CN101822872A - Eye near-infrared light therapeutic apparatus - Google Patents
Eye near-infrared light therapeutic apparatus Download PDFInfo
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- CN101822872A CN101822872A CN201010155354A CN201010155354A CN101822872A CN 101822872 A CN101822872 A CN 101822872A CN 201010155354 A CN201010155354 A CN 201010155354A CN 201010155354 A CN201010155354 A CN 201010155354A CN 101822872 A CN101822872 A CN 101822872A
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Abstract
The invention discloses an eye near-infrared light therapeutic apparatus, which relates to the eye near-infrared light therapeutic apparatus. The therapeutic apparatus comprises a power supply, an eye mask, a plurality of near-infrared light sources and a plurality of switches. The eye mask can be fixed on the head of the people and cover the eyes, the near-infrared light sources are arranged on the eye mask and are powered up by the power supply, the switches respectively control the on or off of the corresponding near-infrared light sources, the irradiation position of the near-infrared light sources is corresponding to the traditional Chinese medicine acupuncture point of the eyes, and the wave bands of the near-infrared light sources include at least one of 670nm and 830nm. With the application of the near-infrared light, the invention can safely, conveniently and effectively treat the chronic mitochondria traumatic lesions (such as the age-related macular degeneration, the pigment degeneration and the like), the injury diseases (such as the central serous chorioretinopathy, the commotio retinae caused by the trauma and the like) and the neurological diseases (such as the blepharospasm).
Description
Technical field
The present invention relates to a kind of eye near-infrared light therapeutic apparatus, especially treat chronic oculopathy, belong to a therapy of combining Chinese and Western medicine technical field.
Background technology
Discover that near infrared light (630-1000nm, Near infrared Light (NIL)) has facilitation [1] to the healing of tissue.After this, Whelan and other scholars have done a series of zoopery and clinical observation, find that near infrared light can alleviate bone marrow transplantation child's stomatocace and pain [2]; Can promote the healing [3] of diabetic mice wound; Reduce the TCDD inductive chicken embryo death rate of toxicity [4,5]; Promote the rehabilitation of Patients with Brain Tumors and suppress the recurrence [6] of cerebroma; Promote the recovery [7] of ischemic cardiomyopathy; And confirming has certain curative effect [8,9] to the functional rehabilitation of acute methanol poisoning retina and optic nerve injury.Whelan[10] think that near infrared ray is by promoting mitochondrial function, raising cell aerobic metabolism, thereby the survival ability of raising cell under anoxia and poisonous environment, suppressor gene variation and sudden change.Specifically, the raising of mitochondrial function is by promoting the expression of gene that the antioxidative protective substance generates in relevant mitochondrion energy and the cell to raise, triggering signaling mechanism in the cell by mitochondrial cytochrome C oxidase.The result shows that near infrared light can improve the cell aerobic metabolism by promoting mitochondrial function, thereby improves the survival ability of cell under anoxia and poisonous environment, suppressor gene variation and sudden change.He infers near infrared light pair and mitochondrial function decay diseases associated, as retinitis pigmentosa, senile degeneration of macula etc., similar curative effect may be arranged all.Barron has confirmed the increase along with the age, and there is the dysfunction of mitochondrial DNA and cytochrome oxidase really in macular area, because the variation of macular area is more serious than periphery, he infers that this may be relevant with photic damage.The animal model of photic damage is used to simulate senile degeneration of macula always and carries out the basic research in early stage, when having report to support photic damage, the accumulation of oxide has damaged the rod cell mitochondrial DNA, the compensatory death that finally causes rod cell of the mistake of mitochondrial function.
List of references
[1]Whelan?HT，Smits?RL?Jr，Buchman?EV，et?al.Effect?of?NASAlight-emitting?diode?irradiation?on?wound?healing.J?Clin?Laser?Med?Surg，2001，19：305-314.
[2]
Whelan?HT，
Connelly?JF，
Hodgson?BD，et?al.NASA?light-emittingdiodes?for?the?prevention?of?oral?mucositis?in?pediatric?bone?marrowtransplant?patients.
J?Clin?Laser?Med?Surg，2002，20：319-324.
[3]Whelan?HT，Buchmann?EV，Dhokalia?A，et?al.Effect?of?NASAlight-emitting?diode?irradiation?on?molecular?changes?for?wound?healingin?diabetic?mice.J?Clin?Laser?Med?Surg，2003，21：67-74.
[4]Yeager?RL，Lim?J，Millsap?DS，et?al.670nanometer?light?treatmentattenuates?dioxin?toxicity?in?the?developing?chick?embryo.J?Biochem?MolToxicol，2006，20：271-278.
[5]Yeager?RL，Franzosa?JA，Millsap?DS，et?al.Effects?of?670-nmphototherapy?on?development.Photomed?Laser?Surg，2005，23：268-272.
[6]
Schmidt?MH，
Reichert?KW?2nd，
Ozker?K，et?al.Preclinicalevaluation?of?benzoporphyrin?derivative?combined?with?a?light-emittingdiode?array?for?photodynamic?therapy?of?brain?tumors.
Pediatr?Neurosurg，1999，30：225-231.
[7]
Sommer?AP，
Oron?U，
Pretorius?AM，et?al.A?preliminaryinvestigation?into?light-modulated?replication?of?nanobacteria?and?heartdisease.
J?Clin?Laser?Med?Surg，2003，21：231-235.
[8]Eells?JT，Wong-Riley?MT，VerHoeve?J，et?al.Mitochondrial?signaltransduction?in?accelerated?wound?and?retinal?healing?by?near-infraredlight?therapy.Mitochondrion，2004，4：559-567.
[9]
Eells?JT，
Henry?MM，
Summerfelt?P，et?al.Therapeuticphotobiomodulation?for?methanol-induced?retinal?toxicity.
Proc?Natl?Acad Sci?U?S?A，2003，100：3439-3444.
[10]Desmet?KD，Paz?DA，Corry?JJ，et?al.Clinical?and?experimentalapplications?of?NIR-LED?photobiomodulation.Photomed?Laser?Surg，2006，24：121-128.
Summary of the invention
Problem at above-mentioned prior art existence, the object of the invention is to provide a kind of eye near-infrared light therapeutic apparatus, can adopt the near infrared light of safety to carry out treating conveniently, effectively eye centrality slurry retina choroidopathy, senile degeneration of macula etc. and other chronic disease diseases.
Technical scheme of the present invention is: a kind of eye near-infrared light therapeutic apparatus, comprise power supply, can be fixed in human body head and cover the eyeshield of eye, be located on the eyeshield and by some near-infrared light sources of power supply power supply, and some switches of corresponding respectively each near-infrared light source break-make of control, the corresponding eye traditional Chinese medical science of described near-infrared light source irradiation position acupuncture point, the wave band of described near-infrared light source comprises one of 670nm and 830nm at least.
As preferably, the energy range of described near-infrared light source is at 50-80mW/3-5mm
2
As preferably, described near-infrared light source is point-like, and its diameter is at 3-5mm.
As preferably, described near-infrared light source is led light source or CO
2LASER Light Source.
As preferably, traditional Chinese medical science acupuncture point comprises the space between the eyebrows described in above-mentioned each scheme, and yang white is praised bamboo, Yuyao, and te 23, temple, the gb 1 shackles, behind the ball, chengqi, Sibai, one or more in Jingming and the Shangming acupoint.
As preferably, described near-infrared light source is 20, and right and left eyes is respectively 10, corresponding traditional Chinese medical science acupuncture point praise bamboo, Yuyao, te 23, temple, the gb 1 shackles, behind the ball, chengqi, Sibai, Jingming and Shangming acupoint.
Wherein:
1. the disease that cures mainly of Yintang acupoint (being positioned at face, the midpoint of two brows lines) is: strengthening brain and inducing resuscitation, tranquilizing the mind makes eye bright and has one's ideas straightened out.Be applicable to diseases such as preceding headache, dizzy, ophthalmic, flu, spirit are tired, insomnia, rhinitis, hypertension.By being pressed with the bloated sense of acid.
2. the disease that cures mainly of yang white cave (in the volume front portion, at eye level, directly to pupil, 1 cun place on the eyebrow) is: eyelid is beated incessantly, the blepharoptosis person, and eyebrow is sparse, the person of coming off.
3. the disease that cures mainly of Cuanzhu Point (being positioned at face, eyebrow inside edge recess) is: epiphora induced by wind (be commonly called as leak out eye), one's eyes became bloodshot, eyestrain, eye common disease such as acute conjunctivitis, pseudomyopia etc.
Yuyao (winding like fish because of eyebrow, the center of human body is a waist, thus the cave of the centre of eyebrow, the Yuyao of gaining the name) the disease that cures mainly be: blepharoptosis, eye muscle and facial nerve paralysis.
5. te 23 (traditional instrument, promptly thin bamboo; Sky, the space.Brows shape such as thin bamboo, the cave falls into the place, crack the tip of the brow) the disease that cures mainly be: migraine, facial paralysis and otopathy.
6. temple (intersect the recess of two line intersection points with tip of the brow extended line and orbit extended line.During finger pressure, can clench one's teeth earlier, can find out like this and be positioned at the muscle arteries and veins that floats in the temple place, be temporal position herein) the disease that cures mainly be: eliminate near the eyes and facial wrinkles, the prevention cataract is alleviated dizziness, headache, visual deterioration, treatment laryngalgia, toothache, facial paralysis etc.
7. gb 1 shackles (cave name gb 1, pupil; Shackles, the bone crack.Quadrate bone crack place outside the ommatidium angle, cave, horizontal to pupil) cure mainly disease: headache, supraorbital bone pain, conjunctival congestion with ophthalmalgia, ametropia, corneal leukoma, keratitis, optic atrophy symptom.
8. (outside of chengqi, the oblique below of the white of the eye) cures mainly disease behind the ball: ocular disease
9. Tongzi point (is positioned at face, the straight below of pupil is between eyeball and the inferior orbit edge) cure mainly disease: common multiple ocular disease such as myopia, nyctalopia, ophtalmodonesis, blepharospasm, keratitis, optic atrophy, eyestrain, epiphora induced by wind, presbyopia, cataract.
10. the main disease to be treated of SIBAI point (be positioned at face, when eyes are looked squarely, about 2 centimeters under the pupil centre) is: this acupoint of finger pressure, can improve the eyes function, and very effective in cure for ocular disease such as myopia, achromatopsia.
11. the disease that cures mainly of Jingming acupoint (be positioned at the eye inboard, inner eye corner is the top recess slightly) is: epiphora induced by wind, migraine, conjunctivitis, blepharitis, eyestrain, ocular disease, trigeminal neuralgia, myopia etc.
12. Shangming acupoint (in the geisoma mid point, below the eye socket upper limb) cures mainly: ametropia.
The invention has the beneficial effects as follows: the near infrared light radiostimulation is through testing preferred human acupoint, and both combinations have strengthened radiating therapeutic effect greatly, and the systematicness of human body venation also makes it reach whole coordination treatment simultaneously, further improves effect.Except centrality slurry retina choroidopathy, it all has certain curative effect to senile degeneration of macula and other chronic diseases: chronic mitochondrial injury sexually transmitted disease (STD) becomes (as senile degeneration of macula and pigmental degeneration etc.) and injury disease (commotio retinae that causes as centrality slurry retina choroidopathy and wound etc.), and nervous system disease (as blepharospasm).The near-infrared luminous energy of 830nm shortens the course of disease of centrality slurry retina choroidopathy, promotes the absorption of hydrops under the nethike embrane.The applicant's clinical observation 60 routine patients, find that 830nm irradiation eye can improve cure rate, shortens the course of disease (seeing Table 1).The course of disease of matched group is in 13 weeks, and the 830nm group had only about 4 weeks, and the cure rate of treatment group simultaneously is 96%, and matched group has only 41%.
Two groups of clinical healing courses of disease compare: see Table 1
The table 1 liang group clinical healing course of disease relatively
As seen from the above table, 1. there is significant difference treatment back P＜0.05, illustrates that the two groups of curative effects in treatment back are variant.2. in the group relatively, * represent with treatment before compare P＜0.05, significant difference is arranged, illustrate that same group compares, variant before and after the treatment.
Table 2 a liang group vision changes relatively
As seen from the above table, 1. treatment back P＜0.05 does not have and adds up variant, and the two groups of curative effects in treatment back are described, and there were significant differences.2. in the group relatively, * represent with treatment before compare P＜0.05, significant difference is arranged, illustrate that same group compares, variant before the treatment with the treatment back.
Table 3 liang group treatment back total effective rate relatively
P＜0.05, show treatment after, treatment group and matched group total effective rate difference have statistical significance.
1 routine patient is arranged because to fluorescein sodium allergy, can not radiography, so determine breakthrough,, do not heal at present in treatment group treatment March always.
Therapeutic instrument of the present invention also has therapeutical effect to diseases such as senile degeneration of macula, and this part does not have clinical observation result, but the result of infrastest is arranged.Closely related in view of senile degeneration of macula and photic damage, the applicant has done zoopery, has confirmed the protective effect of 670nm near infrared light to SD (Sprague dawley) retinal photic injury in rats model.670nm laser can clearly alleviate the photic damage of rat.
In addition, the treatment because the patient is in can't be aimed at breakthrough with hot spot, the acupoint therapy method of the traditional Chinese medical science of the present invention, because the acupuncture point distinguishes easily that in the position of eye the patient's symptomatic treatment of being more convenient for can make things convenient for the patient, and liberation doctor's work.
Description of drawings
Fig. 1 is a traditional Chinese medical science human body eye acupuncture point distribution schematic diagram;
Fig. 2 is a near-infrared light source distribution schematic diagram of the present invention.
The specific embodiment
As one embodiment of the present invention, as depicted in figs. 1 and 2, a kind of eye near-infrared light therapeutic apparatus comprises power supply, can be fixed in human body head and cover the eyeshield of eye, be located on the eyeshield and by some near-infrared light sources of power supply power supply, and some switches of corresponding respectively each near-infrared light source break-make of control, the corresponding eye traditional Chinese medical science of described near-infrared light source irradiation position acupuncture point, described traditional Chinese medical science acupuncture point comprises the space between the eyebrows, yang white, praise bamboo, Yuyao, te 23, temple, the gb 1 shackles, behind the ball, chengqi, Sibai, one or more in Jingming and the Shangming acupoint, the wave band of described near-infrared light source comprises one of 670nm and 830nm at least.As preferably, as shown in this embodiment, the energy range of described near-infrared light source is at 50-80mW/3-5mm
2, described near-infrared light source is point-like, and its diameter is at 3-5mm, and described near-infrared light source is led light source or CO
2LASER Light Sources etc., described near-infrared light source are 20, and right and left eyes is respectively 10, corresponding traditional Chinese medical science acupuncture point praise bamboo, Yuyao, te 23, temple, the gb 1 shackles, behind the ball, chengqi, Sibai, Jingming and Shangming acupoint.Described eyeshield can have 2 types, the 670nm therapeutic instrument of single light source and the 670nm of two light sources and the therapeutic instrument of 830nm.She Ji reason is like this, and 670nm is visible-near infrared, and the patient gets used to seeing the improvement instrument luminous, and clear and definite its worked, so the single light source design just can be finished the work.And the therapeutic instrument of 830nm is invisible near infrared light, and the patient cannot see light source in working order, can have query during treatment, with the placed in-line 670nm light source of 830nm light source, has served as the indication light source like this, but therapeutical effect, better efficacy are also arranged simultaneously.
The 670nm therapeutic instrument of single light source, its 20 LED bulbs are to be connected in parallel on the power line, the other tandem tap of bulb; Adopt press-button type switch, each light source just often is the state of upspringing, and opens, if the patient does not need certain acupuncture point, just it is pressed, and it is in closed condition.
Light source is respectively the therapeutic instrument of 670nm and 830nm, and its LED bulb also is to be connected in parallel on the power line; The bulb of a 670nm but the light source of each 830nm is connected simultaneously, the other tandem tap again of bulb.
Using method: each near-infrared light source can also can shine by eyes in simple eye irradiation.If certain acupuncture point does not need, also it can be closed or blocks, its effect is pressed at the acupuncture point, can elective irradiation.The used energy of point source does not produce the dosage under the dosage threshold value of pathology damage, 50-80mwW/3-5mm for our eye laser irradiation
2, amphiblestroid photoreceptor cell is the most responsive to light, and the dosage that can not damage amphiblestroid photoreceptor cell can damage the cell at acupuncture point scarcely, and therefore the dosage of design is safe.All treatment time is approximately 10min at every turn, and this is by our safe dose that zoopery and clinical observation confirmed.In fact, our zoopery confirms that the irradiation of 30min all is safe.But for the purpose of being perfectly safe, all treatment time is no more than 15min at every turn in control.
The treatment example: become example with centrality slurry retina choroidopathy, make fluoroscopic visualization before the irradiation, OCT vision and perimetry are clarified a diagnosis.Choose the Tongzi point of suffering from eye, the gb 1 shackles, behind the ball, SIBAI point, Shangming acupoint and Cuanzhu Point etc.Shine once every day, 10min, 50mw/3mm
2, choose 830nm wave band near infrared light.Be 10-14 days the course of treatment.After the treatment, checking eyesight, OCT, confirm that liquid absorbs under the nethike embrane after, the check fluoroscopic visualization and the visual field, and follow up a case by regular visits to visual function and recover fully.
More than a kind of eye near-infrared light therapeutic apparatus provided by the present invention has been carried out detailed introduction, used specific case herein principle of the present invention and embodiment are set forth, the explanation of above embodiment just is used for helping to understand method of the present invention and core concept thereof; Simultaneously, for one of ordinary skill in the art, according to thought of the present invention, the part that all can change in specific embodiments and applications, in sum, this description should not be construed as limitation of the present invention.
Claims (6)
1. eye near-infrared light therapeutic apparatus, it is characterized in that: comprise power supply, can be fixed in human body head and cover the eyeshield of eye, be located on the eyeshield and by some near-infrared light sources of power supply power supply, and some switches of corresponding respectively each near-infrared light source break-make of control, the corresponding eye traditional Chinese medical science of described near-infrared light source irradiation position acupuncture point, the wave band of described near-infrared light source comprises one of 670nm and 830nm at least.
2. a kind of eye near-infrared light therapeutic apparatus according to claim 1 is characterized in that: the energy range of described near-infrared light source is at 50-80mW/3-5mm
2
3. a kind of eye near-infrared light therapeutic apparatus according to claim 1 is characterized in that: described near-infrared light source is point-like, and its diameter is at 3-5mm.
4. a kind of eye near-infrared light therapeutic apparatus according to claim 1 is characterized in that: described near-infrared light source is led light source or CO
2LASER Light Source.
5. according to a kind of eye near-infrared light therapeutic apparatus described in arbitrary claim in the claim 1 to 4, it is characterized in that: described traditional Chinese medical science acupuncture point comprises the space between the eyebrows, and yang white is praised bamboo, Yuyao, te 23, temple, gb 1 shackles, behind the ball, chengqi, Sibai, one or more in Jingming and the Shangming acupoint.
6. a kind of eye near-infrared light therapeutic apparatus according to claim 5 is characterized in that: described near-infrared light source is 20, and right and left eyes is respectively 10, corresponding traditional Chinese medical science acupuncture point praise bamboo, Yuyao, te 23, temple, gb 1 shackles, behind the ball, chengqi, Sibai, Jingming and Shangming acupoint.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012011839A1 (en) * | 2010-07-23 | 2012-01-26 | Zhyestkov Syergyej Alyeksandrovich | Apparatus for the prophylaxis and correction of the functional systems of a human organism |
| RU2495620C1 (en) * | 2012-06-27 | 2013-10-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт глазных болезней" Российской академии медицинских наук (ФГБУ "НИИГБ" РАМН) | Method of determining indications for photodynamic therapy of chronic central serous chorioretinopathy |
| CN103462787A (en) * | 2012-06-08 | 2013-12-25 | 河北路德医疗器械有限公司 | Vision training instrument |
| CN104939970A (en) * | 2015-06-11 | 2015-09-30 | 宋兹洋 | Infrared eye treatment device |
| CN108324551A (en) * | 2018-03-21 | 2018-07-27 | 贝贝明实业（武汉）有限公司 | A kind of myopia rehabilitation instrument |
| CN111603685A (en) * | 2020-06-15 | 2020-09-01 | 电子科技大学 | Near infrared light eyeground therapeutic instrument |
| WO2020244675A1 (en) | 2019-06-06 | 2020-12-10 | 中山大学中山眼科中心 | Method for increasing blood flow and metabolic rate of eye fundus |
| CN112657067A (en) * | 2021-01-12 | 2021-04-16 | 昆明医科大学第一附属医院 | Photo-biological regulation therapeutic apparatus for preventing and treating high myopia retinopathy and use method thereof |
| CN112675435A (en) * | 2021-01-12 | 2021-04-20 | 昆明医科大学第一附属医院 | Photobiological regulation therapeutic apparatus for treating age-related macular degeneration and using method |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012011839A1 (en) * | 2010-07-23 | 2012-01-26 | Zhyestkov Syergyej Alyeksandrovich | Apparatus for the prophylaxis and correction of the functional systems of a human organism |
| CN103462787A (en) * | 2012-06-08 | 2013-12-25 | 河北路德医疗器械有限公司 | Vision training instrument |
| RU2495620C1 (en) * | 2012-06-27 | 2013-10-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт глазных болезней" Российской академии медицинских наук (ФГБУ "НИИГБ" РАМН) | Method of determining indications for photodynamic therapy of chronic central serous chorioretinopathy |
| CN104939970A (en) * | 2015-06-11 | 2015-09-30 | 宋兹洋 | Infrared eye treatment device |
| CN108324551A (en) * | 2018-03-21 | 2018-07-27 | 贝贝明实业（武汉）有限公司 | A kind of myopia rehabilitation instrument |
| WO2020244675A1 (en) | 2019-06-06 | 2020-12-10 | 中山大学中山眼科中心 | Method for increasing blood flow and metabolic rate of eye fundus |
| CN111603685A (en) * | 2020-06-15 | 2020-09-01 | 电子科技大学 | Near infrared light eyeground therapeutic instrument |
| CN112657067A (en) * | 2021-01-12 | 2021-04-16 | 昆明医科大学第一附属医院 | Photo-biological regulation therapeutic apparatus for preventing and treating high myopia retinopathy and use method thereof |
| CN112675435A (en) * | 2021-01-12 | 2021-04-20 | 昆明医科大学第一附属医院 | Photobiological regulation therapeutic apparatus for treating age-related macular degeneration and using method |
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Application publication date: 20100908 |