CN101843563B

CN101843563B - Whitening toothpaste composite

Info

Publication number: CN101843563B
Application number: CN2010101732672A
Authority: CN
Inventors: 李少君; 张宏
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-05-11
Filing date: 2010-05-11
Publication date: 2012-06-27
Anticipated expiration: 2030-05-11
Also published as: CN101843563A

Abstract

The invention discloses a whitening toothpaste composite, belonging to the technical field of oral care preparations. The composite comprises the following components: whitening ingredients, a wetting agent, a cleanser, a stabilizer, an abrasive, a binder, xylitol, a flavoring agent and deionized water. Teeth stains can be gradually cleared away by using the whitening toothpaste composite in the invention for brushing regularly. Compared with the prior art, the whitening toothpaste composite in the invention has good stability, and after being stored for 6 months, the activated energy of the composite can reach above 91%, and the volume has no obvious change; and the composite is quite stable in the processes of expectant packaging, storage and transportation, marketing and using.

Description

Whitening toothpaste composite

Technical field

The invention belongs to the preparing technical field of oral cavity health preparation, particularly relating to a kind of is the whitening toothpaste composite of effective ingredient with the peroxide.Often use whitening toothpaste composite of the present invention to brush teeth, can remove teeth stains gradually.

Background technology

Current society, People more and more is paid close attention to the oral hygiene of oneself with healthy, has the pure white tooth of a bite more to become the target that many people pursue.How safe and effective removing teeth stains also becomes the problem that people pay close attention to naturally.Changes in tooth color is divided into endogenous changes in tooth color and external source tooth property changes in tooth color; The endogenous color of teeth is because tooth nerve injury, aging or such as antibiotic excessive uses such as tetracyclines, exogenous changes in tooth color is because residues such as nicotine of Nicotiana tabacum L. or tar, coffee, tea are deposited on dental surface.Since U.S. odontologist in 1981 was used to hydrogen peroxide to remove teeth stains for the first time, peroxide was cleared into branch with the standard mottle that its obvious effects and safety become American-European dental clinic.Peroxide is added the toothpaste of processing Magnesium Ascorbylphosphate in the toothpaste; American-European countries did some with the research institution of China and attempted, but because the unstability of peroxide makes the prepared toothpaste life-span shorter; Generally in three months, promptly can lose efficacy, even booster can take place.In order to prevent the decomposition of peroxide, the someone has studied a kind of " dual component tooth whitening dentifrice " (Chinese patent, 1207669).This is invented disclosed compositions and comprises first component that contains peroxide and second component that contains abrasive material, abrasive material and peroxide incompatible, and first component and the packing separately of second component, thus reach the purpose that prevents peroxide breakdown.But to need oneself to allocate again real genus inconvenience in use as a kind of daily toothpaste.There also have research that peroxide is carried out to be encapsulated, directly mix with other group then, but this just makes the peroxide release onset time depend on the dissolved time of capsule material.Therefore, how research is a kind of can and can keep its stable formulation of tooth-paste to be only the key of dealing with problems with peroxide compatible.

Summary of the invention

The invention provides a kind of is the whitening toothpaste composite of effective ingredient with the peroxide, said composition quite stable all in the packing, accumulating, sale, use of expection.Often use whitening toothpaste composite of the present invention to brush teeth, can remove teeth stains gradually.

Compositions of the present invention comprises whitening composition, wetting agent, cleaning agent, stabilizing agent, abrasive, binding agent, xylitol, flavour enhancer and deionized water, and concrete component and content are following:

1) 1%-20% whitening composition, preferred 2%-10%, whitening composition is one or more in hydrogen peroxide, percarbamide (claiming urea peroxide again), SODIUM PERCARBONATE, the percarbonic acid calcium;

2) wetting agent of 1%-10%, preferred 2%-5%, wetting agent is one or more in glycerol, Polyethylene Glycol, polysorbate, the tween;

3) cleaning agent of 0.5%-10%, preferred 1%-7%, cleaning agent is a dodecyl sodium sulfate;

4) stabilizing agent of 0.05%-2%, preferred 0.1%-1%, stabilizing agent is used to protect the chemistry and the form stable of composition system, is in tetrasodium pyrophosphate, sodium dihydrogen phosphate, EDTA, EDTA disodium, EDTA calcium disodium, the HEDP one or more;

5) abrasive of 5%-60%, preferred 20%-45% is used for the sanding and polishing tooth, and abrasive is the silicon dioxide and/or the calcium carbonate of 5-15 micron grain size;

6) binding agent of 2%-30%, preferred 2%-15%, binding agent is one or more in polyvinylpyrrolidone, methylcellulose, the carboxymethyl cellulose;

7) xylitol of 0.2%-20%, preferred 5%-12% adds xylitol and makes compositions have the caries prevention function concurrently;

8) flavour enhancer of 0.02%-2%, preferred 0.1%-1% is used to regulate the compositions mouthfeel, and flavour enhancer is one or more in Mentholum, peppermint essence, fruity essence, saccharin sodium, aspartame, sucralose, the stevioside;

9) surplus is a deionized water.

The concrete method for preparing of chemical compound according to the invention:

1. desired level is divided into water component 1 and water component 2;

2. in water component 1, add whitening composition, wetting agent, cleaning agent, stabilizing agent, xylitol, flavour enhancer dissolving successively, add the binding agent dissolving then;

3. in water component 2, adding abrasive is uniformly dispersed;

4. two components of step 2 and 3 preparations are combined and stir and became mastic in 30 minutes.

Compared with prior art, the whitening toothpaste composite described in the present invention has better stability.After depositing four months, sample activity of the present invention can reach more than 95%, and volume does not have significant change; After depositing six months, activity can reach more than 91%, and volume does not have significance to be changed.

The specific embodiment

Following non-limiting example is further narrated the preferred embodiment in the scope of the invention.Under the situation that does not deviate from the scope of the invention, a lot of variations of present embodiment are possible.

Embodiment 1

Weight percentages of components

Percarbamide 10.00%

Polyethylene Glycol 2.00%

Dodecyl sodium sulfate 4.00%

Tetrasodium pyrophosphate 0.15%

Sodium dihydrogen phosphate 0.20%

Silicon dioxide 5.60%

Calcium carbonate 22.00%

Polyvinylpyrrolidone 6.50%

Xylitol 5.00%

Saccharin sodium 0.10%

Honey peach essence 0.15%

Deionized water 44.30%

Concrete method for preparing:

1. desired level is divided into water component 1 and water component 2.

2. in water component 1, add Polyethylene Glycol, tetrasodium pyrophosphate, sodium dihydrogen phosphate, xylitol, saccharin sodium, honey peach essence, percarbamide and dodecyl sodium sulfate dissolving successively, add the polyvinylpyrrolidone dissolving then.

3. in water component 2, add calcium carbonate successively, silicon dioxide is uniformly dispersed.

4. two components with above preparation combine and stir 30 minutes one-tenth mastic.

Embodiment 2

Weight percentages of components

Hydrogen peroxide 15.00%

Glycerol 4.00%

Dodecyl sodium sulfate 6.00%

Tetrasodium pyrophosphate 0.10%

DTA disodium 0.25%

Silicon dioxide 8.60%

Calcium carbonate 16.00%

Carboxymethyl cellulose 4.50%

Xylitol 5.00%

Stevioside 0.15%

Honey peach essence 0.15%

Deionized water 40.25%

Concrete method for preparing:

1. desired level is divided into water component 1 and water component 2.

2. in water component 1, add hydrogen peroxide, glycerol, dodecyl sodium sulfate, tetrasodium pyrophosphate, DTA disodium, xylitol, stevioside, the dissolving of honey peach essence successively, add the carboxymethyl cellulose dissolving then.

4. two components of above preparation are combined and stir and made into mastic in 30 minutes.

Embodiment 3

Weight percentages of components

SODIUM PERCARBONATE 18.00%

Tween 5.00%

Dodecyl sodium sulfate 3.00%

Sodium dihydrogen phosphate 0.40%

Silicon dioxide 8.00%

Calcium carbonate 15.00%

Methylcellulose 8.50%

Xylitol 7.00%

Aspartame 0.10%

Honey peach essence 0.15%

Deionized water 34.25%

Concrete method for preparing:

1. desired level is divided into water component 1 and water component 2.

2. in water component 1, add SODIUM PERCARBONATE, tween, dodecyl sodium sulfate, sodium dihydrogen phosphate, xylitol, aspartame, the dissolving of honey peach essence successively, add the methylcellulose dissolving then.

Be the stability of the test present composition, three kinds of samples and the commercially available toothpaste sample that contains peroxide got among the embodiment compare.Observe peroxide activity and the change in volume of sample of each sample after depositing 2 months, after 4 months, after 6 months.Test result shows, compares with the commercially available peroxide toothpaste that contains, and dentifrice composition of the present invention has better stability.

	After 2 months	After 4 months	After 6 months
				Embodiment 1	99%, volume does not have significant change	96%, volume does not have significant change	93%, volume does not have significant change
Embodiment 2	98%, volume does not have significant change	95%, volume does not have significant change	93%, volume does not have significant change
				Embodiment 3	97%, volume does not have significant change	95%, volume does not have significant change	91%, volume does not have significant change
Commercial toothpastes	51%, volumetric expansion	23%, spalling	-

Claims

1. a whitening toothpaste composite that is used for the oral cavity is characterized in that, said concrete component and percentage by weight are following:

1) 1%-20% whitening composition, whitening composition are one or more in hydrogen peroxide, percarbamide, the SODIUM PERCARBONATE;

2) wetting agent of 1%-10%, wetting agent are one or more in glycerol, Polyethylene Glycol, polysorbate, the tween;

3) cleaning agent of 0.5%-10%, cleaning agent are dodecyl sodium sulfate;

4) stabilizing agent of 0.05%-2%, stabilizing agent are used to protect the chemistry and the form stable of composition system, and said stabilizing agent is selected from one or more in EDTA, EDTA disodium, EDTA calcium disodium, the HEDP;

5) abrasive of 5%-60% is used for the sanding and polishing tooth, and abrasive is the silicon dioxide and/or the calcium carbonate of 5-15 micron grain size;

6) binding agent of 2%-30%, binding agent are one or more in polyvinylpyrrolidone, methylcellulose, the carboxymethyl cellulose;

7) xylitol of 0.2%-20% adds xylitol and makes compositions have the caries prevention function concurrently;

8) flavour enhancer of 0.02%-2% is used to regulate the compositions mouthfeel, and flavour enhancer is one or more in Mentholum, peppermint essence, fruity essence, saccharin sodium, aspartame, sucralose, the stevioside;

9) surplus is a deionized water.

2. prepare the described method for compositions of claim 1, it is characterized in that its concrete steps are:

(1) desired level is divided into water component 1 and water component 2;

(2) in water component 1, add whitening composition, wetting agent, cleaning agent, stabilizing agent, xylitol, flavour enhancer dissolving successively, add the binding agent dissolving then;

(3) in water component 2, adding abrasive is uniformly dispersed;

(4) two components of step (2) and (3) preparation are combined and stir became mastic in 30 minutes.