CN101810323A - Health-care food capable of strengthening immunity and radiation resisting function - Google Patents
Health-care food capable of strengthening immunity and radiation resisting function Download PDFInfo
- Publication number
- CN101810323A CN101810323A CN200910067904A CN200910067904A CN101810323A CN 101810323 A CN101810323 A CN 101810323A CN 200910067904 A CN200910067904 A CN 200910067904A CN 200910067904 A CN200910067904 A CN 200910067904A CN 101810323 A CN101810323 A CN 101810323A
- Authority
- CN
- China
- Prior art keywords
- health food
- radiation
- parts
- extract
- resisting functional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides health-care food capable of strengthening immunity and a radiation resisting function. The health-care food is prepared from the following raw materials in part by weight: 10 to 100 parts of ginseng polysaccharide, 10 to 100 parts of siberian ginseng extract, 30 to 300 parts of kelp, 1 to 50 parts of royal jelly, 0.1 to 30 parts of hemin, 5 to 50 parts of Vc and 0.01 to 1 part of folic acid. The health-care food is suitable for sub-healthy people having a main symptom of low immunologic function, weak elders, people suffering prolonged illnesses, operators accessing to radiation, cancer patients receiving chemical therapy and radioactive therapy and patients suffering from toxic and side effects of low immunologic function, decreasing number of white cells and blood erythrocytes and the like caused by the chemical therapy and the radioactive therapy.
Description
Technical field:
The invention belongs to a kind of health food, particularly a kind of health food with enhancing immunity and radiation-resisting functional.
The crowd that it is suitable for comprises immunologic hypofunction or be the sub-health population of main disease with immunologic hypofunction, and is worn with age, prolonged illness valetudinarian, invalid, and the staff of contact radiation and the cancer patient who carries out or carried out chemotherapy, radiotherapy.Also can be used as because of hemogram abnormities such as leucocyte that chemotherapy, radiotherapy cause, erythrocyte reduction change, anorexia, dispirited, the auxiliary health food of degradation toxic and side effect under the immunologic function.China a middle-aged person, especially the colony of the sub-health state among the white collar is very general, add that China has stepped into aging society, worn with age, prolonged illness valetudinarian, invalid is a lot of, and cancer morbidity is global ascendant trend, and chemotherapy, radiotherapy now remains the main means of treatment of cancer, but its toxic and side effect is very big again, knows perfectly well poisonously, but must use.Therefore range of application of the present invention is extremely extensive.
The object of the present invention is to provide a kind of enhancing immunity, radiation-resistant health food, to improve sub-health population and old patients on long-term's immunologic function, strengthen its physique, and alleviate, improve the quality of life of cancer patient with knurl existence because of the toxic and side effect of changing, radiotherapy produces.
Technical scheme of the present invention is: a kind of health food with enhancing immunity, radiation-resisting functional is characterized in that: made according to following weight proportion by following raw materials according.
10～100 parts of panaxans
10～100 parts of siberian Ginseng P.Es
30～300 parts of kelps
1～50 part of royal jelly
0.1～30 part of hemin
5～50 parts of Vc
0.1～1 part in folic acid
Above-mentioned raw materials can be made various formulations such as hard shell capsules, soft capsule, tablet, granule, supensoid agent, pill, syrup, emulsion.
Preparation method of the present invention: the panaxan adopts genseng, gen-seng haulms, panax ginseng fruit to extract in the residue behind the ginsenoside to extract, its method is to extract 3～5 times with 5～20 times of water, the each extraction 2～6 hours merges extract, and being evaporated to relative density is 1.02～1.10, add 95% ethanol alcohol precipitation, make to contain the alcohol amount 60～80%, solids is got in filtration or centrifugal, 65～75 ℃ of vacuum drying get Powdered panaxan to doing.The kelp medicinal material should meet the Chinese Pharmacopoeia regulation, is ground into meal, extract 2～6 times with 10～30 times of water, and each 2～4 hours merging extracts, being evaporated to relative density is that 1.20～1.40,65～75 ℃ of vacuum drying are extremely done, and gets Thallus Laminariae (Thallus Eckloniae) extract.With siberian Ginseng P.E, royal jelly freeze-dried powder, hemin, Vc, folic acid, the common pulverizing mixes, and adds auxiliary materials and mixing.Auxiliary material comprises silica, microcrystalline cellulose, L-HPC, dolomol, talcum powder, 30 POVIDONE K 30 BP/USP 30, dextrin etc., makes corresponding preparation.
This product acute toxicity test in mice is LD as a result
50＞15g/Kg is non-poisonous material.
Salmonella reversion test shows that this product do not have mutagenesis; The PCEMNR micronucleus test shows that this product does not exert an influence to the PCEMNR micronucleus; Chromosome aberration does not exert an influence mouse testis chromosomal aberration test this product to mouse testis, and genetic toxicity test is all negative.
Rat was fed 30 days, low (1.00g/Kg), in body weight, weightening finish and food utilization and control group comparison, the difference that there are no significant (P＞0.05) of (2.00g/Kg), high (4.00g/Kg) each dosage group; Hematology and blood biochemical are learned and are detected each index all in range of normal value, with the relatively more equal not statistically significant (P＞0.05) of control group.
Inspection and internal organs system are all no abnormal substantially, and each treated animal organ weights and dirty body ratio are compared difference with control group do not have conspicuousness (P＞0.05).Histopathologic examination finds no that typical Histopathology changes and specificity is damaged, and shows that this product do not see tangible toxic action.
This product is a kind of health food that strengthens immunity and radiation-resisting functional that has, and its functional component is the 10-hydroxyl-2-decylenic acid in panaxan, laminarin, Radix Et Caulis Acanthopanacis Senticosi polysaccharide, wilsonii saponin(e and the royal jelly.This product has been formulated the content of thick polysaccharide and the content assaying method of eleutheroside B (Syringin), and formulates the method for 10-hydroxyl-qualitative discriminating of 2-decylenic acid thin-layer chromatography.These methods are accurate, easy, be easy to repetition.Thick content Determination of Polysaccharide adopts AAS, eleutheroside B assay adopts high performance liquid chromatography, the thin-layered chromatography of 10-hydroxyl-2-decylenic acid is finished first, for the quality of control this product has played guaranteeing role, thereby has ensured the stable effect, definite of this health food.
Advantage of the present invention is: be a kind of enhancing immunity and radiation-resistant health food, have no side effect that the crowd that is suitable for is extensive, and instant, and the waste material of the ginsenoside that extracted further developed, with low cost, easy and simple to handle, remarkable benefit.
The specific embodiment:
Embodiment 1---hard shell capsules
Genseng dregs of a decoction 200g
Extractum Acanthopanacis Senticosi powder 70g
Kelp 333.3g
Royal jelly 16.7g
Vc 33.3g
Hemin 1.7g
Folic acid 0.01g
Microcrystalline cellulose is an amount of
Silica is an amount of
Make 1000, the 0.35g/ grain
Kelp boils 2 times with 30,15 times of decoctings respectively, and each 2 hours, collecting decoction filtered, and being evaporated to relative density is 1.20～1.40,65～75 ℃ of vacuum drying, gets dry powder; The genseng dregs of a decoction add 5～20 times of water and extract 3 times, and each 2～6 hours, merge extract, being evaporated to relative density is 1.02～1.10, with 95% ethanol alcohol precipitation, make to contain the alcohol amount 60～80%, filter, get solids, 65～75 ℃ of vacuum drying get panaxan's powder to doing.The common pulverizing of Extractum Acanthopanacis Senticosi powder, royal jelly, Vc, folic acid and microcrystalline cellulose, silica of last two extracts and recipe quantity mixed, cross 60 mesh sieves, incapsulate promptly.
Embodiment 2---tablet
The raw material preparation is with embodiment 1
Auxiliary material changes dextrin, dolomol, talcum powder into.
Make 1000, sheet is heavy: the 0.35g/ sheet, use the chlorophyll film coating.
Embodiment 3---soft capsule
The raw material preparation is with embodiment 1
Auxiliary material changes salad oil, palm oil, beeswax into.The capsule skin is a cologne earth look gelatin
Make 1000, the 0.5g/ grain.
Claims (8)
1. one kind has the health food that strengthens immunity, radiation-resisting functional, it is characterized in that: made according to following weight proportion by following raw materials according.
10～100 parts of panaxans
10～100 parts of siberian Ginseng P.Es
30～300 parts of kelps
1～50 part of royal jelly
0.1～30 part of hemin
5～50 parts of Vc
0.1～1 part in folic acid
2. a kind of health food that strengthens immunity, radiation-resisting functional that has according to claim 1, it is characterized in that: above-mentioned health food can be made various formulations such as hard shell capsules, soft capsule, tablet, granule, supensoid agent, pill, syrup, emulsion.
3. a kind of enhancing immunity that has according to claim 1, the health food of radiation-resisting functional, it is characterized in that: the panaxan adopts genseng in the above-mentioned health food, gen-seng haulms, extract in the residue behind the panax ginseng fruit extraction ginsenoside, its method is to extract 3～5 times, each 5～20 times of water extract, the each extraction 2～6 hours, merge extract, being evaporated to relative density is 1.02～1.10, with 95% ethanol alcohol precipitation, make to contain the alcohol amount 60～80%, solids is got in filtration or centrifugal, 65～75 ℃ of vacuum drying get Powdered panaxan to doing.
4. a kind of health food that strengthens immunity, radiation-resisting functional that has according to claim 1, it is characterized in that: the kelp in the above-mentioned health food is ground into meal, extract 2～6 times, extract with 10～30 times of water at every turn, each 2～4 hours, merge extract, being evaporated to relative density is 1.20～1.40,65～75 ℃ of vacuum drying get Thallus Laminariae (Thallus Eckloniae) extract to doing.
5. a kind of health food that strengthens immunity, radiation-resisting functional that has according to claim 1, it is characterized in that: claim 3,4 income earner's gracilis polysaccharides and Thallus Laminariae (Thallus Eckloniae) extract and described other raw material of claim 1 and auxiliary material are fully mixed, used auxiliary material comprises silica, microcrystalline cellulose, L-HPC, dolomol, talcum powder, 30 POVIDONE K 30 BP/USP-30, dextrin, makes the described various formulations of claim 2.
6. a kind of health food that strengthens immunity, radiation-resisting functional that has according to claim 1 is characterized in that: use the content of total thick polysaccharide in the spectrophotometry finished product, every 100g finished product contains total thick polysaccharide and is not less than 5～50g.
7. a kind of health food that strengthens immunity, radiation-resisting functional that has according to claim 1, it is characterized in that: siberian Ginseng P.E is used the content of high effective liquid chromatography for measuring eleutheroside B (Syringin), and every 100g contains eleutheroside B and is not less than 0.1～10g.
8. a kind of health food that strengthens immunity, radiation-resisting functional that has according to claim 1 is characterized in that: the application of thin layer chromatography serves as that the qualitative discriminating of royal jelly is carried out in contrast with 10-hydroxyl-2-decylenic acid.Its chromatographic condition is: adsorbent is the silica gel H lamellae, the point sample amount is 2～10 μ l, solvent is benzene-ethyl acetate-methyl alcohol (2.5: 2: 0.5), developer is bromocresol green-methyl red reagent, inspect under the natural daylight, in the chromatogram of finished product and royal jelly raw material, with the orange red spot that shows same color on reference substance 10-hydroxyl-corresponding position of 2-decylenic acid chromatogram.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910067904A CN101810323A (en) | 2009-02-23 | 2009-02-23 | Health-care food capable of strengthening immunity and radiation resisting function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910067904A CN101810323A (en) | 2009-02-23 | 2009-02-23 | Health-care food capable of strengthening immunity and radiation resisting function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101810323A true CN101810323A (en) | 2010-08-25 |
Family
ID=42617814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200910067904A Pending CN101810323A (en) | 2009-02-23 | 2009-02-23 | Health-care food capable of strengthening immunity and radiation resisting function |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101810323A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103202916A (en) * | 2013-01-09 | 2013-07-17 | 河北联合大学 | Medicinal and edible health care liquid for resisting mobile phone radiation |
| CN103202466A (en) * | 2013-01-09 | 2013-07-17 | 唐山职业技术学院 | Health care liquid for resisting mobile phone radiation in gestation period |
| WO2018139898A1 (en) * | 2017-01-26 | 2018-08-02 | (주)아모레퍼시픽 | Composition for enhancing immunity, containing ginseng berry polysaccharides |
| CN109984343A (en) * | 2019-04-02 | 2019-07-09 | 湖南德雅医药科技有限公司 | A kind of compound ginseng polyoses grain for improving immunity and mitigating tumor chemoradiotherapy reaction |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19907586A1 (en) * | 1999-02-22 | 2000-08-24 | Bonermo Health Gmbh | Nutritional supplement for ensuring good health, comprises basic kit of constant amounts of vitamins and minerals plus add-on containing varying amounts of additives, allowing adjustment of dosages |
| CN1611232A (en) * | 2003-10-30 | 2005-05-04 | 北京欧纳尔生物工程技术有限公司 | Medicinal composition with main effect of antifatigue, radioresistance and melancholia-resistance and its preparing method |
| CN1631217A (en) * | 2004-11-29 | 2005-06-29 | 沈道金 | Concentrated solution of acanthopanax root, royal jelly, pollen and honey and method for making it |
-
2009
- 2009-02-23 CN CN200910067904A patent/CN101810323A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19907586A1 (en) * | 1999-02-22 | 2000-08-24 | Bonermo Health Gmbh | Nutritional supplement for ensuring good health, comprises basic kit of constant amounts of vitamins and minerals plus add-on containing varying amounts of additives, allowing adjustment of dosages |
| CN1611232A (en) * | 2003-10-30 | 2005-05-04 | 北京欧纳尔生物工程技术有限公司 | Medicinal composition with main effect of antifatigue, radioresistance and melancholia-resistance and its preparing method |
| CN1631217A (en) * | 2004-11-29 | 2005-06-29 | 沈道金 | Concentrated solution of acanthopanax root, royal jelly, pollen and honey and method for making it |
Non-Patent Citations (3)
| Title |
|---|
| 国家药典委员会: "《中华人民共和国药典（一部）》", 30 December 2005, 化学工业出版社 * |
| 王全喜: "昆布用于保健食品的药理研究", 《食品研究与开发》 * |
| 蔡柳: "蜂王浆中10-HDA的研究现状及前景展望", 《农产品加工》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103202916A (en) * | 2013-01-09 | 2013-07-17 | 河北联合大学 | Medicinal and edible health care liquid for resisting mobile phone radiation |
| CN103202466A (en) * | 2013-01-09 | 2013-07-17 | 唐山职业技术学院 | Health care liquid for resisting mobile phone radiation in gestation period |
| WO2018139898A1 (en) * | 2017-01-26 | 2018-08-02 | (주)아모레퍼시픽 | Composition for enhancing immunity, containing ginseng berry polysaccharides |
| US11219653B2 (en) | 2017-01-26 | 2022-01-11 | Amorepacific Corporation | Composition for enhancing immunity, containing ginseng berry polysaccharides |
| CN109984343A (en) * | 2019-04-02 | 2019-07-09 | 湖南德雅医药科技有限公司 | A kind of compound ginseng polyoses grain for improving immunity and mitigating tumor chemoradiotherapy reaction |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1732578B1 (en) | Plant-based medicament for the treatment of hepatitis c | |
| Czigle et al. | Ginkgo biloba food supplements on the European market–adulteration patterns revealed by quality control of selected samples | |
| US20080233220A1 (en) | Further Medical Use Of A Botanical Drug Or Dietary Supplement | |
| Hasan et al. | Phytochemical and pharmacological evaluation of ethanolic extract of Lepisanthes rubiginosa L. leaves | |
| Sharma et al. | Identification, purification and quantification of andrographolide from Andrographis paniculata (burm. F.) Nees by HPTLC at different stages of life cycle of crop | |
| Klymenko et al. | Iridoids, flavonoids, and antioxidant capacity of Cornus mas, C. officinalis, and C. mas× C. officinalis fruits | |
| Ya'u et al. | Safety assessment of the standardized extract of Carissa edulis root bark in rats | |
| Shariatifar et al. | Study on diuretic activity of saffron (stigma of Crocus sativus L.) Aqueous extract in rat | |
| CN105758950B (en) | Qizhi weitong granules anti-inflammatory and antalgic method of quality control based on dose-effect colour atla | |
| Bae et al. | Differences in the chemical profiles and biological activities of Paeonia lactiflora and Paeonia obovata | |
| Hussain et al. | Hepatoprotective evaluation of Trapa natans against drug-induced hepatotoxicity of antitubercular agents in rats | |
| CN101810323A (en) | Health-care food capable of strengthening immunity and radiation resisting function | |
| CN105738519B (en) | A kind of qizhi weitong granules antiulcer method of quality control based on dose-effect colour atla | |
| Bhadoriya et al. | Diuretic activity of extract of Salvia officinalis L | |
| Dong et al. | A review of the botany, ethnopharmacology, phytochemistry, analysis method and quality control, processing methods, pharmacological effects, pharmacokinetics and toxicity of codonopsis radix | |
| Mugomeri et al. | Phytochemical characterization of selected herbal products in Lesotho | |
| Li et al. | Research on correlation of compositions with oestrogenic activity of Cistanche based on LC/Q-TOF-MS/MS technology | |
| Moon et al. | Antihypertensive effects of Korean wild simulated ginseng (Sanyangsam) extracts in spontaneously hypertensive rats | |
| Borquaye et al. | Anti-inflammatory, antioxidant and total phenolic content of the ethanolic extracts of Celtis africana Burm. f | |
| CN103316074B (en) | Medicine composite of halenia corni extract, astragalus extract and liquorice extract as well as preparation and application of medicine composite | |
| Sulaimon et al. | Evaluation of antidiabetic activity of Irvingia gabonensis (Aubry-Lecomte ex O’Rorke) leaf and bark in alloxan induced diabetic rats | |
| CN101123975A (en) | Screening method (metabolite grid) for novel therapeutic extracts and molecules for Diabetes | |
| Maphosa et al. | Toxicity evaluation of the aqueous extract of the rhizome of Elephantorrhiza elephantina (Burch.) Skeels.(Fabaceae), in rats | |
| Gunatilake et al. | Aerva lanata (Polpala): Its effects on the structure and function of the urinary tract | |
| Shen et al. | Hotspot Analysis of Traditional Drugs in Diabetes Treatment Literature |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100825 |