CN102028478A - Blood sample collecting device and kit - Google Patents
Blood sample collecting device and kit Download PDFInfo
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- CN102028478A CN102028478A CN2009101789199A CN200910178919A CN102028478A CN 102028478 A CN102028478 A CN 102028478A CN 2009101789199 A CN2009101789199 A CN 2009101789199A CN 200910178919 A CN200910178919 A CN 200910178919A CN 102028478 A CN102028478 A CN 102028478A
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Abstract
The invention relates to a blood sample collecting device and a kit, which can be easily used by people who do not receive medical training or learn other expertise or knowledge to alleviate pains. Two parts on a first side are provided with flexible stripes with adhesive, and an absorbent pad and a substrate with a microstructure are arranged between the two parts. The substrate comprises a microstructure which is an external surface capable of mildly penetrating or puncturing skin to make blood flow into the body of a user. The absorbent pad can receive or absorb a blood sample and support various chemical agents which can further improve the blood mobility in a collecting system. The chemical agents include anticoagulant or blood anticoagulant, thereby being beneficial to blood transfer from donors to the absorbent pad. In addition, blood preservative is available in the system for stabilizing collected blood in long-distance transportation and transfer. The blood sample collecting systems can be further provided with anesthetics for improving comfort level of use.
Description
Technical field
The disclosure of invention relates generally to blood sample harvester and test kit, relates to the inartful user of service particularly and can use device and test kit with complete operation in family's environment for use.
Background technology
The modern medicine analytical system is full-fledged to certain phase, need not to go to inexpediently ground such as Doctor's office, laboratory, infirmary can cheaply also easily carry out meticulous test thus.Especially, the blood metabolic analysis that carries out at the modern laboratory of advanced person only needs patient to provide very small amount of blood as sample.Remain the process of in the controllable environment with professional expensive device such as Doctor's office or hospital, carrying out to a great extent although take a blood sample by the medical professional who accepted medical step advanced training (for example nurse) for metabolic analysis, new health idea suggestion is omitted and is gone for doctor/hospital and use the method for " directly satisfying the needs of consumers " to replace, this method comprises by wieldy submits for example blood of biological substance sample to from complete sample collection system, and described system can directly fully be used by consumer.
At present, when people need analyze the blood metabolite, draw blood with professional equipment (for example aseptic collection and pricking device) by the professional.The nurse understands following collection blood: be needled into skin with subcutaneous injection, blood be extracted in the suitable vessel, remove pin, the dressing piercing orientation, and by the inner medical material processing system in clinic with this sample transport to suitable testing equipment.
Although most of blood drawing is undertaken by the professional, but still exists people to carry out the common procedure of self-fulfillment blood draw.Accepted in shortage under professional's the help of medical step training, people can puncture the skin of oneself, collect blood sample and the blood of gathering is transported to testing equipment.Certainly, most of glycosuria patients that every day, routine was carried out similar operations know this process.In most of ASs, diabetics uses miniature lancet device (bearing spring sometimes) to thrust skin, and can collect droplet blood (for example being collected on the test strip with reactant) this moment from tissue surface.Subsequently, blood is tested to determine the glucose level in the blood.
Though be not strictly relevant, have the key property relevant with the instruction that provides at this as the cheap common binder that bonds band with the blood sample acquisition system.Usually use Band-
The disposable band binder of type stops bleeds and protects new wound to avoid bacteria attack.This binder comprises the plastic strip that combines absorption pad or adhered to absorption pad thereon usually.In addition, plastic strip all comprises binding agent on any side of pad, and this binding agent allows this equipment to attach and remains on the unmarred skin of wound circumference.When appropriate application, described binder is removed from wound with absorbing blood and fluid and with them.Over time, wound healing and can remove and abandon binder.In some high functional forms, thereby can also additionally comprise the bacterial growth that chemical addition agent stops careless omission.Can add antibacterial in absorption pad, wound is further protected thus exempts from infection.Only use binder and also can use antibacterial.Although suchlike binder is from tissue aspiration blood, in fact they are not suitable for the function of sample of blood, drawn.
Although prior art system and invention are designed to realize concrete target and purpose, some of them also are significant really, yet these inventions of prior art still comprise some restrictions, and these restrictions stop these inventions to be used in current possible new mode.The invention of prior art is not used to and can not be used to realize the advantage and the target of the instruction that provides below this paper.
Summary of the invention
The blood sample harvester of James's Prandtl, David Bake, Michael's Nova and Lu Kenuosaike and test kit invention comprise device and the test kit with skin penetrating structure, and described skin penetrating structure is applied on the skin surface by the binding agent on the thin band.
The blood sample acquisition system is designed to plastic strip, and this plastic strip combines skin piercing element and absorption pad.When on the surface of organizing arm for example that is applied to the donor, piercing element destroys the integrity of skin and impels blood to be drawn onto on the surface.The blood that leaves tissue contacts with absorption pad and is further sucked and be contained in the absorption pad.
In most of most important forms, piercing element forms the micro structure system of tiny pin or lancet or hook.These operations that obtain can not have prick skin under the excessive pain.Be similar to the mode of mosquito prick skin, thereby artificial microneedle can be inserted the enough dark blood vessel that reaches of tissue, is very easy to simultaneously be discovered when the people is injected.
In the form of using microneedle, pin can be used for providing the conduit that flows to absorption pad from blood vessel for blood.In the concrete form that forms hook class micro structure,, hook guarantees that this device is enough to extract blood thereby advancing piercing element to enter tissue.In fact, the action of generation is easy to force hook to enter and organizes more depths.In some forms, only depend on land punch die (lands die) micro-knife just to be enough to prick skin and to impel blood to be discharged on the absorption pad.
In some form, thereby also additionally combine the chemical agent enhancing on the absorption pad or bring relevant critical function.In first form, use anticoagulant or anti-agglomeration hemodilution chemicals to guarantee that blood can more easily flow to absorption pad from blood vessel.In selectable other forms, interpolation anesthetis or pain are slowed down medicine and are alleviated the sense of discomfort that is produced by piercing element.In other important form, test kit can be provided, special device is set therein is used for comprising and preserving blood sample at packing material, described packing material is configured to use with both privately and publicly owned's transportation service.
In most of preferred forms, provide indicator to receive the state of capacity blood with caution user absorption pad.In the shop, on the visual surface of donations user, provide reactant.
Goal of the invention
Main purpose of the present invention provides new blood sample acquisition system.
An object of the present invention is to provide by not being subjected to the exercisable blood sample acquisition system of professional medical science training or empirical consumer.
Another object of the present invention provides and posts the blood sample acquisition system with private transportation service compatibility.
An object of the present invention is to provide the preservation blood sample and reach 1 to 14 day blood sample acquisition system.
Thereby an object of the present invention is to provide the blood collecting system of taking the q.s blood sample to support metabolism blood testing system.
Can understand the present invention better with reference to detailed description of preferred embodiments and accompanying drawing.Given embodiment is realization concrete mode of the present invention but does not comprise that institute might a mode.Therefore, exist and not deviate from the open scope and spirit of claims but in this embodiment that does not occur as specific embodiment.Be to be appreciated that a great selection of embodiment of selecting is possible.
Brief Description Of Drawings
With reference to following explanation, claims and accompanying drawing, can understand each feature of the present invention, aspect and advantage better, wherein:
Fig. 1 is the view of two opposite sides of the bonding band of these systems;
Fig. 2 is the sectional view of the blood sample acquisition system of present disclosure;
Fig. 3 is a critical elements---the close-up illustration of the spatial distribution of absorption pad and cooperation chemicals;
Fig. 4 is the three-dimensional view of the example integrated mutually of absorption pad and the piercing element of preferred blood sample blood sampling system;
Fig. 5 shows the sectional view of another concrete support component;
Fig. 6 has the single micro structure of concrete property and the utmost point close-up illustration of cooperation substrate;
Fig. 7 has shown the optional form of the micro structure with particular importance;
Fig. 8 shown test kit of the present invention with and the solid that is in the element of cooperation relation attempt.
Preferred embodiment
Each preferred embodiment according to the present invention provides blood sample harvester and test kit.Should recognize that described each embodiment comprises device and/or test kit, and the device of a preferred embodiment and/or test kit are different from the device or the test kit of another embodiment.Therefore, the part of any alternative should not married again and be assumed to be vaguely to the restriction among embodiment.
With reference to the accompanying drawings, Fig. 1 especially, Fig. 1 shows the front view and the rearview of first kind of form of blood sample harvester of the present invention with simple string diagram.Main body strip member 1 provides support and structure, thereon in conjunction with and/or integrated other collaboration elements.Especially, bonding material 2 is distributed on the large tracts of land part of strip face of each side of center.Preferred binding agent comprises and the compatible binding agent of human skin use, and more specifically, comprise further the binding agent that comprises " release " ability, thus do not have remarkable pain and uncomfortable or band is discharged before the tissue of institute junction cause the combination that can separate under the situation of damage between skin and the band.
The substrate 3 of rigidity or semi-rigid material forms substrate, thereby micro-structured component 4 formation are thereon stretched out from the base plane quadrature.In some most important forms, substrate can be specially crystalline silicon wafer.In some forms, by crystal growth, etching and microlithography technology (microlithhography) can provide micro structure.In these forms, the substrate element of these micro structures of growing thereon is silicon preferably, because semi-conductor industry is developing many important performances aspect the si wafer processes science.Yet because silicon wafer does not almost have function value after providing crystal seed and mechanical support for micro structure, many alternatives are possible.Therefore, the major function that should be noted that substrate described here is can provide identical functions for micro structure provides mechanical support and many alternative materials.
In the optimal form of these devices, a plurality of providing within it and hole 5 that spatial distribution is opened is provided base members.These holes provide the path from first side of substrate to the blood-transmitted of opposite side.By hole wherein, the blood that substrate first side occurs can easily flow to opposite side.Similarly, by natural migration, other chemical substances on substrate one side can easily flow to opposite side.Therefore, no matter what the composition material of substrate is, prepares these substrates and therefrom easily flows through to allow fluid.
What combine with substrate is the absorption pad 6 that cloth or fiber non-woven substrate form with for example sheet form.Provide pad to be used for reception, absorption and storage of blood sample.
In an important optional form, absorption pad is made by the element of sponge or similar sponge.The sponge that synthetic material is made is attractive especially because it provides some extra function values.In an example, " elastomer " sponge makes blood sample keep the time of prolongation effectively under drying condition.Described sample can be by rehydrated and remove to test from sponge.After the absorption pad of being made by the elastomer sponge receives this sample, can or even use desiccant to quicken drying with this sample natural drying.Key character at the absorption pad of this instruction needs them to have adsorptivity, is fit to the longer-term storage biological substance, is fit to and band polymer or plastic strip is integrated and bonding for example.
Other features and function at this pad element that provides are to be used for storing and carrying various chemical agents, provide described various chemical agent to help the function and the target of these systems.
By permanent glue bond agent absorption pad is adhered to and is attached on the band, unless produce destructive consequence thus otherwise it can not be separated from band.This pad preferably is positioned at the central area of band as shown in the figure.Although its shape is not crucial, the purpose of native system suggestion length-width ratio approximates 1 ellipse or rectangle greatly.When blood discharged on small size, it tended to nature and spreads on two dimension equably, and therefore when absorption pad when symmetrical, this pad provides better function.
Second side of main body band provides extra critical function.Because the main target user at the device of this instruction is not the expert of medical step, it is very important therefore providing clearly instruction and mechanism.This is comprising indicator system, and it is provided with provides the optical signal indication that absorbs the user mode and the condition of enough blood volumes about absorption pad.
In first form, opaque cap member 7 has the perspective window mouth 8 with definite shape that is combined in wherein.Be reactant or change medium 9 that at this window and cap member back when for example blood reacted with certain regulation material that exists, described reactant or variation medium can produce change color or other change of state.At reactant or change in the important example form of medium, the variation of material response pH value and change color.When the chemicals (for example blood) of pH value of regulation when existing, reagent to second color, perhaps changes to opaque from first change color from clarification.Non-science or unskilled user are easy to discern the optical signal of this variation.
Comprise a kind of system based on the variation medium in another important form of the indicator system that uses with these devices, this variation medium changes its polarization state when blood exists.In this form, thereby window is configured to especially cooperate with the polarization state of this variation medium and forms the indicator system of this form.The polarizer that window can be set to a kind of character changes the polarizer of medium (when blood exists) as cooperation character simultaneously.They can produce useful optical signal at window jointly.
In the optimal form of these indicator systems, window shape has the periphery through special consideration.In order to indicate " affirming " or " positive " state, for example can use symbols such as " √ " or "+" labelling, because it is easy to read and provide at once determining required state beyond all doubtly.This makes the signal that the easier explanation of non-expert personnel is provided.
Can realize these blood sample harvesters are better understood in conjunction with the side view of Fig. 2 and the detailed description of this paper, another important exemplary forms is provided among Fig. 2.For the sake of clarity, the mapping ratio on orthogonal dimensions is different.Ratio on horizontal dimensions with greater than 3 or bigger coefficient be exaggerated.Should be appreciated that these devices are a plurality of extremely thin bands by specific design.The chart of many thin bands can be beyonded one's depth.Therefore in fully clearly further view, the element as thin as a wafer among the figure that Fig. 2 provides is drawn by magnification ratio.
Band main body 21 parts two ends thereon all have binding material 22.The binding agent that uses in the binder of common strip-type equally works in these devices.The binding material that is applied on band one side forms interim the combination with human skin.Although described combination is durable, after the short time, can only can discharge by the band of tearing from the adherent site of band.
Integrated substrate 24 on the absorption pad, thereby in this substrate, formed and mechanical support micro structure 25 formation piercing elements.The piercing element of these devices can have a plurality of single micro structures, and each micro structure can independent operation and prick skin, yet for this nomenclature, the set of whole substrate and all micro structures is called as " piercing element ".Such piercing element can with crystal growth technique form and can with made separately before absorption pad combines.
In an optional form, at first directly adhere to substrate on the band and place absorption pad thereon.Micro structure can be passed absorbent pad material and be exposed on opposite side.These forms make to make to be simplified.The exact position of piercing element substrate is not crucial---but thereby the piercing element substrate location preferably allows to use shorter stronger micro structure near the apparatus for assembling surface.
On the opposite side of band, indicator system comprises variation medium 26, cladding element 27 and window 28.Described band can further be equipped with through hole 29, and it allows a certain amount of blood to flow to the variation medium from absorption pad.Flow out from absorption pad and to enter the blood that changes medium or " reactant " through through hole and cause wherein change of state.This change of state can provide optical signal, and user can be observed this optical signal by window.
The absorption pad of these systems comprises following major function: receive, store and preserve the time that blood sample reaches prolongation, thereby and further carry and send in some cases chemical agent and improve systemic-function.As for the chemicals that improves function in this type of absorption pad that is included in some forms, they can comprise: antiseptic, anticoagulant, anesthetis etc.
Sometimes use anesthetis to improve the comfort level of user.Because these devices must puncture user skin, slight less pain is followed in normal use sometimes.Although having formed some is that the skin of target punctures micro structure to reduce pain, their use bring slight pain still can for sometimes some more responsive user.Therefore, anesthetis can be included as the part of system.In the place of apparatus for placing and user contact skin, anesthetis is passed to the tissue of user, can be absorbed and in order to reduce any pain that causes because of further puncturing of micro structure at this tissue place anesthetis.
Can comprise anti-agglomerating agent or anticoagulant with the second functionalized chemical agent that absorption pad combines.In order to improve the flowability of the blood that receives in the absorption pad, in this type of blood sample harvester of some forms, can use anticoagulant or blood thinners.It is useful making absorption pad have that stronger adsorptivity comparatively fast siphons away blood and blood is immersed deeply absorb bed course from skin surface thus.For this purpose, when blood arrives and the blended anticoagulant of blood make blood easily enter absorption pad and move therein.Further, in the form of configuration indicator system,, blood passes through the entire depth of all layers with final arrival reactant thereby must having sufficiently high flowability.Be this reason, the anticoagulant that combines with absorption pad has further improved system functionality.
These system's purposes are to be provided at very unique remarkable function of not finding in other blood sample acquisition systems.Particularly, because the main purpose of these devices is to non-expert or do not have the personnel of special medicine technology to use in the family, thereby be necessary to provide machinery and functional character support not to be subjected to the personnel's that train use.In addition, also support to transport or the use of Transportation Model.Just, after device receives blood, this device must be in the time that prolongs storage of blood sample and keep blood sample in shape, blood sample can for example be transported to testing equipment from the consumption user between about one day to five days thus.Therefore, the form of these systems comprises that special support packing (following will the detailed description in detail) and chemical agent are to preserve and the stabilised blood fluid samples in the time that prolongs.Described chemical agent can comprise antibacterial, blood stable chemical etc.
Because with each the relevant function in these chemical agents is different, it is favourable providing these chemical agents in the spatial distribution mode of improving their functions sometimes.Promptly preferably near exposed surface or its, provide anesthetis, because anesthetis only plays a role when user is organized entering by the adherent site of device.Thus, these devices are preferably in the anesthetis that high concentration is set near absorption pad exposed surface place.In addition, although blood fluidity integral body is all very important, may tend to agglomerative surface and internal structure place at blood, blood fluidity is more important.In case blood distributes good and when all directions arrived the reactant of indicator system, flowability just receded into the background.Therefore, in some forms, concentration is as the function of radius " r " and the radial distribution that reduces has been improved the performance of this respect.
In another important space is considered, wish that blood is distributed in the whole device to be saved.The bacterial growth that stops any one is important.Thus, in the peak performance form, wish the antiseptic uniform distribution.Therefore, the chemical agent that comprises in these devices can comprise the concrete function favourable spatial distribution relevant with its function with chemicals.
Fig. 3 A and 3B show an exemplary forms of the spatial distribution of the chemical agent that uses in the absorption pad of these forms.Absorption pad 31 combines substrate 32, micro structure 33 by mechanical support in this substrate 32.Thereby in absorption pad, can provide the fluid blood thinners to be convenient to increase blood fluidity as shown.By this way, the blood of absorption pad surface reception can be impelled towards the absorption pad apparent surface mobile.Absorption pad exposed surface 35 places and near, can step chemical anesthetis 36.By this way, in case absorption pad contacts with the user skin surface, anesthetis is easy to be transferred to skin surface.In second view 3B of same absorption pad, chemicals 37 distributes equably.All parts at absorption pad that can absorbing blood provide antibacterial or other blood antiseptic.
An importance of these blood sample acquisition systems relates to the mode that micro structure is kept installing perpendicular to these first type surfaces.Fig. 4 is the axonometric chart of a multilamellar that works or multi-disc.Substrate 41 for example silicon wafer provides rigid foundation, can form a plurality of micro structures 42 thereon.Substrate may further include equally distributed macropore 43.The convenient transportation of fluid in the substrate both sides realized in these holes.Cloth, fabric or nonwoven sheet 44 form the first of absorption pad together.Extra play 45 on the substrate opposite side has also formed the part of absorption pad.When all layers that comprise silicon wafer were brought together the formation absorption pad, substrate was embedded between them.Though substrate no longer exposes also no longer visual, the micro structure tip is passed the layer of a side and is kept exposing.Therefore, absorption pad is considered to combine the support structure (substrate) that is used for micro structure.
Fig. 5 is the side view of a form of these blood collecting systems, and this form has illustrated especially special protection cap member.For example the main body band made of plastics 51 forms the basis, directly adheres to substrate 52 thereon.Absorption pad 53 is placed in the substrate in one way, and their top exposure can be extended and make to micro structure 54 by absorption pad thus.In this form, substrate is directly adhered on the plastic strip rather than is combined on the absorption pad.
All has binding material 55 on the main body band end in office.By this way, device can be applied to skin surface so that micro structure and absorption pad and contact skin also are attached on the skin well.Though the major function of binding material is to be attached on the user skin, secondary function also comprises adheres on the device over cap temporarily.
Over cap 56 can be duroplasts or half-duroplasts cap member, and this cap member is protected this device before operative installations.Over cap can comprise the spatial content that is used for micro structure, and this over cap provides those micro structures occupied remarkable volumetric spaces thus.At this point, some forms of these over caps include the female cap element.Be different from flat sheet, these over cap elements can comprise " hollow of the knee " part 57 and second straight portion 58.When over cap being remained on the main body band by binding agent, the hollow of the knee part and second straight portion provide the chamber, space at micro structure place.
In some preferred forms, over cap partly is made of two collaboration elements.Shown in these can form overlapping 59.When removing over cap before being applied to user/donor's skin surface, this over cap can easily discharge from binding agent.In case over cap is removed and abandons, micro structure is exposed and can be applied on the user skin surface.
In some concrete forms, advanced micro structure forms certain profile to improve the functional of whole system.To be similar to the mode that mosquito is attacked its host with blood thinners, these systems can be provided with the chemical substance of the specific purposes of being convenient to the blood absorption.Figure 6 illustrates specialized substrate 61, it has the micro structure 62 of hypodermic needle type.Hole 63 provides mode, and the chemical blood thinners 64 that is stored in substrate chamber or the memorizer 65 can be transferred to the donor from device by this mode.Need not mechanism and come the injected chemical product, the natural fluid of blood moves and is easy to impel chemical agent to mix with blood and dilute blood at the place, hole.Blood and diluent can be further mix and finally impel blood more easily to be extracted into absorption pad and flow to absorption pad in injection site.
The micro structure of another important kind relates to a kind of micro structure that further helps device to pierce through its applied user tissue, and also natural imitation circle.Can form " hook " type micro structure by crystal growth, microlithography art and etch process on suitable substrates, hook passes through tissue with preferred orientations thus.Because these devices only are applied to skin surface, do not cause the typical machine means of injection, the light pressure that they produce when depending on slight the contact.Thereby enter the trend that tissue enough reaches blood deeply in order to improve micro structure, the hook-type micro structure is kind of an improvement in some forms.Fig. 7 has shown this form.Silicon base 71 has been grown thereon and has been had lenticular hook 72 elements of tip 73 and hook 74.Although diagram only shows single hook micro structure, thereby should be appreciated that and to provide many even up to a hundred hooks make system can puncture tissue and therefrom extract blood sample at substrate surface that described blood sample is absorbed into the absorption pad of cooperation.
Although core parts most critical described herein ground comprises device or the equipment that is used to gather blood on donor's skin that adheres to, the important optional aspect of the present invention comprises this device and supports test kit.In some preferred embodiments, the blood collection test kit that use easily, directly satisfies the needs of consumers comprises the blood collection device as main element.In addition, these test kits comprise transport case 81, this transport case is fit to for example to serve Federal Express or UPS is using the round transport between donor and the laboratory to send by government's mail service or private postal delivery, comprises that supporting user to carry out label (address) changes.
In addition, these blood collection test kits that directly satisfy the needs of consumers comprise and are used for setting that the article that transport at different vessels are supported.Has the reception cavity that comprises two uniquenesses with transport case core foam element 82 of symmetric outer surface on size and dimension in addition; comprise: be used for receiving therein and keeping the groove reception cavity 83 of untapped fresh blood harvester 84, described blood collection device is comprised in the disposable big envelope 85 of protective sterilized.In addition, the core foam element comprises and is used for holding the reception cavity 86 that plastics return container 87 that described plastics return container can comprise blood stabilizing solution and impregnating fluid therein.In addition, described container also provides fluid-tight seal, and described fluid-tight seal is fit to the safety of medical science and biological substance and holds.Further, described test kit can further comprise instruction card or pamphlet 88, and it comprises text and/or chart so that correct usage to be described.At last, test kit can also comprise the label 89 of wieldy fill address in advance, and the address of the two-way transport case of the feasible round transport of described label can be changed.The major function of these test kits be make any acceptance cross few training or do not accept the training the people can easily blood sample be put into safety container to turn back to laboratory.
People can understand directly satisfy the needs of consumers demand, advanced, easy-to-use blood sample harvester and test kit of support fully and how to realize.Although with the clear and accurate language by a large amount of details and comprise the best mode that the inventor expects with reference to preferred forms more of the present invention invention has been described that other form is possible.Therefore, the restriction that the spirit and scope of the present invention should not be subjected to comprising herein to the description of preferred form, but be subjected to the restriction of claims.
Claims (23)
1. blood sample harvester comprises:
Piercing element;
Absorption pad; And
The bonding band,
Described piercing element is adhered on the described absorption pad, and described piercing element has at least one puncture micro structure that basic quadrature extends on it,
Described absorption pad is adhered on the side of described bonding band, and described band all has binder material on the either side of described absorption pad.
2. blood sample harvester according to claim 1, described absorption pad comprise a plurality of layers and described piercing element is incorporated in the layer of described absorption pad.
3. blood sample harvester according to claim 1, described piercing element comprises the planar structure that is formed by wafer.
4. blood sample harvester according to claim 3, described micro structure forms by crystal growth technique.
5. blood sample harvester according to claim 3, described micro structure are the wafers that has a plurality of holes therein.
6. blood sample harvester according to claim 3, described at least one puncture micro structure is selected from lancet, hook, pin, pin, cutter, spike.
7. blood sample harvester according to claim 6, described at least one piercing element is hypodermic needle.
8. blood sample harvester according to claim 7, described pin forms with the substrate that has memorizer therein is whole, and described memorizer comprises blood thinners or anticoagulant.
9. blood sample harvester according to claim 6, described at least one piercing element is a hook.
10. blood sample harvester according to claim 1, described absorption pad further comprise at least a chemical agent that is incorporated into wherein.
11. blood sample harvester according to claim 10, described at least a chemical agent is selected from: anesthetis, anticoagulant, the agent of blood anticoagulant knot, blood thinners, antibacterial, antiseptic and blood stabilizing agent.
12. blood sample harvester according to claim 11, described at least a chemical agent comprises the number of chemical agent, and wherein arbitrary chemical agent spatially separates with arbitrary another kind of chemical agent.
13. blood sample harvester according to claim 12 further is included in the anesthetis that the exposed surface of described absorption pad is placed the most nearby.
14. blood sample harvester according to claim 1, further comprise the indicator system that is oppositely arranged with described piercing element, described indicator system produces response to the capacity blood that exists in described absorption pad, described indicator system is configured to provide visual sign when having blood.
15. blood sample harvester according to claim 14, the chemical state that described indicator system produces based on response is made in the existence of the material of regulation pH changes.
16. blood sample harvester according to claim 15, described indicator system comprise the tangible labelling of " positive " or " affirming " character of "+" symbol for example or " √ " symbol.
17. blood sample harvester according to claim 14, described indicator system comprises the cap member that wherein has window, and the medium that changes state when blood exists.
18. blood sample harvester according to claim 17, described cap member with change medium and be set on the described bonding band and the relative side of a side that adheres to described absorption pad, described bonding band has through hole therein, and the blood in described absorption pad can move in the described variation medium thus.
19. blood sample harvester according to claim 1 further comprises removable over cap element, described over cap element is configured to by the interim micro structure that adheres to and further cover and protect described device of described band binding agent.
20. blood sample harvester according to claim 19, described cover fillet band further comprise " hollow of the knee " thereby discontinuity is created cavity between described lid and described binding agent, can hold described micro structure in described cavity.
21. blood sample is gathered test kit, comprising:
Durable external container;
Core foam;
The blood sample harvester;
Sterile enclosure; And
Return container,
Described durable external container is fit to the mode transmitted in both directions with mail or private transportation service, and has the outer surface that is fit to hold the address information that can change,
Described core foam is similar substantially but slightly little on shape and size, and described thus core foam is engaged in the external container suitably, and described core foam further has at least two holes that form or groove within it to hold described big envelope and to return container.
22. blood sample according to claim 21 is gathered test kit, described blood sample harvester is the blood sample harvester that comprises following parts: piercing element; Absorption pad; And bonding band, described piercing element is adhered on the described absorption pad, described piercing element has the puncture micro structure that at least one basic from it quadrature extends, described absorption pad adheres on the side of described bonding band, and described bonding band all has binder material on described absorption pad either side.
23. blood sample according to claim 21 is gathered test kit, further comprises preprinted return address label and system's operation instruction regulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101789199A CN102028478A (en) | 2009-09-29 | 2009-09-29 | Blood sample collecting device and kit |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101789199A CN102028478A (en) | 2009-09-29 | 2009-09-29 | Blood sample collecting device and kit |
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| CN102028478A true CN102028478A (en) | 2011-04-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2009101789199A Pending CN102028478A (en) | 2009-09-29 | 2009-09-29 | Blood sample collecting device and kit |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103027693A (en) * | 2011-10-05 | 2013-04-10 | 生物梅里埃公司 | Assembly for determining the presence or absence of an analyte in a blood sample and analysis unit comprising such an assembly |
-
2009
- 2009-09-29 CN CN2009101789199A patent/CN102028478A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103027693A (en) * | 2011-10-05 | 2013-04-10 | 生物梅里埃公司 | Assembly for determining the presence or absence of an analyte in a blood sample and analysis unit comprising such an assembly |
| US9480428B2 (en) | 2011-10-05 | 2016-11-01 | Biomerieux | Assembly for determining the presence or absence of an analyte in a blood sample and analysis unit comprising such an assembly |
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Application publication date: 20110427 |