CN101759360A - Formula of precharging type syringe needle tube - Google Patents
Formula of precharging type syringe needle tube Download PDFInfo
- Publication number
- CN101759360A CN101759360A CN200810237819A CN200810237819A CN101759360A CN 101759360 A CN101759360 A CN 101759360A CN 200810237819 A CN200810237819 A CN 200810237819A CN 200810237819 A CN200810237819 A CN 200810237819A CN 101759360 A CN101759360 A CN 101759360A
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- Prior art keywords
- needle tube
- parts
- oxide
- syringe needle
- type syringe
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Abstract
The invention belongs to the field of a neutral borosilicate glass formula, particularly to a formula of a precharging type syringe needle tube, which is characterized by being prepared from the following raw materials in parts by weight: 75-76 parts of silicon dioxide, 5-6 parts of alumina, 10-11 parts of boron oxide, 0.5-0.6 part of potassium oxide, 7-8 parts of sodium oxide, 0.7-0.8 part of calcium oxide, 0.02-0.03 part of magnesia and 0.01-0.02 part of ferric oxide. The precharging type syringe needle tube prepared by invention has a series of excellent performances of low thermal expansion coefficient (4.0-5.0X10-6/K), good thermal stability, particularly good chemical stability, strong acid, alkali, water and erosion resisting capabilities and good chemical stability. The precharging type syringe needle tube prepared by invention completely conforms to a needle tube detection standard (YBB00062004 a borosilicate glass needle tube for a prefilled syringe).
Description
Technical field
The invention belongs to neutral borosilicate glass prescription field, particularly a kind of prescription of precharging type syringe needle tube.
Background technology
Precharging type syringe has become the first-selected wrapping material of high-grade biotechnological formulation medicine at present, product specification mainly contains 0.5ml, 1.0ml, 2.0ml, 2.25ml, 3.0ml, 5.0ml, 10.0ml, 20.0ml etc., pre-encapsulated injector has short-thick type, slender type again simultaneously, and concrete specification can be produced according to requirement of client.Precharging type syringe needle tube mainly contains neutral borosilicate glass or two kinds of materials of cyclic polyolefin (COC) are formed, why neutral borosilicate glass are ideal injection medicine packings, be because it has excellent barrier properties, and industry think that always neutral borosilicate glass are low for the reaction of injection medicine than plastics; Moreover when adopting neutral borosilicate glass, leaching amount and extraction quantity are also lower.
Summary of the invention
The object of the present invention is to provide a kind of prescription of precharging type syringe needle tube.
The following technical scheme of the concrete employing of the present invention, that is:
A kind of precharging type syringe needle tube is characterized in that, is made by the raw material of following parts by weight:
75～76 parts of silicon-dioxide
5～6 parts in aluminum oxide
10～11 parts of boron oxides
0.5～0.6 part of potassium oxide
7～8 parts of sodium oxides
0.7～0.8 part in calcium oxide
0.02～0.03 part in magnesium oxide
0.01～0.02 part of ferric oxide.
Because the method for making of neutral borosilicate glass belongs to prior art, is not emphasis of the present invention, is not described in detail recipe at this.
Prepared precharging type syringe needle tube of the present invention has a series of premium propertiess: very low thermal expansivity (4.0-5.0X10-6/K) is arranged, good thermal stability, chemical stability is also good, antiacid especially, alkali resistant, anti-water and anti-erosional competency are strong, has good chemical stability.The prepared precharging type syringe needle tube of the present invention meets needle tubing examination criteria (YBB00062004 pre-encapsulated injector borosilicate glass needle tubing) fully.
Embodiment
Embodiment
1, batching: prepare burden according to shown in the following table
Unit (Kg)
| Form | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Silicon-dioxide | ??75 | ??75.5 | ??76 |
| Aluminum oxide | ??6 | ??5.5 | ??5 |
| Boron oxide | ??10 | ??10.5 | ??11 |
| Potassium oxide | ??0.6 | ??0.55 | ??0.5 |
| Sodium oxide | ??7 | ??7.5 | ??8 |
| Calcium oxide | ??0.8 | ??0.75 | ??0.7 |
| Magnesium oxide | ??0.02 | ??0.025 | ??0.03 |
| Ferric oxide | ??0.02 | ??0.015 | ??0.01 |
2, preparation process: batching is selected from each prescription of embodiment 1-3, adopts the method for making preparation of the neutral borosilicate glass of prior art.
Claims (1)
1. the prescription of a precharging type syringe needle tube is characterized in that, is made by the raw material of following parts by weight:
75～76 parts of silicon-dioxide
5～6 parts in aluminum oxide
10～11 parts of boron oxides
0.5～0.6 part of potassium oxide
7～8 parts of sodium oxides
Calcium oxide 0.7～0.8
0.02～0.03 part in magnesium oxide
0.01～0.02 part of ferric oxide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810237819A CN101759360A (en) | 2008-12-02 | 2008-12-02 | Formula of precharging type syringe needle tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810237819A CN101759360A (en) | 2008-12-02 | 2008-12-02 | Formula of precharging type syringe needle tube |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101759360A true CN101759360A (en) | 2010-06-30 |
Family
ID=42490765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810237819A Pending CN101759360A (en) | 2008-12-02 | 2008-12-02 | Formula of precharging type syringe needle tube |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101759360A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104118989A (en) * | 2013-04-26 | 2014-10-29 | 肖特股份有限公司 | Borosilicate glass with improved hydrolytic resistance preferably for use in the pharmaceutical industry |
| CN104261676A (en) * | 2014-09-04 | 2015-01-07 | 东莞市长安东阳光铝业研发有限公司 | Neutral borosilicate glass and application thereof |
-
2008
- 2008-12-02 CN CN200810237819A patent/CN101759360A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104118989A (en) * | 2013-04-26 | 2014-10-29 | 肖特股份有限公司 | Borosilicate glass with improved hydrolytic resistance preferably for use in the pharmaceutical industry |
| US20140323287A1 (en) * | 2013-04-26 | 2014-10-30 | Schott Ag | Borosilicate glass having improved hydrolytic resistance for preferred use in the pharmaceutical sector |
| US9643882B2 (en) * | 2013-04-26 | 2017-05-09 | Schott Ag | Borosilicate glass having improved hydrolytic resistance for preferred use in the pharmaceutical sector |
| CN104118989B (en) * | 2013-04-26 | 2019-06-18 | 肖特股份有限公司 | It is preferred for the Pyrex of the hydrolytic resistance with improvement of field of medicaments |
| CN104261676A (en) * | 2014-09-04 | 2015-01-07 | 东莞市长安东阳光铝业研发有限公司 | Neutral borosilicate glass and application thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Open date: 20100630 |