CN101717445A - Preparing method of egg yolk antibody - Google Patents
Preparing method of egg yolk antibody Download PDFInfo
- Publication number
- CN101717445A CN101717445A CN200910231294A CN200910231294A CN101717445A CN 101717445 A CN101717445 A CN 101717445A CN 200910231294 A CN200910231294 A CN 200910231294A CN 200910231294 A CN200910231294 A CN 200910231294A CN 101717445 A CN101717445 A CN 101717445A
- Authority
- CN
- China
- Prior art keywords
- yolk antibody
- yolk
- antigen
- egg
- mixed solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000002969 egg yolk Anatomy 0.000 title claims abstract description 51
- 238000000034 method Methods 0.000 title claims abstract description 11
- 102000002322 Egg Proteins Human genes 0.000 title abstract description 8
- 108010000912 Egg Proteins Proteins 0.000 title abstract description 8
- 235000013345 egg yolk Nutrition 0.000 title abstract 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000006228 supernatant Substances 0.000 claims abstract description 18
- 239000000427 antigen Substances 0.000 claims abstract description 17
- 102000036639 antigens Human genes 0.000 claims abstract description 17
- 108091007433 antigens Proteins 0.000 claims abstract description 17
- 230000036039 immunity Effects 0.000 claims abstract description 16
- 235000013601 eggs Nutrition 0.000 claims abstract description 14
- 241000287828 Gallus gallus Species 0.000 claims abstract description 10
- 235000011187 glycerol Nutrition 0.000 claims abstract description 9
- 239000002244 precipitate Substances 0.000 claims abstract description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 5
- 238000003756 stirring Methods 0.000 claims abstract description 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 32
- 239000011259 mixed solution Substances 0.000 claims description 20
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 16
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 16
- -1 polyoxyethylene Polymers 0.000 claims description 16
- 239000002504 physiological saline solution Substances 0.000 claims description 12
- 238000005119 centrifugation Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 208000010359 Newcastle Disease Diseases 0.000 claims description 5
- 208000015181 infectious disease Diseases 0.000 claims description 5
- 230000002458 infectious effect Effects 0.000 claims description 5
- 239000007924 injection Substances 0.000 claims description 5
- 238000002347 injection Methods 0.000 claims description 5
- 238000001556 precipitation Methods 0.000 claims description 5
- 208000010884 Bursa disease Diseases 0.000 claims description 4
- 241000700605 Viruses Species 0.000 claims description 4
- 239000000839 emulsion Substances 0.000 claims description 4
- 239000008103 glucose Substances 0.000 claims description 4
- 229940031551 inactivated vaccine Drugs 0.000 claims description 4
- 235000013372 meat Nutrition 0.000 claims description 3
- 210000000689 upper leg Anatomy 0.000 claims description 3
- 230000001900 immune effect Effects 0.000 claims description 2
- 239000000047 product Substances 0.000 abstract description 4
- 230000006978 adaptation Effects 0.000 abstract description 2
- 239000004519 grease Substances 0.000 abstract description 2
- 239000007788 liquid Substances 0.000 abstract description 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 235000013330 chicken meat Nutrition 0.000 abstract 1
- 239000008121 dextrose Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 210000004681 ovum Anatomy 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 238000009461 vacuum packaging Methods 0.000 description 2
- 241000272525 Anas platyrhynchos Species 0.000 description 1
- 208000027312 Bursal disease Diseases 0.000 description 1
- 206010035148 Plague Diseases 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000003452 antibody preparation method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009102312948A CN101717445B (en) | 2009-12-22 | 2009-12-22 | Preparing method of egg yolk antibody |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009102312948A CN101717445B (en) | 2009-12-22 | 2009-12-22 | Preparing method of egg yolk antibody |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101717445A true CN101717445A (en) | 2010-06-02 |
CN101717445B CN101717445B (en) | 2012-06-27 |
Family
ID=42432088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009102312948A Expired - Fee Related CN101717445B (en) | 2009-12-22 | 2009-12-22 | Preparing method of egg yolk antibody |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101717445B (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102716476A (en) * | 2012-05-31 | 2012-10-10 | 郑州后羿制药有限公司 | Cell inactivated vaccine, egg yolk antibody injection, and preparation method of cell inactivated vaccine |
CN104208675A (en) * | 2013-09-30 | 2014-12-17 | 郑州后羿制药有限公司 | Mixed freeze-dried powder for preventing chicken viral diseases and preparation method thereof |
CN112826931A (en) * | 2021-01-06 | 2021-05-25 | 周陶 | Preparation method of anti-HPV and anti-gynecological inflammation composite ovovitellin gel |
-
2009
- 2009-12-22 CN CN2009102312948A patent/CN101717445B/en not_active Expired - Fee Related
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102716476A (en) * | 2012-05-31 | 2012-10-10 | 郑州后羿制药有限公司 | Cell inactivated vaccine, egg yolk antibody injection, and preparation method of cell inactivated vaccine |
CN102716476B (en) * | 2012-05-31 | 2015-04-22 | 郑州后羿制药有限公司 | Cell inactivated vaccine, egg yolk antibody injection, and preparation method of cell inactivated vaccine |
CN104208675A (en) * | 2013-09-30 | 2014-12-17 | 郑州后羿制药有限公司 | Mixed freeze-dried powder for preventing chicken viral diseases and preparation method thereof |
CN104208675B (en) * | 2013-09-30 | 2016-08-17 | 郑州后羿制药有限公司 | A kind of freeze-dried mixed powder of anti-chicken viral diseases and preparation method thereof |
CN112826931A (en) * | 2021-01-06 | 2021-05-25 | 周陶 | Preparation method of anti-HPV and anti-gynecological inflammation composite ovovitellin gel |
Also Published As
Publication number | Publication date |
---|---|
CN101717445B (en) | 2012-06-27 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee |
Owner name: SHANDONG HUAMU TIANYUAN A + H STOCK CO., LTD. Free format text: FORMER NAME: SHANDONG HUAMUTIANYUAN ANIMAL PRODUCTS CO., LTD. |
|
CP03 | Change of name, title or address |
Address after: 250101, B21, North Building B, environmental protection science park, Lixia District (hi tech Zone), Shandong, Ji'nan Patentee after: SHANDONG HUAMUTIANYUAN A & H STOCK Co.,Ltd. Address before: 250101 B21, North Building B, environmental protection science and technology zone, Licheng hi tech Zone, Licheng District, Shandong, Ji'nan Patentee before: Shandong Huamutianyuan Animal Health Product Co.,Ltd. |
|
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20100602 Assignee: JINAN COMPSUN BIO-TECH Co.,Ltd. Assignor: SHANDONG HUAMUTIANYUAN A & H STOCK Co.,Ltd. Contract record no.: 2013370000007 Denomination of invention: Preparing method of egg yolk antibody Granted publication date: 20120627 License type: Exclusive License Record date: 20130125 |
|
LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120627 |
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CF01 | Termination of patent right due to non-payment of annual fee |