CN101921929A - Oxygen-containing medical β-titanium alloy for orthopedic implants and preparation method thereof - Google Patents
Oxygen-containing medical β-titanium alloy for orthopedic implants and preparation method thereof Download PDFInfo
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- 229910045601 alloy Inorganic materials 0.000 title claims abstract description 58
- 239000000956 alloy Substances 0.000 title claims abstract description 58
- 229910001040 Beta-titanium Inorganic materials 0.000 title claims abstract description 26
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 26
- 239000001301 oxygen Substances 0.000 title claims abstract description 26
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 239000007943 implant Substances 0.000 title claims abstract description 9
- 230000000399 orthopedic effect Effects 0.000 title abstract description 3
- 229910001069 Ti alloy Inorganic materials 0.000 claims abstract description 22
- 239000004615 ingredient Substances 0.000 claims abstract description 18
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229910001362 Ta alloys Inorganic materials 0.000 claims abstract description 10
- 238000003723 Smelting Methods 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 6
- 238000002844 melting Methods 0.000 claims description 17
- 230000008018 melting Effects 0.000 claims description 17
- 239000010936 titanium Substances 0.000 claims description 16
- 238000005266 casting Methods 0.000 claims description 12
- 238000002513 implantation Methods 0.000 claims description 11
- 238000005275 alloying Methods 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 5
- 238000005096 rolling process Methods 0.000 claims description 4
- 238000007669 thermal treatment Methods 0.000 claims description 4
- 238000000137 annealing Methods 0.000 claims description 3
- 238000005098 hot rolling Methods 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000005482 strain hardening Methods 0.000 abstract 1
- 239000010955 niobium Substances 0.000 description 14
- 238000005260 corrosion Methods 0.000 description 11
- 239000000126 substance Substances 0.000 description 11
- 229910052715 tantalum Inorganic materials 0.000 description 10
- 229910052758 niobium Inorganic materials 0.000 description 9
- 229910052719 titanium Inorganic materials 0.000 description 9
- 229910052726 zirconium Inorganic materials 0.000 description 9
- 230000007797 corrosion Effects 0.000 description 8
- 239000000463 material Substances 0.000 description 7
- 210000000988 bone and bone Anatomy 0.000 description 5
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 4
- 229910000883 Ti6Al4V Inorganic materials 0.000 description 4
- 239000007769 metal material Substances 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 231100000331 toxic Toxicity 0.000 description 4
- 230000002588 toxic effect Effects 0.000 description 4
- 229910052720 vanadium Inorganic materials 0.000 description 4
- 229910000979 O alloy Inorganic materials 0.000 description 3
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 description 3
- 239000012567 medical material Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 3
- 231100000701 toxic element Toxicity 0.000 description 3
- 229910000599 Cr alloy Inorganic materials 0.000 description 2
- 229910011214 Ti—Mo Inorganic materials 0.000 description 2
- 229910052786 argon Inorganic materials 0.000 description 2
- 230000003013 cytotoxicity Effects 0.000 description 2
- 231100000135 cytotoxicity Toxicity 0.000 description 2
- 238000010891 electric arc Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- 229910052759 nickel Inorganic materials 0.000 description 2
- GUCVJGMIXFAOAE-UHFFFAOYSA-N niobium atom Chemical compound [Nb] GUCVJGMIXFAOAE-UHFFFAOYSA-N 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229910052718 tin Inorganic materials 0.000 description 2
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 2
- 229910052721 tungsten Inorganic materials 0.000 description 2
- 239000010937 tungsten Substances 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 229910000990 Ni alloy Inorganic materials 0.000 description 1
- 229910010413 TiO 2 Inorganic materials 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 229910000905 alloy phase Inorganic materials 0.000 description 1
- 229910000963 austenitic stainless steel Inorganic materials 0.000 description 1
- 239000003519 biomedical and dental material Substances 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 244000309464 bull Species 0.000 description 1
- 230000007541 cellular toxicity Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
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- 230000003446 memory effect Effects 0.000 description 1
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- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
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- 238000001304 sample melting Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- PMTRSEDNJGMXLN-UHFFFAOYSA-N titanium zirconium Chemical compound [Ti].[Zr] PMTRSEDNJGMXLN-UHFFFAOYSA-N 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 239000005418 vegetable material Substances 0.000 description 1
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- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
一种医疗器械技术领域的用于骨科植入的含氧医用β钛合金及其制备方法，通过将合金配料进行真空自耗熔炼处理得到Ti-Nb-Zr-Ta合金后，再经非自耗熔炼处理后依次进行热处理和热加工，实现医用β钛合金的制备，得到含氧医用β钛合金，其质量百分比为：氧元素0.13wt％-0.53wt％。所述钛合金的成分及质量百分比为：Ti60％、Nb35％、Zr3％以及Ta2％。本发明选取生物安全性元素，通过加入较高含量的β稳定元素使得合金具有很好的冷加工性能，通过向合金中增加氧元素的含量来强化合金，通过不同含量氧元素的添加来优化氧元素比例，使得合金具有较高强度，同时具有较低弹性模量。An oxygen-containing medical β-titanium alloy used for orthopedic implants in the technical field of medical devices and a preparation method thereof. The Ti-Nb-Zr-Ta alloy is obtained by vacuum consumable smelting of the alloy ingredients, and then non-consumable After the smelting treatment, heat treatment and heat processing are carried out sequentially to realize the preparation of the medical β titanium alloy, and obtain the oxygen-containing medical β titanium alloy, the mass percentage of which is: oxygen element 0.13wt%-0.53wt%. The composition and mass percentage of the titanium alloy are: Ti60%, Nb35%, Zr3% and Ta2%. The present invention selects biosafety elements, makes the alloy have good cold working performance by adding a relatively high content of β-stable elements, strengthens the alloy by increasing the content of oxygen element in the alloy, and optimizes the oxygen element by adding oxygen elements with different contents The proportion makes the alloy have higher strength and lower modulus of elasticity at the same time.
Description
Technical field
What the present invention relates to is material of a kind of medical equipment technical field and preparation method thereof, specifically is a kind of medicinal oxygen-containing beta titanium alloy that is used for the orthopaedics implantation and preparation method thereof.
Background technology
In current field of medical materials, being used in the orthopaedics made various joint prosthesises, artificial bone and various inside and outside fixed apparatus; The materials demand that being mainly used in the dentistry made artificial tooth, obturator, planting body, orthopedic wire and various assisting therapy devices is more and more.In all bio-medical materials.Metallic substance is used the earliest, and the application at present clinical is also still extensive.Being used for clinical metallic substance at first is the stainless steel with certain etch resistant properties, wherein the most commonly used is the 316L austenitic stainless steel, developed the Co-Cr alloy later on again, this series alloy has good erosion resistance and intensity in coenocorrelation, therefore is widely used in the bio-medical field.At the initial stage forties, Bothe etc. have delivered the article that reacts about between multiple metal planting body and the bone, subsequently titanium are introduced biomedical sector.They comprise several metals in the femur of titanium, stainless steel and Co-Cr alloy implantation mouse, found that no any untoward reaction between titanium and the bone, thereby have opened up titanium alloy in the New Times of giving birth to the body medical field.Because titanium alloy has advantages such as high biocompatibility, low density, low elastic modulus, high strength, anti-body fluid corrosion, is widely used in medical field.
(α, alpha+beta β), generally can roughly be divided into the three generations with the application and the development of biological medical titanium alloy according to the type of titanium alloy.The first-generation is representative with pure titanium and Ti-6Al-4V, and the ultralow gap of Ti-6Al-4V (ELI) alloy has better biocompatibility, and solidity to corrosion and mechanical property are most popular so far surgery embedded materials.The s-generation is to be the type alpha+beta alloy of representative with Ti-5Al-2.5Fe and Ti-6Al-7Nb, do not contain Ti-6Ai-7Nb and two kinds of alpha+beta titanium alloys of Ti-5Al-2.5Fe to the toxic element V of health, have with Ti-6Al-4V ELI alloy phase like mechanical property, also be widely used in surgical field.With respect to the Young's modulus of people's bone 10-30GPa, such titanium alloy has bigger Young's modulus, implants and causes " stress shielding " phenomenon easily.Therefore, exploitation has the developing direction that becomes the biological medical titanium alloy nineties than the third generation titanium alloy of low elastic modulus.Enter the initial stage nineties, Ti-Mo is that beta titanium alloy has obtained broad research as medical material.As Ti-12Mo-6Zr-2Fe, Ti-15Mo-5Zr-3Al and Ti-15Mo-3Nb-0.30 (21SRx) etc.Such alloy has higher tensile strength, fracture toughness property, better abrasion resistance properties, but the Young's modulus of this class alloy still is higher than the flexible bone modulus.Design and develop the emphasis that the beta-titanium alloy with lower Young's modulus becomes the medical titanium alloy developing material.Find that in the research of biological medical titanium alloy some metal ion meeting and human organ react, secular implanting can be caused toxic action to health.Therefore, reduce and avoid alloy element that the toxic action of health is seemed particularly important.
Find through retrieval prior art, Steinemann S.G, Corrosion of titanium and titaniumalloys for surgical implants.Titanium ' 84 Science and Technology, vol.2.Munich, Deutsche Gesellschaft Fur Metallkunde EV 1985,2:1373-1379. (surgery is implanted the erosion resistance research with titanium or titanium alloy) contrasted stainless steel, cobalt-chromium-molybdenum-nickelalloy, titanium, tantalum, zirconium, niobium, live body embedded material corrosive linear polarization results of study such as platinum, and provide the contrast of these data and experiment in vitro.The result shows that V, Ni, Co are biological toxic element, and titanium, tantalum, zirconium, elements such as niobium have good biological safety, is biological toxic element at the certain advantage of surgery vegetable material and V, Ni, Co.
Kawahara H, Cytotoxicity of implantable metals and alloys.Bull.Jpn.Inst.Met., 1992,31 (12): 1033-1039. (cytotoxicity of implant metallic substance) has put down in writing by the cell toxicity test of implant metallic substance is discovered, Al, Fe are to the toxic effect of human body., Al, Fe are to the toxic effect of human body.
Okazaki Y, Ito Y, Kyo K, Tateisi T, Corrosion resistance and corrosion fatiguestrength of new titanium alloys for medical implants without V and Al, Mater.Sci.Eng.A, 1996,213:138-147. do not put down in writing in (not containing the solidity to corrosion and the research of anti-corrosion fatigue strength of the novel implantation medical titanium alloy of V and Al element): show through a large amount of experiments, contrasted Ti-15Zr-4Nb-4Ta-0.2Pd-0.20-0.05N, Ti-15Sn-4Nb-2Ta-0.2Pd-0.20 alloy and low gap Ti-6A1-4V, the solidity to corrosion of Ti-6A1-2Nb-1Ta and pure titanium and anti-corrosion fatigue strength draw by Nb, Ta, elementary composition titanium alloy such as Zr and Sn has good solidity to corrosion and anti-corrosion fatigue strength.
In sum, thus the low elastic modulus beta-titanium alloy that contains elements such as Nb, Ta, Zr and Sn have bigger application potential.With Ti-Mo, Ti-Nb, Ti-Ta and Ti-Zr are that the beta-titanium alloy of matrix obtains extensive studies at present, other titanium alloys commonly used of comparing, and this class alloy combination can obtain low Young's modulus, perhaps has high intensity.Ti-Nb base alloy is the medical titanium alloy of the most potential exploitation use owing to have low Young's modulus and shape memory effect preferably.The meta titanium alloy of some Ti-Nb bases has obtained application, as Ti-13Nb-13Zr, and Ti-35Nb-5Ta-7Zr, Ti-29Nb-13Ta-4.6Zr, Ti-39Nb-5.1Ta-7.1Zr (TNTZ) and Ti-34Nb-9Zr-8Ta.These titanium alloys but cause alloy strength lower when obtaining low Young's modulus.The Young's modulus that has is higher, but the not enough 600MPa of the intensity of alloy, as Ti-35Nb-5Ta-7Zr.Outside the characteristics that satisfy the good biocompatibility of bio-medical material, also should make material have medium intensity and lower Young's modulus.In general, the tensile strength of material is greater than 650MPa, and Young's modulus can satisfy orthopaedics, the application in bio-medical fields such as dentistry below 70GPa.
Summary of the invention
The present invention is directed to the prior art above shortcomings, a kind of medicinal oxygen-containing beta titanium alloy that is used for the orthopaedics implantation and preparation method thereof is provided, the alloy safety non-toxic for preparing can be widely used in medical instruments fields such as orthopaedics, dentistry.
The present invention is achieved by the following technical solutions:
The present invention relates to a kind of medicinal oxygen-containing beta titanium alloy that orthopaedics is implanted that is used for, its mass percent is: oxygen element 0.13wt%-0.53wt%, the composition of described titanium alloy and mass percent are: Ti60%, Nb35%, Zr3% and Ta2%.
The present invention relates to the above-mentioned preparation method who is used for the medicinal oxygen-containing beta titanium alloy of orthopaedics implantation, by alloying ingredient is carried out vacuum consumable smelting handle obtain the Ti-Nb-Zr-Ta alloy after, after the non-consumable melting is handled, heat-treat successively and hot-work again, realize the preparation of medical beta-titanium alloy.
Described alloying ingredient is the Ti element of 60 weight parts, the Nb element of 35 weight parts, the Zr element of 3 weight parts and the Ta element of 2 weight parts.
Described vacuum consumable smelting is handled and is meant: after placing the vacuum consumable electrode arc furnace melt back to obtain ingot casting three times alloying ingredient, ingot casting is forged 950 ℃ of coggings, after through 780 ℃ of homogenizing annealing half an hour, obtain the Ti-Nb-Zr-Ta alloy.
Described non-consumable melting is handled and is meant: add TiO after the Ti-Nb-Zr-Ta alloy is cut into block sample
2Powder adopts vacuum non-consumable melting mode to prepare Ti-Nb-Zr-Ta-O button ingot.
Described vacuum non-consumable melting mode is meant: carry out hot rolling under 950 ℃ of environment, air cooling after 780 ℃ of solution treatment half an hour.
Described thermal treatment is meant: the alloy after the non-consumable melting is handled places air cooling after 780 ℃ of solution treatment half an hour.
Described hot-work is meant: adopt duo mill rolling after the alloy after the thermal treatment is placed 950 ℃ of half an hour, pass deformation rate is controlled at 5-15%, and rolling deformation is thickness 1.5-2.5mm, makes medical beta-titanium alloy.
The over-all properties of the Ti-Nb-Zr-Ta-O alloy of the different oxygen that melting obtains through the vacuum non-consumable improves significantly, the intensity of the Ti-Nb-Zr-Ta alloy of comparing, and the intensity of Ti-Nb-Zr-Ta-O alloy is significantly improved; The titanium alloy that the present invention prepares is chosen the biological safety element, make alloy have good cold-forming property by the beta stable element that adds high level, come reinforced alloys by the content that in alloy, increases oxygen element, optimize the oxygen element ratio by the interpolation of different content oxygen element, make alloy have higher-strength, have than low elastic modulus simultaneously.
Embodiment
Below embodiments of the invention are elaborated, present embodiment is being to implement under the prerequisite with the technical solution of the present invention, provided detailed embodiment and concrete operating process, but protection scope of the present invention is not limited to following embodiment.
Embodiment 1
Adopt vacuum non-consumable melting method to prepare the Ti-Nb-Zr-Ta-O alloy.The Ti-Nb-Zr-Ta alloy of vacuum consumable smelting is cut into block sample.Cut the 80g alloy block, add TiO
2Powder 0.27g.The weight percent of button ingot casting is: Ti:60%, Nb:35%, Zr:3%, Ta:2%, the melting in magnetic control tungsten electrode button electric arc furnace of O:0.13wt% raw material.Smelting furnace vacuum tightness is 6.6 * 10
-3Pa, the tungsten electrode lifting is driven by micromotor; Lighting arc method is the high-frequency spark scratch start, and electric arc is lighted the security device that the back cuts off high frequency automatically.The general work electric current is 700-800A, and maximum melting electric current is 1250A.In fusion process, use electromagnetic mixing apparatus, to guarantee that each component is fully reacted and melting is even.For guaranteeing the homogeneity of composition, after each sample melting, the remelting of overturning again, melt back four times.Be cast into the lath of 70mm * 30mm * 10mm at last.The square sample that melting is come out, surface quality is better, does not see big being mingled with and pore, and the sample of casting is rolled into the lath that thickness is 0.5mm at 950 ℃.Sample is 780 ℃ of solution treatment half an hour, and the chemical ingredients of sample is as shown in table 2.Cut into tension specimen with wire electric discharge, specimen size is shown in example 1.Recording the room temperature tensile performance data is:
Tensile strength: 771.62MPa, yield strength: 650.27MPa, Young's modulus: 58.97GPa, unit elongation: 9.75%.
Table 2Ti-35Nb-3Zr-2Ta-O (wt%) chemical ingredients
Embodiment 2
Other conditions add TiO with embodiment 1
2Powder 0.53g, the weight percent of button ingot casting is: Ti:65%, Nb:35%, Zr:3%, Ta:2%, the chemical ingredients of O:0.26wt% sample is as shown in table 3.Recording the room temperature tensile performance data is:
Tensile strength: 756.86MPa, yield strength: 558.33MPa, Young's modulus: 65.00GPa, unit elongation: 17.80%.
Table 3Ti-35Nb-3Zr-2Ta-O (wt%) chemical ingredients
Embodiment 3
Other conditions add TiO with embodiment 1
2Powder 0.80g, the weight percent of button ingot casting is: Ti:65%, Nb:35%, Zr:3%, Ta:2%, the chemical ingredients of O:0.40wt% sample is as shown in table 4.Recording the room temperature tensile performance data is:
Table 4Ti-35Nb-3Zr-2Ta-O (wt%) chemical ingredients
Embodiment 4
Other conditions add TiO with embodiment 1
2Powder 1.07g, the weight percent of button ingot casting is: Ti:65%, Nb:35%, Zr:3%, Ta:2%, the chemical ingredients of O:0.53% sample is as shown in table 5.Recording the room temperature tensile performance data is:
Tensile strength: 883.07MPa, yield strength: 726.00MPa, Young's modulus: 90.91Pa, unit elongation: 0.87%.
Table 5Ti-35Nb-3Zr-2Ta-O (wt%) chemical ingredients
Comparative Examples
Vacuum consumable smelting Ti-Nb-Zr-Ta alloy, Nb adds in master alloy TiNb (Nb content 50%wt) mode, and the Zr element adds in zirconium plate mode, and element T a adds in tantalum plate mode, adopts the one-level titanium sponge.Adopt argon arc welding to be connected at the electrode that suppresses with supporting electrode.For guarantee the ingot casting chemical ingredients evenly, ingot casting remelting three times at least.A melted ingot is used argon arc welding and supporting electrode seam after machining, again in the vacuum consumable electrode arc furnace melting.With alloy melt back three times in vacuum consumable electrode arc furnace after the proportioning in proportion, guarantee that composition is even.Ingot casting forges 950 ℃ of coggings, is swaged into the square billet of 180mm * 70mm * 30mm.After through 780 ℃ of homogenizing annealing half an hour, air cooling makes this alloy.The chemical ingredients of alloy is as shown in table 1.Be cut into tension specimen with line, and with abrasive paper for metallograph with surface grinding to eliminate surface imperfection.Tension specimen gauge length segment length is 20mm, and thickness is 1.5mm.Draw speed is 1.5 * 10-4s
-1, record alloy at room temperature tensile mechanical properties numerical value and be:
Tensile strength: 537.56MPa, yield strength: 325.39MPa, Young's modulus: 56.50GPa, unit elongation: 17.74%.
Table 1Ti-35Nb-3Zr-2Ta (wt%) chemical ingredients
Claims (8)
1. one kind is used for the medicinal oxygen-containing beta titanium alloy that orthopaedics is implanted, and it is characterized in that its mass percent is: oxygen element 0.13wt%-0.53wt%, the composition of described titanium alloy and mass percent are: Ti60%, Nb35%, Zr3% and Ta2%.
2. the preparation method who is used for the medicinal oxygen-containing beta titanium alloy of orthopaedics implantation according to claim 1, it is characterized in that, by alloying ingredient is carried out vacuum consumable smelting handle obtain the Ti-Nb-Zr-Ta alloy after, after the non-consumable melting is handled, heat-treat successively and hot-work again, realize the preparation of medical beta-titanium alloy.
3. the preparation method who is used for the medicinal oxygen-containing beta titanium alloy of orthopaedics implantation according to claim 2 is characterized in that described alloying ingredient is the Ti element of 60 weight parts, the Nb element of 35 weight parts, the Zr element of 3 weight parts and the Ta element of 2 weight parts.
4. the preparation method who is used for the medicinal oxygen-containing beta titanium alloy of orthopaedics implantation according to claim 2, it is characterized in that, described vacuum consumable smelting is handled and is meant: after placing the vacuum consumable electrode arc furnace melt back to obtain ingot casting three times alloying ingredient, ingot casting is forged 950 ℃ of coggings, after through 780 ℃ of homogenizing annealing half an hour, obtain the Ti-Nb-Zr-Ta alloy.
5. the preparation method who is used for the medicinal oxygen-containing beta titanium alloy of orthopaedics implantation according to claim 2 is characterized in that described non-consumable melting is handled and is meant: add TiO after the Ti-Nb-Zr-Ta alloy is cut into block sample
2Powder adopts vacuum non-consumable melting mode to prepare Ti-Nb-Zr-Ta-O button ingot.
6. the preparation method who is used for the medicinal oxygen-containing beta titanium alloy that orthopaedics implants according to claim 5 is characterized in that described vacuum non-consumable melting mode is meant: carry out hot rolling under 950 ℃ of environment, air cooling after 780 ℃ of solution treatment half an hour.
7. the preparation method who is used for the medicinal oxygen-containing beta titanium alloy that orthopaedics implants according to claim 2 is characterized in that described thermal treatment is meant: the alloy after the non-consumable melting is handled places air cooling after 780 ℃ of solution treatment half an hour.
8. the preparation method who is used for the medicinal oxygen-containing beta titanium alloy of orthopaedics implantation according to claim 2, it is characterized in that, described hot-work is meant: adopt duo mill rolling after the alloy after the thermal treatment is placed 950 ℃ of half an hour, pass deformation rate is controlled at 5-15%, rolling deformation is thickness 1.5-2.5mm, makes medical beta-titanium alloy.
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| CN114272442A (en) * | 2013-06-14 | 2022-04-05 | R + K Cad / Cam 技术有限两合公司 | Production of a semi-finished product for an implant based on plastic |
| CN115003344A (en) * | 2020-01-22 | 2022-09-02 | 华沙整形外科股份有限公司 | High modulus alloy for medical devices |
| CN118989033A (en) * | 2024-10-22 | 2024-11-22 | 上海理工大学 | Alloy wire suitable for oral implant and preparation method thereof |
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| CN102660737A (en) * | 2012-05-31 | 2012-09-12 | 西北有色金属研究院 | TiNb-alloy surface biological activating treatment method |
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| CN106148759A (en) * | 2015-04-23 | 2016-11-23 | 中国科学院金属研究所 | Have and facilitate bone and the medical titanium alloy of revascularization biological function and preparation thereof |
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| CN107034383A (en) * | 2017-03-27 | 2017-08-11 | 华南理工大学 | One kind is containing high-strength low mould beta titanium alloys of Si and preparation method and application |
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| CN107217221A (en) * | 2017-05-22 | 2017-09-29 | 西部超导材料科技股份有限公司 | A kind of preparation method of high uniform Ti 15Mo titanium alloy bar stocks |
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| CN110201237B (en) * | 2019-07-05 | 2021-09-07 | 中南大学 | A kind of antibacterial and bone-promoting rubidium-titanium-tantalum composite material and its preparation method and application |
| CN110201237A (en) * | 2019-07-05 | 2019-09-06 | 中南大学 | A kind of antibacterial facilitates bone titanium containing rubidium tantalum composite material and preparation method and application |
| CN115003344A (en) * | 2020-01-22 | 2022-09-02 | 华沙整形外科股份有限公司 | High modulus alloy for medical devices |
| US12005155B2 (en) | 2020-01-22 | 2024-06-11 | Warsaw Orthopedic, Inc. | High-modulus alloy for medical devices |
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