CN101720928A - Combination for preventing and curing degenerative disease of bone and joint - Google Patents
Combination for preventing and curing degenerative disease of bone and joint Download PDFInfo
- Publication number
- CN101720928A CN101720928A CN200810218639A CN200810218639A CN101720928A CN 101720928 A CN101720928 A CN 101720928A CN 200810218639 A CN200810218639 A CN 200810218639A CN 200810218639 A CN200810218639 A CN 200810218639A CN 101720928 A CN101720928 A CN 101720928A
- Authority
- CN
- China
- Prior art keywords
- bone
- parts
- osteoporosis
- preventing
- collagen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention relates to a combination for preventing and curing degenerative diseases, such as osteoporosis, osteoarthritis, and the like, comprising the following components in parts by weight: 3-30 parts of hydrolyzed collagen, 4-40 parts of glucosamine, 1.5-15 parts of calcium amino acid chelate, 0.2-20 parts of stachyose, 0.1-2 parts of vitamins C and 0.0002-0.004 parts of vitamins D3. The invention has the effects of comprehensively supplementing multiple metagenics for organisms, promoting the bone metabolism and the bone formation of human bodies, inhibiting and reducing the osteotrophy loss, inhibiting the generation and the development of the osteoporosis and the osteoarthritis, repairing the damaged articular cartilage, mitigating the pain and the moving obstacle of bone joints, reducing the incidence rate of fracture and disability, and the like and plays an active role in preventing and curing the degenerative diseases, i.e. the osteoporosis, the osteoarthritis, and the like, for the human bodies.
Description
Technical field
The invention belongs to nutraceutical, health food or medicine field.
Background technology
Osteoporosis and osteoarthritis are the DDs that the elderly is generally taken place, for many years, because people lack scientific comprehensive understanding to the pathogenic factor of this class disease, additional calcium agent and some mineral matters have been highlighted as solving osteoporotic main method.Under the situation that the whole people replenish the calcium, osteoporotic phenomenon but never is controlled effectively and reduces.Scientific research shows: these retrogression pathological changes of osteoporosis and osteoarthritis are that loss, the shortage owing to abnormal bone metabolism and multiple osteotrophy thing causes that the minimizing of bone mineral is one of cause of disease.Another important reasons is exactly that bone collagen runs off and minimizing.Bone collagen is the important component that constitutes bone and articular cartilage, and the bone collagen that accounts for bone amount about 1/4, cartilage amount about 4/5 plays fixing mineral matter in bone " support " acts on and keep toughness, elasticity and the anti-impact force etc. of bone and articular cartilage.With advancing age, especially enter the synthetic minimizing of bone collagen behind the person in middle and old age, run off and quicken, lost the effect of " fixing " mineral matter, the bone amount reduces, and bone trabecula attenuates bone and osteoarticular hardness, toughness, elasticity and anti-impact force are weakened, bone becomes fragile and easily fractures, the joint inflammation, pain, limitation of activity even disable.So single additional mineral matter not only can not effectively solve the osteoporosis problem, also can reduce make and take in calcareous in the body and be not easy " deposition " utilization in bone because of the bone collagen that plays " support " fixation, free excessive calcium ion just forms calculus in other organs (as urinary organ) deposition easily, and health is caused new harm.Glucosamine is the elementary cell of glycoprotein and GAG chain in body connective tissue and the articular cartilage matrix, can promote cartilage cell's synthesising physiological glycoprotein and GAG, has the repairing damaged cartilage, increase the articular surface lubrication, enter behind the person in middle and old age glycoprotein in the cartilaginous tissue and GAG is synthetic weakens, the lubricity of articular cavity descends and can cause articular surface damage, inflammation, and joint motion is limited.Additional Glucosamine helps eliminating arthritis, repairs damaged cartilage, alleviates bone joint pain, improves the joint motion situation.
Goal of the invention
The present invention not only forms required multiple essential nutrient for human body provides bone tissue, and this prescription has also solved the human body bone and formed existing still unsolved technical problems such as the digestion, absorption, skeletal deposition of desired nutritional element, fixing, utilization.Having corrected for many years from scientific domain, people prevent and treat the additional incomplete understanding mistaken ideas of osteoporosis nutrient.For bone joint DDs such as osteoporosis provide the scientific and effective method of preventing and treating.Generation, development and the fracture of osteoarticular retrograde affection, the incidence that disables have been reduced.Preventing and treating the whole people has major and immediate significance aspect the DD of bone joint.
Summary of the invention
Composition of the present invention is made up of Hydrolyzed Collagen, Glucosamine, amino acid chelated calcium, stachyose, vitamin C, cholecalciferol, and each composition proportion is by weight: Hydrolyzed Collagen 3-30 part, Glucosamine 4-40 part, amino acid chelated calcium 1.5-15 part, stachyose 0.2-20 part, vitamin C 0.1-2 part, cholecalciferol 0.0002-0.004 part.Usually proportioning is: Hydrolyzed Collagen 10-20 part, Glucosamine 10-30 part, amino acid chelated calcium 5-15 part, stachyose 1-10 part, vitamin C 0.5-1 part, cholecalciferol 0.0005-0.002 part.
Wherein optimum ratio is: 15 parts of Hydrolyzed Collagens, 11 parts of Glucosamines, 8 parts of amino acid chelated calciums, 3 parts of stachyoses, 0.8 part of vitamin C, 0.001 part of cholecalciferol.
Beneficial effect
The present invention is that the pathogenic factor according to osteoporosis, this class DD of osteoarthritis mainly is because bone forms the loss of function reduction and multiple nutrients for bones lacks, especially the loss of bone collagen and bone calcium lacks this scientific evidence, in conjunction with a kind of scientific comprehensive nutrients for bones replenishers of Chinese dietetic nutrition structure and health status preparation.Collagen is the key protein of body connective tissue; body skin, blood vessel, tendon, ligament, bone, articular cartilage etc. are organized support, bonding, heavy burden, connection and protective effect; it is the key substance that bone tissue forms and regenerates; the additional deposition of mineral matters such as calcium in bone that promoted of bone collagen; " fix "; bone density improved, increased toughness, elasticity and the impact resistance of bone, articular cartilage.Adopting Hydrolyzed Collagen in the prescription is the collagen peptide of small-molecular weight, is very easily decomposed by enteron aisle to absorb the bioavailability height.Calcium is the body tooth, and bone etc. are organized important constituent, are keeping bone, the hard and anti-impact force of tooth, and supplement calcium can suppress the loss and the minimizing of bone calcium, increases bone density, delaying osteoporosis speed.Amino acid chelated calcium in the prescription is a kind of organic calcium, proves the highest calcium agent of intestinal absorption rate after deliberation, and the capacity that helps human body is replenished.Stachyose is a natural plant extracts, be described as " super bifidus factor " by scientific circles, it is the trophic factors of beneficial bacteria of intestinal tract, can promote the growth and breeding of probio, improve the enteron aisle ecological environment, further promoted of absorption and the utilization of middle-aged and old enteron aisles each nutrient.Glucosamine is that the major ingredients of natural biological extract chondroitin also is the elementary cell of glycoprotein and GAG chain in the articular cartilage matrix, has the damaged cartilage of repairing tissue, stimulate synovium of joint to produce hyaluronic acid to increase the lubrication of articular surface, help ameliorate osteoarthritis disease, alleviating pain improves joint motion.Vitamin C is one of vitamin of needed by human, participates in multiple physiological activity, has the collagen of participation to generate, and promotes capilary health, improves skin, strengthens effects such as immunity.Its shortage can cause blood vessel, joint, skin function unusual.Ascorbicly additionally can promote the synthetic of collagen in the body.Cholecalciferol can improve body to calcareous absorption and bone calcification.Outstanding effect of the present invention is exactly 1. to provide a kind of comprehensive osteotrophy replenishers, scientific formulation advanced person for human body.2. solved current people prevent and treat the complete or not enough technical problem of osteoporotic osteotrophy thing and understanding on mistaken ideas.3. the present invention can promote human body bone metabolic balance and bone tissue to form, the reparation of bone joint injury cartilage, thus reduce the generation that has suppressed osteoporosis and osteoarthritis by the loss that suppresses bone collagen, bone calcium and other mineral matters, development.Alleviate bone joint pain and moving obstacle, reduced the fracture and the incidence that disables.4. can promote the healing and the recovery of fracture patient.The result shows according to the study: the existing patients with osteoporosis of China is nearly 100,000,000, and old man's incidence of disease is up to more than 50% more than 60 years old.This formula components all adopts natural material, and becoming divided dose all is according to accurate Calculation in the safety standard scope of international food medicine, safe, without any side effects, and human body and environment are not all had any destruction, can eat for a long time.Each constituent stable performance, under the normal temperature state, the shelf-life is more than 2 years, do not have expensive, rare composition, production cost is not high, and of the present invention applying will play a positive role aspect the DDs such as osteoporosis, osteoarthritis preventing and treating the mankind.
Claims (5)
1. composition of preventing and treating bone and joint DD, be made up of Hydrolyzed Collagen, Glucosamine amino acid chelated calcium, stachyose, vitamin C, cholecalciferol, each composition proportion is by weight: the former albumen 3-30 of glue part, Glucosamine 4-40 part, amino acid chelated calcium 1.5-15 part, stachyose 0.2-20 part vitamin C 0.1-2 part, cholecalciferol 0.0002-0.004 part.
2. according to the described composition of claim 1, it is characterized in that each composition proportion is by weight: hydrolysis glue protein 10-20 part, Glucosamine 10-30 part, amino acid chelated calcium 5-15 part, stachyose 1-10 part, the plain C 0.5-1 part of dimension, cholecalciferol 0.0005-0.002 part.
3. according to claim 1 or 2 described compositions, it is characterized in that calcareous is inorganic calcium or organic calcium
4. according to claim 1 or 2 described compositions, it is characterized in that collagen is the bone collagen collagen.
5. according to claim 1 or 2 described compositions, it is characterized in that purposes is the host that is used for food additives food, medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810218639A CN101720928A (en) | 2008-10-27 | 2008-10-27 | Combination for preventing and curing degenerative disease of bone and joint |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810218639A CN101720928A (en) | 2008-10-27 | 2008-10-27 | Combination for preventing and curing degenerative disease of bone and joint |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101720928A true CN101720928A (en) | 2010-06-09 |
Family
ID=42442955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810218639A Pending CN101720928A (en) | 2008-10-27 | 2008-10-27 | Combination for preventing and curing degenerative disease of bone and joint |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101720928A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102224896A (en) * | 2011-05-13 | 2011-10-26 | 营养屋(成都)生物医药有限公司 | Health food for enhancing human immunity and increasing bone mineral density and preparation method thereof |
| CN102499379A (en) * | 2011-11-11 | 2012-06-20 | 国家海洋局第三海洋研究所 | Preparation technology for compound aquatic organism collagen peptide-calcium complex, technology for preparing calcium supplement from complex, and application of calcium supplement |
| CN103494201A (en) * | 2013-10-18 | 2014-01-08 | 大连伍陆柒捌生物工程有限公司 | Osteoarticular disease care product of L-ascorbyl dipalmitate |
| CN103704684A (en) * | 2012-09-29 | 2014-04-09 | 邱多福 | Bone health product |
| CN103919136A (en) * | 2014-04-29 | 2014-07-16 | 吉林大学 | Methionine chelating calcium tablets and processing method thereof |
| CN104621568A (en) * | 2015-03-03 | 2015-05-20 | 北京中国科学院老专家技术中心 | Whole meal for old people |
| RU2648641C2 (en) * | 2016-08-01 | 2018-03-26 | Федеральное государственное унитарное предприятие "Научный центр "Сигнал" | Biologically active additive to the food of chondroprotective action |
| WO2018166807A1 (en) * | 2017-03-15 | 2018-09-20 | Rousselot B.V. | Compositions of hydrolyzed collagen peptides and commensal microorganisms and methods thereof |
| CN111773378A (en) * | 2020-08-11 | 2020-10-16 | 聊城市人民医院 | Mesenchymal stem cell compound injection for osteoarthritis |
| CN116096419A (en) * | 2018-11-28 | 2023-05-09 | 董福田 | Substance for treating and/or preventing motion system diseases, and design method and preparation method thereof |
-
2008
- 2008-10-27 CN CN200810218639A patent/CN101720928A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102224896A (en) * | 2011-05-13 | 2011-10-26 | 营养屋(成都)生物医药有限公司 | Health food for enhancing human immunity and increasing bone mineral density and preparation method thereof |
| CN102499379A (en) * | 2011-11-11 | 2012-06-20 | 国家海洋局第三海洋研究所 | Preparation technology for compound aquatic organism collagen peptide-calcium complex, technology for preparing calcium supplement from complex, and application of calcium supplement |
| CN103704684A (en) * | 2012-09-29 | 2014-04-09 | 邱多福 | Bone health product |
| CN103494201A (en) * | 2013-10-18 | 2014-01-08 | 大连伍陆柒捌生物工程有限公司 | Osteoarticular disease care product of L-ascorbyl dipalmitate |
| CN103919136B (en) * | 2014-04-29 | 2016-07-06 | 吉林大学 | A kind of methionine sequestration calcium tablet and processing method |
| CN103919136A (en) * | 2014-04-29 | 2014-07-16 | 吉林大学 | Methionine chelating calcium tablets and processing method thereof |
| CN104621568A (en) * | 2015-03-03 | 2015-05-20 | 北京中国科学院老专家技术中心 | Whole meal for old people |
| RU2648641C2 (en) * | 2016-08-01 | 2018-03-26 | Федеральное государственное унитарное предприятие "Научный центр "Сигнал" | Biologically active additive to the food of chondroprotective action |
| WO2018166807A1 (en) * | 2017-03-15 | 2018-09-20 | Rousselot B.V. | Compositions of hydrolyzed collagen peptides and commensal microorganisms and methods thereof |
| CN110691604A (en) * | 2017-03-15 | 2020-01-14 | 罗赛洛公司 | Compositions and methods for hydrolyzing collagen peptides and commensal microorganisms |
| US11110147B2 (en) | 2017-03-15 | 2021-09-07 | Rousselot B.V | Collagen hydrolysates as a beneficial prebiotic and their effect on joint inflammation and osteoarthritis |
| CN116096419A (en) * | 2018-11-28 | 2023-05-09 | 董福田 | Substance for treating and/or preventing motion system diseases, and design method and preparation method thereof |
| CN111773378A (en) * | 2020-08-11 | 2020-10-16 | 聊城市人民医院 | Mesenchymal stem cell compound injection for osteoarthritis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101720928A (en) | Combination for preventing and curing degenerative disease of bone and joint | |
| CN101248882B (en) | Nutrition food product with promoting health of bones and bone arthrosis | |
| EP2730286B1 (en) | Composition for maintaining bone health and for treating osteoarthritis and osteoarthrosis of the joints | |
| JP2971579B2 (en) | Amino sugar and glycosaminoglycan compositions for the treatment and recovery of connective tissue | |
| US8703174B2 (en) | Joint preserving nutritional vitamin, mineral and herbal pet supplement | |
| CN104188999A (en) | Composition capable of increasing bone density and improving functions of skeletons and joints and preparation method thereof | |
| CN101181294A (en) | Pharmaceutical composition for curing osteoarthritis | |
| CN106235311A (en) | A kind of compositions promoting skeletal system health and application thereof | |
| CN102423487B (en) | Osteoarticular health-care composition and its application | |
| CN107348522A (en) | A kind of alimentation composition for improving the elderly's kinematic system function and preparation method thereof | |
| CN101711786A (en) | Preparation used for relieving osteoarthropathy and enhancing immunity | |
| CN106072651A (en) | A kind of have compositions increasing bone density, anti-inflammatory and analgesic effect and preparation method thereof | |
| JPWO2013136871A1 (en) | Persulfated chondroitin composition | |
| CN114617267A (en) | Reinforced composite bone peptide and preparation method and application thereof | |
| EP1408988B1 (en) | Compositions of orally administered nutritional supplements to repair articular cartilage | |
| CN103330197A (en) | Health-care food for improving osteoporosis | |
| CN106852936A (en) | Pet zhuanggu joint cream and preparation method thereof | |
| CN106689675A (en) | Glucosamine joint patch for strengthening bones | |
| CN103238839A (en) | Food composition containing collagen used for maintaining joints | |
| CN109464651A (en) | A kind of amelioration of disease induced by metabolic disorder in cartilage healthy food and composite medicine | |
| US20200030349A1 (en) | Physiologically active preparation comprising n-acetyl-glucosamine for the treatment of back pain | |
| ZA200107547B (en) | Compositions based on chondroitin sulphate and chitosan for preventing or treating rheumatic disorders by general administration. | |
| WO2016043668A1 (en) | A composition suitable for vegetarians providing calcium supplementation as well as gout prevention and treatment and the method of preparation thereof | |
| CN108815505A (en) | Improve the composition that middle-aged and the old's bone density and osteoarticular function avoid waist-leg from knotting | |
| US20130065823A1 (en) | Supplement for Strengthening the Muscles of a Human |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100609 |