CN102020595A - Ethylene glycol bis-sulpho succinic acid bis(4-methyl-2-amyl) ester sodium and production method thereof - Google Patents
Ethylene glycol bis-sulpho succinic acid bis(4-methyl-2-amyl) ester sodium and production method thereof Download PDFInfo
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- CN102020595A CN102020595A CN2010105240554A CN201010524055A CN102020595A CN 102020595 A CN102020595 A CN 102020595A CN 2010105240554 A CN2010105240554 A CN 2010105240554A CN 201010524055 A CN201010524055 A CN 201010524055A CN 102020595 A CN102020595 A CN 102020595A
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Abstract
The invention discloses a production method of ethylene glycol bis-sulpho succinic acid bis(4-methyl-2-amyl) ester sodium, which comprises the following steps of: reacting maleic anhydride with 4-methyl-2-amyl alcohol to generate a single esterification product, reacting the single esterification product with sodium sulfite to generate a sulfonation product, and reacting the sulfonation product with ethylene glycol to generate the ethylene glycol bis-sulpho succinic acid bis(4-methyl-2-amyl) ester sodium. The product has high property and is simply synthesized.
Description
Technical field:
The present invention relates to a kind of ethylene glycol bis sulfo-succinic acid two (4-methyl 2-amyl group) ester sodium and production method.
Background technology:
There is shortcoming in existing tensio-active agent at aspects such as serviceability, use range, produce also complicated.
Summary of the invention:
The object of the present invention is to provide a kind of performance good, synthetic simple ethylene glycol bis sulfo-succinic acid two (4-methyl 2-amyl group) ester sodium and production method.
Technical solution of the present invention is:
A kind of ethylene glycol bis sulfo-succinic acid two (4-methyl 2-amyl group) ester sodium, it is characterized in that: its chemical structural formula is:
The production method of a kind of ethylene glycol bis sulfo-succinic acid two (4-methyl 2-amyl group) ester sodium is characterized in that: comprise the following steps:
(1) single-esterification: with cis-butenedioic anhydride and 4-methyl-2-amylalcohol reaction, form the mono-esterification product, reaction formula is:
(2) sulfonation reaction: mono-esterification product and sodium bisulfite reaction with step (1) obtains, form sulfonated products, its reaction formula is:
(3) sulfonated products and the glycol reaction that obtain of step (2) just obtains ethylene glycol bis sulfo-succinic acid two (4-methyl 2-amyl group) ester sodium, and reaction formula is:
During single-esterification, be catalyzer with the alkylsulphonic acid catalyzer.
Sulfonation reaction is to carry out under the atmosphere protection of nitrogen.
When sulfonation reaction finishes, also carry out branch water with toluene.
Add the carbonyl solid acid catalyst during double esterification reaction.
During double esterification reaction, added toluene is as the band aqua when finishing with sulfonation reaction.
Ultimate principle of the present invention: the cis-butenedioic anhydride open loop, the hydroxyl of its carboxyl and 4-methyl-2-amylalcohol is combined, R forwards another carboxyl to and gets on, and forms monoesters; Monoesters product that generates and sodium bisulfite electrophilic addition reaction generate sulfonated products; Sulfonated products is carried out double esterification reaction with ethylene glycol again and is generated the purpose product.
Ethylene glycol bis sulfo-succinic acid two (4-methyl 2-amyl group) ester sodium is that design connects the Gemini surface active agent that forms with the ion head of single linked list surface-active agent sulfo-succinic acid (4-methyl 2-amyl group) ester sodium salt as two parents' molecules through linking group ethylene glycol by chemical bond in molecule.Its tensio-active agent also has the promptly higher surfactivity of lower surface tension, lower micelle-forming concentration, very low Kraff point, peculiar viscosity characteristics, good synergistic etc. except all advantages of conventional surfactant with single alkane chain and single ion head.Because its special structural table reveals its particular performances, thereby widespread use more.As except in the conventional field as high duty detergent, emulsifying agent, efficient solubilizing agents, emulsion and suds-stabilizing agent tackifier etc., thereby also in nano material preparation, reach aspect such as repairing environment as molecular device nonaqueous phase liquid and absorption soil pollutant in medicine is synthetic, in the bioseparation such as enzyme, in the solubilising of dispersed dye, tertiary oil recovery, expeling underground water and have a wide range of applications.
Product of the present invention is a kind of new compound, its tensio-active agent also has higher surfactivity except all advantages with the preferable wetting and penetrating quality of performances such as the good dissolving of single linked list surface-active agent, solubilising, dispersion and emulsification and succsinic acid symmetric double sulfonated ester.Except in the conventional field as high duty detergent, emulsifying agent, efficient solubilizing agents, emulsion and suds-stabilizing agent tackifier etc., thereby also in nano material preparation, reach aspect such as repairing environment as molecular device nonaqueous phase liquid and absorption soil pollutant in medicine is synthetic, in the bioseparation such as enzyme, in the solubilising of dispersed dye, tertiary oil recovery, expeling underground water and have a wide range of applications.
The inventive method adds a small amount of solvent when sulfonation reaction finishes, the moisture in the sulfonated products is removed in the backflow of employing solvent azeotropic.Sulfonated products is as the raw material of double esterification reaction, at first need remove moisture wherein, present method adopts the solvent azeotropic to reflux, and solvent is directly added in same the reactor, and the sulfonated products that azeotropic backflow certain hour is discharged behind the moisture is directly carried out next step double esterification reaction.Avoid document described, adopted the purifying technique that dewaters of repeatedly solvent extraction, washing, needed to consume a large amount of solvents, reduced the input of solvent recuperation treatment process and extraction equipment, also reduced pollution.
Added solvent was made next step band aqua for the solvent of double esterification reaction system and double esterification reaction again when sulfonation reaction of the present invention finished.
In order to accelerate the process of double esterification reaction, added solvent was as the band aqua of double esterification reaction when present method was the end of employing sulfonation reaction.Solubilizing agent is made water-removal agent in addition, has also avoided the requirement of the described employing negative-pressure operation of document to equipment, has simplified technology.
Continuous generation along with product in the double esterification reaction process can make the system thickness, is difficult for stirring, and material is difficult for disperseing, and the influence reaction is carried out smoothly.Traditional method is a solubilizing agent or by improving the flowability that temperature of reaction improves reaction system.Added solvent was as the solvent of double esterification reaction when present method directly finished sulfonation reaction, double esterification reaction reacts the thickness of the system that prevented in the presence of this solvent, do not need other solubilizing agent and raising temperature of reaction, because the raising temperature not only consumes energy byproduct of reaction is increased, so present method by product is few, energy consumption is low.
All the time carry out under the azeotropic reflux temperature at the double esterification reaction in the presence of the solvent, for fast reaction speed, the present invention has also impelled the water that generates in the reaction to discharge smoothly by controlling quantity of reflux and the return velocity that oil bath temperature improves reaction system.Avoided adopting traditional technology to pressurize and improved the method for temperature of reaction.Reduced requirement, also simplified technology equipment.
Double esterification reaction is difficulty relatively, needs to use acid or alkali as catalyzer.Traditional technology generally adopts sulfuric acid, tosic acid etc., and shortcoming is strong to equipment corrosion, the waste water that side reaction is many and generation is a large amount of.As double esterification reaction catalyzer of the present invention, active high, cost is low with novel carbonyl solid acid for solid super acid catalyst cost height, this research, and side reaction is few, and is little to equipment corrosion, and catalyzer can be recycled.
The invention will be further described below in conjunction with embodiment.
Embodiment:
Single-esterification: in the four-hole boiling flask of being furnished with agitator, thermometer and reflux exchanger, add 4-methyl-2-amylalcohol, cis-butenedioic anhydride successively and account for the alkylsulphonic acid catalyzer of cis-butenedioic anhydride quality 1% in n (cis-butenedioic anhydride): n (4-methyl-2-amylalcohol)=1.05: 1.00 ratio (mol ratio), feed nitrogen, stir in the 10min and be warming up to 100 ℃; Keep this temperature and timing, insulation reaction time 60min.Sulfonation reaction: on same reaction unit, add the sulphonating agent aqueous solution of sodium bisulfite; the mol ratio of mono-esterification product and the contained sulfurous gas of sulphonating agent is 1.00: 1.10; this sulfonation reaction is under the atmosphere protection that nitrogen is arranged; being warmed up to 90 ℃ picks up counting; sulfonation reaction is under 90～95 ℃ of temperature; finish through the 180min reaction; sulfonated tail gas S02 absorbs with sig water (sodium hydroxide of 10%～20% weight concentration) and returns for sulfonation reaction; after sulfonation reaction finishes; on same reaction unit, add water trap, in m (toluene): m (sulfonated products)=0.5: 1 ratio (mass ratio) adding toluene.Heated and stirred, oil bath temperature are controlled at the system azeotropic were refluxed 1 hour, and moisture drains.Constantly tell the water that is generated during this time from water trap, refluxing toluene is gone into reaction system.Double esterification reaction: in same table apparatus, press n (cis-butenedioic anhydride): n (ethylene glycol)=1.00: 2.25 (mol ratio) and add ethylene glycol, the carbonyl solid acid catalyst that adds cis-butenedioic anhydride quality 3%, added toluene is made the band aqua when finishing with sulfonation reaction, heating, 190 ± 5 ℃ of control oil bath temperatures, in the reaction process, constantly tell the moisture that is generated from water trap, toluene returns into reaction system.Insulation reaction 300min does not have moisture to produce in the system, reaction finishes, and toluene no longer passes back into system, reclaims the toluene in the water trap.Product is cooled to below 60 ℃, is 7 ± 0.5 with the 30% aqueous sodium hydroxide solution pH value that neutralizes.
The reaction formula of above-mentioned single-esterification is:
The reaction formula of above-mentioned sulfonation reaction is:
The reaction formula of above-mentioned double esterification reaction is:
The physicochemical property such as the table 1 of ethylene glycol bis sulfo-succinic acid two (2-methyl amyl) ester sodium.
Table 1 surface property
Claims (7)
1. an ethylene glycol bis sulfo-succinic acid two (4-methyl 2-amyl group) ester sodium, it is characterized in that: its chemical structural formula is:
2. the production method of the described ethylene glycol bis sulfo-succinic acid two of claim 1 (4-methyl 2-amyl group) ester sodium is characterized in that: comprise the following steps:
(1) single-esterification: with cis-butenedioic anhydride and 4-methyl-2-amylalcohol reaction, form the mono-esterification product, reaction formula is:
(2) sulfonation reaction: mono-esterification product and sodium bisulfite reaction with step (1) obtains, form sulfonated products, its reaction formula is:
(3) sulfonated products and the glycol reaction that obtain of step (2) just obtains ethylene glycol bis sulfo-succinic acid two (4-methyl 2-amyl group) ester sodium, and reaction formula is:
3. the production method of ethylene glycol bis sulfo-succinic acid two according to claim 2 (4-methyl 2-amyl group) ester sodium is characterized in that: during single-esterification, be catalyzer with the alkylsulphonic acid catalyzer.
4. the production method of ethylene glycol bis sulfo-succinic acid two according to claim 2 (4-methyl 2-amyl group) ester sodium is characterized in that: sulfonation reaction is to carry out under the atmosphere protection of nitrogen.
5. the production method of ethylene glycol bis sulfo-succinic acid two according to claim 2 (4-methyl 2-amyl group) ester sodium is characterized in that: when sulfonation reaction finishes, also carry out branch water with toluene.
6. the production method of ethylene glycol bis sulfo-succinic acid two according to claim 2 (4-methyl 2-amyl group) ester sodium is characterized in that: add the carbonyl solid acid catalyst during double esterification reaction.
7. the production method of ethylene glycol bis sulfo-succinic acid two according to claim 5 (4-methyl 2-amyl group) ester sodium is characterized in that: during double esterification reaction, added toluene is as the band aqua when finishing with sulfonation reaction.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111995551A (en) * | 2020-09-01 | 2020-11-27 | 吉林大学 | Surface active material for efficiently solubilizing chlorinated hydrocarbon pollutants in underground water and synthetic method thereof |
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| 《化学世界》 20070731 李小芳等 Gemini表面活性剂--乙二醇双琥珀酸正辛醇双酯磺酸钠的合成与性能研究 第421－424页 1－7 , 第7期 * |
| 刘建华等: "磺基琥珀酸钠盐的合成研究", 《广东化工》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111995551A (en) * | 2020-09-01 | 2020-11-27 | 吉林大学 | Surface active material for efficiently solubilizing chlorinated hydrocarbon pollutants in underground water and synthetic method thereof |
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Application publication date: 20110420 |