CN102100592A - Alginate wound dress material, manufacturing method and manufacturing device thereof - Google Patents
Alginate wound dress material, manufacturing method and manufacturing device thereof Download PDFInfo
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- CN102100592A CN102100592A CN2009102659563A CN200910265956A CN102100592A CN 102100592 A CN102100592 A CN 102100592A CN 2009102659563 A CN2009102659563 A CN 2009102659563A CN 200910265956 A CN200910265956 A CN 200910265956A CN 102100592 A CN102100592 A CN 102100592A
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Abstract
The invention discloses an alginate wound dress material, a manufacturing method and a manufacturing device thereof. The wound dress material contains a first fiber layer consisting of a plurality of mutually bonded first fibers and a second fiber layer consisting of a plurality of mutually bonded second fibers, wherein both the first and second fibers are made of alginate. The first fibers are parallel, and the extending direction of the first fibers is roughly parallel to a first direction. The second fibers are parallel, and the extending direction of the second fibers is roughly parallel to a second direction; and the first direction is not parallel to the second direction. The second fiber layer is stacked on the first fiber layer, and the second fibers are bonded with the first fibers. The lengths of the first fibers and the second fibers are proper so that the breaking strength of the wound dress material is more than about 1.5 kilograms force.
Description
Technical field
The relevant a kind of wound of the present invention is applied material, and particularly relevant a kind of alginate wound is applied material.
Background technology
When handling wound, it is generally acknowledged to keep the wound drying can provide wound healing preferable environment in the past, made the easier healing of wound.Therefore in the traditional treatment mode, the soil that mainly uses gauze to avoid wound to be subjected in the external environment infects, even keeps the dry and cleaning of wound.But in this therapy, wound and the mutually glutinous situation of wound dressing take place in regular meeting, when causing removing wound dressing, are stained with the wound that bonds to firm healing and cause the secondary to wound to injure.
In recent years, scientist establishes and have the effect that promotes wound healing under moist environment.In the secreted liquid of wound, also find to exist most growth factors (growth factor) that promote wound healings.Therefore establish the scientific evidence that under moist environment, can promote wound healing, set up the notion of closed coated material simultaneously.According to this notion, develop several wounds and apply material, apply material as the wound of PU film, chitin (chitin)/spherical chitosan (chitosan, or title chitin), collagen protein (collagen) or alginate materials such as (alginate).
The raw material of alginate mainly is from the Sargassum polysaccharide that is extracted in the natural seaweed.Alginate wound is in the market applied material and is mainly contained adhesive-bonded fabric, film and spongy body forms such as (sponge).For example the Kaltostat commodity of Britain BritCair company are the deposited material of wound of adhesive-bonded fabric type.
Yet the alginate wound of above-mentioned adhesive-bonded fabric form is applied material and is existed shortcoming.For instance, when removing wound when applying material, the doctor need carry out the wiping cleaning to wound residual gel and wound fluid with normal saline solution.The alginate wound of adhesive-bonded fabric form is applied material is easy to generate fracture when cleaning situation.On the other hand, the alginate fiber of short fiber comes off easily on the adhesive-bonded fabric, is stained with to stick on wound and form short flannel, causes wound to be difficult for healing.
In view of this, need a kind of new alginate wound to apply material, it can be avoided the alginate wound to apply the material fracture when removal and form problem such as short flannel on wound, to promote wound healing, the convenient use.
Summary of the invention
The wound that the objective of the invention is to propose a kind of new alginate is applied material, and the alginate wound that can solve traditional adhesive-bonded fabric type is applied problems such as material short flannel and fracture.Traditional alginate wound is applied material from wound during removal, can produce fracture or is stained with glutinous wound and forms the reason of problems such as short flannel, mainly is because traditional alginate wound is applied due to the undercapacity of material.
In view of this, the present invention proposes a kind of new wound and applies material, and it mainly comprises the formed long fibre of alginate.By the length of fiber and the arrangement mode of fiber, improve intensity, particularly fracture strength that wound is applied material.
According to an aspect of the present invention, wound is applied material and is comprised two fibre layers at least, first fibrous layer is mutually agglutinating first fibrous by several, and second fibrous layer is second fibrous by several mutual gluings, and wherein the material of first fiber and second fiber is alginate.Alginate can be calcium alginate, alginic acid barium, alginic acid copper, alginic acid zinc, alginic acid silver or alginic acid ferrum.
Wound is applied the arrangement mode of first and second fibers of material, and the fracture strength that makes wound apply material improves.Specifically, first fiber in first fibrous layer side by side and extend and be roughly parallel to first direction.Second fiber in second fibrous layer side by side and extend and be roughly parallel to second direction, wherein first direction is not parallel to second direction.In an optional embodiment, first direction and second direction are orthogonal.
Second fibrous layer is stacked on first fibrous layer, and second fiber coheres first fiber.In an embodiment of the present invention, first fiber and second fiber only cohere and do not weave, and meaning i.e. first fiber and the winding mutually of second fiber.
First fiber and second fiber are long fine.Specifically, the length of first fiber and second fiber is suitable length, makes wound apply the fracture strength of material greater than 1.5 kgfs.According to optional embodiment, the fracture strength that wound is applied material is that 100 kgfs are between about 109 kgfs.In embodiments of the present invention, above-mentioned suitable length is meant that the length of first fiber and second fiber is respectively between about 5 centimetres to 20 centimetres.
Hence one can see that, wound is applied material and is had the long first and second fine fibers, and by the arrangement mode of first fiber and second fiber, make wound apply the fracture strength of material all directions, especially the fracture strength along the bearing of trend of first fiber and second fiber is improved.
The manufacture method that the present invention provides a kind of wound to apply material on the other hand, the wound that has the alginate of high fracture strength in order to manufacturing is applied material.First step that wound is applied the manufacture method of material is to carry out a wet type spinning process, to form at least one alginate fiber.Then, twine the alginate fiber in plate, to form several first fibers on a surface of plate.Lip-deep first fiber at plate is arranged side by side mutually, and roughly extension is parallel to first direction.
Then, twine the alginate fiber once more on plate, to form several second fiber stack on first fiber on the plate.Wherein, second fiber is arranged side by side mutually, and roughly extension is parallel to second direction, the not parallel first direction of second direction.
Between the step of twice winding alginate fiber, rotatable plate.By this, the front and back bearing of trend that is wound in the alginate fiber on the plate for twice then is not parallel to each other.Specifically, the anglec of rotation of plate is the angle of cut between first direction and the second direction.
In an embodiment of the present invention, after carrying out the step of twining the alginate fiber, for example twine for the first time after the step of alginate fiber or after twining the step of alginate fiber once again, can spray the surface of the alginate fiber of sodium ion aqueous solution after twining, make the surface of alginate fiber omit micro dissolution or softening.After treating its dry tack free, the alginate fiber of winding can cohere mutually.Thus, first fiber that is wound on the plate can cohere mutually, and second fiber also can cohere mutually.Alternatively, first fiber and second fiber also can cohere mutually.
In a plurality of embodiment of the present invention, alginate can randomly be calcium alginate, alginic acid barium, alginic acid copper, alginic acid zinc, alginic acid silver or alginic acid ferrum.
In an embodiment of the present invention, the sodium ion aqueous solution is a sodium-chloride water solution, and the concentration of its sodium chloride can be adjusted according to circumstances.In one embodiment of this invention, the concentration expressed in percentage by weight of the sodium chloride in the sodium ion aqueous solution is between about 1% to about 15%.
According to optional embodiment, after the step of carrying out the wet type spinning process, can carry out drafting process, it is to use drawing rollers drawing-off alginate fiber, to adjust the thread breakage intensity of alginate fiber.
Another aspect of the invention provides a kind of wound to apply the material producing device, applies material in order to make the alginate wound.Wound is applied the material producing device and is comprised and batch device, and it is in order to batch fiber.Batching utensil has the rotating shaft of a connection motor, and rotating shaft is arranged on the pedestal.The locking of one plate is in rotating shaft.By the driving of motor, make that plate is that rotate with respect to pedestal at the center with the rotating shaft, and then fiber roll is taken on the plate.
Wound is applied the material producing device and is had a reciprocating apparatus, and it is arranged on and batches before the device, with so that fiber distribute onboard fifty-fifty.Reciprocating apparatus has a through wires hole and passes for fiber.The reciprocating apparatus pedestal that is slidingly connected reciprocatingly slides in order to the axial path that is parallel to rotating shaft along.Thus, when fiber roll was got onboard, fiber was driven by reciprocating apparatus and moves along the direction of principal axis of rotating shaft, and then on average batches on plate.
Wound is applied the material producing device and is had a tension regulator, and it is arranged on and batches before the device.Tension regulator connects fiber, and the tension force in order to fiber in the regulation and control coiling process makes the tension force that batches the fiber of locating at the surface of plate or the edge of plate etc. keep stable.Be slidingly connected pedestal and couple rotating shaft of tension regulator.When plate rotated, tension regulator slided because of rotating shaft drives, and then changed the relative position between itself and the plate.By changing the relative position between tension regulator and the plate, with the tension force of the fiber between retaining plate and the tension regulator.
In optional embodiment, the length of chute is less than the twice of rotating shaft to the distance at the edge of plate.
According to another optional embodiment, tension regulator couples rotating shaft, reciprocatingly slides along chute driven by rotating shaft.
The another kind of optional embodiment that wound is applied the producing device of material has also comprised at least one cam, is connected in the mentioned strain actuator.Another optional embodiment that wound is applied the producing device of material has also comprised at least one banded structure, is connected in rotating shaft.Another embodiment that wound is applied the producing device of material also comprises anchor clamps, is connected in rotating shaft, in order to lock or to unclamp this plate
The embodiment that another kind of optional wound is applied the producing device of material also comprises reciprocating apparatus, and this pedestal that is slidingly connected is in order to connect this fiber and to reciprocatingly slide along an axial path that is parallel to this rotating shaft.In one embodiment, above-mentioned reciprocating apparatus comprises hole, screw rod and actuator.Pedestal is run through in above-mentioned hole; Screw rod passes this hole; And actuator makes an end of this screw rod change to the spacing between this hole in order to promote this screw rod.In another optional embodiment, reciprocating apparatus also comprises through wires hole, is positioned on this screw rod, passes for this fiber.
Comprehensively above-mentioned, the present invention proposes a kind of wound of alginate and applies the deposited material producing device of material, its manufacture method and wound.Wound is applied material and is had formed first and second fibers of alginate, and two fibers extend different directions respectively.By the arrangement mode and the length of first fiber and second fiber, the fracture strength that makes wound apply material is improved.
Description of drawings
For above and other objects of the present invention, feature, advantage and embodiment can be become apparent, below in conjunction with accompanying drawing preferred embodiment of the present invention is described, wherein:
Figure 1A illustrates the sketch map that applies material according to the wound of one embodiment of the invention.
Figure 1B is the photo that the wound of one embodiment of the invention is applied material.
Fig. 2 illustrates the flow chart that applies the manufacture method of material according to the wound of another embodiment of the present invention.
Fig. 3 A illustrates the operation sketch map that applies material according to the wound of another embodiment of the present invention respectively to Fig. 3 F.
Fig. 4 illustrates the front elevational schematic of applying the material producing device according to the wound of one embodiment of the invention.
The wound that Fig. 5 A and Fig. 5 B illustrate Fig. 4 is respectively applied the different operating states of material producing device.
Fig. 6 A to Fig. 6 C illustrates the schematic rear view of the deposited material producing device of wound of different embodiments of the invention respectively.
Fig. 7 is the part enlarged diagram that illustrates the deposited material producing device of wound of Fig. 4.
Fig. 8 A and Fig. 8 B are the profile along the hatching line 8 of Fig. 4, and it represents the different operating states of reciprocating apparatus respectively.
The specific embodiment
Please refer to Figure 1A and Figure 1B, Figure 1A illustrates the sketch map that applies material 100 according to the wound of one embodiment of the invention, and Figure 1B is the photo that the wound of one embodiment of the invention is applied material 100.
The wound that embodiments of the invention proposed is applied material 100, it mainly comprises the formed fiber of alginate, by the length of fiber and the arrangement mode of fiber, improve wound and apply the fracture strength (breakingstrength) of material 100, apply material from wound during removal with the alginate wound of avoiding traditional adhesive-bonded fabric type, institute produces to rupture or be stained with and sticks wound and form problem such as short flannel.
Herein, fracture strength is meant when wound is applied the material fracture, puts on the power on the deposited material of wound, and employed unit is kgf (kgf).In the following embodiments, utilize the standard A STM D3822-2007 of American Society Testing and Materials (Standard Test Method for Tensile Properties of Single Textile Fibers) to measure the fracture strength that wound is applied material 100.
Wound is applied material 100 and is comprised two fibre layers at least, and it is respectively first fibrous layer 110 and second fibrous layer 120.Fiber in the two fibre layers is the long fiber of length.By the length and the arrangement mode of fiber in first fibrous layer 110 and second fibrous layer 120, the fracture strength that makes wound apply material 100 improves.Deposited material 100 each assemblies of wound and characteristic thereof are described in detail as follows with that.
First fibrous layer 110 is made up of several mutual agglutinating first fibers 112.The material of first fiber 112 is an alginate.First fiber 112 is arranged side by side each other, and extends and to be roughly parallel to same direction, hereinafter referred to as first direction 130.
Second fibrous layer 120 is stacked on first fibrous layer 110.Second fibrous layer 120 is made up of second fiber 122 of several mutual gluings.The material of second fiber 122 also is an alginate.Second fiber 122 is arranged side by side each other, and extends and to be roughly parallel to same direction, and hereinafter referred to as second direction 132, wherein first direction 130 is not parallel to second direction 132.
In an embodiment of the present invention, when second fibrous layer 120 was stacked on first fibrous layer 110, second fiber 122 was to cohere on first fiber 112 with smooth kenel.In other words, first fiber 112 and second fiber 122 only cohere and do not weave, and meaning i.e. first fiber 112 and the winding mutually of second fiber 122.
In an embodiment of the present invention, first fiber 112 and second fiber 122 all cohere mutually, use to promote the fracture strength that wound is applied material 100.When making, can be at the fiber of in type alginate surface sprinkling sodium ion aqueous solution as first fiber 112, make slightly micro dissolution or softening of its surface, and produce mucus, to bind the wantonly two first adjacent fibers 112.After treating the mucus drying, first fiber 112 just can cohere mutually.Second fiber 122 also can cohere mutually by said method.Further, can again second fibrous layer 120 be stacked on first fibrous layer 110 at the surface sprinkling sodium ion aqueous solution of first fibrous layer 110.By this, first fiber 112 just can cohere with second fiber 122.
Sodium ion aqueous solution 320 can be the aqueous solution that comprises sodium chloride, and the concentration of the sodium chloride in the aqueous solution can be adjusted according to circumstances.In one embodiment of this invention, the concentration expressed in percentage by weight of the sodium chloride in the sodium ion aqueous solution is between about 1% to about 15%, for example about 1,, 3,4,5,, 7,8,9,10,11,12,13,14 or 15%.In optional embodiment of the present invention, the concentration expressed in percentage by weight of sodium chloride is about 10%.For instance, in preparation hereinafter during the described embodiment of the 1st form, just utilized concentration expressed in percentage by weight to be about 10% sodium-chloride water solution.
The fracture strength of utilizing existing wet type spinning bound water to copy the deposited material of the prepared sodium alginate wound of short fiber adhesive-bonded fabric technology is about 1.493kgf.This fracture strength often is not enough to prevaricate applied force when removing wound and apply material, thereby causes applying problems such as material fracture and short flannel formation.Therefore, according to principle of the present invention and spirit, the length long enough of first fiber 112 and second fiber 122 is so that wound is applied the fracture strength of material 100 greater than 1.5 kgfs.
According to the embodiment of the invention, first fiber 112 and second fiber 122 are long fine, and its length is all greater than about 1 centimetre.In this kind situation, wound is applied the fracture strength of material 100 greater than 1.5 kgfs.
Well known, in a suitable scope, the length of fiber is long more, and the line strength of fiber is also bigger.Line strength described herein is meant the tension force of fiber.The line strength of first fiber 112 and second fiber 122 is big more, and the fracture strength that wound is applied material 100 is big more.
In an embodiment of the present invention, be to select three groups of wounds to apply material 100 with length of different first fibers 112 and second fiber 122, carry out the fracture strength test.Three form and hinder to apply material 100 and all carry out fracture strength with SMI and identical draw speed and test.The gained result is shown in the 1st form.The length of first fiber 112 and second fiber 122 is enough to make wound to apply the fracture strength of material 100 between being about 107 kgfs between about 109 kgfs.
| The length of first fiber (unit: centimetre) | The length of second fiber (unit: centimetre) | Fracture strength (unit: kgf) |
| 5 | 7 | 108.339 |
| 10 | 12 | 107.773 |
| 15 | 20 | 108.813 |
The 1st form
Therefore, according to a plurality of embodiment, the length long enough of first fiber 112 and second fiber 122 is that about 100 kgfs arrive between about 109 kgfs for example about 100,101,102,103,104,105,106,107,108 or 109 kgfs so that wound is applied the fracture strength of material 100.
By the listed embodiment of the 1st form as can be known, desire to reach above-mentioned fracture strength, the length of first fiber 112 and second fiber 122 is respectively between about 5 centimetres to about 20 centimetres, for example about 5,6,7,8,9,10,11,12,13,14,15,16,17,18,19 or 20 centimetres.
In addition, in the described embodiment of the 1st form, the length of first fiber 112 approximates or is slightly less than the width that wound is applied material 100, and the length of second fiber 122 approximates or be slightly less than the length that wound is applied material 100.Certainly, in other embodiment of the present invention, also can use this kind configuration mode.
The bearing of trend of first fiber 112 is parallel to 122 extensions of first direction 130, the second fibers and is parallel to second direction 132, two directions and is not parallel to each other.Change speech, between first direction 130 and the second direction 132 angle is arranged, the angle angle is spent between 180 degree for example about 5,10,15,20,25,30,35,40,45,50,55,60,65,70,75,80,85,90,95,100,105,110,115,120,125,130,135,140,145,150,155,160,165,170,175 or 180 degree between 0.According to optional embodiment of the present invention, first direction 130 is approximately perpendicular to second direction 132.For instance, in each embodiment described in the 1st form, first direction 130 is approximately perpendicular to second direction 132.
Hence one can see that, and wound is applied length and the arrangement mode of material 100 by its first fiber 112 and second fiber 122, makes wound apply the fracture strength of material 100 all directions, and especially the fracture strength along first direction 130 and second direction 132 is improved.
Note that in an embodiment of the present invention, apply material 100 as an illustration though propose to have the wound of two fibre layers, however in fact wound apply the fibrolaminar number of plies that material 100 can have can be two-layer more than, for example 3,4,5 layers or more multi-layered.The bearing of trend of the fiber of the bearing of trend of the fiber in its each layer fibrous layer in can not parallel other fibrous layer.
Fig. 2 illustrates the flow chart that applies the manufacture method 200 of material 100 according to the wound of one embodiment of the invention.Fig. 3 A illustrates the operation sketch map that applies material 100 according to the wound of one embodiment of the invention respectively to Fig. 3 D.
Please refer to Fig. 2 and Fig. 3 A.First step 210 that wound is applied the manufacture method 200 of material 100 is formation alginate fiber.It can form at least one alginate fiber 310 by carrying out a wet type spinning process.Specifically, the wet type spinning process is the sodium alginate salt compounds to be dissolved in make the spinning mucus in the aqueous solution, again with the spinning mucus by spin mouth hole extrusion molding in the forming tank that contains divalent metal, form the alginate fiber 310 of solid-state insolubility.In an embodiment of the present invention, alginate can be calcium alginate, alginic acid barium, alginic acid copper, alginic acid zinc, alginic acid silver or alginic acid ferrum.
Alternatively, after forming alginate fiber 310, then can extend alginate fiber 310, to adjust the thread breakage intensity of alginate fiber 310 by drafting process.Drafting process can be carried out by the drawing rollers group.The structure of drawing rollers and the method for drawn fiber are to have in the art knows that usually the knowledgeable knows, and no longer adds to give unnecessary details at this.
Step 220 is for twining alginate fiber 310 on a plate 300.After twining, alginate fiber 310 is understood a section ground and is listed on the surface of plate 300.At this, will be called first fiber 112 at the lip-deep multistage alginate fiber 310 of plate 300.The length of first fiber 112 approximates or is slightly less than the length of plate 300.In an embodiment of the present invention, the length of each first fiber 112 is respectively between 5 centimetres to about 20 centimetres for example about 5,6,7,8,9,10,11,12,13,14,15,16,17,18,19 or 20 centimetres.
Please also refer to Fig. 2 and Fig. 3 B.After twining alginate fiber 310, but execution in step 230, the surface of spraying the alginate fiber 310 of sodium ion aqueous solution 320 after twining.At the surface sprinkling sodium ion aqueous solution 320 of in type alginate fiber 310, can make the surface of alginate fiber 310 omit micro dissolution or softening, and produce mucus.After treating the mucus drying, adjacent alginate fiber 310 just can cohere mutually.
Sodium ion aqueous solution 320 can be the aqueous solution that comprises sodium chloride, and the concentration of the sodium chloride in the aqueous solution can be adjusted according to circumstances.In one embodiment of this invention, the concentration expressed in percentage by weight of the sodium chloride in the sodium ion aqueous solution is between 1% to about 15%, for example about 1,, 3,4,5,, 7,8,9,10,11,12,13,14 or 15%.In an embodiment of the present invention, the concentration expressed in percentage by weight of sodium chloride is about 10%.
Please also refer to Fig. 2, Fig. 3 C and Fig. 3 D.After finishing winding first, earlier with plate 300 rotations, shown in Fig. 3 C.Then, execution in step 240 is twined alginate fiber 310 on plate 300, once more shown in Fig. 3 D.Alginate fiber 310 is understood a section ground and is listed on the surface of plate 300 after twining, and is referred to as second fiber 122 at this.The length of second fiber 112 approximates or is slightly less than the length of plate 300.In an embodiment of the present invention, the length of each second fiber 112 is between 5 centimetres to about 20 centimetres, for example about 5,6,7,8,9,10,11,12,13,14,15,16,17,18,19 or 20 centimetres.
Please refer to Fig. 2, Fig. 3 E and Fig. 3 F.After winding is finished, cut wound along the edge of plate 300 and apply material 100, and wound applied on material 100 slave plates 300 take off, shown in Fig. 3 F.
Then, execution in step 250 is with dry alginate fiber.As previously mentioned, the surface sprinkling sodium ion aqueous solution 320 owing in type alginate fiber 310 can produce mucus.After the mucus drying, adjacent alginate fiber 310 can be cohered mutually.
In an embodiment of the present invention, be to adopt the lyophilization operation to come dry alginate fiber 310.Cryodesiccated method has a variety of, and the also visual actual operation situation of its refrigerated temperature and pressure and adjusting.In an embodiment of the present invention, cryodesiccated temperature is to adopt between pact Celsius-20 to spend between about-55 degree, and pressure is to set to be about 12 handkerchiefs.
Note that in an embodiment of the present invention, though each step is illustrated in regular turn, in fact sequence of steps can change, and the number of times that step is carried out also can be repeatedly.For instance, spraying the step of sodium ion aqueous solution 320 and the step of winding alginate fiber 310 etc. can repeat repeatedly to carry out.
In addition, the step of spraying the sodium ion aqueous solution is not limited to the step (step 220) of twining alginate fiber 310 first and carries out afterwards.The step of in fact spraying the sodium ion aqueous solution can be when twining alginate fiber 310 (step 220) and carrying out first, twine alginate fiber 310 first after, when twining alginate fiber 310 (step 240) and carry out once more or twine once more and wait after the alginate fiber 310 each differently to carry out constantly.
Please refer to Fig. 4, its illustrate according to one embodiment of the invention in order to make as the sketch map of the producing device 400 of the deposited material 100 of wound that Figure 1A illustrated.Producing device 400 has pedestal 410, batches device 420 and tension regulator 430.Batch device 420 in order to batch alginate fiber 310.Batch device 420 and comprise rotating shaft 422 and plate 300, wherein plate 300 is locked in the rotating shaft 422.When rotating shaft 422 is driven and when rotating, during for example along direction 402 rotations, alginate fiber 310 can batch on plate 300.
Because the shape of plate 300 is different from the scroll bar of traditional round tubular, when batching, the change of the length of alginate fiber 310 excessively causes the tension change of alginate fiber 310 during batch, one tension regulator 430 was arranged, to keep the tension force of alginate fiber 310 before batching device 420.
Specifically, a chute 412 is arranged on the pedestal 410, it is other to be positioned at rotating shaft 422.The centre position of rotating shaft 422 alignment chutes 412.Tension regulator 430 is arranged in chute 412, and slides along the bearing of trend of chute 412.
Thus, dwindle to the length variations of the alginate fiber 310 between the edge 302 or 304 of plate 300 between tension regulator 430, to keep the tension stability of alginate fiber 310.
Note that in an embodiment of the present invention the length of chute 412 does not have and limits.For instance, when the edge 302 or 304 of plate 300 forwarded highest point to, it can be higher or lower than an end higher on the chute 412.When the edge 302 or 304 of plate 300 forwarded lowest part to, it can be higher or lower than an end lower on the chute 412.In one embodiment of this invention, when the edge 304 of plate 300 forwards highest point to, the higher end centre of edge 304 and rotating shaft 422 of approximately aliging on the chute 412.When the edge 304 of plate 300 forwards lowest part to, the lower end centre of edge 304 and rotating shaft 422 of approximately aliging on the chute 412.In an embodiment of the present invention, the length of chute 412 can be less than rotating shaft 422 to the twice of the distance at the edge 304 of plate 300 or one times.
Alternatively, tension regulator 430 can couple rotating shaft 422, for example connects rotating shaft 422 by gear, screw rod, belt, cam, trace or other mechanical component.Drive and reciprocatingly slide by rotating shaft 422 along chute 412.
For instance, please refer to Fig. 6 A, it illustrates the schematic rear view of the producing device 400 of one embodiment of the invention.Producing device 400 is provided with cam 431, bar 432 and banded structure 433 as belt.Banded structure 433 connects rotating shaft 422 and cam 431.One end of bar 432 connects tension regulator 430, other end butt cam 431.When rotating shaft 422 is driven and when direction 404 was rotated, it drove cams 431 by banded structure 433 and rotates along direction 406.Because the setting of cam 431 and bar 432, cam 431 meeting catch bars 432 and tension regulator 430 slide along chute 412.
The schematic rear view of the producing device 400 of Fig. 6 another embodiment of the present invention that B illustrates for example again.Rotating shaft 422 is to drive tension regulator 430 by trace 434.Specifically, producing device 400 is provided with trace 434 as crank 435 and rocking bar 436.Banded structure 433 connects rotating shaft 422 and crank 435 as belt.One end of rocking bar 436 connects tension regulator 430, and the other end articulates crank 435.When rotating shaft 422 when direction 404 is rotated, it drives cranks 435 by banded structure 433 and rotates and then drive rocking bar 436 swings along direction 406, makes tension regulator 430 reciprocatingly slide along chute 412.
The schematic rear view of the producing device 400 of Fig. 6 another embodiment of the present invention that C illustrates for example again.Rotating shaft 422 is to drive tension regulator 430 by trace 434.Specifically, producing device 400 is provided with trace 434 as wheel 437 and rocking bar 436.Wherein the two ends of rocking bar 436 articulate wheel 437 respectively near circumference place and tension regulator 430.Banded structure 433 connects rotating shaft 422 and wheel 437 as belt.When rotating shaft 422 when direction 404 is rotated, it rotates along direction 406 by banded structure 433 driven wheels 437, and then drives rocking bar 436 swings, makes tension regulator 430 reciprocatingly slide along chute 412.
In the above-described embodiments, be to utilize banded structure 433 as connecting.Alternatively, banded structure 433 also can change gear train into, is used as the connection between rotating shaft 422 and the tension regulator 430.
By the various embodiments described above as can be known, tension regulator 430 can be by being connected rotating shaft 422 as cam 431, trace 434 and various possible mechanical components, with the same moved further along with the rotation of rotating shaft 422.
Alternatively, also can rotate to detect it, and be adjusted to the position of tension regulator 430 according to testing result by electrically connect rotating shaft 422 as automatic control module.
A variety of in order to plate 300 locking is had at the anchor clamps 424 of rotating shaft 422, for example elasticity folder, C clamp or its combination etc.Please refer to Fig. 7, it illustrates the part enlarged diagram of the producing device 400 of one embodiment of the invention.In an embodiment of the present invention, anchor clamps 424 have a holder 426 and a screw 428.Holder 426 is fixed in the rotating shaft 422, can be placed in wherein for the part of plate 300.Screw 428 is locked in the holder 426, so that plate 300 is locked in holder 426.During the desire dismounting, screw 428 can be unclamped, just plate 300 can be taken off in holder 426.
Be stained with glutinously for fear of alginate fiber 310 and plate 300, the material of plate 300 be the material of not reacting with alginate, and its smooth surface.In an embodiment of the present invention, the material of plate 300 can be acrylic resin (acrylicresin).It is required and change that the shape of plate 300 can be looked closely product, as square, rectangle, rhombus, polygon or circle etc.
Please refer to Fig. 4.In order to make in the coiling process, alginate fiber 310 is distributed on the plate 300 fifty-fifty, and producing device 400 can be provided with reciprocating apparatus 440 before batching device 420, is used for driving alginate fiber 310 and moves back and forth along the direction of principal axis that is parallel to rotating shaft 422.
Specifically, please also refer to Fig. 4, Fig. 8 A and Fig. 8 B, Fig. 8 A and Fig. 8 B are the profile of the hatching line 8 of Fig. 4, and it illustrates the different operating state of reciprocating apparatus 440 respectively.
In one embodiment of this invention, on the bar 442 screw thread is arranged, the screw thread on its mating holes 414.Actuator 444 can be used to dwang 442, and bar 442 is moved back and forth along its bearing of trend.Alternatively, actuator 444 can be linear-motion actuator, and directly catch bar 442 moves back and forth along its bearing of trend.
Note that has a variety ofly in order to drive alginate fiber 310 reciprocating structures, and propose an embodiment at this and only be used as explanation, be not in order to limit the scope of the invention.
In an embodiment of the present invention, producing device 400 can include wet type spinning assembly 450, and it forms alginate fiber 310 in order to carry out a wet type spinning process.The detailed step of wet type spinning process has described in detail as above, does not repeat them here.
In order to strengthen the tension force of alginate fiber 310, producing device 400 can further be provided with drawing rollers assembly 460.Drawing rollers assembly 460 is in order to drawing-off alginate fiber 310, to adjust the thread breakage intensity of alginate fiber 310.
By above-mentioned each embodiment as can be known, the present invention's wound of proposing a kind of alginate apply material 100, its manufacture method with and producing device 400.Shown in Figure 1A, wound is applied material 100 and is had the structure of multi-layer fiber layer, and all fibres in each fibrous layer roughly extends same direction, and different fibrolaminar bearing of trends are not quite similar.Fiber in each fibrous layer is long fine.By the length and the arrangement mode of fiber in each fibrous layer, the fracture strength that makes wound apply material 100 is improved, and then avoids wound to apply material 100 producing fracture during removal or be stained with problem such as glutinous wound from wound.
Though the present invention discloses as above with embodiment; yet it is not in order to limit the present invention; anyly be familiar with this operator; without departing from the spirit and scope of the present invention; when can making various changes that are equal to or replacement, so protection scope of the present invention is when looking accompanying being as the criterion that the application's claim scope defined.
Claims (19)
1. a wound is applied material, comprises at least:
One first fibrous layer is that the material of these first fibers is an alginate by a plurality of first fibrous, and these first fibers cohere mutually, and these first fibers side by side and extend and be roughly parallel to a first direction; And
One second fibrous layer is that the material of these second fibers is an alginate by a plurality of second fibrous, the mutual gluing of these second fibers, these second fibers side by side and extend and be roughly parallel to a second direction, wherein this first direction is not parallel to this second direction
Wherein this second fibrous layer is stacked on this first fibrous layer, and these second fibers cohere these first fibers,
Wherein the length of these first fibers and these second fibers makes this wound apply the fracture strength of material greater than 1.5 kgfs.
2. wound according to claim 1 is applied material, it is characterized in that, this alginate is calcium alginate, alginic acid barium, alginic acid copper, alginic acid zinc, alginic acid silver or alginic acid ferrum.
3. wound according to claim 1 is applied material, it is characterized in that, the fracture strength that the length of these first fibers and these second fibers makes this wound apply material is that 100 kgfs are between 109 kgfs.
4. wound according to claim 1 is applied material, it is characterized in that, the length of each this first fiber is between 5 centimetres to about 20 centimetres, and the length of each this second fiber is between 5 centimetres to about 20 centimetres.
5. wound according to claim 1 is applied material, it is characterized in that this first direction is perpendicular to this second direction.
6. a wound is applied the manufacture method of material, comprises at least:
Carry out a wet type spinning process and form at least one alginate fiber;
Twine this alginate fiber in a plate, to form the surface of a plurality of first fibers at this plate, wherein these first fibers side by side and roughly extend and are parallel to a first direction;
Spray the surface of this alginate fiber of a sodium ion aqueous solution after twining;
Twine this alginate fiber once more on this plate, to form a plurality of second fiber stack on these first fibers, wherein these second fibers side by side and roughly extend and are parallel to a second direction, not parallel this first direction of this second direction; And
Dry these first fibers and these second fibers make these first fibers and these second fibers cohere mutually.
7. wound according to claim 6 is applied the manufacture method of material, it is characterized in that this sodium ion aqueous solution comprises sodium chloride, and the concentration expressed in percentage by weight of the sodium chloride in this sodium ion aqueous solution is between about 1% to about 15%.
8. wound according to claim 6 is applied the manufacture method of material, it is characterized in that this alginate is calcium alginate, alginic acid barium, alginic acid copper, alginic acid zinc, alginic acid silver or alginic acid ferrum.
9. wound according to claim 6 is applied the manufacture method of material, it is characterized in that, also comprises before the step of twining this alginate fiber once more:
Rotate this plate, wherein the anglec of rotation of this plate is the angle of cut between this first direction and this second direction.
10. wound according to claim 6 is applied the manufacture method of material, it is characterized in that, after the step of carrying out this wet type spinning process, also comprises:
By this alginate fiber of at least one drawing rollers drawing-off, to adjust the thread breakage intensity of this alginate fiber.
11. a wound is applied the producing device of material, comprises:
One pedestal;
One chute is positioned on this pedestal;
One tension regulator, this chute that is slidingly connected is to connect at least one fiber; And
One batches device, comprises:
One rotating shaft is rotated in order to drive, and this rotating shaft is alignd and located between the two ends of this chute; And
One plate, locking are in this rotating shaft, in order to batch this fiber that connects this tension regulator.
12. wound according to claim 11 is applied the producing device of material, it is characterized in that, the length of this chute is less than the twice of this rotating shaft to the distance at the edge of this plate.
13. wound according to claim 11 is applied the producing device of material, it is characterized in that this tension regulator couples this rotating shaft, reciprocatingly slides along this chute driven by this rotating shaft.
14. wound according to claim 11 is applied the producing device of material, it is characterized in that, also comprises:
At least one cam connects this tension regulator.
15. wound according to claim 11 is applied the producing device of material, it is characterized in that, also comprises:
At least one banded structure connects this rotating shaft.
16. wound according to claim 11 is applied the producing device of material, it is characterized in that, also comprises:
One reciprocating apparatus, this pedestal that is slidingly connected is in order to connect this fiber and to reciprocatingly slide along an axial path that is parallel to this rotating shaft.
17. wound according to claim 16 is applied the producing device of material, it is characterized in that this reciprocating apparatus comprises:
This pedestal is run through in one hole;
One screw rod passes this hole; And
One actuator in order to promote this screw rod, makes an end of this screw rod change to the spacing between this hole.
18. wound according to claim 17 is applied the producing device of material, it is characterized in that this reciprocating apparatus also comprises:
One through wires hole is positioned on this screw rod, passes for this fiber.
19. wound according to claim 11 is applied the producing device of material, it is characterized in that this batches device and comprises:
One anchor clamps connect this rotating shaft, in order to lock or to unclamp this plate.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200910265956 CN102100592B (en) | 2009-12-21 | 2009-12-21 | Alginate wound dress material and manufacturing method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200910265956 CN102100592B (en) | 2009-12-21 | 2009-12-21 | Alginate wound dress material and manufacturing method thereof |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310119490.2A Division CN103211681B (en) | 2009-12-21 | 2009-12-21 | Alginate wound dressing as well as manufacture method and manufacture device of alginate wound dressing |
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| CN102100592A true CN102100592A (en) | 2011-06-22 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999020378A1 (en) * | 1997-10-20 | 1999-04-29 | Korea Research Institute Of Chemical Technology | A manufacturing method of composite membrane having hydrophilic coating layer on hydrophobic support membrane |
| WO2005087287A1 (en) * | 2004-03-05 | 2005-09-22 | University Of Florida Research Foundation Inc. | Novel tissue engineered scaffolds derived from copper capillary alginate gels |
| US20090138082A1 (en) * | 2007-11-19 | 2009-05-28 | Nuvasive, Inc. | Textile-Based Plate Implant and Related Methods |
-
2009
- 2009-12-21 CN CN 200910265956 patent/CN102100592B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999020378A1 (en) * | 1997-10-20 | 1999-04-29 | Korea Research Institute Of Chemical Technology | A manufacturing method of composite membrane having hydrophilic coating layer on hydrophobic support membrane |
| WO2005087287A1 (en) * | 2004-03-05 | 2005-09-22 | University Of Florida Research Foundation Inc. | Novel tissue engineered scaffolds derived from copper capillary alginate gels |
| US20090138082A1 (en) * | 2007-11-19 | 2009-05-28 | Nuvasive, Inc. | Textile-Based Plate Implant and Related Methods |
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| CN102100592B (en) | 2013-05-22 |
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