CN102102135A - Method for producing sucrose for injection - Google Patents
Method for producing sucrose for injection Download PDFInfo
- Publication number
- CN102102135A CN102102135A CN2010105736117A CN201010573611A CN102102135A CN 102102135 A CN102102135 A CN 102102135A CN 2010105736117 A CN2010105736117 A CN 2010105736117A CN 201010573611 A CN201010573611 A CN 201010573611A CN 102102135 A CN102102135 A CN 102102135A
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- syrup
- production method
- injection stage
- clear juice
- sugar
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Abstract
The invention discloses a method for producing sucrose for injection, which comprises: dissolving a raw material sugar to produce sugar water; treating the sugar water to obtain clear juice; evaporating the clear juice to obtain sugar syrup; boiling the sugar syrup; and purging, drying and packing. By adopting the steps of the technical scheme used in the invention, the grain size and uniformity of the produced sucrose for injection are both in accordance with the requirements of standards.
Description
Technical field
The present invention relates to sucrose processing purifying technique, particularly a kind of production method of injection stage sucrose.
Background technology
Injection stage sucrose must be strengthened the decolouring and the defecation effect of liquid glucose in process of production as far as possible in whole process, the coloring matter in the liquid glucose and other non-sugared composition are minimized, and carried out the control of microbial limit.
Summary of the invention
The purpose of this invention is to provide and a kind of raw material sucrose is processed into the method for injection stage sucrose, technical scheme is: a kind of injection stage sucrose production method may further comprise the steps:
A, raw material sugar dissolving generated the step of syrup;
B, syrup handled the step that produces clear juice; Described processing is to adopt medicinal active carbon and ion exchange resin to handle;
C, clear juice evaporated produce syrupy step;
D, syrup is boiled the step that sugar produces massecuite;
E, massecuite carried out the step of purging, drying and dress bag.
Further, in above-mentioned a kind of injection stage sucrose production method: in described step B: it is to adopt following steps that described removal impurity is handled:
B1 pumps into syrup in the jar that gac is housed with pump;
B2 is pumped in the jar that ion exchange resin is housed with pump syrup extraction through the intact impurity of charcoal absorption in the jar of gac is housed;
The syrup that B3 handled through anion and cation exchange resin in the jar of ion exchange resin is housed with pump divides the clear juice after removing as far as possible to extract out aglucone;
The clear juice of B4, extraction is removed the impurity treatment step through finishing behind the membrane filtration.
Be to adopt whizzer that molasses are isolating in described step e.
Concrete, in above-mentioned a kind of injection stage sucrose production method: in the steps A: raw material sugar solvent temperature is: 85 ± 2 °, the concentration of ordinary dissolution of raw material sugar is 29-31Be.Described clear juice colourity is that 10 ° of St are following, turbidity is below 4 °.Among the described step C: the concentration of evaporating sugar-molasses syrup is 66-68 ° of Bx, and colourity is 8 ° below the St.Among the described step D, it is more than the AP98.3 that syrup is boiled into concentration.In the described step e, dress bag temperature is controlled at below 55 °.
By adopting the step of technical solution of the present invention, the injection utmost point sucrose sand grains size and the evening ratio of generation can both the conformance with standard requirements.
Description of drawings
Accompanying drawing 1 is the embodiment of the invention 1 process flow sheet.
Embodiment:
As shown in Figure 1, present embodiment is the logical injection stage sucrose complete processing that is processed into of a kind of raw material sugar with sucrose.As shown in the figure, may further comprise the steps:
A, raw material sugar dissolving generated the step of syrup; At this moment, raw material sugar solvent temperature is: 85 ± 2 °, the concentration of ordinary dissolution of raw material sugar is 29-31Be.
B, syrup is removed the step that impurity handle to produce clear juice; Described processing is to adopt medicinal active carbon and ion exchange resin to handle; Adopt following steps to finish the step of removing impurity:
B1 pumps into syrup in the jar that gac is housed with pump;
B2 is pumped in the jar that ion exchange resin is housed with pump syrup extraction through the intact impurity of charcoal absorption in the jar of gac is housed;
The syrup that B3 handled through anion and cation exchange resin in the jar of ion exchange resin is housed with pump divides the clear juice after removing as far as possible to extract out aglucone;
The clear juice of B4, extraction is removed the impurity treatment step through finishing behind the membrane filtration, and microorganism is filtered.
At this moment, clear juice colourity is that 10 ° of St are following, turbidity is below 4 °.
C, clear juice evaporated produce syrupy step; The concentration of evaporating sugar-molasses syrup is 66-68 ° of Bx, and colourity is 8 ° below the St.
D, be that syrup more than the AP98.3 boils into massecuite with concentration;
E, carry out the step of purging, drying and dress bag, the temperature of dress bag is controlled at below 55 °, and purging is to adopt whizzer that molasses are isolating.
By above step, the injection stage sucrose of generation is that " sucrose physics and chemistry, sense organ, the sanitary index of second defined of Chinese pharmacopoeia version in 2010 are to satisfy the quality product requirement in strict nearly target level of product quality execution.
Above ° Bx refers to look in the solution unit of dissolved solids content; ° St is that Si Danmo (abbreviation of Stammer) is the unit of colourity in the sugar manufacturing industry term, and the unit degree of being of turbidity (°), the colloidal particle existence causes the numerical value of scattering of light degree because opacity is in the syrup.Turbidity once when containing 1mg silicon-dioxide caused muddy degree represent or directly use " degree " expression with mg/L as an opacity unit.
Claims (8)
1. injection stage sucrose production method is characterized in that: may further comprise the steps:
A, raw material sugar dissolving generated the step of syrup;
B, syrup is removed the step that impurity handle to produce clear juice;
C, clear juice evaporated produce syrupy step;
D, syrup is boiled the step that sugar produces massecuite;
E, carry out the step of purging, drying and dress bag.
2. a kind of injection stage sucrose production method according to claim 1 is characterized in that: in described step B: it is to adopt following steps that described removal impurity is handled:
B1 pumps into syrup in the jar that gac is housed with pump;
B2 is pumped in the jar that ion exchange resin is housed with pump syrup extraction through the intact impurity of charcoal absorption in the jar of gac is housed;
The syrup that B3 handled through anion and cation exchange resin in the jar of ion exchange resin is housed with pump divides the clear juice after removing as far as possible to extract out aglucone;
The clear juice of B4, extraction is removed the impurity treatment step through finishing behind the membrane filtration.
3. a kind of injection stage sucrose production method according to claim 1 is characterized in that: be to adopt whizzer that molasses are isolating in described step e.
4. a kind of injection stage sucrose production method according to claim 1 is characterized in that: in the steps A: raw material sugar solvent temperature is: 85 ± 2 °, the concentration of ordinary dissolution of raw material sugar is 29-31Be.
5. a kind of injection stage sucrose production method according to claim 1 is characterized in that: described clear juice colourity is that 10 ° of St are following, turbidity is below 4 °.
6. a kind of injection stage sucrose production method according to claim 1 is characterized in that: among the described step C: the concentration of evaporating sugar-molasses syrup is 66-68 ° of Bx, and colourity is 8 ° below the St.
7. a kind of injection stage sucrose production method according to claim 1 is characterized in that: among the described step D, it is more than the AP98.3 that syrup is boiled into concentration.
8. according to the described a kind of injection stage sucrose production method of arbitrary claim in the claim 1 to 7, it is characterized in that: in the described step e, dress bag temperature is controlled at below 55 °.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105736117A CN102102135A (en) | 2010-12-03 | 2010-12-03 | Method for producing sucrose for injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105736117A CN102102135A (en) | 2010-12-03 | 2010-12-03 | Method for producing sucrose for injection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102102135A true CN102102135A (en) | 2011-06-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105736117A Pending CN102102135A (en) | 2010-12-03 | 2010-12-03 | Method for producing sucrose for injection |
Country Status (1)
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| CN (1) | CN102102135A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103276115A (en) * | 2013-05-11 | 2013-09-04 | 湖南湘易康制药有限公司 | Production technology of medicinal sucrose |
| CN105603129A (en) * | 2015-03-30 | 2016-05-25 | 河南工业大学 | Preparation method of healthy and nutritional sugar |
| CN106191324A (en) * | 2016-08-31 | 2016-12-07 | 广西农垦糖业集团昌菱制糖有限公司 | Boil the method that sugar produces white sugar |
| CN106799171A (en) * | 2015-11-26 | 2017-06-06 | 利乐拉瓦尔集团及财务有限公司 | A kind of retort, continuous sugar dissolver and method |
| CN116143850A (en) * | 2022-12-22 | 2023-05-23 | 中粮崇左糖业有限公司 | Injection-grade sucrose, preparation method and application thereof |
| CN116217637A (en) * | 2022-12-22 | 2023-06-06 | 中粮崇左糖业有限公司 | Injection-grade sucrose, preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0372900A (en) * | 1989-08-09 | 1991-03-28 | Fuji Seito Kk | Method for purifying sucrose solution and treating equipment therefor |
| CN1326003A (en) * | 2000-05-25 | 2001-12-12 | 李成义 | Medical cane sugar and its preparing process |
| CN101508707A (en) * | 2009-03-25 | 2009-08-19 | 湖南尔康制药有限公司 | Production process for medicinal sucrose |
-
2010
- 2010-12-03 CN CN2010105736117A patent/CN102102135A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0372900A (en) * | 1989-08-09 | 1991-03-28 | Fuji Seito Kk | Method for purifying sucrose solution and treating equipment therefor |
| CN1326003A (en) * | 2000-05-25 | 2001-12-12 | 李成义 | Medical cane sugar and its preparing process |
| CN101508707A (en) * | 2009-03-25 | 2009-08-19 | 湖南尔康制药有限公司 | Production process for medicinal sucrose |
Non-Patent Citations (4)
| Title |
|---|
| 广东省糖纸食品工业公司: "《糖膏煮炼与助晶》", 30 April 1983, article "三、煮糖及分段煮糖的机理", pages: 32-33 * |
| 广东轻工业学校等: "《甘蔗制糖工艺学》", 31 August 1982, article ""第六章 分蜜与干燥""第一节 糖膏的分蜜"", pages: 359 * |
| 朱文效: "转化糖注射液制备方法的研究", 《药学通报》, vol. 10, no. 4, 31 December 1964 (1964-12-31), pages 170 - 172 * |
| 杨瑞虹: "《药物制剂技术与设备》", 31 August 2010, article "第六章第一节"注射剂概述"源"，", pages: 90-91 * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103276115A (en) * | 2013-05-11 | 2013-09-04 | 湖南湘易康制药有限公司 | Production technology of medicinal sucrose |
| CN103276115B (en) * | 2013-05-11 | 2014-10-01 | 湖南湘易康制药有限公司 | Production technology of medicinal sucrose |
| CN105603129A (en) * | 2015-03-30 | 2016-05-25 | 河南工业大学 | Preparation method of healthy and nutritional sugar |
| CN106799171A (en) * | 2015-11-26 | 2017-06-06 | 利乐拉瓦尔集团及财务有限公司 | A kind of retort, continuous sugar dissolver and method |
| CN106191324A (en) * | 2016-08-31 | 2016-12-07 | 广西农垦糖业集团昌菱制糖有限公司 | Boil the method that sugar produces white sugar |
| CN116143850A (en) * | 2022-12-22 | 2023-05-23 | 中粮崇左糖业有限公司 | Injection-grade sucrose, preparation method and application thereof |
| CN116217637A (en) * | 2022-12-22 | 2023-06-06 | 中粮崇左糖业有限公司 | Injection-grade sucrose, preparation method and application thereof |
| CN116217637B (en) * | 2022-12-22 | 2023-10-24 | 中粮崇左糖业有限公司 | Injection-grade sucrose, preparation method and application thereof |
| CN116143850B (en) * | 2022-12-22 | 2023-12-15 | 中粮崇左糖业有限公司 | Injection-grade sucrose, preparation method and application thereof |
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Application publication date: 20110622 |