CN101792397A - Method for separating mixture of glycine and iminodiacetic acid by electrodialysis - Google Patents
Method for separating mixture of glycine and iminodiacetic acid by electrodialysis Download PDFInfo
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- CN101792397A CN101792397A CN201010154314A CN201010154314A CN101792397A CN 101792397 A CN101792397 A CN 101792397A CN 201010154314 A CN201010154314 A CN 201010154314A CN 201010154314 A CN201010154314 A CN 201010154314A CN 101792397 A CN101792397 A CN 101792397A
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Abstract
The invention provides a method for separating a mixture of glycine and iminodiacetic acid by the film separating technique, particularly an electrodialysis technique. According to different material content ratio of the mixture of glycine and iminodiacetic acid, a pH value of aqueous solution is adjusted till an isoelectric point of the glycine of 5.97 is reached or till an isoelectric point of the iminodiacetic acid of 1.96 is reached.
Description
Technical field the present invention relates to a kind of glycine and iminodiethanoic acid separating mixture, belongs to technical field of chemical separation.
Technical background is produced in methyl alcohol ammonification (catalysis) dehydrogenation single stage method in the middle of the technology of glycine and iminodiethanoic acid, and the solid product that reaction is finished mainly is the mixture (content of glycine is 1%--99% in the mixture) of glycine and iminodiethanoic acid.Use different catalyzer and reaction conditions conditions such as () the material ratios of temperature, methyl alcohol and liquefied ammonia by control, can obtain the glycine and the iminodiethanoic acid solid miscellany product of different ratios.Sometimes the marquis is also contained other a spot of other solid kind impurity (as amides product etc.) except glycine and two kinds of products of iminodiethanoic acid.In the engineering of filtering glycine and iminodiethanoic acid solid product, other product of dissolved in the methanol liquid (iminodiacetonitrile, hydroxyacetonitrile, urotropine, aminoacetonitriles, other amine etc.) has a small amount of mixing in the middle of solid glycine and the iminodiethanoic acid.Therefore need a kind of separation method, obtain highly purified glycine product and highly purified iminodiacetic acid (salt) acid product.
Summary of the invention the invention provides a kind of method of utilizing membrane separation technique separation of glycine and iminodiacetic acid (salt) acid mixture, and concrete scheme is to utilize the method for electrodialytic technique separation of glycine and iminodiacetic acid (salt) acid mixture.The present invention is by following concrete scheme implementation:
At first the mixture (content of glycine is 1%--99% in the mixture) with glycine and iminodiethanoic acid is dissolved in the water, and it is the aqueous solution of 3%-25% that proportioning becomes solid content, the concentration ratio of preferred 5%-10% solid content.
Different according to material content ratio in glycine and the iminodiacetic acid (salt) acid mixture, the pH value of regulating the aqueous solution is to the iso-electric point 5.97 of glycine or be adjusted to the iso-electric point 1.96 of iminodiethanoic acid.Fundamental principle is the iso-electric point that glycine content higher position is adjusted to solution glycine; Iminodiacetic acid (salt) acid content higher position is adjusted to the iso-electric point of iminodiethanoic acid.When utilizing electrodialysis to separate, use the pH value of the automatic regulator solution of the on-line automatic controller of PH.Regulate iso-electric point and use hydrochloric acid and sodium hydroxide solution.The iso-electric point of glycine is controlled between the 5.80-6.14 when utilizing electrodialysis to separate; The iso-electric point of iminodiethanoic acid is controlled between the 1.82-2.13.The film that electrodialysis is used can be a homogeneous ion-exchange membrane, also can select heterogeneous ion-exchange membrane for use.
After utilizing electrodialysis appts to finish the solution of separation of glycine and iminodiethanoic acid, liquid to electrodialysis appts freshwater room and dense hydroecium the inside carries out concentrating under reduced pressure respectively, be concentrated to the crystallization of finite concentration postcooling, behind the filtration drying, obtain glycine and iminodiacetic acid (salt) acid product respectively.Also can utilize the high pressure reverse osmosis equipment to concentrate to the liquid inside freshwater room or the dense hydroecium earlier, again concentrated solution be carried out concentrating under reduced pressure, be concentrated to the crystallization of finite concentration postcooling, behind the filtration drying, obtain glycine and iminodiacetic acid (salt) acid product respectively.
Example:
Adopting baffle dimensions is 160mm * 400mm electrodialysis unit, selects homogeneous membrane for use, and the loop dividing plate is arranged, and circulation method is adopted in experiment.Select glycine content 80%, the mixture of iminodiacetic acid (salt) acid content 18%, dissolving is made into the solution of solid content 5%.The pH value of regulator solution is opened the pH value of the automatic regulator solution of the on-line automatic controller of PH to the iso-electric point 5.97 of glycine, and regulation range uses hydrochloric acid and sodium hydroxide solution to regulate between 5.80-6.14.The feed liquid flow is 300L/h, when running voltage is 30V, when the freshwater room solid content stops to separate 4% the time.Dense hydroecium liquid and freshwater room liquid are used the high pressure reverse osmosis concentration respectively, are concentrated into material content about 15%, underpressure distillation again, and crystallisation by cooling obtains the glycine product of content more than 99.9% in freshwater room liquid; In the liquid of dense hydroecium, obtain the iminodiacetic acid (salt) acid product of content more than 99.9%.
Claims (1)
1. method of utilizing electrodialytic technique separation of glycine and iminodiacetic acid (salt) acid mixture is characterized in that this method comprises following each step:
(1) mixture with glycine and iminodiethanoic acid is dissolved in the water, and it is the aqueous solution of 3%-25% that proportioning becomes solid content;
(2) if the content height of glycine in the mixture is adjusted to the iso-electric point 5.97 of glycine with the pH value of solution, utilize electrodialysis appts to separate, the iso-electric point of glycine was controlled between the 5.80-6.14 when electrodialysis separated;
(3) if the content height of iminodiethanoic acid in the mixture is adjusted to the iso-electric point 1.96 of iminodiethanoic acid with the pH value of solution, utilize electrodialysis appts to separate, the iso-electric point of glycine was controlled between the 1.82-2.13 when electrodialysis separated;
(4) utilize electrodialysis appts to finish the solution of separation of glycine and iminodiethanoic acid after, liquid to electrodialysis appts freshwater room and dense hydroecium the inside carries out concentrating under reduced pressure respectively, be concentrated to the crystallization of finite concentration postcooling, behind the filtration drying, obtain glycine and iminodiacetic acid (salt) acid product respectively;
(5) also can utilize the high pressure reverse osmosis equipment to concentrate to the liquid inside freshwater room or the dense hydroecium earlier, again concentrated solution be carried out concentrating under reduced pressure, be concentrated to the crystallization of finite concentration postcooling, behind the filtration drying, obtain glycine and iminodiacetic acid (salt) acid product respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201010154314A CN101792397A (en) | 2010-04-26 | 2010-04-26 | Method for separating mixture of glycine and iminodiacetic acid by electrodialysis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201010154314A CN101792397A (en) | 2010-04-26 | 2010-04-26 | Method for separating mixture of glycine and iminodiacetic acid by electrodialysis |
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| CN101792397A true CN101792397A (en) | 2010-08-04 |
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| CN201010154314A Pending CN101792397A (en) | 2010-04-26 | 2010-04-26 | Method for separating mixture of glycine and iminodiacetic acid by electrodialysis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103964989A (en) * | 2014-01-27 | 2014-08-06 | 重庆紫光化工股份有限公司 | System for continuously separating and purifying amino acid from water solution of amino acid containing alkaline metal salt |
| CN106349094A (en) * | 2016-08-26 | 2017-01-25 | 重庆紫光国际化工有限责任公司 | Separation and purification method of glycerine and iminodiacetic acid |
-
2010
- 2010-04-26 CN CN201010154314A patent/CN101792397A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103964989A (en) * | 2014-01-27 | 2014-08-06 | 重庆紫光化工股份有限公司 | System for continuously separating and purifying amino acid from water solution of amino acid containing alkaline metal salt |
| CN104003830A (en) * | 2014-01-27 | 2014-08-27 | 重庆紫光化工股份有限公司 | Method for separating amino acid and iminodicarboxylic acid from aqueous solution of alkali metal salt of amino acid |
| CN104003830B (en) * | 2014-01-27 | 2016-08-17 | 重庆紫光化工股份有限公司 | Amino acid separation and the method for iminodicarboxylic acid from the aqueous solution of amino acid whose alkali metal salt |
| CN103964989B (en) * | 2014-01-27 | 2017-12-15 | 重庆紫光化工股份有限公司 | The system that amino acid is continuously isolated and purified from the aqueous solution of the alkali metal salt of amino acid |
| CN106349094A (en) * | 2016-08-26 | 2017-01-25 | 重庆紫光国际化工有限责任公司 | Separation and purification method of glycerine and iminodiacetic acid |
| CN106349094B (en) * | 2016-08-26 | 2018-05-01 | 重庆紫光化工股份有限公司 | A kind of isolation and purification method of glycine and iminodiacetic acid |
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Application publication date: 20100804 |