CN101869741A - Multipurpose medical light source system - Google Patents
Multipurpose medical light source system Download PDFInfo
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- CN101869741A CN101869741A CN 201010215182 CN201010215182A CN101869741A CN 101869741 A CN101869741 A CN 101869741A CN 201010215182 CN201010215182 CN 201010215182 CN 201010215182 A CN201010215182 A CN 201010215182A CN 101869741 A CN101869741 A CN 101869741A
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Abstract
The invention discloses a multipurpose medical light source system. The medical light source system comprises a core control device, an optical convergence component, a combiner, a multiple wavelength LED light source, an execution mechanism and a selective light source, wherein the multiple wavelength LED light source, the execution mechanism and the selective light source are controlled by the core control device, and the multiple wavelength LED light source comprises a fixed plate and at least one LED light-emitting substrate fixed on the fixed plate; the execution mechanism drives the fixed plate to move under the control of the core control device so that the central point of the emitting light of the LED light-emitting substrate moves to an incident light axial line of the optical convergence component; light beams of the LED light-emitting substrate are aligned and output to the input end of the combiner through the shaping and the focusing of the optical convergence component, and the selective light source is connected with the other end of the combiner. The light emitted by the LED light-emitting substrate and the selective light source can be output in time share through the combiner, or a combined beam formed by the light emitted by the LED light-emitting substrate and the selective light source can be output to really realize the multipurpose of one machine.
Description
Technical field
The present invention relates to medical instruments field, particularly a kind of multipurpose LED light-source system.
Background technology
Treatment and the diagnostic mode of light power for adopting light and photosensitizer drug to combine, its in treatment and diagnosis body cavity or the tumor and the range of application aspect the non-tumor disease of body surface more and more wider.A large amount of experimentation and clinical practices prove that photodynamic therapy is having broad application prospects aspect treatment, the diagnosis.
(photodynamic therapy is a kind of under aerobic conditions PDT) to photodynamic therapy, by the new method of photosensitizer treatment tumor in the specific wavelength optical excitation target cell.Its principle is, photosensitizer produces reactive oxygen species (reactiveoxygen species, ROS) coup injury tumor cell, and the impaired cancerous tissue blood perfusion that causes of blood capillary is reduced, and then cause tumor cell generation apoptosis or necrosis.Therefore, in photodynamic therapy, need the treatment light source that excites photosensitizer of specific wavelength.
(Photodynamic Diagnosis is that the characteristics of utilizing photosensitizer can send fluorescence under the rayed of specific wavelength are carried out PD) to light power fluorescence diagnosis.Its principle is, because tumor tissues has different biochemical metabolism characteristics with normal structure, and the high absorption of tumor tissues, low metabolism, after a period of time, photosensitizer can be deposited in the tumor tissues.Photosensitizer is under the irradiation of the light source of specific wavelength, and the reaction of a series of photochemical reactions and photobiology takes place photosensitizer, launches the fluorescence of specific wavelength, in endoscope's fluoroscopic image acquisition system, can be observed tumor and normal structure makes a distinction.In light power fluorescence diagnosis location, need select the excitation source of different wave length according to different photosensitizer.
When adopting photodynamic therapy to carry out interior therapeutic and diagnosis, generally need the configuration endoscopic apparatus, endoscopic apparatus then needs light source to throw light on.At present, the illumination for endoscope light source can be divided into two big classes by the difference of selecting luminescent device for use, one class is a luminescent device with heat radiation electric light source (as halogen tungsten lamp, fill the xenon halogen tungsten lamp), another kind of is luminescent device with glow discharge spot lamp (as xenon lamp, various metal halide lamp) then, and this two classes light source respectively has suitable application area.
In sum, when the treatment tumor adopts photodynamic therapy on clinical medicine, follow the means of light power fluorescence diagnosis simultaneously as diagnosis, location, observation.Present medical light source is independently light source, therefore, if in the seance process, when needing comprehensively to use above-mentioned treatment light source, excitation source and lighting source, the doctor need treat the period in difference needed light source is connected on the suitable interface, and this not only is not easy to doctor's operation, seriality that can not the strict guarantee treatment, thereby prolonged treatment time, also probably influenced therapeutic effect.The medical light source that if can export multi-wavelength on an equipment is applied to medical field, satisfies above-mentioned various demand, then will bring great convenience and preferable treatment, diagnosis effect to practical application light power diagnosis and treatment.
Summary of the invention
The objective of the invention is to solve problems of the prior art, a kind of photodynamic therapy system that has sight glass shooting and fluorescence diagnosis function at least is provided.
Technical scheme of the present invention is: a kind of multipurpose medical light source system, comprise core control devices, and optical focus assembly and bundling device, and be controlled by multi-wavelength LED light source, the actuator of described core control devices and can select light source; Described multi-wavelength LED light source comprises fixing head and the LED of a slice at least light-emitting substrate that is fixed on the fixing head; Described actuator drives the fixing head motion under the control of core control devices, the emission light center point of the LED light-emitting substrate on the described fixing head is moved on the incident illumination axis of described optical focus assembly; The shaping of the light beam process optical focus assembly of LED light-emitting substrate and the input that focussed collimated outputs to described bundling device; The described light source of selecting links to each other with another input of bundling device.
Preferably, the described light source of selecting is endoscope illuminator or LASER Light Source.
Preferably, described optical focus assembly comprises first optical lens, second optical lens, focussed collimated lens and heat shield, the light beam that described LED light-emitting substrate sends passes through heat shield, in turn through the first optical lens shaping, focus on the focussed collimated lens through second optical lens, the line focus collimating lens outputs to an input of bundling device.
Preferably, described multi-wavelength LED light source also comprises the LED chiller that is controlled by core control devices, described LED chiller comprises thermoelectric refrigerator, temperature sensor and radiator, the cold junction of described thermoelectric refrigerator is affixed on the back side of fixing head, described LED light-emitting substrate all is fixed in the front of fixing head, and the hot junction of described thermoelectric refrigerator links to each other with radiator; The temperature of fixing head is gathered in described temperature sensor, and the temperature signal that collects is sent to described core control devices.
Described LED light-emitting substrate perhaps is made up of the led chip array of several identical wavelength or different wave length single led chip; The wave-length coverage of described led chip is 375nm～2200nm, and perhaps described led chip is that colour temperature is the White-light LED chip of 6000-6500k.
Preferably, described core control devices comprises controller and the thermostatic control module that is connected with its communication, described temperature sensor is sent to described controller with the temperature signal of gathering, and described controller changes the output of LED chiller by the thermostatic control module according to described temperature signal.
Preferably, described LED light-emitting substrate all is fixed on the front of fixing head 11, and described optical focus assembly is towards the front of fixing head, and makes the positive vertical of its incident illumination axis and fixing head.
Preferably, the emission light center point of described plurality of LED luminous substrate all is positioned on the same circumference on the front of fixing head, and the circumference at the described emission light center point of the incident illumination axis place of described optical focus assembly intersects; Described actuator can drive fixing head and rotate around its central shaft of crossing the center of circle of described emission light center point place circumference.
Preferably, two motions are finished in described actuator, and the reference coordinate axle of described two motions is two coordinate axes X, Y that are perpendicular to one another on the front of fixing head, and described actuator can drive fixing head and carry out resultant motion on two.
Preferably, described core control devices comprises controller and the communication module that is used to make controller and host computer carry out communication.
The invention has the beneficial effects as follows: multipurpose medical light source system of the present invention can use separately, can timesharing provides a kind of led light source of wavelength by the multi-wavelength LED light source, and this light source can be used as the excitation source that is used for the fluorescence excitation reaction generally speaking; Operator or host computer are by the controlled selection of communication module, core control devices can drive the motion of multi-wavelength LED light source according to the predeterminable level control executing mechanism, and then will move on the incident illumination axis of described optical focus assembly with the emission light center point of the LED light-emitting substrate of the selected wavelength that is complementary, in addition, for by photodynamic therapy treatment disease the time, the LED light-emitting substrate of multi-wavelength LED light source also can provide the treatment light source that carries out optical dynamic therapy;
In addition, the light source that multipurpose medical light source system selectively provides by the multi-wavelength LED light source and can select light source, the described light source of selecting is selected endoscope's cold light source or LASER Light Source for use at this, can provide lighting source by endoscope's cold light source, LASER Light Source then can participate in OPK treatment and diagnosis;
Moreover, at the multi-wavelength LED light source with can select light source to export simultaneously the time, also exportable LED light-emitting substrate of bundling device and LASER Light Source close bundle, form the light of another kind of wavelength and power, therefore, multipurpose medical light source system of the present invention can provide multiple light source configuration, and the doctor can finish various associative operations incessantly, for the persistence for the treatment of provides reliable assurance;
At last, described multipurpose medical light source system can cooperate uses together such as optical power therapentic equipment, and its core control devices can be carried out communication with host computer, receives higher level's instruction, cooperates optical power therapentic equipment to finish fluorescence diagnosis or treatment and illumination.
Description of drawings
The structural representation of Fig. 1 multipurpose medical light source system of the present invention;
Fig. 2 a is a kind of embodiment of multi-wavelength LED light source shown in Figure 1;
Fig. 2 b is the another kind of embodiment of multi-wavelength LED light source shown in Figure 1;
Fig. 3 is the structural representation of optical focus assembly shown in Figure 1;
Fig. 4 is the structural representation of core control devices shown in Figure 1.
The specific embodiment
The invention will be further described below in conjunction with accompanying drawing.
As shown in Figure 1, described multipurpose medical light source system comprises core control devices 50, multi-wavelength LED light source 10, actuator 21, optical focus assembly 30, bundling device 60 and can select light source 40.Described multi-wavelength LED light source 10 comprises fixing head 11 and the LED of a slice at least light-emitting substrate 12 that is fixed on the fixing head 11, every LED light-emitting substrate 12 can be packaged with single led chip, also can form by the led chip array of several identical wavelength or different wave length, the wave-length coverage of described led chip is typically chosen in 375nm～2200nm, described led chip also can be that colour temperature is the White-light LED chip of 6000-6500k, at this, the LED light-emitting substrate 12 of various wavelength forms can be provided according to demand, and LED light-emitting substrate 12 is arranged on fixing head 11 in some way.Described actuator 21 can drive fixing head 11 motions, the emission light center point of the arbitrary LED light-emitting substrate 12 on the fixing head 11 is moved on the incident illumination axis of described optical focus assembly 30, and the light beam of LED light-emitting substrate 12 outputs to described bundling device 60 through the shaping and the focussed collimated of optical focus assembly 30.
The described light source 40 of selecting can be endoscope's cold light source or LASER Light Source, at this, can select according to the actual requirements, the outfan of described optical focus assembly 30 links to each other with an input of bundling device 60, the described light source of selecting links to each other with another input of bundling device 60, and the outfan of bundling device 60 can connect the carrier of transmission light such as optical fiber or light guide bundles by adapter 70.Therefore, but export the light that a certain LED light-emitting substrate 12 sends and can select light source 40, perhaps export light that a certain LED light-emitting substrate 12 sends and can select the formed bundle that closes of light source through described bundling device 60 timesharing.
As shown in Figure 3, described optical focus assembly 30, comprise first optical lens 32, second optical lens 33, focussed collimated lens 34 and heat shield 31, wherein, the light beam that described LED light-emitting substrate 12 sends is by heat shield 31, through 32 shapings of first optical lens, focus on focussed collimated lens 34 through second optical lens 33 in turn, line focus collimating lens 34 outputs to bundling device 60.
The described light source 40 of selecting is controlled by core control devices 50, and described core control devices 50 drives multi-wavelength LED light source 10 by driving device 22 control executing mechanism 21 and moves to the desired position.In the present embodiment, the LED light-emitting substrate 12 of multi-disc different wave length all is fixed on the front of fixing head 11, described optical focus assembly 30 is towards the front of fixing head 11, and make the positive vertical of its incident illumination axis and fixing head 11, like this, as long as actuator 21 drive fixing heads 11 move in the plane at its place the emission light center point of the arbitrary LED light-emitting substrate 12 on it is moved on the incident illumination axis of described optical focus assembly 30.
For LED light-emitting substrate 12 can be operated under the temperature constant state as far as possible, described multi-wavelength LED light source 10 also comprises the LED chiller 13 that is packed on the fixing head 11, in the present embodiment, all LED light-emitting substrates 12 all are fixed on the front of fixing head 11, and described LED chiller 13 then is packed on the back side of fixing head 11.Described LED chiller 13 can comprise the radiator of thermoelectric refrigerator, temperature sensor and band radiator fan, the cold junction of described thermoelectric refrigerator is affixed on the back side of fixing head 11, the hot junction of described thermoelectric refrigerator links to each other with radiator, and then the heat that the hot junction produced of thermoelectric refrigerator is shed by air cooling way, described temperature sensor can detect the temperature of fixing head 11 in real time.
As shown in Figure 4, described core control devices 50 can comprise controller 51 and the communication module 52, thermostatic control module 53 and the constant current control module 54 that all are connected with described controller communication, and outside host computer can instruct transmission by communication module 52 and controller 51.The temperature sensor of described LED chiller 13 is sent to described controller 51 with the temperature signal of gathering and compares with the reference temperature value of presetting, controller 51 changes the output of LED chiller 13 by described thermostatic control module 53 according to result relatively, and then can make the temperature of fixing head 11, be the temperature of multi-wavelength LED light source 10, keep constant.At this, described controller 51 also can be sent to host computer by communication module 52 with comparative result, assigns control instruction at thermostatic control module 53 by described host computer to controller 51.
Described constant current control module 54 can be gathered the current signal of driving LED light-emitting substrate 12, and this current signal is delivered to controller 51, described controller 51 compares the instantaneous value of the current signal that receives and default reference current value, and according to the electric current of comparative result, and then make its operating current keep constant by constant current control module 54 change driving LED light-emitting substrates 12.At this, described controller 51 also can be sent to host computer by communication module 52 with comparative result, assigns control instruction at constant current control module 54 by described host computer to controller 51.
In addition, can select the action of light source 40 by described controller 51 controls.
If plurality of LED luminous substrate 12 is arranged on the front of fixing head 11, then described actuator 21 should be finished two motions, wherein, the reference coordinate axle of two motions is two coordinate axes X, Y that are perpendicular to one another on the front of fixing head 11, actuator 21 drives the resultant motion that fixing head 11 carries out on two, and resultant motion can be finished by the drive mechanism that two actuating motors drive separately.In the embodiment shown in Fig. 2 b, plurality of LED luminous substrate 12 is the matrix form of rule to be arranged, and the core control devices that arrangement is beneficial to 50 of rule is optimized the movement locus of actuator.A kind of embodiment as this kind embodiment, described fixing head 11 adopts square, be fixed with the LED light-emitting substrate 12 of four different wave lengths on it, the wavelength of encapsulated LED chip is respectively purple light 375nm, blue light 470nm, HONGGUANG 630nm and HONGGUANG 670nm on four LED light-emitting substrates 12, peak power is 10～100W, makes multi-wavelength LED light source 10 that the led light source of four kinds of different wave lengths can be provided.If can select light source 40 to be endoscope's cold light source, multipurpose medical light source system then of the present invention then can be selected timesharing output purple light 375nm, blue light 470nm, HONGGUANG 630nm, HONGGUANG 670nm or endoscope's cold light source.
For the ease of realizing the motor control of multi-wavelength LED light source 10, described plurality of LED luminous substrate 12 can adopt the arrangement mode shown in Fig. 2 a, be that the emission light center point of plurality of LED luminous substrate 12 all is positioned on the same circumference on the front of fixing head 11, and the incident illumination axis of optical focus assembly 30 and fixing head 11 are vertical and intersect with the circumference at the emission light center point place of LED light-emitting substrate 12.So, rotate around its central shaft of crossing the center of circle of described emission light center point place circumference, the LED light-emitting substrate 12 of arbitrary required wavelength can be turned on the incident illumination axis of optical focus assembly 30 as long as actuator 21 drives fixing head 11.Therefore, in this embodiment, described actuator can comprise an actuating motor, as motor.A kind of embodiment as this kind embodiment, shown in Fig. 2 a, described fixing head 11 also adopts circular, be fixed with the LED light-emitting substrate 12 of five different wave lengths on it, the wavelength of encapsulated LED chip is respectively blue light 405nm on five LED light-emitting substrates 12, HONGGUANG 630nm, HONGGUANG 670nm, green glow 532nm and near infrared light 780nm, peak power is 5～50W, make multi-wavelength LED light source 10 that the led light source of five kinds of different wave lengths can be provided, described led light source can be used as excitation source or the treatment light source that is used for fluorescence excitation, can drive fixing head 11 by the described actuator of core control devices 50 controls according to employed certain wavelength light source in use the LED light-emitting substrate 12 that matches is moved on the corresponding position.If can select light source 40 to be endoscope's cold light source, multipurpose medical light source system then of the present invention then can be selected timesharing output blue light 405nm, HONGGUANG 630nm, HONGGUANG 670nm, green glow 532nm, near-infrared 780nm or endoscope's cold light source.
Only being preferred embodiment of the present invention in sum, is not to be used for limiting practical range of the present invention.Be that all equivalences of doing according to the content of the present patent application claim change and modification, all should belong to technology category of the present invention.
Claims (10)
1. multipurpose medical light source system is characterized in that: comprise core control devices, and optical focus assembly and bundling device, and be controlled by multi-wavelength LED light source, the actuator of described core control devices and can select light source; Described multi-wavelength LED light source comprises fixing head and the LED of a slice at least light-emitting substrate that is fixed on the fixing head; Described actuator drives the fixing head motion under the control of core control devices, the emission light center point of the LED light-emitting substrate on the described fixing head is moved on the incident illumination axis of described optical focus assembly; The shaping of the light beam process optical focus assembly of LED light-emitting substrate and the input that focussed collimated outputs to described bundling device; The described light source of selecting links to each other with another input of bundling device.
2. multipurpose medical light source system according to claim 1 is characterized in that: the described light source of selecting is endoscope illuminator or LASER Light Source.
3. multipurpose medical light source system according to claim 1, it is characterized in that: described optical focus assembly comprises first optical lens, second optical lens, focussed collimated lens and heat shield, the light beam that described LED light-emitting substrate sends passes through heat shield, in turn through the first optical lens shaping, focus on the focussed collimated lens through second optical lens, the line focus collimating lens outputs to an input of bundling device.
4. multipurpose medical light source system according to claim 1 is characterized in that: described LED light-emitting substrate perhaps is made up of the led chip array of several identical wavelength or different wave length single led chip; The wave-length coverage of described led chip is 375nm～2200nm, and perhaps described led chip is that colour temperature is the White-light LED chip of 6000-6500k.
5. multipurpose medical light source system according to claim 1, it is characterized in that: described multi-wavelength LED light source also comprises the LED chiller that is controlled by core control devices, described LED chiller comprises thermoelectric refrigerator, temperature sensor and radiator, the cold junction of described thermoelectric refrigerator is affixed on the back side of fixing head, described LED light-emitting substrate all is fixed in the front of fixing head, and the hot junction of described thermoelectric refrigerator links to each other with radiator; The temperature of fixing head is gathered in described temperature sensor, and the temperature signal that collects is sent to described core control devices.
6. multipurpose medical light source system according to claim 5, it is characterized in that: described core control devices comprises controller and the thermostatic control module that is connected with its communication, described temperature sensor is sent to described controller with the temperature signal of gathering, and described controller changes the output of LED chiller by the thermostatic control module according to described temperature signal.
7. according to each described multipurpose medical light source system in the claim 1 to 6, it is characterized in that: described LED light-emitting substrate all is fixed on the front of fixing head, described optical focus assembly is towards the front of fixing head, and makes the positive vertical of its incident illumination axis and fixing head.
8. multipurpose medical light source system according to claim 7, it is characterized in that: the emission light center point of described plurality of LED luminous substrate all is positioned on the same circumference on the front of fixing head, and the circumference at the described emission light center point of the incident illumination axis place of described optical focus assembly intersects; Described actuator can drive fixing head and rotate around its central shaft of crossing the center of circle of described emission light center point place circumference.
9. multipurpose medical light source system according to claim 7, it is characterized in that: two motions are finished in described actuator, the reference coordinate axle of described two motions is two coordinate axes X, Y that are perpendicular to one another on the front of fixing head, and described actuator can drive fixing head and carry out resultant motion on two.
10. according to each described multipurpose medical light source system in the claim 1 to 6, it is characterized in that: described core control devices comprises controller and the communication module that is used to make controller and host computer carry out communication.
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| CN102654455A (en) * | 2012-04-12 | 2012-09-05 | 安徽皖仪科技股份有限公司 | Laser gas analyzer for multicomponent multiplexing measurement |
| CN104146711A (en) * | 2014-08-01 | 2014-11-19 | 深圳市开立科技有限公司 | Endoscope based lesion size measurement method and system |
| CN105030253A (en) * | 2015-06-29 | 2015-11-11 | 武汉一海数字工程有限公司 | Multi-wavelength diagnosis light source for mammary gland |
| CN108056810A (en) * | 2016-11-08 | 2018-05-22 | 高雄医学大学 | A kind of alignment system and method for non-intrusion type locking bone |
| CN108618743A (en) * | 2018-07-16 | 2018-10-09 | 鹰利视医疗科技有限公司 | A kind of Multipurpose endoscope light source |
| CN109140256A (en) * | 2018-09-04 | 2019-01-04 | 深圳市卡普瑞环境科技有限公司 | A kind of constant temperature light source |
| CN111249625A (en) * | 2020-01-21 | 2020-06-09 | 北京泓业致联科技有限公司 | Medical light source device and system |
| CN111358438A (en) * | 2020-03-20 | 2020-07-03 | 北京泓业致联科技有限公司 | Multi-wavelength laser diagnostic device |
| WO2024058047A1 (en) * | 2022-09-16 | 2024-03-21 | ソニーグループ株式会社 | Light source device and medical observation system |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102654455A (en) * | 2012-04-12 | 2012-09-05 | 安徽皖仪科技股份有限公司 | Laser gas analyzer for multicomponent multiplexing measurement |
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| CN108056810A (en) * | 2016-11-08 | 2018-05-22 | 高雄医学大学 | A kind of alignment system and method for non-intrusion type locking bone |
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| WO2024058047A1 (en) * | 2022-09-16 | 2024-03-21 | ソニーグループ株式会社 | Light source device and medical observation system |
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| CN101869741B (en) | 2011-11-09 |
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