CN101993905A - Method for separating crystalline maltitol through chromatograph - Google Patents
Method for separating crystalline maltitol through chromatograph Download PDFInfo
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- CN101993905A CN101993905A CN2009100176366A CN200910017636A CN101993905A CN 101993905 A CN101993905 A CN 101993905A CN 2009100176366 A CN2009100176366 A CN 2009100176366A CN 200910017636 A CN200910017636 A CN 200910017636A CN 101993905 A CN101993905 A CN 101993905A
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- maltitol
- chromatograph
- chromatographic separation
- mother liquid
- liquefaction
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Abstract
The invention relates to a method for separating crystalline maltitol through chromatograph, which comprises the following steps of: preparing maltitol by using starch milk as raw materials through liquefaction and saccharification by an enzymic method; separating, purifying, and carrying out hydrogenation to obtain high-concentration maltitol; repurifying, crystallizing, drying and packaging; back flowing partial crystalline mother liquid, and concentrating and crystallizing t to improve the crystallization yield; and discharging partial mother liquid out of the system to prevent the impurity accumulation. After the discharged mother liquid is subjected to ion exchange, the maltitol is separated and recovered through de-chromatograph, and the separated impurities are used as ordinary maltitol after being concentrated.
Description
Technical field
The present invention relates to biological field, particularly a kind of method of chromatographic separation crystal maltitol.
Background technology
Producing crystal maltitol is to make raw material with starch milk, through the enzyme process starch-splitting, obtains to contain the mixed solution of monobasic sugar, binary sugar (maltose), ternary sugar, quaternary sugar, five yuan of sugar.Other sugar all has bigger influence to the crystallization of binary sugar alcohol.Separation is purified and is obtained high-purity maltose, not only can reduce the hydrogenant hydrogen consumption, mainly is the feed liquid that can obtain crystallization requirement purity, and therefore separating purification is the key of technology.Existing separation method has chromatography and nanofiltration separation method, and chromatography requires the concentration of charging dry about 60%.
The maltose alcohol production method has spray-drying process and crystallization process, and the former product particle is thin, and impurity is many, and market price is low, and spray-dired energy consumption is big; The purity height of latter's crystalline product, the market price height, energy consumption is low.
This process using industrial chromatography tripping device separates the sugar that removes more than the binary, adopts chromatographic separation to reclaim the maltose alcohol of mother liquor, and obtains product with crystallization method.
Summary of the invention
The production method of crystal maltitol of the present invention is to be raw material with the starch milk, make maltose through the enzymatic liquefaction saccharification, after separating purification, hydrogenation obtains the maltose alcohol of high density, purify again post crystallization, drying, packing, the partial crystallization mother liquor is back to the condensing crystal operation, to improve crystallization yield, part discharge system prevents impurities accumulation.The mother liquor of discharging discolors and composes the Separation and Recovery maltose alcohol through after handing over, and the impurity of separating concentrates the back as common maltose alcohol.
Isolated ternary of maltose and above sugar are transformed syrupy product through decolouring, concentrate, filtering promptly in the acquisition.
Embodiment:
(1) adopt efficient Ye Huamei and the efficient hydrojet well heater of the U.S., can make liquefaction more thorough, not only shorten heated time, save steam, what is more important can be opened the secondary structure of starch molecule effectively, helps liquefaction, saccharification.
(2) syrup filtration employing is that flocculating aids is finished through vacuum suction filter with diatomite.
(3) continuously from handing over desalination, than conventional fixed bed ion-exchange unit higher working efficiency is arranged, resin consumption only be about the 1/4-1/2 of fixed bed, and wastewater flow rate only be its about 1/3, take up an area of also very for a short time, significantly reduction is invested and working cost.
(4) change the mode of operation of using the single-column chromatographic separation always, periodical operation is become operate continuously, make each section chromatographic column in running order all the time, improved the working efficiency of chromatographic column, reduce the consumption of eluent, also significantly reduced the fluctuation of the input and the quality product that human factor causes of personnel's work.Four-column type modified version ISMB The Application of Technology had both improved the quality of product, had also reduced production cost.
(5) wastewater membrane is handled.In the production process, regeneration of resin will produce the waste water that much contains inorganic salt, and this part waste water cannot directly discharge, in order to avoid environment is polluted, biochemical treatment is had any problem (lacking C, the utilization of N source confession microorganism) separately.This engineering utilization RO membrane technique is handled this part waste water, and it sees through liquid and can return as deionized water, and trapped fluid enters the biochemical treatment station with starch wastewater.
The secondary steam of the evaporation concentration in the production process and in the preface of handing over reclaims, contain sugar part, this part waste water is handled by the RO film, deionized water returns in the technology and uses, simultaneously waste water contain sugared recyclable, reduce raw material sugar and consume.
(6) whole-process automatic control.Technology chain of the present invention is longer, and the fluctuation of processing condition has a strong impact on generation to reaction process, and omnidistance enforcement of technology controlled automatically, reduce the human factor influence, guarantee that production process is in the optimised process reference mark all the time,, improved technical guarantee for improving the quality of products and yield.
Claims (3)
1. the method for a chromatographic separation crystal maltitol is characterized in that adopting the efficient hydrojet well heater of the efficient Ye Huamei and the U.S., can make liquefaction more thorough, more can open the secondary structure of starch molecule effectively, helps liquefaction, saccharification.
2. the method for a kind of chromatographic separation crystal maltitol as claimed in claim 1 is characterized in that it is that flocculating aids is finished through vacuum suction filter with diatomite that syrup filters employing.
3. the method for a kind of chromatographic separation crystal maltitol as claimed in claim 1 is characterized in that changing the mode of operation of using the single-column chromatographic separation always, and periodical operation is become operate continuously, makes each section chromatographic column in running order all the time.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100176366A CN101993905A (en) | 2009-08-13 | 2009-08-13 | Method for separating crystalline maltitol through chromatograph |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100176366A CN101993905A (en) | 2009-08-13 | 2009-08-13 | Method for separating crystalline maltitol through chromatograph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101993905A true CN101993905A (en) | 2011-03-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009100176366A Pending CN101993905A (en) | 2009-08-13 | 2009-08-13 | Method for separating crystalline maltitol through chromatograph |
Country Status (1)
| Country | Link |
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| CN (1) | CN101993905A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109734756A (en) * | 2019-02-28 | 2019-05-10 | 山东兆光色谱分离技术有限公司 | A kind of method of chromatographic isolation maltitol |
-
2009
- 2009-08-13 CN CN2009100176366A patent/CN101993905A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109734756A (en) * | 2019-02-28 | 2019-05-10 | 山东兆光色谱分离技术有限公司 | A kind of method of chromatographic isolation maltitol |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110330 |