CN102218088A - Oral ulcer inunction liquid - Google Patents
Oral ulcer inunction liquid Download PDFInfo
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- CN102218088A CN102218088A CN2011101521676A CN201110152167A CN102218088A CN 102218088 A CN102218088 A CN 102218088A CN 2011101521676 A CN2011101521676 A CN 2011101521676A CN 201110152167 A CN201110152167 A CN 201110152167A CN 102218088 A CN102218088 A CN 102218088A
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- oral ulcer
- liquid
- inunction
- menthol
- salicylic acid
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
An oral ulcer inunction liquid. The invention relates to a medicament, and especially relates to an oral ulcer inunction liquid for treating oral ulcer. A technical scheme of the invention is as follows: 1. a formula proportion of the invention is that, by weight, menthol 5-15, borneol 5-15, dimethyl sulfoxide 8-12, salicylic acid 20-30, glycerin 20-30, 75% alcohol 300-500 and distilled water 10-30; 2. preparation process comprises the steps of: mixing and dissolving menthol, borneol, dimethyl sulfoxide, salicylic acid, glycerin; adding into the 75% alcohol after complete dissolving; mixing uniformly and adding distilled water; shaking well to finish. The present invention has the beneficial effects that: compared with similar paste agent, powder, lozenge and pad pasting for treating oral ulcer, the oral ulcer inunction liquid has faster curative effects, good pain relieving effect, rapid effectiveness after application, and oral ulcer surface can be healed within 3-4d.
Description
Technical field
The present invention relates to a kind of medicine, relate in particular to a kind of oral ulcer for the treatment of oral ulcer and embrocate liquid.
Background technology
Oral ulcer, among the peoplely generally be referred to as " getting angry in the oral cavity " or " aphtha ", be a kind of be the oral mucosa limitation ulcerative lesions of characteristics with outbreak periodically repeatedly, but spontaneous recovery, but, generally be difficult to the short time recovery from illness because ulcer has characteristics such as periodicity, recurrent and self limiting.
The cause of disease of oral ulcer is local wound, psychentonia, food, medicine, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism may play an important role in its generation, development.Treatment is mainly based on topical therapeutic, and severe patient needs whole body therapeutic.Modern medicine thinks that recurrent oral ulceration at first has very confidential relation with immunity.The patient who has shows as immunodeficiency, and the patient who has then shows as autoimmune response, just because various factors, makes the normal immune system of human body, to autologous tissue's antigen, produces the immunity reflection, and causes disorganization and fall ill.
The method of treatment oral ulcer is also varied, mainly contain Western medicine for oral administration, Chinese traditional treatment, food are supported methods such as treating or paste the ulcer subsides, wherein Chinese traditional treatment and dietetic curative effect are slower, Western medicine for oral administration need be according to the cause of disease evolution of ulcer, the effect that ulcer is pasted still is not fully up to expectations, so be badly in need of wanting a kind of better efficacy, makes things convenient for again Therapeutic Method efficiently.
Summary of the invention
According to above deficiency, the invention provides a kind of oral ulcer and embrocate liquid, its better efficacy, analgesic effect is faster.
The technical solution used in the present invention is:
One, formula proportion of the present invention is (weight ratio): menthol 5-15; Borneolum Syntheticum 5-15; Dimethyl sulfoxide 8-12; Salicylic acid 20-30; Glycerol 20-30; 75% ethanol 300-500, distilled water 10-30.
Preferred version is menthol 10g; Borneolum Syntheticum 10g; Dimethyl sulfoxide 10g; Salicylic acid 25g; Glycerol 25g; 75% ethanol 400g, distilled water 20g.
Two, preparation process is: earlier with menthol, Borneolum Syntheticum, dimethyl sulfoxide, salicylic acid, glycerol mixed dissolution, treat that adding distil water shakes up and gets final product behind the mix homogeneously in the ethanol of fully dissolving back adding 75%.
The medicinal function of each constituent is as follows among the present invention:
Menthol: aromatic drug, remedium corrigens and carminative.Can be used for skin or mucosa and produce that refrigerant sense is not suitable for to alleviate, pain.
Borneolum Syntheticum: property is cold and cool partially, is the product of waking up the patient from unconsciousness by clearing away heat, and this product bitter cold has clearing away heat to alleviate pain, the logical all keys of detumescence, and the merit of the stagnated fire of loosing is usually used in treating the sore throat aphtha, and skin infection swells and ache, and does not hold back after bursting.
Dimethyl sulfoxide: anti-inflammatory analgetic is arranged, diuresis, " catholicon " also is described as in effects such as calmness, and the active component of Chang Zuowei analgesic drug product makes an addition among the medicine.In medicine production, be widely used as solvent and reaction reagent, be described as " alembroth "
Salicylic acid: salicylic acid can dissolve the formation shape material between cutin, horny layer is produced come off, and gathers blocked up horny layer so can remove, and enhances metabolism.The slough that can help the desurfacing iuntercellular to stop up is revised abnormal cell detachment.
Glycerol: a kind of sweet, colourless syrupy liq of distinguishing the flavor of.Add glycerol in the food, normally, make food smooth good to eat as a kind of sweeting agent and the material of preserving moisture.Can increase the moisture in tissue, the cell, an amount of glycerol has protective effect to normal cell tissue.
Ethanol and distilled water: as lytic agent and diluent.
The invention has the beneficial effects as follows: compare with unguentum, powder, buccal tablet, the pad pasting of similar treatment oral ulcer, this oral ulcer liquid curative effect is faster, and analgesic effect is better, takes effect at once after embrocating, and oral ulcer surface healed in 3～4 days.
The specific embodiment
Further be illustrated below in conjunction with the specific embodiment:
Embodiment: the configuration oral ulcer is embrocated liquid, the selection material menthol 10g of elder generation, Borneolum Syntheticum 10g, dimethyl sulfoxide 10g, salicylic acid 25g, glycerol 25g mixed dissolution, treat that fully the dissolving back adds in 75% ethanol of 400g, add the 20g distilled water behind the mix homogeneously and shake up and get final product.
Claims (3)
1. an oral ulcer is embrocated liquid, and feature is that formula proportion of the present invention is (weight ratio): menthol 5-15; Borneolum Syntheticum 5-15; Dimethyl sulfoxide 8-12; Salicylic acid 20-30; Glycerol 20-30; 75% ethanol 300-500, distilled water 10-30.
2. a kind of oral ulcer according to claim 1 is embrocated liquid, and feature is that the preferred version of formula proportion (weight ratio) is menthol 10g; Borneolum Syntheticum 10g; Dimethyl sulfoxide 10g; Salicylic acid 25g; Glycerol 25g; 75% ethanol 400g, distilled water 20g.
3. a kind of oral ulcer according to claim 1 is embrocated liquid, feature is that preparation process is: earlier with menthol, Borneolum Syntheticum, dimethyl sulfoxide, salicylic acid, glycerol mixed dissolution, treat that adding distil water shakes up and gets final product behind the mix homogeneously in the ethanol of fully dissolving back adding 75%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011101521676A CN102218088A (en) | 2011-06-08 | 2011-06-08 | Oral ulcer inunction liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011101521676A CN102218088A (en) | 2011-06-08 | 2011-06-08 | Oral ulcer inunction liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102218088A true CN102218088A (en) | 2011-10-19 |
Family
ID=44774959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011101521676A Pending CN102218088A (en) | 2011-06-08 | 2011-06-08 | Oral ulcer inunction liquid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102218088A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2518826A (en) * | 2013-09-27 | 2015-04-08 | Thanasis Athanasiou | Composition |
| GB2533669A (en) * | 2014-12-23 | 2016-06-29 | Innovate Pharmaceuticals Ltd | Salicylate compound composition |
| CN105963248A (en) * | 2016-06-15 | 2016-09-28 | 中南大学湘雅二医院 | Gargle for preventing and treating mouth mucositis caused by chemoradiotherapy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1147373A (en) * | 1996-07-25 | 1997-04-16 | 郭晓辉 | Refreshing liquid |
| CN1656896A (en) * | 2004-02-20 | 2005-08-24 | 山东省莱芜市新宇生物科技有限公司 | Rare earth disinfectant bactericidal agent |
-
2011
- 2011-06-08 CN CN2011101521676A patent/CN102218088A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1147373A (en) * | 1996-07-25 | 1997-04-16 | 郭晓辉 | Refreshing liquid |
| CN1656896A (en) * | 2004-02-20 | 2005-08-24 | 山东省莱芜市新宇生物科技有限公司 | Rare earth disinfectant bactericidal agent |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2518826A (en) * | 2013-09-27 | 2015-04-08 | Thanasis Athanasiou | Composition |
| GB2533669A (en) * | 2014-12-23 | 2016-06-29 | Innovate Pharmaceuticals Ltd | Salicylate compound composition |
| GB2533669B (en) * | 2014-12-23 | 2016-12-14 | Innovate Pharmaceuticals Ltd | Salicylate compound composition |
| US11129837B2 (en) | 2014-12-23 | 2021-09-28 | Innovate Pharmaceuticals Limited | Salicylate compound composition |
| CN105963248A (en) * | 2016-06-15 | 2016-09-28 | 中南大学湘雅二医院 | Gargle for preventing and treating mouth mucositis caused by chemoradiotherapy |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20111019 |