocene low density polyethylene.
Adopting LLDPE and metallocene low density polyethylene mixture because of the middle level is material, LLDPE and polyacrylic blending have been improved, make the multi-layer co-extruded medical plastic uptake composite package film for preparing in the process of plastic uptake, can not produce two and be separated, keep its physical and mechanical properties.Simultaneously, this multi-layer co-extruded medical plastic uptake composite package film is fit to gaseous sterilization (oxirane EO sterilization).
Because of in plastic uptake heat seal process, the internal layer and the outer field temperature difference can not surpass about 20 ℃, are outer so adopt the blend of low density polyethylene (LDPE) and Linear low-density polyethylene, and polypropylene is an internal layer.
Among the present invention, multi-layer co-extruded medical plastic uptake composite package film can also be five layers, and its five layers are followed successively by from top to bottom:
PA polyamide layer 10 ~ 25 mass fraction,
Adhesive phase 5 ~ 15 mass fractions,
PA polyamide layer 10 ~ 25 mass fraction,
Adhesive phase 5 ~ 15 mass fractions,
Ldpe resin or polypropylene layer 30 ~ 60 mass fractions.
Among the present invention, described polypropylene is the polymer that contains random copolymer, is commercial product, buys in Fujian combined oil chemical industry Co., Ltd, and model is 3240NC.Internal layer adopts polypropylene can make the multi-layer co-extruded medical plastic uptake composite package film behind plastic uptake softer.
The melt index of described low density polyethylene (LDPE) is 1.5 ~ 6, can with medical dialyzing paper heat seal.Polyacrylic melt index is 2.5 ~ 10, can with medical dialyzing paper heat seal.The melt index of LLDPE is 1.5 ~ 8.
Described PA polyamide layer is nylon 6 or copolymer nylon, and relative viscosity is 2 ~ 5.5.It is raw material that this layer adopts nylon 6 or copolymer nylon, has improved the temperature difference of this layer and adhesive layer, the hot strength and the angle tear strength of multi-layer co-extruded medical plastic uptake composite package film behind the increase plastic uptake.
Wherein, described copolymer nylon is the copolymer of caprolactam and acid amides 66.
Described adhesive is an ionic resin, is commercial product, purchases in French A Ke sign indicating number company, the trade mark is 18370, and it has good bonding effect, the tack temperature wide ranges, be 150 ~ 250 ℃, can make PA polyamide layer and ldpe resin or polypropylene layer height bonding.
When layer 5 adopted ldpe resin to be raw material, the multi-layer co-extruded medical plastic uptake composite package film of preparation was fit to the alpha ray sterilization.
When layer 5 adopted polypropylene layer to be raw material, the multi-layer co-extruded medical plastic uptake composite package film of preparation was fit to moise-heat sterilization, mechanical strength height behind the plastic uptake, anti-126 ~ 130 ℃ high-temperature sterilization.And it is economical and practical to fill a prescription, and can reduce production costs.
The preparation method of the multi-layer co-extruded medical plastic uptake composite package film of the present invention may further comprise the steps:
1) extrude: each layer raw material delivered to heating and melting becomes polymer melt in three layers or five-layer co-squeezing blown film unit three or five extruders, each each layer of runner component by spiral center die head closes in that the upper layer of mouth mould is stacked then, is combined into the co-extrusion film; Described three layers or five-layer co-squeezing blown film unit all adopt single screw extrusion machine, and screw slenderness ratio is 32:1, and the body temperature of extruder is 160 ~ 240 ℃, and die head temperature is 190 ~ 240 ℃, and screw speed is 15 ~ 50 rev/mins;
2) blown film: when described polymer molten fluid goes out die head, made by three layers or inflation of five-layer co-squeezing blown film unit, be drawn into film again, described blow-up ratio is 1:1.2 ~ 2.5, and draw speed is 10 ~ 30m/min;
3) air-cooled, water-cooled shaping: will adopt water-cooled shaping through the film that step 2 stretches, cooling line height is 0.5 ~ 1.0, the acute cold crystallization of cooling pattern;
4) surface treatment, rolling: will be rolled into the film volume again, through cutting, be packaged to be described multi-layer co-extruded medical plastic uptake composite package film through the film surface sided corona treatment of step 3 cooling.
In the described step 1, when raw material was five layers, described each strata compound melt flow rate (MFR) was 2 ~ 10kg/10min, and the melt pressure of polymer melt in extruder is 15 ~ 40MPa.
Body temperature in the described step 1 is 170 ~ 200 ℃.
Die head temperature in the described step 1 is 190 ~ 210 ℃.
The thickness of the multi-layer co-extruded medical plastic uptake composite package film that described step 4 obtains is 0.05 ~ 0.12mm.According to different thickness, select different screw rod and draw speed.
Adopt technical scheme of the present invention, the multi-layer co-extruded medical plastic uptake composite package film of preparation can be three layers, can also be five layers; The kind that suitable oxirane EO sterilization is not only arranged also has the kind that is fit to moise-heat sterilization or alpha ray sterilization; Also can with medical dialyzing paper heat seal, when tearing, do not produce paper scrap; Also can be with the heat seal of two medical blister plastic packaging films, easily openable during use.Adopt the preparation method of the drop-down inflation cooling of the present invention traction, the multi-layer co-extruded medical plastic uptake composite package film of preparation has good percentage elongation, satisfies the plastics sucking moulding of medical package process; When multi-layer co-extruded medical plastic uptake composite package film is three layers, adopting LLDPE and metallocene low density polyethylene mixture is middle layer material, LLDPE and polyacrylic blending have been improved, make the multi-layer co-extruded medical plastic uptake composite package film for preparing in the process of plastic uptake, can not produce two and be separated, keep its physical and mechanical properties.When multi-layer co-extruded medical plastic uptake composite package film was five layers, the middle transition adhesive layer was incrust jointing material, reached the requirement of sterilization health after the processing.
The multi-layer co-extruded medical plastic uptake composite package film safety and sanitation of the present invention preparation, transparent airtight, have and be fit to kind, the packaging process plastics sucking moulding of three kinds of sterilization methods respectively and also have good percentage elongation.Blending is good between each layer of product, can not produce two during plastics sucking moulding and be separated, and keeps physical and mechanical properties.
The specific embodiment
The present invention is further elaborated by following examples.
The present invention adopts following technical scheme: multi-layer co-extruded medical plastic uptake composite package film is characterized in that: it comprises the interior trilamellar membrane of outer, neutralization, and component of each layer and weight percentage are from outside to inside:
Skin is blend 20 ~ 30 mass fractions of low density polyethylene (LDPE) and Linear low-density polyethylene,
The middle level is LLDPE and metallocene low density polyethylene blend 20 ~ 40 mass fractions,
Internal layer is polypropylene 30 ~ 50 mass fractions,
Described cladding material low density polyethylene (LDPE) mixes by weight 1 ~ 8:1 with Linear low-density polyethylene; Middle level material LLDPE mixes by weight 1 ~ 10:1 with metallocene low density polyethylene.
Among the present invention, multi-layer co-extruded medical plastic uptake composite package film can also be five layers, and its five layers are followed successively by from top to bottom:
PA polyamide layer 10 ~ 25 mass fraction,
Adhesive phase 5 ~ 15 mass fractions,
PA polyamide layer 10 ~ 25 mass fraction,
Adhesive phase 5 ~ 15 mass fractions,
Ldpe resin or polypropylene layer 30 ~ 60 mass fractions.
Among the present invention, the preparation method of multi-layer co-extruded medical plastic uptake composite package film may further comprise the steps composition:
1) extrude: each layer raw material delivered to heating and melting becomes polymer melt in three layers or five-layer co-squeezing blown film unit three or five extruders, each each layer of runner component by spiral center die head closes in that the upper layer of mouth mould is stacked then, is combined into the co-extrusion film; Described three layers or five-layer co-squeezing blown film unit all adopt single screw extrusion machine, and screw slenderness ratio is 32:1, and the body temperature of extruder is 160 ~ 240 ℃, and die head temperature is 190 ~ 240 ℃, and screw speed is 15 ~ 50 rev/mins;
2) blown film: when described polymer molten fluid goes out die head, made by three layers or inflation of five-layer co-squeezing blown film unit, be drawn into film again, described blow-up ratio is 1:1.2 ~ 2.5, and draw speed is 10 ~ 30m/min;
3) air-cooled, water-cooled shaping: will adopt water-cooled shaping through the film that step 2 stretches, cooling line height is 0.5 ~ 1.0, the acute cold crystallization of cooling pattern;
4) surface treatment, rolling: will be rolled into the film volume again, through cutting, be packaged to be described multi-layer co-extruded medical plastic uptake composite package film through the film surface sided corona treatment of step 3 cooling.
In following examples, the detection method of thickness is: GB/T6672-2001 plastic sheeting and sheet thickness detect the mechanical measurement method.
Hot strength, the test of fracture norminal strain are by GB/T1040-2006,5 type sample requirements test;
Tear strength test is tested by the GB/T16578.1-2008 requirement;
Wherein, low density polyethylene (LDPE) is bought in Kingsoft, Shanghai petrochemical industry Co., Ltd, and model is LDPEQ281; LLDPE is bought in Fujian combined oil chemical industry Co., Ltd, and model is LLDPE7042; Polypropylene is bought in Fujian combined oil chemical industry Co., Ltd, and model is 3240NC; Adhesive is bought in French A Ke sign indicating number company, and the trade mark is 18370; Nylon 6 is bought in BASF Aktiengesellschaft, and model is B36LN, and copolymer nylon is bought in BASF Aktiengesellschaft, and model is PA6/66-C40LXO7.
Each is organized among the embodiment, the cause content of each layer component in product is in process of production determined jointly by screw speed and hauling speed, when the content of high more its individual layer of screw speed also high more, the content of fast more its individual layer of hauling speed is also low more, so screw speed and hauling speed only are provided among each embodiment, the inventory of each layer component are not provided.
Embodiment 1
Three-layer co-extruded machine is produced the thick coextruded film of 0.10mm:
1) extrude: outer raw material mixes low density polyethylene (LDPE) (pressing mass ratio 1:1 mixes) with linear polyethylene; The middle level raw material mixes LLDPE (pressing mass ratio 2:1 mixes) with the linear polyethylene metallocene PE; The internal layer raw material is a polypropylene.Three kinds of raw materials are squeezed into extruder respectively and melt extrude through heating plasticizing, enter the three layers of die head in spiral center again.Three layers of material temperature scope: 160 ℃ ~ 200 ℃ of outer extruder body temperatures, 170 ℃ ~ 200 ℃ of middle level extruder body temperatures, 180 ℃ ~ 210 ℃ of internal layer extruder body temperatures, die head temperature are 190 ℃ ~ 210 ℃.Screw speed is: outer 30 rev/mins, and 40 rev/mins in middle level, 45 rev/mins of internal layers.
2) blown film: when described polymer molten fluid goes out die head, by inflation of three-layer co-extruded blown film unit, be drawn into film again, described blow-up ratio is 1:1.5, and draw speed is 10m/min; Thereby control outer content is 24%, and middle level content is 26%, and internal layer content is 50%.
3) air-cooled, water-cooled shaping: will adopt air-cooled earlier, water-cooled shaping again through the film that step 2 stretches, cooling line height is 0.8m, to crystallisation by cooling;
4) surface treatment, rolling: will handle through the film surface of step 3 cooling, and be rolled into the film volume again, through cutting, be packaged to be described three-layer co-extruded medical plastic uptake composite package film.
Embodiment 2
Three-layer co-extruded machine is produced the thick coextruded film of 0.12mm:
1) extrude: outer raw material mixes low density polyethylene (LDPE) (pressing mass ratio 8:1 mixes) with linear polyethylene; The middle level raw material mixes LLDPE (pressing mass ratio 10:1 mixes) with the linear polyethylene metallocene PE; The internal layer raw material is a polypropylene.Three kinds of raw materials are squeezed into extruder respectively and melt extrude through heating plasticizing, enter the three layers of die head in spiral center again.Three layers of material temperature scope: 170 ℃ ~ 200 ℃ of outer extruder body temperatures, 180 ℃ ~ 200 ℃ of middle level extruder body temperatures, 180 ℃ ~ 210 ℃ of internal layer extruder body temperatures, die head temperature are 200 ℃ ~ 210 ℃.Screw speed is: outer 35 rev/mins, and 50 rev/mins in middle level, 40 rev/mins of internal layers.
2) blown film: when described polymer molten fluid goes out die head, by inflation of three-layer co-extruded blown film unit, be drawn into film again, described blow-up ratio is 1:1.5, and draw speed is 15m/min; Thereby control outer content is 30%, and middle level content is 40%, and internal layer content is 30%.
3) air-cooled, water-cooled shaping: will adopt air-cooled earlier, water-cooled shaping again through the film that step 2 stretches, cooling line height is 1.0m, to crystallisation by cooling;
4) surface treatment, rolling: will handle through the film surface of step 3 cooling, and be rolled into the film volume again, through cutting, be packaged to be described three-layer co-extruded medical plastic uptake composite package film.
Embodiment 3
The five-layer co-squeezing machine is produced the thick co-extrusion PA film of 0.10mm:
1) extrude: five layers of material are divided into: PA/ adhesive/PA/ adhesive/PE(A layer/B layer/C layer/D layer/E layer), the PA of A layer and C layer is the pellet of nylon 6, standby through heating, drying (70 ℃ ~ 90 ℃), the adhesive of B layer and C layer is the import pellet, and E layer PE is low density polyethylene (LDPE); Five kinds of components are squeezed into extruder respectively and melt extrude through heating plasticizing, enter the three layers of die head in spiral center again.Each layer material temperature scope: 200 ℃ ~ 240 ℃ of PA layer extruder body temperatures, 180 ℃ ~ 200 ℃ of adhesive phase extruder body temperatures, 180 ℃ ~ 200 ℃ of PE layer extruder body temperatures.Each layer screw speed: the A layer is 30 rev/mins, and the B layer is 20 rev/mins, and the C layer is 30 rev/mins, and the D layer is 15 rev/mins, and the E layer is 40 rev/mins; Die head temperature: 200 ℃ ~ 210 ℃.Each layer melt flow rate (MFR) is 2 ~ 10kg/10min, and extrusion machine fused mass pressure is 15 ~ 40MPa.
2) blown film: when described polymer molten fluid goes out die head, by inflation of five-layer co-squeezing blown film unit, be drawn into film again, described blow-up ratio is 1:1.8, and draw speed is 16m/min; Thereby controlling five layer components (A layer/B layer/C layer/D layer/E layer) content is respectively: 22%, 15%, 22%, 11%, 30%;
3) air-cooled, water-cooled shaping: the film that will stretch through step 2 is earlier through air-cooled, and again through water-cooled shaping, cooling line height is 0.5m, to crystallisation by cooling;
4) surface treatment, rolling: will be rolled into the film volume again, through cutting, be packaged to be the medical plastic uptake composite package film of described five-layer co-squeezing through the film surface sided corona treatment of step 3 cooling.
Embodiment 4
The five-layer co-squeezing machine is produced the thick co-extrusion PA film of 0.08mm:
1) extrude: five layers of material are divided into: PA/ adhesive/PA/ adhesive/PE(A layer/B layer/C layer/D layer/E layer), the PA of A layer and C layer is the pellet of copolymer nylon, standby through heating, drying (70 ℃ ~ 90 ℃), the adhesive of B layer and C layer is the import pellet, and E layer PE is low density polyethylene (LDPE); Five kinds of components are squeezed into extruder respectively and melt extrude through heating plasticizing, enter the three layers of die head in spiral center again.Each layer material temperature scope: 210 ℃ ~ 240 ℃ of PA layer extruder body temperatures, 170 ℃ ~ 190 ℃ of adhesive phase extruder body temperatures, 180 ℃ ~ 200 ℃ of PE layer extruder body temperatures.Each layer screw speed: the A layer is 25 rev/mins, and the B layer is 20 rev/mins, and the C layer is 20 rev/mins, and the D layer is 15 rev/mins, and the E layer is 50 rev/mins; Die head temperature: 220 ℃ ~ 240 ℃.Each layer melt flow rate (MFR) is 2 ~ 10kg/10min, and extrusion machine fused mass pressure is 15 ~ 40MPa.
2) blown film: when described polymer molten fluid goes out die head, by inflation of five-layer co-squeezing blown film unit, be drawn into film again, described blow-up ratio is 1:1.2, and draw speed is 24m/min; Thereby controlling five layer components (A layer/B layer/C layer/D layer/E layer) content is respectively: 16%, 10%, 14%, 5%, 55%;
3) air-cooled, water-cooled shaping: the film that will stretch through step 2 is earlier through air-cooled, and again through water-cooled shaping, cooling line height is 0.5m, to crystallisation by cooling;
4) surface treatment, rolling: will be rolled into the film volume again, through cutting, be packaged to be the medical plastic uptake composite package film of described five-layer co-squeezing through the film surface sided corona treatment of step 3 cooling.
Embodiment 5
The five-layer co-squeezing machine is produced the thick co-extrusion PA film of 0.10mm:
1) extrude: five layers of material are divided into: PA/ adhesive/PA/ adhesive/PP(A layer/B layer/C layer/D layer/E layer), the PA of A layer and C layer is the pellet of nylon 6, standby through heating, drying (70 ℃ ~ 90 ℃), the adhesive of B layer and C layer is the import pellet, and E layer PP is polypropylene; Five kinds of components are squeezed into extruder respectively and melt extrude through heating plasticizing, enter the three layers of die head in spiral center again.Each layer material temperature scope: 210 ℃ ~ 240 ℃ of PA layer extruder body temperatures, 180 ℃ ~ 200 ℃ of adhesive phase extruder body temperatures, 220 ℃ ~ 240 ℃ of PP layer extruder body temperatures.Each layer screw speed: the A layer is 30 rev/mins, and the B layer is 25 rev/mins, and the C layer is 30 rev/mins, and the D layer is 20 rev/mins, and the E layer is 45 rev/mins; Die head temperature: 220 ℃ ~ 230 ℃.Each layer melt flow rate (MFR) is 2 ~ 10kg/10min, and extrusion machine fused mass pressure is 15 ~ 40MPa.
2) blown film: when described polymer molten fluid goes out die head, by inflation of five-layer co-squeezing blown film unit, be drawn into film again, described blow-up ratio is 1:2.5, and draw speed is 20m/min; Thereby controlling five layer components (A layer/B layer/C layer/D layer/E layer) content is respectively: 20%, 17%, 20%, 13%, 30%;
3) air-cooled, water-cooled shaping: the film that will stretch through step 2 is earlier through air-cooled, and again through water-cooled shaping, cooling line height is 0.5m, to crystallisation by cooling;
4) surface treatment, rolling: will be rolled into the film volume again, through cutting, be packaged to be the medical plastic uptake composite package film of described five-layer co-squeezing through the film surface sided corona treatment of step 3 cooling.
Embodiment 6
The five-layer co-squeezing machine is produced the thick co-extrusion PA film of 0.05mm:
1) extrude: five layers of material are divided into: PA/ adhesive/PA/ adhesive/PP(A layer/B layer/C layer/D layer/E layer), the PA of A layer and C layer is the pellet of copolymer nylon, standby through heating, drying (70 ℃ ~ 90 ℃), the adhesive of B layer and C layer is the import pellet, and E layer PP is polypropylene; Five kinds of components are squeezed into extruder respectively and melt extrude through heating plasticizing, enter the three layers of die head in spiral center again.Each layer material temperature scope: 210 ℃ ~ 240 ℃ of PA layer extruder body temperatures, 180 ℃ ~ 200 ℃ of adhesive phase extruder body temperatures, 220 ℃ ~ 240 ℃ of PP layer extruder body temperatures.Each layer screw speed: the A layer is 25 rev/mins, and the B layer is 15 rev/mins, and the C layer is 25 rev/mins, and the D layer is 15 rev/mins, and the E layer is 35 rev/mins; Die head temperature: 220 ℃ ~ 230 ℃.Each layer melt flow rate (MFR) is 2 ~ 10kg/10min, and extrusion machine fused mass pressure is 15 ~ 40MPa.
2) blown film: when described polymer molten fluid goes out die head, by inflation of five-layer co-squeezing blown film unit, be drawn into film again, described blow-up ratio is 1:2, and draw speed is 30m/min; Thereby controlling five layer components (A layer/B layer/C layer/D layer/E layer) content is respectively: 22%, 13%, 23%, 10%, 32%;
3) air-cooled, water-cooled shaping: the film that will stretch through step 2 is earlier through air-cooled, and again through water-cooled shaping, cooling line height is 0.5m, to crystallisation by cooling;
4) surface treatment, rolling: will be rolled into the film volume again, through cutting, be packaged to be the medical plastic uptake composite package film of described five-layer co-squeezing through the film surface sided corona treatment of step 3 cooling.
More than each embodiment products obtained therefrom to detect data as shown in table 1:
Table 1
By above form as can be known, adopt preparation method of the present invention, the multi-layer co-extruded medical plastic uptake composite package film of preparation is transparent airtight, has good percentage elongation and physical and mechanical properties.
Claims (9)
1. multi-layer co-extruded medical plastic uptake composite package film is characterized in that: it comprises the interior trilamellar membrane of outer, neutralization, and component of each layer and weight percentage are from outside to inside:
Skin is blend 20 ~ 30 mass fractions of low density polyethylene (LDPE) and Linear low-density polyethylene,
The middle level is LLDPE and metallocene low density polyethylene blend 20 ~ 40 mass fractions,
Internal layer is polypropylene 30 ~ 50 mass fractions,
Described cladding material low density polyethylene (LDPE) mixes by weight 1 ~ 8:1 with Linear low-density polyethylene; Middle level material LLDPE mixes by weight 1 ~ 10:1 with metallocene low density polyethylene.
2. multi-layer co-extruded medical plastic uptake composite package film, it is characterized in that: it comprises five layers, is followed successively by from top to bottom:
PA polyamide layer 10 ~ 25 mass fraction,
Adhesive phase 5 ~ 15 mass fractions,
PA polyamide layer 10 ~ 25 mass fraction,
Adhesive phase 5 ~ 15 mass fractions,
Ldpe resin or polypropylene layer 30 ~ 60 mass fractions.
3. multi-layer co-extruded medical plastic uptake composite package film according to claim 1 and 2, it is characterized in that: the melt index of described low density polyethylene (LDPE) is 1.5 ~ 6, and polyacrylic melt index is 2.5 ~ 10, and the melt index of LLDPE is 1.5 ~ 8.
4. multi-layer co-extruded medical plastic uptake composite package film according to claim 2 is characterized in that: described PA polyamide layer is nylon 6 or copolymer nylon, and relative viscosity is 2 ~ 5.5.
5. the preparation method of multi-layer co-extruded medical plastic uptake composite package film according to claim 1 and 2 is characterized in that: described preparation method may further comprise the steps:
1) extrude: each layer raw material delivered to heating and melting becomes polymer melt in three layers or five-layer co-squeezing blown film unit three or five extruders, each each layer of runner component by spiral center die head closes in that the upper layer of mouth mould is stacked then, is combined into the co-extrusion film; Described three layers or five-layer co-squeezing blown film unit all adopt single screw extrusion machine, and screw slenderness ratio is 32:1, and the body temperature of extruder is 160 ~ 240 ℃, and die head temperature is 190 ~ 240 ℃, and screw speed is 15 ~ 50 rev/mins;
2) blown film: when described polymer molten fluid goes out die head, made by three layers or inflation of five-layer co-squeezing blown film unit, be drawn into film again, described blow-up ratio is 1:1.2 ~ 2.5, and draw speed is 10 ~ 30m/min;
3) air-cooled, water-cooled shaping: will adopt water-cooled shaping through the film that step 2 stretches, cooling line height is 0.5 ~ 1.0, the acute cold crystallization of cooling pattern;
4) surface treatment, rolling: will be rolled into the film volume again, through cutting, be packaged to be described multi-layer co-extruded medical plastic uptake composite package film through the film surface sided corona treatment of step 3 cooling.
6. the preparation method of multi-layer co-extruded medical plastic uptake composite package film according to claim 5, it is characterized in that: in the described step 1, when raw material is five layers, described each strata compound melt flow rate (MFR) is 2 ~ 10kg/10min, and the melt pressure of polymer melt in extruder is 15 ~ 40MPa.
7. the preparation method of multi-layer co-extruded medical plastic uptake composite package film according to claim 5 is characterized in that: the body temperature in the described step 1 is 170 ~ 200 ℃.
8. the preparation method of multi-layer co-extruded medical plastic uptake composite package film according to claim 5 is characterized in that: the die head temperature in the described step 1 is 190 ~ 210 ℃.
9. the preparation method of multi-layer co-extruded medical plastic uptake composite package film according to claim 5 is characterized in that: the thickness of the multi-layer co-extruded medical plastic uptake composite package film that described step 4 obtains is 0.05 ~ 0.12mm.
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