CN101745157A - Online peritoneal dialysis unit and preparation method - Google Patents
Online peritoneal dialysis unit and preparation method Download PDFInfo
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- CN101745157A CN101745157A CN200810207502A CN200810207502A CN101745157A CN 101745157 A CN101745157 A CN 101745157A CN 200810207502 A CN200810207502 A CN 200810207502A CN 200810207502 A CN200810207502 A CN 200810207502A CN 101745157 A CN101745157 A CN 101745157A
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Abstract
The invention discloses an online peritoneal dialysis unit and preparation method which integrates computer automation control technique, antiosmosis water processing technology and peritoneal dialysis solution concentrating technology. The unit can online prepare peritoneal dialysis solution equal to or more than 30L in 10-20 hour curing process with a peritoneal dialysis solution preparing speed which is equal to or more than 200ml/min, which meets the requirement that the clinic care exchange capacity reaches 50ml/min; automatically completes exchange operating process more than 15-18 times, solves the defects that using the current CAPD technology to realize large-volume exchange is difficult to operate frequently and the APD equipment does not have the function of 30L-36L large-volume exchange function, and provides technical supports for realizing the KT/V value of most patients to be equal to or more than 2.1, realizing the Ccr of more than 70 percent of patients to be equal to or more than 60ml/1.73 square meters, realizing the elimination rate of carbamide to be more than 12ml/min, and improves the survive rate of the patients.
Description
Technical field
The present invention relates to medical instruments field, relate in particular to a kind of online peritoneal dialysis unit and preparation method.
Background technology
Peritoneal dialysis be medical circle confirm " renal failure (uremia) " patient's renal function replacement therapy one of method arranged.Present peritoneal dialysis treatment is to adopt the patient at home from the line operate therapeutic modality basically: the CAPD mode; The mode that perhaps replaces the manually-operated treatment: APD mode by machine.
Which kind of mode of CAPD/APD no matter, all be to use by the pharmaceutical factory by fixing recipe configuration, the packed peritoneal dialysis of 2000ml plastics.Therapeutic modality is: at first the catheter channel of 2000ml/ bag peritoneal dialysis liquid through being retained on the abdominal cavity is fed into the abdominal cavity, peritoneal dialysis liquid stopped 3-4 hour in the abdominal cavity and human body exchanges, discharge is retained in Intraabdominal old liquid and pours into one bag of new liq again, every day 3-4 time repeatedly then.The about 6000ml-10000ml of the total groundwater increment of per day for adults finished treatment on the same day, and uninterruptedly treated all the year round in 10-12 hour.
The clinical research evaluation proves: when dialysis solution and patient's average exchange capacity reached 50ml/min, then most of patient can reach the above patient Ccr 〉=60ml/1.73m in KT/V value 〉=2.1,70%
2, the clearance rate>12ml/min of carbamide.And the KT/V value descended for 0.1/ week, and mortality rises 5%, Ccr decline 5ml/1.73m
2, death risk rises 7%.
One, the problem of the existence of CAPD/APD treatment at present:
1, under current CAPD/APD therapeutic modality, dialysis solution and patient's average exchange capacity is about 16ml/min, therapeutic effect clinical research evaluation proof only has 25%-50% patient's carbamide KT/V value 〉=2.1, fraction patient creatinine clearance rate Ccr 〉=60ml/1.73m
2, the clearance rate 6ml/min of carbamide is unfavorable for reducing the mortality rate of dialysis patient.
2, if dialysis solution and the average exchange capacity of patient rise to 50ml/min, the 3L/h that then need dialyse, the 10-12 hour about 30L-36L of needs dialysis solution.Adopt the CAPD mode, being set as the people pours into 2000ml/ time, the swap operation that manually carries out 15-18 perfusion, indwelling, discharge opeing 10-12 hour domestic demand then, so frequent manually-operated needs every day, continues all the year round to carry out, and no matter patient, medical worker is undoubtedly huge difficulty or will pays through the nose.As the patient is the house peritoneal dialysis treatment, (then need to store three months the winter at cold district then must to carry, store one month at home, every month about 1000L liquid) Yi Shang medication, will hang up 30L-36L liquid on the drip stand every day, almost is impossible realize to overwhelming majority patient worn with age.The storing cost of every patient's great number that about 12 tons of liquid storings will inevitably cause in every year increases the weight of the medical expense burden simultaneously.
3, under current APD treatment French, though machine can be finished 15-18 time swap operation every day,, first: all APD equipment does not all possess the function of exchange of 30L-36L every day; Second: storage, the difficult that still can not solve big quantity of fluid.
4, under present CAPD/APD mode, every bag of employed special PVC plastic packaging bag of peritoneal dialysis solution is about 0.2Kg, every annual 200KgPVC plastic packaging bag that consumes of patient, consume PVC plastics more than 2000 tons at present national every year approximately, cause cost of drugs to rise, increased the consumption of resource and the pollution of environment.As exchange capacity being risen to 30L-36L every day, then the consumption of plastics also will increase about 3 times.
Summary of the invention
Deficiency at the prior art existence, the object of the present invention is to provide and merge the computer automation control technology, Reverse Osmosis Water Treatment Technology and concentrated peritoneal dialysis solution technology, this device can onlinely make 〉=peritoneal dialysis solution of 30L in 10-12 hour therapeutic process, dialysis solution preparation speed 〉=200ml/min has satisfied the requirement that the clinical treatment exchange capacity reaches 50ml/min; Automatically finish above swap operation process 15-18 time, solved and used present CAPD technology to realize that high capacity exchanges the frequent operation difficulty of existence and the shortcoming that APD equipment does not possess 30L-36L high capacity function of exchange, for realizing that most of patient reaches the above patient Ccr 〉=60ml/1.73m in KT/V value 〉=2.1,70%
2, the clearance rate>12ml/min of carbamide, the survival rate that improves the patient provides technical guarantee.
Use " concentrating peritoneal dialysis solution " and online preparation peritoneal dialysis solution technology, both satisfied the requirement that clinical treatment needs exchange capacity reaches 50ml/min, present conventional CAPD/APD mode need be able to be purchased peritoneal dialysis liquid again and be reduced to about 360 bags/year for about 1000 bags/year, gross weight can be reduced to about 0.4 ton/year from 2.2 tons/year, the dialysis solution transporting amount reduces more than 87%, has reduced cost of transportation and storing difficulty significantly.The capacity that concentrates the peritoneal dialysis solution packing reduces, and every patient can be consumed the about 200Kg/ of plastic packaging bag and be reduced to about 80Kg/, and plastics consumption reduces by 60%, has protected environment.
Goal of the invention of the present invention is achieved by the following technical solution:
Online peritoneal dialysis unit comprises display, microcomputer CPU, water pretreatment device, heater, pick off, thermostat, vessel clamp, drain folder, perfusion folder, described microcomputer CPU connects display, water pretreatment device, heater, pick off, thermostat respectively, microcomputer CPU is finished the control of all tubing clamp switches according to program, feeds back to display and shows every information.
The preparation method of online peritoneal dialysis unit is as follows:
One, the preparation of dialysis solution water
The water pretreatment device carries out pretreatment to domestic water, and the reverse osmosis water processor carries out reverse-osmosis treated to water, and remaining antibacterial, thermal source and endotoxin in the antibacterial thermal source filter filtrate, heater heat water makes it meet the temperature of human body needs.Current Reverse Osmosis Water Treatment Technology can be prepared the water for dialysis that complies with the national standard requirements, in clinical treatment, generally be used for directly entering blood of human body through the water for dialysis after " antibacterial thermal source filter " processing, do not found that so far bad is answered.
Two, the preparation of dialysis solution
Needs according to the treatment setting, select the concentrated peritoneal dialysis solution of different components and open corresponding medicinal liquid tubing clamp, make concentrated peritoneal dialysis solution enter dialyzate bag, the amount of liquid medicine that enters is measured by accurate weight sensor, closes corresponding medicinal liquid tubing clamp when the concentrated medicament that enters reaches the seance requirement.Open the pure water folder, the dialysis solution water enters dialyzate bag, measure the inlet of water by accurate weight sensor, make the peritoneal dialysis solution that meets the required composition of seance, concentration, capacity thereby when the water that enters dialyzate bag reaches the needed amount of preparation of seance, close the pure water folder.
Three, dialysis treatment
Perfusion: open perfusion folder and vessel clamp, the dialysis solution for preparing enters the patient abdominal cavity through the processing of thermostat by patient interface.
Keep somewhere: close perfusion folder and vessel clamp, keep the dialysis solution exchange of in the abdominal cavity, dialysing according to setting-up time.Simultaneously, this device preparation process of beginning next time to treat required dialysis solution again (is seen: the preparation of dialysis solution).
Drain: open vessel clamp and drain folder after indwelling time arrives, make to have exchanged the dialysis solution inflow waste fluid bag that finishes in the abdominal cavity, accurate weight sensor is measured effusive waste liquid weight.
Drain: after drain finishes, open the drainage folder and drain waste liquid, prepare the clearancen waste fluid bag for treat drain next time.After finishing said process, this device begins new perfusion, indwelling, drain, the discharge process once of repetition again, up to the exchange number of times of finishing setting.
Four, the setting of parameter and system control
Microcomputer CPU is finished monitoring, man-machine communication's function of control, water quality detection, the equipment operational factor of measurement, temperature control, time control, the hydrotreater of control, the weight sensor of all tubing clamp switches, the calculating of parameters according to program.Display shows every information.
Description of drawings
Fig. 1 is a structural representation of the present invention;
The number in the figure explanation
1-peritoneal dialysis solution 2-dialyzate bag 3-waste fluid bag 4-medicinal liquid tubing clamp
5-pure water folder 6-perfusion folder 7-vessel clamp 8-drain folder
9-drains folder 10-thermostat 11-pick off 12-pick off
13-heater 14-antibacterial thermal source filter 15-reverse osmosis water processor
16-water pretreatment device 17-microcomputer CPU 18-display
The specific embodiment
How further specify the present invention below in conjunction with accompanying drawing realizes:
As shown in Figure 1, water pretreatment device 16 is made up of more medium filter, active carbon filter, demineralized water resin filter device, domestic water becomes demineralized water after handling by preprocessor, and demineralized water has reduced the insoluble matter in the water, chlorine residue, calcium ions and magnesium ions etc.Demineralized water enters reverse osmosis water processor 15 and carries out reverse-osmosis treated, and the ion in the filtering water more than 99%, antibacterial etc. become the water for dialysis that meets relevant national standard.Antibacterial thermal source filter 14 leaches antibacterial remaining in the water for dialysis, thermal source and endotoxin and produces peritoneal dialysis solution preparation water.In the controlling the water circulation process, the monitoring of water electric conductivity, hydraulic pressure is finished by computer.Heater 13 heats the preparation water and to make 36 ℃-37 ℃ of its temperature that meets the human body needs when normal the use; Under disinfection, heater produces high-temperature water more than 90 ℃, and water supply line is carried out sterilization processing.The setting of normal use and disinfection is by artificial setting, and computer display 18 is finished.
Computer control, needs according to the treatment setting, select the concentrated peritoneal dialysis solution 1 of different components and open corresponding medicinal liquid tubing clamp 4, make the corresponding peritoneal dialysis solution that concentrates enter dialyzate bag 2, the amount of liquid medicine that enters is measured by accurate weight sensor 11, closes corresponding medicinal liquid tubing clamp 4 when the concentrated medicament that enters dialyzate bag reaches seance requirement computer-chronograph.Open pure water folder 5, the dialysis solution water enters dialyzate bag 2, measure the inlet of water by accurate weight sensor 12, when the water that enters dialyzate bag reaches the needed amount of preparation of seance, thereby computer cuts out pure water folder 5 and makes the peritoneal dialysis solution that meets the required composition of seance, concentration, capacity.
Open perfusion folder 6 and vessel clamp 7, the dialysis solution for preparing in the dialyzate bag enters the patient abdominal cavity through the processing of thermostat 10 by patient interface, after the liquid perfusion finishes, closes perfusion folder 6 and vessel clamp 7 automatically, and thermostat 10 stops to heat.
According to setting indwelling time, computer keeps cutting out perfusion folder 6 and vessel clamp 7, allows the dialysis solution exchange of dialysing in the abdominal cavity.Simultaneously, this device begins the setting according in advance again automatically, treats required " preparation of dialysis solution water " and " preparation of dialysis solution " process next time.
Indwelling time arrives the back device and opens vessel clamp 7 and drain folder 8 automatically, makes to have exchanged the dialysis solution inflow waste fluid bag 3 that finishes in the abdominal cavity, and 12 pairs of effusive waste liquid weight of accurate weight sensor are measured.
After drain finishes, open drainage folder 9 and drain waste liquid, prepare the clearancen waste fluid bag for treat drain next time.
After finishing said process, this device begins new perfusion, indwelling, drain, the discharge process once of repetition again, up to the exchange number of times of finishing setting.
Operator are by microcomputer CPU 17 and corresponding runs software program, can select and set different therapeutic schemes and (comprising: the concentrated peritoneal dialysis liquid of selecting different glucose contents, groundwater increment, indwelling time, design temperature, indwelling time, treatment exchange number of times etc.), automatically calculate every treatment parameter, control device is finished the control of all tubing clamp switches according to setting process, the weight measurement of weight sensor, measurement and control of temperature, time control, the control of hydrotreater, water quality detection, the monitoring of equipment operational factor and the demonstration of every data, timely alarm when the device appearance is unusual.Finish man-machine communication's function.
Claims (2)
1. online peritoneal dialysis unit and preparation method comprise display, microcomputer CPU, water pretreatment device, reverse osmosis water blood processor, heater, pick off, thermostat, vessel clamp, drain folder, perfusion folder, it is characterized in that: described microcomputer CPU connects display, water pretreatment device, reverse osmosis water blood processor, heater, pick off, thermostat respectively, microcomputer CPU is finished the control of all tubing clamp switches according to program, feeds back to display and shows every information.
2. online peritoneal dialysis unit according to claim 1 and preparation method is characterized in that: described this preparation method comprises:
1) preparation of dialysis solution water: the water pretreatment device carries out pretreatment to domestic water, the reverse osmosis water processor carries out reverse-osmosis treated to water, remaining antibacterial, thermal source and endotoxin in the antibacterial thermal source filter filtrate, heater heat water makes it meet the temperature of human body needs;
2) preparation of dialysis solution: according to the needs of treatment setting, select the concentrated peritoneal dialysis solution of different components and open corresponding medicinal liquid tubing clamp, make concentrated peritoneal dialysis solution enter dialyzate bag, the amount of liquid medicine that enters is measured by accurate weight sensor, when reaching the seance requirement, the concentrated medicament that enters closes corresponding medicinal liquid tubing clamp, open the pure water folder, the dialysis solution water enters dialyzate bag, measure the inlet of water by accurate weight sensor, when the water that enters dialyzate bag reaches the needed amount of preparation of seance, make and meet the required composition of seance thereby close pure water folder, concentration, the peritoneal dialysis solution of capacity;
3) dialysis treatment:
(1) perfusion: open perfusion folder and vessel clamp, the dialysis solution for preparing enters the patient abdominal cavity through the processing of thermostat by patient interface;
(2) keep somewhere: close perfusion folder and vessel clamp, keep the dialysis solution exchange of dialysing according to setting-up time in the abdominal cavity, simultaneously, this device begins to treat the preparation process of required dialysis solution again next time; Open and drain folder, drain last drain and enter waste liquid in the waste fluid bag, prepare the clearancen waste fluid bag for treat drain next time;
(3) drain: open vessel clamp and drain folder after indwelling time arrives, make to have exchanged the dialysis solution inflow waste fluid bag that finishes in the abdominal cavity, accurate weight sensor is measured effusive waste liquid weight;
After finishing said process, this device begins new perfusion, indwelling, the drain process once of repetition again, up to the exchange number of times of finishing setting.
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CN200810207502A CN101745157A (en) | 2008-12-22 | 2008-12-22 | Online peritoneal dialysis unit and preparation method |
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CN200810207502A CN101745157A (en) | 2008-12-22 | 2008-12-22 | Online peritoneal dialysis unit and preparation method |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101843930A (en) * | 2010-06-25 | 2010-09-29 | 董大泉 | Household automated peritoneal dialysis device |
CN102363054A (en) * | 2011-10-27 | 2012-02-29 | 尹良红 | Liquid bag type online liquid dispensing peritoneal dialysis machine |
CN103083746A (en) * | 2013-03-01 | 2013-05-08 | 赵立庆 | Moving dialysis method and device |
CN105555330A (en) * | 2013-09-28 | 2016-05-04 | 弗雷森纽斯医疗护理德国有限责任公司 | Sensor system for detecting phases and/or phase transitions in peritoneal dialysis |
CN109432526A (en) * | 2018-11-13 | 2019-03-08 | 重庆本善医疗设备有限公司 | Quantitatively generate the device and method of peritoneal dialysis liquid online with dry powder |
CN110841125A (en) * | 2019-11-05 | 2020-02-28 | 武汉市中医医院 | Peritoneal dialysis solution supply system |
-
2008
- 2008-12-22 CN CN200810207502A patent/CN101745157A/en active Pending
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101843930A (en) * | 2010-06-25 | 2010-09-29 | 董大泉 | Household automated peritoneal dialysis device |
CN102363054A (en) * | 2011-10-27 | 2012-02-29 | 尹良红 | Liquid bag type online liquid dispensing peritoneal dialysis machine |
CN103083746A (en) * | 2013-03-01 | 2013-05-08 | 赵立庆 | Moving dialysis method and device |
CN105555330A (en) * | 2013-09-28 | 2016-05-04 | 弗雷森纽斯医疗护理德国有限责任公司 | Sensor system for detecting phases and/or phase transitions in peritoneal dialysis |
CN105555330B (en) * | 2013-09-28 | 2018-04-27 | 弗雷森纽斯医疗护理德国有限责任公司 | For detecting the stage in peritoneal dialysis treatment and/or the sensing mechanism of step transition |
US10066983B2 (en) | 2013-09-28 | 2018-09-04 | Fresenius Medical Care Deutschland Gmbh | Sensor system for detection of phases and/or phase transitions in peritoneal dialysis treatments |
CN109432526A (en) * | 2018-11-13 | 2019-03-08 | 重庆本善医疗设备有限公司 | Quantitatively generate the device and method of peritoneal dialysis liquid online with dry powder |
CN110841125A (en) * | 2019-11-05 | 2020-02-28 | 武汉市中医医院 | Peritoneal dialysis solution supply system |
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Open date: 20100623 |